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https://en.wikipedia.org/wiki/Gullstrand%E2%80%93Painlev%C3%A9%20coordinates
Gullstrand–Painlevé coordinates are a particular set of coordinates for the Schwarzschild metric – a solution to the Einstein field equations which describes a black hole. The ingoing coordinates are such that the time coordinate follows the proper time of a free-falling observer who starts from far away at zero velocity, and the spatial slices are flat. There is no coordinate singularity at the Schwarzschild radius (event horizon). The outgoing ones are simply the time reverse of ingoing coordinates (the time is the proper time along outgoing particles that reach infinity with zero velocity). The solution was proposed independently by Paul Painlevé in 1921 and Allvar Gullstrand in 1922. It was not explicitly shown until 1933 in Lemaître's paper that these solutions were simply coordinate transformations of the usual Schwarzschild solution, although Einstein immediately believed that to be true. Derivation The derivation of GP coordinates requires defining the following coordinate systems and understanding how data measured for events in one coordinate system is interpreted in another coordinate system. Convention: The units for the variables are all geometrized. Time and mass have units in meters. The speed of light in flat spacetime has a value of 1. The gravitational constant has a value of 1. The metric is expressed in the +−−− sign convention. Schwarzschild coordinates A Schwarzschild observer is a far observer or a bookkeeper. He does not directly make measu
https://en.wikipedia.org/wiki/Oxamide
Oxamide is the organic compound with the formula . This white crystalline solid is soluble in ethanol, slightly soluble in water and insoluble in diethyl ether. Oxamide is the diamide derived from oxalic acid, and the hydrate of cyanogen. Preparation Oxamide is produced from hydrogen cyanide, which is oxidized to cyanogen, which is then hydrolyzed. It can also be prepared from formamide by glow-discharge electrolysis. Application The main application is as a substitute for urea in fertilizers. Oxamide hydrolyzes (releases ammonia) very slowly, which is sometimes preferred vs the quick release by urea. It is used as a stabilizer for nitrocellulose preparations. It also finds use in APCP rocket motors as a high performance burn rate suppressant. The use of oxamide in concentrations of 1-3 wt% has shown to slow the linear burn rate while having minimal impact on propellant specific impulse. N,N'-substituted oxamides are supporting ligands for the copper-catalyzed amination and amidation of aryl halides in (Ullmann-Goldberg reaction), including relatively unreactive aryl chloride substrates. Reactions It dehydrates above 350 °C releasing cyanogen. Oxamide derivatives form self-assembled monolayers consisting of a hydrogen bonded network. References Carboxamides
https://en.wikipedia.org/wiki/Speedway%20Grand%20Prix%20of%20Austria
The Speedway Grand Prix of Austria was a speedway event that was a part of the Speedway Grand Prix Series. Previous winners Classification See also Sport in Austria References Austria Grand Prix
https://en.wikipedia.org/wiki/Aluminium%20hydroxide%20oxide
Aluminium hydroxide oxide or aluminium oxyhydroxide, AlO(OH) is found as one of two well defined crystalline phases, which are also known as the minerals boehmite and diaspore. The minerals are important constituents of the aluminium ore, bauxite. List of related compounds and minerals The aluminium oxides, oxide hydroxides, and hydroxides can be summarized as follows: aluminium oxides corundum () aluminium oxide hydroxides diaspore (α-AlO(OH)) boehmite or böhmite (γ-AlO(OH)) akdalaite () (once believed to be ), also called tohdite aluminium hydroxides gibbsite (often designated as γ-, but sometimes as α-, sometimes called hydrargillite or hydrargyllite) bayerite (designated often as α- but sometimes as β-) doyleite nordstrandite References Aluminium compounds
https://en.wikipedia.org/wiki/Trachelomonas
Trachelomonas is a genus of swimming, free-living euglenoids characterized by the presence of a shell-like covering called a lorica. Details of lorica structure determine the classification of distinct species in the genus. The lorica can exist in spherical, elliptical, cylindrical, and pyriform (pear-shaped) forms. The lorica surface can be smooth, punctuate or striate and range from hyaline, to yellow, or brown. These colors are due to the accumulation of ferric hydroxide and manganic oxide deposited with the mucilage and minerals that comprise the lorica. In Trachelomonas, the presence of a lorica obscures cytoplasmic details of the underlying cell. In each Trachelomonas cell, there is a gap at the apex of the lorica from which the flagellum protrudes. Thickening around this gap results in a rim-like or collar-like appearance. During asexual reproduction, the nucleus divides yielding two daughter cells one of which exits through the opening in the lorica. This new cell then synthesizes its own new lorica. History of knowledge Trachelomonas was first described by C. G. Ehrenberg in 1834. Its separation from the genus Strombomonas occurred in 2008 with the discovery of five subclades within Trachelomonas through nuclear SSU and LSU rDNA analyses. Habitat and ecology Trachelomonas is a common, cosmopolitan genus found in acidic to neutral fresh water (pH 4.5-7), often in habitats rich in iron and manganese, and pools rich in organic matter such as peat. These euglenoids hav
https://en.wikipedia.org/wiki/Hat%20notation
A "hat" (circumflex (ˆ)), placed over a symbol is a mathematical notation with various uses. Estimated value In statistics, a circumflex (ˆ), called a "hat", is used to denote an estimator or an estimated value. For example, in the context of errors and residuals, the "hat" over the letter indicates an observable estimate (the residuals) of an unobservable quantity called (the statistical errors). Another example of the hat operator denoting an estimator occurs in simple linear regression. Assuming a model of , with observations of independent variable data and dependent variable data , the estimated model is of the form where is commonly minimized via least squares by finding optimal values of and for the observed data. Hat matrix In statistics, the hat matrix H projects the observed values y of response variable to the predicted values ŷ: Cross product In screw theory, one use of the hat operator is to represent the cross product operation. Since the cross product is a linear transformation, it can be represented as a matrix. The hat operator takes a vector and transforms it into its equivalent matrix. For example, in three dimensions, Unit vector In mathematics, a unit vector in a normed vector space is a vector (often a spatial vector) of length 1. A unit vector is often denoted by a lowercase letter with a circumflex, or "hat", as in (pronounced "v-hat"). Fourier transform The Fourier transform of a function is traditionally denoted by . See also
https://en.wikipedia.org/wiki/Norman%20Tome
Norman Tome (born 20 March 1973) is an Australian soccer player who represented Australia at the 1996 Atlanta Olympics. External links Career Statistics at OzFootball 1973 births Living people Australian men's soccer players Footballers at the 1996 Summer Olympics Olympic soccer players for Australia Bonnyrigg White Eagles FC players Sydney Olympic FC players Marconi Stallions FC players Men's association football forwards Place of birth missing (living people)
https://en.wikipedia.org/wiki/Ernst%20Schweninger
Ernst Schweninger (15 June 1850 – 13 January 1924) was a German physician and naturopath who developed the Schweninger method, a reduction of obesity by the restriction of fluids in the diet. Biography He was born on 15 June 1850 in Freystadt, Upper Palatinate. He studied medicine at the Ludwig Maximilian University of Munich where he received his M.D. in 1870. His appointment to a chair at Berlin in 1884 against the wishes of the medical faculty was largely due to his successful treatment of Otto von Bismarck for obesity. His method was a modification of the method developed by William Banting. He published Dem Andenken Bismarcks in 1899. He retired to private life in Munich in 1905. He died there on 13 January 1924. Schweninger rejected orthodox medicine and embraced naturopathy. He established the first nature cure hospital in Berlin. He was considered to have a doubtful reputation and was distrusted by those in the medical community. See also Georg Richard Lewin References External links 1850 births 1924 deaths 19th-century German physicians Naturopaths People from Neumarkt (district)
https://en.wikipedia.org/wiki/Self-protein
Self-protein refers to all proteins endogenously produced by DNA-level transcription and translation within an organism of interest. This does not include proteins synthesized due to viral infection, but may include those synthesized by commensal bacteria within the intestines. Proteins that are not created within the body of the organism of interest, but nevertheless enter through the bloodstream, a breach in the skin, or a mucous membrane, may be designated as “non-self” and subsequently targeted and attacked by the immune system. Tolerance to self-protein is crucial for overall wellbeing; when the body erroneously identifies self-proteins as “non-self”, the subsequent immune response against endogenous proteins may lead to the development of an autoimmune disease. Examples Of note, the list provided above is not exhaustive; the list does not mention all possible proteins targeted by the provided autoimmune diseases. Identification by the immune system Autoimmune responses and diseases are primarily instigated by T lymphocytes that are incorrectly screened for reactivity to self-protein during cell development. During T-cell development, early T-cell progenitors first move via chemokine gradients from the bone marrow into the thymus, where T-cell receptors are randomly rearranged at the gene level to allow for T-cell receptor generation. These T-cells have the potential to bind to anything, including self-proteins. The immune system must differentiate the T-cells tha
https://en.wikipedia.org/wiki/Small%20Device%20C%20Compiler
The Small Device C Compiler (SDCC) is a free-software, partially retargetable C compiler for 8-bit microcontrollers. It is distributed under the GNU General Public License. The package also contains an assembler, linker, simulator and debugger. As of March 2007, SDCC is the only open-source C compiler for Intel 8051-compatible microcontrollers. In 2011 the compiler was downloaded on average more than 200 times per day. Supported hosts Sources, documentation, and binaries are available for Linux (32-bit and 64-bit), macOS (PPC and 64-bit), and Windows (32-bit and 64-bit). Supported targets The following include binary compatible derivatives: Intel 8031, 8032, 8051, 8052; Maxim/Dallas DS80C390; C8051 Motorola/Freescale/NXP 68HC08 and 68HCS08 Padauk PDK14 and PDK15 Sharp SM83, the CPU found in the Nintendo Game Boy LR35902 SoC STMicroelectronics STM8 Zilog Z80, Z180, eZ80 in Z80 mode; Rabbit Semiconductor 2000, 2000A, 3000, 3000A, 4000; Toshiba TLCS-90; Z80N (ZX Spectrum Next processor). Work in progress: Microchip PIC16 and PIC18. Padauk PDK13. MOS Technology 6502 Obsolete: AVR microcontrollers use to be a supported target, but was made obsolete by avr-gcc in 2010 (SDCC 3.0.0). See also Z88DK - C compiler for Z80-based systems cc65 - C compiler for 6502/65C02 systems References External links SDCC homepage Sandeep Dutta - Anatomy of a Compiler. A Retargetable ANSI-C Compiler. "Circuit Cellar", issue 121, August 2000, page 35 SDCC Open Knowledge Resource
https://en.wikipedia.org/wiki/Eric%20Moe%20%28ice%20hockey%29
Eric Moe (born March 6, 1988, in Timrå, Sweden) is a defenceman playing for Leksands IF hockey team in the Swedish second league, HockeyAllsvenskan. Career statistics International play Played for Sweden in: 2006 World U18 Championships 2008 World Junior Championships (silver medal) International statistics External links References 1988 births Leksands IF players Living people Swedish ice hockey defencemen
https://en.wikipedia.org/wiki/Zyad%20Chaabo
Zyad Barakat Chaabo (; born 1 January 1979) is a Syrian former footballer who played as a striker. Career statistics International Scores and results list Syria's goal tally first. Honours Hutteen Syrian Cup: 2000–01 Al-Jaish Syrian Premier League: 2001–02, 2002–03 Syrian Cup: 2001–02, 2003–04 AFC Cup: 2004 Al-Karamah Syrian Premier League: 2007–08 Syrian Cup: 2007–08 Syria Nehru Cup runner-up: 2007 West Asian Games runner-up: 2005 Individual Best Syrian Footballer: 2003 Syrian Premier League top scorer: 2002–03 Nehru Cup top scorer: 2007 References External links Profile at syrialivesport.com 1979 births Living people People from Latakia Men's association football forwards Syrian men's footballers Syria men's international footballers Taliya SC players Al-Karamah SC players Persepolis F.C. players Al-Jaish SC (Syria) players Hutteen SC players Syrian expatriate men's footballers Expatriate men's footballers in Iran Syrian expatriate sportspeople in Iran Syrian Premier League players
https://en.wikipedia.org/wiki/Mika%20Niskanen
Mika Niskanen (born July 24, 1973 in Helsinki, Finland) is a professional ice hockey defenceman, currently with Ilves in the Finnish elite league SM-liiga. Career statistics Awards Elitserien playoff winner with HV71 in 2004. References External links 1973 births Espoo Blues players Finnish ice hockey defencemen HIFK (ice hockey) players HV71 players Ilves players KalPa players Living people Lahti Pelicans players Timrå IK players Ice hockey people from Helsinki
https://en.wikipedia.org/wiki/Kimmo%20Lotvonen
Kimmo Lotvonen (born January 11, 1976 in Oulu, Finland) is a defenceman for the Leksands IF hockey team in the Swedish HockeyAllsvenskan league. Career statistics References External links 1976 births Finnish ice hockey defencemen Oulun Kärpät players Living people Leksands IF players Lukko players Timrå IK players Ice hockey people from Oulu
https://en.wikipedia.org/wiki/Petri%20Kokko%20%28ice%20hockey%29
Petri Kokko (born February 1, 1975 in Oulu, Finland) is a professional ice hockey defenceman playing for the HC Energie Karlovy Vary hockey team. Career statistics References External links 1975 births Living people Ice hockey people from Oulu Finnish ice hockey defencemen Ilves players SaiPa players Timrå IK players
https://en.wikipedia.org/wiki/PARC
PARC or Parc may refer to: Biology PARC (gene), a eukaryotic gene/protein parC, a bacterial gene coding for subunit A of topoisomerase IV Pulmonary and activation-regulated chemokine, a former name for the protein CCL18 Clubs Pays d'Aix Rugby Club, former name of the French rugby union club now known as Provence Rugby Entertainment Parc, an alias of the Swedish trance artist Jezper Söderlund Parc (film), a 2008 film Organizations PARC (company), the Palo Alto Research Center (formerly Xerox PARC) PARC Management, a theme park and entertainment venue operator Pakistan Agricultural Research Council Photography and the Archive Research Centre, an organisation within University of the Arts London Partners in Amphibian and Reptile Conservation, an organization initiated by the Savannah River Ecology Laboratory devoted to conservation of amphibians and reptiles Portland Anarchist Road Care, a road maintenance organization based in Portland, Oregon President's Appalachian Regional Commission, a predecessor of the Appalachian Regional Commission Places Parc, New York, a census-designated place named for the Plattsburgh Airbase Redevelopment Corporation Parc, Penrhyndeudraeth, a ruined mansion once owned by the Anwyl of Tywyn Family of Gwynedd, Wales Parc (HM Prison), a prison in South Wales Arctic Village Airport (ICAO: PARC), an airport in Arctic Village, Alaska Other Parco (disambiguation) See also Parc station (disambiguation)
https://en.wikipedia.org/wiki/Urban%20ecosystem
In ecology, urban ecosystems are considered a ecosystem functional group within the intensive land-use biome. They are structurally complex ecosystems with highly heterogeneous and dynamic spatial structure that is created and maintained by humans. They include cities, smaller settlements and industrial areas, that are made up of diverse patch types (e.g. buildings, paved surfaces, transport infrastructure, parks and gardens, refuse areas). Urban ecosystems rely on large subsidies of imported water, nutrients, food and other resources. Compared to other natural and artificial ecosystems human population density is high, and their interaction with the different patch types produces emergent properties and complex feedbacks among ecosystem components. In socioecology, urban areas are considered part of a broader social-ecological system in which urban landscapes and urban human communities interact with other landscape elements. Urbanization has large impacts on human and environmental health, and the study of urban ecosystems has led to proposals for sustainable urban designs and approaches to development of city fringe areas that can help reduce negative impact on surrounding environments and promote human well-being. Urban ecosystem research Urban ecology is a relatively new field. Because of this, the research that has been done in this field has yet to become extensive. While there is still plenty of time for growth in the research of this field, there are some key issu
https://en.wikipedia.org/wiki/Rafi%20Yoeli
Rafi Yoeli is an Israeli pilot, inventor, designer of two proposed flying cars (Urban Aeronautics X-Hawk, Tactical Robotics Cormorant), and CEO of Urban Aeronautics Ltd., which he founded in Yavne, Israel in 2000. Early life and education Yoeli was born in Tel Aviv, circa 1950, and later served as a reserve officer in the Israeli Air Force. He attended Technion – Israel Institute of Technology. Career Following his Israeli Air Force service, Yoeli joined Israel Aerospace Industries Ltd., then was with Boeing in Seattle for 18 months. In 1989, Yoeli founded Aero Design & Development Ltd (AD&D, Ltd.), acting as managing director. In 2001, he started his own company in Israel, Urban Aeronautics, to develop "robots and flying machines." During the 2000s and 2010s, Yoeli designed and tested the Tactical Robotics Cormorant, formerly AirMule or Mule, a flying car unmanned aerial vehicle (UAV), built by Tactical Robotics Ltd., another subsidiary of Urban Aeronautics Ltd. Designer Yoeli envisioned a hovering vehicle similar to helicopters, but with rotors below the cockpit and passenger seating above it. He developed a plan for a flying rescue vehicle that, while still able to hover, would not have the restrictions that helicopters have, due to rotors, enabling his flying car to work in crowded terrains as in a city or urban area, where rescue would normally be much harder or impossible. Though initially designing a flying car modeled after a sports car; Yoeli realized that a car
https://en.wikipedia.org/wiki/Haplogroup%20T-M184
Haplogroup T-M184, also known as Haplogroup T, is a human Y-chromosome DNA haplogroup. The unique-event polymorphism that defines this clade is the single-nucleotide polymorphism known as M184. T-M184 is unusual in that it is both geographically widespread and relatively rare. T1 (T-L206) – the numerically dominant primary branch of T-M184 – appears to have originated in Western Asia, and possibly spread from there into East Africa, South Asia, Europe and adjoining regions. T1* may have expanded with the Pre-Pottery Neolithic B culture (PPNB). Subclades of T-M70 appear to have been present in Europe since the Neolithic with Neolithic Farmers and the later dispersal of Jews from the Near East. Finally, the moderately high frequency (∼18%) of T1b* chromosomes in the Lemba of southern Africa supports the hypothesis of a Near Eastern, but not necessarily a Jewish, origin for their paternal line. Structure Subclade structure of Haplogroup T (M184). T1 (L206) T1a (M70/Page46/PF5662) T1a1 (L162/Page21, L454) T1a1a (L208/Page2) T1a1a1 (CTS11451) T1a1a2 (Y16897) T1a1a2a (Z19963) T1a2 (L131) T1a2a (PH141/Y13244) T1a2b (L446) T1a3 (FGC1350/Y11151 ) T1a3a (Y11675/Z9798) T1a3b (FGC1340/Y8614) T2 (PH110) Distribution Overview As a primary branch of haplogroup LT (a.k.a. K1), the basal, undivergent haplogroup T* currently has the alternate phylogenetic name of K1b and is a sibling of haplogroup L* (a.k.a. K1a). (Before 2008, haplogroup T and its subclades were known as haplogroup K
https://en.wikipedia.org/wiki/Langbeinite
Langbeinite is a potassium magnesium sulfate mineral with the chemical formula K2Mg2(SO4)3. Langbeinite crystallizes in the isometric-tetartoidal (cubic) system as transparent colorless or white with pale tints of yellow to green and violet crystalline masses. It has a vitreous luster. The Mohs hardness is 3.5 to 4 and the specific gravity is 2.83. The crystals are piezoelectric. The mineral is an ore of potassium and occurs in marine evaporite deposits in association with carnallite, halite, and sylvite. It was first described in 1891 for an occurrence in Wilhelmshall, Halberstadt, Saxony-Anhalt, Germany, and named for A. Langbein of Leopoldshall, Germany. Langbeinite gives its name to the langbeinites, a family of substances with the same cubic structure, a tetrahedral anion, and large and small cations. Related substances include hydrated salts leonite (K2Mg(SO4)2·4H2O) and picromerite (K2Mg(SO4)2·6H2O). References Sulfate minerals Evaporite Cubic minerals Minerals in space group 198 Minerals described in 1891
https://en.wikipedia.org/wiki/2004%20Palm%20Island%20death%20in%20custody
The 2004 Palm Island death in custody incident relates to the death of an Aboriginal resident of Palm Island, Cameron Doomadgee (also known as "Mulrunji") on Friday, 19 November 2004 in a police cell. The death of Mulrunji led to civic disturbances on the island and a legal, political and media sensation that continued for fourteen years. The Attorney-General of Queensland, Kerry Shine, indicted an Australian police officer for a criminal trial for the first time since the public prosecutor's office was established. The officer, Senior Sergeant Chris Hurley, who was charged for a death in custody, was acquitted by the jury in June 2007. Hurley medically retired from the Gold Coast station of the Queensland Police in 2017 following a string of charges while serving as a police officer including assault and dangerous driving. Police raids and behaviour following the community riot were found to have breached the Racial Discrimination Act 1975, with a record class action settlement of million awarded to victims in May 2018. Two legal questions arose from the death; firstly, whether the taking into custody of Mulrunji was lawful, and secondly, whether the injuries that led to his death were illegally caused by the arresting officer. Politically, this event raised questions relating to the federal government's 1987–1991 Royal Commission into Aboriginal Deaths in Custody and whether its recommendations to prevent deaths in custody had been implemented by the government. The d
https://en.wikipedia.org/wiki/Beira%20Airport
Beira Airport is an airport in Beira, Mozambique . It has 3 asphalt runways. Airlines and destinations Statistics References External links Airports in Mozambique Buildings and structures in Beira, Mozambique Buildings and structures in Sofala Province
https://en.wikipedia.org/wiki/Edna%20Staebler%20Award
The Edna Staebler Award for Creative Non-Fiction is an annual literary award recognizing the previous year's best creative nonfiction book with a "Canadian locale and/or significance" that is a Canadian writer's "first or second published book of any type or genre". It was established by an endowment from Edna Staebler, a literary journalist best known for cookbooks, and was inaugurated in 1991 for publication year 1990. The award is administered by Wilfrid Laurier University's Faculty of Arts. Only submitted books are considered. For purposes of the award, "Creative non-fiction is literary not journalistic. The writer does not merely give information but intimately shares an experience with the reader by telling a factual story using the devices of fiction ... [details deleted]  Rather than emphasizing objectivity, the book should have feeling, and should be a compelling, engaging read." Recipients The panel may "grant or withhold the award in any year." In fact the award has been granted every year and there were two winners in 1993 (published 1992). In the 2020s, the awards were postponed for several years due to the COVID-19 pandemic in Canada. The nominees for 2020 were announced in July 2022, with the winner to be announced in August, and the nominees for 2021 are expected later in the year. Following postponement during the pandemic, a shortlist of nominees was announced on May 18, 2023. 1990s 2000s 2010s 2020s References External links Official website Edn
https://en.wikipedia.org/wiki/Nampula%20Airport
Nampula Airport is an airport in Nampula, Mozambique . In the northeastern part of Mozambique, with two paved runways. Airlines and destinations Statistics References External links Mozambique Airport Authority Airports in Mozambique Buildings and structures in Nampula
https://en.wikipedia.org/wiki/Pemba%20Airport%20%28Mozambique%29
Pemba Airport is a small international airport in Pemba, Mozambique. Airlines and destinations Passenger Cargo Statistics References Airports in Mozambique Buildings and structures in Cabo Delgado Province
https://en.wikipedia.org/wiki/Multiuser%20detection
Multiuser detection deals with demodulation of the mutually interfering digital streams of information that occur in areas such as wireless communications, high-speed data transmission, DSL, satellite communication, digital television, and magnetic recording. It is also being currently investigated for demodulation in low-power inter-chip and intra-chip communication. Multiuser detection encompasses both receiver technologies devoted to joint detection of all the interfering signals or to single-user receivers which are interested in recovering only one user but are robustified against multiuser interference and not just background noise. Mutual interference is unavoidable in modern spectrally efficient wireless systems: even when using orthogonal multiplexing systems such as TDMA, synchronous CDMA or OFDMA, multiuser interference originates from channel distortion and from out-of-cell interference. In addition, in multi-antenna (MIMO) systems, the digitally modulated streams emanating from different antennas interfere at the receiver, and the MIMO receiver uses multiuser detection techniques to separate them. By exploiting the structure of the interfering signals, multiuser detection can increase spectral efficiency, receiver sensitivity, and the number of users the system can sustain. Because of the mistaken belief in some quarters of the spread spectrum community that little could be gained from receivers more sophisticated than the single-user matched filter, multiuser
https://en.wikipedia.org/wiki/Quelimane%20Airport
Quelimane Airport is an airport in Quelimane, Mozambique . Airlines and destinations Statistics Accidents and incidents On 23 February 1944 a Lockheed L-14 CR-AAV of DETA - Direcção de Exploração de Transportes Aéreos crashed on takeoff at Quelimane Airport, killing all 13 on board. On 21 April 1988, Douglas C-47A N47FE of African Air Carriers was damaged beyond economic repair in a take-off accident. Both crew were killed, one other person on board was seriously injured. The aircraft may have been shot down. On 27 March 1983 a Boeing 737-200 C9-BAB LAM Mozambique Airlines had an Undercarriage failure after landing some 400 metres (1,300 ft) short of the runway at Quelimane Airport. All 110 on board survived. References Airports in Mozambique Buildings and structures in Zambezia Province
https://en.wikipedia.org/wiki/Benin%20Airport
Benin Airport is an airport serving Benin City, the capital of Edo State in Nigeria. The runway is in the middle of the city. Airlines and destinations Statistics See also Transport in Nigeria List of airports in Nigeria List of the busiest airports in Africa References External links SkyVector Aeronautical Charts OurAirports - Benin Airports in Nigeria Benin City
https://en.wikipedia.org/wiki/TSR2
TSR2 may refer to: the TSR2 (gene), a human gene encoding a protein involved in ribosome biogenesis the BAC TSR-2, British Aircraft Corporation Tactical Strike/Reconnaissance 2 the former name of RTS Deux, a public television channel in Switzerland owned by Radio Télévision Suisse
https://en.wikipedia.org/wiki/ICSD
ICSD may refer to: Interfaith Center for Sustainable Development Inorganic Crystal Structure Database International Central Securities Depository International Classification of Sleep Disorders Ithaca City School District International Committee of Sports for the Deaf
https://en.wikipedia.org/wiki/Smederna
Smederna is a motorcycle speedway club based in Eskilstuna, Sweden. The club competes in the highest speedway league in Sweden called the Elitserien and race its home matches at Smedstadion outside Eskilstuna. Smederna has won six Swedish Speedway Team Championships. Venues Snälltorpet The team raced at Snälltorpet from the 1953 season until the 2001 season, when the land was sold by Eskilstuna Municipality. The track was also used for 1976 Swedish final and the 1976 Speedway World Pairs Championship. Smedstadion Since 2002, the team have raced at the Smedstadion. History In 1948 the speedway team Griparna (English: the Griffins) started to race in the Swedish leagues. The team was co-run by motorcycle sport clubs SMK Södermanland, Nyköpings MS and Eskilstuna MK and was based in Nyköping, however some of their home matches took place in Eskilstuna. 1951 the team changed name to Smederna (English: the Blacksmiths) and started to race all home matches in Eskilstuna. Until 1953 the home track had been Tunavallens B-plan which was not an actual speedway arena. But that year Smederna moved to the new speedway arena Snälltorpet. But Smederna would only race at Snälltorpet for a few years before closing the team down in 1955. After eight years SMK Södermanland decided to take up speedway again and in 1963 Smederna started in the third and lowest division in Swedish speedway. In 1967, the club advanced to the second division and in 1971 to the first and highest division. In the
https://en.wikipedia.org/wiki/Forward%20kinematics
In robot kinematics, forward kinematics refers to the use of the kinematic equations of a robot to compute the position of the end-effector from specified values for the joint parameters. The kinematics equations of the robot are used in robotics, computer games, and animation. The reverse process, that computes the joint parameters that achieve a specified position of the end-effector, is known as inverse kinematics. Kinematics equations The kinematics equations for the series chain of a robot are obtained using a rigid transformation [Z] to characterize the relative movement allowed at each joint and separate rigid transformation [X] to define the dimensions of each link. The result is a sequence of rigid transformations alternating joint and link transformations from the base of the chain to its end link, which is equated to the specified position for the end link, where [T] is the transformation locating the end-link. These equations are called the kinematics equations of the serial chain. Link transformations In 1955, Jacques Denavit and Richard Hartenberg introduced a convention for the definition of the joint matrices [Z] and link matrices [X] to standardize the coordinate frame for spatial linkages. This convention positions the joint frame so that it consists of a screw displacement along the Z-axis and it positions the link frame so it consists of a screw displacement along the X-axis, Using this notation, each transformation-link goes along a serial chai
https://en.wikipedia.org/wiki/Thomas%20Knutson
Thomas R. Knutson is a climate modeller at the US Geophysical Fluid Dynamics Laboratory, a division of the National Oceanic and Atmospheric Administration (NOAA). His research covers hurricane activity, the link between climate change and hurricane incidence and intensity, and climate change detection and attribution. Biography He served as a contributing author on working group 1 of the IPCC Fourth Assessment Report. He is an Associate Editor of the American Meteorological Society's Journal of Climate. He has published in Science, Proceedings of the National Academy of Sciences, Journal of Geophysical Research, Journal of Climate, Tropical Cyclone Research and Review, Tellus A and the Bulletin of the American Meteorological Society. In 2004, Knutson published a paper suggesting that increases in atmospheric carbon dioxide would lead to more intense hurricanes. This finding was subsequently supported by independent research. Knutson was invited to discuss his thesis on Ron Reagan's MSNBC talk show, but the invitation was withdrawn after the White House intervened. Selected works References External links GFDL home page biographical sketch Donaghy, T., et al. (2007) "Atmosphere of Pressure" a report of the Government Accountability Project (Cambridge, Mass.: UCS Publications), page 30 Living people Year of birth missing (living people) National Oceanic and Atmospheric Administration personnel American climatologists Intergovernmental Panel on Climate Change contribu
https://en.wikipedia.org/wiki/Selective%20adsorption
In surface science, selective adsorption is the effect when minima associated with bound-state resonances occur in specular intensity in atom-surface scattering. In crystal growth, selective adsorption refers to the phenomenon where adsorbing molecules attach preferentially to certain crystal faces. An example of selective adsorption can be demonstrated in the growth of Rochelle salt crystals. If copper ions are added to solution during the growth process, some crystal faces will slow down as copper apparently becomes a barrier to adsorption. However, by then adding sodium hydroxide to the solution, the preferred crystal faces will change once again. Discovery Pronounced intensity minima were first observed in 1930 by Theodor Estermann, Otto Frisch, and Otto Stern, during a series of gas-surface interaction experiments attempting to demonstrate the wave nature of atoms and molecules. The phenomenon has been explained in 1936 by John Lennard-Jones and Devonshire in terms of resonant transitions to bound surface states. Significance The selective adsorption binding energies can supply information on the gas-surface interaction potentials by yielding the vibrational energy spectrum of the gas atom bound to the surface. Starting from the 1970s, it has been extensively studied, both theoretically and experimentally. Energy levels measured with this technique are available for many systems. References Surface science
https://en.wikipedia.org/wiki/List%20of%20Swindon%20Town%20F.C.%20records%20and%20statistics
This page details Swindon Town Football Club records. Player records Appearances Youngest first-team player – Paul Rideout, 16 years 107 days (v. Hull City, 29 November 1980) Most appearances As of 1 February 2007. (Former players only, competitive matches only, includes appearances as substitute): Goalscorers Most goals in a season – 48, Harry Morris (1926–27) Most League goals in a season – 47, Harry Morris, (1926–27) Most goals in a single match – 5 Harry Morris (v. Queens Park Rangers, Third Division South, 18 December 1926) Harry Morris (v. Norwich City, Third Division South, 26 April 1930) Keith East (v. Mansfield Town, Third Division, 20 November 1965) Most goals in the League – 216, Harry Morris Top scorers As of 18 November 2006 (competitive matches only): Club records Wins Most League wins in a season – 32 in 46 matches, Fourth Division, 1985–86 Fewest League wins in a season – 0 in 16 matches, Western League, 1901–02 2 in 16 matches, Western League, 1900–01 2 in 30 matches, Southern League First Division, 1901–02 Defeats Most League defeats in a season – 26 in 46 matches, First Division, 1999–2000 Fewest League defeats in a season – 2 in 8 matches, Western League, 1898–99 4 in 46 matches, Second Division, 1995–96 Goals Most League goals scored in a season – 100 in 42 matches, Third Division South, 1926–27 Fewest League goals scored in a season – 7 in 6 matches, Western League, 1899–1900 17 in 30 matches, Southern League First Division, 1901–02
https://en.wikipedia.org/wiki/Diyan%20Donchev
Diyan Donchev (; born 8 January 1974 in Varna) is a former Bulgarian footballer. As a player, he was a defender and midfielder from 1992 to 2012. He played for Spartak Varna and Lokomotiv Sofia, having also had spells with Greek side AEK Athens, Cherno More, Sportist Svoge and Dorostol Silistra. He was capped once for the Bulgarian team in 1999. International career In March 1999 the Bulgarian national coach Dimitar Dimitrov called Donchev in Bulgaria national football team for friendly match against Ukraine. Diyan made his debut, but the result of the match was a 0:1 loss for Bulgaria. External links 1974 births Living people Bulgarian men's footballers Bulgaria men's international footballers First Professional Football League (Bulgaria) players Super League Greece players FC Spartak Varna players AEK Athens F.C. players FC Lokomotiv 1929 Sofia players PFC Cherno More Varna players FC Sportist Svoge players Bulgarian expatriate men's footballers Expatriate men's footballers in Greece Men's association football defenders Footballers from Varna, Bulgaria
https://en.wikipedia.org/wiki/Homegroup
Homegroup may refer to: Cell group, a church organization Windows HomeGroup, a home network feature that was introduced in Windows 7 and removed from Windows 10 version 1803
https://en.wikipedia.org/wiki/Drain-induced%20barrier%20lowering
Drain-induced barrier lowering (DIBL) is a short-channel effect in MOSFETs referring originally to a reduction of threshold voltage of the transistor at higher drain voltages. In a classic planar field-effect transistor with a long channel, the bottleneck in channel formation occurs far enough from the drain contact that it is electrostatically shielded from the drain by the combination of the substrate and gate, and so classically the threshold voltage was independent of drain voltage. In short-channel devices this is no longer true: The drain is close enough to gate the channel, and so a high drain voltage can open the bottleneck and turn on the transistor prematurely. The origin of the threshold decrease can be understood as a consequence of charge neutrality: the Yau charge-sharing model. The combined charge in the depletion region of the device and that in the channel of the device is balanced by three electrode charges: the gate, the source and the drain. As drain voltage is increased, the depletion region of the p-n junction between the drain and body increases in size and extends under the gate, so the drain assumes a greater portion of the burden of balancing depletion region charge, leaving a smaller burden for the gate. As a result, the charge present on the gate retains charge balance by attracting more carriers into the channel, an effect equivalent to lowering the threshold voltage of the device. In effect, the channel becomes more attractive for electrons. I
https://en.wikipedia.org/wiki/Qualitative%20variation
An index of qualitative variation (IQV) is a measure of statistical dispersion in nominal distributions. There are a variety of these, but they have been relatively little-studied in the statistics literature. The simplest is the variation ratio, while more complex indices include the information entropy. Properties There are several types of indices used for the analysis of nominal data. Several are standard statistics that are used elsewhere - range, standard deviation, variance, mean deviation, coefficient of variation, median absolute deviation, interquartile range and quartile deviation. In addition to these several statistics have been developed with nominal data in mind. A number have been summarized and devised by Wilcox , , who requires the following standardization properties to be satisfied: Variation varies between 0 and 1. Variation is 0 if and only if all cases belong to a single category. Variation is 1 if and only if cases are evenly divided across all categories. In particular, the value of these standardized indices does not depend on the number of categories or number of samples. For any index, the closer to uniform the distribution, the larger the variance, and the larger the differences in frequencies across categories, the smaller the variance. Indices of qualitative variation are then analogous to information entropy, which is minimized when all cases belong to a single category and maximized in a uniform distribution. Indeed, information entro
https://en.wikipedia.org/wiki/Deviation%20%28statistics%29
In mathematics and statistics, deviation is a measure of difference between the observed value of a variable and some other value, often that variable's mean. The sign of the deviation reports the direction of that difference (the deviation is positive when the observed value exceeds the reference value). The magnitude of the value indicates the size of the difference. Types A deviation that is a difference between an observed value and the true value of a quantity of interest (where true value denotes the Expected Value, such as the population mean) is an error. A deviation that is the difference between the observed value and an estimate of the true value (e.g. the sample mean; the Expected Value of a sample can be used as an estimate of the Expected Value of the population) is a residual. These concepts are applicable for data at the interval and ratio levels of measurement. Unsigned or absolute deviation In statistics, the absolute deviation of an element of a data set is the absolute difference between that element and a given point. Typically the deviation is reckoned from the central value, being construed as some type of average, most often the median or sometimes the mean of the data set: where Di is the absolute deviation, xi is the data element, m(X) is the chosen measure of central tendency of the data set—sometimes the mean (), but most often the median. Measures Mean signed deviation For an unbiased estimator, the average of the signed deviations acr
https://en.wikipedia.org/wiki/Henry%20T.%20Sampson
Henry Thomas Sampson Jr. (April 22, 1934 – June 4, 2015) was an American engineer, inventor and film historian who created the gamma-electric cell in 1972 — a device with the main goal of generating auxiliary power from the shielding of a nuclear reactor. He wrote wrote Blacks in Black and White: A Source Book on Black Films, The Ghost Walks: A Chronological History of Blacks in Show Business, 1865-1910, and the two volume Singin' on the Ether Waves: a Chronological History of African Americans in Radio and Television Programming, 1925–1955. Early life Henry Thomas Sampson was born on April 22, 1934, in Jackson, Mississippi, to Henry T. Sampson Sr. and Esther B. (Ellis) Sampson. He graduated from Jackson's Lanier High School in 1951. He then attended Morehouse College in Atlanta, before transferring to Purdue University, where he became a member of the Omega Psi Phi fraternity. He received a Bachelor's degree in chemical engineering from Purdue University in 1956. He graduated with an MS degree in engineering from the University of California, Los Angeles, in 1961. Sampson also received an MS in Nuclear Engineering from the University of Illinois Urbana-Champaign in 1965, and his PhD in 1967. He was the first African American to earn a PhD. in nuclear engineering in the United States.{{}} Early career He was a member of the United States Navy from 1962 until 1964. Sampson was employed as a chemical at the Naval Air Weapons Station China Lake U.S. Naval Weapons Center,
https://en.wikipedia.org/wiki/Univariate%20distribution
In statistics, a univariate distribution is a probability distribution of only one random variable. This is in contrast to a multivariate distribution, the probability distribution of a random vector (consisting of multiple random variables). Examples One of the simplest examples of a discrete univariate distribution is the discrete uniform distribution, where all elements of a finite set are equally likely. It is the probability model for the outcomes of tossing a fair coin, rolling a fair die, etc. The univariate continuous uniform distribution on an interval [a, b] has the property that all sub-intervals of the same length are equally likely. Other examples of discrete univariate distributions include the binomial, geometric, negative binomial, and Poisson distributions. At least 750 univariate discrete distributions have been reported in the literature. Examples of commonly applied continuous univariate distributions include the normal distribution, Student's t distribution, chisquare distribution, F distribution, exponential and gamma distributions. See also Univariate Bivariate distribution List of probability distributions References Further reading Types of probability distributions
https://en.wikipedia.org/wiki/Ruppeiner%20geometry
Ruppeiner geometry is thermodynamic geometry (a type of information geometry) using the language of Riemannian geometry to study thermodynamics. George Ruppeiner proposed it in 1979. He claimed that thermodynamic systems can be represented by Riemannian geometry, and that statistical properties can be derived from the model. This geometrical model is based on the inclusion of the theory of fluctuations into the axioms of equilibrium thermodynamics, namely, there exist equilibrium states which can be represented by points on two-dimensional surface (manifold) and the distance between these equilibrium states is related to the fluctuation between them. This concept is associated to probabilities, i.e. the less probable a fluctuation between states, the further apart they are. This can be recognized if one considers the metric tensor gij in the distance formula (line element) between the two equilibrium states where the matrix of coefficients gij is the symmetric metric tensor which is called a Ruppeiner metric, defined as a negative Hessian of the entropy function where U is the internal energy (mass) of the system and Na refers to the extensive parameters of the system. Mathematically, the Ruppeiner geometry is one particular type of information geometry and it is similar to the Fisher-Rao metric used in mathematical statistics. The Ruppeiner metric can be understood as the thermodynamic limit (large systems limit) of the more general Fisher information metric. For small s
https://en.wikipedia.org/wiki/Protein%20C%20inhibitor
Protein C inhibitor (PCI, SERPINA5) is a serine protease inhibitor (serpin) that limits the activity of protein C (an anticoagulant). An N-terminal fragment of PCI is a possible serum biomarker for prostate cancer. Protein C inhibitor is activated by heparin against thrombin. Protein C inhibitor (PCI) is serine protease inhibitor of serpin type that is found in most tissues and fluids, including blood plasma, seminal plasma and urine of human. It is a 52kD glycoprotein and belongs to serine protease inhibitor ( Serpin) super family of protein. In the beginning protein C Inhibitor (PCI) was identified as an inhibitor of activated protein C (APC), it is currently clear that this inhibitor has an expansive specificity, inhibiting several blood coagulation enzymes counting thrombin and factor Xa. Isolation In the beginning, protein C inhibitor(PCI) was originally identified in human plasma by Griffin and Marlar and first isolation was performed by Suzuki et al. Protein C inhibitor (PCI) can be isolated from human plasma using an ordinary chromatographic procedure consisting of barium citrate adsorption, polyethylene glycol fractionation, DEAE-Sepharose CL-6B treatment, ammonium sulfate fractionation, dextran sulfate-agarose chromatography, gel filtration on ACA-44, and DEAE-Sephacel chromatography. Structure The structure (primary structure) of protein C inhibitor was deduced from its cDNA nucleotide sequence. The human Protein C inhibitor have 19 amino acid signal peptide.
https://en.wikipedia.org/wiki/Adamalysin
Adamalysin (, Crotalus adamanteus metalloendopeptidase, proteinase I and II, Crotalus adamanteus venom proteinase II, adamalysin II) is an enzyme. This enzyme catalyses the following chemical reaction Cleavage of Phe1-Val, His5-Leu, His10-Leu, Ala14-Leu, Leu15-Tyr, and Tyr16-Leu of insulin B chain This enzyme is present in the venom of the eastern diamondback rattlesnake (Crotalus adamanteus). See also A disintegrin and metalloproteinase References External links EC 3.4.24
https://en.wikipedia.org/wiki/Allysine
Allysine is a derivative of lysine that features a formyl group in place of the terminal amine. The free amino acid does not exist, but the allysine residue does. It is produced by aerobic oxidation of lysine residues by the enzyme lysyl oxidase. The transformation is an example of a post-translational modification. The semialdehyde form exists in equilibrium with a cyclic derivative. Allysine is involved in the production of elastin and collagen. Increased allysine concentration in tissues has been correlated to the presence of fibrosis. Allysine residues react with sodium 2-naphthol-6-sulfonate to produce a fluorescent bis-naphtol-allysine product. In another assay, allysine-containing proteins are reduced with sodium borohydride to give a peptide containing the 6-hydroxynorleucine (6-hydroxy-2-aminocaproic acid) residue, which (unlike allysine) is stable to proteolysis. Further reading See also Saccharopine References Alpha-Amino acids Aldehydes Aldehydic acids
https://en.wikipedia.org/wiki/Isodesmosine
Isodesmosine is a lysine derivative found in elastin. Isodesmosine is an isomeric pyridinium-based amino acid resulting from the condensation of four lysine residues between elastin proteins by lysyl-oxidase. These represent ideal biomarkers for monitoring elastin turnover because these special cross-links are only found in mature elastin in mammals. See also Desmosine References Alpha-Amino acids
https://en.wikipedia.org/wiki/Azaz
Azaz () is a city in northwest Syria, roughly north-northwest of Aleppo. According to the Syria Central Bureau of Statistics (CBS), Azaz had a population of 31,623 in the 2004 census. , its inhabitants were almost entirely Sunni Muslims, mostly Arabs but also some Kurds and Turkmen. It is historically significant as the site of the Battle of Azaz between the Crusader States and the Seljuk Turks on June 11, 1125. It is close to a Syria–Turkey border crossing, which enters Turkey at Öncüpınar, south of the city of Kilis. It is the capital of the Syrian Interim Government. History The city was known in ancient times with different names: in Hurrian as Azazuwa, in Medieval Greek as Αζάζιον (Azázion), in Old Aramaic as Ḥzz (later evolved in Neo-Assyrian as Ḫazazu). Early Islamic period In excavations of the site of Tell Azaz, considerable quantities of ceramics from the early and middle Islamic periods were found. Despite the importance of Azaz as indicated by archaeological finds, the settlement was rarely mentioned in Islamic texts prior to the 12th century. However, a visit to the town by the Muslim musician Ishaq al-Mawsili (767–850) gives some indication of Azaz's importance during Abbasid rule. The Hamdanids of Aleppo (945–1002) built a brick citadel at Azaz. It was a square fortress with two enclosures, situated atop a tell. On 10 August 1030, Tubbal near Azaz became the scene of a humiliating defeat of the Byzantine emperor Romanos III at the hands of the Mirdasids.
https://en.wikipedia.org/wiki/AMELY
Amelogenin, Y isoform is a protein that in humans is encoded by the AMELY gene. AMELY is located on the Y chromosome and encodes a form of amelogenin. Amelogenin is an extracellular matrix protein involved in biomineralization during tooth enamel development. Clinical significance Mutations in the related AMELX gene on the X chromosome cause X-linked amelogenesis imperfecta. References External links Further reading Genes on human chromosome Y Genetics
https://en.wikipedia.org/wiki/At%20Crystal%20Palace
At Crystal Palace is the second studio album by the band Erase Errata, released in 2003. Track listing "Driving Test – 1:39 "Ca. Viewing" – 2:53 "Go to Sleep" – 1:56 "Retreat! The Most Familiar" – 2:25 "Surprise, It's Easter" – 1:33 "Let's Be Active C/O Club Hott" – 2:52 "Flippy Flop" – :56 "Owls" – 2:20 "Ease on Over" – 1:52 "The White Horse Is Bucking" – 1:20 "A Thief Detests the Criminal, Elements of the Ruling Class" – 2:11 "Harvester" – 1:22 "Matter No Medley" – 4:07 Personnel Jenny Hoyston - Vocals, Trumpet Ellie Erickson - Bass Bianca Sparta - Drums Sara Jaffe - Guitar Maya - Recorder References 2003 albums Erase Errata albums Queercore albums Blast First albums Avant-pop albums No wave albums Punk rock albums by American artists
https://en.wikipedia.org/wiki/List%20of%20ghost%20towns%20in%20California
This is an incomplete list of ghost towns on California. Classification Barren site Sites no longer in existence Sites that have been destroyed Covered with water Reverted to pasture May have a few difficult to find foundations/footings at most Neglected site Only rubble left Roofless building ruins Buildings or houses still standing, but majority are roofless Abandoned site Building or houses still standing Buildings and houses all abandoned No population, except caretaker Site no longer in existence except for one or two buildings, for example old church, grocery store Semi abandoned site Building or houses still standing Buildings and houses largely abandoned few residents many abandoned buildings Small population Historic community Building or houses still standing Still a busy community Smaller than its boom years Population has decreased dramatically, to one fifth or less. List Fresno Gallery References Calif Ghost town Tourist attractions in California Ghost towns in California
https://en.wikipedia.org/wiki/List%20of%20ghost%20towns%20in%20Texas
Classification Barren site Sites no longer in existence Sites that have been destroyed Submerged Reverted to pasture May have a few difficult-to-find foundations/footings at most Neglected site Only rubble left All buildings uninhabited Roofless building ruins Some buildings or houses still standing Abandoned site Buildings or houses still standing Buildings and houses all abandoned No population, except caretaker Site no longer in existence except for one or two buildings (for example old church, grocery store) Semi-abandoned site Building or houses still standing Buildings and houses largely abandoned Fewer than 50 residents Many abandoned buildings Small population Historic community Building or houses still standing Still a busy community Smaller than its boom years Population has decreased dramatically, to one fifth or less May now be census designated place May have been Absorbed by extant entity List Images References Additional sourcing Texas – GhostTowns.com Texas Ghost Towns Texas Escapes online magazine Ghost Towns of Texas. Norman, OK: University of Oklahoma Press, 1986. Google Books. Retrieved August 19, 2013. External links Texas Ghost towns Ghost towns in Texas
https://en.wikipedia.org/wiki/Novikov%27s%20condition
In probability theory, Novikov's condition is the sufficient condition for a stochastic process which takes the form of the Radon–Nikodym derivative in Girsanov's theorem to be a martingale. If satisfied together with other conditions, Girsanov's theorem may be applied to a Brownian motion stochastic process to change from the original measure to the new measure defined by the Radon–Nikodym derivative. This condition was suggested and proved by Alexander Novikov. There are other results which may be used to show that the Radon–Nikodym derivative is a martingale, such as the more general criterion Kazamaki's condition, however Novikov's condition is the most well-known result. Assume that is a real valued adapted process on the probability space and is an adapted Brownian motion: If the condition is fulfilled then the process is a martingale under the probability measure and the filtration . Here denotes the Doléans-Dade exponential. References External links Martingale theory
https://en.wikipedia.org/wiki/Dihydropteroate
Dihydropteroate is an important intermediate in folate synthesis. It is a pterin created from para-aminobenzoic acid (PABA) by the enzyme dihydropteroate synthase. Bacteriostatic agents such as sulfonamides target dihydropteroate synthetase. The effect of dihydropteroate synthetase inhibition is comparable to that of dihydrofolate reductase inhibition by trimethoprim, another bacteriostatic agent. Combinations of these two drug types, such as the combination trimethoprim/sulfamethoxazole (TMP-SMX]), are commonly used to treat recurrent urinary tract, Shigella, Salmonella, and Pneumocystis jivoreci infections. See also Dihydrofolic acid References Benzoic acids Folates
https://en.wikipedia.org/wiki/Dihydropteroate%20synthase
Dihydropteroate synthase is an enzyme classified under . It produces dihydropteroate in bacteria, but it is not expressed in most eukaryotes including humans. This makes it a useful target for sulfonamide antibiotics, which compete with the PABA precursor. (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + 4-aminobenzoate (PABA) diphosphate + dihydropteroate. All organisms require reduced folate cofactors for the synthesis of a variety of metabolites. Most microorganisms must synthesize folate de novo because they lack the active transport system of higher vertebrate cells that allows these organisms to use dietary folates. Proteins containing this domain include dihydropteroate synthase () as well as a group of methyltransferase enzymes including methyltetrahydrofolate, corrinoid iron-sulphur protein methyltransferase (MeTr) that catalyses a key step in the Wood-Ljungdahl pathway of carbon dioxide fixation. Dihydropteroate synthase () (DHPS) catalyses the condensation of 6-hydroxymethyl-7,8-dihydropteridine pyrophosphate to para-aminobenzoic acid to form 7,8-dihydropteroate. This is the second step in the three-step pathway leading from 6-hydroxymethyl-7,8-dihydropterin to 7,8-dihydrofolate. DHPS is the target of sulfonamides, which are substrate analogues that compete with para-aminobenzoic acid. Bacterial DHPS (gene sul or folP) is a protein of about 275 to 315 amino acid residues that is either chromosomally encoded or found on various antibiotic resis
https://en.wikipedia.org/wiki/Chaff%20%28disambiguation%29
Chaff is dry inedible plant material. Chaff may also refer to: Chaff (countermeasure), a radar countermeasure for aircraft or other targets Chaff algorithm, an algorithm for solving instances of the boolean satisfiability problem Chaffing and winnowing, a method in cryptography to protect a message without encryption Chaff (newspaper), a former students' newspaper of Massey University Students' Association See also "Gumbo Chaff" or "Gombo Chaff", an American song Chaff cutter, a mechanical device for cutting straw or hay
https://en.wikipedia.org/wiki/Local%20independence
Within statistics, Local independence is the underlying assumption of latent variable models. The observed items are conditionally independent of each other given an individual score on the latent variable(s). This means that the latent variable explains why the observed items are related to one another. This can be explained by the following example. Example Local independence can be explained by an example of Lazarsfeld and Henry (1968). Suppose that a sample of 1000 people was asked whether they read journals A and B. Their responses were as follows: One can easily see that the two variables (reading A and reading B) are strongly related, and thus dependent on each other. Readers of A tend to read B more often (52%) than non-readers of A (28%). If reading A and B were independent, then the formula P(A&B) = P(A)×P(B) would hold. But 260/1000 isn't 400/1000 × 500/1000. Thus, reading A and B are statistically dependent on each other. If the analysis is extended to also look at the education level of these people, the following tables are found. Again, if reading A and B were independent, then P(A&B) = P(A)×P(B) would hold separately for each education level. And, in fact, 240/500 = 300/500×400/500 and 20/500 = 100/500×100/500. Thus if a separation is made between people with high and low education backgrounds, there is no dependence between readership of the two journals. That is, reading A and B are independent once educational level is taken into consideration. The educ
https://en.wikipedia.org/wiki/GM%20HydroGen3
HydroGen3 was an Opel hydrogen fuel cell concept vehicle used for testing in 2006. HydroGen3's driving range is the highest of any fuel cell vehicle approved for public roads in Japan. The five seater front-wheel driven prototype is based on the Opel Zafira compact MPV. Technical specifications Fuel storage system: there are two hydrogen storage system used: liquid hydrogen: stainless steel liquefied hydrogen tank, installed ahead of rear axle under rear seat, length/diameter 1000/400 mm, capacity 68 L/4.6 kg, gross weight . compressed hydrogen at 700 bar. Fuel cell unit: 200 individual fuel cells wired in series, voltage 125-200 V, dimensions: 472×251×496 mm, active area: 800 cm2, pressure: 1.5-2.7 bars, output: 94 kW, power density: 1.6 kW/L or 0.94 kW/kg. electric traction system: Three-phase asynchronous electric motor with integrated power electronics and planetary gear, operating voltage: 250-380 V, output: 60 kW, torque: 215 Nm, max. engine rpm: 12000, gear ratio: 8.67:1, gross weight: , dimensions: 4317×1742×1684 mm, vehicle curb weight: 1590 kg (target value), performance: acceleration 0–100 km/h: 16 s, top speed: , operating range: 400 km. See also HydroGen4 List of fuel cell vehicles References External links https://web.archive.org/web/20070210224533/http://www.gm.com/company/gmability/adv_tech/400_fcv/hydrogen3_in_japan_050103.html Fuel cell vehicles HydroGen3
https://en.wikipedia.org/wiki/Fibroin
Fibroin is an insoluble protein present in silk produced by numerous insects, such as the larvae of Bombyx mori, and other moth genera such as Antheraea, Cricula, Samia and Gonometa. Silk in its raw state consists of two main proteins, sericin and fibroin, with a glue-like layer of sericin coating two singular filaments of fibroin called brins. Silk fibroin is considered a β-keratin related to proteins that form hair, skin, nails and connective tissues. The silk worm produces fibroin with three chains, the light, heavy, and the glycoprotein P25. The heavy and light chains are linked by a disulphide bond, and P25 associates with disulphide-linked heavy and light chains by noncovalent interactions. P25 plays an important role in maintaining integrity of the complex. The heavy fibroin protein consists of layers of antiparallel beta sheets. Its primary structure mainly consists of the recurrent amino acid sequence (Gly-Ser-Gly-Ala-Gly-Ala)n. The high glycine (and, to a lesser extent, alanine) content allows for tight packing of the sheets, which contributes to silk's rigid structure and tensile strength. A combination of stiffness and toughness make it a material with applications in several areas, including biomedicine and textile manufacture. Fibroin is known to arrange itself in three structures, called silk I, II, and III. Silk I is the natural form of fibroin, as emitted from the Bombyx mori silk glands. Silk II refers to the arrangement of fibroin molecules in spun sil
https://en.wikipedia.org/wiki/List%20of%20semiconductor%20IP%20core%20vendors
The following is a list of notable vendors in the business of licensing IP cores Analog-to-Digital Converters S3 Group Cadence Design Systems Cosmic Circuits Dolphin Integration Synopsys Broadband modem and error correction Cadence Design Systems CEVA, Inc. IMEC On2 Technologies (through acquisition of Hantro) Synopsys (through acquisition of Virage Logic) Tensilica (now part of Cadence Design Systems) Digital to Analog Converters S3 Group Cadence Design Systems Cosmic Circuits (now part of Cadence Design Systems) Dolphin Integration Digital Signal Processors Synopsys - ARC Tensilica - Xtensa (now part of Cadence Design Systems) DRAM DRAM controllers Actel Altera Arm Barco Silex Cadence Design Systems (through acquisition of Denali Software) Faraday Technology Lattice Semiconductor Rambus Synopsys Xilinx DRAM PHYs Arm Cadence Design Systems (through acquisition of Denali Software) Synopsys (through acquisition of Virage Logic) High-Bandwidth Memory - HBM PHYs eSilicon Rambus Synopsys Hybrid Memory Cube - HMC Controllers Open-Silicon University of Heidelberg Communication IP Network-on-Chip (NoC) / On-Chip Interconnect Arteris IP Arm Bluetooth SW Stack, Link Layer and PHY Arm (through acquisition of Dicentric and Sunrise Micro Devices) Ethernet PHY Arm (through acquisition of Artisan Components) Cadence Design Systems V by One Socionext - HV Series General purpose microprocessors Arm - Arm Cortex and Neove
https://en.wikipedia.org/wiki/Hoshaiah%20Rabbah
Hoshaiah Rabbah or Hoshayya Rabbah (also "Roba", "Berabbi", Hebrew: אושעיא בריבי) was a Amora of the Land of Israel from the first amoraic generation (about 200 CE), compiler of Baraitot explaining the Mishnah-Tosefta. Biography He was closely associated with the successors of Judah ha-Nasi, as was his father with Judah ha-Nasi himself. Hoshaiah's father, Hama, lived in Sepphoris, the residence of Judah ha-Nasi and the seat of the patriarchs. Hoshaiah's yeshivah, too, was for many years located at Sepphoris, where pupils crowded to hear his lectures. Johanan bar Nappaha, one of his greatest disciples, declared that Hoshaiah in his generation was like Rabbi Meir in his: even his colleagues could not always grasp the profundity of his arguments. And the esteem in which Hoshaiah was held by his pupils may be gauged by the statement that, even after Johanan had himself become a great scholar and a famous teacher and no longer needed Hoshaiah's instruction, he continued visiting the master, who in the meantime had grown old and moved his school to Caesarea. Hoshaiah's consideration for others is exemplified in his gracious apology to the blind teacher whom he had engaged for his son, and whom he did not suffer to meet visitors at dinner for fear that he might be embarrassed. Hoshaiah's authority must have been very powerful in his later years, when he successfully resisted the efforts of Gamaliel III, the son of Judah ha-Nasi, to introduce demai into Syria. It is also indicat
https://en.wikipedia.org/wiki/Marangoni%20number
The Marangoni number (Ma) is, as usually defined, the dimensionless number that compares the rate of transport due to Marangoni flows, with the rate of transport of diffusion. The Marangoni effect is flow of a liquid due to gradients in the surface tension of the liquid. Diffusion is of whatever is creating the gradient in the surface tension. Thus as the Marangoni number compares flow and diffusion timescales it is a type of Péclet number. The Marangoni number is defined as: A common example is surface tension gradients caused by temperature gradients. Then the relevant diffusion process is that of thermal energy (heat). Another is surface gradients caused by variations in the concentration of surfactants, where the diffusion is now that of surfactant molecules. The number is named after Italian scientist Carlo Marangoni, although its use dates from the 1950s and it was neither discovered nor used by Carlo Marangoni. The Marangoni number for a simple liquid of viscosity with a surface tension change over a distance parallel to the surface, can be estimated as follows. Note that we assume that is the only length scale in the problem, which in practice implies that the liquid be at least deep. The transport rate is usually estimated using the equations of Stokes flow, where the fluid velocity is obtained by equating the stress gradient to the viscous dissipation. A surface tension is a force per unit length, so the resulting stress must scale as , while the viscous st
https://en.wikipedia.org/wiki/Heinz%20Zemanek
Heinz Zemanek (actually Heinrich Josef Zemanek) (1 January 1920 – 16 July 2014) was an Austrian computer pioneer who led the development, from 1954 to 1958, of one of the first complete transistorised computers on the European continent. The computer was nicknamed Mailüfterl — Viennese for "May breeze" — in reference to Whirlwind, a computer developed at MIT between 1945 and 1951. Life Heinz Zemanek went to a secondary school in Vienna and earned his Matura in 1937. He then started to study at the University of Vienna. In 1940, Zemanek was drafted into the Wehrmacht, where he served in a "communication unit" and also as a teacher in an Intelligence Service School. Returning to studying radar technology he earned his Diplom in 1944 with the help of University of Stuttgart professor Richard Feldtkeller (1901–1981). After the war Zemanek worked as an assistant at the university and earned his PhD in 1951 about timesharing methods in multiplex telegraphy. In 1952 he completed the URR1 (Universal Relais Rechner 1, i.e., Universal Relay Computer 1). He died at the age of 94 on 16 July 2014. The Vienna Lab The IBM Laboratory Vienna, also known as the Vienna Lab, was founded in 1961 as a department of the IBM Laboratory in Böblingen, Germany, with Professor Zemanek as its first manager. Zemanek remained with the Vienna Lab until 1976, when he was appointed an IBM Fellow. He was crucial in the creation of the formal definition of the programming language PL/I. For several years, Z
https://en.wikipedia.org/wiki/Angular%20velocity%20tensor
The angular velocity tensor is a skew-symmetric matrix defined by: The scalar elements above correspond to the angular velocity vector components . This is an infinitesimal rotation matrix. The linear mapping Ω acts as a cross product : where is a position vector. When multiplied by a time difference, it results in the angular displacement tensor. Calculation of angular velocity tensor of a rotating frame A vector undergoing uniform circular motion around a fixed axis satisfies: Let be the orientation matrix of a frame, whose columns , , and are the moving orthonormal coordinate vectors of the frame. We can obtain the angular velocity tensor Ω(t) of A(t) as follows: The angular velocity must be the same for each of the column vectors , so we have: which holds even if A(t) does not rotate uniformly. Therefore, the angular velocity tensor is: since the inverse of an orthogonal matrix is its transpose . Properties In general, the angular velocity in an n-dimensional space is the time derivative of the angular displacement tensor, which is a second rank skew-symmetric tensor. This tensor Ω will have independent components, which is the dimension of the Lie algebra of the Lie group of rotations of an n-dimensional inner product space. Duality with respect to the velocity vector In three dimensions, angular velocity can be represented by a pseudovector because second rank tensors are dual to pseudovectors in three dimensions. Since the angular vel
https://en.wikipedia.org/wiki/Intersection%20of%20a%20polyhedron%20with%20a%20line
In computational geometry, the problem of computing the intersection of a polyhedron with a line has important applications in computer graphics, optimization, and even in some Monte Carlo methods. It can be viewed as a three-dimensional version of the line clipping problem. If the polyhedron is given as the intersection of a finite number of halfspaces, then one may partition the halfspaces into three subsets: the ones that include only one infinite end of the line, the ones that include the other end, and the ones that include both ends. The halfspaces that include both ends must be parallel to the given line, and do not contribute to the solution. Each of the other two subsets (if it is non-empty) contributes a single endpoint to the intersection, which may be found by intersecting the line with each of the halfplane boundary planes and choosing the intersection point that is closest to the end of the line contained by the halfspaces in the subset. This method, a variant of the Cyrus–Beck algorithm, takes time linear in the number of face planes of the input polyhedron. Alternatively, by testing the line against each of the polygonal facets of the given polyhedron, it is possible to stop the search early when a facet pierced by the line is found. If a single polyhedron is to be intersected with many lines, it is possible to preprocess the polyhedron into a hierarchical data structure in such a way that intersections with each query line can be determined in logarithmic
https://en.wikipedia.org/wiki/Hypoelliptic%20operator
In the theory of partial differential equations, a partial differential operator defined on an open subset is called hypoelliptic if for every distribution defined on an open subset such that is (smooth), must also be . If this assertion holds with replaced by real-analytic, then is said to be analytically hypoelliptic. Every elliptic operator with coefficients is hypoelliptic. In particular, the Laplacian is an example of a hypoelliptic operator (the Laplacian is also analytically hypoelliptic). In addition, the operator for the heat equation () (where ) is hypoelliptic but not elliptic. However, the operator for the wave equation () (where ) is not hypoelliptic. References Partial differential equations Differential operators
https://en.wikipedia.org/wiki/List%20of%20Wolverhampton%20Wanderers%20F.C.%20records%20and%20statistics
Wolverhampton Wanderers Football Club is an English football club based in Wolverhampton. The club was founded as St Luke's in 1877, soon becoming Wolverhampton Wanderers, before being a founder member of the Football League in 1888. Since that time, the club has played in all four professional divisions of the English football pyramid, and been champions of all these levels. They have also been involved in European football, having been one of the first English clubs to enter the European Cup, as well as reaching the final of the first staging of the UEFA Cup. This list encompasses all honours won by Wolverhampton Wanderers and records set by the club, their managers and their players. The player records section includes details of the club's leading goalscorers and those who have made most appearances in first-team competitions, as well as transfer fee records paid and received by the club. A list of streaks recording all elements of the game (wins, losses, clean sheets, etc.) is also presented. Honours In the all-time top flight league table since the league's inception in 1888, Wolves sit in the top fifteen, in terms of all-time English first level league position. Alternatively, they sit in the top four, behind only Manchester United, Liverpool and Arsenal in terms of all-time league position from points gained at any level of English professional football. Cumulatively, they are the joint 11th most successful club in domestic English football history, tied with Nott
https://en.wikipedia.org/wiki/Tris%28bipyridine%29ruthenium%28II%29%20chloride
Tris(bipyridine)ruthenium(II) chloride is the chloride salt coordination complex with the formula [Ru(bpy)3]2+ 2Cl−. This polypyridine complex is a red crystalline salt obtained as the hexahydrate, although all of the properties of interest are in the cation [Ru(bpy)3]2+, which has received much attention because of its distinctive optical properties. The chlorides can be replaced with other anions, such as PF6−. Synthesis and structure This salt is prepared by treating an aqueous solution of ruthenium trichloride with 2,2'-bipyridine. In this conversion, Ru(III) is reduced to Ru(II), and hypophosphorous acid is typically added as a reducing agent. [Ru(bpy)3]2+ is octahedral, containing a central low spin d6 Ru(II) ion and three bidentate bpy ligands. The Ru-N distances are 2.053(2), shorter than the Ru-N distances for [Ru(bpy)3]3+. The complex is chiral, with D3 symmetry. It has been resolved into its enantiomers. In its lowest lying triplet excited state the molecule is thought to attain lower C2 symmetry, as the excited electron is localized primarily on a single bipyridyl ligand. Photochemistry of [Ru(bpy)3]2+ [Ru(bpy)3]2+ absorbs ultraviolet and visible light. Aqueous solutions of [Ru(bpy)3]Cl2 are orange due to a strong MLCT absorption at 452 ± 3 nm (extinction coefficient of 14,600 M−1cm−1). Further absorption bands are found at 285 nm corresponding to ligand centered π*← π transitions and a weak transition around 350 nm (d-d transition). Light absorption re
https://en.wikipedia.org/wiki/Pandemic%20severity%20index
The pandemic severity index (PSI) was a proposed classification scale for reporting the severity of influenza pandemics in the United States. The PSI was accompanied by a set of guidelines intended to help communicate appropriate actions for communities to follow in potential pandemic situations. Released by the United States Department of Health and Human Services (HHS) on February 1, 2007, the PSI was designed to resemble the Saffir-Simpson Hurricane Scale classification scheme. The index was replaced by the Pandemic Severity Assessment Framework in 2014, which uses quadrants based on transmissibility and clinical severity rather than a linear scale. Development The PSI was developed by the Centers for Disease Control and Prevention (CDC) as a new pandemic influenza planning tool for use by states, communities, businesses and schools, as part of a drive to provide more specific community-level prevention measures. Although designed for domestic implementation, the HHS has not ruled out sharing the index and guidelines with interested international parties. The index and guidelines were developed by applying principles of epidemiology to data from the history of the last three major flu pandemics and seasonal flu transmission, mathematical models, and input from experts and citizen focus groups. Many "tried and true" practices were combined in a more structured manner: Context During the onset of a growing pandemic, local communities cannot rely upon widespread availabil
https://en.wikipedia.org/wiki/Limonin
Limonin is a limonoid, and a bitter, white, crystalline substance found in citrus and other plants. It is also known as limonoate D-ring-lactone and limonoic acid di-delta-lactone. Chemically, it is a member of the class of compounds known as furanolactones. Sources Limonin is enriched in citrus fruits and is often found at higher concentrations in seeds, for example orange and lemon seeds. Presence in citrus products Limonin and other limonoid compounds contribute to the bitter taste of some citrus food products. Researchers have proposed removal of limonoids from orange juice and other products (known as "debittering") through the use of polymeric films. Research Limonin is under basic research to assess its possible biological properties. References External links "Citrus Compound: ready to help your body!" (Agricultural Research Service, USDA) Epoxides 3-Furyl compounds Delta-lactones Terpenes and terpenoids
https://en.wikipedia.org/wiki/Forward%E2%80%93backward%20algorithm
The forward–backward algorithm is an inference algorithm for hidden Markov models which computes the posterior marginals of all hidden state variables given a sequence of observations/emissions , i.e. it computes, for all hidden state variables , the distribution . This inference task is usually called smoothing. The algorithm makes use of the principle of dynamic programming to efficiently compute the values that are required to obtain the posterior marginal distributions in two passes. The first pass goes forward in time while the second goes backward in time; hence the name forward–backward algorithm. The term forward–backward algorithm is also used to refer to any algorithm belonging to the general class of algorithms that operate on sequence models in a forward–backward manner. In this sense, the descriptions in the remainder of this article refer only to one specific instance of this class. Overview In the first pass, the forward–backward algorithm computes a set of forward probabilities which provide, for all , the probability of ending up in any particular state given the first observations in the sequence, i.e. . In the second pass, the algorithm computes a set of backward probabilities which provide the probability of observing the remaining observations given any starting point , i.e. . These two sets of probability distributions can then be combined to obtain the distribution over states at any specific point in time given the entire observation sequence: T
https://en.wikipedia.org/wiki/Carl%20Eckart
Carl Henry Eckart (May 4, 1902 – October 23, 1973) was an American physicist, physical oceanographer, geophysicist, and administrator. He co-developed the Wigner–Eckart theorem and is also known for the Eckart conditions in quantum mechanics, and the Eckart–Young theorem in linear algebra. Early life Eckart was born in St. Louis, Missouri. He began college in 1919 at Washington University in St. Louis where he received his B.S. and M.S. degrees with a major in engineering. However, due to Arthur Holly Compton, a physics faculty member and later Chancellor, Eckart was influenced to continue his education in physics at Princeton, where he went in 1923 on an Edison Lamp Works Research Fellowship. Eckart was awarded his Ph.D. in 1925. During his graduate studies, Eckart co-authored a paper with Karl Compton, brother of Arthur Compton on low-voltage arcs, particularly the oscillatory phenomena arising in the diffusion of electrons against low-voltage fields. He continued this line of work after receipt of his Ph.D. on a National Research Council Fellowship at the California Institute of Technology (Caltech) during the period 1925 to 1927. Max Born, director of the Institute for Theoretical Physics at the University of Göttingen and co-developer of the matrix mechanics formulation of quantum mechanics with Werner Heisenberg, came to Caltech in the winter of 1925 and gave a lecture on his work. Born’s lecture gave Eckart the impetus to investigate the possible general operato
https://en.wikipedia.org/wiki/Mayo%E2%80%93Lewis%20equation
The Mayo–Lewis equation or copolymer equation in polymer chemistry describes the distribution of monomers in a copolymer. It was proposed by Frank R. Mayo and Frederick M. Lewis. The equation considers a monomer mix of two components and and the four different reactions that can take place at the reactive chain end terminating in either monomer ( and ) with their reaction rate constants : The reactivity ratio for each propagating chain end is defined as the ratio of the rate constant for addition of a monomer of the species already at the chain end to the rate constant for addition of the other monomer. The copolymer equation is then: with the concentrations of the components in square brackets. The equation gives the relative instantaneous rates of incorporation of the two monomers. Equation derivation Monomer 1 is consumed with reaction rate: with the concentration of all the active chains terminating in monomer 1, summed over chain lengths. is defined similarly for monomer 2. Likewise the rate of disappearance for monomer 2 is: Division of both equations by followed by division of the first equation by the second yields: The ratio of active center concentrations can be found using the steady state approximation, meaning that the concentration of each type of active center remains constant. The rate of formation of active centers of monomer 1 () is equal to the rate of their destruction () so that or Substituting into the ratio of monomer consumption rat
https://en.wikipedia.org/wiki/Nucleic%20acid%20thermodynamics
Nucleic acid thermodynamics is the study of how temperature affects the nucleic acid structure of double-stranded DNA (dsDNA). The melting temperature (Tm) is defined as the temperature at which half of the DNA strands are in the random coil or single-stranded (ssDNA) state. Tm depends on the length of the DNA molecule and its specific nucleotide sequence. DNA, when in a state where its two strands are dissociated (i.e., the dsDNA molecule exists as two independent strands), is referred to as having been denatured by the high temperature. Concepts Hybridization Hybridization is the process of establishing a non-covalent, sequence-specific interaction between two or more complementary strands of nucleic acids into a single complex, which in the case of two strands is referred to as a duplex. Oligonucleotides, DNA, or RNA will bind to their complement under normal conditions, so two perfectly complementary strands will bind to each other readily. In order to reduce the diversity and obtain the most energetically preferred complexes, a technique called annealing is used in laboratory practice. However, due to the different molecular geometries of the nucleotides, a single inconsistency between the two strands will make binding between them less energetically favorable. Measuring the effects of base incompatibility by quantifying the temperature at which two strands anneal can provide information as to the similarity in base sequence between the two strands being annealed. The
https://en.wikipedia.org/wiki/Synovectomy
Synovectomy is a procedure where the synovial tissue surrounding a joint is removed. This procedure is typically recommended to provide relief from a condition in which the synovial membrane or the joint lining becomes inflamed and irritated and is not controlled by medication alone. If arthritis (inflammation of the joint) is not controlled, it can lead to irreversible joint damage. The synovial membrane or "synovium" encloses each joint and also secretes a lubricating fluid that allows different joint motions such as rolling, folding and stretching. When the synovium becomes inflamed or irritated, it increases fluid production, resulting in warmth, tenderness, and swelling in and around the joint. A synovectomy is a procedure often suggested for those with rheumatoid arthritis or other forms of inflammatory arthritis when non-operative treatments have failed. This procedure can be performed in several ways, namely surgical synovectomy, chemical synovectomy and radiological. The surgical procedure can be performed arthroscopically or by opening the joint to remove the synovial tissue surrounding the joint that has become inflamed and swollen. Chemical Synovectomy involves an intraarticular osmic acid injection with the objective to debulk or reduce the inflammatory synovial mass. Indications Synovectomy is indicated in following conditions: Inflammatory arthritis: rheumatoid arthritis, hemophilia, chondromatosis Synovial tumors: pigmented villonodular synovitis Septic
https://en.wikipedia.org/wiki/Ticket%20Crystals
Ticket Crystals is the seventh studio album by Bardo Pond. It was released on June 6, 2006. The album features a cover of The Beatles' song "Cry Baby Cry". Reception Like its predecessors, the album received largely positive reviews from critics. Fred Thomas of Allmusic found the "gentler" album to be "drenched in dubby reverb and delay, tucking its more menacing tones in layers of starlit musical wandering and resonating the most on subdued numbers like the sprawling "Isle" and a hazy reading of the Beatles' "Cry Baby Cry."" Jennifer Kelly of Popmatters considered the music to be "beautiful and [...] disturbing" in its combinations of "freak folk, drone and psychedelic metal." Gigwise hailed it as a "damn loud and a damn fine album", while Eric Hill of Exclaim! called it the band's best album since Lapsed. More mixed reviews came from Cameron Macdonald of Stylus who found the band to be stylistically stagnating with the album, and criticized the closing track "Montana Sacra II" as being "[a] great opportunity squandered." In an otherwise positive review, Christian Maiwald of Ox-Fanzine found Sollenberger's vocals to be occasionally distracting & criticized the songs as being too short. Pitchfork'''s Mia Lily Clarke criticized the "overwhelming" use of flute & some of its "cloying prog mayhem." A negative review came from Spanish magazine Mondosonoro'', which scored the album a 1 out of 10. Track listing "Destroying Angel" – 9:38 "Isle" – 11:13 "Lost Word" – 6:29 "Cry Bab
https://en.wikipedia.org/wiki/Kasos%20Island%20Public%20Airport
Kasos Island Public Airport is an airport in Kasos, Greece. Airlines and destinations The following airlines operate regular scheduled and charter flights at Kasos Island Airport: Statistics See also Transport in Greece References External links Airports in Greece Dodecanese Buildings and structures in the South Aegean
https://en.wikipedia.org/wiki/Shock%20%28fluid%20dynamics%29
Shock is an abrupt discontinuity in the flow field and it occurs in flows when the local flow speed exceeds the local sound speed. More specifically, it is a flow whose Mach number exceeds 1. Explanation of phenomena Shock is formed due to coalescence of various small pressure pulses. Sound waves are pressure waves and it is at the speed of the sound wave the disturbances are communicated in the medium. When an object is moving in a flow field the object sends out disturbances which propagate at the speed of sound and adjusts the remaining flow field accordingly. However, if the object itself happens to travel at speed greater than sound, then the disturbances created by the object would not have traveled and communicated to the rest of the flow field and this results in an abrupt change of property, which is termed as shock in gas dynamics terminology. Shocks are characterized by discontinuous changes in flow properties such as velocity, pressure, temperature, etc. Typically, shock thickness is of a few mean free paths (of the order of 10−8 m). Shocks are irreversible occurrences in supersonic flows (i.e. the entropy increases). Normal shock formulas Where, the index 1 refers to upstream properties, and the index 2 refers to down stream properties. The subscript 0 refers to total or stagnation properties. T is temperature, M is the mach number, P is pressure, ρ is density, and γ is the ratio of specific heats. See also Mach number Sound barrier supersonic flow Flui
https://en.wikipedia.org/wiki/Edna%20B.%20Foa
Edna Foa (born 1937, Haifa) is an Israeli professor of clinical psychology at the University of Pennsylvania, where she serves as the director of the Center for the Treatment and Study of Anxiety. Foa is an internationally renowned authority in the field of psychopathology and treatment of anxiety. She approaches the understanding and treatment of mental disorders from a cognitive-behavioral perspective. Academic career Foa was born to a Jewish family and earned her BA in psychology and literature from Bar Ilan University in 1962, and her MA in clinical psychology from the University of Illinois in 1970. In that same year she completed her PhD in clinical psychology and personality at the University of Missouri. Her research, aimed at determining causes and treatments of anxiety disorders, has been highly influential. Foa is an expert in post-traumatic stress disorders (PTSD) and obsessive-compulsive disorder (OCD). The program she has developed for rape survivors is considered to be one of the most effective therapies for PTSD. She has published several books and over 200 articles and book chapters, has lectured extensively around the world, and was the chair of the PTSD work group of the DSM-IV. Foa's research interests are development and evaluation of cognitive-behavioral treatment for obsessive compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and social anxiety disorder (SAD); experimental psychopathology of anxiety disorders, especially post-traumati
https://en.wikipedia.org/wiki/Calyculin
Calyculins are natural products originally isolated from the marine sponge Discodermia calyx. Calyculins have proven to be strong serine/threonine protein phosphatase inhibitors and based on this property, calyculins might be potential tumor-promoting agents. References Organophosphates Nitriles Spiro compounds
https://en.wikipedia.org/wiki/WOKW
WOKW is a commercially licensed FM radio station. It operates on the federally assigned frequency of 102.9 MHz at an effective radiated power of 3,000 watts. WOKW is licensed to Curwensville, Pennsylvania, but maintains studios and offices in Lawrence Township, just outside of Clearfield. History WOKW signed on the air on August 1, 1989, at 10:29 a.m. That exact time and day was chosen as they numerically reflected the new station's frequency of 102.9. The station was initially assigned the call letters WWWS, but those were changed shortly before the station went on the air. The station has been owned by Raymark Broadcasting since it first went on the air and had maintained the same adult contemporary format through ABC/SMN/Westwood One until September 30, 2019. On October 1, RayMark Broadcasting severed their 36-year relationship with WestWood One and took control of programming the music. The station now includes over fifty years of popular music, both current and past artists, with rock album cuts, B-sides, and forgotten classics added in after 5 PM and during weekends. Prior to the existence of this station, WOKW was assigned to the station now known as WIII in Cortland, New York. In the early 1980s that version of WOKW was known as OK100 in Cortland. They also broadcast the same show in Ithaca, NY on 108 (ad spot: OK100, Ithaca 108). WOKW was for much its history the sister station of AM 1160 WCCS, located in Homer City, Pennsylvania. WCCS first went on the air
https://en.wikipedia.org/wiki/KRI%20Leuser
The KRI Leuser (924) is an Indonesian naval vessel of the Soputan-class ocean-going tugs. Leusers name is derived from Mount Leuser with its Leuser Ecosystem, the highest mountain in Aceh province. The ship is a seagoing tugs, the second vessel of the Soputan class designed by South Korean company, Daesun Shipbuilding and built under license by PT. Dok dan Perkapalan Kodja Bahari (DKB) in Jakarta, Indonesia. The ship was launched on 22 August 2002. Service history The Leuser was deployed to aid in the search for the missing Adam Air Flight 574 in January 2007. References Tugboats of the Indonesian Navy Naval ships of Indonesia 2002 ships
https://en.wikipedia.org/wiki/Multilevel%20queue
Multi-level queueing, used at least since the late 1950s/early 1960s, is a queue with a predefined number of levels. Items get assigned to a particular level at insert (using some predefined algorithm), and thus cannot be moved to another level (unlike in the multilevel feedback queue). Items get removed from the queue by removing all items from a level, and then moving to the next. If an item is added to a level above, the "fetching" restarts from there. Each level of the queue is free to use its own scheduling, thus adding greater flexibility than merely having multiple levels in a queue. Process Scheduling Multi-level queue scheduling algorithm is used in scenarios where the processes can be classified into groups based on property like process type, CPU time, IO access, memory size, etc. One general classification of the processes is foreground processes and background processes. In a multi-level queue scheduling algorithm, there will be 'n' number of queues, where 'n' is the number of groups the processes are classified into. Each queue will be assigned a priority and will have its own scheduling algorithm like Round-robin scheduling or FCFS. For the process in a queue to execute, all the queues of priority higher than it should be empty, meaning the process in those high priority queues should have completed its execution. In this scheduling algorithm, once assigned to a queue, the process will not move to any other queues. Consider the following table with the arri
https://en.wikipedia.org/wiki/Cybele%20Andrianou
Cybele Andrianou (; 13 July 1888 – 26 May 1978), also known by her stage name Cybele (), was a Greek actress. She was born on 13 July 1888 to an unmarried couple in Smyrna and spent the first two years of her life in an Athens orphanage. At the age of two-and-a-half, she was adopted by Anastasis and Maria Andrianou. The family of a famous Athenian lawyer of the time, who had recently lost their only child, helped Cybele's adoptive parents financially. In 1901, at the age of 13, she received her first award for her stage performance. There is a statue honouring her in Pagrati Grove, Athens. Career Cybele was one of the main actresses of Nea Skini from 1901 to 1906. There, she had the chance to perform the only roles of her life based on ancient Greek tragedy: Euripides' Alcestis and Sophocles' Antigone. She later became known for her performances in plays of Leo Tolstoy, Carlo Goldoni and Henrik Ibsen. In 1908, she worked for the first time with Gregorios Xenopoulos, who wrote her the theatric play The Red Rock (Ο Κόκκινος Βράχος), based his short novel written of the same name. The play was of huge success, and was repeated by Cybele's theatrical group for many years to come. Xenopoulos continued to write her at least one play a year, until 1925. Cybele also worked with Pantelis Horn (the father of Dimitris Horn) from 1910 to 1934. In 1932, she joined forces with Marika Kotopouli, her "stage enemy", in order to compete the newly founded National Theater of Greece. After t
https://en.wikipedia.org/wiki/Fauna%20of%20Barbados
The fauna of Barbados comprises all the animal species inhabiting the island of Barbados and its surrounding waters. Barbados has less biodiversity than the other Antilles. Human activities are responsible for the change in the composition of the fauna, in particular, the replacement of native species. Species that are able to adapt to human presence have survived. Origin of Barbadian Fauna The island of Barbados was formed by tectonic uplift and is younger than the surrounding lesser Antillean islands, primarily of volcanic origin. Avian colonization has therefore occurred recently relative to the geological age of the island, accounting in part for the lack of endemic species relative to neighboring islands. Species capable of crossing the sea barrier by flight enjoyed a comparative advantage, helping to explain why avian species are more numerous than other animal groups, such as mammals. In addition to the natural colonization of the island by animals, humans have contributed to the faunal composition of the island through species introductions (intentional and accidental). Mammals Few mammals live on the island, composed almost entirely of introduced species. The Norway rat (Rattus norvegicus), house mouse (Mus musculus), European hare (Lepus europaeus), small Indian mongoose (Urva auropunctata), and green monkey (Cercopithecus aethiops sabaeus) are the most notable examples. Pigs were introduced by the Portuguese in 1563 as a future food source; the introduction wa
https://en.wikipedia.org/wiki/NASBA%20%28molecular%20biology%29
Nucleic acid sequence-based amplification, commonly referred to as NASBA, is a method in molecular biology which is used to produce multiple copies of single stranded RNA. NASBA is a two-step process that takes RNA and anneals specially designed primers, then utilizes an enzyme cocktail to amplify it. Background Nucleic acid amplification is a technique used to produce several copies of a specific segment of RNA/DNA. Amplified RNA and DNA can be used for a variety of applications, such as genotyping, sequencing, and detection of bacteria or viruses. There are two different types of amplification, non-isothermal and isothermal. Non-isothermal amplification produces multiple copies of RNA/DNA through reiterative cycling between different temperatures. Isothermal amplification produces multiple copies of RNA/DNA at a constant reaction temperature. NASBA takes single stranded RNA, anneals primers to it at 65°C, and then amplifies it at 41°C to produce multiple copies of single stranded RNA. In order for successful amplification to occur, an enzyme cocktail containing, Avian Myeloblastosis Reverse Transcriptase (AMV-RT), RNase H, and RNA polymerase is used. AMV-RT synthesizes a complementary DNA strand (cDNA) from the RNA template once the primer is annealed. RNase H then degrades the RNA template and the other primer binds to the cDNA to form double stranded DNA, which RNA polymerase uses to synthesize copies of RNA. One key aspect of NASBA is that the starting material and end
https://en.wikipedia.org/wiki/Dying%20Sun
Dying Sun is the second full-length studio album by the French death metal band Yyrkoon. Track listing "Idols Are Burning" – 0:30 "Crystal Light" – 3:42 "Flight of the Titan" – 5:00 "The Clans" – 3:51 "Thrash-em All" – 6:27 "Gods of Silver" – 2:58 "Stolen Souls" – 5:00 "Screamer" – 6:25 "Back to the Cave" – 4:35 "Dying Sun" – 1:56 Personnel Stéphane Souteryand - vocals, guitars François Falempin - guitars Geoffrey Gautier - keyboards Victorien Vilchez - bass Laurent Harrouart - drums References 2004 albums Yyrkoon (band) albums
https://en.wikipedia.org/wiki/Dynamic%20problem%20%28algorithms%29
Dynamic problems in computational complexity theory are problems stated in terms of changing input data. In its most general form, a problem in this category is usually stated as follows: Given a class of input objects, find efficient algorithms and data structures to answer a certain query about a set of input objects each time the input data is modified, i.e., objects are inserted or deleted. Problems in this class have the following measures of complexity: Space the amount of memory space required to store the data structure; Initialization time time required for the initial construction of the data structure; Insertion time time required for the update of the data structure when one more input element is added; Deletion time time required for the update of the data structure when an input element is deleted; Query time time required to answer a query; Other operations specific to the problem in question The overall set of computations for a dynamic problem is called a dynamic algorithm. Many algorithmic problems stated in terms of fixed input data (called static problems in this context and solved by static algorithms) have meaningful dynamic versions. Special cases Incremental algorithms, or online algorithms, are algorithms in which only additions of elements are allowed, possibly starting from empty/trivial input data. Decremental algorithms are algorithms in which only deletions of elements are allowed, starting with the initialization of a full data struc
https://en.wikipedia.org/wiki/Magnetic%20Resonance%20Imaging%20%28journal%29
Magnetic Resonance Imaging is a peer-reviewed scientific journal published by Elsevier, encompassing biology, physics, and clinical science as they relate to the development and use of magnetic resonance imaging technology. Magnetic Resonance Imaging was established in 1982 and the current editor-in-chief is John C. Gore. The journal produces 10 issues per year. External links Elsevier academic journals Radiology and medical imaging journals Academic journals established in 1982 English-language journals 10 times per year journals
https://en.wikipedia.org/wiki/AOR%20%28company%29
AOR, Ltd. (Authority on Radio Communications, Ltd.) is a Japanese based manufacturer of radio equipment, including transceivers, scanners, antennas and frequency monitors. Established in 1977 when two radio amateurs decided to go professional. Based in Tokyo, Japan, they also have offices in the United Kingdom and the United States, and manufacturing facilities in Japan and the United Kingdom. External links Official Site AOR UK AOR rigs Complete list of AOR radios Electronics companies of Japan Amateur radio companies Companies based in Tokyo Electronics companies established in 1977 Japanese brands Japanese companies established in 1977
https://en.wikipedia.org/wiki/Gr%C3%ADmsey%20Airport
Grímsey Airport ( ) is an airport serving Grímsey, a small island north of Iceland. Airlines and destinations Statistics Passengers and movements See also Transport in Iceland List of airports in Iceland Notes References External links OpenStreetMap - Grímsey OurAirports - Grímsey Airports in Iceland Akureyri
https://en.wikipedia.org/wiki/Vopnafj%C3%B6r%C3%B0ur%20Airport
Vopnafjörður Airport ( ) is an airport serving the village of Vopnafjörður, in the Eastern Region (Austurland) of Iceland. Airlines and destinations Statistics Passengers and movements Notes References External links Official online guide to Vopnafjordur Airports in Iceland
https://en.wikipedia.org/wiki/Kathryn%20Paterson
Kathryn Mary Paterson (17 October 1962 – 20 September 1999) was the ninth Chief Censor of New Zealand and a Director of Australia's Office of Film and Literature Classification. Biography Paterson was raised in the sea-side town of Umina, north of Sydney, Australia, the daughter of June, a teacher, and Phil Paterson, a pharmacist. Paterson obtained an honours degree in psychology from Macquarie University in 1991. Between 1984 and 1993, she was a senior researcher at the Australian Broadcasting Tribunal (a predecessor of the Australian Communications and Media Authority), a member of the Australian Film Censorship Board and manager of the information unit of the Office of Film and Literature Classification (Australia). Paterson became Chief Censor of New Zealand in 1994. She was New Zealand's ninth Chief Censor, and the first appointed under the new Films, Videos, and Publications Classification Act 1993. This Act gave the Office of Film and Literature Classification jurisdiction to classify a broader range of publications than was possessed by her predecessor as Chief Censor, Jane Wrightson, whose jurisdiction was limited to the classification of films for public exhibition. When she was appointed Chief Censor, the opposition women's affairs spokesperson Elizabeth Tennet MP raised fears that Paterson would import Australian "macho cultural imperialism" into New Zealand. In December 1998, Paterson returned to Sydney to become director of the Australian Office of Film an
https://en.wikipedia.org/wiki/Carleman%27s%20inequality
Carleman's inequality is an inequality in mathematics, named after Torsten Carleman, who proved it in 1923 and used it to prove the Denjoy–Carleman theorem on quasi-analytic classes. Statement Let be a sequence of non-negative real numbers, then The constant (euler number) in the inequality is optimal, that is, the inequality does not always hold if is replaced by a smaller number. The inequality is strict (it holds with "<" instead of "≤") if some element in the sequence is non-zero. Integral version Carleman's inequality has an integral version, which states that for any f ≥ 0. Carleson's inequality A generalisation, due to Lennart Carleson, states the following: for any convex function g with g(0) = 0, and for any -1 < p < ∞, Carleman's inequality follows from the case p = 0. Proof An elementary proof is sketched below. From the inequality of arithmetic and geometric means applied to the numbers where MG stands for geometric mean, and MA — for arithmetic mean. The Stirling-type inequality applied to implies for all Therefore, whence proving the inequality. Moreover, the inequality of arithmetic and geometric means of non-negative numbers is known to be an equality if and only if all the numbers coincide, that is, in the present case, if and only if for . As a consequence, Carleman's inequality is never an equality for a convergent series, unless all vanish, just because the harmonic series is divergent. One can also prove Carleman's inequali
https://en.wikipedia.org/wiki/CRAL-TRIO%20domain
CRAL-TRIO domain is a protein structural domain that binds small lipophilic molecules. This domain is named after cellular retinaldehyde-binding protein (CRALBP) and TRIO guanine exchange factor. CRALB protein carries 11-cis-retinol or 11-cis-retinaldehyde. It modulates interaction of retinoids with visual cycle enzymes. TRIO is involved in coordinating actin remodeling, which is necessary for cell migration and growth. Other members of the family are alpha-tocopherol transfer protein and phosphatidylinositol-transfer protein (Sec14). They transport their substrates (alpha-tocopherol and phosphatidylinositol or phosphatidylcholine, respectively) between different intracellular membranes. Family also include a guanine nucleotide exchange factor that may function as an effector of RAC1 small G-protein. The N-terminal domain of yeast ECM25 protein has been identified as containing a lipid binding CRAL-TRIO domain. Structure The Sec14 protein was the first CRAL-TRIO domain for which the structure was determined. The structure contains several alpha helices as well as a beta sheet composed of 6 strands. Strands 2,3,4 and 5 form a parallel beta sheet with strands 1 and 6 being anti-parallel. The structure also identified a hydrophobic binding pocket for lipid binding. Human proteins containing this domain C20orf121; MOSPD2; PTPN9; RLBP1; RLBP1L1; RLBP1L2; SEC14L1; SEC14L2; SEC14L3; SEC14L4; TTPA; References External links - Calculated spatial posit
https://en.wikipedia.org/wiki/Sterol%20carrier%20protein
Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer steroids and probably also phospholipids and gangliosides between cellular membranes. These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from Thermus thermophilus. This domain is involved in binding sterols. The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipids. Human proteins containing this domain HSD17B4; HSDL2; SCP2; STOML1; See also Steroidogenic acute regulatory protein and START domain References External links Sterol carrier proteins in SCOP SCP-2 sterol transfer family in Pfam Peripheral membrane proteins Protein domains Protein families Water-soluble transporters
https://en.wikipedia.org/wiki/Indicators%20of%20spatial%20association
Indicators of spatial association are statistics that evaluate the existence of clusters in the spatial arrangement of a given variable. For instance, if we are studying cancer rates among census tracts in a given city local clusters in the rates mean that there are areas that have higher or lower rates than is to be expected by chance alone; that is, the values occurring are above or below those of a random distribution in space. Global indicators Notable global indicators of spatial association include: Global Moran's I: The most commonly used measure of global spatial autocorrelation or the overall clustering of the spatial data developed by Patrick Alfred Pierce Moran. Geary's C (Geary's Contiguity Ratio): A measure of global spatial autocorrelation developed by Geary in 1954. It is inversely related to Moran's I, but more sensitive to local autocorrelation than Moran's I. Getis–Ord G (Getis–Ord global G, Geleral G-Statistic): Introduced by Getis and Ord in 1992 to supplement Moran's I. Local indicators Notable local indicators of spatial association (LISA) include: Local Moran's I: Derived from Global Moran's I, it was introduced by Luc Anselin in 1995 and can be computed using GeoDa. Getis–Ord Gi (local Gi): Developed by Getis and Ord based on their global G. INDICATE's IN: Originally developed to assess the spatial behaviour of stars, can be computed for any discrete 2+D dataset using python-based INDICATE tool available from GitHub. See also Spatial analys
https://en.wikipedia.org/wiki/Amphirhina
Amphirhina are animals, a phylogenetic classification within the subphylum vertebrata. They are more commonly known as the Branch Gnathostomata, and are described as having double nasal chambers, or nostrils, and jaws. The parallel branch in this naming system is Monorhina (more commonly Agnatha), which possess a single nostril and a circular mouth without jaws. The ears of all animals within Amphirhina possess three semicircular canals. References Vertebrate taxonomy
https://en.wikipedia.org/wiki/Nikolai%20N.%20Kolesnikov
Nikolai Nikolayevich Kolesnikov (; born 1959) is a Russian scientist who works in the fields of semiconductor and superconductor crystal growth, semiconductor and carbon nanotechnologies. Kolesnikov graduated from Phys.-Chem. Department of the Moscow Chemico-Technological Institute in 1982 From 1982 to 1993 he worked in the Institute of Solid State Physics and since 1993 has been head of the Laboratory of Physical-Chemical Basis of Crystallisation of the ISSP. References 1959 births Russian physical chemists Russian inventors Living people
https://en.wikipedia.org/wiki/J.%20Michael%20Steele
John Michael Steele is C.F. Koo Professor of Statistics at the Wharton School of the University of Pennsylvania, and he was previously affiliated with Stanford University, Columbia University and Princeton University. Steele was elected the 2009 president of the Institute of Mathematical Statistics. Awards Source: Fellow, Institute for Mathematical Statistics, 1984; Fellow, American Statistical Association, 1989; Frank Wilcoxon Prize, American Society for Quality Control and the American Statistical Association, 1990 Chauvenet Prize (with Vladimir Pozdnyakov), in 2020, for their paper "Buses, Bullies, and Bijections" Books References External links J. Michael Steele's homepage 20th-century American mathematicians 21st-century American mathematicians Living people Probability theorists Year of birth missing (living people) Fellows of the American Statistical Association Presidents of the Institute of Mathematical Statistics Wharton School of the University of Pennsylvania faculty Stanford University Department of Statistics faculty Columbia University faculty Princeton University faculty