Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cellular response to leukemia inhibitory factor cysteine biosynthetic process cysteine biosynthetic process via cystathionine cysteine metabolic process endoplasmic reticulum unfolded protein response hydrogen sulfide biosynthetic process lipid metabolic process negative regulation of apoptotic signaling pathway positi... | cytoplasm; cytosol; extracellular exosome | calmodulin binding cystathionine gamma-lyase activity homocysteine desulfhydrase activity identical protein binding L-cysteine desulfhydrase activity L-cystine L-cysteine-lyase (deaminating) pyridoxal phosphate binding selenocystathionine gamma-lyase activity | Homo sapiens | 3D-structure Alternative splicing Amino-acid biosynthesis Calmodulin-binding Cysteine biosynthesis Cytoplasm Disease variant Lipid metabolism Lyase Pyridoxal phosphate Reference proteome | MQEKDASSQG | MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKG... | cellular response to leukemia inhibitory factor cysteine biosynthetic process cysteine biosynthetic process via cystathionine cysteine metabolic process endoplasmic reticulum unfolded protein response hydrogen sulfide biosynthetic process lipid metabolic process negative regulation of apoptotic signaling pathway positi... |
cytoplasm to vacuole transport by the Cvt pathway endocytosis macroautophagy piecemeal microautophagy of the nucleus protein localization to vacuole protein transport regulation of protein-containing complex assembly regulation of vacuole fusion, non-autophagic retrograde transport, endosome to Golgi vacuole inheritanc... | cytosol; fungal-type vacuole; fungal-type vacuole membrane; late endosome; mitochondrial outer membrane; mitochondrion; phagocytic vesicle; vacuole; vacuole-mitochondrion membrane contact site | GTP binding GTPase activity protein-containing complex binding | Saccharomyces cerevisiae | 3D-structure Endosome GTP-binding Isopeptide bond Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Protein transport Reference proteome Transport Ubl conjugation Vacuole | MSSRKKNILK | MSSRKKNILKVIILGDSGVGKTSLMHRYVNDKYSQQYKATIGADFLTKEVTVDGDKVATMQVWDTAGQERFQSLGVAFYRGADCCVLVYDVTNASSFENIKSWRDEFLVHANVNSPETFPFVILGNKIDAEESKKIVSEKSAQELAKSLGDIPLFLTSAKNAINVDTAFEEIARSALQQNQADTEAFEDDYNDAINIRLDGENNSCSC | cytoplasm to vacuole transport by the Cvt pathway endocytosis macroautophagy piecemeal microautophagy of the nucleus protein localization to vacuole protein transport regulation of protein-containing complex assembly regulation of vacuole fusion, non-autophagic retrograde transport, endosome to Golgi vacuole inheritanc... |
cell adhesion cell-cell adhesion phagocytosis | extracellular exosome; plasma membrane | integrin binding signaling receptor binding | Homo sapiens | 3D-structure Cell adhesion Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phagocytosis Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MATMVPSVLW | MATMVPSVLWPRACWTLLVCCLLTPGVQGQEFLLRVEPQNPVLSAGGSLFVNCSTDCPSSEKIALETSLSKELVASGMGWAAFNLSNVTGNSRILCSVYCNGSQITGSSNITVYRLPERVELAPLPPWQPVGQNFTLRCQVEDGSPRTSLTVVLLRWEEELSRQPAVEEPAEVTATVLASRDDHGAPFSCRTELDMQPQGLGLFVNTSAPRQLRTFVLPVTPPRLVAPRFLEVETSWPVDCTLDGLFPASEAQVYLALGDQMLNATVMNHGDTLTATATATARADQEGAREIVCNVTLGGERREARENLTVFSFLGPIVN... | cell adhesion cell-cell adhesion phagocytosis extracellular exosome; plasma membrane integrin binding signaling receptor binding Homo sapiens 3D-structure Cell adhesion Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Membrane Phagocytosis Phosphoprotein Reference proteome Repeat Signal Trans... |
cell division G1/S transition of mitotic cell cycle mitotic cell cycle phase transition positive regulation of DNA replication premeiotic DNA replication regulation of DNA-templated transcription regulation of protein localization regulation of protein phosphorylation | cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus; spindle pole body | cyclin-dependent protein serine/threonine kinase regulator activity | Saccharomyces cerevisiae | Cell cycle Cell division Cyclin Reference proteome | MNCIPSPISE | MNCIPSPISERKIQINNEDCIGKENAFHTIPRESSINLTPHSTNEKKVLSEVNSNKIDSLQLPRGKLQRDSTHLEKTRKRQLSNDSTDPIEPKTVKKIKCHQWKNLDSIEMDDPFMVAEYTDSIFSHLYEKEIQMLPTHNYLMDTQSPYHLKSSMRALLIDWLVEVHEKFHCLPETLFLAINLLDRFLSQNVVKLNKLQLLCITCLFIACKFEEVKLPKITNFAYVTDGAATVEGIRKAELFVLSSLGYNISLPNPLNFIRRISKADNYCIETRNMAKFIMEYSICCNKFIHLKPSYLAAMSMYIARKIKNENSKWDETF... | cell division G1/S transition of mitotic cell cycle mitotic cell cycle phase transition positive regulation of DNA replication premeiotic DNA replication regulation of DNA-templated transcription regulation of protein localization regulation of protein phosphorylation cyclin-dependent protein kinase holoenzyme complex;... |
cell division G2/M transition of mitotic cell cycle meiotic cell cycle mitotic morphogenesis checkpoint signaling negative regulation of G2/MI transition of meiotic cell cycle negative regulation of mitotic spindle pole body separation phosphorylation positive regulation of sphingolipid biosynthetic process re-entry in... | cellular bud neck; cytoplasm; nucleus | ATP binding metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity | Saccharomyces cerevisiae | ATP-binding Cell cycle Cell division Isopeptide bond Kinase Magnesium Meiosis Metal-binding Mitosis Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase Ubl conjugation | MSSLDEDEED | MSSLDEDEEDFEMLDTENLQFMGKKMFGKQAGEDESDDFAIGGSTPTNKLKFYPYSNNKLTRSTGTLNLSLSNTALSEANSKFLGKIEEEEEEEEEGKDEESVDSRIKRWSPFHENESVTTPITKRSAEKTNSPISLKQWNQRWFPKNDARTENTSSSSSYSVAKPNQSAFTSSGLVSKMSMDTSLYPAKLRIPETPVKKSPLVEGRDHKHVHLSSSKNASSSLSVSPLNFVEDNNLQEDLLFSDSPSSKALPSIHVPTIDSSPLSEAKYHAHDRHNNQTNILSPTNSLVTNSSPQTLHSNKFKKIKRARNSVILKNREL... | cell division G2/M transition of mitotic cell cycle meiotic cell cycle mitotic morphogenesis checkpoint signaling negative regulation of G2/MI transition of meiotic cell cycle negative regulation of mitotic spindle pole body separation phosphorylation positive regulation of sphingolipid biosynthetic process re-entry in... |
mandelate catabolic process | mitochondrial intermembrane space; respirasome | (S)-mandelate dehydrogenase activity heme binding metal ion binding | Rhodotorula graminis | Aromatic hydrocarbons catabolism Direct protein sequencing Electron transport Flavoprotein FMN Heme Iron Mandelate pathway Metal-binding Mitochondrion Oxidoreductase Respiratory chain Transit peptide Transport | MSFARVRTAL | MSFARVRTALRCQRAAASPAPPKVQARRFANKAAPHASASSAGSRAFHLGLAAGAALAVGGAGLYLFSRSPVLLDAQLPVKQRGRARSISAAEVAKHNSRDSMWVCIDDEVWDITNFVELHPGGAKVLEQNAGKDVTKVFKSIHPPKTLEKFLTDDNFVGRIDVDEVTKIGGGKNAEDLRIEQARKELRNVETVVCLDEFEEISQKILSEMAMAYYGTGAETEQTLRDEREAWQRVRFRPRVLRKMRHIDTNTTFLGIPTPLPIFVAPAGLARLGHPDGEQNIVRGVAKHDILQVVSSGASCSIDEIFEVKEPDQNLAWQ... | mandelate catabolic process mitochondrial intermembrane space; respirasome (S)-mandelate dehydrogenase activity heme binding metal ion binding Rhodotorula graminis Aromatic hydrocarbons catabolism Direct protein sequencing Electron transport Flavoprotein FMN Heme Iron Mandelate pathway Metal-binding Mitochondrion Oxido... |
camera-type eye photoreceptor cell differentiation cell adhesion detection of light stimulus involved in visual perception photoreceptor cell outer segment organization protein heterooligomerization protein homooligomerization protein localization to photoreceptor outer segment regulation of gene expression retina deve... | photoreceptor outer segment; photoreceptor outer segment membrane | protein homodimerization activity | Mus musculus | Cell adhesion Cell projection Disulfide bond Membrane Reference proteome Sensory transduction Transmembrane Transmembrane helix Vision | MAPVLPVVLP | MAPVLPVVLPLQPRIRLAQGIWLLSWLLALVGGLTLLCSGHLLVQLGHLGTFLAPSCSFPALPQTALAAGTVALGTGLGGAGASRASLDAAQYPPWRGVLTPLLAVGTAAGGGLLTLALGLALALPVSLNQGLEEGLEAALAHYKDTEVPGRCQAKRLMDELQLRYHCCGRHGYKDWFGVQWVSNRYLDPSDQDVVDRIQSNVEGLYLIDGVPFSCCNPHSPRPCLQSQLSDPYAHPLFDPRQPNLNLWAQGCHEVLLEHLQGLSGTLGSILAVTLLLQILVLLGLRYLQTALEGLGGVIDGEGEAQGYLFPGGLKDILK... | camera-type eye photoreceptor cell differentiation cell adhesion detection of light stimulus involved in visual perception photoreceptor cell outer segment organization protein heterooligomerization protein homooligomerization protein localization to photoreceptor outer segment regulation of gene expression retina deve... |
indoleacetic acid biosynthetic process | apoplast; chloroplast; cytosol; plasmodesma | indole-3-acetonitrile nitrilase activity indole-3-acetonitrile nitrile hydratase activity nitrilase activity | Arabidopsis thaliana | Acetylation Alternative splicing Hydrolase Reference proteome | MSSTKDMSTV | MSSTKDMSTVQNATPFNGVAPSTTVRVTIVQSSTVYNDTPATIDKAEKYIVEAASKGAELVLFPEGFIGGYPRGFRFGLAVGVHNEEGRDEFRKYHASAIHVPGPEVARLADVARKNHVYLVMGAIEKEGYTLYCTVLFFSPQGQFLGKHRKLMPTSLERCIWGQGDGSTIPVYDTPIGKLGAAICWENRMPLYRTALYAKGIELYCAPTADGSKEWQSSMLHIAIEGGCFVLSACQFCQRKHFPDHPDYLFTDWYDDKEHDSIVSQGGSVIISPLGQVLAGPNFESEGLVTADIDLGDIARAKLYFDSVGHYSRPDVLH... | indoleacetic acid biosynthetic process apoplast; chloroplast; cytosol; plasmodesma indole-3-acetonitrile nitrilase activity indole-3-acetonitrile nitrile hydratase activity nitrilase activity Arabidopsis thaliana Acetylation Alternative splicing Hydrolase Reference proteome MSSTKDMSTV MSSTKDMSTVQNATPFNGVAPSTTVRVTIVQSST... |
cytoplasmic translation translation | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; focal adhesion; membrane; nucleus; ribosome | RNA binding rRNA binding structural constituent of ribosome | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein | MKTILSNQTV | MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQADE | cytoplasmic translation translation cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; focal adhesion; membrane; nucleus; ribosome RNA binding rRNA binding structural constituent of ribosome Homo sapiens 3D-structure Acetylation Cytoplasm Direct protein sequencing Reference proteome Ribonucleopr... |
B cell mediated immunity B cell proliferation cell-cell signaling extrinsic apoptotic signaling pathway positive regulation of T cell proliferation signal transduction T cell mediated immunity tumor necrosis factor-mediated signaling pathway | extracellular exosome; plasma membrane | cytokine activity protease binding signaling receptor binding tumor necrosis factor receptor binding | Homo sapiens | 3D-structure Alternative splicing Cytokine Disease variant Disulfide bond Glycoprotein Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix | MPEEGSGCSV | MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRP | B cell mediated immunity B cell proliferation cell-cell signaling extrinsic apoptotic signaling pathway positive regulation of T cell proliferation signal transduction T cell mediated immunity tumor necrosis factor-mediated signaling pathway extracellular exosome; plasma membrane cytokine activity protease binding sign... |
CD8-positive, alpha-beta T cell differentiation cell-cell signaling defense response to Gram-positive bacterium immune response positive regulation of transcription by RNA polymerase II regulation of T cell proliferation | extracellular space; plasma membrane | cytokine activity signaling receptor binding tumor necrosis factor receptor binding | Homo sapiens | Cytokine Disulfide bond Glycoprotein Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix | MDPGLQQALN | MDPGLQQALNGMAPPGDTAMHVPAGSVASHLGTTSRSYFYLTTATLALCLVFTVATIMVLVVQRTDSIPNSPDNVPLKGGNCSEDLLCILKRAPFKKSWAYLQVAKHLNKTKLSWNKDGILHGVRYQDGNLVIQFPGLYFIICQLQFLVQCPNNSVDLKLELLINKHIKKQALVTVCESGMQTKHVYQNLSQFLLDYLQVNTTISVNVDTFQYIDTSTFPLENVLSIFLYSNSD | CD8-positive, alpha-beta T cell differentiation cell-cell signaling defense response to Gram-positive bacterium immune response positive regulation of transcription by RNA polymerase II regulation of T cell proliferation extracellular space; plasma membrane cytokine activity signaling receptor binding tumor necrosis fa... |
cell wall organization peptidoglycan biosynthetic process peptidoglycan metabolic process proteolysis regulation of cell shape | plasma membrane | beta-lactamase activity carboxypeptidase activity penicillin binding serine-type D-Ala-D-Ala carboxypeptidase activity | Escherichia coli | 3D-structure Carboxypeptidase Cell inner membrane Cell membrane Cell shape Cell wall biogenesis/degradation Hydrolase Membrane Peptidoglycan synthesis Protease Reference proteome Signal | MKRRLIIAAS | MKRRLIIAASLFVFNLSSGFAAENIPFSPQPPEIHAGSWVLMDYTTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVFVGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLHLKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRNGLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGADSAKGREEEARKLLRWGQQNFTTVQILHRGKKVGTERIWYGDKENIDLGTEQEFWMVLP... | cell wall organization peptidoglycan biosynthetic process peptidoglycan metabolic process proteolysis regulation of cell shape plasma membrane beta-lactamase activity carboxypeptidase activity penicillin binding serine-type D-Ala-D-Ala carboxypeptidase activity Escherichia coli 3D-structure Carboxypeptidase Cell inner ... |
sulfate transport thiosulfate transport | plasma membrane | thiosulfate transmembrane transporter activity | Escherichia coli | Cell inner membrane Cell membrane Membrane Reference proteome Sulfate transport Transmembrane Transmembrane helix Transport | MFSMILSGLI | MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIVKNNRMFYALLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIGGYIFGLGIVLAGGCATGTWYRAGEGLIGSWIALFTYMVMSAVMRSPHASGLNQTLQHYSTEHNSIAETFNLSVWPLVAVLLVITLWVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLSEATGRMFGLGITSPTANILQFLVAGDMKYINWGVFLVLGIFVGSFIAAKASREFRVRAADAQTTLRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWI... | sulfate transport thiosulfate transport plasma membrane thiosulfate transmembrane transporter activity Escherichia coli Cell inner membrane Cell membrane Membrane Reference proteome Sulfate transport Transmembrane Transmembrane helix Transport MFSMILSGLI MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIVKNNRMFYALLIAISVQSVGVFALIQAGLL... |
formaldehyde catabolic process protein homotetramerization | cytosol; protein-containing complex | carboxylic ester hydrolase activity hydroxyacylglutathione hydrolase activity identical protein binding S-formylglutathione hydrolase activity | Escherichia coli | Hydrolase Reference proteome Serine esterase | MEMLEEHRCF | MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPPVLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEKVANDDGYDLGQGAGFYLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPGKYTSVSAFAPIVNPCSVPWGIKAFSSYLGEDKNAWLEWDSCALMYASNAQDAIPTLIDQGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYLLK | formaldehyde catabolic process protein homotetramerization cytosol; protein-containing complex carboxylic ester hydrolase activity hydroxyacylglutathione hydrolase activity identical protein binding S-formylglutathione hydrolase activity Escherichia coli Hydrolase Reference proteome Serine esterase MEMLEEHRCF MEMLEEHRC... |
protein homotetramerization purine nucleoside catabolic process pyrimidine nucleobase metabolic process pyrimidine ribonucleoside catabolic process | cytosol; protein-containing complex | calcium ion binding identical protein binding purine nucleosidase activity uridine nucleosidase activity | Escherichia coli | 3D-structure Calcium Glycosidase Hydrolase Metal-binding Reference proteome | MEKRKIILDC | MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH | protein homotetramerization purine nucleoside catabolic process pyrimidine nucleobase metabolic process pyrimidine ribonucleoside catabolic process cytosol; protein-containing complex calcium ion binding identical protein binding purine nucleosidase activity uridine nucleosidase activity Escherichia coli 3D-structure C... |
nucleobase catabolic process | protein-containing complex | hydrolase activity, acting on glycosyl bonds identical protein binding manganese ion binding pseudouridylate synthase activity | Escherichia coli | 3D-structure Glycosidase Hydrolase Lyase Manganese Metal-binding Reference proteome | MSELKISPEL | MSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPFPQNAQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFVVAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTVVCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSASEIARAMVVKWQSGLNGGLVVANPIPEQFAMPEHTINAAIDQAVAEAEAQGVIGKESTPFLLARVAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLAG | nucleobase catabolic process protein-containing complex hydrolase activity, acting on glycosyl bonds identical protein binding manganese ion binding pseudouridylate synthase activity Escherichia coli 3D-structure Glycosidase Hydrolase Lyase Manganese Metal-binding Reference proteome MSELKISPEL MSELKISPELLQISPEVQDALKNKK... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of metabolic process | cytoplasm; plasma membrane | hormone binding melanocortin receptor activity | Homo sapiens | 3D-structure Cell membrane G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNSSFHLHFL | MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACS... | adenylate cyclase-activating G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of metabolic process cytoplasm; plasma membrane hormone binding melanocortin receptor activity Homo sapiens 3D-structure Cell membrane G-protei... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway circadian regulation of gene expression homoiothermy locomotor rhythm regulation of blood pressure regulation of feeding behavior regulation of heart rate regulation of met... | cytoplasm; plasma membrane | melanocortin receptor activity melanocyte-stimulating hormone receptor activity neuropeptide binding peptide hormone binding | Mus musculus | Biological rhythms Cell membrane G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNSSCCLSSV | MNSSCCLSSVSPMLPNLSEHPAAPPASNRSGSGFCEQVFIKPEVFLALGIVSLMENILVILAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIAVINSDSLTLEDQFIQHMDNIFDSMICISLVASICNLLAIAIDRYVTIFYALRYHSIMTVRKALTLIGVIWVCCGICGVMFIIYSESKMVIVCLITMFFAMVLLMGTLYIHMFLFARLHVQRIAVLPPAGVVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFKEILCGCNSM... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway circadian regulation of gene expression homoiothermy locomotor rhythm regulation of blood pressure regulation of feeding behavior regulation of heart rate regulation of met... |
cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape UDP-N-acetylgalactosamine biosynthetic process | cytoplasm | UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity | Enterobacter cloacae subsp. cloacae | 3D-structure Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Cytoplasm Direct protein sequencing Peptidoglycan synthesis Pyruvate Transferase | MDKFRVQGPT | MDKFRVQGPTRLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDIDTTMKLLTQLGTKVERNGSVWIDASNVNNFSAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHIFGLEKLGAEIKLEEGYVKASVNGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTIIENAAREPEIVDTANFLVALGAKISGQGTDRITIEGVERLGGGVYRVLPDRIETGTFLVAAAISGGKIVCRNAQPDTLDAVLAKLREAGADIETGEDWISLDMHGKRPKAVTVRTAPHPAFPTDMQAQFTLLNLVAEGT... | cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape UDP-N-acetylgalactosamine biosynthetic process cytoplasm UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity Enterobacter cloacae subsp. cloacae 3D-structure Cell cycle Cell division Cell shape Cell wall b... |
blood vessel morphogenesis collagen fibril organization peptidyl-lysine oxidation | collagen-containing extracellular matrix; extracellular region; extracellular space | collagen binding copper ion binding protein-lysine 6-oxidase activity | Bos taurus | Copper Direct protein sequencing Disulfide bond Glycoprotein LTQ Metal-binding Oxidoreductase Reference proteome Secreted Signal Sulfation TPQ | MRFAWTALLG | MRFAWTALLGSLQLCALVRCAPPAASHRQPPREQAAAPGAWRQKIQWENNGQVFSLLSLGSQYQPQRRRDPGATAPGAANATAPQMRTPILLLRNNRTAAARVRTAGPSAAAAGRPRPAARHWFQAGYSTSGAHDAGTSRADNQTAPGEVPTLSNLRPPNRVEVDGMVGDDPYNPYKYTDDNPYYNYYDTYERPRPGSRYRPGYGTGYFQYGLPDLVPDPYYIQASTYVQKMAMYNLRCAAEENCLASSAYRXDVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDASTQRRVAEGH... | blood vessel morphogenesis collagen fibril organization peptidyl-lysine oxidation collagen-containing extracellular matrix; extracellular region; extracellular space collagen binding copper ion binding protein-lysine 6-oxidase activity Bos taurus Copper Direct protein sequencing Disulfide bond Glycoprotein LTQ Metal-bi... |
ADP biosynthetic process AMP metabolic process ATP metabolic process phosphorylation | cytoplasm; cytosol; mitochondrial intermembrane space; mitochondrion; nucleus | adenylate kinase activity ATP binding | Schizosaccharomyces pombe | ATP-binding Cytoplasm Kinase Mitochondrion Nucleotide-binding Nucleus Reference proteome Transferase | MAGMRLILVG | MAGMRLILVGPPGAGKGTQAPNIQKKYGIAHLATGDMLRSQVARQTELGKEAKKIMDQGGLVSDDIVTGMIKDEILNNPECKNGFILDGFPRTVVQAEKLTALLDELKLDLNTVLELQVDDELLVRRITGRLVHPGSGRSYHLEFNPPKVPMKDDVTGEPLIQRSDDNADALRKRLVTYHEQTTPVVEFYKKKGKWAAVDAAQKPEQVWEQIVAILEKAE | ADP biosynthetic process AMP metabolic process ATP metabolic process phosphorylation cytoplasm; cytosol; mitochondrial intermembrane space; mitochondrion; nucleus adenylate kinase activity ATP binding Schizosaccharomyces pombe ATP-binding Cytoplasm Kinase Mitochondrion Nucleotide-binding Nucleus Reference proteome Tra... |
auxin-activated signaling pathway response to auxin | nucleus | DNA binding DNA-binding transcription factor activity identical protein binding transcription cis-regulatory region binding | Arabidopsis thaliana | Auxin signaling pathway Nucleus Reference proteome Repressor Transcription Transcription regulation | MEKVDVYDEL | MEKVDVYDELVNLKATELRLGLPGTEETVSCGKSNKRVLPEATEKEIESTGKTETASPPKAQIVGWPPVRSYRKNNVQTKKSESEGQGNYVKVSMDGAPYLRKIDLTMYKQYPELMKSLENMFKFSVGEYFEREGYKGSDFVPTYEDKDGDWMLVGDVPWEMFVSSCKRLRIMKGSEVKGLGCGGL | auxin-activated signaling pathway response to auxin nucleus DNA binding DNA-binding transcription factor activity identical protein binding transcription cis-regulatory region binding Arabidopsis thaliana Auxin signaling pathway Nucleus Reference proteome Repressor Transcription Transcription regulation MEKVDVYDEL MEKV... |
auxin-activated signaling pathway response to auxin | nucleus | DNA-binding transcription factor activity | Arabidopsis thaliana | Auxin signaling pathway Nucleus Reference proteome Repressor Transcription Transcription regulation | MANESNNLGL | MANESNNLGLEITELRLGLPGDIVVSGESISGKKRASPEVEIDLKCEPAKKSQVVGWPPVCSYRRKNSLERTKSSYVKVSVDGAAFLRKIDLEMYKCYQDLASALQILFGCYINFDDTLKESECVPIYEDKDGDWMLAGDVPWEMFLGSCKRLRIMKRSCNRG | auxin-activated signaling pathway response to auxin nucleus DNA-binding transcription factor activity Arabidopsis thaliana Auxin signaling pathway Nucleus Reference proteome Repressor Transcription Transcription regulation MANESNNLGL MANESNNLGLEITELRLGLPGDIVVSGESISGKKRASPEVEIDLKCEPAKKSQVVGWPPVCSYRRKNSLERTKSSYVKVSVDGAAF... |
cell communication by electrical coupling gap junction assembly intercellular transport jump response monoatomic ion transmembrane transport phototransduction regulation of membrane depolarization response to light stimulus transmembrane transport | gap junction; plasma membrane | gap junction channel activity photoreceptor activity | Drosophila melanogaster | Alternative splicing Behavior Cell junction Cell membrane Gap junction Ion channel Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport | MLDIFRGLKN | MLDIFRGLKNLVKVSHVKTDSIVFRLHYSITVMILMSFSLIITTRQYVGNPIDCVHTKDIPEDVLNTYCWIQSTYTLKSLFLKKQGVSVPYPGIGNSDGDPADKKHYKYYQWVCFCLFFQAILFYTPRWLWKSWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENLRYHNWWAYRYYVCELLALINVIGQMFLMNRFFDGEFITFGLKVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHDAICILPLNVVNEKIYIFLWFWFILLTFLTLLTLIYRVVIIFSPRMRVYLFRMRFRLVRRDAIEIIV... | cell communication by electrical coupling gap junction assembly intercellular transport jump response monoatomic ion transmembrane transport phototransduction regulation of membrane depolarization response to light stimulus transmembrane transport gap junction; plasma membrane gap junction channel activity photorecepto... |
aspartate biosynthetic process aspartate catabolic process cellular response to insulin stimulus fatty acid homeostasis gluconeogenesis glutamate catabolic process to 2-oxoglutarate glutamate catabolic process to aspartate glycerol biosynthetic process Notch signaling pathway oxaloacetate metabolic process response to ... | cytosol | L-aspartate:2-oxoglutarate aminotransferase activity L-cysteine transaminase activity phosphatidylserine decarboxylase activity pyridoxal phosphate binding | Bos taurus | Amino-acid biosynthesis Aminotransferase Cytoplasm Pyridoxal phosphate Reference proteome Transferase | MAPPSIFAEV | MAPPSIFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDSQPWVLPVVRKVEQRIANDSSINHEYLPILGLAEFRTCASRLALGDDSPALQEKRVGGVQCLGGTGALRIGAEFLARWYNGTNNKDTPVYVSSPTWENHNGVFIAAGFKDIRSYHYWDAAKRGLDLQGFLNDLEKAPEFSIFVLHACAHNPTGTDPTPEQWKQIASVMKRRFLFPFFDSAYQGFASGSLEKDAWAIRYFVSEGFELFCAQSFSKNFGLYNERVGNLTVVAKEPDSILRVLSQMEKIVRITWSNPPAQGARIVARTLSDPELFNEW... | aspartate biosynthetic process aspartate catabolic process cellular response to insulin stimulus fatty acid homeostasis gluconeogenesis glutamate catabolic process to 2-oxoglutarate glutamate catabolic process to aspartate glycerol biosynthetic process Notch signaling pathway oxaloacetate metabolic process response to ... |
adiponectin-activated signaling pathway fatty acid transport lipid biosynthetic process long-chain fatty acid import into cell long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process positive regulation of cold-induced thermogenesis positive regulation of long-chain fatty acid import acro... | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion; peroxisomal membrane | arachidonate-CoA ligase activity ATP binding long-chain fatty acid-CoA ligase activity oleoyl-CoA ligase activity phytanate-CoA ligase activity pristanate-CoA ligase activity protein serine/threonine kinase activator activity | Homo sapiens | Acetylation Alternative splicing ATP-binding Direct protein sequencing Endoplasmic reticulum Fatty acid metabolism Glycoprotein Ligase Lipid metabolism Magnesium Membrane Microsome Mitochondrion Mitochondrion outer membrane Nitration Nucleotide-binding Peroxisome Phosphoprotein Reference proteome Signal-anchor Transmem... | MQAHELFRYF | MQAHELFRYFRMPELVDFRQYVRTLPTNTLMGFGAFAALTTFWYATRPKPLKPPCDLSMQSVEVAGSGGARRSALLDSDEPLVYFYDDVTTLYEGFQRGIQVSNNGPCLGSRKPDQPYEWLSYKQVAELSECIGSALIQKGFKTAPDQFIGIFAQNRPEWVIIEQGCFAYSMVIVPLYDTLGNEAITYIVNKAELSLVFVDKPEKAKLLLEGVENKLIPGLKIIVVMDAYGSELVERGQRCGVEVTSMKAMEDLGRANRRKPKPPAPEDLAVICFTSGTTGNPKGAMVTHRNIVSDCSAFVKATENTVNPCPDDTLISFL... | adiponectin-activated signaling pathway fatty acid transport lipid biosynthetic process long-chain fatty acid import into cell long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process positive regulation of cold-induced thermogenesis positive regulation of long-chain fatty acid import acro... |
positive regulation of glycolytic process transcription elongation by RNA polymerase II | chromatin; nucleus | DNA-binding transcription factor activity protein dimerization activity sequence-specific DNA binding | Saccharomyces cerevisiae | 3D-structure Activator DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MNSILDRNVR | MNSILDRNVRSSETTLIKPESEFDNWLSDENDGASHINVNKDSSSVLSASSSTWFEPLENIISSASSSSIGSPIEDQFISSNNEESALFPTDQFFSNPSSYSHSPEVSSSIKREEDDNALSLADFEPASLQLMPNMINTDNNDDSTPLKNEIELNDSFIKTNLDAKETKKRAPRKRLTPFQKQAHNKIEKRYRININTKIARLQQIIPWVASEQTAFEVGDSVKKQDEDGAETAATTPLPSAAATSTKLNKSMILEKAVDYILYLQNNERLYEMEVQRLKSEIDTLKQDQK | positive regulation of glycolytic process transcription elongation by RNA polymerase II chromatin; nucleus DNA-binding transcription factor activity protein dimerization activity sequence-specific DNA binding Saccharomyces cerevisiae 3D-structure Activator DNA-binding Nucleus Phosphoprotein Reference proteome Transcri... |
cellular response to insulin stimulus fatty acid transport long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process neuroblast proliferation neuron development phospholipid biosynthetic process positive regulation of long-chain fatty acid import across plasma membrane positive regulation o... | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; peroxisomal membrane | arachidonate-CoA ligase activity ATP binding enzyme binding long-chain fatty acid-CoA ligase activity protein homodimerization activity | Rattus norvegicus | Alternative splicing ATP-binding Endoplasmic reticulum Fatty acid metabolism Ligase Lipid metabolism Magnesium Membrane Microsome Mitochondrion Mitochondrion outer membrane Nucleotide-binding Peroxisome Reference proteome Signal-anchor Transmembrane Transmembrane helix | MQTQEILRIL | MQTQEILRILRLPELSDLGQFFRSLSATTLVSMGALAAILAYWLTHRPKALQPPCNLLMQSEEVEDSGGARRSVIGDCTQLLTHYYDDARTMYQVFRRGLSISGNGPCLGFRKPEQPYQWLSYQEVAKRAEFLGSGLLQHDCKVGTEQFIGVFAQNRPEWIIAELACYTYSMVVVPLYDTLGPGSIRYIINTADICTVIVDKPHKAILLLEHVERKETPGLKLVILMEPFDDALRERGKKCGVDIKSMQAIEDSGQENHRVPVPPRPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHFSYL... | cellular response to insulin stimulus fatty acid transport long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process neuroblast proliferation neuron development phospholipid biosynthetic process positive regulation of long-chain fatty acid import across plasma membrane positive regulation o... |
adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion mediated by cadherin cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules | adherens junction; catenin complex; caveola; Golgi apparatus; neuromuscular junction; plasma membrane | cadherin binding calcium ion binding | Mus musculus | Calcium Cell adhesion Cell membrane Cleavage on pair of basic residues Glycoprotein Membrane Metal-binding Reference proteome Repeat Signal Transmembrane Transmembrane helix | MGSALLLALG | MGSALLLALGLLAQSLGLSWAVPEPKPSTLYPWRRASAPGRVRRAWVIPPISVSENHKRLPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRNVFSIDKFTGRVYLNATLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQDVFRGRILEGAIPGTFVTRAEATDADDPETDNAALRFSILEQGSPEFFSIDEHTGEIRTVQVGLDREVVAVYNLTLQVADMSGDGLTATASAIISIDDINDNAPEFTKDEFFMEAAEAVSGVDVGRLEVEDKDLPGSPNWVARFTILEGDPDGQFKIYTDPKTNEGV... | adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion mediated by cadherin cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules adherens junction; catenin complex; caveola; Golgi appara... |
cell-cell adhesion cell-cell adhesion mediated by cadherin glial cell differentiation homophilic cell adhesion via plasma membrane adhesion molecules neuronal stem cell population maintenance | adherens junction; cell surface; cell-cell junction; desmosome; intercalated disc; plasma membrane; sarcolemma | calcium ion binding | Xenopus laevis | Calcium Cell adhesion Cell junction Cell membrane Cleavage on pair of basic residues Glycoprotein Membrane Metal-binding Reference proteome Repeat Signal Transmembrane Transmembrane helix | MCRKEPFLLP | MCRKEPFLLPTALCILAALVLHQGPVEALGGSRLCKTGFLEDVYHASVYRSVHEGQPLLNVKFTDCGADRRIHYETSNPTDFRIDGDGIVCASRTFDISPEQAEFLVYAQDEDTRELWHVTVKITLRPRHVQDLHQGFHKVREIKFSTQRKHNGLQRQKRDWVIPPINVPENARGTFPQELVGIRSDRDKSLSLRYSVTGPGADQPPLGVFIINPISGQLSVTKPLDREQIATFHLRAHAVDVNGNQVENPIDIVINVIDMNDNRPEFLHQIWNGTIPEGSKPGTYVMTVTAIDGDDPKQPNGMLRYKILSQTPASSSPN... | cell-cell adhesion cell-cell adhesion mediated by cadherin glial cell differentiation homophilic cell adhesion via plasma membrane adhesion molecules neuronal stem cell population maintenance adherens junction; cell surface; cell-cell junction; desmosome; intercalated disc; plasma membrane; sarcolemma calcium ion bindi... |
homophilic cell adhesion via plasma membrane adhesion molecules | plasma membrane | calcium ion binding | Xenopus laevis | 3D-structure Calcium Cell adhesion Cell membrane Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Membrane Metal-binding Reference proteome Repeat Signal Transmembrane Transmembrane helix | MGSTRLRNAS | MGSTRLRNASVWLCGLLCLLQVVPSINADVSGCKPGFSSAEYIFSVNRRELERGRKLGKVNFSDCTTRKHGLYDVGDSRFRVLPDGTVLVKRHVKLHKDTKFTISTWDARGIKHSTNIAVASKRHRSGEEAHSRSSKLPVLTFPETHTGLKRKKRDWVIPPIKVSENERGPFPKRLVQIKSNKDRFNKVYYSITGQGADNPPQGVFRIEWETGWMLVTRPLDREEYDKYVLSSHAVSENGSPVEEPMEITINVIDQNDNRPKFTQDVFRGSVREGVQPGTQVMAVSATDEDDNIDSLNGVLSYSILKQDPEEPIPNLFTI... | homophilic cell adhesion via plasma membrane adhesion molecules plasma membrane calcium ion binding Xenopus laevis 3D-structure Calcium Cell adhesion Cell membrane Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Membrane Metal-binding Reference proteome Repeat Signal Transmembra... |
adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion mediated by cadherin cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules sprouting angiogenesis | adherens junction; catenin complex; cell surface; side of membrane; supramolecular fiber | cadherin binding calcium ion binding | Gallus gallus | 3D-structure Alternative splicing Calcium Cell adhesion Cell membrane Cleavage on pair of basic residues Direct protein sequencing Glycoprotein GPI-anchor Lipoprotein Membrane Metal-binding Reference proteome Repeat Signal | MQHKTQLTLS | MQHKTQLTLSFLLSQVLLLACAEDLECTPGFQQKVFYIEQPFEFTEDQPILNLVFDDCKGNNKLNFEVSNPDFKVEHDGSLVALKNVSEAGRALFVHARSEHAEDMAEILIVGADEKHDALKEIFKIEGNLGIPRQKRAILATPILIPENQRPPFPRSVGKVIRSEGTEGAKFRLSGKGVDQDPKGIFRINEISGDVSVTRPLDREAIANYELEVEVTDLSGKIIDGPVRLDISVIDQNDNRPMFKEGPYVGHVMEGSPTGTTVMRMTAFDADDPSTDNALLRYNILKQTPTKPSPNMFYIDPEKGDIVTVVSPVLLDRE... | adherens junction organization calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules cell morphogenesis cell-cell adhesion mediated by cadherin cell-cell junction assembly homophilic cell adhesion via plasma membrane adhesion molecules sprouting angiogenesis adherens junction; catenin complex... |
carbohydrate metabolic process response to cold systemic acquired resistance | apoplast; cytosol; endoplasmic reticulum; plant-type vacuole; secretory vesicle | cellulase activity glucan endo-1,3-beta-D-glucosidase activity glucan exo-1,3-beta-glucosidase activity | Arabidopsis thaliana | Apoplast Cell wall Direct protein sequencing Endoplasmic reticulum Glycosidase Hydrolase Pathogenesis-related protein Plant defense Reference proteome Secreted Signal | MSESRSLASP | MSESRSLASPPMLMILLSLVIASFFNHTAGQIGVCYGMLGDTLPSPSDVVALYKQQNIQRMRLYGPDPGALAALRGSDIELILDVPSSDLERLASSQTEADKWVQENVQSYRDGVRFRYINVGNEVKPSVGGFLLQAMQNIENAVSGAGLEVKVSTAIATDTTTDTSPPSQGRFRDEYKSFLEPVIGFLASKQSPLLVNLYPYFSYMGDTANIHLDYALFTAQSTVDNDPGYSYQNLFDANLDSVYAALEKSGGGSLEIVVSETGWPTEGAVGTSVENAKTYVNNLIQHVKNGSPRRPGKAIETYIFAMFDENKKEPTYE... | carbohydrate metabolic process response to cold systemic acquired resistance apoplast; cytosol; endoplasmic reticulum; plant-type vacuole; secretory vesicle cellulase activity glucan endo-1,3-beta-D-glucosidase activity glucan exo-1,3-beta-glucosidase activity Arabidopsis thaliana Apoplast Cell wall Direct protein sequ... |
formate catabolic process | cytoplasm | formate dehydrogenase (NAD+) activity NAD binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Pseudomonas sp. | 3D-structure Cytoplasm Direct protein sequencing NAD Oxidoreductase | MAKVLCVLYD | MAKVLCVLYDDPVDGYPKTYARDDLPKIDHYPGGQTLPTPKAIDFTPGQLLGSVSGELGLRKYLESNGHTLVVTSDKDGPDSVFERELVDADVVISQPFWPAYLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRNVTVAEVTYCNSISVAEHVVMMILSLVRNYLPSHEWARKGGWNIADCVSHAYDLEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTDRHRLPESVEKELNLTWHATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAGDVWFPQPAPKDH... | formate catabolic process cytoplasm formate dehydrogenase (NAD+) activity NAD binding oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Pseudomonas sp. 3D-structure Cytoplasm Direct protein sequencing NAD Oxidoreductase MAKVLCVLYD MAKVLCVLYDDPVDGYPKTYARDDLPKIDHYPGGQTLPTPKAIDFTPGQLLG... |
anterograde axonal protein transport anterograde dendritic transport of neurotransmitter receptor complex anterograde neuronal dense core vesicle transport axon guidance cellular response to type II interferon centrosome localization cytoplasm organization lysosome localization microtubule-based movement mitochondrion ... | axon cytoplasm; centriolar satellite; ciliary rootlet; cytolytic granule membrane; cytosol; dendrite cytoplasm; kinesin complex; membrane; microtubule; mitochondrion; perinuclear region of cytoplasm; phagocytic vesicle; vesicle | ATP binding ATP hydrolysis activity cadherin binding identical protein binding microtubule binding microtubule motor activity plus-end-directed microtubule motor activity protein-containing complex binding | Homo sapiens | 3D-structure Acetylation ATP-binding Coiled coil Cytoplasm Cytoskeleton Isopeptide bond Lysosome Membrane Methylation Microtubule Motor protein Nucleotide-binding Phosphoprotein Reference proteome Ubl conjugation | MADLAECNIK | MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQ... | anterograde axonal protein transport anterograde dendritic transport of neurotransmitter receptor complex anterograde neuronal dense core vesicle transport axon guidance cellular response to type II interferon centrosome localization cytoplasm organization lysosome localization microtubule-based movement mitochondrion ... |
glycine decarboxylation via glycine cleavage system one-carbon metabolic process | cytosol; glycine cleavage complex | glycine binding glycine dehydrogenase (decarboxylating) activity identical protein binding pyridoxal phosphate binding | Escherichia coli | Direct protein sequencing Oxidoreductase Pyridoxal phosphate Reference proteome | MTQTLSQLEN | MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQT... | glycine decarboxylation via glycine cleavage system one-carbon metabolic process cytosol; glycine cleavage complex glycine binding glycine dehydrogenase (decarboxylating) activity identical protein binding pyridoxal phosphate binding Escherichia coli Direct protein sequencing Oxidoreductase Pyridoxal phosphate Referenc... |
2-oxoglutarate metabolic process glyoxylate cycle isocitrate metabolic process NADP metabolic process tricarboxylic acid cycle | mitochondrion | isocitrate dehydrogenase (NADP+) activity magnesium ion binding NAD binding | Sus scrofa | 3D-structure Acetylation Direct protein sequencing Glyoxylate bypass Magnesium Manganese Metal-binding Mitochondrion NADP Oxidoreductase Reference proteome Transit peptide Tricarboxylic acid cycle | ARAAARHYAD | ARAAARHYADQRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKYKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV... | 2-oxoglutarate metabolic process glyoxylate cycle isocitrate metabolic process NADP metabolic process tricarboxylic acid cycle mitochondrion isocitrate dehydrogenase (NADP+) activity magnesium ion binding NAD binding Sus scrofa 3D-structure Acetylation Direct protein sequencing Glyoxylate bypass Magnesium Manganese Met... |
maturation of SSU-rRNA nuclear-transcribed mRNA catabolic process ribosomal large subunit biogenesis ribosomal large subunit export from nucleus rRNA processing | cytoplasm; nucleolus; nucleoplasm; nucleus; preribosome, large subunit precursor; small-subunit processome | large ribosomal subunit rRNA binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Nucleus Reference proteome Ribosome biogenesis | MPRSKRSKLV | MPRSKRSKLVTLAQTDKKGRENKERIFDEVREALDTYRYVWVLHLDDVRTPVLQEIRTSWAGSKLIMGKRKVLQKALGEKREEEYKENLYQLSKLCSGVTGLLFTDEDVNTVKEYFKSYVRSDYSRPNTKAPLTFTIPEGIVYSRGGQIPAEEDVPMIHSLEPTMRNKFEIPTKIKAGKITIDSPYLVCTEGEKLDVRQALILKQFGIAASEFKVKVSAYYDNDSSTVESTNINME | maturation of SSU-rRNA nuclear-transcribed mRNA catabolic process ribosomal large subunit biogenesis ribosomal large subunit export from nucleus rRNA processing cytoplasm; nucleolus; nucleoplasm; nucleus; preribosome, large subunit precursor; small-subunit processome large ribosomal subunit rRNA binding Saccharomyces c... |
mRNA 5'-splice site recognition mRNA splicing, via spliceosome | commitment complex; nucleus; spliceosomal complex; U1 snRNP; U2-type prespliceosome | RNA binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein | MSIWKEAKDA | MSIWKEAKDASGRIYYYNTLTKKSTWEKPKELISQEELLLRENGWKAAKTADGKVYYYNPTTRETSWTIPAFEKKVEPIAEQKHDTVSHAQVNGNRIALTAGEKQEPGRTINEEESQYANNSKLLNVRRRTKEEAEKEFITMLKENQVDSTWSFSRIISELGTRDPRYWMVDDDPLWKKEMFEKYLSNRSADQLLKEHNETSKFKEAFQKMLQNNSHIKYYTRWPTAKRLIADEPIYKHSVVNEKTKRQTFQDYIDTLIDTQKESKKKLKTQALKELREYLNGIITTSSSETFITWQQLLNHYVFDKSKRYMANRHFKVL... | mRNA 5'-splice site recognition mRNA splicing, via spliceosome commitment complex; nucleus; spliceosomal complex; U1 snRNP; U2-type prespliceosome RNA binding Saccharomyces cerevisiae 3D-structure Direct protein sequencing mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein... |
anterior/posterior axis specification cell differentiation forebrain development mesoderm formation negative regulation of DNA-templated transcription neural plate development regulation of DNA-templated transcription | nucleus | DNA-binding transcription factor activity protein domain specific binding sequence-specific DNA binding | Xenopus laevis | Developmental protein Differentiation DNA-binding Neurogenesis Nucleus Reference proteome Repressor Transcription Transcription regulation | MLNRVKLEIK | MLNRVKLEIKDPMDWNTMYQENEMYSGIHNMTNVLPSNSFLPNDVSTVTTSMPYMSNGLPGPVTSIQGNIGSLGSMPQGMVGSLAPPPSTAAYPLGYCQGESEFQRDPRTYRRNYSHAKPPYSYISLITMAIQQAPNKMMTLNEIYQWIIDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVPRSPEKPGKGSYWTLHPESGNMFENGCYLRRQKRFKCERSKSGEGEKKVNKPGEETGGNLKENPVGYDDCSSSRSPQAAVNDGGRDSTGSSIHQACGSSPVGLSPTSEQAGTASQLMYPLGLSNDGYLGLVGEDVHLKHD... | anterior/posterior axis specification cell differentiation forebrain development mesoderm formation negative regulation of DNA-templated transcription neural plate development regulation of DNA-templated transcription nucleus DNA-binding transcription factor activity protein domain specific binding sequence-specific DN... |
fatty acid biosynthetic process | chloroplast; chloroplast envelope; chloroplast stroma; mitochondrion; nucleus; plastid | 3-oxoacyl- reductase (NADPH) activity copper ion binding NAD binding | Arabidopsis thaliana | Acetylation Chloroplast Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism NADP Oxidoreductase Plastid Reference proteome Transit peptide | MAAAVAAPRL | MAAAVAAPRLISLKAVAKLGFREISQIRQLAPLHSAIPHFGMLRCRSRQPFSTSVVKAQATATEQSPGEVVQKVESPVVVITGASRGIGKAIALALGKAGCKVLVNYARSAKEAEEVAKQIEEYGGQAITFGGDVSKATDVDAMMKTALDKWGTIDVVVNNAGITRDTLLIRMKQSQWDEVIALNLTGVFLCTQAAVKIMMKKKRGRIINISSVVGLIGNIGQANYAAAKGGVISFSKTAAREGASRNINVNVVCPGFIASDMTAELGEDMEKKILGTIPLGRYGKAEEVAGLVEFLALSPAASYITGQAFTIDGGIAI | fatty acid biosynthetic process chloroplast; chloroplast envelope; chloroplast stroma; mitochondrion; nucleus; plastid 3-oxoacyl- reductase (NADPH) activity copper ion binding NAD binding Arabidopsis thaliana Acetylation Chloroplast Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism NADP ... |
cell division microtubule depolymerization microtubule nucleation microtubule polymerization or depolymerization mitotic cell cycle regulation of establishment of protein localization | apical part of cell; centriole; centrosome; ciliary basal body; cytoplasm; cytosol; fibrillar center; gamma-tubulin ring complex; nucleoplasm; pericentriolar material; spindle pole | gamma-tubulin binding | Mus musculus | Alternative splicing Cell cycle Cell division Cytoplasm Cytoskeleton Mitosis Phosphoprotein Reference proteome Repeat WD repeat | MQENLRFASS | MQENLRFASSGDDVKIWDASFLTLVDKFNPHTSPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVDLNSTSMYLASGGLNNTVNIWDLKSKRLHRSLKDHKCEVTCVAYNWNDCYIASGSLSGEIILHSVTTNTSSTPFGHGSKQPIRHIKYSLFRKSLLGSVSDNGVVTLWDVNSQSSYHTFDSTHKAPASGICFSPVNELLFVTIGLDKRIILYDTSSKKLVKTLVADTPLTAVDFMPDGATLAIGSSRGKIYQYDLRMLKSPVKTISAHKTSVQCIAFQYSTSLTKASLSKGSSNKATA... | cell division microtubule depolymerization microtubule nucleation microtubule polymerization or depolymerization mitotic cell cycle regulation of establishment of protein localization apical part of cell; centriole; centrosome; ciliary basal body; cytoplasm; cytosol; fibrillar center; gamma-tubulin ring complex; nucleo... |
de novo' IMP biosynthetic process | cytosol | acetate kinase activity ATP binding ligase activity magnesium ion binding phosphoribosylglycinamide formyltransferase 2 activity phosphoribosylglycinamide formyltransferase activity | Escherichia coli | 3D-structure Acetylation ATP-binding Direct protein sequencing Ligase Magnesium Metal-binding Nucleotide-binding Purine biosynthesis Reference proteome | MTLLGTALRP | MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWKYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGP... | de novo' IMP biosynthetic process cytosol acetate kinase activity ATP binding ligase activity magnesium ion binding phosphoribosylglycinamide formyltransferase 2 activity phosphoribosylglycinamide formyltransferase activity Escherichia coli 3D-structure Acetylation ATP-binding Direct protein sequencing Ligase Magnesium... |
DNA damage response negative regulation of DNA-templated transcription | cytoplasm | acyl-CoA dehydrogenase activity DNA binding identical protein binding isovaleryl-CoA dehydrogenase activity sequence-specific DNA binding | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing DNA-binding FAD Flavoprotein Oxidoreductase Reference proteome Stress response | MHWQTHTVFN | MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLASIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHNLAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPLLSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFSVPQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDAIGWLLGLEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYH... | DNA damage response negative regulation of DNA-templated transcription cytoplasm acyl-CoA dehydrogenase activity DNA binding identical protein binding isovaleryl-CoA dehydrogenase activity sequence-specific DNA binding Escherichia coli 3D-structure Cytoplasm Direct protein sequencing DNA-binding FAD Flavoprotein Oxidor... |
aerobic respiration anaerobic electron transport chain anaerobic respiration regulation of pH | outer membrane-bounded periplasmic space; trimethylamine-N-oxide reductase (cytochrome c) complex | electron transfer activity molybdenum ion binding molybdopterin cofactor binding trimethylamine-N-oxide reductase (cytochrome c) activity trimethylamine-N-oxide reductase activity | Escherichia coli | Direct protein sequencing Metal-binding Molybdenum Oxidoreductase Periplasm Reference proteome Signal | MNNNDLFQAS | MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYC... | aerobic respiration anaerobic electron transport chain anaerobic respiration regulation of pH outer membrane-bounded periplasmic space; trimethylamine-N-oxide reductase (cytochrome c) complex electron transfer activity molybdenum ion binding molybdopterin cofactor binding trimethylamine-N-oxide reductase (cytochrome c)... |
aerobic respiration anaerobic electron transport chain anaerobic respiration negative regulation of signal transduction regulation of pH | Gram-negative-bacterium-type cell wall; membrane; outer membrane-bounded periplasmic space; plasma membrane; trimethylamine-N-oxide reductase (cytochrome c) complex | electron transfer activity heme binding iron ion binding | Escherichia coli | Cell inner membrane Cell membrane Electron transport Heme Iron Membrane Metal-binding Reference proteome Transmembrane Transmembrane helix Transport | MRKLWNALRR | MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQMKVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAY... | aerobic respiration anaerobic electron transport chain anaerobic respiration negative regulation of signal transduction regulation of pH Gram-negative-bacterium-type cell wall; membrane; outer membrane-bounded periplasmic space; plasma membrane; trimethylamine-N-oxide reductase (cytochrome c) complex electron transfer ... |
aerobic respiration L-fucose catabolic process lactate oxidation | plasma membrane | FMN binding L-lactate dehydrogenase activity | Escherichia coli | Cell inner membrane Cell membrane Flavoprotein FMN Membrane Oxidoreductase Reference proteome | MIISAASDYR | MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIA... | aerobic respiration L-fucose catabolic process lactate oxidation plasma membrane FMN binding L-lactate dehydrogenase activity Escherichia coli Cell inner membrane Cell membrane Flavoprotein FMN Membrane Oxidoreductase Reference proteome MIISAASDYR MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMP... |
cellular response to nerve growth factor stimulus mRNA 3'-end processing | cleavage body; mRNA cleavage and polyadenylation specificity factor complex; nuclear body; nucleoplasm | mRNA binding RNA binding | Homo sapiens | 3D-structure Alternative splicing Isopeptide bond Methylation mRNA processing Nucleus Phosphoprotein Reference proteome Repeat RNA-binding Ubl conjugation | MAGLTVRDPA | MAGLTVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKILHRQTNIPTLIAGNPQPVHGAGPGSGSNVSMNQQNPQAPQAQSLGGMHVNGAPPLMQASMQGGVPAPGQMPAAVTGPGPGSLAPGGGMQAQVGMPGSGPVSMERGQVPMQDPRAAMQRGSLPANVPTPRG... | cellular response to nerve growth factor stimulus mRNA 3'-end processing cleavage body; mRNA cleavage and polyadenylation specificity factor complex; nuclear body; nucleoplasm mRNA binding RNA binding Homo sapiens 3D-structure Alternative splicing Isopeptide bond Methylation mRNA processing Nucleus Phosphoprotein Refer... |
cellular defense response cellular response to interleukin-7 chemotaxis signal transduction | actin cytoskeleton; extracellular exosome; membrane; plasma membrane | actin binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cell membrane Direct protein sequencing Membrane Phosphoprotein Reference proteome | MAEASSDPGA | MAEASSDPGAEEREELLGPTAQWSVEDEEEAVHEQCQHERDRQLQAQDEEGGGHVPERPKQEMLLSLKPSEAPELDEDEGFGDWSQRPEQRQQHEGAQGALDSGEPPQCRSPEGEQEDRPGLHAYEKEDSDEVHLEELSLSKEGPGPEDTVQDNLGAAGAEEEQEEHQKCQQPRTPSPLVLEGTIEQSSPPLSPTTKLIDRTESLNRSIEKSNSVKKSQPDLPISKIDQWLEQYTQAIETAGRTPKLARQASIELPSMAVASTKSRWETGEVQAQSAAKTPSCKDIVAGDMSKKSLWEQKGGSKTSSTIKSTPSGKRYKF... | cellular defense response cellular response to interleukin-7 chemotaxis signal transduction actin cytoskeleton; extracellular exosome; membrane; plasma membrane actin binding Homo sapiens 3D-structure Acetylation Alternative splicing Cell membrane Direct protein sequencing Membrane Phosphoprotein Reference proteome MAE... |
adrenal gland development calcineurin-mediated signaling female gonad development hormone metabolic process hormone-mediated signaling pathway Leydig cell differentiation luteinization maintenance of protein location in nucleus male gonad development male sex determination negative regulation of female gonad developmen... | cytosol; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | chromatin binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding enzyme binding nuclear receptor activity phospholipid binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II ... | Mus musculus | 3D-structure Acetylation Activator Alternative splicing DNA-binding Isopeptide bond Lipid-binding Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MDYSYDEDLD | MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPPPDYMLPPSLHAPEPKALVSGPPSGPLGDFGAPSLPMAVPGPHGPLAGYLYPAFSNRTIKSEYPEPYASPPQQPGPPYSYPEPFSGGPNVPELILQLLQLEPEEDQVRARIVGCLQEPAKSRSDQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVLDHIYRQVQYGK... | adrenal gland development calcineurin-mediated signaling female gonad development hormone metabolic process hormone-mediated signaling pathway Leydig cell differentiation luteinization maintenance of protein location in nucleus male gonad development male sex determination negative regulation of female gonad developmen... |
epoxygenase P450 pathway linoleic acid metabolic process retinoic acid metabolic process retinol metabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; plasma membrane | arachidonic acid epoxygenase activity aromatase activity heme binding iron ion binding linoleic acid epoxygenase activity monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one at... | Homo sapiens | 3D-structure Alternative splicing Endoplasmic reticulum Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Signal | MDPAVALVLC | MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNNFPALIDYLPGSHNKIAENFAYIKSYVLERIKEHQESLDMNSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT... | epoxygenase P450 pathway linoleic acid metabolic process retinoic acid metabolic process retinol metabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; plasma membrane arachidonic acid epoxygenase activity aromatase activity heme binding iron ... |
epoxygenase P450 pathway heterocycle metabolic process long-chain fatty acid metabolic process monoterpenoid metabolic process omega-hydroxylase P450 pathway steroid metabolic process xenobiotic catabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle; plasma membrane | (R)-limonene 6-monooxygenase activity (S)-limonene 6-monooxygenase activity (S)-limonene 7-monooxygenase activity arachidonic acid epoxygenase activity aromatase activity enzyme binding heme binding iron ion binding long-chain fatty acid omega-1 hydroxylase activity monooxygenase activity oxidoreductase activity oxidor... | Homo sapiens | 3D-structure Direct protein sequencing Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase NADP Oxidoreductase Reference proteome | MDPFVVLVLC | MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVT... | epoxygenase P450 pathway heterocycle metabolic process long-chain fatty acid metabolic process monoterpenoid metabolic process omega-hydroxylase P450 pathway steroid metabolic process xenobiotic catabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded orga... |
fatty acid metabolic process | endoplasmic reticulum membrane; mitochondrial inner membrane | aromatase activity heme binding Hsp70 protein binding Hsp90 protein binding iron ion binding | Macaca fascicularis | Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Mitochondrion Mitochondrion inner membrane Monooxygenase NADP Oxidoreductase Reference proteome | LFQLELKNIP | LFQLELKNIPKSFTRLAQRFGPVFTLYVGSRRVVVVHGIKAVKEVLPGPQGRVLGQRRHPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKRFDYNDEKFLRLMYLFNENFQGLSCPWLQLYNNFPSLLHYLPGSHRKVMKNVAEIKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMHAVVHEIQRFITLV... | fatty acid metabolic process endoplasmic reticulum membrane; mitochondrial inner membrane aromatase activity heme binding Hsp70 protein binding Hsp90 protein binding iron ion binding Macaca fascicularis Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Mitochondrio... |
epoxygenase P450 pathway naphthalene catabolic process response to toxic substance trichloroethylene metabolic process xenobiotic metabolic process | cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle | arachidonic acid epoxygenase activity heme binding iron ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxygen binding | Mus musculus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MDGVSTAILL | MDGVSTAILLLLLAVISLSLTFSSRGKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSPRDFIDCFLTKMAQEKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKV... | epoxygenase P450 pathway naphthalene catabolic process response to toxic substance trichloroethylene metabolic process xenobiotic metabolic process cytoplasm; endoplasmic reticulum membrane; intracellular membrane-bounded organelle arachidonic acid epoxygenase activity heme binding iron ion binding monooxygenase activi... |
arachidonic acid metabolic process icosanoid metabolic process leukotriene B4 catabolic process omega-hydroxylase P450 pathway response to toxic substance | endoplasmic reticulum membrane | arachidonic acid binding arachidonic acid monooxygenase activity heme binding iron ion binding leukotriene-B4 20-monooxygenase activity | Rattus norvegicus | Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MSQLSLSWLG | MSQLSLSWLGLGPEVAFPWQTLLLFGASWILAQILTQIYAAYRNFRRLRGFPQPPKRNWLMGHVGMVTPTEQGLKELTRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKPWLGDGLLVSAGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISEGSSRLDMFEHVSLMTLDSLQKCVFSFDSNCQEKSSEYIAAILELSALVAKRHQQPLLFMDLLYNLTPDGMRFHKACNLVHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKDEDGKELSDEDIRA... | arachidonic acid metabolic process icosanoid metabolic process leukotriene B4 catabolic process omega-hydroxylase P450 pathway response to toxic substance endoplasmic reticulum membrane arachidonic acid binding arachidonic acid monooxygenase activity heme binding iron ion binding leukotriene-B4 20-monooxygenase activit... |
negative regulation of Ras protein signal transduction positive regulation of mating projection assembly signal transduction involved in positive regulation of conjugation with cellular fusion | cell cortex; cell cortex of cell tip; cell periphery; cortical dynamic polarity patch; cytosol; division septum; mating projection; nucleus | GTPase activator activity | Schizosaccharomyces pombe | GTPase activation Reference proteome | MTKRHSGTLS | MTKRHSGTLSSSVLPQTNRLSLLRNRESTSVLYTIDLDMESDVEDAFFHLDRELHDLKQQISSQSKQNFVLERDVRYLDSKIALLIQNRMAQEEQHEFAKRLNDNYNAVKGSFPDDRKLQLYGALFFLLQSEPAYIASLVRRVKLFNMDALLQIVMFNIYGNQYESREEHLLLSLFQMVLTTEFEATSDVLSLLRANTPVSRMLTTYTRRGPGQAYLRSILYQCINDVAIHPDLQLDIHPLSVYRYLVNTGQLSPSEDDNLLTNEEVSEFPAVKNAIQERSAQLLLLTKRFLDAVLNSIDEIPYGIRWVCKLIRNLTNRL... | negative regulation of Ras protein signal transduction positive regulation of mating projection assembly signal transduction involved in positive regulation of conjugation with cellular fusion cell cortex; cell cortex of cell tip; cell periphery; cortical dynamic polarity patch; cytosol; division septum; mating project... |
HRI-mediated signaling integrated stress response signaling negative regulation of cell population proliferation negative regulation of hemoglobin biosynthetic process negative regulation of translation peptidyl-serine phosphorylation protein autophosphorylation regulation of translation regulation of translational ini... | cytoplasm; cytosol | ATP binding eukaryotic translation initiation factor 2alpha kinase activity heme binding protein homodimerization activity protein serine kinase activity protein serine/threonine kinase activity | Oryctolagus cuniculus | ATP-binding Cytoplasm Direct protein sequencing Disulfide bond Kinase Nucleotide-binding Phosphoprotein Protein synthesis inhibitor Reference proteome Repeat Serine/threonine-protein kinase Transferase | MLGGSAGTRG | MLGGSAGTRGGEAEGDGAGAVGAVAPPPAIDFPAEVSDPKYDESDVPAELQVLKEPLQQPAFPFAVANQLLLVSLLEHLSHVHEPNPLRSRQVFKLLCQTFIKMGLLSSFTCSDEFSSLRLHHNRAITHLMRSARERVRQDPCADNSHIQKIRSREVALEAQTSRYLNEFEELSILGKGGYGRVYKVRNKLDGQYYAIKKILIKGATKTDCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVHVQADRVPIQLPSLEVLSDQEEDRDQYGVKNDASSSSSIIFAEFSPEKEKSSDECAVESQNNKLVNYTTNLVVRDTGE... | HRI-mediated signaling integrated stress response signaling negative regulation of cell population proliferation negative regulation of hemoglobin biosynthetic process negative regulation of translation peptidyl-serine phosphorylation protein autophosphorylation regulation of translation regulation of translational ini... |
aromatic amino acid family catabolic process to alcohol via Ehrlich pathway pyruvate metabolic process | cytosol | identical protein binding magnesium ion binding pyruvate decarboxylase activity thiamine pyrophosphate binding | Neurospora crassa | Cytoplasm Decarboxylase Direct protein sequencing Lyase Magnesium Metal-binding Reference proteome Thiamine pyrophosphate | MVAQQQGKFT | MVAQQQGKFTVGDYLAERLAQVGVRHHFVVPGDYNLILLDKLQAHPDLKEVGCANELNCSLAAEGYARANGISACVVTYSVGALSAFNGTGSAYAENLPLVLISGSPNTNDPSQYHILHHTLGHPDYTYQYEMAKKITCCAVAIPRAIDAPRLIDRALRAAILARKPCYIEIPTNLAGATCVRPGPISAITDPITSDKSALEAAAKCAAEYLDGKLKPVILVGPKAGRAGSEKELIEFAEAMGCAVALQPAAKGMFPEDHKQFVGIFWGQVSSDAADAMVHWADAMICVGAVFNDYSTVGWTAVPNIPLMTVDMDHVTFP... | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway pyruvate metabolic process cytosol identical protein binding magnesium ion binding pyruvate decarboxylase activity thiamine pyrophosphate binding Neurospora crassa Cytoplasm Decarboxylase Direct protein sequencing Lyase Magnesium Metal-binding ... |
protein monoubiquitination protein polyubiquitination ubiquitin-dependent ERAD pathway | endoplasmic reticulum; endoplasmic reticulum membrane; nucleus | ATP binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity | Saccharomyces cerevisiae | ATP-binding Endoplasmic reticulum Membrane Nucleotide-binding Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix Ubl conjugation pathway | MATKQAHKRL | MATKQAHKRLTKEYKLMVENPPPYILARPNEDNILEWHYIITGPADTPYKGGQYHGTLTFPSDYPYKPPAIRMITPNGRFKPNTRLCLSMSDYHPDTWNPGWSVSTILNGLLSFMTSDEATTGSITTSDHQKKTLARNSISYNTFQNVRFKLIFPEVVQENVETLEKRKLDEGDAANTGDETEDPFTKAAKEKVISLEEILDPEDRIRAEQALRQSENNSKKDGKEPNDSSSMVYIGIAIFLFLVGLFMK | protein monoubiquitination protein polyubiquitination ubiquitin-dependent ERAD pathway endoplasmic reticulum; endoplasmic reticulum membrane; nucleus ATP binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activity Saccharomyces cerevisiae ATP-binding Endoplasmic reticulum Membrane Nucleotide-b... |
positive regulation of RNA polymerase II transcription preinitiation complex assembly proteasome regulatory particle assembly proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process | cytoplasm; nucleus; proteasome complex; proteasome regulatory particle, base subcomplex | ATP binding ATP hydrolysis activity proteasome-activating activity | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Cytoplasm Direct protein sequencing Nucleotide-binding Nucleus Phosphoprotein Proteasome Reference proteome | MATLEELDAQ | MATLEELDAQTLPGDDELDQEILNLSTQELQTRAKLLDNEIRIFRSELQRLSHENNVMLEKIKDNKEKIKNNRQLPYLVANVVEVMDMNEIEDKENSESTTQGGNVNLDNTAVGKAAVVKTSSRQTVFLPMVGLVDPDKLKPNDLVGVNKDSYLILDTLPSEFDSRVKAMEVDEKPTETYSDVGGLDKQIEELVEAIVLPMKRADKFKDMGIRAPKGALMYGPPGTGKTLLARACAAQTNATFLKLAAPQLVQMYIGEGAKLVRDAFALAKEKAPTIIFIDELDAIGTKRFDSEKSGDREVQRTMLELLNQLDGFSSDDR... | positive regulation of RNA polymerase II transcription preinitiation complex assembly proteasome regulatory particle assembly proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process cytoplasm; nucleus; proteasome complex; proteasome regulatory particle, base subco... |
positive regulation of RNA polymerase II transcription preinitiation complex assembly proteasome regulatory particle assembly proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process | cytoplasm; nucleus; proteasome complex; proteasome regulatory particle, base subcomplex | ATP binding ATP hydrolysis activity identical protein binding proteasome-activating activity | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Cytoplasm Direct protein sequencing Isopeptide bond Nucleotide-binding Nucleus Proteasome Reference proteome Ubl conjugation | MEELGIVTPV | MEELGIVTPVEKAVEEKPAVKSYASLLAQLNGTVNNNSALSNVNSDIYFKLKKLEKEYELLTLQEDYIKDEQRHLKRELKRAQEEVKRIQSVPLVIGQFLEPIDQNTGIVSSTTGMSYVVRILSTLDRELLKPSMSVALHRHSNALVDILPPDSDSSISVMGENEKPDVTYADVGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVLLYGPPGTGKTMLVKAVANSTKAAFIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQSTNVKVIMATNR... | positive regulation of RNA polymerase II transcription preinitiation complex assembly proteasome regulatory particle assembly proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process cytoplasm; nucleus; proteasome complex; proteasome regulatory particle, base subco... |
positive regulation of protein catabolic process positive regulation of RNA polymerase II transcription preinitiation complex assembly proteasome regulatory particle assembly proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process | cytoplasm; nucleus; proteasome complex; proteasome regulatory particle, base subcomplex | ATP binding ATP hydrolysis activity proteasome-activating activity ubiquitin protein ligase binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm Nucleotide-binding Nucleus Phosphoprotein Proteasome Reference proteome | MPPKEDWEKY | MPPKEDWEKYKAPLEDDDKKPDDDKIVPLTEGDIQVLKSYGAAPYAAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSHLWDIMGDRQRLGEEHPLQVARCTKIIKGNGESDETTTDNNNSGNSNSNSNQQSTDADEDDEDAKYVINLKQIAKFVVGLGERVSPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDVTYSDVGGCKDQIEKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATFIRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFD... | positive regulation of protein catabolic process positive regulation of RNA polymerase II transcription preinitiation complex assembly proteasome regulatory particle assembly proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process cytoplasm; nucleus; proteasome co... |
glycosphingolipid biosynthetic process mannosyl diphosphorylinositol ceramide metabolic process mannosyl-inositol phosphorylceramide biosynthetic process mannosyl-inositol phosphorylceramide metabolic process sphingolipid biosynthetic process | fungal-type vacuole; fungal-type vacuole membrane; Golgi apparatus; mannosyltransferase complex | inositol phosphorylceramide mannosyltransferase activity mannosyltransferase activity | Saccharomyces cerevisiae | Glycosyltransferase Membrane Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix | MRKELKYLIC | MRKELKYLICFNILLLLSIIYYTFDLLTLCIDDTVKDAILEEDLNPDAPPKPQLIPKIIHQTYKTEDIPEHWKEGRQKCLDLHPDYKYILWTDEMAYEFIKEEYPWFLDTFENYKYPIERADAIRYFILSHYGGVYIDLDDGCERKLDPLLAFPAFLRKTSPLGVSNDVMGSVPRHPFFLKALKSLKHYDKYWFIPYMTIMGSTGPLFLSVIWKQYKRWRIPKNGTVRILQPAYYKMHSYSFFSITKGSSWHLDDAKLMKALENHILSCVVTGFIFGFFILYGEFTFYCWLCSKNFSNLTKNWKLNAIKVRFVTILNSLG... | glycosphingolipid biosynthetic process mannosyl diphosphorylinositol ceramide metabolic process mannosyl-inositol phosphorylceramide biosynthetic process mannosyl-inositol phosphorylceramide metabolic process sphingolipid biosynthetic process fungal-type vacuole; fungal-type vacuole membrane; Golgi apparatus; mannosylt... |
base-excision repair double-strand break repair double-strand break repair via nonhomologous end joining maintenance of DNA trinucleotide repeats meiotic DNA double-strand break formation mitochondrial double-strand break repair via homologous recombination sporulation resulting in formation of a cellular spore telomer... | Mre11 complex; nucleoplasm; nucleus | DNA binding double-stranded telomeric DNA binding G-quadruplex DNA binding protein-macromolecule adaptor activity single-stranded telomeric DNA binding telomeric DNA binding | Saccharomyces cerevisiae | DNA damage DNA repair Meiosis Phosphoprotein Reference proteome | MWVVRYQNTL | MWVVRYQNTLEDGSISFISCCLQAFKTYSIGRSSKNPLIIKNDKSISRQHITFKWEINNSSDLKHSSLCLVNKGKLTSLNKKFMKVGETFTINASDVLKSTIIELGTTPIRIEFEWINEVWNIPPHLTQFRTMLSEYGISTEISINDIPANLMISDYPKSEDNSIRELYALVSTIPMKKSRFLMELCNTLLPTSKTNLKFDEMWNDMISNPEYNVFDFDPNILLSKFMRLNNIRVLTTIKSEPRLSSLLRTFNINLFAFDNIDSLYKYVDSLEASTEYLILTTTDKKENGKILCTIKTMLTSIIDGTLSAVINMKGASSR... | base-excision repair double-strand break repair double-strand break repair via nonhomologous end joining maintenance of DNA trinucleotide repeats meiotic DNA double-strand break formation mitochondrial double-strand break repair via homologous recombination sporulation resulting in formation of a cellular spore telomer... |
cell cycle cell division positive regulation of protein export from nucleus protein export from nucleus protein import into nucleus snRNA import into nucleus | cytosol; nuclear envelope; protein-containing complex | nuclear export signal receptor activity small GTPase binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Cell division Cytoplasm Mitosis Nucleus Protein transport Reference proteome Repeat Transport | MSDLETVAKF | MSDLETVAKFLAESVIASTAKTSERNLRQLETQDGFGLTLLHVIASTNLPLSTRLAGALFFKNFIKRKWVDENGNHLLPANNVELIKKEIVPLMISLPNNLQVQIGEAISSIADSDFPDRWPTLLSDLASRLSNDDMVTNKGVLTVAHSIFKRWRPLFRSDELFLEIKLVLDVFTAPFLNLLKTVDEQITANENNKASLNILFDVLLVLIKLYYDFNCQDIPEFFEDNIQVGMGIFHKYLSYSNPLLEDPDETEHASVLIKVKSSIQELVQLYTTRYEDVFGPMINEFIQITWNLLTSISNQPKYDILVSKSLSFLTAVT... | cell cycle cell division positive regulation of protein export from nucleus protein export from nucleus protein import into nucleus snRNA import into nucleus cytosol; nuclear envelope; protein-containing complex nuclear export signal receptor activity small GTPase binding Saccharomyces cerevisiae 3D-structure Cell cyc... |
negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II RNA polymerase II preinitiation complex assembly | core mediator complex; cytosol; mediator complex; nucleus | structural molecule activity transcription coactivator activity | Saccharomyces cerevisiae | 3D-structure Activator Nucleus Reference proteome Transcription Transcription regulation | MNLQNNVLNQ | MNLQNNVLNQIHQILLPTNPTLDKPNAEATKEEFSSAENRDEKDYLTNQQPKNLSTPSTSSNGEFIPHIFYSLHQIRKDPNNLSNQLETLTGSIRHRLKLCKSLISENEDTKDLLSKSPSEWQDIIHQREQELQIKRDVLDDLYRKLQR | negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II RNA polymerase II preinitiation complex assembly core mediator com... |
cell division meiotic cell cycle nonfunctional rRNA decay nuclear-transcribed mRNA catabolic process, no-go decay nuclear-transcribed mRNA catabolic process, non-stop decay positive regulation of translation positive regulation of translational initiation rescue of stalled ribosome ribosome disassembly RNA surveillance... | cytoplasm; Dom34-Hbs1 complex | metal ion binding RNA endonuclease activity | Saccharomyces cerevisiae | 3D-structure Cell cycle Cell division Cytoplasm Meiosis Metal-binding Mitosis Protein biosynthesis Reference proteome Translation regulation | MKVISLKKDS | MKVISLKKDSFNKGGAVITLLPEDKEDLFTVYQIVDKDDELIFKKKFTSKLDEAGKKKSTDLVKLKIKVISEDFDMKDEYLKYKGVTVTDESGASNVDIPVGKYLSFTLDYVYPFTIIKQNFNKFMQKLLNEACNIEYKSDTAAVVLQEGIAHVCLVTSSSTILKQKIEYSMPKKKRTTDVLKFDEKTEKFYKAIYSAMKKDLNFDKLKTIILCSPGFYAKILMDKIFQYAEEEHNKKILDNKGMFFIAHCSTGYLQGINEVLKNPLYASKLQDTKYSKEIMVMDEFLLHLNKDDDKAWYGEKEVVKAAEYGAISYLLLT... | cell division meiotic cell cycle nonfunctional rRNA decay nuclear-transcribed mRNA catabolic process, no-go decay nuclear-transcribed mRNA catabolic process, non-stop decay positive regulation of translation positive regulation of translational initiation rescue of stalled ribosome ribosome disassembly RNA surveillance... |
oligopeptide export from mitochondrion | mitochondrial inner membrane; mitochondrion | ABC-type oligopeptide transporter activity ATP binding ATP hydrolysis activity | Saccharomyces cerevisiae | ATP-binding Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Reference proteome Transit peptide Transmembrane Transmembrane helix Transport | MIVRMIRLCK | MIVRMIRLCKGPKLLRSQFASASALYSTKSLFKPPMYQKAEINLIIPHRKHFLLRSIRLQSDIAQGKKSTKPTLKLSNANSKSSGFKDIKRLFVLSKPESKYIGLALLLILISSSVSMAVPSVIGKLLDLASESDGEDEEGSKSNKLYGFTKKQFFTALGAVFIIGAVANASRIIILKVTGERLVARLRTRTMKAALDQDATFLDTNRVGDLISRLSSDASIVAKSVTQNVSDGTRAIIQGFVGFGMMSFLSWKLTCVMMILAPPLGAMALIYGRKIRNLSRQLQTSVGGLTKVAEEQLNATRTIQAYGGEKNEVRRYAK... | oligopeptide export from mitochondrion mitochondrial inner membrane; mitochondrion ABC-type oligopeptide transporter activity ATP binding ATP hydrolysis activity Saccharomyces cerevisiae ATP-binding Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Reference proteome Transit peptide Transmembrane ... |
protein folding protein refolding | cytoplasm; nucleus | Hsp70 protein binding Hsp90 protein binding ribosome binding | Saccharomyces cerevisiae | 3D-structure Chaperone Cytoplasm Reference proteome Repeat TPR repeat | MSSVNANGGY | MSSVNANGGYTKPQKYVPGPGDPELPPQLSEFKDKTSDEILKEMNRMPFFMTKLDETDGAGGENVELEALKALAYEGEPHEIAENFKKQGNELYKAKRFKDARELYSKGLAVECEDKSINESLYANRAACELELKNYRRCIEDCSKALTINPKNVKCYYRTSKAFFQLNKLEEAKSAATFANQRIDPENKSILNMLSVIDRKEQELKAKEEKQQREAQERENKKIMLESAMTLRNITNIKTHSPVELLNEGKIRLEDPMDFESQLIYPALIMYPTQDEFDFVGEVSELTTVQELVDLVLEGPQERFKKEGKENFTPKKVL... | protein folding protein refolding cytoplasm; nucleus Hsp70 protein binding Hsp90 protein binding ribosome binding Saccharomyces cerevisiae 3D-structure Chaperone Cytoplasm Reference proteome Repeat TPR repeat MSSVNANGGY MSSVNANGGYTKPQKYVPGPGDPELPPQLSEFKDKTSDEILKEMNRMPFFMTKLDETDGAGGENVELEALKALAYEGEPHEIAENFKKQGNELYKAKRF... |
DNA replication dTMP biosynthetic process dUMP biosynthetic process dUTP catabolic process liver development nucleobase-containing compound metabolic process regulation of protein-containing complex assembly response to organic cyclic compound | extracellular exosome; mitochondrion; nucleoplasm; nucleus | dUTP diphosphatase activity identical protein binding magnesium ion binding peroxisome proliferator activated receptor binding pyrimidine deoxyribonucleotide binding RNA binding signaling receptor inhibitor activity | Homo sapiens | 3D-structure Alternative splicing Diabetes mellitus Direct protein sequencing Disease variant Hydrolase Magnesium Mitochondrion Nucleotide metabolism Nucleus Phosphoprotein Reference proteome Transit peptide | MTPLCPRPAL | MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSAGRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTERGSGGFGSTGKN | DNA replication dTMP biosynthetic process dUMP biosynthetic process dUTP catabolic process liver development nucleobase-containing compound metabolic process regulation of protein-containing complex assembly response to organic cyclic compound extracellular exosome; mitochondrion; nucleoplasm; nucleus dUTP diphosphatas... |
dITP catabolic process dUMP biosynthetic process dUTP catabolic process pyrimidine deoxyribonucleoside triphosphate catabolic process | cytoplasm; nucleus | dITP diphosphatase activity dUTP diphosphatase activity magnesium ion binding | Saccharomyces cerevisiae | 3D-structure Hydrolase Magnesium Metal-binding Nucleotide metabolism Reference proteome | MTATSDKVLK | MTATSDKVLKIQLRSASATVPTKGSATAAGYDIYASQDITIPAMGQGMVSTDISFTVPVGTYGRIAPRSGLAVKNGIQTGAGVVDRDYTGEVKVVLFNHSQRDFAIKKGDRVAQLILEKIVDDAQIVVVDSLEESARGAGGFGSTGN | dITP catabolic process dUMP biosynthetic process dUTP catabolic process pyrimidine deoxyribonucleoside triphosphate catabolic process cytoplasm; nucleus dITP diphosphatase activity dUTP diphosphatase activity magnesium ion binding Saccharomyces cerevisiae 3D-structure Hydrolase Magnesium Metal-binding Nucleotide metab... |
box H/ACA RNA 3'-end processing cell cycle cell division mRNA pseudouridine synthesis rRNA modification rRNA processing rRNA pseudouridine synthesis snoRNA guided rRNA pseudouridine synthesis snRNA pseudouridine synthesis | 90S preribosome; box H/ACA snoRNP complex; chromosome, centromeric region; cytoplasm; microtubule | DNA binding mRNA binding pseudouridine synthase activity | Saccharomyces cerevisiae | 3D-structure Cell cycle Cell division Centromere Chromosome Cytoplasm Cytoskeleton Direct protein sequencing DNA-binding Isomerase Isopeptide bond Microtubule Mitosis Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein Ribosome biogenesis RNA-binding rRNA processing Ubl conjugation | MSKEDFVIKP | MSKEDFVIKPEAAGASTDTSEWPLLLKNFDKLLVRSGHYTPIPAGSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDLGRSLENLTGALFQRPPLISAVKRQLRVRTIYESNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNMVTLHDVMDAQWVYDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEIVLITTKGEAIAVAIAQM... | box H/ACA RNA 3'-end processing cell cycle cell division mRNA pseudouridine synthesis rRNA modification rRNA processing rRNA pseudouridine synthesis snoRNA guided rRNA pseudouridine synthesis snRNA pseudouridine synthesis 90S preribosome; box H/ACA snoRNP complex; chromosome, centromeric region; cytoplasm; microtubule ... |
ascospore-type prospore assembly endocytosis exocytosis Golgi to endosome transport Golgi to plasma membrane transport Golgi vesicle fusion to target membrane intracellular protein transport retrograde transport, endosome to Golgi sporulation vesicle fusion vesicle fusion to plasma membrane vesicle fusion with Golgi ap... | cell periphery; cellular bud; cytosol; endosome; endosome membrane; Golgi membrane; plasma membrane; prospore membrane; SNARE complex; trans-Golgi network; transport vesicle membrane | molecular adaptor activity SNAP receptor activity syntaxin binding | Saccharomyces cerevisiae | Coiled coil Isopeptide bond Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Transmembrane Transmembrane helix Ubl conjugation | MSSSVPYDPY | MSSSVPYDPYVPPEESNSGANPNSQNKTAALRQEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAISAQGFKRGANRVRKQMWWKDLKMRMCLFLVVIILLVVIIVPIVVHFS | ascospore-type prospore assembly endocytosis exocytosis Golgi to endosome transport Golgi to plasma membrane transport Golgi vesicle fusion to target membrane intracellular protein transport retrograde transport, endosome to Golgi sporulation vesicle fusion vesicle fusion to plasma membrane vesicle fusion with Golgi ap... |
L-serine biosynthetic process purine nucleobase biosynthetic process serine family amino acid biosynthetic process | cytoplasm | O-phospho-L-serine:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding | Saccharomyces cerevisiae | 3D-structure Amino-acid biosynthesis Aminotransferase Phosphoprotein Pyridoxal phosphate Reference proteome Serine biosynthesis Transferase | MSLEREEPQH | MSLEREEPQHFGAGPAQMPTPVLQQAAKDLINFNDIGLGIGEISHRSKDATKVIEDSKKHLIELLNIPDTHEVFYLQGGGTTGFSSVATNLAAAYVGKHGKIAPAGYLVTGSWSQKSFEEAKRLHVPAEVIFNAKDYNNGKFGKIPDESLWEDKIKGKAFSYVYLCENETVHGVEWPELPKCLVNDPNIEIVADLSSDILSRKIDVSQYGVIMAGAQKNIGLAGLTLYIIKKSILKNISGASDETLHELGVPITPIAFDYPTVVKNNSAYNTIPIFTLHVMDLVFQHILKKGGVEAQQAENEEKAKILYEALDANSDFYN... | L-serine biosynthetic process purine nucleobase biosynthetic process serine family amino acid biosynthetic process cytoplasm O-phospho-L-serine:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding Saccharomyces cerevisiae 3D-structure Amino-acid biosynthesis Aminotransferase Phosphoprotein Pyridoxal ph... |
CDP-diacylglycerol biosynthetic process glycerophospholipid biosynthetic process phosphatidic acid biosynthetic process | endoplasmic reticulum; lipid droplet; membrane | 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltransferase activity | Saccharomyces cerevisiae | Acyltransferase Lipid biosynthesis Lipid droplet Lipid metabolism Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase | MSVIGRFLYY | MSVIGRFLYYLRSVLVVLALAGCGFYGVIASILCTLIGKQHLAQWITARCFYHVMKLMLGLDVKVVGEENLAKKPYIMIANHQSTLDIFMLGRIFPPGCTVTAKKSLKYVPFLGWFMALSGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIPIVPVVVSNTSTLVSPKYGVFNRGCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSPAINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVNTHNEGSSVKKMH | CDP-diacylglycerol biosynthetic process glycerophospholipid biosynthetic process phosphatidic acid biosynthetic process endoplasmic reticulum; lipid droplet; membrane 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltrans... |
actin cortical patch assembly actin filament organization clathrin coat assembly endocytosis negative regulation of Arp2/3 complex-mediated actin nucleation | actin cortical patch; cellular bud neck; cellular bud tip; clathrin-coated vesicle; incipient cellular bud site; mating projection tip; plasma membrane | actin filament binding clathrin adaptor activity clathrin light chain binding phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol-3,5-bisphosphate binding | Saccharomyces cerevisiae | 3D-structure Actin-binding Cell membrane Cytoplasm Cytoskeleton Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MSRIDSDLQK | MSRIDSDLQKALKKACSVEETAPKRKHVRACIVYTWDHQSSKAVFTTLKTLPLANDEVQLFKMLIVLHKIIQEGHPSALAEAIRDRDWIRSLGRVHSGGSSYSKLIREYVRYLVLKLDFHAHHRGFNNGTFEYEEYVSLVSVSDPDEGYETILDLMSLQDSLDEFSQIIFASIQSERRNTECKISALIPLIAESYGIYKFITSMLRAMHRQLNDAEGDAALQPLKERYELQHARLFEFYADCSSVKYLTTLVTIPKLPVDAPDVFLINDVDESKEIKFKKREPSVTPARTPARTPTPTPPVVAEPAISPRPVSQRTTSTP... | actin cortical patch assembly actin filament organization clathrin coat assembly endocytosis negative regulation of Arp2/3 complex-mediated actin nucleation actin cortical patch; cellular bud neck; cellular bud tip; clathrin-coated vesicle; incipient cellular bud site; mating projection tip; plasma membrane actin filam... |
tRNA processing | nucleolus; nucleoplasm; nucleus; polysome | mRNA binding RNA binding tRNA binding U6 snRNA binding | Saccharomyces cerevisiae | Acetylation Methylation Nucleus Phosphoprotein Reference proteome RNA-binding | MSEKPQQEEQ | MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEFNFPYDRFLRTTAEKNDGWVPISTIATFNRMKKYRPVDKVIEALRSSEILEVSADGENVKRRVPLDLTAARNARIEQNQRTLAVMNFPHEDVEASQIPELQENLEAFFKKLGEINQVRLRRDHRNKKFNGTVLVEFKTIPECEAFLKSYSNDDESNEILSYEGKKLSVLTKKQFDLQREASKSKNFSGRSRSFNGHKKKNLPKFPKNKKKNGKEESKEDSSAIADDDEEHKE | tRNA processing nucleolus; nucleoplasm; nucleus; polysome mRNA binding RNA binding tRNA binding U6 snRNA binding Saccharomyces cerevisiae Acetylation Methylation Nucleus Phosphoprotein Reference proteome RNA-binding MSEKPQQEEQ MSEKPQQEEQEKPQSRRNSFAVIEFTPEVLDRCLKQVEFYFSEFNFPYDRFLRTTAEKNDGWVPISTIATFNRMKKYRPVDKVIEALRSSEI... |
ascospore formation cellular response to alkaline pH cellular response to anoxia fungal-type cell wall biogenesis meiotic cell cycle negative regulation of transcription by RNA polymerase II positive regulation of division septum assembly positive regulation of transcription by RNA polymerase II | cytoplasm; nucleus | DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific zinc ion binding | Saccharomyces cerevisiae | Activator Cytoplasm DNA-binding Meiosis Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MVPLEDLLNK | MVPLEDLLNKENGTAAPQHSRESIVENGTDVSNVTKKDGLPSPNLSKRSSDCSKRPRIRCTTEAIGLNGQEDERMSPGSTSSSCLPYHSTSHLNTPPYDLLGASAVSPTTSSSSDSSSSSPLAQAHNPAGDDDDADNDGDSEDITLYCKWDNCGMIFNQPELLYNHLCHDHVGRKSHKNLQLNCHWGDCTTKTEKRDHITSHLRVHVPLKPFGCSTCSKKFKRPQDLKKHLKIHLESGGILKRKRGPKWGSKRTSKKNKSCASDAVSSCSASVPSAIAGSFKSHSTSPQILPPLPVGISQHLPSQQQQRAISLNQLCSDE... | ascospore formation cellular response to alkaline pH cellular response to anoxia fungal-type cell wall biogenesis meiotic cell cycle negative regulation of transcription by RNA polymerase II positive regulation of division septum assembly positive regulation of transcription by RNA polymerase II cytoplasm; nucleus DNA ... |
carbohydrate metabolic process galactose catabolic process glucose 1-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycogen biosynthetic process trehalose biosynthetic process UDP-glucose metabolic process | cytoplasm; cytosol | magnesium ion binding phosphoglucomutase activity | Saccharomyces cerevisiae | Acetylation Carbohydrate metabolism Cytoplasm Glucose metabolism Isomerase Magnesium Metal-binding Phosphoprotein Reference proteome | MSLLIDSVPT | MSLLIDSVPTVAYKDQKPGTSGLRKKTKVFMDEPHYTENFIQATMQSIPNGSEGTTLVVGGDGRFYNDVIMNKIAAVGAANGVRKLVIGQGGLLSTPAASHIIRTYEEKCTGGGIILTASHNPGGPENDLGIKYNLPNGGPAPESVTNAIWEASKKLTHYKIIKNFPKLNLNKLGKNQKYGPLLVDIIDPAKAYVQFLKEIFDFDLIKSFLAKQRKDKGWKLLFDSLNGITGPYGKAIFVDEFGLPAEEVLQNWHPLPDFGGLHPDPNLTYARTLVDRVDREKIAFGAASDGDGDRNMIYGYGPAFVSPGDSVAIIAEYA... | carbohydrate metabolic process galactose catabolic process glucose 1-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycogen biosynthetic process trehalose biosynthetic process UDP-glucose metabolic process cytoplasm; cytosol magnesium ion binding phosphoglucomutase activity... |
cGMP-mediated signaling nitric oxide mediated signal transduction positive regulation of nitric oxide mediated signal transduction response to oxygen levels signal transduction | cytosol; guanylate cyclase complex, soluble | GTP binding guanylate cyclase activity heme binding | Homo sapiens | Alternative splicing cGMP biosynthesis Cytoplasm GTP-binding Lyase Nucleotide-binding Reference proteome | MSRRKISSES | MSRRKISSESFSSLGSDYLETSPEEEGECPLSRLCWNGSRSPPGPLEPSPAAAAAAAAPAPTPAASAAAAAATAGARRVQRRRRVNLDSLGESISRLTAPSPQTIQQTLKRTLQYYEHQVIGYRDAEKNFHNISNRCSYADHSNKEEIEDVSGILQCTANILGLKFEEIQKRFGEEFFNICFHENERVLRAVGGTLQDFFNGFDALLEHIRTSFGKQATLESPSFLCKELPEGTLMLHYFHPHHIVGFAMLGMIKAAGKKIYRLDVEVEQVANEKLCSDVSNPGNCSCLTFLIKECENTNIMKNLPQGTSQVPADLRISI... | cGMP-mediated signaling nitric oxide mediated signal transduction positive regulation of nitric oxide mediated signal transduction response to oxygen levels signal transduction cytosol; guanylate cyclase complex, soluble GTP binding guanylate cyclase activity heme binding Homo sapiens Alternative splicing cGMP biosynth... |
putrescine transport spermidine transport urea transport | cell periphery; endoplasmic reticulum; plasma membrane | putrescine transmembrane transporter activity spermidine transmembrane transporter activity urea transmembrane transporter activity | Saccharomyces cerevisiae | Membrane Reference proteome Transmembrane Transmembrane helix Transport | MGEFKPPLPQ | MGEFKPPLPQGAGYAIVLGLGAVFAGMMVLTTYLLKRYQKEIITAEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSSTKEYADGIFGGYAYAAGACFQIIAFAILAIKTKQMAPNAHTYLELVRTRYGKIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIASCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIIIIVLVFAFKVYATSDVLGSPGKVYDLVREAAKRHPVDGNYQGEYMTMTSKSAGILLIINLIGNFGTVFLDNGYWNKAISASPAASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSP... | putrescine transport spermidine transport urea transport cell periphery; endoplasmic reticulum; plasma membrane putrescine transmembrane transporter activity spermidine transmembrane transporter activity urea transmembrane transporter activity Saccharomyces cerevisiae Membrane Reference proteome Transmembrane Transmem... |
cellular response to heat mitochondrial genome maintenance protein refolding protein stabilization protein unfolding | cytoplasm; mitochondrial matrix; mitochondrion | ATP binding ATP hydrolysis activity misfolded protein binding | Saccharomyces cerevisiae | ATP-binding Chaperone Coiled coil Direct protein sequencing Mitochondrion Nucleotide-binding Reference proteome Repeat Stress response Transit peptide | MLRQATKAPI | MLRQATKAPIQKYLQRTQLLRRSTPRIYTIVQCKRSICSFNARPRVANKLLSDIKTNALNEVAISTCALKSSYGLPNFKRTYVQMRMDPNQQPEKPALEQFGTNLTKLARDGKLDPVIGRDEEIARAIQILSRRTKNNPCLIGRAGVGKTALIDGLAQRIVAGEVPDSLKDKDLVALDLGSLIAGAKYRGEFEERLKKVLEEIDKANGKVIVFIDEVHMLLGLGKTDGSMDASNILKPKLARGLRCISATTLDEFKIIEKDPALSRRFQPILLNEPSVSDTISILRGLKERYEVHHGVRITDTALVSAAVLSNRYITDRF... | cellular response to heat mitochondrial genome maintenance protein refolding protein stabilization protein unfolding cytoplasm; mitochondrial matrix; mitochondrion ATP binding ATP hydrolysis activity misfolded protein binding Saccharomyces cerevisiae ATP-binding Chaperone Coiled coil Direct protein sequencing Mitochon... |
regulation of microtubule nucleation spindle pole body duplication | central plaque of spindle pole body; cytoplasm; nucleus; spindle pole body | identical protein binding structural constituent of cytoskeleton | Saccharomyces cerevisiae | Cytoplasm Cytoskeleton Nucleus Phosphoprotein Reference proteome | MDYSNFGNSA | MDYSNFGNSASKKFQDDTLNRVRKEHEEALKKLREENFSSNTSELGNKKHYRAQERMSSPLHRLSPTGKSDDRKVKSPLDDKLRRQLREGNTRLPPPPFSSYGMPPTNRSNLDRIRRRTSSPVRTDKFASQNVIDDQRLEIKYLERIVYDQGTVIDNLTSRITRLESFILNSISDRGDKNFASLEHSRSFSGFPTNKTYGLQMGGLYENDMPYRRSSDNINKEGAREDRSSQIHIENESTEDILKILSSSFHN | regulation of microtubule nucleation spindle pole body duplication central plaque of spindle pole body; cytoplasm; nucleus; spindle pole body identical protein binding structural constituent of cytoskeleton Saccharomyces cerevisiae Cytoplasm Cytoskeleton Nucleus Phosphoprotein Reference proteome MDYSNFGNSA MDYSNFGNSAS... |
actin filament-based movement establishment of mitotic spindle orientation nuclear migration involved in conjugation with cellular fusion | actin cytoskeleton; cell tip; cytoplasm; dynactin complex; dynein complex; microtubule; microtubule associated complex; spindle; spindle pole | microtubule binding | Saccharomyces cerevisiae | Coiled coil Cytoplasm Cytoskeleton Dynein Microtubule Reference proteome | MRNAGVQVDT | MRNAGVQVDTNMQKISLQDTVLVNEMKGRVKFIGETQFAKGIWYGIELDKPLGKNDGSANGIRYFDIDLKKANSNGGYYGLFCKKDTLQFYKPDDDEHSLLNGNAAQETIKNLQVKCESLASKLNKIKIENHELKTSVEKLSTNETVLLSKISRLDKLVKELKVENGNMKTHLDNFNHLLDASDSVMAPDLDKGTLLERSHLLQGLLDQTKLSYDKAMKVQEDLLEENTQLLEENAVLSKKISDLGLQLQQTNNTIGDLALQIEAQSKSSNIVDKLTNDNILLTSNIKALNNELEELQAKEKLDENLRITYEQLEQELRL... | actin filament-based movement establishment of mitotic spindle orientation nuclear migration involved in conjugation with cellular fusion actin cytoskeleton; cell tip; cytoplasm; dynactin complex; dynein complex; microtubule; microtubule associated complex; spindle; spindle pole microtubule binding Saccharomyces cerevi... |
entry receptor-mediated virion attachment to host cell viral entry into host cell | extracellular region; host cell endoplasmic reticulum; host cell Golgi apparatus; host cell nucleus; host cell surface; T=1 icosahedral viral capsid | identical protein binding RNA binding structural molecule activity | Hepatitis E virus genotype 1 | 3D-structure Alternative initiation Capsid protein Glycoprotein Host cytoplasm Host endoplasmic reticulum Host Golgi apparatus Host nucleus Host-virus interaction RNA-binding Secreted Signal T=1 icosahedral capsid protein Viral attachment to host cell Viral attachment to host entry receptor Virion Virus entry into host... | MRPRPILLLL | MRPRPILLLLLMFLPMLPAPPPGQPSGRRRGRRSGGSGGGFWGDRVDSQPFAIPYIHPTNPFAPDVTAAAGAGPRVRQPARPLGSAWRDQAQRPAAASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYNLSTSPLTSSVATGTNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVARATIRYRPLVPNAVGGYAISISFWPQTTTTPTSVDMNSITSTDVRILVQPGIASELVIPSERLHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSPVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRV... | entry receptor-mediated virion attachment to host cell viral entry into host cell extracellular region; host cell endoplasmic reticulum; host cell Golgi apparatus; host cell nucleus; host cell surface; T=1 icosahedral viral capsid identical protein binding RNA binding structural molecule activity Hepatitis E virus geno... |
defense response to bacterium | extracellular region; membrane | nutrient reservoir activity toxin activity | Triticum aestivum | Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Membrane Plant defense Reference proteome Secreted Signal Toxin | MKALFLIGLL | MKALFLIGLLALVASTAFAQYSEVVGSYDVAGGGGAQQCPVETKLNSCRNYLLDRCSTMKDFPVTWRWWKWWKGGCQELLGECCSRLGQMPPQCRCNIIQGSIQGDLGGIFGFQRDRASKVIQEAKNLPPRCNQGPPCNIPGTIGYYW | defense response to bacterium extracellular region; membrane nutrient reservoir activity toxin activity Triticum aestivum Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Membrane Plant defense Reference proteome Secreted Signal Toxin MKALFLIGLL MKALFLIGLLALVASTAFAQYSEVVGSYDVAGGGGAQQCPVETKLNSCRNYLLDRCS... |
defense response to fungus fibrinolysis heme transport negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration negative regulation of cell adhesion negative regulation of cell adhesion mediated by integrin negative regulation of cell growth negative regulation of cell populati... | endolysosome; extracellular region | heme binding heparan sulfate proteoglycan binding heparin binding immunoglobulin binding metal ion binding serine-type endopeptidase inhibitor activity signaling receptor binding zinc ion binding | Bos taurus | Blood coagulation Copper Direct protein sequencing Disulfide bond Fibrinolysis Glycoprotein Hemostasis Heparin-binding Phosphoprotein Reference proteome Repeat Secreted Zinc | AVNPTGCDAV | AVNPTGCDAVEPVAVRALDLINKGRDGYLFQLLRVADAHLDKVESIAVYYLVESDCPVLSRKHWDDCELNVTVIGQCKLAGPEDLSVNDFNCTTSSVSSALTNMRARGGEGTSYFLDFSVRNCSSHHFPRHHIFGFCRADLFYDVEASDLETPKDIVTNCEVFHRRFSAVQHHLGRPFHSGEHEHSPAGRPPFKPSGSKDHGHPHESYNFRCPPPLEHKNHSDSPPFQARAPLPFPPPGLRCPHPPFGTKGNHRPPHDHSSDEHHPHGHHPHGHHPHGHHPHGHHPPDNDFYDHGPCDPPPHRPPPRHSKERGPGKGHFR... | defense response to fungus fibrinolysis heme transport negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration negative regulation of cell adhesion negative regulation of cell adhesion mediated by integrin negative regulation of cell growth negative regulation of cell populati... |
bone mineralization bone morphogenesis collagen catabolic process endochondral ossification extracellular matrix disassembly extracellular matrix organization growth plate cartilage development heart development positive regulation of pancreatic trypsinogen secretion protein catabolic process protein metabolic process ... | extracellular matrix; extracellular region; extracellular space; intercellular canaliculus | calcium ion binding calcium-dependent protein binding collagen binding endopeptidase activity fibronectin binding low-density lipoprotein particle receptor binding metalloendopeptidase activity peptidase activity zinc ion binding | Mus musculus | 3D-structure Calcium Collagen degradation Direct protein sequencing Disulfide bond Extracellular matrix Glycoprotein Hydrolase Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MHSAILATFF | MHSAILATFFLLSWTPCWSLPLPYGDDDDDDLSEEDLVFAEHYLKSYYHPATLAGILKKSTVTSTVDRLREMQSFFGLEVTGKLDDPTLDIMRKPRCGVPDVGEYNVFPRTLKWSQTNLTYRIVNYTPDMSHSEVEKAFRKAFKVWSDVTPLNFTRIYDGTADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFIVAAHELGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQFLYGPGDEDPNPKHPKTPEKCDPALSLDAITSLRGETMIFKDRFFWRLHPQQVEAE... | bone mineralization bone morphogenesis collagen catabolic process endochondral ossification extracellular matrix disassembly extracellular matrix organization growth plate cartilage development heart development positive regulation of pancreatic trypsinogen secretion protein catabolic process protein metabolic process ... |
DNA recombination mRNA export from nucleus mRNA processing transcription elongation by RNA polymerase II | chromosome, telomeric region; nucleoplasmic THO complex; THO complex part of transcription export complex; transcription export complex | molecular adaptor activity nucleic acid binding | Saccharomyces cerevisiae | 3D-structure Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MPLSQKQIDQ | MPLSQKQIDQVRTKVHYSEVDTPFNKYLDILGKVTKLTGSIINGTLSNDDSKIEKLTEQNISQLKESAHLRFLDLQSSIDTKKVADENWETCQQETLAKLENLKDKLPDIKSIHSKLLLRIGKLQGLYDSVQVINREVEGLSEGRTSLVVTRAEWEKELGTDLVKFLIEKNYLKLVDPGLKKDSSEERYRIYDDFSKGPKELESINASMKSDIENVRQEVSSYKEKWLRDAEIFGKITSIFKEELLKRDGLLNEAEGDNIDEDYESDEDEERKERFKRQRSMVEVNTIENVDEKEESDHEYDDQEDEENEEEDDMEVDVE... | DNA recombination mRNA export from nucleus mRNA processing transcription elongation by RNA polymerase II chromosome, telomeric region; nucleoplasmic THO complex; THO complex part of transcription export complex; transcription export complex molecular adaptor activity nucleic acid binding Saccharomyces cerevisiae 3D-st... |
cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 90S preribosome; cytosol; cytosolic small ribosomal subunit | structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Isopeptide bond Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MAVGKNKRLS | MAVGKNKRLSKGKKGQKKRVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVCLADLQGSEDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGEEKGKKVTGFKDEVLETV | cytoplasmic translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 90S preribosome; cytosol; cytosolic small ribosomal subunit structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Isopeptide bond Phosphoprotein Reference proteome R... |
cytokinesis by cell plate formation positive regulation of cell division positive regulation of cell size positive regulation of DNA endoreduplication unidimensional cell growth | endoplasmic reticulum lumen; plasma membrane | auxin binding zinc ion binding | Arabidopsis thaliana | Auxin signaling pathway Cell membrane Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Membrane Metal-binding Receptor Reference proteome Signal Ubl conjugation Zinc | MIVLSVGSAS | MIVLSVGSASSSPIVVVFSVALLLFYFSETSLGAPCPINGLPIVRNISDLPQDNYGRPGLSHMTVAGSVLHGMKEVEIWLQTFAPGSETPIHRHSCEEVFVVLKGSGTLYLAETHGNFPGKPIEFPIFANSTIHIPINDAHQVKNTGHEDLQVLVIISRPPIKIFIYEDWFMPHTAARLKFPYYWDEQCIQESQKDEL | cytokinesis by cell plate formation positive regulation of cell division positive regulation of cell size positive regulation of DNA endoreduplication unidimensional cell growth endoplasmic reticulum lumen; plasma membrane auxin binding zinc ion binding Arabidopsis thaliana Auxin signaling pathway Cell membrane Direct ... |
cell cycle positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | chromatin; MBF transcription complex; nucleus; SBF transcription complex | DNA-binding transcription activator activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Schizosaccharomyces pombe | ANK repeat Cell cycle DNA-binding Reference proteome Repeat | MYNDQIHKIT | MYNDQIHKITYSGVEVFEYTINGFPLMKRCHDNWLNATQILKIAELDKPRRTRILEKFAQKGLHEKIQGGCGKYQGTWVPSERAVELAHEYNVFDLIQPLIEYSGSAFMPMSTFTPQSNRKPTEAYRRNSPVKKSFSRPSHSLLYPYTSSNNMTSTSRMSGIHDALSLQSDFTRSPDMPSDSFTGSLHDIKASPFSSNNYAQSLLDYFLLPNTTQPPDFVYDRPSDWDVNAGIDEDGHTALHWAAAMGNLEMMHALLQAGANVVAVNYLQQTSLMRCVMFTMNYDLQTFEVVSELLQSAICMNDSFGQTVFHHIALLASS... | cell cycle positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II chromatin; MBF transcription complex; nucleus; SBF transcription complex DNA-binding transcription activator activity, RNA polymerase II-specific RNA p... |
pyridoxal transmembrane transport pyridoxamine transmembrane transport pyridoxine transmembrane transport thiamine transmembrane transport transmembrane transport | fungal-type vacuole; plasma membrane | pyridoxal transmembrane transporter activity pyridoxamine transmembrane transporter activity pyridoxine transmembrane transporter activity thiamine transmembrane transporter activity transmembrane transporter activity | Schizosaccharomyces pombe | Membrane Reference proteome Transmembrane Transmembrane helix Transport | MASKIASLFS | MASKIASLFSPSETASKDQHENVAEDLELGTASSQSDGIHETNSEYDEKKREESPEVIDISNLISSDHPAHPQNWHWAKRWSIVFMFCLMQIYVIWTSNGFGSIEYSVMAQFNVSAQVATLCLSMNILGSGLGPMFLGPLSDIGGRKPVYFCSIFVYTVFNISCALPRNIVQMIISHFIIGVAGSTALTNVAGGIPDLFPEDTAGVPMSLFVWACAGGAIGAPMATGVDINAKYGWRWLYYINIIVGGFFLIVILIIPETLPIKVITRYENAKGRIVEGIPKNNLKEVLKKCKFVTTMGFRMMLTEPIILSMGLYNFYAY... | pyridoxal transmembrane transport pyridoxamine transmembrane transport pyridoxine transmembrane transport thiamine transmembrane transport transmembrane transport fungal-type vacuole; plasma membrane pyridoxal transmembrane transporter activity pyridoxamine transmembrane transporter activity pyridoxine transmembrane tr... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adult locomotory behavior cellular response to growth factor stimulus cellular response to hypoxia cellular response to toxic substance eating behavior G protein-coupled opioid receptor signaling pathway G protein-coupled receptor signaling pathw... | axon terminus; dendrite membrane; membrane; neuron projection; neuronal dense core vesicle; plasma membrane; postsynaptic density membrane; postsynaptic membrane; presynaptic membrane; spine apparatus; synaptic vesicle membrane; vesicle | G protein-coupled enkephalin receptor activity G protein-coupled opioid receptor activity neuropeptide binding receptor serine/threonine kinase binding | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix Ubl conjugation | MEPVPSARAE | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAF... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adult locomotory behavior cellular response to growth factor stimulus cellular response to hypoxia cellular response to toxic substance eating behavior G protein-coupled opioid receptor signaling pathway G protein-coupled receptor signaling pathw... |
adenylate cyclase-inhibiting opioid receptor signaling pathway behavioral response to cocaine cellular response to glucose stimulus conditioned place preference defense response to virus eating behavior G protein-coupled opioid receptor signaling pathway immune response locomotory behavior maternal behavior negative re... | axon terminus; cytosol; dendrite; membrane; neuron projection; neuronal cell body; nucleoplasm; perikaryon; plasma membrane; postsynaptic membrane; presynaptic membrane; synaptic vesicle membrane | dynorphin receptor activity G protein-coupled opioid receptor activity neuropeptide binding receptor serine/threonine kinase binding | Mus musculus | Behavior Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MESPIQIFRG | MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGY... | adenylate cyclase-inhibiting opioid receptor signaling pathway behavioral response to cocaine cellular response to glucose stimulus conditioned place preference defense response to virus eating behavior G protein-coupled opioid receptor signaling pathway immune response locomotory behavior maternal behavior negative re... |
blood coagulation liver development negative regulation of apoptotic process negative regulation of blood coagulation negative regulation of coagulation negative regulation of inflammatory response positive regulation of establishment of endothelial barrier protein catabolic process proteolysis regulation of circulatin... | endoplasmic reticulum; extracellular space; Golgi apparatus | calcium ion binding oligopeptidase activity peptidase activity protein self-association serine-type endopeptidase activity | Mus musculus | Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Endoplasmic reticulum Gamma-carboxyglutamic acid Glycoprotein Golgi apparatus Hemostasis Hydrolase Hydroxylation Protease Reference proteome Repeat Secreted Serine protease Signal Zymogen | MWQFRVFLLL | MWQFRVFLLLMSTWGISSIPAHPDPVFSSSEHAHQVLRVRRANSFLEEMRPGSLERECMEEICDFEEAQEIFQNVEDTLAFWIKYFDGDQCSAPPLDHQCDSPCCGHGTCIDGIGSFSCSCDKGWEGKFCQQELRFQDCRVNNGGCLHYCLEESNGRRCACAPGYELADDHMRCKSTVNFPCGKLGRWIEKKRKILKRDTDLEDELEPDPRIVNGTLTKQGDSPWQAILLDSKKKLACGGVLIHTSWVLTAAHCVEGTKKLTVRLGEYDLRRRDHWELDLDIKEILVHPNYTRSSSDNDIALLRLAQPATLSKTIVPICL... | blood coagulation liver development negative regulation of apoptotic process negative regulation of blood coagulation negative regulation of coagulation negative regulation of inflammatory response positive regulation of establishment of endothelial barrier protein catabolic process proteolysis regulation of circulatin... |
proteolysis | extracellular region | serine-type endopeptidase activity toxin activity | Lachesis muta muta | Blood coagulation cascade activating toxin Direct protein sequencing Disulfide bond Glycoprotein Hemostasis impairing toxin Hydrolase Protease Secreted Serine protease Toxin | VIGGDECNIN | VIGGDECNINEHRFLVALYDGLSGTFLCGGTLINQEWVLTAQHCNRSLMNIYLGMHNKNVKFDDEQRRYPKKKYFFRCNKNFTKWDEDIRLNRPVRFSAHIEPLSLPSNPPSEDSVCRVMGWGQITSPPETLPDVPHCANINLFNYTVCRGAYPRMPTKVLCAGVLEGGIDTCNRDSGGPLICNGQFQGIVFWGPDPCAQPDKPGVYTKVFDYLDWIQSVIAGNTTCS | proteolysis extracellular region serine-type endopeptidase activity toxin activity Lachesis muta muta Blood coagulation cascade activating toxin Direct protein sequencing Disulfide bond Glycoprotein Hemostasis impairing toxin Hydrolase Protease Secreted Serine protease Toxin VIGGDECNIN VIGGDECNINEHRFLVALYDGLSGTFLCGGTLI... |
estrogen metabolic process fatty acid metabolic process retinol metabolic process steroid biosynthetic process | endoplasmic reticulum membrane; mitochondrial inner membrane | aromatase activity estrogen 16-alpha-hydroxylase activity estrogen 2-hydroxylase activity heme binding Hsp70 protein binding Hsp90 protein binding hydroperoxy icosatetraenoate dehydratase activity iron ion binding | Macaca fascicularis | Cytoplasm Endoplasmic reticulum Glycoprotein Heme Iron Lipid biosynthesis Lipid metabolism Lyase Membrane Metal-binding Microsome Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroid biosynthesis | MLFRISMSAT | MLFRISMSATEFLLASLIFCLVFWVIRASRPRVPKGLKNPPGPWGWPLIGHILTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSGLDTIRQALVQQGDDFKGRPNLYSFTLISNGQSMSFGPDSGPVWAARRRLAQNGLKSFSIASDPASSSSCYLEEHVSKEAEVLISKLQEQMAGPGHFNPYRYVVISVANVICAICFGQRYDHNHQELLSLVNLSNNFGEVVGSGNPADFIPILRYLPNRSLNGFKDLNEKFHSFMQKMIKEHYKTFEKGYIRDITDSLIEHCQEKQLDENANIQLSDEKIVNVVLDLFGAGFD... | estrogen metabolic process fatty acid metabolic process retinol metabolic process steroid biosynthetic process endoplasmic reticulum membrane; mitochondrial inner membrane aromatase activity estrogen 16-alpha-hydroxylase activity estrogen 2-hydroxylase activity heme binding Hsp70 protein binding Hsp90 protein binding h... |
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity | external side of plasma membrane; extracellular space; MHC class I protein complex | peptide antigen binding signaling receptor binding | Macaca mulatta | Disulfide bond Glycoprotein Immunity Membrane MHC I Reference proteome Signal Transmembrane Transmembrane helix | MAPRTLLLVL | MAPRTLLLVLSGALALTETWAGSHSLRYFSTAVSRPGRREPQYRYIAVEYVDDTQFLRFDSDAAIPRMEPRAPWVEQEGPQYWERTTGYAKANARTDRVALRKLLLRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVARITQRFYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDREATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPQPLTLRWESSSQPTIPIVGIVAGLAVLAVV... | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib immune response positive regulation of T cell mediated cytotoxicity external side of plasma membrane; extracellular space; ... |
immune response positive regulation of NF-kappaB transcription factor activity regulation of biological quality regulation of developmental process regulation of multicellular organismal process regulation of secretion vascular endothelial growth factor production | extracellular space; plasma membrane | cytokine activity tumor necrosis factor receptor binding | Papio sp. | Cell membrane Cytokine Disulfide bond Glycoprotein Lipoprotein Membrane Myristate Phosphoprotein Secreted Signal-anchor Transmembrane Transmembrane helix | MSTESMIRDV | MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLLVAGATTLFCLLHFGVIGPQREEFPKDPSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINLPDYLDFAESGQVYFGIIAL | immune response positive regulation of NF-kappaB transcription factor activity regulation of biological quality regulation of developmental process regulation of multicellular organismal process regulation of secretion vascular endothelial growth factor production extracellular space; plasma membrane cytokine activity ... |
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