Biological Process
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Cellular Component
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Molecular Function
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Organism
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Keywords
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Sequence 10
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Sequence
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1.02k
Combined
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136
3.91k
regulation of cell projection assembly
plasma membrane
ATP binding phosphorelay sensor kinase activity
Pseudomonas aeruginosa
ATP-binding Cell inner membrane Cell membrane Kinase Membrane Nucleotide-binding Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix Two-component regulatory system
MRAERLRLSE
MRAERLRLSEEQGQRILRLYHLYRLTIGLVLVLLISSELEDQVLKLVHPELFHVGSWCYLVFNILVALFLPPSRQLLPIFILALTDVLMLCGLFYAGGGVPSGIGSLLVVAVAIANILLRGRIGLVIAAAASLGLLYLTFFLSLSSPDATNHYVQAGGLGTLCFAAALVIQALVRRQEQTETLAEERAETVANLEELNALILQRMRTGILVVDSRQAILLANQAALGLLRQDDVQGASLGRHSPMLMHCMKQWRLNPSLRPPTLKVVPDGPTVQPSFISLNREDDQHVLIFLEDISQIAQQAQQMKLAGLGRLTAGIAHE...
regulation of cell projection assembly plasma membrane ATP binding phosphorelay sensor kinase activity Pseudomonas aeruginosa ATP-binding Cell inner membrane Cell membrane Kinase Membrane Nucleotide-binding Phosphoprotein Reference proteome Transferase Transmembrane Transmembrane helix Two-component regulatory system M...
enzyme-directed rRNA pseudouridine synthesis
cytosol
pseudouridine synthase activity RNA binding rRNA pseudouridine synthase activity
Escherichia coli
3D-structure Direct protein sequencing Isomerase Reference proteome RNA-binding rRNA processing
MAQRVQLTAT
MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQRVLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIIINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHK...
enzyme-directed rRNA pseudouridine synthesis cytosol pseudouridine synthase activity RNA binding rRNA pseudouridine synthase activity Escherichia coli 3D-structure Direct protein sequencing Isomerase Reference proteome RNA-binding rRNA processing MAQRVQLTAT MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQRVLVNGKVCDKPKEKVLGG...
peptidoglycan metabolic process
cytosol; outer membrane-bounded periplasmic space
2'-deoxyadenosine deaminase activity adenosine deaminase activity copper ion binding oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor protein homodimerization activity purine-nucleoside phosphorylase activity S-methyl-5-thioadenosine phosphorylase activity
Escherichia coli
3D-structure Copper Hydrolase Metal-binding Oxidoreductase Reference proteome Transferase Zinc
MSKLIVPQWP
MSKLIVPQWPQPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNPDHVEENRKRLFAAGNLPSKPVWLEQVHGKDVLKLTGEPYASKRADASYSNTPGTVCAVMTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPRAFEVGGEVREAFMAVDAKASAAFIQHGDKYLADIYQLARQRLANVGVEQIFGGDRCTYTENETFFSYRRDKTTGRMASFIWLI
peptidoglycan metabolic process cytosol; outer membrane-bounded periplasmic space 2'-deoxyadenosine deaminase activity adenosine deaminase activity copper ion binding oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor protein homodimerization activity purine-nucleoside pho...
mRNA catabolic process negative regulation of cell growth regulation of DNA-templated transcription regulation of growth regulation of mRNA stability rRNA catabolic process single-species biofilm formation
toxin-antitoxin complex
DNA binding RNA binding RNA endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters
Escherichia coli
DNA-binding Endonuclease Hydrolase Nuclease Reference proteome RNA-binding Toxin-antitoxin system
MVKKSEFERG
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLHARLAKRIGLAADEVVEEALLRLQAVVE
mRNA catabolic process negative regulation of cell growth regulation of DNA-templated transcription regulation of growth regulation of mRNA stability rRNA catabolic process single-species biofilm formation toxin-antitoxin complex DNA binding RNA binding RNA endonuclease activity RNA endonuclease activity, producing 5'-...
DNA damage response iron ion import across plasma membrane
plasma membrane
ferrous iron transmembrane transporter activity GTP binding identical protein binding
Escherichia coli
3D-structure Cell inner membrane Cell membrane GTP-binding Ion transport Iron Iron transport Membrane Nucleotide-binding Reference proteome Transmembrane Transmembrane helix Transport
MKKLTIGLIG
MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALKLAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVH...
DNA damage response iron ion import across plasma membrane plasma membrane ferrous iron transmembrane transporter activity GTP binding identical protein binding Escherichia coli 3D-structure Cell inner membrane Cell membrane GTP-binding Ion transport Iron Iron transport Membrane Nucleotide-binding Reference proteome Tr...
cell adhesion cell migration regulation of cell migration
axon; cell surface; membrane; microspike; plasma membrane; protein-containing complex
identical protein binding
Rattus norvegicus
Cell membrane Glycoprotein Heparan sulfate Membrane Phosphoprotein Proteoglycan Reference proteome Signal Transmembrane Transmembrane helix
MKPGPPRRGT
MKPGPPRRGTAQGQRVDTATHGPGARGLLLPPLLLLLLAGRAAGAQRWRNENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGLETAMRFIPDIALAAPTAPAMLPTTVIQPVDTPFEELLSEHPGPEPVTSPPLVTEVTEVVEEPSQRATTISTTTSTTAATTTGAPTMATAPATAATTAPSTPAAPPATATTADIRTTGIQGLLPLPLTTAATAKATTPAVPSPPTTVTTLDTEAPTPRLVNTATSRPRALPRPVTTQEPEVAERSTLPLGTTAPGPTEVAQTPTPESLLTTTQDEPEVPVSGGPSGDFEL...
cell adhesion cell migration regulation of cell migration axon; cell surface; membrane; microspike; plasma membrane; protein-containing complex identical protein binding Rattus norvegicus Cell membrane Glycoprotein Heparan sulfate Membrane Phosphoprotein Proteoglycan Reference proteome Signal Transmembrane Transmembran...
apoptotic process cell cycle double-strand break repair negative regulation of cysteine-type endopeptidase activity involved in apoptotic process peptidyl-serine phosphorylation positive regulation of aggrephagy positive regulation of cell growth positive regulation of cell population proliferation positive regulation ...
nucleus
ATP binding protein serine kinase activity protein serine/threonine kinase activity
Oryctolagus cuniculus
Apoptosis ATP-binding Biological rhythms Cell cycle Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase Wnt signaling pathway
MSGPVPSRVR
MSGPVPSRVRVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPASRTPALAFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAME...
apoptotic process cell cycle double-strand break repair negative regulation of cysteine-type endopeptidase activity involved in apoptotic process peptidyl-serine phosphorylation positive regulation of aggrephagy positive regulation of cell growth positive regulation of cell population proliferation positive regulation ...
cell surface receptor signaling pathway cellular response to lipopolysaccharide immune response intracellular signal transduction negative regulation of T cell mediated immunity positive regulation of DNA-templated transcription positive regulation of granulocyte macrophage colony-stimulating factor production positive...
cell surface; external side of plasma membrane; plasma membrane; protein complex involved in cell adhesion
coreceptor activity receptor ligand activity virus receptor activity
Homo sapiens
3D-structure Alternative splicing Direct protein sequencing Disulfide bond Glycoprotein Host cell receptor for virus entry Host-virus interaction Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix
MGHTRRQGTS
MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV
cell surface receptor signaling pathway cellular response to lipopolysaccharide immune response intracellular signal transduction negative regulation of T cell mediated immunity positive regulation of DNA-templated transcription positive regulation of granulocyte macrophage colony-stimulating factor production positive...
blood coagulation, intrinsic pathway negative regulation of angiogenesis negative regulation of blood coagulation negative regulation of endothelial cell migration negative regulation of endothelial cell proliferation negative regulation of fibrinolysis negative regulation of myeloid cell apoptotic process negative reg...
cell surface; chylomicron; high-density lipoprotein particle; very-low-density lipoprotein particle
heparin binding identical protein binding lipoprotein lipase activator activity phospholipid binding
Canis lupus familiaris
Disulfide bond Glycoprotein Heparin-binding Reference proteome Repeat Secreted Signal Sushi
MISLGLILFS
MISLGLILFSSVLCHVATAGRTCPKPDDIPFATVVPLKTFYDPGEQIAYTCQPGYVFRGLTRRFTCPLTGVWPTNTVRCIPRVCPFAGILENGAVRYTTFEYPNTISFACNTGFYLNGSSSAKCTEEGKWSVDLPVCTRVTCPPPSVPKFATLSVFKPLATNNSLYGNKAVFECLPHYAMFGNDTITCTAHGNWTTLPECREVKCPFPSRPDNGFVNYPAKQILYYKDKAMYGCHDTYTLDGPEVVECNKFGNWSAQPSCKASCKLSVKKATVLYQGERVKLQEKFKDGMLHGQKVSFYCKNKEKKCSYTEDAECIDGTI...
blood coagulation, intrinsic pathway negative regulation of angiogenesis negative regulation of blood coagulation negative regulation of endothelial cell migration negative regulation of endothelial cell proliferation negative regulation of fibrinolysis negative regulation of myeloid cell apoptotic process negative reg...
adaptive immune response cell adhesion cellular response to granulocyte macrophage colony-stimulating factor stimulus interleukin-15-mediated signaling pathway macrophage differentiation maintenance of protein location in cell positive regulation of canonical NF-kappaB signal transduction positive regulation of DNA-tem...
external side of plasma membrane; membrane raft
coreceptor activity interleukin-16 binding interleukin-16 receptor activity MHC class II protein binding MHC class II protein complex binding protein homodimerization activity protein tyrosine kinase binding zinc ion binding
Canis lupus familiaris
Adaptive immunity Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix
MNQEAAFRHL
MNQEAAFRHLLLMLQLVMLPAVTPVREVVLGKAGDAVELPCQTSQKKNIHFNWRDSSMVQILGNQGSFWTVGSSRLKHRVESKKNLWDQGSFPLVIKDLEVADSGIYFCDTDKRQEVELLVFNLTAKWDSGSSSGSSNIRLLQGQQLTLTLENPSGSSPSVQWKGPGNKSKHGGQNLSLSWPELQDGGTWTCIISQSQKTVEFNINVLVLAFQKVSNTFYAREGDQVEFSFPLSFEDENLVGELRWQAQGASSSLLWISFTLENRKLSMKEAHAPLKLQMKESLPLRFTLPQVLSRYAGSGILTLNLAKGTLYQEVNLVV...
adaptive immune response cell adhesion cellular response to granulocyte macrophage colony-stimulating factor stimulus interleukin-15-mediated signaling pathway macrophage differentiation maintenance of protein location in cell positive regulation of canonical NF-kappaB signal transduction positive regulation of DNA-tem...
anatomical structure development cell population proliferation insulin-like growth factor receptor signaling pathway negative regulation of apoptotic process negative regulation of release of cytochrome c from mitochondria negative regulation of smooth muscle cell apoptotic process positive regulation of cell populatio...
alphav-beta3 integrin-IGF-1-IGF1R complex; exocytic vesicle; extracellular space
growth factor activity hormone activity insulin-like growth factor receptor binding
Canis lupus familiaris
Disulfide bond Growth factor Reference proteome Secreted Signal
MGKISSLPTQ
MGKISSLPTQLFKCCFCDFLKVKMHTVSSSHLFYLALCLLTFPSPATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKAQKEVHLKNASRGSAGNKNYRM
anatomical structure development cell population proliferation insulin-like growth factor receptor signaling pathway negative regulation of apoptotic process negative regulation of release of cytochrome c from mitochondria negative regulation of smooth muscle cell apoptotic process positive regulation of cell populatio...
angiogenesis atrial cardiac muscle cell to AV node cell communication by electrical coupling atrial septum development cell-cell signaling gap junction assembly heart development mitral valve development outflow tract morphogenesis pulmonary valve formation regulation of atrial cardiac muscle cell action potential regu...
connexin complex; intercalated disc
gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling gap junction hemi-channel ...
Canis lupus familiaris
Cell junction Cell membrane Gap junction Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix
MGDWSFLGEF
MGDWSFLGEFLEEVHKHSTVIGKVWLTVLFIFRMLVLGTAAESSWGDEQADFQCDTMQPGCGNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEARGAGSYEYPVAEKAELSCWEEVNGRIVLQGTLLNTYVCSILIRTTMEVAFIVGQYLLYGIFLDTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLFLSLAELYHLGWKKLRQRFVKSGQGMAECQLPGPSAGIVQNCTPPPDFNQCLENGPGGKFFNPFSNKMASQQNTDNLATEQVQGQEPIPGEGFIHIRYAQK...
angiogenesis atrial cardiac muscle cell to AV node cell communication by electrical coupling atrial septum development cell-cell signaling gap junction assembly heart development mitral valve development outflow tract morphogenesis pulmonary valve formation regulation of atrial cardiac muscle cell action potential regu...
entrainment of circadian clock by photoperiod retina development in camera-type eye signal transduction visual perception
photoreceptor outer segment membrane
3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding
Canis lupus familiaris
Acetylation Cell projection cGMP Disease variant Hydrolase Lipoprotein Membrane Metal-binding Prenylation Reference proteome Repeat Sensory transduction Vision
MSLSEEQVQH
MSLSEEQVQHFLDQNPDFTDQYFGKTLSPEHVAGACGDGQPTDCASFRELCQVEESAALFELVQDMQESVNMERVVFKILRRLCTILRADRCSLFMYRQRNGVAELATRLFSVQPGSALEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVQDVTECPHFSPFADELTGYETRNILATPIMNGKDVVAVIMALNKLDGPCFTSEDEDVFLKYLNFGTLNLKIYHLSYLHNCETRRGQVLLWSANKVFEELTDIERQFHKAFYTVRAYLNCDRYSVGLLDMTKEKEFFDVWPVLMGEAQPYSGPRTPDGREIVFYKVIDYI...
entrainment of circadian clock by photoperiod retina development in camera-type eye signal transduction visual perception photoreceptor outer segment membrane 3',5'-cyclic-GMP phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity metal ion binding Canis lupus familiaris Acetylation Cell project...
colon epithelial cell migration positive regulation of neuron projection development regulation of epithelial cell migration
cell surface; lysosome
metal ion binding N-acetylgalactosamine-4-sulfatase activity
Felis catus
Calcium Disulfide bond Glycoprotein Hydrolase Lysosome Metal-binding Mucopolysaccharidosis Reference proteome Signal
MGRRGAASLP
MGRRGAASLPRGPSPRRPLLPGVLPLLLRLLLLPSRPGAGAGADRPPHLVFVLADDLGWNDVSFHGSNIRTPHLDELAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIHTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCALIDSLNVTRCALDFRDGEQVATGYKNMYSTNIFTERATALITSHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHYYAGMVSLMDEAVGNVTAALKSHGLWNNTVFIFSTDNGGQTLAGGNNWPLRGRK...
colon epithelial cell migration positive regulation of neuron projection development regulation of epithelial cell migration cell surface; lysosome metal ion binding N-acetylgalactosamine-4-sulfatase activity Felis catus Calcium Disulfide bond Glycoprotein Hydrolase Lysosome Metal-binding Mucopolysaccharidosis Referen...
SRP-dependent cotranslational protein targeting to membrane
cytosol; endoplasmic reticulum; signal recognition particle, endoplasmic reticulum targeting
7S RNA binding ribosome binding signal recognition particle binding TPR domain binding
Canis lupus familiaris
3D-structure Acetylation Cytoplasm Direct protein sequencing Endoplasmic reticulum Isopeptide bond Phosphoprotein Reference proteome Repeat Ribonucleoprotein Signal recognition particle TPR repeat Ubl conjugation
MASGGSGGVS
MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNAACALIGQGQLSQAMKILQKAEDLCRRSLSEDSDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQA...
SRP-dependent cotranslational protein targeting to membrane cytosol; endoplasmic reticulum; signal recognition particle, endoplasmic reticulum targeting 7S RNA binding ribosome binding signal recognition particle binding TPR domain binding Canis lupus familiaris 3D-structure Acetylation Cytoplasm Direct protein sequen...
glutamine metabolic process histidine biosynthetic process
cytoplasm
glutaminase activity imidazoleglycerol-phosphate synthase activity oxo-acid-lyase activity
Saccharomyces cerevisiae
3D-structure Amino-acid biosynthesis Glutamine amidotransferase Histidine biosynthesis Hydrolase Lyase Multifunctional enzyme Reference proteome Stress response
MPVVHVIDVE
MPVVHVIDVESGNLQSLTNAIEHLGYEVQLVKSPKDFNISGTSRLILPGVGNYGHFVDNLFNRGFEKPIREYIESGKPIMGICVGLQALFAGSVESPKSTGLNYIDFKLSRFDDSEKPVPEIGWNSCIPSENLFFGLDPYKRYYFVHSFAAILNSEKKKNLENDGWKIAKAKYGSEEFIAAVNKNNIFATQFHPEKSGKAGLNVIENFLKQQSPPIPNYSAEEKELLMNDYSNYGLTRRIIACLDVRTNDQGDLVVTKGDQYDVREKSDGKGVRNLGKPVQLAQKYYQQGADEVTFLNITSFRDCPLKDTPMLEVLKQAA...
glutamine metabolic process histidine biosynthetic process cytoplasm glutaminase activity imidazoleglycerol-phosphate synthase activity oxo-acid-lyase activity Saccharomyces cerevisiae 3D-structure Amino-acid biosynthesis Glutamine amidotransferase Histidine biosynthesis Hydrolase Lyase Multifunctional enzyme Referenc...
chromatin remodeling positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to starvation
cytoplasm; cytosol; nucleus
cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding
Saccharomyces cerevisiae
Activator Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger
MTVDHDFNSE
MTVDHDFNSEDILFPIESMSSIQYVENNNPNNINNDVIPYSLDIKNTVLDSADLNDIQNQETSLNLGLPPLSFDSPLPVTETIPSTTDNSLHLKADSNKNRDARTIENDSEIKSTNNASGSGANQYTTLTSPYPMNDILYNMNNPLQSPSPSSVPQNPTINPPINTASNETNLSPQTSNGNETLISPRAQQHTSIKDNRLSLPNGANSNLFIDTNPNNLNEKLRNQLNSDTNSYSNSISNSNSNSTGNLNSSYFNSLNIDSMLDDYVSSDLLLNDDDDDTNLSRRRFSDVITNQFPSMTNSRNSISHSLDLWNHPKINPS...
chromatin remodeling positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II response to starvation cytoplasm; cytosol; nucleus cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding S...
aromatic compound catabolic process cellular response to oxidative stress cinnamic acid catabolic process
mitochondrion
carboxy-lyase activity flavin prenyltransferase activity mRNA binding
Saccharomyces cerevisiae
Flavoprotein FMN Mitochondrion Prenyltransferase Reference proteome RNA-binding Transferase Transit peptide
MLLFPRRTNI
MLLFPRRTNIAFFKTTGIFANFPLLGRTITTSPSFLTHKLSKEVTRASTSPPRPKRIVVAITGATGVALGIRLLQVLKELSVETHLVISKWGAATMKYETDWEPHDVAALATKTYSVRDVSACISSGSFQHDGMIVVPCSMKSLAAIRIGFTEDLITRAADVSIKENRKLLLVTRETPLSSIHLENMLSLCRAGVIIFPPVPAFYTRPKSLHDLLEQSVGRILDCFGIHADTFPRWEGIKSK
aromatic compound catabolic process cellular response to oxidative stress cinnamic acid catabolic process mitochondrion carboxy-lyase activity flavin prenyltransferase activity mRNA binding Saccharomyces cerevisiae Flavoprotein FMN Mitochondrion Prenyltransferase Reference proteome RNA-binding Transferase Transit pept...
cytoplasm protein quality control by the ubiquitin-proteasome system DNA replication termination ER-associated misfolded protein catabolic process mitochondria-associated ubiquitin-dependent protein catabolic process mitotic spindle disassembly mRNA transport nonfunctional rRNA decay positive regulation of protein loca...
Cdc48p-Npl4p-Vms1p AAA ATPase complex; cytoplasm; Doa10p ubiquitin ligase complex; Hrd1p ubiquitin ligase ERAD-L complex; nuclear membrane; nuclear outer membrane-endoplasmic reticulum membrane network; nucleus; perinuclear region of cytoplasm; replisome; RQC complex; VCP-NPL4-UFD1 AAA ATPase complex
ubiquitin binding ubiquitin protein ligase binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Endoplasmic reticulum Membrane mRNA transport Nucleus Protein transport Reference proteome Translocation Transport
MLIRFRSKNG
MLIRFRSKNGTHRVSCQENDLFGTVIEKLVGNLDPNADVDTFTVCEKPGQGIHAVSELADRTVMDLGLKHGDMLILNYSDKPANEKDGVNVEIGSVGIDSKGIRQHRYGPLRIKELAVDEELEKEDGLIPRQKSKLCKHGDRGMCEYCSPLPPWDKEYHEKNKIKHISFHSYLKKLNENANKKENGSSYISPLSEPDFRINKRCHNGHEPWPRGICSKCQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFGYMYGSYSKYDNTPLGIKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQIDRQAQEMGLS...
cytoplasm protein quality control by the ubiquitin-proteasome system DNA replication termination ER-associated misfolded protein catabolic process mitochondria-associated ubiquitin-dependent protein catabolic process mitotic spindle disassembly mRNA transport nonfunctional rRNA decay positive regulation of protein loca...
chemotaxis complement receptor mediated signaling pathway G protein-coupled receptor signaling pathway inflammatory response phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration
cytoplasm; plasma membrane
complement receptor activity G protein-coupled receptor activity G protein-coupled receptor binding N-formyl peptide receptor activity RAGE receptor binding scavenger receptor binding
Mus musculus
Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix
MDTNMSLLMN
MDTNMSLLMNKSAVNLMNVSGSTQSVSAGYIVLDVFSYLIFAVTFVLGVLGNGLVIWVAGFRMKHTVTTISYLNLAIADFCFTSTLPFYIASMVMGGHWPFGWFMCKFIYTVIDINLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLAKKVIIVPWICAFLLTLPVIIRLTTVPNSRLGPGKTACTFDFSPWTKDPVEKRKVAVTMLTVRGIIRFIIGFSTPMSIVAICYGLITTKIHRQGLIKSSRPLRVLSFVVAAFFLCWCPFQVVALISTIQVRERLKNMTPGIVTALKITSPLAFFNSCLNPMLYVFMGQDFR...
chemotaxis complement receptor mediated signaling pathway G protein-coupled receptor signaling pathway inflammatory response phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration cytoplasm; plasma membrane complement receptor activity G protei...
protein N-linked glycosylation protein N-linked glycosylation via asparagine
endoplasmic reticulum; endoplasmic reticulum membrane; nuclear envelope; oligosaccharyltransferase complex
glycosyltransferase activity
Saccharomyces cerevisiae
3D-structure Direct protein sequencing Endoplasmic reticulum Glycoprotein Membrane Reference proteome Signal Transmembrane Transmembrane helix
MRTDWNFFFC
MRTDWNFFFCILLQAIFVVGTQTSRTLVLYDQSTEPLEEYSVYLKDLEQRNYKLEYLDINSTSTTVDLYDKEQRLFDNIIVFPTKGGKNLARQIPVKQLIKFFENEGNILCMSSPGAVPNTIRLFLNELGIYPSPKGHVIRDYFSPSSEELVVSSNHLLNKYVYNARKSEDFVFGESSAALLENREQIVPILNAPRTSFTESKGKCNSWTSGSQGFLVVGFQNLNNARLVWIGSSDFLKNKNQDSNQEFAKELLKWTFNEKSVIKSVHAVHSHADGTSYDEEPYKIKDKVIYSVGFSEWNGEEWLPHIADDIQFELRQVD...
protein N-linked glycosylation protein N-linked glycosylation via asparagine endoplasmic reticulum; endoplasmic reticulum membrane; nuclear envelope; oligosaccharyltransferase complex glycosyltransferase activity Saccharomyces cerevisiae 3D-structure Direct protein sequencing Endoplasmic reticulum Glycoprotein Membran...
ER-associated misfolded protein catabolic process fungal-type cell wall biogenesis protein exit from endoplasmic reticulum protein O-linked mannosylation regulation of endoplasmic reticulum unfolded protein response
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex; dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex; endoplasmic reticulum; endoplasmic reticulum membrane
dolichyl-phosphate-mannose-protein mannosyltransferase activity
Saccharomyces cerevisiae
3D-structure Acetylation Direct protein sequencing Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Reference proteome Repeat Transferase Transmembrane Transmembrane helix
MSEEKTYKRV
MSEEKTYKRVEQDDPVPELDIKQGPVRPFIVTDPSAELASLRTMVTLKEKLLVACLAVFTAVIRLHGLAWPDSVVFDEVHFGGFASQYIRGTYFMDVHPPLAKMLYAGVASLGGFQGDFDFENIGDSFPSTTPYVLMRFFSASLGALTVILMYMTLRYSGVRMWVALMSAICFAVENSYVTISRYILLDAPLMFFIAAAVYSFKKYEMYPANSLNAYKSLLATGIALGMASSSKWVGLFTVTWVGLLCIWRLWFMIGDLTKSSKSIFKVAFAKLAFLLGVPFALYLVFFYIHFQSLTLDGDGASFFSPEFRSTLKNNKIP...
ER-associated misfolded protein catabolic process fungal-type cell wall biogenesis protein exit from endoplasmic reticulum protein O-linked mannosylation regulation of endoplasmic reticulum unfolded protein response dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex; dolichyl-phosphate-man...
nucleosome assembly
chromosome, telomeric region; cytosol; nucleoplasm; nucleosome; nucleus
DNA binding protein heterodimerization activity structural constituent of chromatin
Homo sapiens
3D-structure Acetylation ADP-ribosylation Chromosome DNA-binding Glycoprotein Hydroxylation Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation
MPEPSKSAPA
MPEPSKSAPAPKKGSKKAITKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
nucleosome assembly chromosome, telomeric region; cytosol; nucleoplasm; nucleosome; nucleus DNA binding protein heterodimerization activity structural constituent of chromatin Homo sapiens 3D-structure Acetylation ADP-ribosylation Chromosome DNA-binding Glycoprotein Hydroxylation Isopeptide bond Methylation Nucleosome ...
cell cycle cell division cellular hyperosmotic response cellular response to osmotic stress MAPK cascade p38MAPK cascade phosphorylation positive regulation of G2/M transition of mitotic cell cycle
cytoplasm; cytosol; Mcs4 RR-MAPKKK complex; nucleus
ATP binding MAP kinase kinase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity
Schizosaccharomyces pombe
ATP-binding Cell cycle Cell division Kinase Mitosis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase
MSSPNNQPLS
MSSPNNQPLSCSLRQLSISPTAPPGDVGTPGSLLSLSSSSSSNTDSSGSSLGSLSLNSNSSGSDNDSKVSSPSREIPSDPPLPRAVPTVRLGRSTSSRSRNSLNLDMKDPSEKPRRSLPTAAGQNNIGSPPTPPGPFPGGLSTDIQEKLKAFHASRSKSMPEVVNKISSPTTPIVGMGQRGSYPLPNSQLAGRLSNSPVKSPNMPESGLAKSLAAARNPLLNRPTSFNRQTRIRRAPPGKLDLSNSNPTSPVSPSSMASRRGLNIPPTLKQAVSETPFSTFSDILDAKSGTLNFKNKAVLNSEGVNFSSGSSFRINMSEI...
cell cycle cell division cellular hyperosmotic response cellular response to osmotic stress MAPK cascade p38MAPK cascade phosphorylation positive regulation of G2/M transition of mitotic cell cycle cytoplasm; cytosol; Mcs4 RR-MAPKKK complex; nucleus ATP binding MAP kinase kinase activity protein kinase activity protein...
attachment of mitotic spindle microtubules to kinetochore cell division chromosome segregation kinetochore organization meiotic chromosome segregation mitotic spindle organization
condensed chromosome, centromeric region; kinetochore; Ndc80 complex; nucleus; spindle microtubule; spindle pole body
protein-containing complex binding
Saccharomyces cerevisiae
3D-structure Cell cycle Cell division Centromere Chromosome Coiled coil Kinetochore Mitosis Nucleus Reference proteome
MSRNQDVFPI
MSRNQDVFPILDLQELVICLQSCDFALATQENISRPTSDYMVTLYKQIIENFMGISVESLLNSSNQETGDGHLQEENENIYLDTLNVLVLNKICFKFFENIGVQDFNMTDLYKPEAQRTQRLLSAVVNYARFREERMFDCNSFILQMESLLGQLRSKFDDYNLIQQQLKQYEDVDGDNIPDEQELQKLEEQNKELEIQLKKLTKIQETLSIDYNDYKISKQSIFKDLEALSFQIVELESNRDKLIKISNTDMEELSEGIKELNDLLIQRKKTLDDLTAQQKNLQDTVTTFETIISELYDVLRIISSEVQESNRTETELVG...
attachment of mitotic spindle microtubules to kinetochore cell division chromosome segregation kinetochore organization meiotic chromosome segregation mitotic spindle organization condensed chromosome, centromeric region; kinetochore; Ndc80 complex; nucleus; spindle microtubule; spindle pole body protein-containing com...
cellular response to interferon-alpha cellular response to interferon-beta cytokine-mediated signaling pathway defense response to virus gene expression positive regulation of cellular respiration positive regulation of DNA-templated transcription positive regulation of interferon-beta production positive regulation of...
late endosome; lysosome; plasma membrane
cytokine binding interferon receptor activity JAK pathway signal transduction adaptor activity type I interferon binding type I interferon receptor activity
Mus musculus
3D-structure Cell membrane Disulfide bond Endosome Glycoprotein Isopeptide bond Lysosome Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation
MLAVVGAAAL
MLAVVGAAALVLVAGAPWVLPSAAGGENLKPPENIDVYIIDDNYTLKWSSHGESMGSVTFSAEYRTKDEAKWLKVPECQHTTTTKCEFSLLDTNVYIKTQFRVRAEEGNSTSSWNEVDPFIPFYTAHMSPPEVRLEAEDKAILVHISPPGQDGNMWALEKPSFSYTIRIWQKSSSDKKTINSTYYVEKIPELLPETTYCLEVKAIHPSLKKHSNYSTVQCISTTVANKMPVPGNLQVDAQGKSYVLKWDYIASADVLFRAQWLPGYSKSSSGSRSDKWKPIPTCANVQTTHCVFSQDTVYTGTFFLHVQASEGNHTSFWS...
cellular response to interferon-alpha cellular response to interferon-beta cytokine-mediated signaling pathway defense response to virus gene expression positive regulation of cellular respiration positive regulation of DNA-templated transcription positive regulation of interferon-beta production positive regulation of...
alpha-linolenic acid metabolic process fatty acid beta-oxidation fatty acid elongation fatty acid homeostasis linoleic acid metabolic process long-chain fatty acid catabolic process long-chain fatty acid import into peroxisome myelin maintenance negative regulation of cytokine production involved in inflammatory respon...
cytoplasm; cytosol; endoplasmic reticulum membrane; lysosomal membrane; membrane; mitochondrial membrane; perinuclear region of cytoplasm; peroxisomal membrane; peroxisome
ABC-type fatty-acyl-CoA transporter activity acyl-CoA hydrolase activity ADP binding ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity enzyme binding identical protein binding long-chain fatty acid transporter activity protein heterodimerization activity protein homodimerization acti...
Homo sapiens
3D-structure ATP-binding Disease variant Endoplasmic reticulum Glycoprotein Hydrolase Lysosome Membrane Mitochondrion Nucleotide-binding Peroxisome Phosphoprotein Reference proteome Translocase Transmembrane Transmembrane helix Transport
MPVLSRPRPW
MPVLSRPRPWRGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAPAGEPTQEASGVAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELALLQRSYQDLASQINLI...
alpha-linolenic acid metabolic process fatty acid beta-oxidation fatty acid elongation fatty acid homeostasis linoleic acid metabolic process long-chain fatty acid catabolic process long-chain fatty acid import into peroxisome myelin maintenance negative regulation of cytokine production involved in inflammatory respon...
carbohydrate metabolic process mannose trimming involved in glycoprotein ERAD pathway protein glycosylation protein targeting to ER ubiquitin-dependent ERAD pathway
cytoplasmic vesicle; cytosol; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; extracellular exosome; Golgi apparatus; Golgi membrane; membrane
calcium ion binding mannosidase activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
Homo sapiens
Alternative splicing Calcium Disulfide bond Glycoprotein Glycosidase Golgi apparatus Hydrolase Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix
MPVGGLLPLF
MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHTPS...
carbohydrate metabolic process mannose trimming involved in glycoprotein ERAD pathway protein glycosylation protein targeting to ER ubiquitin-dependent ERAD pathway cytoplasmic vesicle; cytosol; endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; extracellular exosome; Golgi apparatus; Golgi me...
mRNA catabolic process negative regulation of translational initiation regulation of bacterial-type flagellum assembly regulation of carbohydrate metabolic process
cytosol
mRNA 5'-UTR binding
Bacillus subtilis
3D-structure Cytoplasm Reference proteome Repressor RNA-binding Translation regulation
MLVLSRKINE
MLVLSRKINEAIQIGADIEVKVIAVEGDQVKLGIDAPKHIDIHRKEIYLTIQEENNRAAALSSDVISALSSQKK
mRNA catabolic process negative regulation of translational initiation regulation of bacterial-type flagellum assembly regulation of carbohydrate metabolic process cytosol mRNA 5'-UTR binding Bacillus subtilis 3D-structure Cytoplasm Reference proteome Repressor RNA-binding Translation regulation MLVLSRKINE MLVLSRKINEAI...
anaerobic respiration Mo-molybdopterin cofactor biosynthetic process nitrate assimilation
nitrate reductase complex; outer membrane-bounded periplasmic space; periplasmic space
4 iron, 4 sulfur cluster binding electron transfer activity iron ion binding molybdenum ion binding molybdopterin cofactor binding nitrate reductase (cytochrome) activity nitrate reductase activity
Escherichia coli
3D-structure 4Fe-4S Direct protein sequencing Electron transport Iron Iron-sulfur Metal-binding Molybdenum Nitrate assimilation Oxidoreductase Periplasm Reference proteome Signal Transport
MKLSRRSFMK
MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLLRMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAASKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAEMHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYIIQNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDA...
anaerobic respiration Mo-molybdopterin cofactor biosynthetic process nitrate assimilation nitrate reductase complex; outer membrane-bounded periplasmic space; periplasmic space 4 iron, 4 sulfur cluster binding electron transfer activity iron ion binding molybdenum ion binding molybdopterin cofactor binding nitrate redu...
endoplasmic reticulum to Golgi vesicle-mediated transport maintenance of protein localization in endoplasmic reticulum protein retention in ER lumen protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
cis-Golgi network; COPI-coated vesicle membrane; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane; membrane; transport vesicle
ER retention sequence binding KDEL sequence binding
Homo sapiens
Alternative splicing Cytoplasmic vesicle Disease variant Endoplasmic reticulum ER-Golgi transport Golgi apparatus Membrane Osteogenesis imperfecta Protein transport Receptor Reference proteome Transmembrane Transmembrane helix Transport
MNIFRLTGDL
MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA
endoplasmic reticulum to Golgi vesicle-mediated transport maintenance of protein localization in endoplasmic reticulum protein retention in ER lumen protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum cis-Golgi network; COPI-coated vesicle membrane; endoplasmic reticulum; endoplasmic...
chromosome segregation female meiosis chromosome segregation meiotic spindle assembly checkpoint signaling mitotic spindle assembly checkpoint signaling mitotic spindle organization phosphorylation positive regulation of cell population proliferation protein localization to kinetochore protein localization to meiotic s...
cytoplasm; kinetochore; membrane; nucleus; spindle
ATP binding identical protein binding kinetochore binding protein serine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity
Homo sapiens
3D-structure Acetylation Alternative splicing ATP-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase
MESEDLSGRE
MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQTSRSECRDLVVPGSKPSGND...
chromosome segregation female meiosis chromosome segregation meiotic spindle assembly checkpoint signaling mitotic spindle assembly checkpoint signaling mitotic spindle organization phosphorylation positive regulation of cell population proliferation protein localization to kinetochore protein localization to meiotic s...
DNA replication DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation regulation of DNA-templated DNA replication initiation
chromosome, telomeric region; CMG complex; MCM complex; membrane; nucleoplasm; nucleus
ATP binding ATP hydrolysis activity DNA helicase activity single-stranded DNA binding
Homo sapiens
3D-structure Acetylation ATP-binding Cell cycle Chromosome DNA replication DNA-binding Helicase Hydrolase Isopeptide bond Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation
MSSPASTPSR
MSSPASTPSRRGSRRGRATPAQTPRSEDARSSPSQRRRGEDSTSTGELQPMPTSPGVDLQSPAAQDVLFSSPPQMHSSAIPLDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVRQRPDLGSAQKGLQVDLQSDGAAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRG...
DNA replication DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication mitotic DNA replication initiation regulation of DNA-templated DNA replication initiation chromosome, telomeric region; CMG complex; MCM complex; membrane;...
cell cycle DNA replication DNA replication initiation DNA unwinding involved in DNA replication double-strand break repair via break-induced replication regulation of DNA-templated DNA replication initiation
chromosome, telomeric region; CMG complex; MCM complex; membrane; nucleoplasm; nucleus
ATP binding ATP hydrolysis activity DNA replication origin binding helicase activity single-stranded DNA binding
Homo sapiens
3D-structure Acetylation ATP-binding Cell cycle Chromosome Disease variant DNA replication DNA-binding Dwarfism Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome
MSGFDDPGIF
MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQVDTDGSGRSFAGAVSPQEEE...
cell cycle DNA replication DNA replication initiation DNA unwinding involved in DNA replication double-strand break repair via break-induced replication regulation of DNA-templated DNA replication initiation chromosome, telomeric region; CMG complex; MCM complex; membrane; nucleoplasm; nucleus ATP binding ATP hydrolysi...
cell cycle cell population proliferation cellular response to xenobiotic stimulus DNA damage response DNA replication DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication regulation of DNA-template...
chromatin; chromosome, telomeric region; CMG complex; cytosol; MCM complex; membrane; nucleoplasm; nucleus
ATP binding ATP hydrolysis activity DNA helicase activity single-stranded DNA binding
Homo sapiens
3D-structure Acetylation Alternative splicing ATP-binding Cell cycle Chromosome Direct protein sequencing DNA replication DNA-binding Glycoprotein Helicase Hydrolase Isopeptide bond Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ubl conjugation
MALKDYALEK
MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELT...
cell cycle cell population proliferation cellular response to xenobiotic stimulus DNA damage response DNA replication DNA replication initiation DNA strand elongation involved in DNA replication DNA unwinding involved in DNA replication double-strand break repair via break-induced replication regulation of DNA-template...
activation of protein kinase B activity angiogenesis branch elongation involved in ureteric bud branching cell differentiation cellular response to heat epithelial cell proliferation fibroblast growth factor receptor signaling pathway lung development mesonephric epithelium development organ induction positive regulati...
cell cortex; cytosol; extracellular matrix; extracellular region; extracellular space; nucleoplasm
fibroblast growth factor receptor binding growth factor activity heparin binding integrin binding S100 protein binding
Mesocricetus auratus
Acetylation Angiogenesis Cytoplasm Developmental protein Differentiation Growth factor Heparin-binding Mitogen Nucleus Phosphoprotein Reference proteome Secreted
MAEGEITTFS
MAEGEITTFSALTERFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESAGEVYIKGTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYTSKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD
activation of protein kinase B activity angiogenesis branch elongation involved in ureteric bud branching cell differentiation cellular response to heat epithelial cell proliferation fibroblast growth factor receptor signaling pathway lung development mesonephric epithelium development organ induction positive regulati...
negative chemotaxis negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation platelet-derived growth factor receptor signaling pathway positive regulation of cell division positive regulation of cell migration positive regulation of cell population proliferation positi...
cell surface; extracellular space; membrane
collagen binding growth factor activity platelet-derived growth factor receptor binding protein homodimerization activity
Oryctolagus cuniculus
Alternative splicing Developmental protein Disulfide bond Glycoprotein Growth factor Mitogen Reference proteome Secreted Signal
MRTWACLLLL
MRTWACLLLLGCGYLAHVLAEEPGIPRDVLDRLARSQIHSIRDLQRLLEIDSVGAEDAPEPSLRAPGVHTARHVAEKPPAPVPVRRKRTIEEAIPAICKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACAASSAGPEHREEEAGRRRESGKKRKRKRLRPT
negative chemotaxis negative regulation of phosphatidylinositol biosynthetic process negative regulation of platelet activation platelet-derived growth factor receptor signaling pathway positive regulation of cell division positive regulation of cell migration positive regulation of cell population proliferation positi...
cellular response to leptomycin B nucleocytoplasmic transport positive regulation of mitotic centrosome separation positive regulation of neuron projection development spindle organization
axon cytoplasm; centrosome; cytoplasm; cytosol; nuclear pore; plasma membrane bounded cell projection cytoplasm
GDP-dissociation inhibitor activity GTPase activator activity
Mus musculus
Acetylation GTPase activation Phosphoprotein Reference proteome
MAAAKDSHED
MAAAKDSHEDHDTSTENADESNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKLLKHKEKGTIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLAIRFLNAENAQKFKTKFEECRKEIEEREKKGPGKNDNAEKVAEKLEALSVREAREEAEEKSEEKQ
cellular response to leptomycin B nucleocytoplasmic transport positive regulation of mitotic centrosome separation positive regulation of neuron projection development spindle organization axon cytoplasm; centrosome; cytoplasm; cytosol; nuclear pore; plasma membrane bounded cell projection cytoplasm GDP-dissociation in...
adenylate cyclase-modulating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development chemotaxis chemotaxis to folate MAPK cascade protein localization regulation of macropinocytosis sporulation resulting in formation of a cellular spore
heterotrimeric G-protein complex; phagocytic vesicle; plasma membrane
G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding mitogen-activated protein kinase binding protein kinase activator activity protein kinase regulator activity
Dictyostelium discoideum
GTP-binding Magnesium Metal-binding Nucleotide-binding Reference proteome Transducer
MRFKCFGSEE
MRFKCFGSEETEQSSKIDKSIETDRRKLRKDVKLLLLGPGESGKSTIFKQMKIIQEDGGYSVEELLEYRAFVYSNCISQMEALLTASAKLNIELEVENKQRAANVLRRTIGNEPWLLLAADIKHLWEDKGIKETYAQKDKHFQLNDSAAYFFDNIDRYMREDFVPNEQDVLRCRVRTTGIQESEFTFDKIRLKIVDVGGQRSQRRKWIHCFDCVTAVIFVAAMSDYDQVLREDESVNRTRESLALFKEIVNCDYFKETPIVLFLNKKDLFKEKLKRVPLQSCFSDYTGPNKYKDAAMFIQSQYLAQGPSPRTIYTHATCA...
adenylate cyclase-modulating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development chemotaxis chemotaxis to folate MAPK cascade protein localization regulation of macropinocytosis sporulation resulting in formation of a cellular spore heterotrimeric G-protein complex; phagocytic vesi...
adenylate cyclase-modulating G protein-coupled receptor signaling pathway chemotaxis to folate G protein-coupled receptor signaling pathway regulation of aggregate size involved in sorocarp development response to bacterium sorocarp development
heterotrimeric G-protein complex
G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding
Dictyostelium discoideum
GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Palmitate Reference proteome Transducer
MGCILTIEAK
MGCILTIEAKKSRDIDYQLRKEEGSKNETKLLLLGPGESGKSTIFKQMKIIQDDGGFSIDERLEYRYIIYGNCISQMKVLVTAAISQDLKPNNPDNETRFEKFSKISPGGNSWTLEIAEDIKQLWSDDSIQNIYRMKDKFYQLNDSAAYFFDNIGRFANENYVPTQDDVLRSRVRTTGIQEAHFKFINIEFRMLDVGGQRSERRKWIHCFDSVTAVIFCVALSEYDQTLREEESQNRMKESLMLFDEIVNSHWFRNTAFIIFFNKVDLFREKIAKIDLGDYFPAYTGGLSFDNSTQFIKKMFLDLSTGNQRIFAHFTCAI...
adenylate cyclase-modulating G protein-coupled receptor signaling pathway chemotaxis to folate G protein-coupled receptor signaling pathway regulation of aggregate size involved in sorocarp development response to bacterium sorocarp development heterotrimeric G-protein complex G protein-coupled receptor binding G-prote...
adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled chemorepellent receptor signaling pathway negative regulation of asexual reproduction positive regulation of cell-cell adhesion positive regulation of cell-substrate adhesion positive regulation of sporulation regulation of cell...
heterotrimeric G-protein complex; plasma membrane
G protein-coupled chemorepellent receptor activity G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding
Dictyostelium discoideum
GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Palmitate Reference proteome Transducer
MGCYQSRVQV
MGCYQSRVQVEDKTNEQLDKYLVQAGKEGLLDFRILLLGAGESGKSTVVKQLKSIYKIQVDDDELHSYAVNIHKNTVLCMQVLLEAGETLGIELTDPETKKRAINVKSFQFEPEVKQMPVSIGLDIEELWRDEDIQKIWDRRSEYWFLDATPYYFENIQRFLDDDFVPTEEDCIMTRVRTTGISVTEFDEGPVHFRVVDVGGQRNERKKWIHCFDDVKALLFVVNLAGYDQVMFEDPSQNRMQESLTLFGQICNNPIFSETPTFLVLNKKDLFEQMIQKTDLSKCFPDYKGGSDVKTALEFIQMKYQQKIQESNKPLHTF...
adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled chemorepellent receptor signaling pathway negative regulation of asexual reproduction positive regulation of cell-cell adhesion positive regulation of cell-substrate adhesion positive regulation of sporulation regulation of cell...
phototransduction regulation of calcium ion transport visual perception
dendrite; membrane; perikaryon; photoreceptor inner segment; photoreceptor outer segment
calcium ion binding
Mus musculus
Calcium Cell projection Disulfide bond Lipoprotein Membrane Metal-binding Myristate Oxidation Redox-active center Reference proteome Repeat Sensory transduction Vision
MGNSKSGALS
MGNSKSGALSKEILEELQLNTKFTEEELSAWYQSFLKECPSGRITRQEFESIYSKFFPDSDPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTTAGKPTQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMIKPEDVKLLPDDENTPEKRAEKIWAFFGKKEDDKLTEEEFIEGTLANKEILRLIQFEPQKVKERIKEKKQ
phototransduction regulation of calcium ion transport visual perception dendrite; membrane; perikaryon; photoreceptor inner segment; photoreceptor outer segment calcium ion binding Mus musculus Calcium Cell projection Disulfide bond Lipoprotein Membrane Metal-binding Myristate Oxidation Redox-active center Reference pr...
nuclear pore organization nucleocytoplasmic transport poly(A)+ mRNA export from nucleus protein import into nucleus ribosomal large subunit export from nucleus
nuclear envelope; nuclear membrane; nuclear pore; nuclear pore linkers; nuclear pore nuclear basket
structural constituent of nuclear pore
Saccharomyces cerevisiae
3D-structure Direct protein sequencing Membrane mRNA transport Nuclear pore complex Nucleus Protein transport Reference proteome Translocation Transport
MLETLRGNKL
MLETLRGNKLHSGTSKGANKKLNELLESSDNLPSASSELGSIQVSINELRRRVFQLRSKNKASKDYTKAHYLLANSGLSFEDVDAFIKDLQTNQFLEPNPPKIIESEELEFYIRTKKEENILMSIEQLLNGATKDFDNFINHNLNLDWAQHKNEVMKNFGILIQDKKTVDHKKSISSLDPKLPSWGNKGNNILNSNESRLNVNENNILREKFENYARIVFQFNNSRQANGNFDIANEFISILSSANGTRNAQLLESWKILESMKSKDINIVEVGKQYLEQQFLQYTDNLYKKNMNEGLATNVNKIKSFIDTKLKKADKSW...
nuclear pore organization nucleocytoplasmic transport poly(A)+ mRNA export from nucleus protein import into nucleus ribosomal large subunit export from nucleus nuclear envelope; nuclear membrane; nuclear pore; nuclear pore linkers; nuclear pore nuclear basket structural constituent of nuclear pore Saccharomyces cerevis...
actin filament depolymerization actin filament organization cell volume homeostasis cellular response to copper ion cellular response to mercury ion cellular response to water deprivation female pregnancy glycerol transmembrane transport hyperosmotic response metanephric collecting duct development positive regulation ...
apical plasma membrane; basolateral plasma membrane; clathrin-coated vesicle; cytoplasm; cytoplasmic vesicle; cytoplasmic vesicle membrane; early endosome; exocytic vesicle; extracellular exosome; lumenal side of membrane; membrane; perinuclear region of cytoplasm; plasma membrane; protein-containing complex; recycling...
actin binding glycerol transmembrane transporter activity PDZ domain binding water channel activity water transmembrane transporter activity
Rattus norvegicus
Cell membrane Cytoplasmic vesicle Glycoprotein Golgi apparatus Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport
MWELRSIAFS
MWELRSIAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGILVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRGDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAIIGSLLYNYLLFPSAKSLQERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGSKA
actin filament depolymerization actin filament organization cell volume homeostasis cellular response to copper ion cellular response to mercury ion cellular response to water deprivation female pregnancy glycerol transmembrane transport hyperosmotic response metanephric collecting duct development positive regulation ...
axon guidance axonal fasciculation behavioral response to ethanol Bolwig's organ morphogenesis cell morphogenesis involved in neuron differentiation dendrite self-avoidance homophilic cell adhesion via plasma membrane adhesion molecules imaginal disc-derived male genitalia morphogenesis learning or memory motor neuron ...
apical plasma membrane; axon; cell projection; cytoplasm; growth cone; leading edge membrane; muscle cell postsynaptic specialization; neuromuscular junction; neuron projection; plasma membrane; postsynaptic membrane; presynaptic active zone; presynaptic membrane; presynaptic periactive zone; side of membrane; type I t...
cell-cell adhesion mediator activity
Drosophila melanogaster
Alternative splicing Cell adhesion Cell membrane Developmental protein Differentiation Disulfide bond Glycoprotein GPI-anchor Immunoglobulin domain Lipoprotein Membrane Neurogenesis Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix
MGELPPNSVG
MGELPPNSVGVFLALLLCSCSLIELTRAQSPILEIYPKQEVQRKPVGKPLILTCRPTVPEPSLVADLQWKDNRNNTILPKPNGRNQPPMYTETLPGESLALMITSLSVEMGGKYYCTASYANTEILEKGVTIKTYVAITWTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNVL...
axon guidance axonal fasciculation behavioral response to ethanol Bolwig's organ morphogenesis cell morphogenesis involved in neuron differentiation dendrite self-avoidance homophilic cell adhesion via plasma membrane adhesion molecules imaginal disc-derived male genitalia morphogenesis learning or memory motor neuron ...
DNA-templated transcription initiation nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA catabolic process, exonucleolytic positive regulation of nuclear-transcribed mRNA poly(A) tail shortening positive regulation of translational initiation RNA-templated transcription ...
cytoplasm; nucleus; P-body; RNA polymerase II, core complex; RPB4-RPB7 complex
single-stranded DNA binding single-stranded RNA binding translation initiation factor binding
Saccharomyces cerevisiae
3D-structure Cytoplasm DNA-directed RNA polymerase Nucleus Reference proteome Transcription
MFFIKDLSLN
MFFIKDLSLNITLHPSFFGPRMKQYLKTKLLEEVEGSCTGKFGYILCVLDYDNIDIQRGRILPTDGSAEFNVKYRAVVFKPFKGEVVDGTVVSCSQHGFEVQVGPMKVFVTKHLMPQDLTFNAGSNPPSYQSSEDVITIKSRIRVKIEGCISQVSSIHAIGSIKEDYLGAI
DNA-templated transcription initiation nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA catabolic process, exonucleolytic positive regulation of nuclear-transcribed mRNA poly(A) tail shortening positive regulation of translational initiation RNA-templated transcription ...
CTP biosynthetic process GTP biosynthetic process nucleoside triphosphate biosynthetic process phosphorylation response to bacterium UTP biosynthetic process
extracellular matrix; mitochondrial intermembrane space; mitochondrion; phagocytic vesicle
ATP binding metal ion binding nucleoside diphosphate kinase activity
Dictyostelium discoideum
ATP-binding Direct protein sequencing Kinase Magnesium Metal-binding Mitochondrion Nucleotide metabolism Nucleotide-binding Phosphoprotein Reference proteome Transferase Transit peptide
MFSRFARAFP
MFSRFARAFPKILASGASQRTFATVQKAFANPTSKKLIVGSSLLIGSAFATTSFVACENKSVPLVGLPGTNQERSFIAIKVSSTQRRLIGEIIARFEKKGFKLVGIKILVPTPEHAAKHYEDLNKKPFFNGLVKFFSSGAVVAMVFEGKDVVRTGRVLIGATDPSQSAPGTIRFDLCIETGRNIIHGSDSNESAAHEIALWFKEDEIANWVSTNPVYEKM
CTP biosynthetic process GTP biosynthetic process nucleoside triphosphate biosynthetic process phosphorylation response to bacterium UTP biosynthetic process extracellular matrix; mitochondrial intermembrane space; mitochondrion; phagocytic vesicle ATP binding metal ion binding nucleoside diphosphate kinase activity Di...
antibacterial humoral response defense response to Gram-positive bacterium
extracellular region; extracellular space
nucleic acid binding ribonuclease A activity RNA nuclease activity
Homo sapiens
3D-structure Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Endonuclease Hydrolase Nuclease Pyrrolidone carboxylic acid Reference proteome Secreted Signal
MALQRTHSLL
MALQRTHSLLLLLLLTLLGLGLVQPSYGQDGMYQRFLRQHVHPEETGGSDRYCNLMMQRRKMTLYHCKRFNTFIHEDIWNIRSICSTTNIQCKNGKMNCHEGVVKVTDCRDTGSSRAPNCRYRAIASTRRVVIACEGNPQVPVHFDG
antibacterial humoral response defense response to Gram-positive bacterium extracellular region; extracellular space nucleic acid binding ribonuclease A activity RNA nuclease activity Homo sapiens 3D-structure Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Endonuclease Hydrolase Nuclease Pyrrolidone ...
mannose metabolic process protein modification process sorocarp development
early phagosome; lysosome
alpha-mannosidase activity carbohydrate binding metal ion binding
Dictyostelium discoideum
Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Lysosome Metal-binding Reference proteome Signal Zinc Zymogen
MVIKKLFILI
MVIKKLFILIFCLFLIINEINGKKTKINDIKKSKPKLSSTLLNVHIVAHTHDDVGWLKTVDEYYYGSNMSIAFAGVQYTLDTAITCLLANPERKFIYVEIAFFQRWWDEQSTTMQNIVKGLVESGQLEFINGGYCMNDEATTYYDDTIDQMTLGHQFLWENFGVMPKIGWHIDPFGHSATQARIFGQLGFDAFIIGRMDYQDIEARLENKQMEFMWRSTQSTPENQVFTSVLRAMYCTPDGFNFEQGDDPIQDDPNLFDNNVDSRAEQFTQVALEYATHYRTNNVLIPFGCDFAYLNAQMYYKNIDKLIAHINSNPDKYG...
mannose metabolic process protein modification process sorocarp development early phagosome; lysosome alpha-mannosidase activity carbohydrate binding metal ion binding Dictyostelium discoideum Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Lysosome Metal-binding Reference proteome Signal Zi...
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway c-di-GMP signaling chemotaxis to cAMP culmination involved in sorocarp development establishment of cell polarity regulating cell shape G protein-coupled chemorepellent receptor signaling pathway MAPK cascade negative regulation of gene expr...
cAMP-dependent protein kinase complex; centrosome; cytosol
AMP-activated protein kinase activity ATP binding cAMP-dependent protein kinase activity protein kinase A regulatory subunit binding protein kinase inhibitor activity protein kinase regulator activity protein serine kinase activity
Dictyostelium discoideum
ATP-binding cAMP Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase
MSNSNNNSSS
MSNSNNNSSSGNHNSTTINNPKVNVYSNIPNSTTYTYGSGGGGTLSGNNTNNNNTNNNNNNNNNSSGDNKNHSPVTSATDRLTKMDIEEKWDNKNYEKDEREKSPLFHILASNLNSFGNFKVPSTFSLTPPEPNKQQQPQQQPQQQQPQQQQPQQQQPQQQQQQQPQQQQQPQQQLQQNNQQQQQQLQQQQLQQQLQQQQQQQQQQQQQQQQKQQKQQQQQQQHLHQDGIVNTPSTTQTSTTTTTTTTTTNPHTSGLSLQHAHSSYTPSNVLHSPTHFQSSLPTRLDTNPITTPIRQQQQSQQQLQQQQLQQIPPPTVNS...
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway c-di-GMP signaling chemotaxis to cAMP culmination involved in sorocarp development establishment of cell polarity regulating cell shape G protein-coupled chemorepellent receptor signaling pathway MAPK cascade negative regulation of gene expr...
cell division G1/S transition of mitotic cell cycle phosphorylation regulation of cell cycle regulation of G2/M transition of mitotic cell cycle regulation of gene expression regulation of intermediate filament depolymerization response to organic substance signal transduction
cyclin-dependent protein kinase holoenzyme complex; cytoplasm; nucleus
ATP binding cyclin binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity
Dictyostelium discoideum
ATP-binding Cell cycle Cell division Kinase Mitosis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase
MESDGGLSRY
MESDGGLSRYQKLEKLGEGTYGKVYKAKEKATGRMVALKKIRLEDDGVPSTALREISLLKEVPHPNVVSLFDVLHCQNRLYLVFEYLDQDLKKYMDSVPALCPQLIKSYLYQLLKGLAYSHGHRILHRDLKPQNLLIDRQGALKLADFGLARAVSIPVRVYTHEIVTLWYRAPEVLLGSKSYSVPVDMWSVGCIFGEMLNKKPLFSGDCEIDQIFRIFRVLGTPDDSIWPGVTKLPEYVSTFPNWPGQPYNKIFPRCEPLALDLIAKMLQYEPSKRISAKEALLHPYFGDLDTSFF
cell division G1/S transition of mitotic cell cycle phosphorylation regulation of cell cycle regulation of G2/M transition of mitotic cell cycle regulation of gene expression regulation of intermediate filament depolymerization response to organic substance signal transduction cyclin-dependent protein kinase holoenzyme...
glycogen catabolic process response to ammonium ion response to cAMP response to differentiation-inducing factor 1
cytoplasm
glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity
Dictyostelium discoideum
Allosteric enzyme Carbohydrate metabolism Direct protein sequencing Glycogen metabolism Glycosyltransferase Pyridoxal phosphate Reference proteome Transferase
MEEKRSTNSP
MEEKRSTNSPGFDKPKLNRSGSITSATSHPPRSNSNPKLVAKHQQQLYEESKNKRNQEQQNQQPQQQQQKQTSNQSEDPATQLSSLKFESDKEKEQALLWAFLASYLPEDKGSLQKEFVKHVEYTLAQTKSECTDFSSFQALSYCTRDRLIERWKDTKLFFKQKNVKQVNYMSLEFLLGRSLQNSLSALGLVGKYSDALMDLGFKLEDLYDEERDAGLGNGGLGRLAACFMDSLATCNFPGYGYGLRYKFGMFYQTLVDGEQVELPDYWLNYGSPWEIERLDVSYPINFYGKVSEVEDENGKKVMKWDQGEQMLAVAYDY...
glycogen catabolic process response to ammonium ion response to cAMP response to differentiation-inducing factor 1 cytoplasm glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity Dictyostelium dis...
aggregation involved in sorocarp development asexual reproduction phagocytosis phosphorylation pinocytosis regulation of aggregate size involved in sorocarp development sporulation resulting in formation of a cellular spore vesicle-mediated transport
cytoplasm; mitotic spindle; nucleoplasm; nucleus
ATP binding calmodulin binding cyclin-dependent protein serine/threonine kinase activity protein serine kinase activity
Dictyostelium discoideum
ATP-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase
MEKYSKIEKL
MEKYSKIEKLGEGTYGIVYKAKNRETGEIVALKRIRLDSEDEGVPCTAIREISLLKELKHPNIVRLHDVIHTERKLTLVFEYLDQDLKKYLDECGGEISKPTIKSFMYQLLKGVAFCHDHRVLHRDLKPQNLLINRKGELKLADFGLARAFGIPVRTYSHEVVTLWYRAPDVLMGSRKYSTPIDIWSAGCIFAEMASGRPLFPGSGTSDQLFRIFKILGTPNEESWPSITELPEYKTDFPVHPAHQLSSIVHGLDEKGLNLLSKMLQYDPNQRITAAAALKHPYFDGLEPIN
aggregation involved in sorocarp development asexual reproduction phagocytosis phosphorylation pinocytosis regulation of aggregate size involved in sorocarp development sporulation resulting in formation of a cellular spore vesicle-mediated transport cytoplasm; mitotic spindle; nucleoplasm; nucleus ATP binding calmodul...
anatomical structure morphogenesis cellular response to fatty acid cellular response to lithium ion diacylglycerol metabolic process intracellular signal transduction lipid phosphorylation phosphatidic acid biosynthetic process protein kinase C-activating G protein-coupled receptor signaling pathway regulation of posit...
cytosol; membrane
ATP binding ATP-dependent diacylglycerol kinase activity diacylglycerol binding metal ion binding nucleotide binding protein kinase activity protein serine/threonine kinase activity
Dictyostelium discoideum
ATP-binding Kinase Lipid metabolism Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase Zinc Zinc-finger
MNQLNISHNW
MNQLNISHNWKIKSFTSITFCDHCGSMLWGICTQGFQCSDCNFSAHSHCTNLVTLHCNNNKNNSKPNEKPATITAAAASSSTTTTTTTETSTNTAASTTTTTNNIDIKNKDKTPTTSPFSSPILSSYNNNSGNEFCSNRQHKFHKTSKSITKFCNYCRETTFTISGEPVMCSECRYIAHGHCQTKVPLNCIIPYSSPINTINDGGNVRHHWVEGNLKKSKKCIHCMEPCEKSFSLAHYKCLWCHKYLHSSCFDKHNPICDFGSLSDMILPPSSIRLLSTTATTTNKIEKLIIEEQQPQLSSSPSSPRLNINNNNNNNEII...
anatomical structure morphogenesis cellular response to fatty acid cellular response to lithium ion diacylglycerol metabolic process intracellular signal transduction lipid phosphorylation phosphatidic acid biosynthetic process protein kinase C-activating G protein-coupled receptor signaling pathway regulation of posit...
adult locomotory behavior epidermis development ganglion mother cell fate determination innervation long-term memory mechanoreceptor differentiation memory modulation of chemical synaptic transmission negative regulation of neuron apoptotic process nerve development nerve growth factor signaling pathway neuron projecti...
axon; dendrite; extracellular region; extracellular space; synaptic vesicle
growth factor activity nerve growth factor receptor binding
Homo sapiens
3D-structure Cleavage on pair of basic residues Disulfide bond Glaucoma Glycoprotein Growth factor Reference proteome Secreted Signal
MLPLPSCSLP
MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA
adult locomotory behavior epidermis development ganglion mother cell fate determination innervation long-term memory mechanoreceptor differentiation memory modulation of chemical synaptic transmission negative regulation of neuron apoptotic process nerve development nerve growth factor signaling pathway neuron projecti...
adult locomotory behavior epidermis development ganglion mother cell fate determination innervation long-term memory mechanoreceptor differentiation memory modulation of chemical synaptic transmission negative regulation of neuron apoptotic process negative regulation of programmed cell death nerve development nerve gr...
axon; dendrite; extracellular region; extracellular space; synaptic vesicle
growth factor activity nerve growth factor receptor binding
Rattus norvegicus
Cleavage on pair of basic residues Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal
MLPRHSCSLL
MLPRHSCSLLLFLLLLPSVPMEPQPPSSTLPPFLAPEWDLLSPRVALSRGTPAGPPLLFLLEAGAYGEPAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKAESAGEGGPGVGGGGCRGVDRRHWLSECKAKQSYVRALTADSQGRVGWRWIRIDTACVCTLLSRTGRA
adult locomotory behavior epidermis development ganglion mother cell fate determination innervation long-term memory mechanoreceptor differentiation memory modulation of chemical synaptic transmission negative regulation of neuron apoptotic process negative regulation of programmed cell death nerve development nerve gr...
dephosphorylation regulation of sorocarp development
cytoplasm; plasma membrane
phosphatase activity protein tyrosine phosphatase activity
Dictyostelium discoideum
Cell membrane Cytoplasm Hydrolase Membrane Protein phosphatase Reference proteome
MGSVESSNQM
MGSVESSNQMNGSIENKTNKIDISVLRPLPTRSNSSISLSSSSHSSFSRMGSLGSLPTNSGSSSPYYNNSSFDLVDEERIKSSIYNLKNHIKCIHKIKEEFRLLEESVGPSETSEGDKKHNTSKNRYTNILPVNHTRVQLKKIQDKEGSDYINANYIDGAYPKQFICTQGPLPNTIADFWRMVWENRCRIIVMLSRESENCRIKCDRYWPEQIGGEQFSIYGNGNEVFGTYSVELVEVIQDPEREIITRNIRLTFEGETRDITQYQYEGWPDHNIPDHTQPFRQLLHSITNRQNQIIPSSDRNVPIIVHCSAGVGRTGTF...
dephosphorylation regulation of sorocarp development cytoplasm; plasma membrane phosphatase activity protein tyrosine phosphatase activity Dictyostelium discoideum Cell membrane Cytoplasm Hydrolase Membrane Protein phosphatase Reference proteome MGSVESSNQM MGSVESSNQMNGSIENKTNKIDISVLRPLPTRSNSSISLSSSSHSSFSRMGSLGSLPTNSGSS...
cortical actin cytoskeleton organization filopodium assembly hypotonic response intracellular protein transport phagocytosis positive regulation of phagocytosis Rab protein signal transduction
early endosome; endomembrane system; intracellular organelle; lipid droplet; pathogen-containing vacuole; plasma membrane
GTP binding GTPase activity
Dictyostelium discoideum
Cell membrane GTP-binding Lipoprotein Membrane Nucleotide-binding Phagocytosis Prenylation Protein transport Reference proteome Transport
MTDTEKSFKV
MTDTEKSFKVVLLGEGCVGKTSIVFRYIDNIFNDKHLMTQHAGFFQKHINIGGKRICLTIWDTAGQERFHALGPIYYRGSQGALVVYDITDNDSFIKAKNWIKELKTMLGNDISLCIIGNKCDLEKTRVIPLADAEAYAKSVGAIHYSTSAKLNKGIEELFLDLTRRMILNSSGVVIHSNTNTTGQTTNRSERIPIVPDSDSGNKQPGCCSN
cortical actin cytoskeleton organization filopodium assembly hypotonic response intracellular protein transport phagocytosis positive regulation of phagocytosis Rab protein signal transduction early endosome; endomembrane system; intracellular organelle; lipid droplet; pathogen-containing vacuole; plasma membrane GTP b...
actin filament organization cortical cytoskeleton organization engulfment of apoptotic cell establishment or maintenance of cell polarity mitotic cytokinesis positive regulation of actin filament polymerization Rac protein signal transduction regulation of actin cytoskeleton organization regulation of cell motility reg...
cell cortex; cell leading edge cell cortex; cell projection; cell trailing edge; cytoplasmic vesicle; cytoskeleton; lipid droplet; perinuclear region of cytoplasm; phagocytic cup; phagocytic vesicle; plasma membrane
GTP binding GTPase activity protein kinase binding
Dictyostelium discoideum
Cell membrane GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome
MQAIKCVVVG
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSIISPSSFENVNGKWHPEICHHAPNVPIILVGTKLDMREDKETQDRLKEKKLYPISYEQGLAKMKEINAVKYLECSALTQKGLKTVFDEAIRAVINPPLSKKKKSSGGCNIL
actin filament organization cortical cytoskeleton organization engulfment of apoptotic cell establishment or maintenance of cell polarity mitotic cytokinesis positive regulation of actin filament polymerization Rac protein signal transduction regulation of actin cytoskeleton organization regulation of cell motility reg...
actin filament organization aggregation involved in sorocarp development chemotaxis to folate cortical cytoskeleton organization endocytosis engulfment of apoptotic cell establishment or maintenance of cell polarity mitotic cytokinesis positive regulation of actin filament polymerization Rac protein signal transduction...
cell projection; cytoplasm; cytoplasmic vesicle; cytoskeleton; lamellipodium; plasma membrane; pseudopodium
GTP binding GTPase activity protein kinase binding
Dictyostelium discoideum
Cell membrane GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome
MQAIKCVVVG
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSIVSPASFENVNGKWHPEICHHAPNVPIILVGTKLDMREDRDTQDRLKEKKLYPVSYEQGLSKMKEINAVKYLECSALTQKGLKTVFDEAIRSVINPTLKKKPKSSKGCIIM
actin filament organization aggregation involved in sorocarp development chemotaxis to folate cortical cytoskeleton organization endocytosis engulfment of apoptotic cell establishment or maintenance of cell polarity mitotic cytokinesis positive regulation of actin filament polymerization Rac protein signal transduction...
actin filament organization cortical cytoskeleton organization engulfment of apoptotic cell establishment or maintenance of cell polarity mitotic cytokinesis regulation of actin cytoskeleton organization regulation of cell shape response to bacterium response to imidacloprid sexual reproduction signal transduction smal...
cell projection; cytoplasmic vesicle; cytoskeleton; plasma membrane
GTP binding GTPase activity protein kinase binding
Dictyostelium discoideum
Cell membrane GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome
MQAIKCVVVG
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSIISPSSYENVSGKWGPEVFHHAPNVPIILVGTKMDMREDKETQDRLKEKKLYPVSYEQGLLKMKEINAFKYLECSALTQKGLKTVFDEAIRSVINPPVKKSKSKSGCNIL
actin filament organization cortical cytoskeleton organization engulfment of apoptotic cell establishment or maintenance of cell polarity mitotic cytokinesis regulation of actin cytoskeleton organization regulation of cell shape response to bacterium response to imidacloprid sexual reproduction signal transduction smal...
actin filament organization actin filament polymerization aggregation involved in sorocarp development chemotaxis cortical cytoskeleton organization engulfment of apoptotic cell establishment or maintenance of cell polarity macropinocytosis regulation of actin cytoskeleton organization regulation of cell shape signal t...
cell projection; cytoplasm; cytoplasmic vesicle; cytoskeleton; lipid droplet; plasma membrane
GTP binding GTPase activity protein kinase binding
Dictyostelium discoideum
Cell membrane GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome
MQSIKLVVVG
MQSIKLVVVGDGAVGKTCLLISYTSNSFPTEYVPTVFDNYSANVMVDNKTVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICFAIISQTSYTNVKSKWWPEVTHHCPNCTIILVGTKCDLREDKESLEKLREKHQQPLTFQQGEQMAKEIKAFCYMECSALTQKGLKQVFDEAIKAVIFPDRDKATNKKNSKCSIL
actin filament organization actin filament polymerization aggregation involved in sorocarp development chemotaxis cortical cytoskeleton organization engulfment of apoptotic cell establishment or maintenance of cell polarity macropinocytosis regulation of actin cytoskeleton organization regulation of cell shape signal t...
actin filament organization cell migration chemotaxis cortical cytoskeleton organization engulfment of apoptotic cell establishment of protein localization establishment or maintenance of cell polarity G protein-coupled chemorepellent receptor signaling pathway mitotic cytokinesis phosphatidylinositol 3-kinase/protein ...
cell leading edge; cell projection; cytoplasmic vesicle; cytoskeleton; cytosol; plasma membrane
GTP binding GTPase activity protein domain specific binding protein kinase binding
Dictyostelium discoideum
Cell membrane GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome
MSAAEVIKLV
MSAAEVIKLVVIGDGAVGKTCLLISYANNRFPEDYIPTVFDNYVVNLTAGDRNIELGLWDTAGQEEYDKLRPLSYANANVFLICFSITNPVSFENVYTKWYPEVMHFCPEVPQILVGTKLDTRDDRGVLDKLQQTGHKPITTEQGNDLARRIKAIKYMECSAKTSQNLKQVFDEAIKSVLFIKKKKSKCIVM
actin filament organization cell migration chemotaxis cortical cytoskeleton organization engulfment of apoptotic cell establishment of protein localization establishment or maintenance of cell polarity G protein-coupled chemorepellent receptor signaling pathway mitotic cytokinesis phosphatidylinositol 3-kinase/protein ...
7-methylguanosine mRNA capping mRNA 3'-end processing mRNA export from nucleus mRNA splicing, via spliceosome mRNA transcription by RNA polymerase II nuclear-transcribed mRNA catabolic process nuclear-transcribed mRNA catabolic process, nonsense-mediated decay primary miRNA processing response to osmotic stress
commitment complex; mRNA cap binding complex; nuclear cap binding complex; nucleus; perinuclear region of cytoplasm
mRNA binding RNA cap binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Direct protein sequencing mRNA capping mRNA processing mRNA splicing mRNA transport Nonsense-mediated mRNA decay Nucleus Reference proteome RNA-binding Transport
MFNRKRRGDF
MFNRKRRGDFDEDENYRDFRPRMPKRQRIPPVVQLCKEMMPDIRTIGESVKAFEDDIKFLSEAIMNEYGHEDYFNNALLSTLNAVVVEQPQKQAAIALLTMVVNSKNNVAGKSIINYFFEELQKWCKQTYNDEFKSTSNETGPWNKIKLILRFLSILSPMFLVDELINIYKSLFELSIELNNLDPGNRVPLSEAIYTNTLLNIPYLFFFNRNNDGLRTKVEELLAYVEQNYLVKTTDINLLREYNGEPPYEMVELVRVVLPNVKKALINNLEQLNELFPDWNHLLTPQTGDEGFNDALTLPSVDDLKSFVRLNKNFGSVD...
7-methylguanosine mRNA capping mRNA 3'-end processing mRNA export from nucleus mRNA splicing, via spliceosome mRNA transcription by RNA polymerase II nuclear-transcribed mRNA catabolic process nuclear-transcribed mRNA catabolic process, nonsense-mediated decay primary miRNA processing response to osmotic stress commitm...
cell cycle cell differentiation negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II
chromatin; cytoplasm; nucleus
DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding
Saccharomyces cerevisiae
Cell cycle DNA-binding Homeobox Nucleus Reference proteome Repressor Transcription Transcription regulation
MSQETKMLPS
MSQETKMLPSLSSLLSGTEISSSPVSPSFTNPRTSFHLDDRGTIKLPPLNTSINRPRSVESALRHTVTSLHENSSAYGDDMLKHTQSDSALSSQLNSSQETVDESHENLLLTPLNSKKRDYSVSSKKNDILTPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPLARRKRRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQRIATSKSTTIIQTVSPPSPPLDVHATPLASRVKADILRDGSSCSRSSSSSPLENTPPRPHHSLNRRSSTPSIKRSQALTFHLNPQK...
cell cycle cell differentiation negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II chromatin; cytoplasm; nucleus DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymer...
negative regulation of ribosomal protein gene transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II regulation of transcription by RNA polymera...
core mediator complex; mediator complex; nucleus
protein domain specific binding TFIID-class transcription factor complex binding transcription coactivator activity
Saccharomyces cerevisiae
3D-structure Activator Nucleus Reference proteome Transcription Transcription regulation
MGKSAVIFVE
MGKSAVIFVERATPATLTELKDALSNSILSVRDPWSIDFRTYRCSIKNLPADVSKLMYSITFHHHGRQTVLIKDNSAMVTTAAAADIPPALVFNGSSTGVPESIDTILSSKLSNIWMQRQLIKGDAGETLILDGLTVRLVNLFSSTGFKGLLIELQADEAGEFETKIAGIEGHLAEIRAKEYKTSSDSLGPDTSNEICDLAYQYVRALEL
negative regulation of ribosomal protein gene transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II regulation of transcription by RNA polymera...
cellular lipid metabolic process lipid catabolic process sterol metabolic process
lipid droplet; membrane
sterol esterase activity
Saccharomyces cerevisiae
Acetylation Hydrolase Isopeptide bond Lipid degradation Lipid droplet Lipid metabolism Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Ubl conjugation
MYFPFLGRLS
MYFPFLGRLSITDYIIVVLVYIESIISSVLKLIPQPMINLFEWLINFSTSSDDNTIEEKLRSAPTIHEMCAIFDISVEDHLVRTEDNYILTLHRIPPISKNRFNNKVVYLHHGLLMCSDVWCCNIERHKNLPFVLHDLGYDVWMGNNRGNKYSTAHLNKPPKSNKFWDFSIDEFAFFDIPNSIEFILDITKVDKVICIGFSQGSAQMFAAFSLSEKLNRKVSHFIAIAPAMTPKGLHNRIVDTLAKSSPGFMYLFFGRKIVLPSAVIWQRTLHPTLFNLCIDIANKILFNWKSFNILPRQKIASYAKLYSTTSVKSIVHW...
cellular lipid metabolic process lipid catabolic process sterol metabolic process lipid droplet; membrane sterol esterase activity Saccharomyces cerevisiae Acetylation Hydrolase Isopeptide bond Lipid degradation Lipid droplet Lipid metabolism Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix...
cellular response to glucose starvation filamentous growth invasive growth in response to glucose limitation regulation of cellular response to glucose starvation regulation of protein-containing complex assembly signal transduction
cytoplasm; nucleotide-activated protein kinase complex; nucleus; plasma membrane
enzyme-substrate adaptor activity protein kinase binding
Saccharomyces cerevisiae
3D-structure Cell membrane Cytoplasm Lipoprotein Membrane Myristate Phosphoprotein Reference proteome
MGTTTSHPAQ
MGTTTSHPAQKKQTTKKCRAPIMSDVREKPSNAQGCEPQEMDAVSKKVTELSLNKCSDSQDAGQPSREGSITKKKSTLLLRDEDEPTMPKLSVMETAVDTDSGSSSTSDDEEGDIIAQTTEPKQDASPDDDRSGHSSPREEGQQQIRAKEASGGPSEIKSSLMVPVEIRWQQGGSKVYVTGSFTKWRKMIGLIPDSDNNGSFHVKLRLLPGTHRFRFIVDNELRVSDFLPTATDQMGNFVNYIEVRQPEKNPTNEKIRSKEADSMRPPTSDRSSIALQIGKDPDDFGDGYTRFHEDLSPRPPLEYTTDIPAVFTDPSVME...
cellular response to glucose starvation filamentous growth invasive growth in response to glucose limitation regulation of cellular response to glucose starvation regulation of protein-containing complex assembly signal transduction cytoplasm; nucleotide-activated protein kinase complex; nucleus; plasma membrane enzyme...
cytoplasmic translation eukaryotic translation initiation factor 4F complex assembly formation of translation preinitiation complex translational initiation
cytoplasm; cytoplasmic stress granule
mRNA binding ribosomal small subunit binding RNA binding RNA strand annealing activity RNA strand-exchange activity single-stranded RNA binding translation initiation factor activity
Saccharomyces cerevisiae
Initiation factor Phosphoprotein Protein biosynthesis Reference proteome Repeat RNA-binding
MAPPKKTVKK
MAPPKKTVKKMDLTSFLNDDTFGSSWAEEDVDLNKITIPIETANANTIPLSELAHAKNNSNNTRSGGFGGSFGGRSRLDPALGGGSSDRREEYPVPDAPPYRAVINNIPWDITPEGVQAWVEDGLVKPEAVEEVVLPKNLRDPTRLKGNAFVTLKERADLVAVLKFNGTKLNERTVYVSVAAPRRGGGADVDWSSARGSNFQGDGREDAPDLDWGAARGSNFRGPRREREEVDIDWTAARGSNFQGSSRPPRREREEVDIDWSAARGSNFQGSSRPPRREREEPDIDWSAARGSNFQSSSRPPRREREEPDIDWSAARGS...
cytoplasmic translation eukaryotic translation initiation factor 4F complex assembly formation of translation preinitiation complex translational initiation cytoplasm; cytoplasmic stress granule mRNA binding ribosomal small subunit binding RNA binding RNA strand annealing activity RNA strand-exchange activity single-st...
collagen catabolic process proteolysis
extracellular region
metal ion binding metalloendopeptidase activity toxin activity
Crotalus atrox
Cell adhesion impairing toxin Collagen degradation Direct protein sequencing Disulfide bond Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Platelet aggregation inhibiting toxin Protease Secreted Signal Toxin Zinc Zymogen
MIQVLLVTIC
MIQVLLVTICLAAFPYQGSSIILESGNVNDYEVIYPRKVTALPKGAVQPKYEDTMQYELKVNGEPVVLHLEKNKGLFSKDYSETHYSFDGRKITTNPSVEDHCYYHGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLKLSDSEAHAVFKLKNVEKEDEAPKMCGVTQNWESYEPIKKASDLNLNPEHQRYVELFIVVDHGMYTKYNGDSDKIRQRVHQMVNIMKESYTYMYIDILLAGIEIWSNGDLINVQPASPNTLNSFGEWRETDLLKRKSHDNAQLLTSIAFDEQIIGRAYIGGICDPKRSTGVVQDHSEIN...
collagen catabolic process proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Crotalus atrox Cell adhesion impairing toxin Collagen degradation Direct protein sequencing Disulfide bond Hemorrhagic toxin Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Plate...
germ cell development histidyl-tRNA aminoacylation mitochondrial translation nematode larval development translation
cytoplasm; cytosol; mitochondrion
ATP binding histidine-tRNA ligase activity identical protein binding RNA binding
Caenorhabditis elegans
Alternative splicing Aminoacyl-tRNA synthetase ATP-binding Ligase Nucleotide-binding Protein biosynthesis Reference proteome
MFRTITSRLA
MFRTITSRLAFSVRQAEETVKPRIAYAQRSGRRIKEKVALMQAKRKEAGETGAPEKPGKFVLKTGKGTRDYGPAQSALRNSVLQTVTETFNRYGAETIDTPVFELRDVLMGKYGEEGGKLVYDLQDQGGELLSLRYDLTVPFARYLAMNKITNITRYQIAKVYRRDQPVMSRGRYREFYQCDFDIAGQYDLMLPEAECLGIVDELLTKLEIGEFFINLNHRLILEGMFAVSGIPAKDFKTICSSVDKLDKTPWEDVEQEMINEKFLTKEQTGKLGELVRFRELNSDLNNLELLEKMSQLPDLGQNDKFKKGAEELKVLIE...
germ cell development histidyl-tRNA aminoacylation mitochondrial translation nematode larval development translation cytoplasm; cytosol; mitochondrion ATP binding histidine-tRNA ligase activity identical protein binding RNA binding Caenorhabditis elegansAlternative splicing Aminoacyl-tRNA synthetase ATP-binding Ligase ...
meiotic recombination checkpoint signaling mitotic DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling negative regulation of G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II phosphorylation
chromatin; cytoplasm; cytosol; nucleoplasm; nucleus; site of double-strand break
ATP binding protein serine kinase activity protein serine/threonine kinase activity
Schizosaccharomyces pombe
ATP-binding Cell cycle DNA damage Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase
MAQKLDNFPY
MAQKLDNFPYHIGREIGTGAFASVRLCYDDNAKIYAVKFVNKKHATSCMNAGVWARRMASEIQLHKLCNGHKNIIHFYNTAENPQWRWVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGISFMHSKGVAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSPVGSPPYAAPEITQQYDGSKVDVWSCGIILFALLLGNTPWDEAISNTGDYLLYKKQCERPSYHPWNLLSPGAYSIITGMLRSDPFKRYSVKHVVQHPWLTSSTPFRTKNGNCADPVALASRLMLKLRIDLDKPRLASSRASQNDSGF...
meiotic recombination checkpoint signaling mitotic DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling negative regulation of G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II phosphorylation chromatin; cytoplasm; cytosol; nucleoplasm; nucleus; site o...
cortical granule exocytosis cuticle development intra-Golgi vesicle-mediated transport intracellular protein transport retrograde transport, endosome to Golgi retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
cortical granule; cytoplasm; cytosol; dendrite; endomembrane system; Golgi apparatus; Golgi cisterna; perikaryon; plasma membrane; transport vesicle
GTP binding GTPase activity
Caenorhabditis elegans
Cell membrane Cell projection Cytoplasmic vesicle Golgi apparatus GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Protein transport Reference proteome Transport
MADFTNNALK
MADFTNNALKKFKLVFLGEQSVGKTSIITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSLIPSYIRDSSVAVVVYDITNANSFHQTTKWVDDVRNERGCDVIIVLVGNKTDLADKRQVSTEDGEKKARDLNVMFIETSAKAGYNVKQLFRKIATALPGIVQEETPEQPNIVIMNPPKDAEESQGRQCPC
cortical granule exocytosis cuticle development intra-Golgi vesicle-mediated transport intracellular protein transport retrograde transport, endosome to Golgi retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum cortical granule; cytoplasm; cytosol; dendrite; endomembrane system; Golgi apparatus; Golgi...
DNA damage checkpoint signaling G2/M transition of mitotic cell cycle
cytoplasm; nucleus
mRNA binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Phosphoprotein Reference proteome RNA-binding
METSSFENAP
METSSFENAPPAAINDAQDNNINTETNDQETNQQSIETRDAIDKENGVQTETGENSAKNAEQNVSSTNLNNAPTNGALDDDVIPNAIVIKNIPFAIKKEQLLDIIEEMDLPLPYAFNYHFDNGIFRGLAFANFTTPEETTQVITSLNGKEISGRKLKVEYKKMLPQAERERIEREKREKRGQLEEQHRSSSNLSLDSLSKMSGSGNNNTSNNQLFSTLMNGINANSMMNSPMNNTINNNSSNNNNSGNIILNQPSLSAQHTSSSLYQTNVNNQAQMSTERFYAPLPSTSTLPLPPQQLDFNDPDTLEIYSQLLLFKDREK...
DNA damage checkpoint signaling G2/M transition of mitotic cell cycle cytoplasm; nucleus mRNA binding Saccharomyces cerevisiae 3D-structure Cytoplasm Phosphoprotein Reference proteome RNA-binding METSSFENAP METSSFENAPPAAINDAQDNNINTETNDQETNQQSIETRDAIDKENGVQTETGENSAKNAEQNVSSTNLNNAPTNGALDDDVIPNAIVIKNIPFAIKKEQLLDIIEEMDLPL...
DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation
chromosome, telomeric region; NuA3 histone acetyltransferase complex; NuA3a histone acetyltransferase complex; NuA3b histone acetyltransferase complex; nucleus
histone acetyltransferase activity metal ion binding transcription coregulator activity
Saccharomyces cerevisiae
Acetylation Acyltransferase Chromatin regulator Direct protein sequencing Metal-binding Nucleus Reference proteome Transcription Transcription regulation Transferase Zinc Zinc-finger
MSLTANDESP
MSLTANDESPKPKKNALLKNLEIDDLIHSQFVRSDTNGHRTTRRLFNSDASISHRIRGSVRSDKGLNKIKKGLISQQSKLASENSSQNIVNRDNKMGAVSFPIIEPNIEVSEELKVRIKYDSIKFFNFERLISKSSVIAPLVNKNITSSGPLIGFQRRVNRLKQTWDLATENMEYPYSSDNTPFRDNDSWQWYVPYGGTIKKMKDFSTKRTLPTWEDKIKFLTFLENSKSATYINGNVSLCNHNETDQENEDRKKRKGKVPRIKNKVWFSQIEYIVLRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQ...
DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation chromosome, telomeric region; NuA3 histone acetyltransferase complex; NuA3a histone acetyl...
regulation of DNA-templated transcription regulation of transcription by RNA polymerase II
cytoplasm; nucleus; Rpd3L-Expanded complex
DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding
Saccharomyces cerevisiae
Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome
MTLPKLSSVS
MTLPKLSSVSVSSGHVSANSHGFSILSKHPHPNNLVHSHSLSHTNAKSHLPISSTSTKENSTNKEEAESLKKNNPSSWDPSDDIKLRHLKEIKNLGWKEIAHHFPNRTPNACQFRWRRLKSGNLKSNKTAVIDINKLFGVYATGDATPSAGTPSAEEAVKEEAVEDEDITAGSSAIEDSPPDFKPLVKPKYMDRKLITQRSTSTFSDHEPQHTKPRKLFVKPRSFSHSITTNTPNVKTAQQTNLSLYNTTSAKTNKAVNSNDYENIGLVPKIIIRSRRNSFIPSTQIPHSTTKTRKNSHSVISSRRSSFNMMHSRRSSFN...
regulation of DNA-templated transcription regulation of transcription by RNA polymerase II cytoplasm; nucleus; Rpd3L-Expanded complex DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding Saccharomyces ce...
regulation of cyclin-dependent protein serine/threonine kinase activity
cytoplasm; nucleus
metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity
Saccharomyces cerevisiae
Cytoplasm Hydrolase Magnesium Manganese Metal-binding Nucleus Phosphoprotein Protein phosphatase Reference proteome
MGQILSNPII
MGQILSNPIIDKEHHSGTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGMLEQCLIDTFLATDVELLKDEKLKDDHSGCTATVILVSQLKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIVALLKENESESQWFERMRSKNYNIQTSFVQ...
regulation of cyclin-dependent protein serine/threonine kinase activity cytoplasm; nucleus metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity Saccharomyces cerevisiae Cytoplasm Hydrolase Magnesium Manganese Metal-binding Nucleus Phosphoprotein Protein phosphatase Reference prot...
ascospore formation autophagosome assembly glycogen metabolic process Golgi organization membrane fusion nuclear membrane reassembly piecemeal microautophagy of the nucleus proteasome-mediated ubiquitin-dependent protein catabolic process sister chromatid biorientation ubiquitin-dependent ERAD pathway
cytoplasm; cytosol; nucleus
protein phosphatase regulator activity ubiquitin binding
Saccharomyces cerevisiae
3D-structure Cytoplasm Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation Ubl conjugation pathway
MAEIPDETIQ
MAEIPDETIQQFMALTNVSHNIAVQYLSEFGDLNEALNSYYASQTDDQKDRREEAHWNRQQEKALKQEAFSTNSSNKAINTEHVGGLCPKPGSSQGSNEYLKRKGSTSPEPTKGSSRSGSGNNSRFMSFSDMVRGQADDDDEDQPRNTFAGGETSGLEVTDPSDPNSLLKDLLEKARRGGQMGAENGFRDDEDHEMGANRFTGRGFRLGSTIDAADEVVEDNTSQSQRRPEKVTREITFWKEGFQVADGPLYRYDDPANSFYLSELNQGRAPLKLLDVQFGQEVEVNVYKKLDESYKAPTRKLGGFSGQGQRLGSPIPGE...
ascospore formation autophagosome assembly glycogen metabolic process Golgi organization membrane fusion nuclear membrane reassembly piecemeal microautophagy of the nucleus proteasome-mediated ubiquitin-dependent protein catabolic process sister chromatid biorientation ubiquitin-dependent ERAD pathway cytoplasm; cytoso...
actin cortical patch localization positive regulation of phosphatidylinositol biosynthetic process protein localization regulation of ARF protein signal transduction
cellular bud neck; cellular bud tip; cytoplasm; plasma membrane
guanyl-nucleotide exchange factor activity
Saccharomyces cerevisiae
Cell membrane Cytoplasm Guanine-nucleotide releasing factor Membrane Phosphoprotein Reference proteome
MCASLNEVKK
MCASLNEVKKNDTYGVSQKGYNDNFSESEGVLHGSKSMPTSMKNMLQSPTMVNMCDILQNKEAANDEKPVIPTTDTATAGTGTEDISSTQSEETDQNSHLIASEILEGTFKDVSYKEYANFLGNDNNNQVLTEFVKLLSPLPSSLLETLFNLSKSIYFIAEAQNIDRILECLSIEWIACHPNTHWKSGYKSCHIVLFSLLILNSDLHNNFQVDHKKIKFSMVAFINNTLRALREENEYEELKIYSREHLIIEELSEYYKTLNETPLPLCTESRTSINISDNQSSLKRFSTLGSREFSTSNLRSVNSNSTTLYSRDGQVSV...
actin cortical patch localization positive regulation of phosphatidylinositol biosynthetic process protein localization regulation of ARF protein signal transduction cellular bud neck; cellular bud tip; cytoplasm; plasma membrane guanyl-nucleotide exchange factor activity Saccharomyces cerevisiae Cell membrane Cytopla...
fungal-type cell wall chitin biosynthetic process
cellular bud neck; incipient cellular bud site; membrane; plasma membrane
enzyme activator activity
Saccharomyces cerevisiae
Cell membrane Lipoprotein Membrane Methylation Phosphoprotein Prenylation Reference proteome Repeat
MASSPQVHPY
MASSPQVHPYKKHLMQSQHINFDNRGLQFQNSSLKVGQDFSDNKENRENRDNEDFSTADLPKRSANQPLINEHLRAASVPLLSNDIGNSQEEDFVPVPPPQLHLNNSNNTSLSSLGSTPTNSPSPGALRQTNSSTSLTKEQIKKRTRSVDLSHMYLLNGSSDTQLTATNESVADLSHQMISRYLGGKNNTSLVPRLKTIEMYRQNVKKSKDPEVLFQYAQYMLQTALTIESSNALVQDSDKEGNVSQSDLKLQFLKEAQSYLKKLSIKGYSDAQYLLADGYSSGAFGKIENKEAFVLFQAAAKHGHIESAYRASHCLEEG...
fungal-type cell wall chitin biosynthetic process cellular bud neck; incipient cellular bud site; membrane; plasma membrane enzyme activator activity Saccharomyces cerevisiae Cell membrane Lipoprotein Membrane Methylation Phosphoprotein Prenylation Reference proteome Repeat MASSPQVHPY MASSPQVHPYKKHLMQSQHINFDNRGLQFQNSS...
cell redox homeostasis cellular response to oxidative stress
cytosol; mitochondrion
thioredoxin peroxidase activity
Saccharomyces cerevisiae
3D-structure Antioxidant Disulfide bond Mitochondrion Oxidoreductase Peroxidase Phosphoprotein Redox-active center Reference proteome Transit peptide
MFSRICSAQL
MFSRICSAQLKRTAWTLPKQAHLQSQTIKTFATAPILCKQFKQSDQPRLRINSDAPNFDADTTVGKINFYDYLGDSWGVLFSHPADFTPVCTTEVSAFAKLKPEFDKRNVKLIGLSVEDVESHEKWIQDIKEIAKVKNVGFPIIGDTFRNVAFLYDMVDAEGFKNINDGSLKTVRSVFVIDPKKKIRLIFTYPSTVGRNTSEVLRVIDALQLTDKEGVVTPINWQPADDVIIPPSVSNDEAKAKFGQFNEIKPYLRFTKSK
cell redox homeostasis cellular response to oxidative stress cytosol; mitochondrion thioredoxin peroxidase activity Saccharomyces cerevisiae 3D-structure Antioxidant Disulfide bond Mitochondrion Oxidoreductase Peroxidase Phosphoprotein Redox-active center Reference proteome Transit peptide MFSRICSAQL MFSRICSAQLKRTAWTL...
fatty acid beta-oxidation fatty acid transmembrane transport fatty-acyl-CoA transport long-chain fatty acid catabolic process long-chain fatty acid import into peroxisome peroxisome organization very long-chain fatty acid catabolic process
ATP-binding cassette (ABC) transporter complex; peroxisomal membrane; peroxisome
ABC-type transporter activity ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity long-chain fatty acid transporter activity
Saccharomyces cerevisiae
ATP-binding Glycoprotein Membrane Nucleotide-binding Peroxisome Reference proteome Transmembrane Transmembrane helix Transport
MISTASAFYQ
MISTASAFYQKHRVNLLRSSYIILLLATLYNSNSSSSNNKTDKKDSESTVLENKKIEEGKETAVDREEDESSKEELTIVSKHSTDSEDGAIIIDKESKTNHKGGERKGKVDFLFKLLLHDKKCLILFITQAILLNIRTLLSLRVATLDGQLVSTLVRAQYANFTKILLGKWMILGIPASFINSLISYTTKLCAVTINRKVSDFLLSKYLSNHHTFYSVASAESVSEIQDNLTKDIYTFSMNSSLLLNQLLKPMLDLILCSFKLLTSNTSVMGEGTLALGLIVYASNSLLKLIQPNFTRLTMASASLESWFRSLHSNLHSS...
fatty acid beta-oxidation fatty acid transmembrane transport fatty-acyl-CoA transport long-chain fatty acid catabolic process long-chain fatty acid import into peroxisome peroxisome organization very long-chain fatty acid catabolic process ATP-binding cassette (ABC) transporter complex; peroxisomal membrane; peroxisome...
chromatin organization negative regulation of transcription by RNA polymerase II positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter
cellular bud; nucleus; Rpd3L complex; Rpd3L-Expanded complex
cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific zinc ion binding
Saccharomyces cerevisiae
Chromatin regulator DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger
MSSLYIKTPL
MSSLYIKTPLHALSAGPDSHANSSYYDNLLLPSFSNLSSNISRNNITTDNNINSASPRKYSFHSLNVSPILSPISLANEILGKKSNTAPASPHHMDYNPISSLTPGNSPEFNKASLSQISFTNPLNYGSGLGFSSNSQPRLPLLDRLSSVSLSKRPERPQQSLPSLRHLQLLPSPLLQENAARFPDTSKRTSNWKTDLTHWCKDTNYQDYVKIREEVAHFKPLSIPNLTNNQNNDSFNYGKELESTRSSKFHSPSKESFDRTKLIPSILEAKDQFKDLSNNAWSITPPVTPPMSPPTNRTMERTTLRGVEASFFEGKSSN...
chromatin organization negative regulation of transcription by RNA polymerase II positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter cellular bud; nucleus; Rpd3L complex; Rpd3L-Expanded complex cis-regulatory region sequence-specific DNA binding DNA-binding...
DNA replication initiation DNA replication preinitiation complex assembly double-strand break repair via break-induced replication mitotic DNA replication checkpoint signaling mitotic DNA replication preinitiation complex assembly negative regulation of protein-containing complex assembly regulation of mitotic DNA repl...
cytoplasm; DNA replication preinitiation complex; nucleus
DNA replication origin binding single-stranded DNA binding
Saccharomyces cerevisiae
Cell cycle DNA replication Nucleus Phosphoprotein Reference proteome
MYSFELDKLK
MYSFELDKLKIELKTWEHDFIDKNKREPTRDDIKSLRTVRQMYKQYSTLKKKQSLQRQKVDTQESVELPAHKKDHDEVVEIGPTPQVYGKAISIFDMNLSPIKPIYMTFTNNIDVNNDNSKTISNESSPRKTILLKSSPADRTLVAEPISSVKRQLNFQMLNASSTRTPTSSPCKNRNGKLVEIKKCSPTINPPLESGKPSGYYGPNSPLKLDEENIHLNISLNSSTKRRLQIAYPSLQKTPSKDQADISTSFSPSPLIRRPLTKSLIELAREHTEIVKEFGVLQEEDIEEEEEGEEGENGYDEKNHEDDFGLEDELIRP...
DNA replication initiation DNA replication preinitiation complex assembly double-strand break repair via break-induced replication mitotic DNA replication checkpoint signaling mitotic DNA replication preinitiation complex assembly negative regulation of protein-containing complex assembly regulation of mitotic DNA repl...
determination of adult lifespan endocytosis positive regulation of egg-laying behavior regulation of endocytosis response to caloric restriction response to paraquat
cytoplasmic vesicle; cytoplasmic vesicle membrane; neuron projection; synapse
acetylcholine receptor activity extracellular ligand-gated monoatomic ion channel activity monoatomic ion channel activity neurotransmitter receptor activity
Caenorhabditis elegans
Cytoplasmic vesicle Disulfide bond Endocytosis Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Receptor Reference proteome Signal Transmembrane Transmembrane helix Transport
MKIIIFVCFI
MKIIIFVCFILIFYLPIQKKHVNSQQQGIDSDDGDAESFFNKSYSEHQSALEQKIFRGYNPKNRPMKNASFPTIVDVHWHIIHVSINQREQTMTVHGHIYMRWFDEFLVWDPKDFNNIQYARVKKWQVWQPKIKVSNSASGLGSAFDFSTSAHVIIQMMGKDRAKVEMYPTFSIKVGCAFDFTDYPYDLNKCAINLFSTSTMADVQLQNLYAIPPTLSFGWEEQKMKRIISDFKIQNVSSSALYYTNGNITSSAPITGFDLGSTWSMLAVTVSFVRHSPLFEAAVVTPCIVVASLISMTFFIDSLSSTFLLMMLHFYVQL...
determination of adult lifespan endocytosis positive regulation of egg-laying behavior regulation of endocytosis response to caloric restriction response to paraquat cytoplasmic vesicle; cytoplasmic vesicle membrane; neuron projection; synapse acetylcholine receptor activity extracellular ligand-gated monoatomic ion ch...
potassium ion transport tyrosine metabolic process
membrane
iodotyrosine deiodinase activity oxidoreductase activity
Caenorhabditis elegans
Flavoprotein FMN Ion transport Membrane Oxidoreductase Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport
MKKHTHHKAY
MKKHTHHKAYGDSTGKEPLIDLQSIKLWLNSFGNQGHSSEAVLNVLFTLGVILFVIYQVASLLHRMNKRVEKQLESRTKQRKVEVADKHVGDEMVFTDLHENVIRERMIPYRMPVINDDITLRNSQIFYEEMKMRRSCRQFSSRDVPLKVIQNLLKTAGTSPSVGNLQPWTFCVVSSDSIKTMIRKILEADERDNYVSRKKGASWVVDVSQLQDTWRRPYITDAPYLLIVCHEIFRDVHSKTERVFHYNQISTSIAVGILLAAIQNVGLSTVVTSPLNAGPDISRILRRPENESILLLLPLGYASEDVLVPDLKRKPVEH...
potassium ion transport tyrosine metabolic process membrane iodotyrosine deiodinase activity oxidoreductase activity Caenorhabditis elegansFlavoprotein FMN Ion transport Membrane Oxidoreductase Potassium Potassium transport Reference proteome Transmembrane Transmembrane helix Transport MKKHTHHKAY MKKHTHHKAYGDSTGKEPLIDL...
astral microtubule organization attachment of spindle microtubules to kinetochore cell division chromosome segregation establishment of protein localization kinetochore assembly meiotic chromosome separation meiotic metaphase I homologous chromosome alignment meiotic spindle organization mitotic spindle assembly checkp...
cell cortex; chromatin; chromosome; kinetochore; outer kinetochore
microtubule binding protein-containing complex binding
Caenorhabditis elegans
Cell cycle Cell division Centromere Chromosome Chromosome partition Coiled coil Cytoplasm Kinetochore Meiosis Mitosis Reference proteome Repeat
MSMEPRKKRN
MSMEPRKKRNSILKVRQAVETIEETVMNSGPSSTTTNRRVSFHNVKHVKQYDRDHGKILDATPVKEKITDTIGSDGILTPRGGNMDISESPACTSSFQVFGGGNLDKTMDMSLETTINENNETARLFETTRDPTLLYEKIVETTTKVTERIVSMPLDDTLAMFNTTNQEDKDMSVDRSVLFTIPKVPKHNATMNRTIPMDLDESKAAGGQCDETMNVFNFTNLEAAEMDTSKLDENNTMNAIRIPINSNVMPVDMDITEHHTLIEEKKNDTFGPSQLMDISAPQVQVNDTLAIFNSPRDICNKGLGVPQNLINIASNVVP...
astral microtubule organization attachment of spindle microtubules to kinetochore cell division chromosome segregation establishment of protein localization kinetochore assembly meiotic chromosome separation meiotic metaphase I homologous chromosome alignment meiotic spindle organization mitotic spindle assembly checkp...
piRNA processing RNA methylation siRNA processing
cytoplasm; nucleoplasm; nucleus; perinuclear region of cytoplasm
metal ion binding O-methyltransferase activity RNA binding RNA methyltransferase activity small RNA 2'-O-methyltransferase activity
Caenorhabditis elegans
Cytoplasm Magnesium Metal-binding Methyltransferase Nucleus Reference proteome RNA-binding RNA-mediated gene silencing S-adenosyl-L-methionine Transferase
MAHTSDGWGA
MAHTSDGWGAPYDNQTYVEAYEQLEIALLEPLDRILETANVEEFRPKFKNHQDPNDRKNKKNNDEEWRDSIYNIATDESDTDDHEQRKNFFQPPLQVQRNSFVKNTLMEFKRSSQIDISRLAVMGCGEMSLEKGICEYLGSFGTINVLSVDIDEPSLSIGQQLLGKHLERNAEILAVETGLPVLMRSYVGDILEPDHRFADVDAIVSMEVVEHIPLPNAKKFVENVLGTLMPRIFIFSTPNHEYNAVFGMEPGEFRHGDHKFEMNRKEFSNWLEELSIRFPHYQIDPPHYIGMTRGYENLSGASQAAVCRLQVDLNTTLP...
piRNA processing RNA methylation siRNA processing cytoplasm; nucleoplasm; nucleus; perinuclear region of cytoplasm metal ion binding O-methyltransferase activity RNA binding RNA methyltransferase activity small RNA 2'-O-methyltransferase activity Caenorhabditis elegansCytoplasm Magnesium Metal-binding Methyltransferase...
adult locomotory behavior associative learning feeding behavior forward locomotion habituation hyperosmotic response ionotropic glutamate receptor signaling pathway modulation of chemical synaptic transmission positive regulation of backward locomotion positive regulation of forward locomotion regulation of backward lo...
cell surface; dendrite; ionotropic glutamate receptor complex; neuron projection; neuron projection membrane; neuronal cell body; perikaryon; perinuclear endoplasmic reticulum; plasma membrane; postsynaptic density; postsynaptic density membrane; postsynaptic membrane; recycling endosome; synapse
AMPA glutamate receptor activity enzyme binding glutamate receptor activity glutamate-gated receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
Caenorhabditis elegans
Cell membrane Cell projection Endoplasmic reticulum Endosome Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport Ubl conjugation
MFSSFSFLNM
MFSSFSFLNMFGVLFTVFNLTVVQPYPSHIIIKSFGNNEEVSRVALKAMEYTSDHINSRDDVPFKLAFDHRVVEEGAAVSWNMVNAVCDELKEGAMALLSSVDGKGREGIRGVSDALEMPLVSLTALSNDDHQQQQFGNLFEVSVRPPISELLADFIVHKGWGEVLVLIDPVHASLHLPSLWRHLRTRTNTSVKASMFDLPADEKQFEAYLMQFNMMRNNETNRILIDCASPKRLKKLLINIRSAQFNQANYHYVLANYDFLPYDQEMFQNGNINISGFNIINKDGREYWSLKKHLKTSSSLGGGDDVSVEAAVGHDAML...
adult locomotory behavior associative learning feeding behavior forward locomotion habituation hyperosmotic response ionotropic glutamate receptor signaling pathway modulation of chemical synaptic transmission positive regulation of backward locomotion positive regulation of forward locomotion regulation of backward lo...
cellular response to calcium ion mitochondrion organization muscle cell cellular homeostasis necroptotic process positive regulation of sarcomere organization proteolysis
cytoplasm; M band; sarcomere
calcium-dependent cysteine-type endopeptidase activity
Caenorhabditis elegans
Alternative splicing Cytoplasm Hydrolase Protease Reference proteome Thiol protease
MADDEEEIIQ
MADDEEEIIQKVEVKPDEFNGLIGSIAGNLIRDKVGGAGGDILGGLASNFFGGGGGGGGGGGGGGFGGGNGGFGGGSNYDQGGNGNSGDQQKRKRDMAKDLIGGIFDNVVNRKGKKEQDNYGGGGNYGGGGGNQGGGGGGGFNFNDIGGLINSMGGGGGGGQRQGGGGGGFGDILGGIGSLIGGGGGGQYNGGGGNVNPNNLNGGMVNVIGNLIGEAAHRFLGVDPGTGRIIGAVAGNVIMGLGGKDNSLGNIGKVILDNIISGKFRRDVDPFVRPGPDPDRGGGGSGPSPISPRPTTEPQDFYELRDQCLESKRLFEDP...
cellular response to calcium ion mitochondrion organization muscle cell cellular homeostasis necroptotic process positive regulation of sarcomere organization proteolysis cytoplasm; M band; sarcomere calcium-dependent cysteine-type endopeptidase activity Caenorhabditis elegansAlternative splicing Cytoplasm Hydrolase Pr...
chromosome segregation intracellular signal transduction phosphorylation regulation of transcription by RNA polymerase II
chromatin; nucleus
ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity
Caenorhabditis elegans
Alternative splicing ATP-binding Developmental protein Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transcription Transcription regulation Transferase
MSMLSMDGIV
MSMLSMDGIVAGGGSSSGGGERSFVLEQKMFNTGPQNKALPTVQSSGSSSNHAPIVGESPLGTVSSTMATGDTGRVGNVTYMSSGMLGATQFMPQNSSHPSTSVMMQQVPPQNGGATRSSPTEMQQCMQAMSEDSIEMRDYNSGVHHMHPHQMQMQQQQQHHQQQYNMSYHNHQQQMQQMHYHQQQQQYQQQQAQHHQMYAPQIQQQQQQPQQQSQQQSAQQPQQSSAALQHVNESSNLSSAGSISDREPEQHGGTPQRPTAPQSSTATDKKTRKRRKAGPTEDQATPKQERKITEFMKVGGEVASGNSVARCLLTEYHQ...
chromosome segregation intracellular signal transduction phosphorylation regulation of transcription by RNA polymerase II chromatin; nucleus ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity Caenorhabditis elegansAlternative splicing ATP-binding Developmental pr...
embryonic body morphogenesis epidermal cell fate specification formation of anatomical boundary negative regulation of transcription by RNA polymerase II neuron differentiation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II
cytoplasm; nucleus
DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding
Caenorhabditis elegans
Cytoplasm Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation
MILKFGIERI
MILKFGIERILSSPYPCPSPTISTPATSPSSISPTFASPNGTPNIASSMYPAWVFSTRYSDRPSAGPRHRKSRKRESTGSSGSSEEEKRPRTAFTGDQLDRLKTEFRESRYLTEKRRQELAHELGLNESQIKIWFQNKRAKLKKSTSSVPRDRCSSVTPNPHNHPSIHGGYQLMAQLAKVQARAYMP
embryonic body morphogenesis epidermal cell fate specification formation of anatomical boundary negative regulation of transcription by RNA polymerase II neuron differentiation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoplasm; nucleus DNA-binding trans...
centrosome cycle female meiosis II meiotic chromosome segregation mitotic nuclear membrane disassembly mitotic spindle organization phosphorylation polar body extrusion after meiotic divisions positive regulation of nematode male tail tip morphogenesis regulation of cell cycle
centrosome; condensed chromosome; cytoplasm; kinetochore; midbody; nucleus; spindle midzone; spindle pole
ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity
Caenorhabditis elegans
Alternative splicing ATP-binding Cell cycle Cell division Centromere Chromosome Cytoplasm Cytoskeleton Kinase Kinetochore Meiosis Mitosis Nucleotide-binding Nucleus Reference proteome Repeat Serine/threonine-protein kinase Transferase
MNRLPNIAKP
MNRLPNIAKPPQKSNQRKEKAPPEVPALIADKDRGTYYEKGRFLGKGGFAHCYELTNRATREVVAGKVVPKSMLVKQYQRDKVDNERILIHRELGHINIVKLFNFFEDNLNVYITLELCARRSLMELHKRRKAVTEPEARYFTHQIVDGVLYLHDLNIIHRDMKLGNLFLNDDLVVKIGDFGLATTVNGDERKKTLCGTPNYIAPEVLNKAGHSFEVDIWAVGCILYILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAKQVQRDGFFKSGFMPTRLPVSCLTMVPKFGGHETSMMEE...
centrosome cycle female meiosis II meiotic chromosome segregation mitotic nuclear membrane disassembly mitotic spindle organization phosphorylation polar body extrusion after meiotic divisions positive regulation of nematode male tail tip morphogenesis regulation of cell cycle centrosome; condensed chromosome; cytoplas...
cell division meiotic chromosome condensation meiotic chromosome segregation mitotic sister chromatid segregation mitotic sister chromatid separation
chromosome, centromeric region; condensin complex; nucleus
chromatin binding
Caenorhabditis elegans
Cell cycle Cell division Centromere Chromosome Coiled coil Meiosis Mitosis Nucleus Reference proteome
MTRNAPPGQE
MTRNAPPGQESTDLAWLVTPAKDLVENFSIDVLKALAGYLEVIRQESEDTDNQVDAATTYRLFDFQRACRIIQGSCAVYGRKVDHVYELTISVVDLVENKGQDDGNTGSRRGAGRRKNFNLGSTNYDLADIDSLKQEALANFEKTVKEEKKSIDAVRMVENAEVIESQYERKSCLVAKPTQFMFKLNYGQLNRTDEQILNAKSRPDVIGKVKDFEIKKSKVKHDQQILYSHDCYRGNLDQFTLPGARWMPDNKELAANFGVADLEVELDLEQEHEKISAYGPFKDPLSGREVVPPPRWFIEQEAVRQNQEIQSRATSRAI...
cell division meiotic chromosome condensation meiotic chromosome segregation mitotic sister chromatid segregation mitotic sister chromatid separation chromosome, centromeric region; condensin complex; nucleus chromatin binding Caenorhabditis elegansCell cycle Cell division Centromere Chromosome Coiled coil Meiosis Mito...
cellular response to extracellular stimulus glutathione metabolic process protein glutathionylation response to oxidative stress response to superoxide
cytoplasm
glutathione dehydrogenase (ascorbate) activity glutathione transferase activity methylarsonate reductase activity
Caenorhabditis elegans
Cytoplasm Oxidoreductase Reference proteome Transferase
MVLTGVTSKA
MVLTGVTSKAIRKGDAEPPLSKGSFRVYNMRFCPWAERAMLYVAAKGIEAEVVNLNVTDKLEWYWTKHYQGKAPAVEHNGKVVIESGFIPEYLDDAFPETRILPTDPYEKVQQKLLADRLTAVAHAVPLLFAVMRDRTLKDEKQRKVFEVLKQAENLLANDFYAGSQPGYPDYLSFPFFEKIWWSASLDGVVDLPTIEFPGEEEYPKLTKWFQKMISSDVVQSVTQSLEHGAAFMNAYATHQELNYDLGL
cellular response to extracellular stimulus glutathione metabolic process protein glutathionylation response to oxidative stress response to superoxide cytoplasm glutathione dehydrogenase (ascorbate) activity glutathione transferase activity methylarsonate reductase activity Caenorhabditis elegansCytoplasm Oxidoreducta...
fertilization flagellated sperm motility phosphatidylinositol dephosphorylation phosphatidylinositol metabolic process positive regulation of flagellated sperm motility regulation of brood size
axon; cytoplasm; dendrite; membrane; neuronal cell body; non-motile cilium; nucleus
phosphatidylinositol phosphate phosphatase activity phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
Caenorhabditis elegans
Cytoplasm Hydrolase Reference proteome
MDWKITIFTY
MDWKITIFTYNLAMKASDSEAVHNMLNGMIDDHTHLVAIGLQEVAHSETIGGAVLTWATTIASWMNTNGRMVLLAKTFQATNQVLIFGRKQLIGQIKRIDYRFQRNTMGGLTGHKGSIGVRLQLASPYSIVFVDSHFIHGPENYGKRVEQYHTNRNCSFPEDKSVRAAFWFGDFNFRVEEDVNTVIRKIKNGTHLELLDTREQLKRALVERDAFIGFHEQPVTFEPTYRVTVGTTEQDGKRVPSWTDRILYKGDGITGLSYTNNKKAVASDHLPVVAMFRVTAPAAPKPQWEVIFEHLPTWYTSIPLVGRFQVNELYYKE...
fertilization flagellated sperm motility phosphatidylinositol dephosphorylation phosphatidylinositol metabolic process positive regulation of flagellated sperm motility regulation of brood size axon; cytoplasm; dendrite; membrane; neuronal cell body; non-motile cilium; nucleus phosphatidylinositol phosphate phosphatase...
axon regeneration cell projection morphogenesis egg-laying behavior lamellipodium assembly locomotion mesodermal cell migration neuron migration presynapse assembly regulation of cell migration signal transduction vulval development
filamentous actin; growth cone membrane; lamellipodium; neuronal cell body membrane; perikaryon; presynaptic cytosol
SH3 domain binding
Caenorhabditis elegans
Alternative splicing Developmental protein Neurogenesis Reference proteome
MDSCEEECDL
MDSCEEECDLEVDSDEEDQLFGEKCISLLSSLLPLSSSTLLSNAINLELDEVERPPPLLNVLEEQQFPKVCANIEEENELEADTEEDIAETADDEESKDPVEKTENFEPSVTMDTYDFPDPYPVQIRARPQVPPKPPIDTVRYSMNNIKESADWQLDELLEELEALETQLNSSNGGDQLLLGVSGIPASSSRENVKSISTLPPPPPALSYHQTPQQPQLLHHHNNHLGYQNGIHQITSINSAASSCSSPDGDSAFGDSSSTESSNNRCRNSAFSSNDSCRDSLNTPSPTQVSPRNGELNAEEAKAQKIRQALEKMKEAKV...
axon regeneration cell projection morphogenesis egg-laying behavior lamellipodium assembly locomotion mesodermal cell migration neuron migration presynapse assembly regulation of cell migration signal transduction vulval development filamentous actin; growth cone membrane; lamellipodium; neuronal cell body membrane; pe...
DNA replication embryo development ending in birth or egg hatching error-prone translesion synthesis reproduction translesion synthesis
nucleus
damaged DNA binding DNA-directed DNA polymerase activity metal ion binding
Caenorhabditis elegans
Alternative splicing DNA damage DNA repair DNA replication DNA synthesis DNA-directed DNA polymerase Magnesium Metal-binding Mutator protein Nucleotidyltransferase Nucleus Reference proteome Schiff base Transferase Zinc Zinc-finger
MLTFNDNKAG
MLTFNDNKAGMNGLDKEKITKVIEENTSASYSSFSKKQQSRIEEKVLEIKNRLQTATREERQKSEILMENLEMKLESSRDLSRDCVCIDMDAYFAAVEMRDNPALRTVPMAVGSSAMLSTSNYLARRFGVRAGMPGFISNKLCPSLTIVPGNYPKYTKVSRQFSQIFMEYDSDVGMMSLDEAFIDLTDYVASNTEKKTFKRHRFGGDCPCWLPRFDENENTLEDLKIEESICPKCEKSRKIYYDHVEFGTGREEAVREIRFRVEQLTGLTCSAGIASNFMLAKICSDLNKPNGQYVLENDKNAIMEFLKDLPIRKVGGIG...
DNA replication embryo development ending in birth or egg hatching error-prone translesion synthesis reproduction translesion synthesis nucleus damaged DNA binding DNA-directed DNA polymerase activity metal ion binding Caenorhabditis elegansAlternative splicing DNA damage DNA repair DNA replication DNA synthesis DNA-di...
carbohydrate metabolic process cell differentiation nervous system development protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
cytoplasm; endoplasmic reticulum membrane; nuclear inner membrane; perinuclear region of cytoplasm
mannosyltransferase activity
Caenorhabditis elegans
3D-structure Developmental protein Differentiation Endoplasmic reticulum Glycosyltransferase Membrane Neurogenesis Reference proteome Transferase Transmembrane Transmembrane helix
MAKKPKNSPE
MAKKPKNSPEKSKYSSDTSSSLYSQTWLASVVIIGLLVGYINYQHVYTLFENDKHFSHLADFEREMAYRTEMGLYYSYYKTIINAPSFLEGVQEITHDTVTEHGHEINTLNRFNLYPEVILAFLYRPFRAFAKSANWQIELCWQVNRGELRPVESCEGIGNPHYFYITGVFIVAGTVASSIFYLGVLVSDSIFGGFLSVLCFAFNHGEATRVQWTPPLRESFAFPFIIGHIAILTFVIKYKKSGHSMILLLTSMAVPALLFWQFTQFAFFTQICSIFLAFSLDLIPFSTAKTVIHSHIISFLIGFLLLFGNEMMITALYF...
carbohydrate metabolic process cell differentiation nervous system development protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan cytoplasm; endoplasmic reticulum membrane; nuclear inner membrane; perinuclear region of cytoplasm mannosyltransferase activity Caenorhabditis elegans3D-structure Developmenta...
mitotic sister chromatid segregation
condensed chromosome; nucleosome; nucleus
DNA binding protein heterodimerization activity structural constituent of chromatin
Caenorhabditis elegans
Chromosome DNA-binding Nucleosome core Nucleus Reference proteome
MADDGPIIEE
MADDGPIIEEIAEKNGRVARIMQRLQHDTQRVTSVPGFNTSATGYADLIALLDQYKNDLEAVGFNDLEQARRRAPSVDITVGSNSTNLVDYSHGRHDMPSHRRHDSSDEEITAANSHHQSPINVGNRNDTDGTNGRNGSRAGSSSSDRVRMIAGRNRISKTRRYRPGQKALEEIRKYQESEDLLIPKAPFARLVREIMQTSTPFSSDLRIRSDAINALQEASEALLVQMFDGSSLISAHSKRATLTTTDVQLYRRLCLPNL
mitotic sister chromatid segregation condensed chromosome; nucleosome; nucleus DNA binding protein heterodimerization activity structural constituent of chromatin Caenorhabditis elegansChromosome DNA-binding Nucleosome core Nucleus Reference proteome MADDGPIIEE MADDGPIIEEIAEKNGRVARIMQRLQHDTQRVTSVPGFNTSATGYADLIALLDQYKND...