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https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20psi28S-2876 | In molecular biology, Small nucleolar RNA psi28S-2876 (also known as snoRNA psi28S-2876) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
This Drosophila-specific snoRNA is a member of the H/ACA box class of snoRNA and is predicted to be responsible for guiding the modification of uridines 2876 and 2956 to pseudouridine in Drosophila 28S rRNA.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20psi28S-3316 | In molecular biology, Small nucleolar RNA psi28S-3316 is a member of the H/ACA class of snoRNA. This family is responsible for guiding the modification of uridine 3316 in Drosophila 28S rRNA to pseudouridine
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20psi28S-3327 | In molecular biology, Small nucleolar RNA psi28S-3327 (also known as snoRNA psi28S-3327) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
This Drosophila specific snoRNA is a member of the H/ACA box class of snoRNA and is predicted to be responsible for guiding the modification of uridine 3327 in Drosophila 28S and U1920 in Drosophila 18S rRNA to pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R12 | In molecular biology, Small nucleolar RNA R12 (also known as snoR12) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoR12 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
snoR12 was identified by computational screen of the rice Oryza sativa genome and is predicted to acts as a methylation guide for 25S ribosomal RNA in plants. snoR12 has been alternatively named snoZ44 in Arabidopsis thaliana and snoZ131 in rice.
References
External links
plant snoRNA database
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R16 | In molecular biology, Small nucleolar RNA R16 is a non-coding RNA (ncRNA) molecule identified in plants which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA R16 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
snoR16 was identified in Arabidopsis thaliana. snoRNA R16 is related to another Arabidopsis snoRNA called R40.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R160 | In molecular biology, Small nucleolar RNA R160 (also known as snoR160) is a non-coding RNA (ncRNA) molecule identified in plants which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoR160 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
snoR160 was identified by computational screening of the rice Oryza sativa and is predicted to acts as a methylation guide for 25S ribosomal RNA in plants. snoR160 has also been alternatively named snoZ270 in rice.
References
External links
plant snoRNA database
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R20 | In molecular biology, Small nucleolar RNA R20 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA R20 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA R20 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R21 | In molecular biology, Small nucleolar RNA R21 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA R21 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA R21 was identified in a screen of Arabidopsis thaliana
.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R24 | In molecular biology, Small nucleolar RNA R24 (also known as snoRNA R24) is a non-coding RNA (ncRNA) molecule identified in plants which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
R24 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
snoR24 was originally identified in Arabidopsis thaliana and is proposed to acts as a methylation guide for 18S ribosomal RNA (rRNA) in plants.
References
External links
plant snoRNA database
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R38 | In molecular biology, Small nucleolar RNA R38 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA R38 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
snoRNA R38 has been identified in human, yeast, Arabidopsis thaliana
and Oryza sativa
. snoRNA R38 guides the methylation of 2'-O-ribose sites in 28S rRNA.
References
External links
Yeast snoRNA page for Small nucleolar RNA R38
SGD page for Small nucleolar RNA R38
snoRNABase page for human snR38A
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R41 | In molecular biology, Small nucleolar RNA R41 (also known as snoR41) is a non-coding RNA (ncRNA) molecule identified in plants which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoR41 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
snoR41 was identified by computational screening the rice Oryza sativa genome and is predicted to act as a methylation guide for 18S and 25S ribosomal RNA (rRNA). snoR41 has been alternatively named snoZ154 and snoZ231 in rice. The 18S methylation site is reported to be homologous to that targeted by U62 in humans but there appears to be little sequence similarity between the two snoRNAs.
References
External links
plant snoRNA database
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R43 | In molecular biology, Small nucleolar RNA R43 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA R43 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA R43 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R66 | In molecular biology, Small nucleolar RNA R66 (also known as snoR66) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoR66 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
snoR66 was identified by a computational screening of the rice Oryza sativa genome and is proposed to acts as a methylation guide for 18S ribosomal RNA in plants. Rice snoR66 has also been alternatively named snoZ269. Its should also not be confused with the snoRNA identified in yeast (Saccharomyces cerevisiae) and called snR66.
References
External links
plant snoRNA database
yeast snoRNA database
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R72 | In molecular biology, Small nucleolar RNA R72 (also known as snoR72) is a non-coding RNA (ncRNA) molecule identified in plants which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoR72 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
snoR72 was originally identified in Arabidopsis thaliana and is predicted to acts as a methylation guide for 25S ribosomal RNA rRNA.
References
External links
plant snoRNA database
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20R79 | In molecular biology, Small nucleolar RNA R79 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA R79 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA R79 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20snoM1 | In molecular biology, Small nucleolar RNA snoM1 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
M1 is a predicted to belong to the H/ACA box class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines. snoM1 seems to be found exclusively in Drosophila species.
References
Further reading
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20snoMBI-87 | In molecular biology, Small nucleolar RNA MBI-87 is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
snoRNA MBI-87 was originally cloned from mouse brain tissues
and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20snoR1 | In molecular biology, the Small nucleolar RNA snoR1 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA snoR1 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA snoR1 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20snoR28 | In molecular biology, Small nucleolar RNA R28 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA R28 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA R28 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20snoR60 | In molecular biology, Small nucleolar RNA snoR60 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA snoR60 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA snoR60 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20snoR86 | In molecular biology, Small nucleolar RNA snoR86 (also known as snoR86) is a non-coding RNA (ncRNA) which modifies other small nuclear RNAs (snRNAs). It is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. Plant snoR86 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20snoR98 | In molecular biology, Small nucleolar RNA snoR98 (also known as snoR98) is a non-coding RNA (ncRNA) which modifies other small nuclear RNAs (snRNAs). It is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. Plant snoR98 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA1 | In molecular biology, SNORA1 (also known as ACA1) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Link to HUGO Gene Nomenclature Committee entry for SNORA1
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA12 | In molecular biology, U108 belongs to the H/ACA family of snoRNAs.
The sequence is predicted to guide the pseudouridylation of the U372 residue in the 28S rRNA subunit. However it has not been reported as a pseudouridylation site.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA13 | In molecular biology, SNORA13 (also known as ACA13) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA14 | In molecular biology, SNORA14 (also known as ACA14) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA15 | In molecular biology, SNORA15 (also known as ACA15) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
This family also includes the mouse MBI-79 sequence.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA17 | In molecular biology, SNORA17 (also known as ACA17) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines. Specifically, it is predicted to guide pseudouridylation of the 28S rRNA at positions U4659 and U4598. It shares the same host gene together with ACA43.
There are many closely related sequences that do not appear to have conserved H and ACA boxes, and may be pseudogenes.
References
Further reading
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA18 | In molecular biology, SNORA18 (also known as ACA18) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20Z157/R69/R10 | In molecular biology, Small nucleolar RNA Z157 (homologous to R69 and R10) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA Z157 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA Z157 was identified in screens of Oryza sativa and Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA19 | In molecular biology, SNORA19 (also known as ACA19) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
The family also includes the mouse sequence MBI-51.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA2 | In molecular biology, SNORA2 (also known as ACA2) is a non-coding RNA (ncRNA) which modifies other small nuclear RNAs (snRNAs). It is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
ACA2 was originally cloned from HeLa cells by association with GAR1 protein. It has the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs. Originally two sequence variants of ACA2 were identified (called ACA2a and ACA2b). Both variants share approximately 66% sequence identity to another snoRNA characterised in the same study called ACA34 (also known as SNORA34). In the human genome all three snoRNAs (ACA2a, ACA2b and ACA34) are found to be located in the introns of the same gene. This gene encodes a predicted protein referred to as FLJ20436.
Both variants of ACA2 have the same two predicted target sites (U4263 and U4282) in 28S ribosomal RNA (rRNA). ACA34 is also predicted to target one of these sites (U4282) in addition to U4269 of 28S rRNA. The sequence similarity, genomic location and the predicted target sites of these three snoRNAs suggest they have been generated by subsequent gene duplications during evolution.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA20 | In molecular biology, SNORA20 (also known as ACA20) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA21 | In molecular biology, SNORA21 (also known as ACA21) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
This family also contains the mouse sequence MBI-3.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA22 | In molecular biology, SNORA22 (also known as ACA22) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20Z159/U59 | In molecular biology, Small nucleolar RNA Z159/U59 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA Z159/U59 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA Z159/U59 was identified in a screen of Oryza sativa.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA24 | In molecular biology, SNORA24 (also known as ACA24) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA25 | In molecular biology, SNORA25 (also known as ACA25) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA26 | In molecular biology, SNORA26 is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
The snoRNA HBI-6 belong to the H/ACA family of snoRNAs, guiding the pseudouridylation of position U4522 of the 28S rRNA. HBI-6 is the human orthologue of mouse MBI-6 snoRNA.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA27 | In molecular biology, SNORA27 (also known as ACA27) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20Z161/Z228 | In molecular biology, Small nucleolar RNA Z161 (homologous to snoRNA Z228) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA Z161 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA Z161 was identified in a screen of Oryza sativa.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA28 | In molecular biology, SNORA28 (also known as ACA28) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
Further reading
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA29 | In molecular biology, SNORA29 (also known as ACA29) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
The family also contains the mouse sequence MBI-39.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA30 | In molecular biology, SNORA30 (also known as ACA30) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of eukaryotic cells. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA' as it 'guides' the modification process.
ACA30 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs based on its structure and the proteins it is associated with. snoRNA ACA30 is predicted to guide the pseudouridylation of U4643 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine(Ψ).
This snoRNA is related to other snoRNAs identified in human (ACA37) and mouse (MBI-26).
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA32 | In molecular biology, SNORA32 (also known as ACA32) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20Z163/Z177%20family | In molecular biology, Small nucleolar RNA Z163 (homologous to snoRNA Z177) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA Z163 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA SNORD54 was identified in a screen of Oryza sativa.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA33 | In molecular biology, SNORA33 (also known as ACA33) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA35 | In molecular biology, for Homo sapiens snoRA35 (also known as HBI-36) is an H/ACA box snoRNA, first cloned from a mouse adult brain cDNA library by Cavaillé et al. (2000), and found to be specifically expressed in the choroid plexus. Its human orthologue, HBI-36 was discovered by a homology search, and was found to be specifically expressed in the brain. Its gene resides in the second intron of the serotonin receptor 2c (5HT-2c) gene, which is predominantly expressed in choroid plexus epithelial cells. The human 5HT-2c mRNA was predicted to be 2'O-methylated by the C/D box snoRNP HBII-52 at a position also subjected to A:I editing. HBI-36 has no documented RNA target.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA38 | In molecular biology, SNORA38 (also known as ACA38) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
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External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA4 | In molecular biology, SNORA4 (also known as ACA4) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
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External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20Z168/Z174 | In molecular biology, Small nucleolar RNA Z168/Z174 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA Z168/Z174 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA Z168/Z174 was identified in a screen of Oryza sativa.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA40 | In molecular biology, the small nucleolar RNA ACA40 belongs to the H/ACA family of snoRNAs and guides the pseudouridylation of 28S rRNA subunit at position U4565. snoRNA ACA40 was discovered using large-scale cloning by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residues 28S rRNA U4546 and 18S rRNA 1174. The pseudouridylation of these residues was reported by Ofengand and Bakin (1997) and Maden (1990). ACA1, ACA8, ACA18, ACA25, ACA32 and ACA40 and the C/D box snoRNAs mgh28S-2409 and mgh28S-2411 share the same host gene (MGC5306).
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA41 | In molecular biology, SNORA41 (also known as ACA41) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
The family also includes the mouse sequence MBI-83.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA42 | In molecular biology, SNORA42 (also known as ACA42) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA43 | In molecular biology, Small nucleolar RNA SNORA43 (also known as ACA43) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA43 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA43 is predicted to guide the pseudouridylation of U4938 of 28S ribosomal RNA (rRNA). Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA44 | In molecular biology, Small nucleolar RNA SNORA44 (also known as ACA44) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA44 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA44 is predicted to guide the pseudouridylation of U822 and U686 of 18S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
snoRNA ACA44 is homologous to the mouse snoRNA sequence MBI-64 described by Hüttenhofer et al in 2001.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA46 | In molecular biology, Small nucleolar RNA SNORA46 (also known as ACA46) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA46 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA46 is predicted to guide the pseudouridylation of U649 of 18S ribosomal RNA (rRNA). Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20Z195/SNORD33%20family | In molecular biology, Small nucleolar RNA Z195/SNORD33 (also known as U33) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA Z195/SNORD33 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA Z195 was identified in a screen of Arabidopsis thaliana.
An experiment that looked at 22 different non-small-cell lung cancer tissues found that SNORD33, SNORD66 and SNORD76 were over-expressed relative to matched noncancerous lung tissues.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA48 | In molecular biology, Small nucleolar RNA SNORA48 is a pseudouridylation guide H/ACA box snoRNA. This snoRNA was cloned in 2004 from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It is predicted to guide the pseudouridylation of residue U3797 of 28S rRNA.
The pseudouridylation of this residue had been reported in 1997. The H/ACA box snoRNAs ACA48 and U67, and the C/D box snoRNA mgU6-77, share the same host gene (EIF4A1).
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA49 | In molecular biology, Small nucleolar RNA ACA49 is a snoRNA, originally cloned in 2004 from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It has no identified target RNA.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA5 | In molecular biology, SNORA5 (also known as ACA5) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20Z196/R39/R59%20family | In molecular biology, Small nucleolar RNA Z196/R39/R59 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA Z196/R39/R59 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Plant snoRNA Z196 was identified in a screen of Arabidopsis thaliana.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA50 | In molecular biology, Small nucleolar RNA SNORA50 (also known as ACA50) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA50 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA50 is predicted to guide the pseudouridylation of U34 and U105 of 18S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA51 | In molecular biology, Small nucleolar RNA SNORA51 (also known as ACA51) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA51 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA52 | In molecular biology, Small nucleolar RNA SNORA52 (also known as ACA52) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA52 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA52 is predicted to guide the pseudouridylation of U3823 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA53 | In molecular biology, the snoRNA ACA53 belongs to the H/ACA family of pseudouridylation guide snoRNAs. This H/ACA box RNA was cloned by Kiss et al. (2004) from a HeLa cell extract immunoprecipitated with an anti-GAR1 antibody. It has no identified target RNA. RNA residues targeted for pseudouridylation by this molecule have not been identified.
References
External links
snoRNAbase entry snoRA53
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA54 | In molecular biology, Small nucleolar RNA SNORA54 (also known as ACA54) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA54 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA54 is predicted to guide the pseudouridylation of U3801 of 28S ribosomal RNA (rRNA). Pseudouridylation is the isomerisation (of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA55 | In molecular biology, Small nucleolar RNA SNORA55 (also known as ACA55) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA55 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA55 is predicted to guide the pseudouridylation of U36 of 18S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA56 | In molecular biology, Small nucleolar RNA SNORA56 (also known as ACA56) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA56 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA56 is predicted to guide the pseudouridylation of U1664 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA57 | In molecular biology, Small nucleolar RNA SNORA57 (also known as U99 and MBI-64) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
ACA57 was originally cloned from a mouse brain library and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA57 is predicted to guide the pseudouridylation of U1004 of 18S ribosomal RNA (rRNA). Pseudouridylation is the isomerisation of the nucleoside uridine to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA58 | In molecular biology, Small nucleolar RNA SNORA58 (also known as ACA58) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
ACA58 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA58 is predicted to guide the pseudouridylation of U3823 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
snoRNA ACA58 is homologous to the mouse snoRNA sequence MBI-12 described in.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA61 | In molecular biology, Small nucleolar RNA SNORA61 (also known as ACA61) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
ACA61 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA61 is predicted to guide the pseudouridylation of U2495 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA62 | In molecular biology, Small nucleolar RNA SNORA62 (E2) belongs to the H/ACA class of snoRNAs.
E2 is involved in the processing of eukaryotic pre-rRNA and has regions of complementarity to 28S rRNA.
E2 is encoded in introns in the gene for a laminin-binding protein.
This family also contains the related ACA6, M2 and MBI-136 snoRNAs.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA63 | In molecular biology, Small nucleolar RNA SNORA63 (E3) belongs to the H/ACA class of snoRNAs, is involved in the processing of eukaryotic pre-rRNA and has regions of complementarity to 18S rRNA. E3 is encoded in introns in the gene for protein synthesis initiation factor 4AII.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA65 | In molecular biology, SNORA65 (also known as U65) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a 'guide RNA'.
U65 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure and has the conserved H/ACA-box motifs.
snoRNA U65 is predicted to guide the pseudouridylation of residues U4373 and U4427 of 28S ribosomal RNA (rRNA).
Pseudouridylation is the isomerisation of the nucleoside uridine to pseudouridine(Ψ). U65 is related to the snoRNA MBII-351 identified in mouse.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA66 | In molecular biology, SNORA66 (also known as U66) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
U66 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. U66 is predicted to guide the pseudouridylation of U119 of 18S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA67 | In molecular biology, snoRNA U67 is a non-coding RNA molecule that belongs to the H/ACA class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines. This snoRNA guides pseudouridylation of position U1445 in 18S rRNA. This RNA is expressed from the intron of the host gene EIF4A1.
References
External links
U67 entry in snoRNABase
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA68 | In molecular biology, Small nucleolar RNA SNORA68 (also known as U68) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
ACA68 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA68 is predicted to guide the pseudouridylation of U4393 of 28S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA69 | In molecular biology, Small nucleolar RNA SNORA69 (also known as U69) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
ACA69 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA69 is predicted to guide the pseudouridylation of U36 of 18S and U69 of 5.8S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA7 | In molecular biology, SNORA7 (also known as ACA7) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
The family also contains the mouse sequence MBI-141.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA71 | In molecular biology, U71 belongs to the H/ACA class of Small nucleolar RNA (snoRNAs). snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs. Targets may include ribosomal and spliceosomal RNAs but the exact function of many snoRNAs, including U71, is unclear.
References
Further reading
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA72 | In molecular biology, small nucleolar RNA SNORA72 (also known as U72) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a "guide RNA".
ACA30 was originally cloned from HeLa cells and belongs to the H/ACA box class of snoRNAs as it has the predicted hairpin-hinge-hairpin-tail structure, has the conserved H/ACA-box motifs and is found associated with GAR1 protein. snoRNA ACA72 is predicted to guide the pseudouridylation of U55 of 5.8S ribosomal RNA (rRNA). Pseudouridylation is the (isomerisation of the nucleoside uridine) to the different isomeric form pseudouridine.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA73 | In molecular biology, the small nucleolar RNA SNORA73 (also called U17/E1 RNA) belongs to the H/ACA class of small nucleolar RNAs (snoRNAs). Vertebrate U17 is intron-encoded and ranges in length from 200-230 nucleotides, longer than most snoRNAs. It is one of the most abundant snoRNAs in human cells and is essential for the cleavage of pre-rRNA within the 5' external transcribed spacer (ETS). This cleavage leads to the formation of 18S rRNA. Regions of the U17 RNA are complementary to rRNA and act as guides for RNA/RNA interactions, although these regions do not seem to be well conserved between organisms.
There is evidence that SNORA73 (isoforms: SNORA73A and SNORA73B) functions as a regulator of chromatin function. SNORA73 is chromatin-associated RNA (caRNA) and stably linked to chromatin. Notably, SNORA73 can bind to PARP1, leading to the activation of its ADPRylation (PAR) function. SNORA73 Interacts with the PARP1 DNA-Binding Domain. In addition, the snoRNA-activated PARP1 ADPRylates DDX21 in cells to promote cell proliferation.
See also
Small nucleolar SNORD12/SNORD106
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA74 | In molecular biology, Small nucleolar RNA SNORA74 (U19) belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class is thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs. Targets may include ribosomal and spliceosomal RNAs but the exact functions of many snoRNAs, including U19, are not confirmed. Co-precipitation of U19 snoRNA with RNase MRP RNA suggests that U19 may be involved in pre-rRNA processing.
References
External links
Small nuclear RNA
Spliceosome
RNA splicing |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA75 | In molecular biology, U23 belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs. Targets include ribosomal and spliceosomal RNAs as well as the Trypanosoma spliced leader RNA (SL RNA) as possibly other, still unknown cellular RNAs. U23 can direct the pseudouridylation of U97 in human 18S rRNA. U23 is encoded within intron 12 of the nucleolin gene in human, mouse, rat chicken, and Xenopus laevis.
References
Further reading
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA8 | In molecular biology, SNORA8 (also known as ACA8) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORA9 | In molecular biology, SNORA9 (also known as ACA9) is a member of the H/ACA class of small nucleolar RNA that guide the sites of modification of uridines to pseudouridines.
References
External links
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD101 | In molecular biology, snoRNA U101 (also known as SNORD101) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA U101 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
U101 was identified by computational screening of the introns of ribosomal protein genes for conserved C/D box sequence motifs and expression experimentally verified by northern blotting. snoRNA U101 resides in intron 3 of the ribosomal protein S12. U101 shares the same host gene with C/D box snoRNA HBII-429, and the H/ACA box snoRNA ACA33.
There is currently no predicted methylation target for U101.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD102 | In molecular biology, snoRNA U102 (also known as SNORD102) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA U102 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
U102 was identified by computational screening of the introns of ribosomal protein genes for conserved C/D box sequence motifs and expression experimentally verified by northern blotting. It is found within intron 2 of the L21 ribosomal protein gene. The H/ACA box snoRNA ACA27 is found in the same host gene within a different intron.
U102 is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue G4020.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD103 | In molecular biology, snoRNA U103 (also known as SNORD103) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA U103 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
U103 was identified by computational screening of the introns of ribosomal protein genes for conserved C/D box sequence motifs and expression experimentally verified by northern blotting.
U103 is predicted to guide the 2'O-ribose methylation of 18S ribosomal RNA (rRNA) residue G601. In both the human and mouse genome there are two U103 gene copies (called U103A or SNORD103A and U103B or SNORD103B) located within introns 17 and 21 of the PUM1 gene.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD105 | In molecular biology, U105 belongs to the C/D family of snoRNAs. It is encoded in an intron of the Peter pan homolog gene and is predicted to guide 2'O-ribose methylation of residue U799 of the small 18S rRNA subunit.
References
External links
snoRNABase page for Small nucleolar RNA SNORD105
Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD115 | In molecular biology, SNORD115 (also known as HBII-52) is a non-coding RNA (ncRNA) molecule known as a small nucleolar RNA which usually functions in guiding the modification of other non-coding RNAs. This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. HBII-52 refers to the human gene, whereas RBII-52 is used for the rat gene and MBII-52 is used for naming the mouse gene.
HBII-52 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
In the human genome, HBII-52 is encoded in a tandemly repeated array with another C/D box snoRNA, HBII-85 (SNORD116), in the Prader-Willi syndrome (PWS) region of chromosome 15. However, a microdeletion in one family of the snoRNA HBII-52 cluster has excluded it from playing a major role in the disease. HBII-52 is found in 47 tandem near identical copies on human chromosome 15q11-13. This locus is maternally imprinted, meaning that only the paternal copy of the locus is transcribed. HBII-52 is exclusively expressed in the brain but is absent in PWS patients. HBII-52 lacks any significant complementarity with ribosomal RNAs, but does have an 18 nucleotide region of conserved complementarity to serotonin 2C receptor mRNA. The serotonin 2C receptor is also expressed in the brain. |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD116 | In molecular biology, SNORD116 (also known as HBII-85) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
SNORD116 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
In the human genome, there are 29 tandemnly repeated copies of SNORD116, followed by 48 copies of another C/D box snoRNA, SNORD115, in the Prader–Willi syndrome (PWS) region of chromosome 15. Unlike most other snoRNAs, SNORD116 is expressed prevalently in the brain (but is absent in PWS patients) and lacks any significant complementarity with ribosomal RNA. Mouse models of PWS show similar symptoms to humans (hyperphagia and growth deficiency), providing further evidence that PWS is directly linked to the deletion of SNORD116.
More evidence comes from the discovery of two individuals that share many traits of PWS sufferers, both have atypical microdeletions on chromosome 15q11–13, the intersection of which contains only the SNORD116 snoRNAs.
The targets of SNORD116 are unknown, however a bioinformatic screen located 23 possible targets withi |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD15 | In molecular biology, SNORD15 (also known as U15) is a non-coding RNA (ncRNA) molecule which functions in the modification of small nuclear RNAs (snRNAs, also a type of ncRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
U15 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. U15 is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA (rRNA) residue A3764.
In humans there are two closely related copies of the U15 snoRNA (called SNORD15A and SNORD15B). They are both encoded in the introns of the ribosomal protein S3. In Xenopus laevis it is located within the introns of ribosomal protein S1
snoR75 from Arabidopsis thaliana and homologues in rice Oryza sativa and other plants are alternatively known as U15, and, despite a significantly shorter sequence length, appear to be related.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD16 | In molecular biology, snoRNA U16 (also known as SNORD16) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA U16 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
U16 is predicted to guide the 2'O-ribose methylation of 18S ribosomal RNA (rRNA) residue A484 and is encoded within an intron of the gene for ribosomal proteins L1 in animals. This snoRNA was independently named MBII-98 in mouse.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD17 | In molecular biology, SNORD17 (also known as HBI-43) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
HBI-43 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
This snoRNA is the human orthologue of mouse HBI-43. HBII-43 is predicted to guide 2'O-ribose methylation of 28s ribosomal RNA (rRNA) at position U3797. This residue (U3797) is also predicted to be pseudouridylated (the uridine residue is converted to pseudouridine) by the H/ACA box snoRNA ACA48.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD18 | In molecular biology, SNORD18 (also known as U18) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
U18 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
In humans and Xenopus laevis there are three closely related copies of U18 (called U18A, U18B, U18C) which are encoded in introns of ribosomal protein L1. In yeast U18 is located in the introns of Elongation Factor 1 beta (EF1-beta). Related snoRNAs in Arabidopsis thaliana and rice Oryza sativa have been named R63 and Z106 respectively. Factors involved in the processing of the intronic snoRNA have recently been elucidated.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD19 | In molecular biology, SNORD19 (also known as HBII-108) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
SNORD19 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
HBII-108 is the human orthologue of the mouse MBII-108 and is predicted to guide 2'O-ribose methylation of the small subunit (SSU) ribosomal RNA (rRNA), 18S, on position G683.
In the human genome snoRNA HBII-108 is located in the introns of the gene nucleostemin (NS), along with another snoRNA HBII-210.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD20 | In molecular biology, snoRNA U20 (also known as SNORD20) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA U20 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
U20 is encoded in intron 11 of the nucleolin gene in human, mouse and rat. It is predicted to guide the 2'O-ribose methylation of 18S ribosomal RNA (rRNA) residue U1804.
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Small nuclear RNA |
https://en.wikipedia.org/wiki/Small%20nucleolar%20RNA%20SNORD21 | In molecular biology, U21 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U21 is encoded within an intron of the gene for ribosomal protein L5 in mammals, but within introns of the ADP ribosylation factor gene in Drosophila. U21 snoRNA has a 13 nucleotide region of complementarity with an invariant region of eukaryotic 28S ribosomal RNA.
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Small nuclear RNA |
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