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https://en.wikipedia.org/wiki/N-acetyllactosamine%20synthase | N-acetyllactosamine synthase is a galactosyltransferase enzyme. It is a component of lactose synthase This enzyme modifies the connection between two molecule UDP-galactose and N-actyl-D-glucosamine and generates two different molecules UDP and N-acetyllactosamine as products. The main function of the enzyme is associated with the biosynthesis of glycoproteins and glycolipids in both human and animals. In human, the activity of this enzyme can be found in Golgi apparatus.
It is classified under .
The lack of this enzyme leads to glycolysation which is a serious neurological disease. The nature of the disease causes fluid in the brain, abnormal inflammatory response and abnormal bleeding issues.
See also
N-Acetylglucosamine
References
External links
EC 2.4.1 |
https://en.wikipedia.org/wiki/Lactose%20synthase | Lactose synthase is an enzyme that generates lactose from glucose and UDP-galactose.
It is classified under .
It consists of N-acetyllactosamine synthase and alpha-lactalbumin. Alpha-lactalbumin, which is expressed in response to prolactin, increases the affinity of N-acetyllactosamine synthase for its substrate, causing increased production of lactose during lactation.
N-acetyllactosamine synthase falls under the category of beta-1,4-galactosyltransferase, a type-II membrane protein found in the Golgi. Alpha-lactalbumin is a Ca2+ binding protein specific to mammary glands. Beta-1,4-galactosyltransferase consists of the catalytic component and alpha-lactalbumin consists of the regulatory component of lactose synthase. Alpha-lactalbumin promotes glucose binding to beta-1,4-galactosyltransferase. The beta-1,4-galactosyltransferase catalytic component consists of two flexible loops: small loop and large loop. The small loop consists of a Trp residue (Trp314) with surrounding glycine residues, meanwhile the large loop makes up amino acid residues 345 to 365. The Trp residue in the small loop moves allowing for the sugar nucleotide to be locked into the binding site. This causes a conformational change in the large loop which then creates sites for oligosaccharide and metal ion binding, and protein-protein interactions for alpha-lactalbumin.
References
External links
EC 2.4.1 |
https://en.wikipedia.org/wiki/Epalrestat | Epalrestat is a carboxylic acid derivative and a noncompetitive and reversible aldose reductase inhibitor used for the treatment of diabetic neuropathy, which is one of the most common long-term complications in patients with diabetes mellitus. It reduces the accumulation of intracellular sorbitol which is believed to be the cause of diabetic neuropathy, retinopathy and nephropathy It is well tolerated, with the most commonly reported adverse effects being gastrointestinal issues such as nausea and vomiting, as well as increases in certain liver enzymes.
Chemically, epalrestat is unusual in that it is a drug that contains a rhodanine group.
Aldose reductase is the key enzyme in the polyol pathway whose enhanced activity is the basis of diabetic neuropathy. Aldose reductase inhibitors (ARI) target this enzyme. Out of the many ARIs developed, ranirestat and fidarestat are in the trial stage. Others have been discarded due to unacceptable adverse effects or weak efficacy. Epalrestat is the only ARI commercially available. It is easily absorbed into the neural tissue and inhibits the enzyme with minimum side effects.
Evidence
It has been demonstrated in animal experiments that there is an improvement in sorbitol levels and Na+/K+ ATPase activity leading to improved nerve conduction velocity. Diabetic rats treated with epalrestat showed improvement in morphological abnormalities of nerves.
In a placebo controlled double blind trial of 196 patients, it was shown that Epalrestat |
https://en.wikipedia.org/wiki/Nuclear%20envelope | The nuclear envelope, also known as the nuclear membrane, is made up of two lipid bilayer membranes that in eukaryotic cells surround the nucleus, which encloses the genetic material.
The nuclear envelope consists of two lipid bilayer membranes: an inner nuclear membrane and an outer nuclear membrane. The space between the membranes is called the perinuclear space. It is usually about 10–50 nm wide. The outer nuclear membrane is continuous with the endoplasmic reticulum membrane. The nuclear envelope has many nuclear pores that allow materials to move between the cytosol and the nucleus. Intermediate filament proteins called lamins form a structure called the nuclear lamina on the inner aspect of the inner nuclear membrane and give structural support to the nucleus.
Structure
The nuclear envelope is made up of two lipid bilayer membranes, an inner nuclear membrane and an outer nuclear membrane. These membranes are connected to each other by nuclear pores. Two sets of intermediate filaments provide support for the nuclear envelope. An internal network forms the nuclear lamina on the inner nuclear membrane. A looser network forms outside to give external support. The actual shape of the nuclear envelope is irregular. It has invaginations and protrusions and can be observed with an electron microscope.
Outer membrane
The outer nuclear membrane also shares a common border with the endoplasmic reticulum. While it is physically linked, the outer nuclear membrane contains prote |
https://en.wikipedia.org/wiki/Lanthanum%20strontium%20manganite | Lanthanum strontium manganite (LSM or LSMO) is an oxide ceramic material with the general formula La1−xSrxMnO3, where x describes the doping level.
It has a perovskite-based crystal structure, which has the general form ABO3. In the crystal, the 'A' sites are occupied by lanthanum and strontium atoms, and the 'B' sites are occupied by the smaller manganese atoms. In other words, the material consists of lanthanum manganite with some of the lanthanum atoms substitutionally doped with strontium atoms. The strontium (valence 2+) doping on lanthanum (valence 3+) introduces extra holes in the valence band and thus increases electronic conductivity.
Depending on the x value in La1−xSrxMnO3, the unit cell of LSMO can be rhombohedral, cubic, or hexagonal. This change in the unit cell is explained on the basis of the Goldschmidt tolerance factor for perovskites. The change in the oxidation state of the Mn cation in LSMO can be readily observed through the position of the XPS peak for the Mn 2p3/2 orbital, and the interesting ferromagnetic ordering obtained when x=0.5 and 0.7 in the La1−xSrxMnO3.
LSM has a rich electronic phase diagram, including a doping-dependent metal-insulator transition, paramagnetism and ferromagnetism. The existence of a Griffith phase has been reported as well.
LSM is black in color and has a density of approximately 6.5 g/cm3. The actual density will vary depending on the processing method and actual stoichiometry. LSM is primarily an electronic conduct |
https://en.wikipedia.org/wiki/PDE3%20inhibitor | A PDE3 inhibitor is a drug which inhibits the action of the phosphodiesterase enzyme PDE3. They are used for the therapy of acute heart failure and cardiogenic shock.
Medical uses
Cardiac
Amrinone, milrinone and enoximone are used clinically for short-term treatment of cardiac failure in the presence of cardiogenic shock.
PDE3 inhibitors are indicated as inotropics for the therapy of acute heart failure if catecholamines are ineffective. Well controlled studies have shown that these drugs generally increase mortality, when used for the therapy of acute heart failure, so they have to be applied under close observation.
Peripheral artery disease
Cilostazol is used for the treatment of intermittent claudication.
This drug has a much weaker positive inotropic effect than those drugs used for the therapy of acute heart failure,
and lacks significant adverse cardiac effects.
Contraindications
Cardiac
Contraindications are severe obstructive cardiomyopathy, hypovolemia, tachycardia, and ventricular aneurysm. Breast feeding is prohibited during treatment.
Adverse effects
Cardiac
The most important adverse effects when used for the therapy of acute heart failure are arrhythmia, thrombocytopenia and increased transaminase levels.
Types
Approved PDE3 inhibitors include the following:
amrinone
cilostazol
milrinone
enoximone
pimobendan (approved for human use in Japan, approved for dogs elsewhere)
Mechanism of action
PDE3 inhibitors are a type of phosphodiesterase inhibitors. |
https://en.wikipedia.org/wiki/Genetic%20pollution | Genetic pollution is a term for uncontrolled gene flow into wild populations. It is defined as "the dispersal of contaminated altered genes from genetically engineered organisms to natural organisms, esp. by cross-pollination", but has come to be used in some broader ways. It is related to the population genetics concept of gene flow, and genetic rescue, which is genetic material intentionally introduced to increase the fitness of a population. It is called genetic pollution when it negatively impacts the fitness of a population, such as through outbreeding depression and the introduction of unwanted phenotypes which can lead to extinction.
Conservation biologists and conservationists have used the term to describe gene flow from domestic, feral, and non-native species into wild indigenous species, which they consider undesirable. They promote awareness of the effects of introduced invasive species that may "hybridize with native species, causing genetic pollution". In the fields of agriculture, agroforestry and animal husbandry, genetic pollution is used to describe gene flows between genetically engineered species and wild relatives. The use of the word "pollution" is meant to convey the idea that mixing genetic information is bad for the environment, but because the mixing of genetic information can lead to a variety of outcomes, "pollution" may not always be the most accurate descriptor.
Gene flow to wild population
Some conservation biologists and conservationists h |
https://en.wikipedia.org/wiki/Tryptophan%20tryptophylquinone | Tryptophan tryptophylquinone (TTQ) is an enzyme cofactor, generated by posttranslational modification of amino acids within the protein. Methylamine dehydrogenase (MADH), an amine dehydrogenase, requires TTQ for its catalytic function.
See also
Amicyanin
References
Alpha-Amino acids
Amino acid derivatives
Tryptamines
Indolequinones |
https://en.wikipedia.org/wiki/Genetic%20erosion | Genetic erosion (also known as genetic depletion) is a process where the limited gene pool of an endangered species diminishes even more when reproductive individuals die off before reproducing with others in their endangered low population. The term is sometimes used in a narrow sense, such as when describing the loss of particular alleles or genes, as well as being used more broadly, as when referring to the loss of a phenotype or whole species.
Genetic erosion occurs because each individual organism has many unique genes which get lost when it dies without getting a chance to breed. Low genetic diversity in a population of wild animals and plants leads to a further diminishing gene pool – inbreeding and a weakening immune system can then "fast-track" that species towards eventual extinction.
By definition, endangered species suffer varying degrees of genetic erosion. Many species benefit from a human-assisted breeding program to keep their population viable, thereby avoiding extinction over long time-frames. Small populations are more susceptible to genetic erosion than larger populations.
Genetic erosion gets compounded and accelerated by habitat loss and habitat fragmentation – many endangered species are threatened by habitat loss and (fragmentation) habitat. Fragmented habitat create barriers in gene flow between populations.
The gene pool of a species or a population is the complete set of unique alleles that would be found by inspecting the genetic material of ev |
https://en.wikipedia.org/wiki/Borel%20fixed-point%20theorem | In mathematics, the Borel fixed-point theorem is a fixed-point theorem in algebraic geometry generalizing the Lie–Kolchin theorem. The result was proved by .
Statement
If G is a connected, solvable, linear algebraic group acting regularly on a non-empty, complete algebraic variety V over an algebraically closed field k, then there is a G fixed-point of V.
A more general version of the theorem holds over a field k that is not necessarily algebraically closed. A solvable algebraic group G is split over k or k-split if G admits a composition series whose composition factors are isomorphic (over k) to the additive group or the multiplicative group . If G is a connected, k-split solvable algebraic group acting regularly on a complete variety V having a k-rational point, then there is a G fixed-point of V.
References
External links
Fixed-point theorems
Group actions (mathematics)
Theorems in algebraic geometry |
https://en.wikipedia.org/wiki/Exoglycosidase | An exoglycosidase is a glycoside hydrolase enzyme which breaks the glycosidic bonds at the residue.
Exoglyxosidase breaks the molecule in the interior
See also
Endoglycosidase
External links
Enzymes |
https://en.wikipedia.org/wiki/L1210%20cells | L1210 is a mouse lymphocytic leukemia cell line which is derived from the ascitic fluid of 8-month-old female DBA/2 strain mice. While they are lymphocytic B-cells they are more like lymphoblasts in morphology, develop massive tumours in nude mice after a latent period of 7-10 days.
References
External links
Cellosaurus entry for L1210
Rodent cell lines
Lymphocytes |
https://en.wikipedia.org/wiki/SPI%20200%20futures%20contract | The SPI 200 Futures contract is the benchmark equity index futures contract in Australia, based on the S&P/ASX 200 Index. It provides all the traditional benefits of equity index derivatives. The SPI 200 is ranked in the top 10 equity index contracts in Asia in terms of traded volume.
Quarterly and serial futures and options are available. March, June, September, December up to six quarter months ahead and serial months up to two non-financial quarter months ahead.
See also
Stock market index future
Derivatives (finance)
Futures markets
Finance in Australia |
https://en.wikipedia.org/wiki/1965%E2%80%9366%20Serie%20A | The 1965–66 Serie A season was won by Internazionale.
Teams
Brescia, Napoli and SPAL had been promoted from Serie B.
Final classification
Results
Top goalscorers
References
Almanacco Illustrato del Calcio - La Storia 1898-2004, Panini Edizioni, Modena, September 2005
External links
- All results on RSSSF Website.
Serie A seasons
Italy
1965–66 in Italian football leagues |
https://en.wikipedia.org/wiki/Systematic%20investment%20plan | A systematic investment plan (SIP) is an investment vehicle offered by many mutual funds to investors, allowing them to invest small amounts periodically instead of lump sums. The frequency of investment is monthly, quarterly, semi-annually and annually.
Overview
In SIPs, a fixed amount of money is debited by the investors in bank accounts periodically and invested in a specified mutual fund. The investor is allocated several units according to the current Net asset value. Every time a sum is invested, more units are added to the investor's account.
The strategy claims to free the investors from speculating in volatile markets by dollar cost averaging as the investor is getting more units when the price is low and fewer units when the price is high. In the long run, the average cost per unit is supposed to be lower.
SIP claims to encourage disciplined investment. SIPs are flexible; the investors may stop investing in a plan anytime or may choose to increase or decrease the investment amount. SIP is usually recommended to retail investors who do not have the resources to pursue active investment.
Benefits of SIP
The benefits of Systematic Investment Plans (SIPs) include:
Cost averaging: SIPs allow investors to invest a fixed amount regularly, regardless of market conditions. This strategy helps buy more units when prices are low and fewer when prices are high, potentially reducing the average cost per unit over the long run.
Disciplined investing: SIPs encourage disci |
https://en.wikipedia.org/wiki/Tijs | Tijs is a Dutch male given name. It can be a derivative form of Matthijs, which is the Dutch form of Matthew or Matthias, or a short form of Timothijs or Timotheus, Dutch forms of Timothy. Another spelling of this name is Thijs.
It may refer to:
Tijs Goldschmidt (born 1953), Dutch writer and evolutionary biologist
Tijs Tinbergen (born c. 1947), Dutch filmmaker
Tiësto (born Tijs Michiel Verwest, 1969), Dutch DJ
Dutch masculine given names
Masculine given names |
https://en.wikipedia.org/wiki/Alloneuron%20dorrii | Alloneuron dorrii is a species of plant in the family Melastomataceae. It is endemic to Ecuador. Its natural habitat is subtropical or tropical moist montane forests.
References
dorrii
Endemic flora of Ecuador
Vulnerable plants
Taxonomy articles created by Polbot |
https://en.wikipedia.org/wiki/Alloneuron | Alloneuron is a genus of plant in family Melastomataceae. It contains the following species (shrubs or trees):
Alloneuron glomeratum C.Ulloa & Michelang.
Alloneuron liron B.Walln.
Alloneuron majus (Markgr.) Markgr. ex J.F.Macbr.
Alloneuron ronliesneri B.Walln.
Alloneuron ulei Pilg.
Synonyms:
The new genus Wurdastom is described to include 8 species described by Wurdack,
Alloneuron bullatum Wurdack = Wurdastom bullata (Wurdack) B.Walln.
Alloneuron cuatrecasasii Wurdack = Wurdastom cuatrecasasii (Wurdack) B.Walln.
Alloneuron dorrii, Wurdack = Wurdastom dorrii (Wurdack) B.Walln.
Alloneuron dudleyi Wurdack = Wurdastom dudleyi (Wurdack) B.Walln.
Alloneuron ecuadorense, Wurdack = Wurdastom ecuadorensis (Wurdack) B.Walln.
Alloneuron hexamerum Wurdack = Wurdastom hexamera (Wurdack) B.Walln.
Alloneuron sneidernii Wurdack = Wurdastom sneidernii (Wurdack) B.Walln.
Alloneuron subglabrum Wurdack = Wurdastom subglabra (Wurdack) B.Walln.
References
Melastomataceae genera
Taxonomy articles created by Polbot
Taxa named by Robert Knud Friedrich Pilger |
https://en.wikipedia.org/wiki/Alloneuron%20ecuadorense | Alloneuron ecuadorense is a species of plant in the family Melastomataceae. It is endemic to Ecuador. Its natural habitat is subtropical or tropical moist montane forests.
References
ecuadorense
Endemic flora of Ecuador
Vulnerable plants
Taxonomy articles created by Polbot
Plants described in 1981 |
https://en.wikipedia.org/wiki/Manning%20criteria | The Manning criteria are a diagnostic algorithm used in the diagnosis of irritable bowel syndrome (IBS). The criteria consist of a list of questions the physician can ask the patient. The answers are used in a process to produce a diagnostic decision regarding whether the patient can be considered to have IBS.
The Manning criteria have been compared with other diagnostic algorithms for IBS, such as the Rome I criteria, the Rome II process, and the Kruis criteria. A 2013 validation study found the Manning criteria to have less sensitivity but more specificity than the Rome criteria.
The threshold for a positive diagnosis varies from two to four of the Manning criteria below.
Onset of pain linked to more frequent bowel movements
Looser stools associated with onset of pain
Pain relieved by passage of stool
Noticeable abdominal bloating
Sensation of incomplete evacuation more than 25% of the time
Diarrhea with mucus more than 25% of the time
References
Gastroenterology
Ailments of unknown cause
Syndromes
Conditions diagnosed by stool test
Abdominal pain
Diagnostic gastroenterology |
https://en.wikipedia.org/wiki/Electron-transferring-flavoprotein%20dehydrogenase | Electron-transferring-flavoprotein dehydrogenase (ETF dehydrogenase or electron transfer flavoprotein-ubiquinone oxidoreductase, ) is an enzyme that transfers electrons from electron-transferring flavoprotein in the mitochondrial matrix, to the ubiquinone pool in the inner mitochondrial membrane. It is part of the electron transport chain. The enzyme is found in both prokaryotes and eukaryotes and contains a flavin and FE-S cluster. In humans, it is encoded by the ETFDH gene. Deficiency in ETF dehydrogenase causes the human genetic disease multiple acyl-CoA dehydrogenase deficiency.
Function
ETQ-QO links the oxidation of fatty acids and some amino acids to oxidative phosphorylation in the mitochondria. Specifically, it catalyzes the transfer of electrons from electron transferring flavoprotein (ETF) to ubiquinone, reducing it to ubiquinol. The entire sequence of transfer reactions is as follows:
Acyl-CoA → Acyl-CoA dehydrogenase → ETF → ETF-QO → UQ → Complex III.
Catalyzed reaction
The overall reaction catalyzed by ETF-QO is as follows:
ETF-QO(red) + ubiquinone ↔ ETF-QO(ox) + ubiquinol
Enzymatic activity is usually assayed spectrophotometrically by reaction with octanoyl-CoA as the electron donor and ubiquinone-1 as the electron acceptor. The enzyme can also be assayed via disproportionation of ETF semiquinone. Both reactions are below:
Octanoyl-CoA + Q1 ↔ Q1H2 + Oct-2-enoyl-CoA
2 ETF1- ↔ ETFox + ETF2-
Structure
ETF-QO consists of one structural domain with t |
https://en.wikipedia.org/wiki/Electron-transferring%20flavoprotein | An electron transfer flavoprotein (ETF) or electron transfer flavoprotein complex (CETF) is a flavoprotein located on the matrix face of the inner mitochondrial membrane and functions as a specific electron acceptor for primary dehydrogenases, transferring the electrons to terminal respiratory systems such as electron-transferring-flavoprotein dehydrogenase. They can be functionally classified into constitutive, "housekeeping" ETFs, mainly involved in the oxidation of fatty acids (Group I), and ETFs produced by some prokaryotes under specific growth conditions, receiving electrons only from the oxidation of specific substrates (Group II).
ETFs are heterodimeric proteins composed of an alpha and beta subunit (ETFA and ETFB), and contain an FAD cofactor and AMP. ETF consists of three domains: domains I and II are formed by the N- and C-terminal portions of the alpha subunit, respectively, while domain III is formed by the beta subunit. Domains I and III share an almost identical alpha-beta-alpha sandwich fold, while domain II forms an alpha-beta-alpha sandwich similar to that of bacterial flavodoxins. FAD is bound in a cleft between domains II and III, while domain III binds the AMP molecule. Interactions between domains I and III stabilise the protein, forming a shallow bowl where domain II resides.
Mutation in ETFs can lead to deficiency of passing reducing equivalent of FADH2 to electron transport chain, causing Glutaric acidemia type 2
See also
Electron transport chain
E |
https://en.wikipedia.org/wiki/Anthurium%20polyneuron | Anthurium polyneuron is a species of plant in the family Araceae. It is endemic to Ecuador. Its natural habitat is subtropical or tropical moist montane forests. It is threatened by habitat loss.
References
Endemic flora of Ecuador
polyneuron
Data deficient plants
Taxonomy articles created by Polbot |
https://en.wikipedia.org/wiki/Arachniodes | Arachniodes is a fern genus in the family Dryopteridaceae (wood ferns), subfamily Dryopteridoideae, in the Pteridophyte Phylogeny Group classification of 2016 (PPG I). A number of species in this genus are known as "holly ferns".
The genus Arachniodes was first published by Carl Ludwig von Blume in 1828, with the single Indonesian species Arachniodes aspidioides. The genus was not widely recognized until Mary Douglas Tindale transferred the two species (Byrsopteris amabilis and Byrsopteris aristata) into it in 1961.
Species
The Pteridophyte Phylogeny Group classification of 2016 (PPG I) considers Arachniodes to have 60 species. , the Checklist of Ferns and Lycophytes of the World accepted 78 species:
Arachniodes ailaoshanensis Ching
Arachniodes amabilis (Blume) Tindale
Arachniodes amoena (Ching) Ching
Arachniodes aristata (G.Forst.) Tindale
Arachniodes assamica (Kuhn) Ohwi
Arachniodes bella (C.Chr.) Ching
Arachniodes blinii (H.Lév.) Nakaike
Arachniodes carvifolia (Kunze) Ching
Arachniodes caudata Ching
Arachniodes cavaleriei (Christ) Ohwi
Arachniodes chinensis (Rosenst.) Ching
Arachniodes coniifolia (T.Moore) Ching
Arachniodes cornucervi (D.Don) Fraser-Jenk.
Arachniodes daklakensis Li Bing Zhang, N.T.Lu & X.M.Zhou
Arachniodes davalliaeformis (Christ) Nakaike
Arachniodes denticulata (Sw.) Ching
Arachniodes fengii Ching
Arachniodes festina (Hance) Ching
Arachniodes formosa (Fée) Ching
Arachniodes formosissima (Goldm.) Nakaike
Arachniodes gigantea Ching
Arachniodes globisora |
https://en.wikipedia.org/wiki/Archidium | Archidium is a genus of mosses; it is the only genus in the family Archidiaceae and order Archidiales.
Classification
The genus Archidium includes 35 species (this list may be incomplete):
Archidium acanthophyllum
Archidium alternifolium
Archidium andersonianum
Archidium donnellii
Archidium elatum, Dixon & Sainsbury
Archidium hallii
Archidium minus
Archidium minutissimum
Archidium muellerianum
Archidium ohioense
Archidium stellatum
Archidium tenerrimum
Archidium wattsii
References
External links
Moss genera
Dicranidae
Taxonomy articles created by Polbot |
https://en.wikipedia.org/wiki/Spar%20box | Spar boxes are a type of folk art, crafted by miners to display minerals and crystals they have found.
External links
The Story of Spar Boxes
NATIONAL SPAR BOX COLLECTION TO SHOW OFF MINING HERITAGE AT KILLHOPE
The Spar Box
Folk art |
https://en.wikipedia.org/wiki/Arachidonate%205-lipoxygenase%20inhibitor | Arachidonate 5-lipoxygenase inhibitors are compounds that slow or stop the action of the arachidonate 5-lipoxygenase (5-lipoxygenase or 5-LOX) enzyme, which is responsible for the production of inflammatory leukotrienes. The overproduction of leukotrienes is a major cause of inflammation in asthma, allergic rhinitis, and osteoarthritis.
Examples of 5-LOX inhibitors include the pharmaceutical drugs meclofenamate sodium, zileuton and the natural products myxochelins/pseudochelin as well as nordihydroguaiaretic acid (NDGA).
Some chemicals found in trace amounts in food, as well as some dietary supplements, have been shown to inhibit 5-LOX; these include baicalein, caffeic acid, curcumin, hyperforin and St John's wort.
Acetyl-keto-beta-boswellic acid (AKBA), one of the bioactive boswellic acids found in Boswellia serrata (Indian Frankincense) has been found to inhibit 5-lipoxygenase strongly as an allosteric inhibitor. Boswellia administration has been shown to reduce brain edema in patients irradiated for brain tumor and it's believed to be due to 5-lipoxygenase inhibition.
See also
Antileukotriene agents
Arachidonate 5-lipoxygenase ALOX5-inhibiting drugs
References
External links
Human Metabolome Database – Metabolites of 5-LOX
Oxidoreductase inhibitors |
https://en.wikipedia.org/wiki/Tilera | Tilera Corporation was a fabless semiconductor company focusing on manycore embedded processor design. The company shipped multiple processors in the TILE64, TILEPro64, and TILE-Gx lines.
After a series of company acquisitions, Tilera's intellectual property was eventually acquired by Nvidia (via EZChip, then Mellanox), which now ships BlueField products that descend from the Tilera designs.
History
In 1990, Anant Agarwal led a team of researchers at Massachusetts Institute of Technology to develop scalable multi-processor system built out of large numbers of single chip processors. Alewife machines integrated both shared memory and user-level message passing for inter-node communications.
In 1997, Agarwal proposed a follow-on project using a mesh technology to connect multiple cores. The follow-on project, named RAW, commenced in 1997, and was supported by DARPA/NSF's funding of tens of millions, resulting in the first 16-processor tiles multicore and proving the mesh and compiler technology.
Tilera was founded in October 2004, by Agarwal, Devesh Garg, and Vijay K. Aggarwal. Tilera launched its first product, the 64-core TILE64 processor, in August 2007. Tilera raised more than $100 million in venture funding from Bessemer Venture Partners, Walden International, Columbia Capital and VentureTech Alliance, with strategic investments from Broadcom, Quanta Computer and NTT. The company was headquartered in San Jose, California and operated a research and development facilit |
https://en.wikipedia.org/wiki/Bolbitis | Bolbitis is a genus of ferns in the family Dryopteridaceae, subfamily Elaphoglossoideae, in the Pteridophyte Phylogeny Group classification of 2016 (PPG I).
Two particular members of the genus are often grown as immersed water plants in aquaria, B. heudelotii, and B. heteroclita. B. heudelotii, the African water fern, normally grows submerged in its native habitat, while B. heteroclita normally grows on the margin of water bodies, but will also grow submerged.
Species
, the Checklist of Ferns and Lycophytes of the World accepted the following species:
Bolbitis acrostichoides (Afzel. ex Sw.) Ching
Bolbitis aliena (Sw.) Alston
Bolbitis andreisii Fraser-Jenk. & Kandel
Bolbitis angustipinna (Hayata) Itô
Bolbitis appendiculata (Willd.) K.Iwats.
Bolbitis aspleniifolia (Bory) K.Iwats.
Bolbitis auriculata (Lam.) Alston
Bolbitis beddomei Fraser-Jenk. & Gandhi
Bolbitis bipinnatifida (Mett. ex Kuhn) Ching
Bolbitis cadieri (Christ) Ching
Bolbitis changjiangensis F.G.Wang & F.W.Xing
Bolbitis christensenii (Ching) Ching
Bolbitis confertifolia Ching
Bolbitis costata (Wall. ex Hook.) Ching
Bolbitis crispatula (Wall. ex Hook.) Ching
Bolbitis cuneata (Bonap.) Fraser-Jenk.
Bolbitis curupirae (Lindm.) Ching
Bolbitis deltigera ([Wall. ex] Hook.) C.Chr.
Bolbitis feeiana (Copel.) Fraser-Jenk. & Gandhi
Bolbitis fengiana (Ching) S.Y.Dong
Bolbitis fluviatilis (Hook.) Ching
Bolbitis gaboonensis (Hook.) Alston
Bolbitis gemmifera (Hieron.) C.Chr.
Bolbitis hainanensis Ching & C.H.Wang
Bolbitis hastata |
https://en.wikipedia.org/wiki/HLA-DR53 | HLA-DR53 is an HLA-DR serotype that recognizes gene products of HLA-DRB4 locus. There are 13 alleles at this locus that encode 7 proteins.
DRB3, DRB4, and DRB5 are minor DR beta encoding loci, they have been recognized as having distinct evolution. and the DRB4 locus presence is linked to HLA-DR7 seropositivity. The DRB4*locus was apparently duplicated from an ancestor of the DRB1-DRB4 common locus around 5 million years ago.
DRB4 locus is only apparent in a small subset of DQ haplotypes, and most individuals lack DRB4. In addition the level of normal expression is 8 fold lower than the DRB1 in cells which can express both. and lowered because of both transcriptional and post-transcriptional regulation.
Alleles
DR53 reactive alleles: DRB4*0101, *0103
Unknown reactivity: *0102, *0104 to *0107
Null alleles: *0101102N, *01030102N, *0201N, *0301N
Associated diseases
DRB4*01 is positively associated with Erythema multiforme, Crohn's disease, myasthenia gravis, rheumatoid arthritis Hashimoto's thyroiditis, vitiligo, primary biliary cirrhosis, clozapine-induced agranulocytosis, Vogt–Koyanagi–Harada disease,
HLA-DRB1 linkage
HLA-DR53 serotypes (HLA-DRB4) is linked to the following HLADR serotypes (HLA-DRB1) allele groups:
HLA-DR4 - DRB1*04
HLA-DR7 - DRB1*07
HLA-DR9 - DRB1*09
References
HLA-DR haplotypes |
https://en.wikipedia.org/wiki/Heteroskedasticity-consistent%20standard%20errors | The topic of heteroskedasticity-consistent (HC) standard errors arises in statistics and econometrics in the context of linear regression and time series analysis. These are also known as heteroskedasticity-robust standard errors (or simply robust standard errors), Eicker–Huber–White standard errors (also Huber–White standard errors or White standard errors), to recognize the contributions of Friedhelm Eicker, Peter J. Huber, and Halbert White.
In regression and time-series modelling, basic forms of models make use of the assumption that the errors or disturbances ui have the same variance across all observation points. When this is not the case, the errors are said to be heteroskedastic, or to have heteroskedasticity, and this behaviour will be reflected in the residuals estimated from a fitted model. Heteroskedasticity-consistent standard errors are used to allow the fitting of a model that does contain heteroskedastic residuals. The first such approach was proposed by Huber (1967), and further improved procedures have been produced since for cross-sectional data, time-series data and GARCH estimation.
Heteroskedasticity-consistent standard errors that differ from classical standard errors may indicate model misspecification. Substituting heteroskedasticity-consistent standard errors does not resolve this misspecification, which may lead to bias in the coefficients. In most situations, the problem should be found and fixed. Other types of standard error adjustments, su |
https://en.wikipedia.org/wiki/Adobe%20Ultra | Adobe Ultra is a discontinued vector keying application, helping produce blue-screen/green-screen effects for video (although the background can actually be any color). Ultra performs complex image analysis to produce high quality chroma-key effects in less than ideal lighting environments. Ultra also included virtual set technology, which allows the keying of a subject into an animated virtual 3D environment.
Since its discontinuation as a standalone product, the functionalities of Ultra have been incorporated into other Adobe products, namely Adobe Visual Communicator (since 2007), Adobe Premiere Elements (since 2008), and Adobe Premiere Pro (since 2010).
Ultra was previously known as Serious Magic Ultra Key, and was acquired when Adobe purchased Serious Magic Inc. in 2006. Unlike many of the other applications in the Adobe Creative Suite, Adobe Ultra only runs on the Windows operating system.
Incorporation into other products
Ultra as a standalone application was distributed with Adobe Creative Suite 3 (released March 2007) but noticeably absent from CS4 (released October 2008) and CS5 (released April 2010). After CS3, the keyer from Ultra was integrated into two other Adobe products – Visual Communicator 3, and Premiere Elements.<ref name="VideoRoad">Adobe Blogs: The Video Road: What About Ultra, </ref>Adobe Visual Communicator 3 (released in September 2007) had the full vector keyer control of Ultra built into it, along with some simplified virtual sets. The vector |
https://en.wikipedia.org/wiki/Calceolaria%20obtusa | Calceolaria obtusa is an endangered species of plant in the Calceolariaceae family, the main obstacle for gene flow of this genre is ecogeographic isolation. originated from the southern Andes mountains located in Chile. This flowering plant is also one of the largest oil-producing plants.
References
Endemic flora of Ecuador
obtusa
Endangered plants
Taxonomy articles created by Polbot
Cosacov, Andrea, et al. “New Insights into the Phylogenetic Relationships, Character Evolution, and Phytogeographic Patterns Ofcalceolaria(Calceolariaceae).” American Journal of Botany, vol. 96, no. 12, 2009, pp. 2240–2255., https://doi.org/10.3732/ajb.0900165. |
https://en.wikipedia.org/wiki/Calymmodon | Calymmodon is a genus of ferns in the family Polypodiaceae, subfamily Grammitidoideae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I). Its known range is Sri Lanka, Thailand, Vietnam, Taiwan, Malesia, Australia, Micronesia and Polynesia.
Species
, the Checklist of Ferns and Lycophytes of the World accepted the following species and hybrids:
Calymmodon acrosoroides Parris
Calymmodon acutangularis Parris
Calymmodon asiaticus Copel.
Calymmodon atrichus Copel.
Calymmodon binaiyensis Parris
Calymmodon borneensis Parris
Calymmodon clavifer (Hook.) T.Moore
Calymmodon concinnus Parris
Calymmodon conduplicatus (Brause) Copel.
Calymmodon congestus Copel.
Calymmodon coriaceus Parris
Calymmodon cucullatus (Nees & Blume) C.Presl
Calymmodon curtus Parris
Calymmodon debilis Parris
Calymmodon decipiens Parris
Calymmodon fragilis Copel.
Calymmodon gibbsiae Parris
Calymmodon glabrescens Copel.
Calymmodon gracilis (Fée) Copel.
Calymmodon holttumii Parris
Calymmodon hyalinus Copel.
Calymmodon hygroscopicus Copel.
Calymmodon ichthyorhachioides Alston
Calymmodon innominatus Parris
Calymmodon kaniensis (Brause) Copel.
Calymmodon kanikehensis Parris
Calymmodon kinabaluensis Parris
Calymmodon latealatus Copel.
Calymmodon ledermannii Parris
Calymmodon linearis Parris
Calymmodon longipilosus Parris
Calymmodon luerssenianus (Domin) Copel.
Calymmodon mnioides Copel.
Calymmodon morobensis Parris
Calymmodon murkelensis Parris
Calymmodon muscoides (Copel.) Copel.
Calymmodon o |
https://en.wikipedia.org/wiki/Campyloneurum | Campyloneurum is a genus of ferns in the family Polypodiaceae, subfamily Polypodioideae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I). They are commonly known as strap ferns.
Species
, Checklist of Ferns and Lycophytes of the World accepted the following species:
Campyloneurum abruptum (Lindm.) B.León
Campyloneurum acrocarpon Fée
Campyloneurum aglaolepis (Alston) de la Sota
Campyloneurum amazonense B.León
Campyloneurum amphostenon (Kunze ex Klotzsch) Fée
Campyloneurum anetioides (Christ) R.M.Tryon & A.F.Tryon
Campyloneurum angustifolium (Sw.) Fée
Campyloneurum angustipaleatum (Alston) M.Mey. ex Lellinger
Campyloneurum aphanophlebium (Kunze) T.Moore
Campyloneurum asplundii (C.Chr.) Ching
Campyloneurum atlanticum R.C.Moran & Labiak
Campyloneurum austrobrasilianum (Alston) de la Sota
Campyloneurum brevifolium (Lodd. ex Link) Link
Campyloneurum centrobrasilianum Lellinger
Campyloneurum chlorolepis Alston
Campyloneurum chrysopodum (Klotzsch) Fée
Campyloneurum coarctatum (Kunze) Fée
Campyloneurum cochense (Hieron.) Ching
Campyloneurum costatum (Kunze) C.Presl
Campyloneurum decurrens (Raddi) C.Presl
Campyloneurum densifolium (Hieron.) Lellinger
Campyloneurum ensifolium (Willd.) J.Sm.
Campyloneurum falcoideum (Kuhn ex Hieron.) M.Mey. ex Lellinger
Campyloneurum fuscosquamatum Lellinger
Campyloneurum gracile A.Rojas
Campyloneurum inflatum M.Mey. ex Lellinger
Campyloneurum lorentzii (Hieron.) Ching
Campyloneurum macrosorum Fée
Campyloneurum magnificum T |
https://en.wikipedia.org/wiki/Jerry%20Kazdan | Jerry Lawrence Kazdan (born 31 October 1937 in Detroit, Michigan) is an American mathematician noted for his work in differential geometry and the study of partial differential equations. His contributions include the Berger–Kazdan comparison theorem, which was a key step in the proof of the Blaschke conjecture and the classification of Wiedersehen manifolds. His best-known work, done in collaboration with Frank Warner, dealt with the problem of prescribing the scalar curvature of a Riemannian metric.
Biography
Kazdan received his bachelor's degree in 1959 from Rensselaer Polytechnic Institute and his master's degree in 1961 from NYU. He obtained his PhD in 1963 from the Courant Institute of Mathematical Sciences at New York University; his thesis was entitled A Boundary Value Problem Arising in the Theory of Univalent Functions and was supervised by Paul Garabedian. He then took a position as a Benjamin Peirce Instructor at Harvard University. Since 1966, he has been a Professor of Mathematics at the University of Pennsylvania.
Dennis DeTurck was a student of his.
Honours
In 1999 he received the Lester Randolph Ford Award for his expository article Solving equations, an elegant legacy. In 2012 he became a fellow of the American Mathematical Society.
Major publications
DeTurck, Dennis M.; Kazdan, Jerry L. Some regularity theorems in Riemannian geometry. Ann. Sci. École Norm. Sup. (4) 14 (1981), no. 3, 249–260.
Kazdan, Jerry L.; Warner, F.W. Curvature functions for comp |
https://en.wikipedia.org/wiki/Afrocanthium%20keniense | Afrocanthium keniense is a species of flowering plant in the family Rubiaceae. It is endemic to Kenya. It is threatened by habitat loss.
Taxonomy
In 2004, a molecular phylogenetic study of DNA sequences found the genus Canthium to be polyphyletic. The authors of this study transferred 20 species, including Canthium keniense, to a new genus, Afrocanthium.
References
External links
World Checklist of Rubiaceae
Vanguerieae
Endemic flora of Kenya
Vulnerable flora of Africa
Taxonomy articles created by Polbot
Plants described in 1932 |
https://en.wikipedia.org/wiki/Starting%20vortex | In fluid dynamics, the starting vortex is a vortex which forms in the air adjacent to the trailing edge of an airfoil as it is accelerated from rest. It leaves the airfoil (which now has an equal but opposite "bound vortex" around it), and remains (nearly) stationary in the flow. It eventually decays through the action of viscosity, but before doing so it contributes significantly to wake turbulence.
The initial (and quite brief) presence of a starting vortex as an airfoil begins to move was predicted by early aerodynamicists, and eventually photographed.
Whenever the speed or angle of attack of an airfoil changes there is a corresponding amount of vorticity deposited in the wake behind the airfoil, joining the two trailing vortices. This vorticity is a continuum of mini-starting-vortexes. The wake behind an aircraft is a continuous sheet of weak vorticity, between the two trailing vortices, and this accounts for the changes in strength of the trailing vortices as the airspeed of the aircraft and angle of attack on the wing change during flight. (The strength of a vortex cannot change within the fluid except by the dissipative action of viscosity. Vortices either form continuous loops of constant strength, or they terminate at the boundary of the fluid - usually a solid surface such as the ground.)
The starting vortex is significant to an understanding of the Kutta condition and its role in the circulation around any airfoil generating lift.
The starting vortex has ce |
https://en.wikipedia.org/wiki/Casearia | Casearia is a plant genus in the family Salicaceae. The genus was included in the Flacourtiaceae under the Cronquist system of angiosperm classification, and earlier in the Samydaceae.
They are sometimes employed as honey plants, notably C. decandra and C. sylvestris. The latter species is occasionally used as food by the caterpillars of the two-barred flasher (Astraptes fulgerator). Several species are becoming rare due to deforestation. Some appear close to extinction, and C. quinduensis of Colombia and C. tinifolia from Mauritius seem to be extinct since some time in the 20th century and about 1976, respectively.
Selected species
Names brought to synonymy
Casearia elegans Standley, a synonym for Casearia bartlettii
References
External links
Taxonomy articles created by Polbot
Salicaceae genera
Taxa named by Nikolaus Joseph von Jacquin |
https://en.wikipedia.org/wiki/Ceradenia | Ceradenia is a genus of ferns in the family Polypodiaceae, subfamily Grammitidoideae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I).
Species
, the Checklist of Ferns and Lycophytes of the World accepted the following species:
Ceradenia albidula (Baker) L.E.Bishop
Ceradenia alboglandulosa (Bonap.) Parris
Ceradenia argyrata (Bory ex Willd.) Parris
Ceradenia arthrothrix L.E.Bishop & A.R.Sm.
Ceradenia asthenophylla L.E.Bishop ex A.R.Sm.
Ceradenia aulaeifolia L.E.Bishop ex A.R.Sm.
Ceradenia auroseiomena L.E.Bishop
Ceradenia ayopayana M.Kessler & A.R.Sm.
Ceradenia bishopii (Stolze) A.R.Sm.
Ceradenia brunneoviridis (Baker ex Jenman) L.E.Bishop
Ceradenia capillaris (Desv.) L.E.Bishop
Ceradenia clavipila L.E.Bishop ex M.Kessler & A.R.Sm.
Ceradenia comorensis (Baker) Parris
Ceradenia comosa L.E.Bishop
Ceradenia congesta (Copel.) L.E.Bishop ex A.R.Sm.
Ceradenia curvata (Sw.) L.E.Bishop
Ceradenia deltodon (Baker) Parris
Ceradenia dendrodoxa L.E.Bishop
Ceradenia discolor (Hook.) L.E.Bishop
Ceradenia farinosa (Hook.) L.E.Bishop
Ceradenia fendleri (Copel.) L.E.Bishop
Ceradenia fragillima (Copel.) L.E.Bishop
Ceradenia fucoides (Christ) L.E.Bishop
Ceradenia gameriana (Vareschi) Mostacero
Ceradenia glabra M.Kessler & A.R.Sm.
Ceradenia glaziovii (Baker) Labiak
Ceradenia herrerae (Copel.) L.E.Bishop
Ceradenia intonsa L.E.Bishop ex León-Parra & Mostacero
Ceradenia intricata (C.V.Morton) L.E.Bishop ex A.R.Sm.
Ceradenia itatiaiensis Labiak & Condack
Ceradenia ivohib |
https://en.wikipedia.org/wiki/WIBN | WIBN is an FM radio station licensed to the city of Earl Park, Indiana. The station operates on the FM radio frequency of 98.1 MHz, FM channel 251. The studios are located at 130 E. McConnell Street in Oxford, Indiana. The tower is located one mile east of Dunnington, Indiana, a small community in rural western Benton County.
History
WIBN signed on the air in 1983 at 98.3 on the FM dial originally built and owned by Frank and Sandra Hertel of Evansville, IN. The station originally broadcast at 3,000 watts and served specifically the communities of Earl Park, Fowler and Kentland. The studio and tower were both located in Earl Park. Initially, the format was a mix of country and Adult contemporary music. The station had stints doing each of the aforementioned formats exclusively throughout the 1980s.
By the mid-1980s, the station was purchased by Lafayette, Indiana radio pioneer Sidney Thompson. His company, known as IBN Broadcasting, began looking into ways to make the station more powerful as well as more profitable. The 98.3 frequency was very cluttered in northwestern Indiana at the time with three other stations occupying the frequency within a 100-mile radius of WIBN. In 1988, the FCC granted a request to move WIBN to 98.1 and strengthen its power from 3,000 watts to 25,000 watts. This power increase would also provide the station with primary coverage to larger Illinois towns such as Watseka and Hoopeston and secondary coverage to Greater Lafayette. Once the m |
https://en.wikipedia.org/wiki/Virus%20mutation | Virus mutation is mutation of viruses and may refer to:
The feature of viruses to cause mutation in the human genome
The feature of viruses to perform viral genetic change in their own genome. |
https://en.wikipedia.org/wiki/Guanylate%20cyclase%20activator | A guanylate cyclase activator (or "GUCA") is one of group of proteins which upregulates guanylate cyclase. It is also known as guanylate cyclase-activating protein, with the abbreviation "GCAP". Mutations can be associated with vision defects.
There are five genes involved:
, ,
,
References
External links
Proteins |
https://en.wikipedia.org/wiki/Air%20barrier | Air barriers control air leakage into and out of the building envelope. Air barrier products may take several forms:
Mechanically-attached membranes, also known as housewraps, usually a polyethylene-fiber or spun-bonded polyolefin, such as Tyvek is a generally accepted moisture barrier and an air barrier (ASTM E2178).
Self-adhered membranes, which are typically also a water-resistant barrier and a vapor barrier
Fluid-applied membranes, such as heavy-bodied paints or coatings including polymeric based and asphaltic based materials
Closed-cell medium density spray-applied polyurethane foam, which typically provides insulation as well
Some open-cell spray-applied polyurethane foam that are of high density
Boardstock, which includes 12 mm plywood or OSB, 25 mm extruded polystyrene, etc.
Air barriers are divided into air barrier materials, air barrier accessories, air barrier components, air barrier assemblies and air barrier systems.
Air barrier materials – Building materials that are designed and constructed to provide the principal plane of airtightness through an environmental separator, which has an air permeance rate no greater than 0.02 L/(s•m²) at a pressure difference of 75 Pa when tested in accordance with ASTM E 2178. Air barrier materials meet the requirements of the CAN/ULC S741 Air Barrier Material Specification. The air barrier materials are typically the "big" pieces of material used in an air barrier assembly.
Air barrier accessories – Products designated t |
https://en.wikipedia.org/wiki/Grammitis | Grammitis (dwarf polypody) is a genus of ferns in the family Polypodiaceae, subfamily Grammitidoideae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I). It had formerly been placed in the family Grammitidaceae, but this family is no longer recognized by most authors because phylogenetic analyses of DNA sequences have shown that it is embedded in Polypodiaceae.
The delimitation of Grammitis was drastically narrowed in the first decade of the 21st century. It now contains about 25 species. In 2003, a study of the distribution of grammitid ferns placed 11 species in the New World, 7 in Africa, and 4 in the Pacific.
The genus Grammitis was established by Olof Swartz around 1801. (sources vary on the exact date). The name is derived from Greek, gramma, grammatos meaning "a line or thread" and refers to the arrangement of the sori in some species. The type species for Grammitis is Grammitis marginella.
The only known fossil of a grammitid fern has been named Grammitis succinea, but it is not clear that it belongs to Grammitis as more recently defined. It was found in Oligocene amber from the Dominican Republic.
Circumscription
In a treatment of Grammitidaceae in 1990, Barbara S. Parris defined Grammitis broadly, to include about 400 species. At that time, she stated that "The treatment of Grammitis here as a large and diverse genus reflects our current lack of knowledge concerning relationships within the family". Other authors at that time circumsc |
https://en.wikipedia.org/wiki/Appleton%E2%80%93Hartree%20equation | The Appleton–Hartree equation, sometimes also referred to as the Appleton–Lassen equation is a mathematical expression that describes the refractive index for electromagnetic wave propagation in a cold magnetized plasma. The Appleton–Hartree equation was developed independently by several different scientists, including Edward Victor Appleton, Douglas Hartree and German radio physicist H. K. Lassen. Lassen's work, completed two years prior to Appleton and five years prior to Hartree, included a more thorough treatment of collisional plasma; but, published only in German, it has not been widely read in the English speaking world of radio physics. Further, regarding the derivation by Appleton, it was noted in the historical study by Gilmore that Wilhelm Altar (while working with Appleton) first calculated the dispersion relation in 1926.
Equation
The dispersion relation can be written as an expression for the frequency (squared), but it is also common to write it as an expression for the index of refraction:
The full equation is typically given as follows:
or, alternatively, with damping term and rearranging terms:
Definition of terms:
: complex refractive index
: imaginary unit
: electron collision frequency
: angular frequency
: ordinary frequency (cycles per second, or Hertz)
: electron plasma frequency
: electron gyro frequency
: permittivity of free space
: ambient magnetic field strength
: electron charge
: electron mass
: angle between the ambient magn |
https://en.wikipedia.org/wiki/Pottiales | Pottiales is an order of mosses in the subclass Dicranidae.
Classification
The following families are recognised in Bryophyte Biology:
Pottiaceae
Pleurophascaceae
Serpotortellaceae
Mitteniaceae
Some other families are recognised by other sources:
Ephemeraceae – this putative family is characterized by highly simplified vegetative and sporogenous bodies and contains two genera, Ephemerum and Micromitrium. However, phylogenetic analysis finds it polyphyletic, with Ephemerum nested in Pottiaceae and Micromitrium recovered among the Dicranales, closely related to the Leucobryaceae, and assigned a new family, Micromitriaceae.
Hypodontiaceae – family containing the genus Hypodontium. Alternatively placed in Dicranales
Splachnobryaceae – containing the genera Splachnobryum and Koponobryum
Bryobartramiaceae – family containing a single genus with one species, Bryobartramia novae-valesiae
Cinclidotaceae (lattice mosses) – family containing the genus Cinclidotus. Alternately place in Pottiaceae.
References
Dicranidae
Moss orders |
https://en.wikipedia.org/wiki/CROT | CROT may refer to:
CROT (gene), which encodes the enzyme peroxisomal carnitine O-octanoyltransferase
C-ROT gate, a component in quantum logic computers |
https://en.wikipedia.org/wiki/PAS%20diastase%20stain | Periodic acid–Schiff–diastase (PAS-D, PAS diastase) stain is a periodic acid–Schiff (PAS) stain used in combination with diastase, an enzyme that breaks down glycogen. PAS-D is a stain often used by pathologists as an ancillary study in making a histologic diagnosis on paraffin-embedded tissue specimens. PAS stain typically gives a magenta color in the presence of glycogen. When PAS and diastase are used together, a light pink color replaces the deep magenta. Differences in the intensities of the two stains (PAS and PAS-D) can be attributed to different glycogen concentrations and can be used to semiquantify glycogen in samples. In practice, the tissue is deparaffinized, the diastase incubates, and then the PAS stain is applied.
An example of PAS-D in use is in showing gastric/duodenal metaplasia in duodenal adenomas. PAS diastase stain is also used to identify alpha-1 antitrypsin globules in hepatocytes, which is a characteristic finding of alpha-1 antitrypsin deficiency.
PAS diastase stain is also used in diagnosing Whipple’s disease, as the foamy macrophages that infiltrate the lamina propria of the small intestine in this disease possess PAS-positive, diastase-resistant inclusions.
Additional images
See also
Periodic acid-Schiff stain
Diastase
References
External links
PAS Diastase Protocol
Staining |
https://en.wikipedia.org/wiki/Discontinuous%20Galerkin%20method | In applied mathematics, discontinuous Galerkin methods (DG methods) form a class of numerical methods for solving differential equations. They combine features of the finite element and the finite volume framework and have been successfully applied to hyperbolic, elliptic, parabolic and mixed form problems arising from a wide range of applications. DG methods have in particular received considerable interest for problems with a dominant first-order part, e.g. in electrodynamics, fluid mechanics and plasma physics.
Discontinuous Galerkin methods were first proposed and analyzed in the early 1970s as a technique to numerically solve partial differential equations. In 1973 Reed and Hill introduced a DG method to solve the hyperbolic neutron transport equation.
The origin of the DG method for elliptic problems cannot be traced back to a single publication as features such as jump penalization in the modern sense were developed gradually. However, among the early influential contributors were Babuška, J.-L. Lions, Joachim Nitsche and Miloš Zlámal. DG methods for elliptic problems were already developed in a paper by Garth Baker in the setting of 4th order equations in 1977. A more complete account of the historical development and an introduction to DG methods for elliptic problems is given in a publication by Arnold, Brezzi, Cockburn and Marini. A number of research directions and challenges on DG methods are collected in the proceedings volume edited by Cockburn, Karniadakis a |
https://en.wikipedia.org/wiki/Graph%20cut | Graph cut may refer to:
Cut (graph theory), in mathematics
Graph cut optimization
Graph cuts in computer vision |
https://en.wikipedia.org/wiki/Tim%20Hrynewich | Tim Hrynewich (born October 2, 1963) is a Canadian former professional ice hockey left winger. He played 55 NHL games for the Pittsburgh Penguins between 1982 and 1984.
Career statistics
Regular season and playoffs
References
External links
1963 births
Living people
Baltimore Skipjacks players
Canadian ice hockey left wingers
Flint Spirits players
Fort Wayne Komets players
Ice hockey people from Ontario
Milwaukee Admirals (IHL) players
Muskegon Lumberjacks players
People from Leamington, Ontario
Sportspeople from Essex County, Ontario
Pittsburgh Penguins players
Pittsburgh Penguins draft picks
SaiPa players
Sudbury Wolves players
Toledo Goaldiggers players |
https://en.wikipedia.org/wiki/Mood%2092.0%20FM | Mood FM is a radio station broadcasting in Amman, Jordan. Mood FM is part of Seagulls Broadcast Ltd. and broadcasts on the 92.0 and 91.5 MHz frequency.
External links
Official website
Radio stations in Jordan
Mass media in Amman |
https://en.wikipedia.org/wiki/HLA-DR52 | HLA-DR52 is an HLA-DR serotype that recognizes gene products of HLA-DRB3 locus. Three allele groups can produce 35 isoforms.
DRB3, DRB4, and DRB5 are minor DR beta-encoding loci, and they have been recognized as having distinct evolution, having diverged from DRB1 around 4 million years ago.
The DRB3 locus is only apparent in a small subset of DR haplotypes, and most individuals lack DRB3.
Alleles
Associated diseases
DR52 serotype is positively associated with systemic sclerosis, inflammatory myopathies, inclusion body myositis,
DRB3*01 is positively associated with sarcoidosis, Grave's Disease, pulmonary sarcoidosis,
DRB3*01:01:DRB1*03:01 is linked to Lofgren's syndrome
DRB3*02:02 is also linked to Grave's disease, serum IgG antibodies to Chlamydia pneumoniae with essential hypertension, acute necrotizing encephalopathy
DRB3*03:01 is weakly associated with anticardiolipin antibodies in SLE
DRB3*03:01:DRB1*13:02 may be associated with Crohn's disease
DRB1 linkage
HLA-DRB3 is linked to these HLA-DR serotypes and DRB1 allele groups:
HLA-DR3 - DRB1*03
HLA-DR5 -
HLA-DR11 - DRB1*11
HLA-DR12 - DRB1*12
HLA-DR6 -
HLA-DR13 - DRB1*13
HLA-DR14 - DRB1*14
Rarely HLA-DR8 - DRB1*08
HLA-DR52 - Sjögren syndrome
References
HLA-DR haplotypes |
https://en.wikipedia.org/wiki/Caproni%20Ca.111 | The Caproni Ca.111 was a long-range reconnaissance aircraft and light bomber produced in Italy during the 1930s. It was a derivative of the Ca.101.
Design and development
A robust and simple aircraft, it was meant to be used in harsh conditions with minimal support. It was designed by the engineer Rodolfo Verduzio of Gianni Caproni in 1931, and first flew in February 1932 as MM 205.
This aircraft was a high-wing monoplane, built with a robust but simple structure consisting of a tubular steel skeleton with a fabric and wood skin. Derived from the earlier Ca.101, it used a different engine. The fuselage was of square section, and the wing was practically rectangular, with the extremities sloped and the ailerons running the whole length of the trailing edge. Steel tubing was also used for the undercarriage. This was fixed and had a complex structure that had two legs supported by several steel tubes between the fuselage and the wings.
The crew consisted of three men. The pilot, a co-pilot/observer and a flight engineer/gunner.
The main innovation was the engine. While the previous Ca.101 had three units, the newer type had only one. This was a risk because the engines of the time were not very reliable. It seems that the gamble paid off as the Ca.111 was faster than the three-engine Ca.101 and even the Ca.133. The engine was a water-cooled Isotta Fraschini Asso 750RC 18-cylinder in a 'W' layout. The first examples were equipped with a four-blade wooden propeller. Later mode |
https://en.wikipedia.org/wiki/Hank%20Klibanoff | Hank Klibanoff (born March 26, 1949, in Florence, Alabama) is an American journalist, now a professor at Emory University. He and Gene Roberts won the 2007 Pulitzer Prize for History for the book The Race Beat: The Press, the Civil Rights Struggle, and the Awakening of a Nation.
Early life and education
Hank Klibanoff was born and raised in Florence, Alabama. He got an early start in journalism delivering newspapers by bicycle. He graduated from Coffee High School in Florence and attended Washington University in St. Louis, where he studied under Howard Nemerov and received his B.A. in English. He subsequently received a master's degree in journalism from the Medill School of Northwestern University.
Career
He was managing editor of the Atlanta Journal-Constitution until June 24, 2008, when he stepped down. He had been deputy managing editor for The Philadelphia Inquirer, where he worked for 20 years. He had also been a reporter for six years in Mississippi and three years at The Boston Globe.
Klibanoff is currently the director of the journalism program at Emory University in Atlanta, Georgia, as well as the project managing editor of the Civil Rights Cold Case Project.
He hosts a podcast called "Buried Truths" about racial tensions in Georgia during and after the 1948 election. The podcast won a 2018 Peabody Award.
Family
Klibanoff is father to 3 girls, Eleanor, Caroline and Corinne; he is married to Laurie Leonard.
References
External links
1949 births
People fr |
https://en.wikipedia.org/wiki/HLA-DRB4 | Major histocompatibility complex, class II, DR beta 4, also known as HLA-DRB4, is a human gene.
Function
The protein encoded by this gene belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen-presenting cells (APC: B lymphocytes, dendritic cells, macrophages).
Gene structure and polymorphisms
The beta chain is approximately 26-28 kDa. It is encoded by 6 exons, exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.
Gene expression
DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.
See also
HLA-DR
References
Further reading |
https://en.wikipedia.org/wiki/N-Acetylglycinamide | N-Acetylglycinamide is a glycine derivative.
See also
Acetylglycinamide chloral hydrate
N-Acetylglycine
References
Acetamides |
https://en.wikipedia.org/wiki/List%20of%20Major%20League%20Baseball%20career%20on-base%20percentage%20leaders | In baseball statistics, on-base percentage (OBP) is a measure of how often a batter reaches base for any reason other than a fielding error, fielder's choice, dropped or uncaught third strike, fielder's obstruction, or catcher's interference. OBP is calculated in Major League Baseball (MLB) by dividing the sum of hits, walks, and times hit by a pitch by the sum of at-bats, walks, times hit by pitch and sacrifice flies. A hitter with a .400 on-base percentage is considered to be great and rare; only 61 players in MLB history with at least 3,000 career plate appearances (PA) have maintained such an OBP. Left fielder Ted Williams, who played 19 seasons for the Boston Red Sox, has the highest career on-base percentage, .4817, in MLB history. Williams led the American League (AL) in on-base percentage in twelve seasons, the most such seasons for any player in the major leagues. Barry Bonds led the National League (NL) in ten seasons, a NL record. Williams also posted the then-highest single-season on-base percentage of .5528 in 1941, a record that stood for 61 years until Bonds broke it with a .5817 OBP in 2002. Bonds broke his own record in 2004, setting the current single-season mark of .6094.
Players are eligible for the Hall of Fame if they have played at least 10 major league seasons, have been either retired for five seasons or deceased for six months, and have not been banned from MLB. These requirements leave 6 living players ineligible who have played in the past 5 seaso |
https://en.wikipedia.org/wiki/Lagynias | Lagynias was a genus of flowering plants in the family Rubiaceae but is no longer recognized. In 2005, it was sunk into synonymy with Vangueria, based on a phylogenetic study of DNA sequences.
Species
Lagynias dryadum (S.Moore) Robyns
Lagynias lasiantha (Sond.) Bullock
Lagynias monteiroi (Oliv.) Bridson
Lagynias pallidiflora Bullock
Lagynias rufescens (E.A.Bruce) Verdc.
See also
Cuviera
References
External links
World Checklist of Rubiaceae
Historically recognized Rubiaceae genera
Flora of Africa
Vanguerieae
Taxonomy articles created by Polbot |
https://en.wikipedia.org/wiki/Lastreopsis | Lastreopsis, known as shieldfern, is a genus of ferns in the family Dryopteridaceae, subfamily Elaphoglossoideae, in the Pteridophyte Phylogeny Group classification of 2016 (PPG I).
Species
, the Checklist of Ferns and Lycophytes of the World accepted the following species:
Lastreopsis amplissima (C.Presl) Tindale
Lastreopsis davalliaeformis (Tardieu) Tardieu
Lastreopsis davallioides (Brack.) Tindale
Lastreopsis decomposita (R.Br.) Tindale
Lastreopsis dissecta (C.T.White & Goy) Labiak, Sundue & R.C.Moran
Lastreopsis hispida (Sw.) Tindale
Lastreopsis killipii (C.Chr. & Maxon) Tindale
Lastreopsis marginans (F.Muell.) D.A.Sm. & Tindale ex Tindale
Lastreopsis nephrodioides (Baker) Tindale
Lastreopsis poecilophlebia (Hook.) Labiak, Sundue & R.C.Moran
Lastreopsis silvestris D.A.Sm. ex Tindale
Lastreopsis squamifera (C.Chr.) Lellinger
Lastreopsis subrecedens Ching
Lastreopsis subsericea (Mett.) Tindale
Lastreopsis subsparsa (Alderw.) Tindale
Lastreopsis tenera (R.Br.) Tindale
Lastreopsis tripinnata (F.Muell. ex Benth.) Labiak, Sundue & R.C.Moran
Lastreopsis velutina (A.Rich.) Tindale
Lastreopsis vieillardii (Mett.) Tindale
Lastreopsis walleri Tindale
Lastreopsis wurunuran (Domin) Tindale
References
Dryopteridaceae
Fern genera
Taxonomy articles created by Polbot
Taxa named by Ren-Chang Ching |
https://en.wikipedia.org/wiki/Leptochilus%20%28plant%29 | Leptochilus is a fern genus in the family Polypodiaceae, subfamily Microsoroideae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I).
Taxonomy
A molecular phylogenetic study of the subfamily Microsoroideae in 2019 suggested that the genus was monophyletic, being sister to Microsorum, together forming one of the three main clades in the subfamily:
Species
The Pteridophyte Phylogeny Group classification of 2016 (PPG I) suggests that the genus contains about 10 species. , the Checklist of Ferns and Lycophytes of the World noted that the species circumscription was "fairly controversial and fluctuating", and accepted 34 species and hybrids:
Leptochilus axillaris (Cav.) Kaulf.
Leptochilus bolsteri (Copel.) Parris
Leptochilus cantoniensis (Baker) Ching
Leptochilus chilangensis (V.N.Tu) Liang Zhang & Li Bing Zhang
Leptochilus chingii Liang Zhang & Li Bing Zhang
Leptochilus chittagongensis Fraser-Jenk. & Gias
Leptochilus decurrens Blume
Leptochilus digitatus (Baker) Noot.
Leptochilus dissimilialatus (Bonap.) Liang Zhang & Li Bing Zhang
Leptochilus dolichopterus (Copel.) Fraser-Jenk. & Amoroso
Leptochilus ellipticus (Thunb.) Noot.
Leptochilus evrardii (Tardieu) Liang Zhang & Li Bing Zhang
Leptochilus flexilobus (Christ) Liang Zhang & Li Bing Zhang
Leptochilus fluviatilis (Lauterb.) Liang Zhang & Li Bing Zhang
Leptochilus hemionitideus (C.Presl) Noot.
Leptochilus henryi (Baker) X.C.Zhang
Leptochilus heterophyllus (S.K.Wu & P.K.Lôc) comb. ined.
Leptochilus |
https://en.wikipedia.org/wiki/Eugen%20Netto | Eugen Otto Erwin Netto (30 June 1848 – 13 May 1919) was a German mathematician. He was born in Halle and died in Giessen.
Netto's theorem, on the dimension-preserving properties of continuous bijections, is named for Netto. Netto published this theorem in 1878, in response to Georg Cantor's proof of the existence of discontinuous bijections between the unit interval and unit square. His proof was not fully rigorous, but its errors were later repaired.
Works
Substitutionentheorie und ihre Anwendung auf die Algebra. Teubner 1882.
Theory of Substitutions and Its Applications to Algebra. Ann Arbor, Mich. 1892.
Die Determinanten. Teubner, 1910.
Die Determinanten. Teubner, 2nd edition 1925.
Lehrbuch der Combinatorik. Teubner, 1901, 2nd edition 1927.
Elementare Algebra. Teubner 1904.
Gruppen- und Substitutionentheorie. Leipzig, Göschen, 1908.
Vorlesungen über Algebra. Erster Band. Teubner, 1896.
Vorlesungen über Algebra. Zweiter Band. Teubner, 1900.
Netto: Kombinatorik. Enzyklopädie der Mathematischen Wissenschaften, Bd.1, 1898.
Netto: Rationale Funktionen einer Veränderlichen; ihre Nullstellen. Enzyklopädie Math.Wiss., Bd.1, 1899.
Netto: Rationale Funktionen mehrerer Veränderlichen. Enzyklopädie Mathem.Wiss., Bd.1, 1899.
References
1848 births
1919 deaths
19th-century German mathematicians
People from Halle (Saale)
People from the Province of Saxony
20th-century German mathematicians |
https://en.wikipedia.org/wiki/Rescue%20and%20salvage%20ship | Rescue and salvage ships (hull classification symbol ARS) are a type of military salvage tug. They are tasked with coming to the aid of stricken vessels. Their general mission capabilities include combat salvage, lifting, towing, retraction of grounded vessels, off-ship firefighting, and manned diving operations. They were common during World War II.
List of rescue and salvage ships of the United States Navy by class
The following ship classes have been designated under the ARS hull classification symbol in United States Navy Service.
Lapwing-class minesweeper conversions
The earliest designated United States Navy salvage ships (ARS) were converted s. Ships of this type were operated by the United States Navy as salvage ships from June 1941 until USS Viking was decommissioned and scrapped in 1953.
Diver class
The United States Navy operated s (ARS) from October 1943 until the last example was decommissioned in July 1979. Several ships of this class were converted to other uses, and USS Shackle remained in service as the 213' United States Coast Guard Cutter until March 2011.
(Converted to USCGC Escape (WMEC-6))
(Converted to )
(Converted to USNS Chain (T-AGOR-17))
(Converted to USCGC Yocona (WAT-168))
(Converted to USNS Argo (T-AGOR-18))
Miscellaneous civilian vessel conversions
Several ships were converted and redesignated as salvage ships (ARS) during World War II.
(canceled)
Anchor class
The United States Navy operated s (ARS) from Oc |
https://en.wikipedia.org/wiki/HLA-DRB5 | HLA class II histocompatibility antigen, DRB5 beta chain is a protein that in humans is encoded by the HLA-DRB5 gene.
Function
The protein encoded by this gene belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen-presenting cells (APC: B lymphocytes, dendritic cells, macrophages).
Gene structure and polymorphisms
The beta chain is approximately 26-28 kDa. It is encoded by 6 exons, exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.
Gene expression
DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. The presence of DRB5 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.
See also
HLA-DR
Referen |
https://en.wikipedia.org/wiki/Micropolypodium | Micropolypodium is a genus of ferns in the family Polypodiaceae, subfamily Grammitidoideae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I).
It is native to China, Japan, and the Philippines.
Species
Neotropical (the Americas) species formerly placed in the genus have been reclassified to Moranopteris.
Micropolypodium now contains the following species according to the Checklist of Ferns and Lycophytes of the World :
Micropolypodium okuboi (Yatabe) Hayata
Micropolypodium pulogense (Copel.) A.R.Sm.
Micropolypodium sikkimense (Hieron.) X.C.Zhang
References
Polypodiaceae
Fern genera
Taxonomy articles created by Polbot |
https://en.wikipedia.org/wiki/HLA-DR18 | HLA-DR18 (DR18) is a HLA-DR serotype that recognizes the DRB1*0302 and *0303 gene products. Compared to DR17 which is found at high frequency in Western Europe, DR18 is found more in SE Europe and Central Asia.
Serology
DR18 recognizes the DRB1*0302 and *0303, the thoroughness of recognition is fair, but better than DR3.
Disease associations
DR18 seropositivity is associated with rheumatoid polyarthritis
DRB1*0302 is positively associated with juvenile diabetes, nuclear helicase Mi-2 autoantibodies in inflammatory inclusion body myositis.
Genetic Linkage
HLA-DR18 is genetically linked to DR52 and HLA-DQ2 serotypes. These serotypes
are the result of gene products from the HLA-DRB3* and HLA DQA1*0501 and HLA DQB1*0201 alleles.
References
3 |
https://en.wikipedia.org/wiki/HLA-DR17 | HLA-DR17 (DR17) is an HLA-DR serotype that recognizes the DRB1*0301 and *0304 gene products. DR17 is found at high frequency in Western Europe (such as Western Ireland, N. Spain, Sardinia). DR17 is part of the broader antigen group HLA-DR3 and is very similar to the group HLA-DR18.
Serology
DR17 recognizes the DRB1*0301, *0304 alleles.
Disease associations
By serotype
DR17 is associated with non-chronic sarcoidosis, infantile spasm/epilepsy, rabies vaccine-induced autoimmune encephalomyelitis and cardiovascular hypertrophy in subjects with arterial hypertension People with DR17 show a tendency toward benzylpenicilloyl allergies.
By allele
DRB1*0301: diabetes mellitus type 1, myositis, early onset Graves disease, type 1 autoimmune hepatitis, inflammatory inclusion body myositis. In autoimmune hepatitis,
DRB1*0301 correlates with more severe and difficult to treat disease.
By haplotype
DRB1*0301:DQA1*05:DQB1*0201 is associated with diabetes mellitus type 1, ovarian cancer, non-thymomic myasthenia gravis, idiopathic inflammatory myopathies, non-cancer associated Lambert-Eaton myasthenic syndrome and sarcoidosis
By phenotype
The DRB1*0301/DRB1*1501 heterozygote is linked to primary Sjögren's syndrome
Genetic Linkage
HLA-DR17 is genetically linked to DR52 and HLA-DQ2 serotypes. These serotypes
are the result of gene products from the HLA-DRB3* and HLA DQA1*0501 and HLA DQB1*0201 alleles.
DRB1*0301 is frequently within by the "Super-B8" or ancestral HLA haplotype:
A*0101 |
https://en.wikipedia.org/wiki/List%20of%20Major%20League%20Baseball%20career%20slugging%20percentage%20leaders | In baseball statistics, slugging percentage (SLG) is a measure of the batting productivity of a hitter. It is calculated as total bases divided by at bats. Unlike batting average, slugging percentage gives more weight to extra-base hits with doubles, triples, and home runs, relative to singles. Plate appearances ending in walks are specifically excluded from this calculation, as an appearance that ends in a walk is not counted as an at bat.
Babe Ruth is the all-time leader with a career slugging percentage of .6897. Ted Williams (.6338), Lou Gehrig (.6324), Mule Suttles (.6179), Turkey Stearnes (.6165), Oscar Charleston (.6145), Jimmie Foxx (.6093), Barry Bonds (.6069), and Hank Greenberg (.6050) are the only other players with a career slugging percentage over .600.
Key
List
Stats updated as of October 1, 2023.
Notes
Sources
Slugging percentage 5
Major League Baseball statistics |
https://en.wikipedia.org/wiki/Neocheiropteris | Neocheiropteris is a genus of ferns in the family Polypodiaceae, subfamily Microsoroideae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I).
Taxonomy
A molecular phylogenetic study in 2019 suggested that Neocheiropteris was one of a group of closely related genera in the subfamily Microsoroideae, a group the authors termed "Lepisorus sensu lato". It species were embedded in a clade in which none of the genera appeared to be monophyletic:
Species
, the Checklist of Ferns and Lycophytes of the World recognized the following species, while noting that the distinction from Neolepisorus was not clear:
Neocheiropteris ensata (Thunb.) Ching
Neocheiropteris ovata (Wall. ex Hook. & Grev.) Fraser-Jenk.
Neocheiropteris palmatopedata (Baker) Christ
Neocheiropteris triglossa (Baker) Ching
Plants of the World Online submerges Neolepisorus into Neocheiropteris, although placing some species that the Checklist of Ferns and Lycophytes of the World accepts in Neolepisorus in Microsorum.
References
Polypodiaceae
Fern genera
Taxonomy articles created by Polbot |
https://en.wikipedia.org/wiki/HLA-DR16 | HLA-DR16(DR16) is a HLA-DR serotype that recognizes the DRB1*1601, *1602 and *1604 gene products. DR16 is found in the Mediterranean at modest frequencies. DR16 is part of the older HLA-DR2 serotype group which also contains the similar HLA-DR15 antigens.
Alleles
Disease associations
DR16 is associated with Chaga's cardiomyopathy, rheumatic heart disease, coronary artery ectasia, and chronic discoid lupus erythematosus.
DRB1*1601 is associated with tuberculosis risk
DRB1*1602: Juvenile rheumatoid arthritis, rheumatic heart disease, Takayasu arteritis, systemic sclerosis (SSc) & anti-DNA topoisomerase I (anti-topo I) antibody, melioidosis (Burkholderia pseudomallei infection)
Extended linkage
DRB1*1601:DQA1*0102:DQB1*0502 haplotype is associated with tubeculousis risk
*1602:DQA1*0102:DQB1*0502 haplotype: graves disease, cervical cancer (human papilloma virus infection), scleroderma
*1602:DQA1*05:DQB1*0301 haplotype: rheumatic heart disease, systemic sclerosis
Genetic Linkage
HLA-DR16 is genetically linked to HLA-DR51 and HLA-DQ5 serotypes.
References
2 |
https://en.wikipedia.org/wiki/2N | 2N or 2-N may refer to:
2N or 2°N, the 2nd parallel north latitude
MI 2N, a type of electric multiple unit running on the French RER rail network
2N, a prefix labelling certain JEDEC transistors, notably the 2N2222
2N, an indicator of a redundancy level in (for example) an uninterruptible power supply configuration
Powers of 2 (2n)
In genetics, 2n = x refers to a diploid chromosome number of x
NJ 2-N; see New Jersey Route 17
MI 2N series double-decker train; see RER A
HP 2N, ISO/IEC 8859-2 character set on printers by Hewlett-Packard
See also
N2 (disambiguation) |
https://en.wikipedia.org/wiki/HLA-DR15 | HLA-DR15 (DR15) is a HLA-DR serotype that recognizes the DRB1*1501 to *1505 and *1507 gene products. DR15 is found at high levels from Ireland to Central Asia. DR15 is part of the older HLA-DR2 serotype group which also contains the similar HLA-DR16 antigens.
Serology
Serotypes are unknown for the following alleles: DRB1*1506, *1508 to *1516, *1518 to *1522.
DRB1*1517N is a null.
Alleles
Disease associations
DR15 is positively associated Goodpasture syndrome, early age onset multiple sclerosis, pernicious anaemia, sarcoidosis, hypocretin deficiency associated narcolepsy
and a predisposition for postmenopausal osteoporosis.
DRB1*1501 is positively associated with Goodpasture syndrome, juvenile rheumatoid arthritis, allergic bronchopulmonary aspergillosis, multiple sclerosis, systemic lupus erythematosus, cervical cancer (human papillomavirus infection), Sjögren syndrome associated with systemic lupus erythematosus, and intermediate uveitis.
DRB1*1502 is associated with systemic lupus erythematosus, systemic sclerosis (SSc) & anti-topoisomerase antibodies.
DRB1*1503 is associated with Chaga's cardiomyopathy, allergic bronchopulmonary aspergillosis, multiple sclerosis, cervical cancer (human papillomavirus infection).
Extended linkage
DRB1*15:DQA1*0102:DQB1*0602 haplotype us associated with cervical cancer risk in (human papillomavirus infection)
DRB1*1502:DQA1*????:DQB1*0501 haplotype is associated with systemic lupus erythematosus
Genetic Linkage
HLA-DR15 is genet |
https://en.wikipedia.org/wiki/Pecluma | Pecluma is a genus of ferns in the family Polypodiaceae, subfamily Polypodioideae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I). They are called rockcap ferns.
Species
, Checklist of Ferns and Lycophytes of the World accepted the following species:
Pecluma absidata (A.M.Evans) M.G.Price
Pecluma alfredii (Rosenst.) M.G.Price
Pecluma atra (A.M.Evans) M.G.Price
Pecluma barituensis O.G.Martínez & de la Sota
Pecluma bermudiana (A.M.Evans) M.G.Price
Pecluma bourgeauana (E.Fourn.) L.A.Triana
Pecluma camptophyllaria (Fée) M.G.Price
Pecluma chiapensis (A.M.Evans & A.R.Sm.) M.G.Price
Pecluma chnoophora (Kunze) Salino & F.C.Assis
Pecluma choquetangensis (Rosenst.) M.G.Price
Pecluma consimilis (Eaton ex Mett.) M.G.Price
Pecluma curvans (Mett.) M.G.Price
Pecluma dispersa (A.M.Evans) M.G.Price
Pecluma divaricata (E.Fourn.) Mickel & Beitel
Pecluma dulcis (Poir.) F.C.Assis & Salino
Pecluma eurybasis (C.Chr.) M.G.Price
Pecluma ferruginea (M.Martens & Galeotti) M.G.Price
Pecluma filicula (Kaulf.) M.G.Price
Pecluma funicula (Fée) M.G.Price
Pecluma hartwegiana (Hook.) F.C.Assis & Salino
Pecluma hoehnei (A.Samp.) Salino
Pecluma hygrometrica (Splitg.) M.G.Price
Pecluma imbeana (Brade) Salino
Pecluma insularis (Brade) Salino
Pecluma liebmannii (C.Chr.) A.R.Sm. & Carv.-Hern.
Pecluma longepinnulata (E.Fourn.) F.C.Assis & Salino
Pecluma macedoi (Brade) M.Kessler & A.R.Sm.
Pecluma oranense (de la Sota) de la Sota
Pecluma paradiseae (Langsd. & Fisch.) M.G.Price
Pecluma |
https://en.wikipedia.org/wiki/Pennantia%20baylisiana | Pennantia baylisiana, commonly known as Three Kings kaikōmako or (Māori), is a species of plant in the family Pennantiaceae (Icacinaceae in older classifications). It is endemic to Manawatāwhi / Three Kings Islands, around northwest of Cape Reinga, New Zealand. At the time of its discovery just one plant remained. This single tree grows on a scree slope inaccessible to browsing goats, and has been called "the world's loneliest tree". The species was discovered in 1945 by botanist Geoff Baylis and described in 1948, although it took decades before it was it was fully accepted as a distinct species of Pennantia. Although the only wild tree is female, it was successfully propagated from cuttings in the 1950s, one of which was induced to self-pollinate in 1985. Subsequent seed-grown plants have themselves set seeds, and the species has been replanted on the island, the adjoining mainland, and in public and private gardens around New Zealand.
Description
Pennantia baylisiana is a shrubby, multi-trunked tree with a broad crown, unlike the three other species in the genus Pennantia. It does not have a divaricating juvenile form, unlike the other New Zealand Pennantia species kaikōmako (P. corymbosa). It grows to a height of 5 m in the wild, though has been recorded reaching 8 m in cultivation. It has pale greyish-brown bark and branchlets that are covered with lenticels.
It has leathery, green, egg-shaped alternate leaves around 12–16 by 7–10 cm. Adult leaves have smooth margin |
https://en.wikipedia.org/wiki/Pennantia | Pennantia is the sole genus in the plant family Pennantiaceae. In older classifications, it was placed in the family Icacinaceae. Most authorities have recognised three or four species, depending on whether they recognised Pennantia baylisiana as a separate species from Pennantia endlicheri. British-born botanist David Mabberley has recognised two species.
The species are small to medium, sometimes multi-trunked trees. Leaves are alternate, leathery, and with entire or sometimes toothed margins. Inflorescences are terminal and flowers are functionally unisexual; the species are more or less dioecious.
Pennantia species grow naturally in New Zealand, Norfolk Island, and eastern Australia. In Australia, P. cunninghamii grows across a broad latitudinal natural range (nearly ), from the south coast of New South Wales northwards through to north eastern Queensland.
The genus name, Pennantia, is in honor of Thomas Pennant, an 18th century Welsh zoologist and author.
Species
The following four species were recognised by New Zealand botanists Rhys O. Gardner and Peter J. de Lange in 2002.
Pennantia baylisiana, – Three Kings Islands
Pennantia corymbosa , 'kaikōmako' – New Zealand
Pennantia cunninghamii , 'brown beech' – NSW, Qld, Australia
Pennantia endlicheri – Norfolk Island
References
External links
Missouri Botanical Garden Website−Mobot.org: Pennantiaceae + Pennantia
Pennantiaceae
Apiales genera
Taxonomy articles created by Polbot
Dioecious plants |
https://en.wikipedia.org/wiki/Biomax%20Informatics | Biomax Informatics is a Munich-based software company specializing in research software for bioinformatics. Biomax was founded in 1997 and has its roots in the Munich Information Center for Protein Sequences (MIPS). The company's customer base consists of companies and research organizations in the areas of drug discovery, diagnostics, fine chemicals, food and plant production. In addition to exclusive software tools, Biomax Informatics provides services and curated knowledge bases.
In September 2007, Biomax Informatics acquired the Viscovery software business of the Austrian data mining specialist Eudaptics Software.
Biomax Informatics and Sophic Systems Alliance Inc. (USA) participate in the Cancer Gene Data Curation Project with the National Cancer Institute (USA). This project maintains a public data set of cancer-related genes and drugs. This data set has been integrated with the NCI's (cancer Bioinformatics Infrastructure Objects) domain model which is part of the CaBIG Integrative Cancer Research (ICR) workspace. This Cancer Gene Index can be obtained separately from an NCI web site.
Products
BioXM Knowledge Management Environment
BioRS Integration and Retrieval System
Pedant-Pro Sequence Analysis Suite
Subsidiaries
Viscovery Software GmbH
See also
Bioinformatics
Bioinformatics companies
References
External links
Biomax Informatics official homepage
Viscovery Software official homepage
Cancer Gene Data Curation Project
Research support companies
Bioi |
https://en.wikipedia.org/wiki/Plagiogyria | Plagiogyria is a genus of ferns, the only genus in family Plagiogyriaceae in the Pteridophyte Phylogeny Group classification of 2016 (PPG I). Alternatively, the family may be treated as the subfamily Plagiogyrioideae of a very broadly defined family Cyatheaceae, the placement used for the genus in Plants of the World Online .
Ferns of this genus present two kind of fronds, the fertile ones longer than the sterile. These ferns are found on forest soils in mountainous areas of tropical and subtropical regions. Most are native to Asia; one is found in the Americas.
Phylogeny
, Plants of the World Online accepted the following species. Phylogeny of Plagiogyria
Other species include:
P. assurgens Christ
P. falcata Copel.
P. ×neointermedia]] Nakaike
P. pycnophylla (Kunze) Mett.
[[Plagiogyria × sessilifolia|P. ×sessilifolia Nakaike
References
Cyatheales
Taxonomy articles created by Polbot
Fern genera |
https://en.wikipedia.org/wiki/Polybotrya | Polybotrya is a genus of ferns in the family Dryopteridaceae, subfamily Polybotryoideae, in the Pteridophyte Phylogeny Group classification of 2016 (PPG I).
Species
, the Checklist of Ferns and Lycophytes of the World accepted the following species:
Polybotrya aequatoriana R.C.Moran
Polybotrya alata R.C.Moran
Polybotrya alfredii Brade
Polybotrya altescandens C.Chr.
Polybotrya andina C.Chr.
Polybotrya appressa R.C.Moran
Polybotrya attenuata R.C.Moran
Polybotrya aureisquama A.Rojas
Polybotrya bipinnata A.Rojas
Polybotrya botryoides (Baker) C.Chr.
Polybotrya canaliculata Klotzsch
Polybotrya caudata Kunze
Polybotrya crassirhizoma Lellinger
Polybotrya cylindrica Kaulf.
Polybotrya espiritosantensis Brade
Polybotrya fractiserialis (Baker) J.Sm.
Polybotrya glandulosa Mett. ex Kuhn
Polybotrya gomezii R.C.Moran
Polybotrya goyazensis Brade
Polybotrya gracilis Brade
Polybotrya hickeyi R.C.Moran
Polybotrya insularis A.Rojas
Polybotrya latisquamosa R.C.Moran
Polybotrya lechleriana Mett.
Polybotrya lourteigiana Lellinger
Polybotrya matosii Canestraro & Labiak
Polybotrya osmundacea Humb. & Bonpl. ex Willd.
Polybotrya pilosa Brade
Polybotrya pittieri Lellinger
Polybotrya polybotryoides (Baker) Christ
Polybotrya pubens Mart. ex Kunze
Polybotrya puberulenta R.C.Moran
Polybotrya semipinnata Fée
Polybotrya serratifolia (Fée) Klotzsch
Polybotrya sessilisora R.C.Moran
Polybotrya sorbifolia Mett. ex Kuhn
Polybotrya speciosa Schott
Polybotrya stolzei R.C.Moran
Polybotrya suberecta (Baker) C.Chr.
R |
https://en.wikipedia.org/wiki/Statistics%20and%20Registration%20Service%20Act%202007 | The Statistics and Registration Service Act 2007 (c 18) is an Act of the Parliament of the United Kingdom which established the UK Statistics Authority (UKSA). It came into force in April 2008. Sir Michael Scholar was appointed as the first Chair of the UKSA.
The Act established the UK Statistics Authority as a non-ministerial department that employs the National Statistician. The National Statistician has an office to support them, the Office for National Statistics.
References
External links
Guide to the Act from the Office for National Statistics
United Kingdom Acts of Parliament 2007
Office for National Statistics |
https://en.wikipedia.org/wiki/P87PIKAP | Within molecular and cell biology, p87PIKAP is a regulatory subunit of the type IB Phosphoinositide 3-Kinase p110γ that is highly expressed in the heart and is present in dendritic cells, macrophages, and neutrophils.
It is also referred to as p84 and p87. Some studies have found P87PIKAP to have a role in carcinogenesis.
References |
https://en.wikipedia.org/wiki/HLA-DR13 | HLA-DR13(DR13) is a HLA-DR serotype that recognizes the DRB1*1301 to *13082, *1310 and some other *13 gene products. DR13 serotype is a split antigen of the older HLA-DR6 serotype group which also contains the similar HLA-DR14 antigens.
Alleles
Serotypes are unknown the following alleles: DRB1*1309, *1315 to *1379
DRB1*13 allele group
81 Alleles: 74 proteins
DR13 (weak or no DR6) Serotype: *1301, *1302, *1304, *1306, *1307, *1310, *1312 to *1314
DR6 (weak DR13) Serotype: *1308
DR13&Other serotypes: *1303, *1305, *1311,
Serotype unknown: *1309, *1315 to *1374
Disease associations
DRB1*1302 is linked to early childhood myastenia gravis. Alleles of DR13 along with immunization for hepatitis B and C are most protective against the disease.
Extended linkage
DRB1*1302:DQA1*0102:DQB1*0604 Early childhood myastenia gravis
Genetic Linkage
HLA-DR13 is genetically linked to DR52 and HLA-DQ6 (HLA-DQ1) serotypes.
References
6 |
https://en.wikipedia.org/wiki/Bombesin-like%20receptor%203 | The bombesin receptor subtype 3 also known as BRS-3 or BB3 is a protein which in humans is encoded by the BRS3 gene.
Function
Mammalian bombesin-like peptides are widely distributed in the central nervous system as well as in the gastrointestinal tract, where they modulate smooth-muscle contraction, exocrine and endocrine processes, metabolism, and behavior. They bind to G protein-coupled receptors on the cell surface to elicit their effects. Bombesin-like peptide receptors include gastrin-releasing peptide receptor, neuromedin B receptor, and bombesin-like receptor-3 (BRS3; this article).
BB3 is a G protein-coupled receptor. BB3 only interacts with known naturally occurring bombesin-related peptides with low affinity and therefore, as it has no natural high-affinity ligand, is classified as an orphan receptor.
References
Further reading
External links
G protein-coupled receptors |
https://en.wikipedia.org/wiki/Neuromedin%20B%20receptor | The neuromedin B receptor (NMBR), now known as BB1 is a G protein-coupled receptor whose endogenous ligand is neuromedin B. In humans, this protein is encoded by the NMBR gene.
Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue.
References
Further reading
External links
G protein-coupled receptors |
https://en.wikipedia.org/wiki/HLA-DR14 | HLA-DR14(DR14) is a HLA-DR serotype that recognizes the DRB1*1401 to *1408, *1410 to *1418, and other *14 gene products. DR14 serotype is a split antigen of the older HLA-DR6 serotype group which also contains the similar HLA-DR13 antigens.
Alleles
Serotypes are unknown the following alleles: DRB1**1409, *1419 to *1462
Disease associations
DRB1*1402: juvenile rheumatoid arthritis, increased longevity in Okinawans.
Extended linkage
DR*14:DQ5 haplotype: increased risk for non-AChR autoantibodies in myasthenia gravis.
Genetic Linkage
HLA-DR13 is genetically linked to HLA-DR52 and HLA-DQ5 (HLA-DQ1) serotypes.
References
6 |
https://en.wikipedia.org/wiki/Gastrin-releasing%20peptide%20receptor | The gastrin-releasing peptide receptor (GRPR), now properly known as BB2 is a G protein-coupled receptor whose endogenous ligand is gastrin releasing peptide. In humans it is highly expressed in the pancreas and is also expressed in the stomach, adrenal cortex and brain.
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
The transcription factor CREB is a regulator of human GRP-R expression in colon cancer.
Activation MOR1D‐GRPR heteromers in the spinal cord mediate the common troublesome opioid-induced itch.
References
Further reading
External links
IUPHAR GPCR Database - BB2 receptor
G protein-coupled receptors |
https://en.wikipedia.org/wiki/Crystal%20Dragon | is a Japanese historical fantasy manga series written and illustrated by Yuuho Ashibe. Set in Ireland and Roman Britain, the story follows a black-haired girl named Arianrhod and her fight against Balor Evil-Eye, the Gothic warlord who destroyed her home tribe. Joining her in the fight are Henruda, the daughter of a Celtic chieftain, and Legion, the Silver Knight. Crystal Dragon began serialization in Akita Shoten's monthly (girls') manga magazine Bonita in 1981, later transferring to its sister magazine Mystery Bonita. The series went on hiatus from 2007 to 2014, during which Ashibe resumed her other long-running manga series, Bride of Deimos. It went on hiatus again in summer 2020 due to unspecified circumstances. In April 2021, Ashibe announced that the series is nearing its climax. Akita Shoten has published 30 (compiled volumes) of Crystal Dragon under the Bonita Comics imprint as of November 2020; the company also published 12 (paperback novel-sized volumes) under the Akita Bunko imprint from July 2003 to July 2007. Internationally, the series is licensed in Indonesia by Elex Media Komputindo.
References
1981 manga
Akita Shoten manga
Historical fantasy anime and manga
Shōjo manga |
https://en.wikipedia.org/wiki/Sodium%20sesquicarbonate | Sodium sesquicarbonate (systematic name: trisodium hydrogendicarbonate) Na3H(CO3)2 is a double salt of sodium bicarbonate and sodium carbonate (NaHCO3 · Na2CO3), and has a needle-like crystal structure. However, the term is also applied to an equimolar mixture of those two salts, with whatever water of hydration the sodium carbonate includes, supplied as a powder.
The dihydrate, Na3H(CO3)2 · 2H2O, occurs in nature as the evaporite mineral trona.
Due to concerns about the toxicity of borax which was withdrawn as a cleaning and laundry product, sodium sesquicarbonate is sold in the European Union (EU) as "Borax substitute". It is also known as one of the E number food additives E500(iii).
Uses
Sodium sesquicarbonate is used in bath salts, swimming pools, as an alkalinity source for water treatment, and as a phosphate-free product replacing the trisodium phosphate for heavy duty cleaning.
Sodium sesquicarbonate is used in the conservation of copper and copper alloy artifacts that corrode due to contact with salt (called "bronze disease" due to its effect on bronze). The chloride from salt forms copper(I) chloride. In the presence of oxygen and water, even the small amount of moisture in the atmosphere, the cuprous chloride forms copper(II) chloride and hydrochloric acid, the latter of which dissolves the metal and forms more cuprous chloride in a self-sustaining reaction that leads to the entire destruction of the object. Treatment with sodium sesquicarbonate removes coppe |
https://en.wikipedia.org/wiki/This%20Must%20Be%20the%20Place%20%28album%29 | This Must Be the Place is a 1985 album by British jazz rock duo Morrissey–Mullen.
Track listing
"A Tear for Crystal"
"Mean Time"
"This Must Be the Place"
"With You"
"Southend Pierre"
"Visions"
"All I Want to Do"
Personnel
Dick Morrissey - saxes
Jim Mullen - guitar
Noel McCalla - vocals
Chris Fletcher - percussion
Neal Wilkinson - drums
Pete Jacobsen - keyboards
Trevor Barry - bass
References
1985 albums
Morrissey–Mullen albums |
https://en.wikipedia.org/wiki/Saccoloma | Saccoloma is a fern genus in family Saccolomataceae. It is the only genus in the family in the Pteridophyte Phylogeny Group classification of 2016 (PPG I), but further investigation is needed. It is pantropical and its species are found in wet, shaded forest areas. Saccoloma species are characterized by an omega-shaped (Ω) vascular bundle in the cross-sections of their petioles. The common name soralpouch fern is used for Saccoloma.
Phylogeny
Saccoloma includes Orthiopteris in the Pteridophyte Phylogeny Group classification of 2016 (PPG I), with a total of 18 species. , Plants of the World Online accepts the following species (which may be based on a wider circumscription of the genus). Synonyms are taken from the Checklist of Ferns and Lycophytes of the World.
Phylogeny of Saccoloma
Other species include:
Saccoloma acuminatum (Rosenst.) Christenh. (syn. Orthiopteris acuminata (Rosenst.) Copel.)Saccoloma cicutarioides (Baker) Christenh. (syn. Orthiopteris cicutarioides (Baker) Copel.)Saccoloma firmum (Kuhn) C.Chr. (syn. Orthiopteris firma (Kuhn) Brownlie)Saccoloma henriettae (Baker) C.Chr. (syn. Orthiopteris henriettae (Baker) Copel.)Saccoloma laxum R.C.Moran & B.Øllg.Saccoloma membranaceum MickelSaccoloma moranii A.RojasSaccoloma quadripinnatum A.RojasSaccoloma samoense (Hovenkamp & T.T.Luong) Christenh. (syn. Orthiopteris samoensis Hovenk. & T. T. Luong)Saccoloma squamosum R.C.MoranSaccoloma tenue (Brack.) Mett. (syn. Orthiopteris tenuis (Brack.) Brownlie)Saccoloma trich |
https://en.wikipedia.org/wiki/ZEB2 | Zinc finger E-box-binding homeobox 2 is a protein that in humans is encoded by the ZEB2 gene. The ZEB2 protein is a transcription factor that plays a role in the transforming growth factor β (TGFβ) signaling pathways that are essential during early fetal development.
Function
ZEB2 (previously also known as SMADIP1, SIP1) and its mammalian paralog ZEB1 belongs to the Zeb family within the ZF (zinc finger) class of homeodomain transcription factors. ZEB2 protein has 8 zinc fingers and 1 homeodomain. The structure of the homeodomain shown on the right.
ZEB2 interacts with receptor-mediated, activated full-length SMADs. The activation of TGFβ receptors brings about the phosphorylation of intracellular effector molecules, R-SMADs. ZEB2 is an R-SMAD-binding protein and acts as a transcriptional corepressor. It is involved in the timing of the conversion of neuroepithelial cells into radial glial cells in early development, a mechanism thought to allow for the large differences in brain size between humans and other mammals.
ZEB2 transcripts are found in tissues differentiated from the neural crest such as the cranial nerve ganglia, dorsal root ganglia, sympathetic ganglionic chains, the enteric nervous system and melanocytes. ZEB2 is also found in tissues that are not derived from the neural crest, including the wall of the digestive tract, kidneys, and skeletal muscles.
Clinical significance
Mutations in the ZEB2 gene are associated with the Mowat–Wilson syndrome. This dis |
https://en.wikipedia.org/wiki/Pyrodictium | Pyrodictium is a genus in the family Pyrodictiaceae. It is a genus of submarine hyperthermophilic Archaea whose optimal growth temperature range is 80 to 105°C. They have a unique cell structure involving a network of cannulae and flat, disk-shaped cells. Pyrodictium are found in the porous walls of deep-sea vents where the temperatures inside get as high as 400°C, while the outside marine environment is typically 3°C. Pyrodictium is apparently able to adapt morphologically to this type of hot–cold habitat.
Genome structure
Much research has been done on the genetics of Pyrodictium in order to understand its ability to survive and even thrive in such extreme temperatures. The thermal stability of Pyrodictum occultum'''s isolate tRNA has been analyzed, indicating that modifications in the nucleosides allow the organism to withstand temperatures well over 100°C.
Cell structure and metabolism Pyrodictium cells have been studied by scientists in part because they are a model of thermal stability. The cells' structure is a flat, irregular disk, 300 to 2500 nanometres in diameter and up to 300 nanometres in width. The cells grow in unique flake-like shapes held together by a network of hollow cannulae (tubules). The cannulae branch out and connect with other cells, greatly extending their range. While the exact reason for this morphology is unknown, it is likely that the range of motion provided by the cannulae allow the cells to move freely when by the thermal energy from the |
https://en.wikipedia.org/wiki/Brian%20Whitehouse | Brian Whitehouse (8 September 1935 – 16 January 2017) was an English professional footballer who played as a forward for West Bromwich Albion, Norwich City, Wrexham, Crystal Palace, Charlton and Leyton Orient. He was top scorer for Palace in the 1965–1966 season with seven goals. After his retirement from playing in 1968, he undertook various coaching and scouting positions, and was briefly caretaker manager at West Bromwich Albion in 1975; he died in 2017, aged 81.
Whitehouse's debut came on 14 April 1956 at Portsmouth's Fratton Park as injury to Johnny Nicholls gave manager Vic Buckingham a chance to assess him across the final three games of the season.
References
External links
1935 births
2017 deaths
Footballers from West Bromwich
English men's footballers
West Bromwich Albion F.C. players
Norwich City F.C. players
Wrexham A.F.C. players
Crystal Palace F.C. players
Charlton Athletic F.C. players
Leyton Orient F.C. players
Tamworth F.C. players
English football managers
West Bromwich Albion F.C. managers
Manchester United F.C. non-playing staff
English Football League players
Men's association football forwards |
https://en.wikipedia.org/wiki/Tom%20Farndon | Thomas Farndon (11 September 1910 – 30 August 1935), was a British speedway rider who won the Star Riders' Championship in 1933 whilst with the Crystal Palace Glaziers.
Career
Born in Coventry, Farndon started his career at the Lythalls Lane track in Foleshill and later rode for the club based at Brandon Stadium, before a spell with the Crystal Palace Glaziers. He moved to New Cross Lambs with Palace promoter Fred Mockford in 1934.
Farndon was the British Individual Match Race Champion and was undefeated from 1934 until his death in 1935.
Film appearance
The speedway scenes from the 1933 film Britannia of Billingsgate were shot at Hackney Wick Stadium and featured some of the leading riders in Britain at the time including Farndon, Colin Watson, Arthur Warwick, Gus Kuhn, Claude Rye and Ron Johnson.
Death
Tom Farndon was killed after a crash on 28 August 1935 whilst racing at the New Cross Stadium in a second half scratch race final. He was involved in a collision with team-mate Ron Johnson, who clipped the safety fence and fell causing Farndon to crash into Johnson's bike. Farndon suffered a fractured skull and spine injury and was unconscious when he was transferred to the Miller General Hospital in Greenwich. Tom died two days later (on 30 August) in Miller General Hospital, Greenwich, without regaining consciousness.
Thousands lined the streets to see his funeral. An art deco memorial in the form of a motorbike racer, carved by local sculptor Richard Ormerod out of bl |
https://en.wikipedia.org/wiki/Active%20service%20unit | An active service unit (ASU; ) was a Provisional Irish Republican Army (IRA) cell of four to ten members, tasked with carrying out armed attacks. In 2002, the IRA had about 1,000 active members of which about 300 were in active service units.
In 1977, the IRA moved away from the larger conventional military organisational principle owing to its perceived security vulnerability. In place of the battalion structures, a system of two parallel types of unit within an IRA Brigade was introduced. Firstly, the old "company" structures were used to supply auxiliary members for support activities such as intelligence-gathering, acting as lookouts or moving weapons.
The bulk of attacks from 1977 onwards were the responsibility of a second type of unit, the ASU. To improve security and operational capacity these ASUs were smaller, tight-knit cells, usually consisting of five to eight members, for carrying out armed attacks. The ASU's weapons were controlled by a quartermaster under the direct control of the IRA leadership. By the late 1980s and early 1990s, it was estimated that the IRA had roughly 300 members in ASUs and approximately 450 serving in supporting roles.
The exception to this reorganisation was the South Armagh Brigade which retained its traditional hierarchy and battalion structure and used relatively large numbers of volunteers in its actions. Some operations, like the attack on Cloghogue checkpoint or the South Armagh sniper squads, involved as many as 20 volunteers, |
https://en.wikipedia.org/wiki/Methanohalobium | In taxonomy, Methanohalobium is a genus of the Methanosarcinaceae. Its genome has been sequenced. The genus contains one species, M. evestigatum.
The species are strictly anaerobic and live solely through the production of methane through the reduction of carbon dioxide with hydrogen or using methyl compounds as substrates. These species are only somewhat halophilic but extremely thermophilic.
See also
List of Archaea genera
References
Further reading
Scientific journals
Scientific books
Scientific databases
External links
Methanohalobium at BacDive - the Bacterial Diversity Metadatabase
Archaea genera
Euryarchaeota |
https://en.wikipedia.org/wiki/Clorindione | Clorindione is a vitamin K antagonist. It is a derivative of phenindione.
References
Further reading
Vitamin K antagonists
Chloroarenes
Indandiones |
https://en.wikipedia.org/wiki/Tectaria | Tectaria is a genus of fern in the family Tectariaceae, according to the Pteridophyte Phylogeny Group classification of 2016 (PPG I). Halberd fern is a common name for species in this genus.
Species
, the Checklist of Ferns and Lycophytes of the World recognized the following species and hybrids:
Tectaria acerifolia R.C.Moran
Tectaria acrocarpa (Ching) Christenh.
Tectaria adenophora Copel.
Tectaria aenigma C.W.Chen & C.J.Rothf.
Tectaria aequatoriensis (Hieron.) C.Chr.
Tectaria amblyotis (Baker) C.Chr.
Tectaria × amesiana A.A.Eaton = T. coriandrifolia × T. lobata
Tectaria amphiblestra R.M.Tryon & A.F.Tryon
Tectaria andersonii Holttum
Tectaria angelicifolia (Schum.) Copel.
Tectaria angulata (Willd.) Copel.
Tectaria antioquiana (Baker) C.Chr.
Tectaria aspidioides (C.Presl) Copel.
Tectaria athyrioides (Baker) C.Chr.
Tectaria athyriosora M.G.Price
Tectaria atropurpurea A.R.Sm.
Tectaria aurita (Sw.) S.Chandra
Tectaria balansae (C.Chr.) C.Chr.
Tectaria barberi (Hook.) Copel.
Tectaria barteri (J.Sm.) C.Chr.
Tectaria beccariana (Ces.) C.Chr.
Tectaria blumeana (Regel) C.V.Morton
Tectaria borneensis S.Y.Dong
Tectaria brachiata (Zoll. & Moritz) C.V.Morton
Tectaria brevilobata Holttum
Tectaria brooksii Copel.
Tectaria × bulbifera Jermy & T.G.Walker
Tectaria calcarea (J.Sm.) Copel.
Tectaria caluffii Riv.-Giró & C.Sánchez
Tectaria camerooniana (Hook.) Alston
Tectaria ceramensis (Holttum) S.Y.Dong
Tectaria × chaconiana A.Rojas
Tectaria chattagramica (C.B.Clarke) Ching
Tectaria cherasica |
https://en.wikipedia.org/wiki/Didymoglossum%20melanopus | Didymoglossum melanopus is a species of fern in the family Hymenophyllaceae. It is endemic to Ecuador.
The genus Didymoglossum is accepted in the Pteridophyte Phylogeny Group classification of 2016 (PPG I), but not by some other sources. , Plants of the World Online merged the genus into a broadly defined Trichomanes, treating this species as Trichomanes melanopus.
References
Hymenophyllales
Ferns of Ecuador
Endemic flora of Ecuador
Taxonomy articles created by Polbot
Taxobox binomials not recognized by IUCN |
https://en.wikipedia.org/wiki/Rick%20Hodgson | Richard S. Hodgson (born May 23, 1956) is a Canadian former professional ice hockey defenceman. He played 6 games for the Hartford Whalers during the 1979–80 season.
Career statistics
Regular season and playoffs
International
External links
1956 births
Living people
Atlanta Flames draft picks
Calgary Centennials players
Canadian ice hockey defencemen
Hartford Whalers players
Kamloops Rockets players
San Diego Mariners draft picks
Ice hockey people from Medicine Hat
Springfield Indians players
Tulsa Oilers (1964–1984) players |
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