Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of histone acetylation regulation of transcription by RNA polymerase II rhythmic process transcription by RNA polymerase II | CCAAT-binding factor complex; chromatin; nucleoplasm; nucleus; protein-DNA complex; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Homo sapiens | 3D-structure Activator Alternative splicing Biological rhythms DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MEQYTANSNS | MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFS... | positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of histone acetylation regulation of transcription by RNA polymerase II rhythmic process transcription by RNA polymerase II CCAAT-binding factor complex; chro... |
endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport intracellular protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | COPI vesicle coat; COPI-coated vesicle; cytosol; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; Golgi membrane; Golgi-associated vesicle; plasma membrane | structural molecule activity | Rattus norvegicus | Acetylation Cell membrane Cytoplasm Cytoplasmic vesicle Direct protein sequencing Endoplasmic reticulum ER-Golgi transport Golgi apparatus Membrane Microsome Protein transport Reference proteome Repeat Transport | MTAAENVCYT | MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFENLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEHPAHERVLQD... | endoplasmic reticulum to Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport intracellular protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum COPI vesicle coat; COPI-coated vesicle; cytosol; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartm... |
D-glucarate catabolic process galactarate catabolic process glucarate catabolic process | cytoplasm | 2-dehydro-3-deoxyglucarate aldolase activity aldehyde-lyase activity carbon-carbon lyase activity magnesium ion binding | Escherichia coli | 3D-structure Cobalt Direct protein sequencing Iron Lyase Magnesium Manganese Metal-binding Reference proteome | MNNDVFPNKF | MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAELAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK | D-glucarate catabolic process galactarate catabolic process glucarate catabolic process cytoplasm 2-dehydro-3-deoxyglucarate aldolase activity aldehyde-lyase activity carbon-carbon lyase activity magnesium ion binding Escherichia coli 3D-structure Cobalt Direct protein sequencing Iron Lyase Magnesium Manganese Metal-bi... |
one-carbon metabolic process S-adenosylmethionine cycle | cytosol; endoplasmic reticulum; extracellular exosome; melanosome; nucleus | adenosylhomocysteinase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Copper Cytoplasm Direct protein sequencing Disease variant Endoplasmic reticulum Hydrolase Hydroxylation NAD Nucleus One-carbon metabolism Phosphoprotein Reference proteome | MSDKLPYKVA | MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVN... | one-carbon metabolic process S-adenosylmethionine cycle cytosol; endoplasmic reticulum; extracellular exosome; melanosome; nucleus adenosylhomocysteinase activity Homo sapiens 3D-structure Acetylation Alternative splicing Copper Cytoplasm Direct protein sequencing Disease variant Endoplasmic reticulum Hydrolase Hydroxy... |
nucleosome assembly | cytosol; nucleoplasm; nucleosome; nucleus | DNA binding protein heterodimerization activity structural constituent of chromatin | Homo sapiens | 3D-structure Acetylation ADP-ribosylation Chromosome Direct protein sequencing DNA-binding Glycoprotein Hydroxylation Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MPDPAKSAPA | MPDPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK | nucleosome assembly cytosol; nucleoplasm; nucleosome; nucleus DNA binding protein heterodimerization activity structural constituent of chromatin Homo sapiens 3D-structure Acetylation ADP-ribosylation Chromosome Direct protein sequencing DNA-binding Glycoprotein Hydroxylation Isopeptide bond Methylation Nucleosome core... |
actin cytoskeleton organization actin filament depolymerization actin filament fragmentation actin filament severing cytoskeleton organization establishment of spindle localization mitotic cytokinesis negative regulation of apoptotic process positive regulation by host of viral process positive regulation of embryonic ... | actin cytoskeleton; cytoplasm; cytosol; extracellular exosome; extracellular space; focal adhesion; growth cone; lamellipodium; lamellipodium membrane; membrane; nuclear matrix; nucleus; ruffle membrane; vesicle | actin filament binding | Homo sapiens | 3D-structure Acetylation Actin-binding Cell membrane Cell projection Cytoplasm Cytoskeleton Direct protein sequencing Host-virus interaction Isopeptide bond Membrane Nucleus Phosphoprotein Reference proteome Ubl conjugation | MASGVAVSDG | MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL | actin cytoskeleton organization actin filament depolymerization actin filament fragmentation actin filament severing cytoskeleton organization establishment of spindle localization mitotic cytokinesis negative regulation of apoptotic process positive regulation by host of viral process positive regulation of embryonic ... |
cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle assembly intermediate-density lipoprotein particle clearance lipoprotein biosynthetic process melanosome organization negative regulation of amyloid fibril formation positive regulation of amyloid-beta clearance triglyceride-rich lipopro... | chylomicron; extracellular exosome; extracellular matrix; extracellular space; high-density lipoprotein particle; intermediate-density lipoprotein particle; low-density lipoprotein particle; multivesicular body, internal vesicle; very-low-density lipoprotein particle | heparan sulfate proteoglycan binding heparin binding identical protein binding lipid binding low-density lipoprotein particle receptor binding | Cavia porcellus | Chylomicron Endosome Extracellular matrix Glycoprotein HDL Heparin-binding Lipid transport Lipid-binding Oxidation Phosphoprotein Reference proteome Repeat Secreted Signal Transport VLDL | MKVLWAALVV | MKVLWAALVVTLLAGCRADVEPEVEVREPAVWQSGQPWELALSRFWDYLRWVQTLSDQVQEELLSNQVTQELTLLIEDTMKEVKAYKAELEKELGPVAEDTKARLAKELQAAQARLGADMEEVRNRLSQYRSEVQAMLGQSSEELRARLTSHPRKMKRRLQRDIDELQKRMAVYKAGAQEGAERGVSAIRERLGSLIEQGRLQALASQPLQERAQAWGEQMRGRLEKVGSQARDRLEEVREQMEEVRVKVEEQAEAFQARLKSWFEPMMEDMRRQWAELIQKVQVAVGASTSAPSQEP | cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle assembly intermediate-density lipoprotein particle clearance lipoprotein biosynthetic process melanosome organization negative regulation of amyloid fibril formation positive regulation of amyloid-beta clearance triglyceride-rich lipopro... |
2-oxoglutarate metabolic process aspartate biosynthetic process aspartate metabolic process glutamate metabolic process | cytosol; peroxisome | L-aspartate:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding | Saccharomyces cerevisiae | 3D-structure Acetylation Aminotransferase Cytoplasm Direct protein sequencing Peroxisome Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MSATLFNNIE | MSATLFNNIELLPPDALFGIKQRYGQDQRATKVDLGIGAYRDDNGKPWVLPSVKAAEKLIHNDSSYNHEYLGITGLPSLTSNAAKIIFGTQSDAFQEDRVISVQSLSGTGALHISAKFFSKFFPDKLVYLSKPTWANHMAIFENQGLKTATYPYWANETKSLDLNGFLNAIQKAPEGSIFVLHSCAHNPTGLDPTSEQWVQIVDAIASKNHIALFDTAYQGFATGDLDKDAYAVRLGVEKLSTVSPVFVCQSFAKNAGMYGERVGCFHLALTKQAQNKTIKPAVTSQLAKIIRSEVSNPPAYGAKIVAKLLETPELTEQW... | 2-oxoglutarate metabolic process aspartate biosynthetic process aspartate metabolic process glutamate metabolic process cytosol; peroxisome L-aspartate:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding Saccharomyces cerevisiae 3D-structure Acetylation Aminotransferase Cytoplasm Direct protein sequen... |
axon guidance brain-derived neurotrophic factor receptor signaling pathway collateral sprouting memory modulation of chemical synaptic transmission negative regulation of apoptotic signaling pathway negative regulation of myotube differentiation negative regulation of neuron apoptotic process nerve development nerve gr... | axon; cytoplasm; dendrite; endoplasmic reticulum lumen; extracellular region; extracellular space; perinuclear region of cytoplasm; synaptic vesicle | growth factor activity nerve growth factor receptor binding | Homo sapiens | 3D-structure Alternative promoter usage Alternative splicing Cleavage on pair of basic residues Direct protein sequencing Disease variant Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MTILFLTMVI | MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR | axon guidance brain-derived neurotrophic factor receptor signaling pathway collateral sprouting memory modulation of chemical synaptic transmission negative regulation of apoptotic signaling pathway negative regulation of myotube differentiation negative regulation of neuron apoptotic process nerve development nerve gr... |
cell wall integrity MAPK cascade invasive growth in response to glucose limitation osmosensory signaling MAPK cascade osmosensory signaling pathway via Sho1 osmosensor pheromone response MAPK cascade pheromone-dependent signal transduction involved in conjugation with cellular fusion phosphorylation pseudohyphal growth... | cytoplasm | ATP binding identical protein binding MAP kinase kinase kinase activity protein kinase activity protein serine kinase activity SAM domain binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Kinase Nucleotide-binding Pheromone response Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEQTQTAEGT | MEQTQTAEGTDLLIGDEKTNDLPFVQLFLEEIGCTQYLDSFIQCNLVTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQRDKRIEQVNRLKNLMEKVSSLSTATLSMNSELIPEKHCVIFILNDGSAKKVNVNGCFNADSIKKRLIRRLPHELLATNSNGEVTKMVQDYDVFVLDYTKNVLHLLYDVELVTICHANDRVEKNRLIFVSKDQTPSDKAISTSKKLYLRTLSALSQVGPSSSNLLAQNKGISHNNAEGKLRIDNTEKDRIRQIFNQRPPSEFISTNLAGYFPHTDMKRLQKTMRESFRHSARLSIAQRR... | cell wall integrity MAPK cascade invasive growth in response to glucose limitation osmosensory signaling MAPK cascade osmosensory signaling pathway via Sho1 osmosensor pheromone response MAPK cascade pheromone-dependent signal transduction involved in conjugation with cellular fusion phosphorylation pseudohyphal growth... |
bicarbonate transport blood coagulation chloride transmembrane transport chloride transport circadian rhythm erythrocyte development negative regulation of glycolytic process through fructose-6-phosphate negative regulation of urine volume pH elevation plasma membrane phospholipid scrambling positive regulation of T ce... | ankyrin-1 complex; basolateral plasma membrane; cell surface; cortical cytoskeleton; cytoplasmic side of plasma membrane; intercalated disc; membrane; plasma membrane; Z disc | actin binding ankyrin binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride:bicarbonate antiporter activity enzyme binding hemoglobin binding protein homodimerization activity protein-containing complex binding solute:inorganic anion antiporter activity | Rattus norvegicus | Acetylation Alternative splicing Anion exchange Cell membrane Glycoprotein Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MGDMQDHEKV | MGDMQDHEKVLEIPDRDSEEELEHVIEQIAYRDLDIPVTEMQESEALPTEQTATDYIPTSTSTSHPSSSQVYVELQELMMDQRNQELQWVEAAHWIGLEENLREDGVWGRPHLSYLTFWSLLELQKVFSKGTFLLDLAETSLAGVANKLLDSFIYEDQIRPQDRDELLRALLLKRSHAEDLKDLEGVKPAVLTRSGAPSEPLLPHQPSLETKLYCAQAEGGSEEPSPSGILKIPPNSETTLVLVGRASFLVKPVLGFVRLKEAVPLEDLVLPEPVSFLLVLLGPEAPHIDYTQLGRAAATLMTERVFRVTASLAQSRGEL... | bicarbonate transport blood coagulation chloride transmembrane transport chloride transport circadian rhythm erythrocyte development negative regulation of glycolytic process through fructose-6-phosphate negative regulation of urine volume pH elevation plasma membrane phospholipid scrambling positive regulation of T ce... |
extrinsic apoptotic signaling pathway via death domain receptors immune response necroptotic signaling pathway positive regulation of canonical NF-kappaB signal transduction positive regulation of endothelial cell apoptotic process positive regulation of estradiol secretion positive regulation of extrinsic apoptotic si... | cell surface; extracellular space; plasma membrane | cytokine activity tumor necrosis factor receptor binding | Sus scrofa | Cell membrane Cytokine Disulfide bond Glycoprotein Lipoprotein Membrane Myristate Phosphoprotein Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix | MSTESMIRDV | MSTESMIRDVELAEEALAKKAGGPQGSRRCLCLSLFSFLLVAGATTLFCLLHFEVIGPQKEEFPAGPLSINPLAQGLRSSSQTSDKPVAHVVANVKAEGQLQWQSGYANALLANGVKLKDNQLVVPTDGLYLIYSQVLFRGQGCPSTNVFLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKDDRLSAEINLPDYLDFAESGQVYFGIIAL | extrinsic apoptotic signaling pathway via death domain receptors immune response necroptotic signaling pathway positive regulation of canonical NF-kappaB signal transduction positive regulation of endothelial cell apoptotic process positive regulation of estradiol secretion positive regulation of extrinsic apoptotic si... |
cell differentiation cellular response to leukemia inhibitory factor intermediate filament cytoskeleton organization intermediate filament organization nervous system development neurofilament cytoskeleton organization postsynaptic modulation of chemical synaptic transmission tissue regeneration | cytoplasm; cytoplasmic ribonucleoprotein granule; glutamatergic synapse; intermediate filament; neurofilament; postsynapse; postsynaptic density, intracellular component; postsynaptic intermediate filament cytoskeleton; Schaffer collateral - CA1 synapse | protein-containing complex binding structural constituent of postsynaptic intermediate filament cytoskeleton | Rattus norvegicus | Acetylation Coiled coil Developmental protein Differentiation Direct protein sequencing Glycoprotein Intermediate filament Neurogenesis Phosphoprotein Reference proteome | MSFGSEHYLC | MSFGSEHYLCSASSYRKVFGDGSRLSARLSGPGASGSFRSQSLSRSNVASTAACSSASSLGLGLAYRRLPASDGLDLSQAAARTNEYKIIRTNEKEQLQGLNDRFAVFIEKVHQLETQNRALEAELAALRQRHAEPSRVGELFQRELRELRAQLEEASSARAQALLERDGLAEEVQRLRARCEEESRGREGAERALKAQQRDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVAELLATLQASSQAAAEVDVAVAKPDLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNEQAARSTEAIRASREEIHEYRRQLQ... | cell differentiation cellular response to leukemia inhibitory factor intermediate filament cytoskeleton organization intermediate filament organization nervous system development neurofilament cytoskeleton organization postsynaptic modulation of chemical synaptic transmission tissue regeneration cytoplasm; cytoplasmic ... |
chromatin organization DNA repair epigenetic regulation of gene expression negative regulation of SREBP signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination sporulation resulting in formation of a cellular spore transcription elongation-coupled chromatin remodel... | cytosol; HULC complex; nucleus | ATP binding ubiquitin conjugating enzyme activity | Schizosaccharomyces pombe | ATP-binding Chromatin regulator Cytoplasm DNA damage DNA repair Nucleotide-binding Nucleus Reference proteome Sporulation Transcription Transcription regulation Transferase Ubl conjugation pathway | MSTTARRRLM | MSTTARRRLMRDFKRMQQDPPAGVSASPVSDNVMLWNAVIIGPADTPFEDGTFKLVLSFDEQYPNKPPLVKFVSTMFHPNVYANGELCLDILQNRWSPTYDVAAILTSIQSLLNDPNNASPANAEAAQLHRENKKEYVRRVRKTVEDSWES | chromatin organization DNA repair epigenetic regulation of gene expression negative regulation of SREBP signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination sporulation resulting in formation of a cellular spore transcription elongation-coupled chromatin remodel... |
asymmetric neuroblast division embryonic development via the syncytial blastoderm follicle cell of egg chamber development G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle germarium-derived cystoblast division male meiotic nuclear division mitotic G2 DNA damage checkpoint signaling mitotic G2... | fusome; nucleus | ATP binding cyclin-dependent protein serine/threonine kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Drosophila melanogaster | ATP-binding Cell cycle Cell division Kinase Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MEDFEKIEKI | MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKHENIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCHRRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPRYSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGLVRN | asymmetric neuroblast division embryonic development via the syncytial blastoderm follicle cell of egg chamber development G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle germarium-derived cystoblast division male meiotic nuclear division mitotic G2 DNA damage checkpoint signaling mitotic G2... |
cell division G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle positive regulation of receptor signaling pathway via JAK-STAT protein phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression response to organic substance signal transduction | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus | ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity | Drosophila melanogaster | ATP-binding Cell cycle Cell division Kinase Mitosis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MTTILDNFQR | MTTILDNFQRAEKIGEGTYGIVYKARSNSTGQDVALKKIRLEGETEGVPSTAIREISLLKNLKHPNVVQLFDVVISGNNLYMIFEYLNMDLKKLMDKKKDVFTPQLIKSYMHQILDAVGFCHTNRILHRDLKPQNLLVDTAGKIKLADFGLARAFNVPMRAYTHEVVTLWYRAPEILLGTKFYSTGVDIWSLGCIFSEMIMRRSLFPGDSEIDQLYRIFRTLSTPDETNWPGVTQLPDFKTKFPRWEGTNMPQPITEHEAHELIMSMLCYDPNLRISAKDALQHAYFRNVQHVDHVALPVDPNAGSASRLTRLV | cell division G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle positive regulation of receptor signaling pathway via JAK-STAT protein phosphorylation regulation of G2/M transition of mitotic cell cycle regulation of gene expression response to organic substance signal transduction cyclin-depe... |
chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential synaptic transmission, GABAergic | chloride channel complex; dendrite membrane; GABA-A receptor complex; neuron projection; postsynapse; postsynaptic membrane; receptor complex; synapse | GABA receptor binding GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity | Rattus norvegicus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Lipoprotein Membrane Palmitate Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MGSGKVFLFS | MGSGKVFLFSPSLLWSQTRGVRLIFLLLTLHLGNCIDKADDEDDEDLTMNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTLRLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEISHTISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIA... | chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway regulation of postsynaptic membrane potential synaptic transmission, GABAergic chloride channel complex; dendrite membrane; GABA-A receptor complex; neuron projection; postsynapse; postsynaptic membrane; receptor c... |
chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly regulation of postsynaptic membrane potential synaptic transmission, GABAergic | axon; chloride channel complex; dendrite; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; inhibitory synapse; neuron projection; neuronal cell body; postsynapse; postsynaptic specialization membrane; presynaptic active zone membrane; synapse; synaptic vesicle membrane | benzodiazepine receptor activity GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential transmitter-gated monoatomic ion channel activity... | Rattus norvegicus | Cell membrane Cell projection Chloride Chloride channel Cytoplasmic vesicle Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MRTKLSTCNV | MRTKLSTCNVWFPLLVLLVWNPARLVLANIQEDEAKNNITIFTRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNSMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNPSDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVC... | chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly regulation of postsynaptic membrane potential synaptic transmission, GABAergic axon; chloride channel complex; dendrite; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; inhibitory synapse; neuron proje... |
acrosome matrix dispersal acrosome reaction activation of adenylate cyclase activity binding of sperm to zona pellucida penetration of zona pellucida protein catabolic process response to steroid hormone single fertilization | acrosomal matrix; acrosomal vesicle; Golgi-associated vesicle; protein-containing complex | amidase activity fucose binding mannose binding peptidase activity serine-type endopeptidase activity serine-type peptidase activity | Mus musculus | Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MVEMLPTVAV | MVEMLPTVAVLVLAVSVVAKDNTTCDGPCGLRFRQNSQAGTRIVSGQSAQLGAWPWMVSLQIFTSHNSRRYHACGGSLLNSHWVLTAAHCFDNKKKVYDWRLVFGAQEIEYGRNKPVKEPQQERYVQKIVIHEKYNVVTEGNDIALLKITPPVTCGNFIGPCCLPHFKAGPPQIPHTCYVTGWGYIKEKAPRPSPVLMEARVDLIDLDLCNSTQWYNGRVTSTNVCAGYPEGKIDTCQGDSGGPLMCRDNVDSPFVVVGITSWGVGCARAKRPGVYTATWDYLDWIASKIGPNALHLIQPATPHPPTTRHPMVSFHPPSL... | acrosome matrix dispersal acrosome reaction activation of adenylate cyclase activity binding of sperm to zona pellucida penetration of zona pellucida protein catabolic process response to steroid hormone single fertilization acrosomal matrix; acrosomal vesicle; Golgi-associated vesicle; protein-containing complex amida... |
chromatin remodeling chromosome organization DNA damage response G1/S transition of mitotic cell cycle intracellular iron ion homeostasis MAPK cascade negative regulation of apoptotic process negative regulation of cell division negative regulation of monocyte differentiation negative regulation of stress-activated MAP... | nucleolus; nucleoplasm; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding protein dimerization activity protein-containing complex binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Pan troglodytes | Acetylation Activator Alternative initiation DNA-binding Glycoprotein Isopeptide bond Nucleus Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation Ubl conjugation | MDFFRIVENQ | MDFFRIVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCPSQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTH... | chromatin remodeling chromosome organization DNA damage response G1/S transition of mitotic cell cycle intracellular iron ion homeostasis MAPK cascade negative regulation of apoptotic process negative regulation of cell division negative regulation of monocyte differentiation negative regulation of stress-activated MAP... |
carbohydrate transport glucose transmembrane transport | cell periphery; fungal-type vacuole; plasma membrane | carbohydrate:proton symporter activity fructose transmembrane transporter activity glucose transmembrane transporter activity mannose transmembrane transporter activity pentose transmembrane transporter activity | Saccharomyces cerevisiae | Acetylation Glycoprotein Membrane Phosphoprotein Reference proteome Repeat Sugar transport Transmembrane Transmembrane helix Transport | MSEFATSRVE | MSEFATSRVESGSQQTSIHSTPIVQKLETDESPIQTKSEYTNAELPAKPIAAYWTVICLCLMIAFGGFVFGWDTGTISGFVNQTDFKRRFGQMKSDGTYYLSDVRTGLIVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIVIQIASSDKWYQYFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMITLGIFLGYCTNYGTKDYSNSVQWRVPLGLNFAFAIFMIAGMLMVPESPRFLVEKGRYEDAKRSLAKSNKVTIEDPSIVAEMDTIMANVETERLAGNASWGELFSNKGAILPRVIMGI... | carbohydrate transport glucose transmembrane transport cell periphery; fungal-type vacuole; plasma membrane carbohydrate:proton symporter activity fructose transmembrane transporter activity glucose transmembrane transporter activity mannose transmembrane transporter activity pentose transmembrane transporter activity ... |
regulation of translational initiation | cytosol; eukaryotic translation initiation factor 4F complex | RNA binding translation initiation factor activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Direct protein sequencing Initiation factor Isopeptide bond Phosphoprotein Protein biosynthesis Reference proteome RNA-binding Ubl conjugation | MAASAKKKNK | MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSWADETDDLEGDVSTTWHSNDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDD... | regulation of translational initiation cytosol; eukaryotic translation initiation factor 4F complex RNA binding translation initiation factor activity Homo sapiens 3D-structure Acetylation Alternative splicing Direct protein sequencing Initiation factor Isopeptide bond Phosphoprotein Protein biosynthesis Reference prot... |
gluconeogenesis one-carbon metabolic process | cytoplasm; mitochondrion | carbonate dehydratase activity zinc ion binding | Mus musculus | 3D-structure Direct protein sequencing Lyase Metal-binding Mitochondrion Reference proteome Transit peptide Zinc | MLRRDPRKPL | MLRRDPRKPLAILRHVGLLCATGPQRWRFQHSCAEEHSNCARHPLWTGPVSSAEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGYFFQVEFDDSCEDSGISGGPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLAVIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGPFDPSCLLPACRDYWTYPGSLTTPPLAESVTWIVQKTPVEVSPSQLSTFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFRLDRTKMRS | gluconeogenesis one-carbon metabolic process cytoplasm; mitochondrion carbonate dehydratase activity zinc ion binding Mus musculus 3D-structure Direct protein sequencing Lyase Metal-binding Mitochondrion Reference proteome Transit peptide Zinc MLRRDPRKPL MLRRDPRKPLAILRHVGLLCATGPQRWRFQHSCAEEHSNCARHPLWTGPVSSAEGTRQSPINIQW... |
brain development glucose metabolic process lipid metabolic process lipid transport negative regulation of cytokine production involved in inflammatory response negative regulation of focal adhesion assembly negative regulation of lipoprotein lipid oxidation negative regulation of monocyte chemotactic protein-1 product... | cytoplasm; cytosolic ribosome; dendrite; extracellular space; neuronal cell body; perinuclear region of cytoplasm | cholesterol binding | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Lipid-binding Pyrrolidone carboxylic acid Reference proteome Secreted Signal Transport | MATMLLLLAT | MATMLLLLATLAGLFTTTEGQSFHLGKCPSPPVQENFDVKKYLGRWYEIEKIPVSFEKGNCIQANYSLMENGNIKVLNKELRPDGTLNQVEGEAKQSNMSEPAKLEVQFFSLMPPAPYWILATDYESYALVYSCTTFFWFFHVDYVWILGRNPYLPPETITYLKYILTSNDIDIAKITTKDQANCPDFL | brain development glucose metabolic process lipid metabolic process lipid transport negative regulation of cytokine production involved in inflammatory response negative regulation of focal adhesion assembly negative regulation of lipoprotein lipid oxidation negative regulation of monocyte chemotactic protein-1 product... |
G1/S transition of mitotic cell cycle mitotic cell cycle positive regulation of autophagosome assembly regulation of translation TOR signaling | cytoplasm; cytoplasmic stress granule; cytosol; nucleus; protein phosphatase type 2A complex | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Saccharomyces cerevisiae | Hydrolase Manganese Metal-binding Methylation Protein phosphatase Reference proteome | MDTDLDVPMQ | MDTDLDVPMQDAVTEQLTPTVSEDMDLNNNSSDNNAEEFSVDDLKPGSSGIADHKSSKPLELNNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPITALVDNKIFCLHGGLSPMIETIDQVRELNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDVSEQFNHTNDLSLIARAHQLVMEGYAWSHQQNVVTIF... | G1/S transition of mitotic cell cycle mitotic cell cycle positive regulation of autophagosome assembly regulation of translation TOR signaling cytoplasm; cytoplasmic stress granule; cytosol; nucleus; protein phosphatase type 2A complex metal ion binding myosin phosphatase activity protein serine/threonine phosphatase a... |
G1/S transition of mitotic cell cycle mitotic cell cycle negative regulation of ribonucleoprotein complex localization positive regulation of autophagosome assembly regulation of translation TOR signaling | condensed chromosome, centromeric region; cytosol; nuclear periphery; nucleus; protein phosphatase type 2A complex | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Saccharomyces cerevisiae | Hydrolase Manganese Metal-binding Methylation Phosphoprotein Protein phosphatase Reference proteome | MDMEIDDPMH | MDMEIDDPMHGSDEDQLSPTLDEDMNSDDGKNNTKARSNDEDTDEELEDFNFKPGSSGIADHKSSKPLKLTNTNINQLDQWIEHLSKCEPLSEDDVARLCKMAVDVLQFEENVKPINVPVTICGDVHGQFHDLLELFKIGGPCPDTNYLFMGDYVDRGYYSVETVSYLVAMKVRYPHRITILRGNHESRQITQVYGFYDECLRKYGSANVWKMFTDLFDYFPVTALVDNKIFCLHGGLSPMIETIDQVRDLNRIQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGFTFGQDISEQFNHTNDLSLIARAHQLVMEGYSWSH... | G1/S transition of mitotic cell cycle mitotic cell cycle negative regulation of ribonucleoprotein complex localization positive regulation of autophagosome assembly regulation of translation TOR signaling condensed chromosome, centromeric region; cytosol; nuclear periphery; nucleus; protein phosphatase type 2A complex ... |
autophagy cellular response to lipopolysaccharide cellular response to type II interferon defense response to bacterium defense response to protozoan dendritic cell differentiation follicular B cell differentiation germinal center B cell differentiation immune response immune system process myeloid cell differentiation... | cytoplasm; nucleoplasm; nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region seq... | Mus musculus | Activator Autophagy Cytoplasm DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MCDRNGGRRL | MCDRNGGRRLRQWLIEQIDSSMYPGLIWENDEKTMFRIPWKHAGKQDYNQEVDASIFKAWAVFKGKFKEGDKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISEPYKVYRIVPEEEQKCKLGVAPAGCMSEVPEMECGRSEIEELIKEPSVDEYMGMTKRSPSPPEACRSQILPDWWVQQPSAGLPLVTGYAAYDTHHSAFSQMVISFYYGGKLVGQATTTCLEGCRLSLSQPGLPKLYGPDGLEPVCFPTADTIPSERQRQVTRKLFGHLERGVLLHSNRKGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVF... | autophagy cellular response to lipopolysaccharide cellular response to type II interferon defense response to bacterium defense response to protozoan dendritic cell differentiation follicular B cell differentiation germinal center B cell differentiation immune response immune system process myeloid cell differentiation... |
carbohydrate metabolic process cell adhesion fusion of sperm to egg plasma membrane involved in single fertilization | plasma membrane; side of membrane | hyalurononglucosaminidase activity | Cavia porcellus | Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Glycosidase GPI-anchor Hydrolase Lipoprotein Membrane Reference proteome Signal | MGAFTFKHSF | MGAFTFKHSFFGSFVECSGVLQTVFIFLLIPCCLADKRAPPLIPNVPLLWVWNAPTEFCIGGTNQPLDMSFFSIVGTPRKNITGQSITLYYVDRLGYYPYIDPHTGAIVHGGLPQLMNLQQHLRKSRQDILFYMPTDSVGLAVIDWEEWRPTWTRNWRPKDIYRNKSIELVKSQHPQYNHSYAVAVAKRDFERTGKAFMLETLKLGKSLRPSSLWGYYLFPDCYNTHFTKPNYDGHCPPIELQRNNDLQWLWNDSTALYPSVYLTSRVRSSQNGALYVRNRVHESIRVSKLMDDKNPLPIYVYIRLVFTDQTTTFLELDD... | carbohydrate metabolic process cell adhesion fusion of sperm to egg plasma membrane involved in single fertilization plasma membrane; side of membrane hyalurononglucosaminidase activity Cavia porcellus Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Glycosidase GPI-anchor Hydrolase Lip... |
negative regulation of DNA-templated transcription podocyte differentiation | cell junction; chromatin; COP9 signalosome; cortical cytoskeleton; cytoplasm; growth cone; nuclear matrix; nuclear speck; nucleus; plasma membrane; PML body | protein domain specific binding transcription cis-regulatory region binding transcription corepressor activity | Gallus gallus | Cytoplasm Cytoskeleton Developmental protein Lipoprotein Myristate Phosphoprotein Reference proteome | MGGKLSKKKK | MGGKLSKKKKGYSVNDEKAKDKDKKAEGAATEEEETPKEAEDAQQTTETTEVKENNKEEKVEKDAQVSANKTEEKEGEKEKTVTQEEAQKAEPEKSEAVVDAKVEPQKNNEQAPKQEEPAAASAPAASSEAPKTSEPSSDAKASQPSEATAPSKADDKSKEEGEAKKTEAPATPAAQETKSEVAPASDSKPSSSEAAPSSKETVAATAAPSSTAKASDPSAPPEEAKPSEAPATNSDQTIAVQD | negative regulation of DNA-templated transcription podocyte differentiation cell junction; chromatin; COP9 signalosome; cortical cytoskeleton; cytoplasm; growth cone; nuclear matrix; nuclear speck; nucleus; plasma membrane; PML body protein domain specific binding transcription cis-regulatory region binding transcripti... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway axon midline choice point recognition cellular response to carbon dioxide flight behavior metarhodopsin inactivation mucosal immune response negative regulation of compound eye retinal cell programmed cell death neuron cellular homeostasis photot... | axon; heterotrimeric G-protein complex; inaD signaling complex; plasma membrane; rhabdomere | G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding phospholipase activator activity | Drosophila melanogaster | Alternative splicing Cell projection GTP-binding Lipoprotein Magnesium Metal-binding Nucleotide-binding Palmitate Reference proteome Sensory transduction Transducer Vision | MECCLSEEAK | MECCLSEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHSELADLVMSIDYETVTTFEDPYLNAIKTLWDDAGIQECYDRRREYQLTDSAKYYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPKQDHAAAKQFVLKKYLACNPDPERQCYS... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway axon midline choice point recognition cellular response to carbon dioxide flight behavior metarhodopsin inactivation mucosal immune response negative regulation of compound eye retinal cell programmed cell death neuron cellular homeostasis photot... |
cell division meiotic centromeric cohesion protection in anaphase I mitotic cell cycle negative regulation of G2/M transition of mitotic cell cycle negative regulation of induction of conjugation with cellular fusion signaling | chromosome, centromeric region; cytoplasm; cytosol; nucleus; protein phosphatase type 2A complex | metal ion binding myosin phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity | Schizosaccharomyces pombe | Cell cycle Cell division Hydrolase Manganese Metal-binding Methylation Mitosis Protein phosphatase Reference proteome | MSIDPANDSK | MSIDPANDSKLAPEANDATLGDVDRWIEQLKKCEPLSEADVEMLCDKAREVLCQENNVQPVRNPVTVCGDIHGQFHDLMELFKIGGDVPDMNYLFMGDYVDRGYHSVETVSLLVAMKLRYPNRITILRGNHESRQITQVYGFYDECLRKYGSANVWKHFTNLFDYFPLTALIEDRIFCLHGGLSPSIDSLDHVRTLDRVQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDISETFNHANGLSLTARAHQLVMEGFNWAHDGDVVTIFSAPNYCYRCGNQAAILEVDDTMNQVFLQFDPAPREGEPVIARRTPDY... | cell division meiotic centromeric cohesion protection in anaphase I mitotic cell cycle negative regulation of G2/M transition of mitotic cell cycle negative regulation of induction of conjugation with cellular fusion signaling chromosome, centromeric region; cytoplasm; cytosol; nucleus; protein phosphatase type 2A comp... |
antigen processing and presentation blood coagulation complement-dependent cytotoxicity cytotoxic T cell degranulation exocytosis exosomal secretion melanocyte differentiation melanosome localization melanosome transport multivesicular body organization multivesicular body sorting pathway natural killer cell degranulat... | apical plasma membrane; dendrite; exocytic vesicle; Golgi apparatus; late endosome; lysosome; melanosome; multivesicular body membrane; photoreceptor outer segment; secretory granule; Weibel-Palade body | G protein activity GDP binding GTP binding GTPase activity myosin V binding protein domain specific binding | Rattus norvegicus | Acetylation Disulfide bond Endosome Exocytosis GTP-binding Hydrolase Lipoprotein Lysosome Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Reference proteome | MSDGDYDYLI | MSDGDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRANGPDGTVGRGQRIHLQLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKSDLEDQRAVKEEEARELAEKYGIPYFETSAANGTNISQAIEMLLDLIMKRMERCVDKSWIPEGVVRSNGHTSTDQLSEEKEKGLCGC | antigen processing and presentation blood coagulation complement-dependent cytotoxicity cytotoxic T cell degranulation exocytosis exosomal secretion melanocyte differentiation melanosome localization melanosome transport multivesicular body organization multivesicular body sorting pathway natural killer cell degranulat... |
cell wall mannoprotein biosynthetic process mannosylation protein N-linked glycosylation sporulation resulting in formation of a cellular spore | endoplasmic reticulum membrane; mannan polymerase complex | alpha-1,6-mannosyltransferase activity | Saccharomyces cerevisiae | Endoplasmic reticulum Glycoprotein Golgi apparatus Growth regulation Membrane Phosphoprotein Reference proteome Signal-anchor Sporulation Transmembrane Transmembrane helix | MGMFFNLRSN | MGMFFNLRSNIKKKAMDNGLSLPISRNGSSNNIKDKRSEHNSNSLKGKYRYQPRSTPSKFQLTVSITSLIIIAVLSLYLFISFLSGMGIGVSTQNGRSLLGSSKSSENYKTIDLEDEEYYDYDFEDIDPEVISKFDDGVQHYLISQFGSEVLTPKDDEKYQRELNMLFDSTVEEYDLSNFEGAPNGLETRDHILLCIPLRNAADVLPLMFKHLMNLTYPHELIDLAFLVSDCSEGDTTLDALIAYSRHLQNGTLSQIFQEIDAVIDSQTKGTDKLYLKYMDEGYINRVHQAFSPPFHENYDKPFRSVQIFQKDFGQVIGQ... | cell wall mannoprotein biosynthetic process mannosylation protein N-linked glycosylation sporulation resulting in formation of a cellular spore endoplasmic reticulum membrane; mannan polymerase complex alpha-1,6-mannosyltransferase activity Saccharomyces cerevisiae Endoplasmic reticulum Glycoprotein Golgi apparatus Gr... |
monoatomic ion transport protein import into mitochondrial matrix protein insertion into mitochondrial outer membrane | cytosol; mitochondrial intermembrane space; mitochondrial outer membrane; mitochondrial outer membrane translocase complex; mitochondrion; pore complex | porin activity protein transmembrane transporter activity | Saccharomyces cerevisiae | 3D-structure Ion transport Membrane Mitochondrion Mitochondrion outer membrane Porin Protein transport Reference proteome Transmembrane Transmembrane beta strand Transport | MSAPTPLAEA | MSAPTPLAEASQIPTIPALSPLTAKQSKGNFFSSNPISSFVVDTYKQLHSHRQSLELVNPGTVENLNKEVSRDVFLSQYFFTGLRADLNKAFSMNPAFQTSHTFSIGSQALPKYAFSALFANDNLFAQGNIDNDLSVSGRLNYGWDKKNISKVNLQISDGQPTMCQLEQDYQASDFSVNVKTLNPSFSEKGEFTGVAVASFLQSVTPQLALGLETLYSRTDGSAPGDAGVSYLTRYVSKKQDWIFSGQLQANGALIASLWRKVAQNVEAGIETTLQAGMVPITDPLMGTPIGIQPTVEGSTTIGAKYEYRQSVYRGTLDS... | monoatomic ion transport protein import into mitochondrial matrix protein insertion into mitochondrial outer membrane cytosol; mitochondrial intermembrane space; mitochondrial outer membrane; mitochondrial outer membrane translocase complex; mitochondrion; pore complex porin activity protein transmembrane transporter a... |
cell differentiation cell-cell adhesion mesoderm development nervous system development transmembrane transport | membrane; plasma membrane | channel activity monoatomic cation channel activity | Drosophila melanogaster | Developmental protein Differentiation Ion channel Ion transport Membrane Neurogenesis Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MADESLHTVP | MADESLHTVPLEHNIDYHIVTLFERLEAMRKDSHGGGHGVNNRLSSTLQAPKRSMQAEIRTLEFWRSIISECLASFMYVFIVCGAAAGVGVGASVSSVLLATALASGLAMATLTQCFLHISGAHINPAVTLALCVVRSISPIRAAMYITAQCGGGIAGAALLYGVTVPGYQGNLQAAISHSAALAAWERFGVEFILTFLVVLCYFVSTDPMKKFMGNSAASIGCAYSACCFVSMPYLNPARSLGPSFVLNKWDSHWVYWFGPLVGGMASGLVYEYIFNSRNRNLRHNKGSIDNDSSSIHSEDELNYDMDMEKPNKYQQSQ... | cell differentiation cell-cell adhesion mesoderm development nervous system development transmembrane transport membrane; plasma membrane channel activity monoatomic cation channel activity Drosophila melanogaster Developmental protein Differentiation Ion channel Ion transport Membrane Neurogenesis Phosphoprotein Refer... |
germarium-derived egg chamber formation intraciliary transport negative regulation of BMP signaling pathway negative regulation of smoothened signaling pathway positive regulation of nucleocytoplasmic transport positive regulation of protein ubiquitination protein autophosphorylation segment polarity determination smoo... | cilium; cytoplasm; cytosol; Hedgehog signaling complex; protein-containing complex | ATP binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity smoothened binding | Drosophila melanogaster | 3D-structure ATP-binding Developmental protein Kinase Nucleotide-binding Phosphoprotein Reference proteome Segmentation polarity protein Serine/threonine-protein kinase Transferase | MNRYAVSSLV | MNRYAVSSLVGQGSFGCVYKATRKDDSKVVAIKVISKRGRATKELKNLRRECDIQARLKHPHVIEMIESFESKTDLFVVTEFALMDLHRYLSYNGAMGEEPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGLARNMTLGTHVLTSIKGTPLYMAPELLAEQPYDHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHEDVKWPSTLTSECRSFLQGLLEKDPGLRISWTQLLCHPFVEGRIFIAETQAEAAKESPFTNPEAKVKSSKQSDPEVGDLDEALAALDFGESRQENLTTSRDSINAI... | germarium-derived egg chamber formation intraciliary transport negative regulation of BMP signaling pathway negative regulation of smoothened signaling pathway positive regulation of nucleocytoplasmic transport positive regulation of protein ubiquitination protein autophosphorylation segment polarity determination smoo... |
axon guidance axonal fasciculation axonogenesis central nervous system development heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | axon; basolateral plasma membrane; cytoplasm; plasma membrane | cell adhesion receptor activity | Drosophila melanogaster | Cell adhesion Disulfide bond Glycoprotein Membrane Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane helix | MGELEEKETP | MGELEEKETPPTETTAAQQEALEEPKETDKMLDKKEDAKEKTPSPQTSKPASPNAGKKSSPVAEKKIDDAELAKSKSGNGEEIIDIPAENGTKPDSADDKKISKEEREVKPKKIPIGGLKLPGFFMKNKPKADGDGAEGELLEKEKEEDKDKEANGDAATGSGKDEQKSRPGLGERLRSFFARKPSAEKEKKQLVNGDADAKSEATAEATPAEDASDAPPKRGLLNAIKLPIANMIPKKKSNDDVELGLGKAGLASMETLDDSLKDQDTVDRAPVKTNGTEELKGELKDEKLAAEEKLAAEEEEQNRPVSLLTRLRGYKC... | axon guidance axonal fasciculation axonogenesis central nervous system development heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules axon; basolateral plasma membrane; cytoplasm; plasma membrane cell adhesion receptor activity Drosophila melanogaster Cell adhesion Disulfide bond Glycoprotein M... |
actin cytoskeleton organization cellular response to calcium ion dendritic spine maintenance inositol metabolic process inositol phosphate biosynthetic process modification of postsynaptic actin cytoskeleton phosphatidylinositol phosphate biosynthetic process phosphorylation positive regulation of dendritic spine morph... | cytoplasm; cytoskeleton; cytosol; dendritic spine; glutamatergic synapse; nucleus; postsynaptic actin cytoskeleton | ATP binding calmodulin binding calmodulin-dependent protein kinase activity inositol tetrakisphosphate kinase activity inositol-1,4,5-trisphosphate 3-kinase activity small GTPase binding | Homo sapiens | 3D-structure ATP-binding Calmodulin-binding Cytoplasm Cytoskeleton Kinase Methylation Nucleotide-binding Phosphoprotein Reference proteome Transferase | MTLPGGPTGM | MTLPGGPTGMARPGGARPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAPPAPVIPQLTVTAEEPDVPPTSPGPPERERDCLPAAGSSHLQQPRRLSTSSVSSTGSSSLLEDSEDDLLSDSESRSRGNVQLEAGEDVGQKNHWQKIRTMVNLPVISPFKKRYAWVQLAGHTGSFKAAGTSGLILKRCSEPERYCLARLMADALRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWRE... | actin cytoskeleton organization cellular response to calcium ion dendritic spine maintenance inositol metabolic process inositol phosphate biosynthetic process modification of postsynaptic actin cytoskeleton phosphatidylinositol phosphate biosynthetic process phosphorylation positive regulation of dendritic spine morph... |
innate immune response negative regulation of glycoprotein metabolic process negative regulation of monocyte differentiation negative regulation of viral entry into host cell negative regulation of viral process protein-containing complex assembly | extracellular space; protein-containing complex | calcium ion binding carbohydrate binding complement component C1q complex binding identical protein binding virion binding | Rattus norvegicus | Amyloid Calcium Disulfide bond Glycoprotein Lectin Metal-binding Reference proteome Secreted Signal | MDKLLLWMSV | MDKLLLWMSVFTSLLSEAFAQTDLNQKVFVFPRESETDYVKLIPWLEKPLQNFTLCFRAYSDLSRSQSLFSYSVNSRDNELLIYKDKVGQYSLYIGNSKVTVRGLEEFPSPIHFCTSWESSSGIAEFWVNGKPWVKKGLQKGYTVKSSPSIVLGQEQDTYGGGFDKTQSFVGEIADLYMWDSVLTPENIHSVDRGFPPNPNILDWRALNYEINGYVVIKPRMWDNKSS | innate immune response negative regulation of glycoprotein metabolic process negative regulation of monocyte differentiation negative regulation of viral entry into host cell negative regulation of viral process protein-containing complex assembly extracellular space; protein-containing complex calcium ion binding carb... |
embryo development ending in birth or egg hatching interneuron migration positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II spinal cord interneuron axon guidance | axon; neuronal cell body; nucleoplasm; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Reference proteome | MESRKDMVMF | MESRKDMVMFLDGGQLGTLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLSPRAGPPTSRERGGGGQEEEPVDGLAGSAAGLGAEPRSAGAAMLGPGPPVPSADSLSGQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKAPGSDALGSSPTSGSEAPKSNGGSGGSGSQGTLACSASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGPLRPLDTFRVLSQPYPRP... | embryo development ending in birth or egg hatching interneuron migration positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II spinal cord interneuron axon guidance axon; neuronal cell body; nucleoplasm; nucleus DNA-binding transcription factor activity, RNA polymera... |
calcium ion import calcium ion import across plasma membrane calcium ion transmembrane transport cell communication intracellular sodium ion homeostasis positive regulation of bone mineralization positive regulation of the force of heart contraction response to muscle stretch sodium ion import across plasma membrane so... | axon; nucleoplasm; plasma membrane; postsynapse; sarcolemma | ankyrin binding calcium ion binding calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration calcium:sodium antiporter activity calmodulin binding | Canis lupus familiaris | 3D-structure Antiport Calcium Calcium transport Calmodulin-binding Cell membrane Glycoprotein Ion transport Membrane Metal-binding Phosphoprotein Reference proteome Repeat Signal Sodium Sodium transport Transmembrane Transmembrane helix Transport | MLQLRLLPTF | MLQLRLLPTFSMGCHLLAVVALLFSHVDLISAETEMEGEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEAR... | calcium ion import calcium ion import across plasma membrane calcium ion transmembrane transport cell communication intracellular sodium ion homeostasis positive regulation of bone mineralization positive regulation of the force of heart contraction response to muscle stretch sodium ion import across plasma membrane so... |
ethylene biosynthetic process one-carbon metabolic process S-adenosylmethionine biosynthetic process | cytosol; extracellular region; plant-type cell wall | ATP binding metal ion binding methionine adenosyltransferase activity | Arabidopsis thaliana | 3D-structure ATP-binding Cobalt Cytoplasm Magnesium Metal-binding Nucleotide-binding One-carbon metabolism Potassium Reference proteome S-nitrosylation Transferase | METFLFTSES | METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRAIGFVSDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKCPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYYNDKGAMVPIRVHTVLISTQHDETVTNDEIARDLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARRALVQVSYAIGVPEPLSVFV... | ethylene biosynthetic process one-carbon metabolic process S-adenosylmethionine biosynthetic process cytosol; extracellular region; plant-type cell wall ATP binding metal ion binding methionine adenosyltransferase activity Arabidopsis thaliana 3D-structure ATP-binding Cobalt Cytoplasm Magnesium Metal-binding Nucleotide... |
cardiac muscle contraction heart contraction heart development intracellular calcium ion homeostasis regulation of cardiac muscle contraction by calcium ion signaling regulation of muscle contraction regulation of smooth muscle contraction regulation of systemic arterial blood pressure by ischemic conditions skeletal m... | cardiac myofibril; cardiac Troponin complex; contractile fiber; cytoplasm; myofibril; sarcomere; troponin complex | actin binding actin filament binding calcium channel inhibitor activity calcium-dependent protein binding protein domain specific binding protein kinase binding troponin C binding troponin T binding | Rattus norvegicus | Acetylation Actin-binding Muscle protein Phosphoprotein Reference proteome | MADESSDAAG | MADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKSKISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLSTRCQPLVLDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLDLRAHLKQVKKEDIEKENREVGDWRKNIDALSGMEGRKKKFEG | cardiac muscle contraction heart contraction heart development intracellular calcium ion homeostasis regulation of cardiac muscle contraction by calcium ion signaling regulation of muscle contraction regulation of smooth muscle contraction regulation of systemic arterial blood pressure by ischemic conditions skeletal m... |
killing by symbiont of host cells proteolysis | extracellular matrix; extracellular region; extracellular space | calcium ion binding metalloendopeptidase activity toxin activity zinc ion binding | Serratia marcescens | 3D-structure Calcium Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Repeat Secreted Toxin Virulence Zinc Zymogen | MQSTKKAIEI | MQSTKKAIEITESSLAAATTGYDAVDDLLHYHERGNGIQINGKDSFSNEQAGLFITRENQTWNGYKVFGQPVKLTFSFPDYKFSSTNVAGDTGLSKFSAEQQQQAKLSLQSWADVANITFTEVAAGQKANITFGNYSQDRPGHYDYGTQAYAFLPNTIWQGQDLGGQTWYNVNQSNVKHPATEDYGRQTFTHEIGHALGLSHPGDYNAGEGNPTYNDVTYAEDTRQFSLMSYWSETNTGGDNGGHYAAAPLLDDIAAIQHLYGANPSTRTGDTVYGFNSNTGRDFLSTTSNSQKVIFAAWDAGGNDTFDFSGYTANQRIN... | killing by symbiont of host cells proteolysis extracellular matrix; extracellular region; extracellular space calcium ion binding metalloendopeptidase activity toxin activity zinc ion binding Serratia marcescens3D-structure Calcium Direct protein sequencing Hydrolase Metal-binding Metalloprotease Protease Repeat Secret... |
embryonic placenta development embryonic placenta morphogenesis glucose metabolic process in utero embryonic development negative regulation of muscle cell differentiation negative regulation of transcription by RNA polymerase II ossification positive regulation of activated T cell proliferation positive regulation of ... | extracellular space | growth factor activity hormone activity insulin-like growth factor receptor binding integrin binding protein serine/threonine kinase activator activity | Sus scrofa | Carbohydrate metabolism Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glucose metabolism Glycoprotein Growth factor Hormone Mitogen Osteogenesis Reference proteome Secreted Signal | MGIPMRKPLL | MGIPMRKPLLVLLVFLALASCCYAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVNRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFRYDTWKQSAQRLRRGLPALLRARRGRTLAKELEAVREAKRHRPLTARPTRDPAAHGGASPEASGHRK | embryonic placenta development embryonic placenta morphogenesis glucose metabolic process in utero embryonic development negative regulation of muscle cell differentiation negative regulation of transcription by RNA polymerase II ossification positive regulation of activated T cell proliferation positive regulation of ... |
asymmetric neuroblast division autophagy centriole replication centrosome cycle chromosome segregation establishment of epithelial cell polarity microtubule cytoskeleton organization mitotic cell cycle negative regulation of hippo signaling negative regulation of insulin receptor signaling pathway negative regulation o... | cytoplasm; cytosol; FAR/SIN/STRIPAK complex; nucleoplasm; protein phosphatase type 2A complex | metal ion binding myosin phosphatase activity phosphatase regulator activity protein serine/threonine phosphatase activity | Drosophila melanogaster | Hydrolase Manganese Metal-binding Methylation Protein phosphatase Reference proteome | MEDKATTKDL | MEDKATTKDLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPRRGEPHVTRRTPDYFL | asymmetric neuroblast division autophagy centriole replication centrosome cycle chromosome segregation establishment of epithelial cell polarity microtubule cytoskeleton organization mitotic cell cycle negative regulation of hippo signaling negative regulation of insulin receptor signaling pathway negative regulation o... |
positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of histone acetylation regulation of transcription by RNA polymerase II rhythmic process | CCAAT-binding factor complex; nucleoplasm; nucleus; protein-DNA complex; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription coregulat... | Mus musculus | Activator Alternative splicing Biological rhythms Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MEQYTTNSNS | MEQYTTNSNSSTEQIVVQAGQIQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQVTVPVSGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSP... | positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of histone acetylation regulation of transcription by RNA polymerase II rhythmic process CCAAT-binding factor complex; nucleoplasm; nucleus; protein-DNA compl... |
heme catabolic process heme oxidation response to hypoxia response to oxidative stress | endoplasmic reticulum membrane; plasma membrane | heme binding heme oxygenase (decyclizing) activity metal ion binding | Rattus norvegicus | Acetylation Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Oxidoreductase Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix | MSSEVETSEG | MSSEVETSEGVDESENNSTAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKEALIKDMEYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLSMKTKERIVEEANKAFEYNMQIFSELDQAGSMLTKETLEDGLPVHDGKGDVRKCPFYAAQPDKGTLGGSNCPFRTAMAVLRKPSLQLILAASVALVAGLLAWYYM | heme catabolic process heme oxidation response to hypoxia response to oxidative stress endoplasmic reticulum membrane; plasma membrane heme binding heme oxygenase (decyclizing) activity metal ion binding Rattus norvegicus Acetylation Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Micro... |
L-serine biosynthetic process L-serine metabolic process lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate pyridoxal phosphate biosynthetic process pyridoxine biosynthetic process | cytoplasm; cytosol | O-phospho-L-serine:2-oxoglutarate aminotransferase activity protein homodimerization activity pyridoxal phosphate binding | Escherichia coli | 3D-structure Amino-acid biosynthesis Aminotransferase Cytoplasm Direct protein sequencing Pyridoxal phosphate Pyridoxine biosynthesis Reference proteome Serine biosynthesis Transferase | MAQIFNFSSG | MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAIDETPDFGADVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAA... | L-serine biosynthetic process L-serine metabolic process lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate pyridoxal phosphate biosynthetic process pyridoxine biosynthetic process cytoplasm; cytosol O-phospho-L-serine:2-oxoglutarate aminotransferase activity protein homodimerization ... |
cellular response to insulin stimulus insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway intracellular glucose homeostasis negative regulation of apoptotic process phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol phosphate biosynthetic process... | nucleus; phosphatidylinositol 3-kinase complex; phosphatidylinositol 3-kinase complex, class IA | 1-phosphatidylinositol-3-kinase regulator activity enzyme-substrate adaptor activity ErbB-3 class receptor binding identical protein binding insulin receptor binding insulin receptor substrate binding insulin-like growth factor receptor binding phosphatidylinositol 3-kinase activator activity phosphatidylinositol 3-kin... | Bos taurus | 3D-structure Acetylation Phosphoprotein Protein transport Reference proteome Repeat SH2 domain SH3 domain Stress response Transport Ubl conjugation | MSAEGYQYRA | MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEAKPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGPSKTEADSEQQASTLPDLAEQFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDTASLDLEMFDVHVLADAFKRYLLDLPNPVIPVAVSSELISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSELFSPLLFRFPAASSENTEHLIKIIEILISTEWNERQPAPALPPKPPKPTTVANN... | cellular response to insulin stimulus insulin receptor signaling pathway insulin-like growth factor receptor signaling pathway intracellular glucose homeostasis negative regulation of apoptotic process phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol phosphate biosynthetic process... |
catecholamine biosynthetic process histamine biosynthetic process histamine metabolic process histidine catabolic process histidine metabolic process | cytoplasm; dendrite; neuronal cell body | amino acid binding histidine decarboxylase activity identical protein binding pyridoxal phosphate binding | Mus musculus | Catecholamine biosynthesis Decarboxylase Direct protein sequencing Lyase Pyridoxal phosphate Reference proteome | MMEPCEYREY | MMEPCEYREYREYYRARGKEMVDYISQYLSTVRERQVTPNVQPGYLRAQLPASAPEEPDSWDSIFGDIERVIMPGVVHWQSPHMHAYYPALTSWPSLLGDMLADAINCLGFTWASSPACTELEMNIMDWLAKMLGLPEYFLHHHPSSRGGGVLQSTVSESTLIALLAARKNKILAMKACEPDANESSLNARLVAYTSDQAHSSVEKAGLISLVKIRFLPVDDNFSLRGEALQKAIEEDKQQGLVPVFVCATLGTTGVCAFDRLSELGPICASEGLWLHVDAAYAGTAFLCPELRGFLEGIEYADSFTFNPSKWMMVHFDC... | catecholamine biosynthetic process histamine biosynthetic process histamine metabolic process histidine catabolic process histidine metabolic process cytoplasm; dendrite; neuronal cell body amino acid binding histidine decarboxylase activity identical protein binding pyridoxal phosphate binding Mus musculus Catecholami... |
diacylglycerol metabolic process glycerolipid metabolic process intracellular signal transduction lipid phosphorylation phosphatidic acid biosynthetic process platelet activation protein kinase C-activating G protein-coupled receptor signaling pathway | cytosol; membrane; plasma membrane | alkylglycerol kinase activity ATP binding ATP-dependent diacylglycerol kinase activity calcium ion binding kinase activity lipid binding phospholipid binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Calcium Cytoplasm Kinase Lipid metabolism Metal-binding Nucleotide-binding Reference proteome Repeat Transferase Zinc Zinc-finger | MAKERGLISP | MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAVGHECD... | diacylglycerol metabolic process glycerolipid metabolic process intracellular signal transduction lipid phosphorylation phosphatidic acid biosynthetic process platelet activation protein kinase C-activating G protein-coupled receptor signaling pathway cytosol; membrane; plasma membrane alkylglycerol kinase activity ATP... |
adult feeding behavior anatomical structure development antennal morphogenesis cell differentiation imaginal disc-derived leg morphogenesis imaginal disc-derived wing morphogenesis male courtship behavior nervous system development regulation of transcription by RNA polymerase II response to water sensory organ develop... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Neurogenesis Nucleus Paired box Reference proteome Transcription Transcription regulation | MPHTGQAGVN | MPHTGQAGVNQLGGVFVNGRPLPDCVRRRIVDLALCGVRPCDISRQLLVSHGCVSKILTRFYETGSIRPGSIGGSKTKQVATPTVVKKIIRLKEENSGMFAWEIREQLQQQRVCDPSSVPSISSINRILRNSGLWTDEMTSSQQNAAAAAAAAAAAAHQAGSGPSNGYGGQAPPPPVTVAPPTPAATPSIARYAKPPALMMNSAGEMPIKPAPKMPPSMGHGHSHGLNPNVSGLDLSYSALHKHWLWNPSLLYYTQAHIQAQAAASGGQFLPYAGGYLPHAMAAAAASSTSALGGFTKSESSIDLSTPGAAGDALSDCDS... | adult feeding behavior anatomical structure development antennal morphogenesis cell differentiation imaginal disc-derived leg morphogenesis imaginal disc-derived wing morphogenesis male courtship behavior nervous system development regulation of transcription by RNA polymerase II response to water sensory organ develop... |
anatomical structure development anatomical structure morphogenesis muscle organ development negative regulation of apoptotic process regulation of transcription by RNA polymerase II | chromatin; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Alternative splicing Chromosomal rearrangement Developmental protein Disease variant DNA-binding Homeobox Myogenesis Nucleus Paired box Proto-oncogene Reference proteome Transcription Transcription regulation | MAALPGTVPR | MAALPGTVPRMMRPAPGQNYPRTGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNHLLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGG... | anatomical structure development anatomical structure morphogenesis muscle organ development negative regulation of apoptotic process regulation of transcription by RNA polymerase II chromatin; nucleus DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA po... |
anatomical structure development animal organ morphogenesis apoptotic process muscle organ development nervous system development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sensory perception of sound | chromatin; nucleoplasm | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific HMG box domain binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | 3D-structure Alternative splicing Chromosomal rearrangement Deafness Developmental protein Disease variant DNA-binding Homeobox Myogenesis Neurogenesis Nucleus Paired box Phosphoprotein Proto-oncogene Reference proteome Transcription Transcription regulation Waardenburg syndrome | MTTLAGAVPR | MTTLAGAVPRMMRPGPGQNYPRSGFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFGKGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQA... | anatomical structure development animal organ morphogenesis apoptotic process muscle organ development nervous system development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sensory perception of sound chro... |
SNARE complex assembly vesicle fusion | cytosol; mitochondrial outer membrane; neuron projection; plasma membrane; SNARE complex; specific granule membrane; synaptic vesicle membrane; tertiary granule membrane | SNAP receptor activity syntaxin binding | Homo sapiens | Alternative splicing Coiled coil Congenital myasthenic syndrome Cytoplasmic vesicle Disease variant Membrane Mitochondrion Mitochondrion outer membrane Neurodegeneration Phosphoprotein Reference proteome Synapse Synaptosome Transmembrane Transmembrane helix | MSAPAQPPAE | MSAPAQPPAEGTEGTAPGGGPPGPPPNMTSNRRLQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYFFT | SNARE complex assembly vesicle fusion cytosol; mitochondrial outer membrane; neuron projection; plasma membrane; SNARE complex; specific granule membrane; synaptic vesicle membrane; tertiary granule membrane SNAP receptor activity syntaxin binding Homo sapiens Alternative splicing Coiled coil Congenital myasthenic synd... |
hydrogen peroxide catabolic process response to corticosterone response to molecule of fungal origin response to organic cyclic compound response to organic substance response to oxidative stress response to selenium ion response to xenobiotic stimulus | extracellular space | glutathione peroxidase activity identical protein binding mercury ion binding selenium binding | Rattus norvegicus | Oxidoreductase Peroxidase Reference proteome Secreted Selenocysteine Signal | MARILRASCL | MARILRASCLLSLLLAGFVPPGRGQEKSKTDCHGGMSGTIYEYGALTIDGEEYIPFKQYAGKYILFVNVASYUGLTDQYLELNALQEELGPFGLVILGFPCNQFGKQEPGENSEILPSLKYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTAELLGSPGRLFWEPMKIHDIRWNFEKFLVGPDGIPIMRWYHRTTVSNVKMDILSYMRRQAALGARGK | hydrogen peroxide catabolic process response to corticosterone response to molecule of fungal origin response to organic cyclic compound response to organic substance response to oxidative stress response to selenium ion response to xenobiotic stimulus extracellular space glutathione peroxidase activity identical prote... |
fungal-type cell wall organization glucan catabolic process glucan metabolic process | cell surface; extracellular region; fungal-type cell wall; fungal-type vacuole | glucan exo-1,3-beta-glucosidase activity | Saccharomyces cerevisiae | 3D-structure Cell wall Cell wall biogenesis/degradation Cleavage on pair of basic residues Direct protein sequencing Glycoprotein Glycosidase Hydrolase Reference proteome Secreted Signal | MLSLKTLLCT | MLSLKTLLCTLLTVSSVLATPVPARDPSSIQFVHEENKKRYYDYDHGSLGEPIRGVNIGGWLLLEPYITPSLFEAFRTNDDNDEGIPVDEYHFCQYLGKDLAKSRLQSHWSTFYQEQDFANIASQGFNLVRIPIGYWAFQTLDDDPYVSGLQESYLDQAIGWARNNSLKVWVDLHGAAGSQNGFDNSGLRDSYKFLEDSNLAVTTNVLNYILKKYSAEEYLDTVIGIELINEPLGPVLDMDKMKNDYLAPAYEYLRNNIKSDQVIIIHDAFQPYNYWDDFMTENDGYWGVTIDHHHYQVFASDQLERSIDEHIKVACEWG... | fungal-type cell wall organization glucan catabolic process glucan metabolic process cell surface; extracellular region; fungal-type cell wall; fungal-type vacuole glucan exo-1,3-beta-glucosidase activity Saccharomyces cerevisiae 3D-structure Cell wall Cell wall biogenesis/degradation Cleavage on pair of basic residue... |
carbohydrate metabolic process galactose catabolic process response to cortisone response to Thyroglobulin triiodothyronine | cytoplasm; extracellular space; Golgi apparatus; intracellular membrane-bounded organelle; lysosome; vacuole | beta-galactosidase activity galactoside binding hydrolase activity protein homodimerization activity | Mus musculus | 3D-structure Disulfide bond Glycoprotein Glycosidase Hydrolase Lysosome Reference proteome Signal Zymogen | MLRVPLCTPL | MLRVPLCTPLPLLALLQLLGAAHGIYNVTQRTFKLDYSRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKQSIVLRSSDPDYLVAVDKWLAVLLPKMKPLLYQNGGPIITVQVENEYGSYFACDYDYLRFLVHRFRYHLGNDVILFTTDGASEKMLKCGTLQDLYATVDFGTGNNITQAFLVQRKFEPKGPLINSEFYTGWLDHWGKPHSTVKTKTLATSLYNLLARGANVNLYMFIGGTNFAYWNG... | carbohydrate metabolic process galactose catabolic process response to cortisone response to Thyroglobulin triiodothyronine cytoplasm; extracellular space; Golgi apparatus; intracellular membrane-bounded organelle; lysosome; vacuole beta-galactosidase activity galactoside binding hydrolase activity protein homodimeriza... |
carnitine metabolic process carnitine shuttle fatty acid beta-oxidation in utero embryonic development long-chain fatty acid metabolic process positive regulation of cold-induced thermogenesis | mitochondrial inner membrane; mitochondrion; nucleolus; nucleoplasm | acyltransferase activity carnitine O-octanoyltransferase activity carnitine O-palmitoyltransferase activity | Homo sapiens | Acetylation Acyltransferase Direct protein sequencing Disease variant Fatty acid metabolism Lipid metabolism Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transferase Transit peptide Transport | MVPRLLLRAW | MVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDTIRRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTRATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKARHLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDS... | carnitine metabolic process carnitine shuttle fatty acid beta-oxidation in utero embryonic development long-chain fatty acid metabolic process positive regulation of cold-induced thermogenesis mitochondrial inner membrane; mitochondrion; nucleolus; nucleoplasm acyltransferase activity carnitine O-octanoyltransferase ac... |
autophagosome maturation autophagy cellular response to arsenite ion cellular response to heat DNA damage response DNA repair double-strand break repair endoplasmic reticulum stress-induced pre-emptive quality control endosome to lysosome transport via multivesicular body sorting pathway ERAD pathway interstrand cross-... | chromatin; cytoplasm; cytoplasmic stress granule; cytosol; endoplasmic reticulum; nucleus; site of double-strand break | ATP binding ATP hydrolysis activity identical protein binding lipid binding protein-containing complex binding | Xenopus laevis | ATP-binding Autophagy Cytoplasm Direct protein sequencing DNA damage DNA repair Endoplasmic reticulum Hydrolase Lipid-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transport | MASGSDTKSD | MASGSDTKSDDLSTAILKQKSRPNRLIVDESINEDNSMVSLSQAKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRVHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV... | autophagosome maturation autophagy cellular response to arsenite ion cellular response to heat DNA damage response DNA repair double-strand break repair endoplasmic reticulum stress-induced pre-emptive quality control endosome to lysosome transport via multivesicular body sorting pathway ERAD pathway interstrand cross-... |
cardiac muscle cell differentiation cellular response to acidic pH cellular response to epinephrine stimulus intracellular sodium ion homeostasis positive regulation of calcineurin-NFAT signaling cascade positive regulation of cardiac muscle hypertrophy positive regulation of the force of heart contraction positive reg... | apical plasma membrane; basolateral plasma membrane; cation-transporting ATPase complex; cytoplasm; membrane raft; nucleoplasm; plasma membrane | calcium-dependent protein binding calmodulin binding identical protein binding phospholipid binding protein phosphatase 2B binding sodium:proton antiporter activity | Oryctolagus cuniculus | Antiport Calmodulin-binding Cell membrane Glycoprotein Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Sodium Sodium transport Transmembrane Transmembrane helix Transport Ubl conjugation | MLLWSAVRGL | MLLWSAVRGLSPPRIVPSLLVVVALAGLLPGLRSHGLQLSPTDSTTPDSQPSRERSIGDVTTAPPEVTPESRPVNRSVTEHGMKPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGEKPPFLQSEVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYDHVGIVDIVLGFLSFFVVALGGVFVGVVYGVIAAFTS... | cardiac muscle cell differentiation cellular response to acidic pH cellular response to epinephrine stimulus intracellular sodium ion homeostasis positive regulation of calcineurin-NFAT signaling cascade positive regulation of cardiac muscle hypertrophy positive regulation of the force of heart contraction positive reg... |
antennal development brain development circadian rhythm eclosion rhythm leg disc proximal/distal pattern formation locomotor rhythm photoreceptor cell maintenance positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regula... | nucleus | DNA binding metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein DNA-binding Metal-binding Nucleus Reference proteome Repeat Sensory transduction Vision Zinc Zinc-finger | MEHIMNPFMS | MEHIMNPFMSPAYLLGHGPHSHQHVHSHLPSHPQPNAASPASSPGGSSGSGSGSAAGSGTGSGSSLKPRRWGSPPINLAGQFINPATGKKRVQCSICFKTFCDKGALKIHFSAVHLREMHKCTVEGCNMVFSSRRSRNRHSANPNPKLHSPHIRRKISPHDGRTAQQFPVFSPGTAAAAAAVAGRLPVAFPGLLPPPPPHHGHHPYVMFGGQAGLHGLGLLSTGCQDPDSGSVDNEQDADPEDDNDFVYVDMQANSSSPAASSEDQEEHERDNEQDEEMHCSLSLASSSSIAADEERAADQPLDFSLHKRRKSEQDREQE... | antennal development brain development circadian rhythm eclosion rhythm leg disc proximal/distal pattern formation locomotor rhythm photoreceptor cell maintenance positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regula... |
acetylcholine catabolic process choline metabolic process | extracellular space; plasma membrane; side of membrane; synapse | acetylcholinesterase activity amyloid-beta binding | Bos taurus | Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Neurotransmitter degradation Reference proteome Secreted Serine esterase Signal Synapse | MRPPWCPLHT | MRPPWCPLHTPSLTPPLLLLLFLIGGGAEAEGPEDPELLVMVRGGRLRGLRLMAPRGPVSAFLGIPFAEPPVGPRRFLPPEPKRPWPGVLNATAFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPSSPTPVLVWIYGGGFYSGASSLDVYDGRFLTQAEGTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGVGEARRRATLLARLVGCPPGGAGGNDTELVACLRARPAQDLVDHEWRVLP... | acetylcholine catabolic process choline metabolic process extracellular space; plasma membrane; side of membrane; synapse acetylcholinesterase activity amyloid-beta binding Bos taurus Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Neuro... |
anterior/posterior pattern specification apoptotic signaling pathway cellular response to hydrogen peroxide chromatin organization chromatin remodeling embryonic skeletal system development embryonic skeletal system morphogenesis in utero embryonic development negative regulation of apoptotic signaling pathway negative... | chromatin; nuclear body; nucleoplasm; nucleus; PcG protein complex; PRC1 complex; sex chromatin | chromatin binding DNA binding metal ion binding promoter-specific chromatin binding | Mus musculus | DNA-binding Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MHRTTRIKIT | MHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALGDDEIVSLSIEFYEGVRDREEKKNLTENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEILYEDEPLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRLTLPTVPTPSEGTNTSGASECESVSDKAPSPATLPATSSSLPSPATPSHGSPSSHGPPATHPTSPTPPSTAAGTTTATNGGTSNC... | anterior/posterior pattern specification apoptotic signaling pathway cellular response to hydrogen peroxide chromatin organization chromatin remodeling embryonic skeletal system development embryonic skeletal system morphogenesis in utero embryonic development negative regulation of apoptotic signaling pathway negative... |
blastoderm segmentation embryonic hindgut morphogenesis embryonic pattern specification imaginal disc-derived leg joint morphogenesis Malpighian tubule morphogenesis negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II pattern specification process periodic partit... | nucleus | DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Activator Developmental protein DNA-binding Metal-binding Nucleus Pair-rule protein Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MSSTSASPIS | MSSTSASPISNITVDDELNLSREQDFAEEDFIVIKEERETSLSPMLTPPHTPTEEPLRRVHPAISEEAVATQLHMRHMAHYQQQQQQQQQQQQHRLWLQMQQQQQQHQAPQQYPVYPTASADPVAVHQQLMNHWIRNAAIYQQQQQQQQHPHHHHHHGHPHHPHPHPHHVRPYPAGLHSLHAAVMGRHFGAMPTLKLGGAGGASGVPSGATGSSRPKKQFICKYCNRQFTKSYNLLIHERTHTDERPYSCDICGKAFRRQDHLRDHRYIHSKDKPFKCSDCGKGFCQSRTLAVHKVTHLEEGPHKCPICQRSFNQRANLK... | blastoderm segmentation embryonic hindgut morphogenesis embryonic pattern specification imaginal disc-derived leg joint morphogenesis Malpighian tubule morphogenesis negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II pattern specification process periodic partit... |
extracellular matrix organization | collagen trimer; collagen-containing extracellular matrix; extracellular space | extracellular matrix structural constituent conferring tensile strength mannose binding | Bos taurus | 3D-structure Calcium Collagen Direct protein sequencing Disulfide bond Glycoprotein Hydroxylation Lectin Mannose-binding Reference proteome Repeat Signal | MLLLPLSVLL | MLLLPLSVLLLLTQPWRSLGAEMTTFSQKILANACTLVMCSPLESGLPGHDGQDGRECPHGEKGDPGSPGPAGRAGRPGWVGPIGPKGDNGFVGEPGPKGDTGPRGPPGMPGPAGREGPSGKQGSMGPPGTPGPKGETGPKGGVGAPGIQGFPGPSGLKGEKGAPGETGAPGRAGVTGPSGAIGPQGPSGARGPPGLKGDRGDPGETGAKGESGLAEVNALKQRVTILDGHLRRFQNAFSQYKKAVLFPDGQAVGEKIFKTAGAVKSYSDAEQLCREAKGQLASPRSSAENEAVTQMVRAQEKNAYLSMNDISTEGRFTY... | extracellular matrix organization collagen trimer; collagen-containing extracellular matrix; extracellular space extracellular matrix structural constituent conferring tensile strength mannose binding Bos taurus 3D-structure Calcium Collagen Direct protein sequencing Disulfide bond Glycoprotein Hydroxylation Lectin Man... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell surface receptor signaling pathway diet induced thermogenesis G protein-coupled receptor signaling pathway intracellular water homeostasis positive regulation of cAMP-mediated signaling positive regulation of lipid catabolic process regulati... | cytoplasmic microtubule; plasma membrane | G protein-coupled peptide receptor activity peptide binding peptide hormone binding secretin receptor activity | Rattus norvegicus | Cell membrane G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Signal Transducer Transmembrane Transmembrane helix | MLSTMRPRLS | MLSTMRPRLSLLLLRLLLLTKAAHTVGVPPRLCDVRRVLLEERAHCLQQLSKEKKGALGPETASGCEGLWDNMSCWPSSAPARTVEVQCPKFLLMLSNKNGSLFRNCTQDGWSETFPRPDLACGVNINNSFNERRHAYLLKLKVMYTVGYSSSLAMLLVALSILCSFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFSSDDVTYCDAHKVGCKLVMIFFQYCIMANYAWLLVEGLYLHTLLAISFFSERKYLQAFVLLGWGSPAIFVALWAITRHFLENTGCWDINANASVWWVIRGPVILSILINFIFFINILRIL... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell surface receptor signaling pathway diet induced thermogenesis G protein-coupled receptor signaling pathway intracellular water homeostasis positive regulation of cAMP-mediated signaling positive regulation of lipid catabolic process regulati... |
anatomical structure development anterior/posterior pattern specification branching involved in ureteric bud morphogenesis cartilage development involved in endochondral bone morphogenesis cell development chondrocyte development chondrocyte differentiation developmental growth dorsal/ventral pattern formation embryoni... | nucleoplasm; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MYLPGCAYYV | MYLPGCAYYVAPSDFASKPSFLSQPSSCQMTFPYSSNLAPHVQPVREVAFRDYGLERAKWPYRGGGGGGAGGGGGGGPGGGGGGSGGYAPYYAAAAAAAAAAAAAEEAAMQRDLLPPAGRRPDVLFKAPEPVCGAPGPPHGPAAAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPQPAPAPPQPEGAADKGDPKPGAGGGGGSPCAKATPGPEPKGAAEGGGGEGEGPPGEAGAEKSGGTVAPQRSRKKRCPYTKYQIRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGN... | anatomical structure development anterior/posterior pattern specification branching involved in ureteric bud morphogenesis cartilage development involved in endochondral bone morphogenesis cell development chondrocyte development chondrocyte differentiation developmental growth dorsal/ventral pattern formation embryoni... |
cellular response to amine stimulus cellular response to amino acid stimulus cellular response to ammonium ion cellular response to brain-derived neurotrophic factor stimulus cellular response to dsRNA cellular response to peptide hormone stimulus cerebral cortex development chemical synaptic transmission long-term mem... | AMPA glutamate receptor complex; asymmetric synapse; axonal spine; cell body; cell surface; cell-cell junction; dendrite; dendrite membrane; dendritic shaft; dendritic spine; dendritic spine membrane; early endosome; early endosome membrane; endoplasmic reticulum; endoplasmic reticulum membrane; excitatory synapse; glu... | adenylate cyclase binding AMPA glutamate receptor activity amyloid-beta binding beta-2 adrenergic receptor binding G-protein alpha-subunit binding G-protein beta-subunit binding glutamate receptor binding glutamate-gated receptor activity identical protein binding immunoglobulin binding ionotropic glutamate receptor bi... | Mus musculus | 3D-structure Cell membrane Cell projection Disulfide bond Endoplasmic reticulum Endosome Glycoprotein Ion channel Ion transport Ligand-gated ion channel Lipoprotein Membrane Palmitate Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MPYIFAFFCT | MPYIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNA... | cellular response to amine stimulus cellular response to amino acid stimulus cellular response to ammonium ion cellular response to brain-derived neurotrophic factor stimulus cellular response to dsRNA cellular response to peptide hormone stimulus cerebral cortex development chemical synaptic transmission long-term mem... |
cellular response to brain-derived neurotrophic factor stimulus cellular response to glycine chemical synaptic transmission establishment of protein localization ionotropic glutamate receptor signaling pathway modulation of chemical synaptic transmission positive regulation of synaptic transmission protein tetramerizat... | AMPA glutamate receptor complex; asymmetric synapse; axon; cell surface; dendrite; dendrite cytoplasm; dendrite membrane; dendritic shaft; dendritic spine; dendritic spine head; dendritic spine neck; endoplasmic reticulum; endoplasmic reticulum membrane; glutamatergic synapse; growth cone; membrane; neuron projection; ... | AMPA glutamate receptor activity amyloid-beta binding cytoskeletal protein binding extracellularly glutamate-gated ion channel activity glutamate receptor binding glutamate-gated receptor activity identical protein binding immunoglobulin binding ionotropic glutamate receptor binding kainate selective glutamate receptor... | Mus musculus | 3D-structure Alternative splicing Cell membrane Disulfide bond Endoplasmic reticulum Glycoprotein Ion channel Ion transport Ligand-gated ion channel Lipoprotein Membrane Palmitate Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome RNA editing Signal Synapse Transmembrane Transmembrane helix Transport... | MQKIMHISVL | MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIE... | cellular response to brain-derived neurotrophic factor stimulus cellular response to glycine chemical synaptic transmission establishment of protein localization ionotropic glutamate receptor signaling pathway modulation of chemical synaptic transmission positive regulation of synaptic transmission protein tetramerizat... |
positive regulation of DNA-templated transcription regulation of DNA-templated transcription | cytosol; protein-DNA complex | DNA-binding transcription activator activity identical protein binding phosphorelay response regulator activity transcription cis-regulatory region binding | Escherichia coli | 3D-structure Activator Cytoplasm Direct protein sequencing DNA-binding Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Two-component regulatory system | MRVLVVEDNA | MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGYLFELR | positive regulation of DNA-templated transcription regulation of DNA-templated transcription cytosol; protein-DNA complex DNA-binding transcription activator activity identical protein binding phosphorelay response regulator activity transcription cis-regulatory region binding Escherichia coli 3D-structure Activator Cy... |
cellular response to magnesium starvation osmosensory signaling via phosphorelay pathway phosphorelay signal transduction system signal transduction | plasma membrane | ATP binding identical protein binding kinase activity metal ion binding phosphoprotein phosphatase activity phosphorelay sensor kinase activity | Escherichia coli | 3D-structure ATP-binding Cell inner membrane Cell membrane Direct protein sequencing Hydrolase Kinase Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Protein phosphatase Reference proteome Transferase Transmembrane Transmembrane helix Two-component regulatory system | MKKLLRLFFP | MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSFDKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDVPWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVAVNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSLRPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLTHSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGY... | cellular response to magnesium starvation osmosensory signaling via phosphorelay pathway phosphorelay signal transduction system signal transduction plasma membrane ATP binding identical protein binding kinase activity metal ion binding phosphoprotein phosphatase activity phosphorelay sensor kinase activity Escherichia... |
hydrogen sulfide biosynthetic process sulfate assimilation sulfate reduction sulfur compound metabolic process | sulfate adenylyltransferase complex (ATP) | ATP binding GTP binding GTPase activity sulfate adenylyltransferase (ATP) activity | Escherichia coli | ATP-binding Direct protein sequencing GTP-binding Nucleotide-binding Nucleotidyltransferase Reference proteome Transferase | MNTALAQQIA | MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISR... | hydrogen sulfide biosynthetic process sulfate assimilation sulfate reduction sulfur compound metabolic process sulfate adenylyltransferase complex (ATP) ATP binding GTP binding GTPase activity sulfate adenylyltransferase (ATP) activity Escherichia coli ATP-binding Direct protein sequencing GTP-binding Nucleotide-bindin... |
chaperone-mediated protein folding chemotaxis dipeptide transport heme transmembrane transport protein transport | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; outer membrane-bounded periplasmic space | dipeptide transmembrane transporter activity heme binding peptide binding peptide transmembrane transporter activity | Escherichia coli | 3D-structure Chemotaxis Direct protein sequencing Disulfide bond Peptide transport Periplasm Protein transport Reference proteome Signal Transport | MRISLKKSGM | MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWHDNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDDNTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKD... | chaperone-mediated protein folding chemotaxis dipeptide transport heme transmembrane transport protein transport ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane; outer membrane-bounded periplasmic space dipeptide transmembrane transporter activity heme binding peptide bind... |
protein catabolic process proteolysis response to antibiotic signal transduction | outer membrane-bounded periplasmic space; plasma membrane | endopeptidase activity serine-type endopeptidase activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Hydrolase Membrane Protease Reference proteome Serine protease Signal | MNMFFRLTAL | MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEIL... | protein catabolic process proteolysis response to antibiotic signal transduction outer membrane-bounded periplasmic space; plasma membrane endopeptidase activity serine-type endopeptidase activity Escherichia coli 3D-structure Cell inner membrane Cell membrane Hydrolase Membrane Protease Reference proteome Serine prote... |
DNA-templated transcription negative regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of growth | protein-DNA complex; toxin-antitoxin complex | core promoter sequence-specific DNA binding DNA-binding transcription repressor activity protein homodimerization activity sequence-specific DNA binding transcription cis-regulatory region binding | Escherichia coli | 3D-structure Direct protein sequencing DNA-binding Reference proteome Repressor Toxin-antitoxin system Transcription Transcription regulation | MMSFQKIYSP | MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDAKNASPESTEQQNLEW | DNA-templated transcription negative regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of growth protein-DNA complex; toxin-antitoxin complex core promoter sequence-specific DNA binding DNA-binding transcription repressor activity protein homodimerization activity sequence-s... |
dormancy process phosphorylation regulation of DNA-templated transcription regulation of growth response to antibiotic single-species biofilm formation | cytosol; protein-DNA complex; toxin-antitoxin complex | ATP binding DNA-binding transcription repressor activity magnesium ion binding protein serine kinase activity protein serine/threonine kinase activity sequence-specific DNA binding transcription cis-regulatory region binding | Escherichia coli | 3D-structure Antibiotic resistance ATP-binding Direct protein sequencing DNA-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Repressor Serine/threonine-protein kinase Toxin-antitoxin system Transferase | MPKLVTWMNN | MPKLVTWMNNQRVGELTKLANGAHTFKYAPEWLASRYARPLSLSLPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVTLIPEDETVTHPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTALLRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVPDAEIIKAGNVRALAVERFDRRWNAERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIARIMAFLMGSSEALKDRYDFMKFQVFQWLIGATDGHAKNFSVFIQ... | dormancy process phosphorylation regulation of DNA-templated transcription regulation of growth response to antibiotic single-species biofilm formation cytosol; protein-DNA complex; toxin-antitoxin complex ATP binding DNA-binding transcription repressor activity magnesium ion binding protein serine kinase activity prot... |
cell division chromosome segregation positive regulation of establishment of cell polarity regulating cell shape regulation of mitotic cell cycle signaling | chromatin; cytoplasm; nucleolus; nucleus; protein phosphatase type 1 complex; PTW/PP1 phosphatase complex | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Schizosaccharomyces pombe | Cell cycle Cell division Hydrolase Manganese Metal-binding Mitosis Protein phosphatase Reference proteome | MDYDIDAIIE | MDYDIDAIIEKLVKARNGKPSKQVQLSDAEIRYLCTTSRSIFLSQPMLLELEAPLKICGDIHGQYSDLLRLFEYGGYPPDANYLFLGDYVDRGKQSLEVICLLFAYKIKYPENFFLLRGNHEFASINRIYGFYDECKRRYSIKLWKTFTDCFNCMPVAAVIDEKIFCMHGGLSPDLNSLDQIQRIIRPTDIPDTGLLCDLVWSDPEKDLTGWGENDRGVSYTFGADVVSRFLQKHDLDLICRAHQVVEDGYEFFGKRQLVTIFSAPNYCGEFDNVGAMMSVNEDLLCSFQILKPAEKRQRVSQSSIKESKSATNSLKKSK... | cell division chromosome segregation positive regulation of establishment of cell polarity regulating cell shape regulation of mitotic cell cycle signaling chromatin; cytoplasm; nucleolus; nucleus; protein phosphatase type 1 complex; PTW/PP1 phosphatase complex metal ion binding myosin phosphatase activity protein seri... |
charged-tRNA amino acid modification conversion of methionyl-tRNA to N-formyl-methionyl-tRNA | cytosol | methionyl-tRNA formyltransferase activity | Escherichia coli | 3D-structure Direct protein sequencing Protein biosynthesis Reference proteome Transferase | MSESLRIIFA | MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVAELQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV | charged-tRNA amino acid modification conversion of methionyl-tRNA to N-formyl-methionyl-tRNA cytosol methionyl-tRNA formyltransferase activity Escherichia coli 3D-structure Direct protein sequencing Protein biosynthesis Reference proteome Transferase MSESLRIIFA MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEE... |
cell redox homeostasis cysteine export across plasma membrane glutathione transmembrane transport regulation of heme biosynthetic process | ATP-binding cassette (ABC) transporter complex; membrane; plasma membrane | ABC-type transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity | Escherichia coli | 3D-structure Amino-acid transport ATP-binding Cell inner membrane Cell membrane Membrane Nucleotide-binding Reference proteome Translocase Transmembrane Transmembrane helix Transport | MRALLPYLAL | MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRISDLTDQ... | cell redox homeostasis cysteine export across plasma membrane glutathione transmembrane transport regulation of heme biosynthetic process ATP-binding cassette (ABC) transporter complex; membrane; plasma membrane ABC-type transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter a... |
positive regulation of DNA-templated transcription regulation of DNA-templated transcription | cytosol; plasma membrane; protein-DNA complex | phosphorelay response regulator activity protein homodimerization activity transcription cis-regulatory region binding | Escherichia coli | 3D-structure Activator Cell inner membrane Cell membrane Disulfide bond DNA-binding Membrane Reference proteome Transcription Transcription regulation Transmembrane Transmembrane helix | MQQPVVRVGE | MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFWVWFFFLLSLGICVALVAFSSLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQ... | positive regulation of DNA-templated transcription regulation of DNA-templated transcription cytosol; plasma membrane; protein-DNA complex phosphorelay response regulator activity protein homodimerization activity transcription cis-regulatory region binding Escherichia coli 3D-structure Activator Cell inner membrane Ce... |
protoporphyrinogen IX biosynthetic process | cytosol | glutamate-1-semialdehyde 2,1-aminomutase activity protein homodimerization activity pyridoxal phosphate binding transaminase activity | Escherichia coli | Cytoplasm Isomerase Porphyrin biosynthesis Pyridoxal phosphate Reference proteome | MSKSENLYSA | MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKYTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPEFLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGV... | protoporphyrinogen IX biosynthetic process cytosol glutamate-1-semialdehyde 2,1-aminomutase activity protein homodimerization activity pyridoxal phosphate binding transaminase activity Escherichia coli Cytoplasm Isomerase Porphyrin biosynthesis Pyridoxal phosphate Reference proteome MSKSENLYSA MSKSENLYSAARELIPGGVNSPVRA... |
proteolysis response to temperature stimulus | membrane; plasma membrane | metalloendopeptidase activity zinc ion binding | Escherichia coli | Autocatalytic cleavage Cell inner membrane Cell membrane Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Stress response Transmembrane Transmembrane helix Zinc | MMRIALFLLT | MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMALCINGKSKSLSELFMTHPPLDKRIEALRTGEYLK | proteolysis response to temperature stimulus membrane; plasma membrane metalloendopeptidase activity zinc ion binding Escherichia coli Autocatalytic cleavage Cell inner membrane Cell membrane Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Stress response Transmembrane Transmembrane helix Z... |
cellular response to xenobiotic stimulus choline transport DNA damage response glycine betaine transport response to osmotic stress response to xenobiotic stimulus transmembrane transport xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic metabolic process xenobiotic transport | EmrE multidrug transporter complex; membrane; plasma membrane | amino-acid betaine transmembrane transporter activity antiporter activity choline transmembrane transporter activity identical protein binding transmembrane transporter activity xenobiotic transmembrane transporter activity | Escherichia coli | 3D-structure Antiport Cell inner membrane Cell membrane Membrane Reference proteome Transmembrane Transmembrane helix Transport | MNPYIYLGGA | MNPYIYLGGAILAEVIGTTLMKFSEGFTRLWPSVGTIICYCASFWLLAQTLAYIPTGIAYAIWSGVGIVLISLLSWGFFGQRLDLPAIIGMMLICAGVLIINLLSRSTPH | cellular response to xenobiotic stimulus choline transport DNA damage response glycine betaine transport response to osmotic stress response to xenobiotic stimulus transmembrane transport xenobiotic detoxification by transmembrane export across the plasma membrane xenobiotic metabolic process xenobiotic transport EmrE ... |
acetate transport arsenite transport conjugation with cellular fusion glycerol metabolic process glycerol transmembrane transport polyol transmembrane transport water transport | cell periphery; cytoplasm; fungal-type vacuole; plasma membrane | glycerol channel activity glycerol transmembrane transporter activity water channel activity | Saccharomyces cerevisiae | Glycerol metabolism Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport | MSNPQKALND | MSNPQKALNDFLSSESVHTHDSSRKQSNKQSSDEGRSSSQPSHHHSGGTNNNNNNNNNNNNSNNNNNGNDGGNDDDYDYEMQDYRPSPQSARPTPTYVPQYSVESGTAFPIQEVIPSAYINTQDINHKDNGPPSASSNRAFRPRGQTTVSANVLNIEDFYKNADDAHTIPESHLSRRRSRSRATSNAGHSANTGATNGRTTGAQTNMESNESPRNVPIMVKPKTLYQNPQTPTVLPSTYHPINKWSSVKNTYLKEFLAEFMGTMVMIIFGSAVVCQVNVAGKIQQDNFNVALDNLNVTGSSAETIDAMKSLTSLVSSVAG... | acetate transport arsenite transport conjugation with cellular fusion glycerol metabolic process glycerol transmembrane transport polyol transmembrane transport water transport cell periphery; cytoplasm; fungal-type vacuole; plasma membrane glycerol channel activity glycerol transmembrane transporter activity water cha... |
defense response to virus immune system process positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II toll-like receptor 3 signaling pathway | cytosol; focal adhesion; nucleoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region seq... | Mus musculus | 3D-structure Acetylation Activator Direct protein sequencing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation | MPVERMRMRP | MPVERMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNWAIHTGKHQPGIDKPDPKTWKANFRCAMNSLPDIEEVKDRSIKKGNNAFRVYRMLPLSERPSKKGKKPKTEKEERVKHIKQEPVESSLGLSNGVSGFSPEYAVLTSAIKNEVDSTVNIIVVGQSHLDSNIEDQEIVTNPPDICQVVEVTTESDDQPVSMSELYPLQISPVSSYAESETTDSVASDEENAEGRPHWRKRSIEGKQYLSNMGTRNTYLLPSMATFVTSNKPDLQVTIKEDSCPMPYNSSWPPFTDLPLPAPVTPT... | defense response to virus immune system process positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II toll-like receptor 3 signaling pathway cytosol; focal adhesion; nucleoplasm; nucleus DNA binding DNA-binding transcription ... |
protein homooligomerization | Golgi apparatus; plasma membrane; side of membrane | copper ion binding identical protein binding microtubule binding tubulin binding | Ovis aries | 3D-structure Amyloid Cell membrane Copper Direct protein sequencing Disease variant Disulfide bond Glycoprotein Golgi apparatus GPI-anchor Lipoprotein Membrane Metal-binding Prion Reference proteome Repeat Signal Zinc | MVKSHIGSWI | MVKSHIGSWILVLFVAMWSDVGLCKKRPKPGGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGGWGQGGSHSQWNKPSKPKTNMKHVAGAAAAGAVVGGLGGYMLGSAMSRPLIHFGNDYEDRYYRENMYRYPNQVYYRPVDRYSNQNNFVHDCVNITVKQHTVTTTTKGENFTETDIKIMERVVEQMCITQYQRESQAYYQRGASVILFSSPPVILLISFLIFLIVG | protein homooligomerization Golgi apparatus; plasma membrane; side of membrane copper ion binding identical protein binding microtubule binding tubulin binding Ovis aries 3D-structure Amyloid Cell membrane Copper Direct protein sequencing Disease variant Disulfide bond Glycoprotein Golgi apparatus GPI-anchor Lipoprotei... |
arginine biosynthetic process | cytoplasm | acetylornithine deacetylase activity cobalt ion binding zinc ion binding | Escherichia coli | 3D-structure Amino-acid biosynthesis Arginine biosynthesis Cobalt Cytoplasm Hydrolase Metal-binding Reference proteome Zinc | MKNKLPPFIE | MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASIGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKL... | arginine biosynthetic process cytoplasm acetylornithine deacetylase activity cobalt ion binding zinc ion binding Escherichia coli 3D-structure Amino-acid biosynthesis Arginine biosynthesis Cobalt Cytoplasm Hydrolase Metal-binding Reference proteome Zinc MKNKLPPFIE MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPV... |
DNA damage response mismatch repair regulation of DNA recombination | cytosol; mismatch repair complex; MutS complex | adenine/cytosine mispair binding ADP binding ATP binding ATP hydrolysis activity ATP-dependent DNA damage sensor activity damaged DNA binding DNA binding, bending identical protein binding mismatched DNA binding | Escherichia coli | 3D-structure ATP-binding DNA damage DNA repair DNA-binding Nucleotide-binding Reference proteome | MSAIENFDAH | MSAIENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRV... | DNA damage response mismatch repair regulation of DNA recombination cytosol; mismatch repair complex; MutS complex adenine/cytosine mispair binding ADP binding ATP binding ATP hydrolysis activity ATP-dependent DNA damage sensor activity damaged DNA binding DNA binding, bending identical protein binding mismatched DNA b... |
cholesterol biosynthetic process neutrophil differentiation | cytoplasm; endoplasmic reticulum membrane; nuclear inner membrane; nucleus | delta14-sterol reductase activity DNA binding NADPH binding | Gallus gallus | 3D-structure Cholesterol biosynthesis Cholesterol metabolism Cytoplasm DNA-binding Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane Nucleus Oxidoreductase Phosphoprotein Receptor Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transmembrane Transmembran... | MPNRKYADGE | MPNRKYADGEVVMGRWPGSVLYYEVQVTSYDDASHLYTVKYKDGTELALKESDIRLQSSFKQRKSQSSSSSPSRRSRSRSRSRSPGRPAKGRRRSSSHSREHKEDKKKIIQETSLAPPKPSENNTRRYNGEPDSTERNDTSSKLLEQQKLKPDVEMERVLDQYSLRSRREEKKKEEIYAEKKIFEAIKTPEKPSSKTKELEFGGRFGTFMLMFFLPATVLYLVLMCKQDDPSLMNFPPLPALESLWETKVFGVFLLWFFFQALFYLLPIGKVVEGLPLSNPRKLQYRINGFYAFLLTAAAIGTLLYFQFELHYLYDHFVQ... | cholesterol biosynthetic process neutrophil differentiation cytoplasm; endoplasmic reticulum membrane; nuclear inner membrane; nucleus delta14-sterol reductase activity DNA binding NADPH binding Gallus gallus 3D-structure Cholesterol biosynthesis Cholesterol metabolism Cytoplasm DNA-binding Endoplasmic reticulum Lipid ... |
cellular response to growth factor stimulus dTDP biosynthetic process dTTP biosynthetic process dUDP biosynthetic process myoblast differentiation phosphorylation response to cadmium ion response to estrogen thymidine biosynthetic process | cytoplasm; cytosol; mitochondrial matrix; mitochondrion; nucleus | ATP binding nucleoside diphosphate kinase activity thymidylate kinase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Disease variant Intellectual disability Kinase Neurodegeneration Nucleotide biosynthesis Nucleotide-binding Reference proteome Transferase | MAARRGALIV | MAARRGALIVLEGVDRAGKSTQSRKLVEALCAAGHRAELLRFPERSTEIGKLLSSYLQKKSDVEDHSVHLLFSANRWEQVPLIKEKLSQGVTLVVDRYAFSGVAFTGAKENFSLDWCKQPDVGLPKPDLVLFLQLQLADAAKRGAFGHERYENGAFQERALRCFHQLMKDTTLNWKMVDASKSIEAVHEDIRVLSEDAIRTATEKPLGELWK | cellular response to growth factor stimulus dTDP biosynthetic process dTTP biosynthetic process dUDP biosynthetic process myoblast differentiation phosphorylation response to cadmium ion response to estrogen thymidine biosynthetic process cytoplasm; cytosol; mitochondrial matrix; mitochondrion; nucleus ATP binding nucl... |
2'-deoxyribonucleotide biosynthetic process cell proliferation in forebrain deoxyribonucleotide biosynthetic process DNA repair DNA synthesis involved in DNA repair male gonad development mitochondrial DNA replication positive regulation of G0 to G1 transition positive regulation of G1/S transition of mitotic cell cycl... | cell projection; cytosol; mitochondrion; neuronal cell body; nuclear envelope; ribonucleoside-diphosphate reductase complex | ATP binding disordered domain specific binding identical protein binding ribonucleoside-diphosphate reductase activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Homo sapiens | 3D-structure Acetylation Allosteric enzyme ATP-binding Cytoplasm Deoxyribonucleotide synthesis Disulfide bond Nucleotide-binding Oxidoreductase Phosphoprotein Reference proteome | MHVIKRDGRQ | MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGK... | 2'-deoxyribonucleotide biosynthetic process cell proliferation in forebrain deoxyribonucleotide biosynthetic process DNA repair DNA synthesis involved in DNA repair male gonad development mitochondrial DNA replication positive regulation of G0 to G1 transition positive regulation of G1/S transition of mitotic cell cycl... |
apoptotic process involved in morphogenesis camera-type eye development cellular response to gamma radiation lens development in camera-type eye microtubule polymerization or depolymerization muscle organ development negative regulation of amyloid fibril formation negative regulation of apoptotic process negative regul... | actin filament bundle; axon; cardiac myofibril; cell surface; contractile fiber; cytoplasm; cytosol; dendritic spine; extracellular region; I band; lysosome; M band; mitochondrion; myelin sheath; nucleus; perikaryon; plasma membrane; protein-containing complex; synaptic membrane; Z disc | amyloid-beta binding cytoskeletal protein binding identical protein binding metal ion binding microtubule binding protein homodimerization activity protein-containing complex binding structural constituent of eye lens structural molecule activity unfolded protein binding | Mus musculus | Acetylation Chaperone Cytoplasm Direct protein sequencing Eye lens protein Lysosome Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Secreted Zinc | MDIAIHHPWI | MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITREEKPAVAAAPKK | apoptotic process involved in morphogenesis camera-type eye development cellular response to gamma radiation lens development in camera-type eye microtubule polymerization or depolymerization muscle organ development negative regulation of amyloid fibril formation negative regulation of apoptotic process negative regul... |
apoptotic process involved in morphogenesis camera-type eye development cellular response to gamma radiation lens development in camera-type eye microtubule polymerization or depolymerization muscle organ development negative regulation of amyloid fibril formation negative regulation of apoptotic process negative regul... | actin filament bundle; axon; cardiac myofibril; cell surface; contractile fiber; cytoplasm; cytosol; dendritic spine; extracellular region; I band; lysosome; M band; mitochondrion; nucleus; perikaryon; plasma membrane; protein-containing complex; synaptic membrane; Z disc | amyloid-beta binding cytoskeletal protein binding identical protein binding metal ion binding microtubule binding protein homodimerization activity protein-containing complex binding structural constituent of eye lens structural molecule activity unfolded protein binding | Rattus norvegicus | Acetylation Chaperone Cytoplasm Direct protein sequencing Eye lens protein Glycoprotein Lysosome Metal-binding Methylation Nucleus Phosphoprotein Reference proteome Secreted Zinc | MDIAIHHPWI | MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFSTATSLSPFYLRPPSFLRAPSWIDTGLSEMRMEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQASGPERTIPITREEKPAVTAAPKK | apoptotic process involved in morphogenesis camera-type eye development cellular response to gamma radiation lens development in camera-type eye microtubule polymerization or depolymerization muscle organ development negative regulation of amyloid fibril formation negative regulation of apoptotic process negative regul... |
lipoprotein biosynthetic process | outer membrane-bounded periplasmic space; plasma membrane | N-acyltransferase activity | Escherichia coli | 3D-structure Acyltransferase Cell inner membrane Cell membrane Membrane Reference proteome Transferase Transmembrane Transmembrane helix | MAFASLIERQ | MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGLQALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLSLYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPLKGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQPEKTIQVSMVQGDIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEINQQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLG... | lipoprotein biosynthetic process outer membrane-bounded periplasmic space; plasma membrane N-acyltransferase activity Escherichia coli 3D-structure Acyltransferase Cell inner membrane Cell membrane Membrane Reference proteome Transferase Transmembrane Transmembrane helix MAFASLIERQ MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAA... |
cell adhesion detection of light stimulus involved in visual perception photoreceptor cell outer segment organization protein heterooligomerization protein homooligomerization protein localization to plasma membrane protein maturation response to low light intensity stimulus retina development in camera-type eye visual... | membrane; photoreceptor inner segment; photoreceptor outer segment | protein homodimerization activity | Homo sapiens | 3D-structure Cell adhesion Cell projection Cone-rod dystrophy Disease variant Disulfide bond Glycoprotein Membrane Reference proteome Retinitis pigmentosa Sensory transduction Transmembrane Transmembrane helix Vision | MALLKVKFDQ | MALLKVKFDQKKRVKLAQGLWLMNWFSVLAGIIIFSLGLFLKIELRKRSDVMNNSESHFVPNSLIGMGVLSCVFNSLAGKICYDALDPAKYARWKPWLKPYLAICVLFNIILFLVALCCFLLRGSLENTLGQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYDHQTEELNLWVRGCRAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPEESESESQGWLLERSVPETWKAFL... | cell adhesion detection of light stimulus involved in visual perception photoreceptor cell outer segment organization protein heterooligomerization protein homooligomerization protein localization to plasma membrane protein maturation response to low light intensity stimulus retina development in camera-type eye visual... |
angiogenesis artery smooth muscle contraction axon extension cell tip growth cytokine-mediated signaling pathway endothelial cell migration energy homeostasis intracellular calcium ion homeostasis lung alveolus development macrophage activation macrophage chemotaxis negative regulation of hormone secretion neuron proje... | extracellular space | endothelin B receptor binding hormone activity | Rattus norvegicus | Cleavage on pair of basic residues Disulfide bond Reference proteome Secreted Signal Vasoactive Vasoconstrictor | MVSPAWCSIA | MVSPAWCSIALALLLALHEGKGQAAATMEQPASAPKGRGPHLRFRRCSCNSWLDKECVYFCHLDIIWVNTAGQTAPYGLGNPPQRRRRSLPKRCECSSAGDSACATFCHRRPWPEAEVTSSSQGPAAVLETSKTWTAAGDLLQKLRDISAAKLQFVRLRPELTREAIPAHSRRRKR | angiogenesis artery smooth muscle contraction axon extension cell tip growth cytokine-mediated signaling pathway endothelial cell migration energy homeostasis intracellular calcium ion homeostasis lung alveolus development macrophage activation macrophage chemotaxis negative regulation of hormone secretion neuron proje... |
adenylate cyclase-activating adrenergic receptor signaling pathway cell-cell signaling negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure neuron-glial cell signaling norepinephrine-epinephrine vasoconstriction involved in regulation of s... | plasma membrane | alpha1-adrenergic receptor activity identical protein binding | Rattus norvegicus | Cell membrane G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MTFRDILSVT | MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDNQSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCRGAATSAKGYPGTQSSKG... | adenylate cyclase-activating adrenergic receptor signaling pathway cell-cell signaling negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure neuron-glial cell signaling norepinephrine-epinephrine vasoconstriction involved in regulation of s... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to follicle-stimulating hormone stimulus female gamete generation female gonad development follicle-stimulating hormone signaling pathway G protein-coupled receptor signaling pathway gonad development hormone-mediated signaling ... | membrane; plasma membrane; receptor complex | follicle-stimulating hormone receptor activity G protein-coupled peptide receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Leucine-rich repeat Membrane Receptor Reference proteome Repeat Signal Sulfation Transducer Transmembrane Transmembrane helix | MALLLVSLLA | MALLLVSLLAFLSLGSGCHHRICHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIHSLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGASGPVILDISRTRIHSLPSYGLENLKKLRARSTYNLKKLPTLEKLVALMEASLTYPSHCCAFANWRRQISELHPICNKSILRQEVDYMTQARGQRSSLAEDNES... | adenylate cyclase-activating G protein-coupled receptor signaling pathway cellular response to follicle-stimulating hormone stimulus female gamete generation female gonad development follicle-stimulating hormone signaling pathway G protein-coupled receptor signaling pathway gonad development hormone-mediated signaling ... |
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