Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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autophagy proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process protein folding protein refolding | cytoplasm; cytosol; nucleus | adenyl-nucleotide exchange factor activity ATP binding ATP-dependent protein folding chaperone calmodulin binding peptide binding | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Calmodulin-binding Chaperone Cytoplasm Direct protein sequencing Isopeptide bond Nucleotide-binding Phosphoprotein Reference proteome Stress response Ubl conjugation | MSTPFGLDLG | MSTPFGLDLGNNNSVLAVARNRGIDIVVNEVSNRSTPSVVGFGPKNRYLGETGKNKQTSNIKNTVANLKRIIGLDYHHPDFEQESKHFTSKLVELDDKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDTVKQDTKANITDVCIAVPPWYTEEQRYNIADAARIAGLNPVRIVNDVTAAGVSYGIFKTDLPEGEEKPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRDFDLAITEHFADEFKTKYKIDIRENPKAYNRILTAAEKLKKVLSANTNAPFSVESVMNDVDVSSQLSREELEELVKPLLERVTEP... | autophagy proteasomal ubiquitin-independent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process protein folding protein refolding cytoplasm; cytosol; nucleus adenyl-nucleotide exchange factor activity ATP binding ATP-dependent protein folding chaperone calmodulin binding peptide ... |
carbon catabolite activation of transcription from RNA polymerase II promoter chromatin remodeling positive regulation of DNA-templated transcription positive regulation of mating type switching positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | chromatin; cytosol; nucleus; SWI/SNF complex | DNA binding histone binding | Saccharomyces cerevisiae | 3D-structure Activator DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MENTLGEGST | MENTLGEGSTVNASVDVDQHGNDNNSDSNANAAVAGVANTDTAGEESQQQDESLKDEATVPNTRDAESEAITVTAKQQPTMQANKLDSQETPSTEESRAQNVFGQDNEDSDNLFGETESSVSNNEANTPSIPTNPVDNENNKPAIKEDSTIQDSNGDVKNMEDVKIQKEEEPENNTVIEGVKEESQPDENTKEMDEVEEDDEDDDQPMISPDNSIFGDTKSESKQLGNTSSVANTPSEIPDAHKAEQEDIIEKTESVDKKVDSGEERNEQEREIMNDHSKSANPKKTTITRVEPETFEIPQAHEIVIPSYSKWFNLEKIH... | carbon catabolite activation of transcription from RNA polymerase II promoter chromatin remodeling positive regulation of DNA-templated transcription positive regulation of mating type switching positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II chromatin; cytosol... |
cell adhesion cellular response to low-density lipoprotein particle stimulus integrin-mediated signaling pathway phagocytosis positive regulation of leukocyte adhesion to vascular endothelial cell receptor internalization | cell surface; focal adhesion; integrin complex; membrane; membrane raft | amyloid-beta binding integrin binding metal ion binding | Bos taurus | Calcium Cell adhesion Cell membrane Disease variant Disulfide bond EGF-like domain Glycoprotein Integrin Magnesium Membrane Metal-binding Phagocytosis Phosphoprotein Pyrrolidone carboxylic acid Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MLRQRPQLLL | MLRQRPQLLLLAGLLALQSVLSQECTNYKVSTCRDCIESGPGCAWCQKLNFTGQGEPDSIRCDTRAELLSKGCPADDIMEPKSLAETRDSQAGSRKQLSPQEVTLYLRPGQAVAFNVTFRRAKGYPIDLYYLMDLSYSMVDDLVNVKKLGGDLLRALNGITESGRIGFGSFVDKTVLPFVNTHPEKLRNPCPNKEKECQPPFAFRHVLKLTDNSKQFETEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKSSNEFDYPSVGQLAHKLAESNIQPIF... | cell adhesion cellular response to low-density lipoprotein particle stimulus integrin-mediated signaling pathway phagocytosis positive regulation of leukocyte adhesion to vascular endothelial cell receptor internalization cell surface; focal adhesion; integrin complex; membrane; membrane raft amyloid-beta binding integ... |
actin filament bundle assembly actin filament network formation actin filament organization formin-nucleated actin cable assembly | actin cortical patch; actin filament; actin filament bundle; cellular bud tip; cytoplasm; mating projection tip; plasma membrane | actin filament binding metal ion binding protein-macromolecule adaptor activity | Saccharomyces cerevisiae | Actin-binding Calcium Metal-binding Reference proteome Repeat | MNIVKLQRKF | MNIVKLQRKFPILTQEDLFSTIEKFRAIDLDDKGWVEKQQALEAVSKDGDATYDEARETLKHVGVDASGRVELDDYVGLVAKLRESKTGAAPQTTFNVAPNSTPIVSTAATGLQHKGKGTQAKIIVAGSQTGTTHTINEEERREFTKHINSVLAGDQDIGDLLPFPTDTFQLFDECRDGLVLSKLINDSVPDTIDTRVLNWPKKGKELNNFQASENANIVINSAKAIGCVVVNVHSEDIIEGREHLILGLIWQIIRRGLLSKIDIKLHPELYRLLEDDETLEQFLRLPPEQILLRWFNYHLKQANWNRRVTNFSKDVSDG... | actin filament bundle assembly actin filament network formation actin filament organization formin-nucleated actin cable assembly actin cortical patch; actin filament; actin filament bundle; cellular bud tip; cytoplasm; mating projection tip; plasma membrane actin filament binding metal ion binding protein-macromolecul... |
autophagy intracellular protein transport SNARE complex disassembly vacuole fusion, non-autophagic vesicle fusion with Golgi apparatus | cytosol; fungal-type vacuole membrane; SNARE complex | ATPase activator activity soluble NSF attachment protein activity syntaxin binding | Saccharomyces cerevisiae | 3D-structure Acetylation Direct protein sequencing ER-Golgi transport Isopeptide bond Membrane Protein transport Reference proteome Transport Ubl conjugation | MSDPVELLKR | MSDPVELLKRAEKKGVPSSGFMKLFSGSDSYKFEEAADLCVQAATIYRLRKELNLAGDSFLKAADYQKKAGNEDEAGNTYVEAYKCFKSGGNSVNAVDSLENAIQIFTHRGQFRRGANFKFELGEILENDLHDYAKAIDCYELAGEWYAQDQSVALSNKCFIKCADLKALDGQYIEASDIYSKLIKSSMGNRLSQWSLKDYFLKKGLCQLAATDAVAAARTLQEGQSEDPNFADSRESNFLKSLIDAVNEGDSEQLSEHCKEFDNFMRLDKWKITILNKIKESIQQQEDDLL | autophagy intracellular protein transport SNARE complex disassembly vacuole fusion, non-autophagic vesicle fusion with Golgi apparatus cytosol; fungal-type vacuole membrane; SNARE complex ATPase activator activity soluble NSF attachment protein activity syntaxin binding Saccharomyces cerevisiae 3D-structure Acetylatio... |
ascospore formation cell wall organization glucan catabolic process | ascospore wall; cell surface; extracellular region; fungal-type cell wall; fungal-type vacuole; prospore membrane | glucan exo-1,3-beta-glucosidase activity | Saccharomyces cerevisiae | Cell wall biogenesis/degradation Glycoprotein Glycosidase Hydrolase Reference proteome Secreted Signal Sporulation | MVSFRGLTTL | MVSFRGLTTLTLLFTKLVNCNPVSTKNRDSIQFIYKEKDSIYSAINNQAINEKIHGVNLGGWLVLEPYITPSLFETFRTNPYNDDGIPVDEYHFCEKLGYEKAKERLYSHWSTFYKEEDFAKIASQGFNLVRIPIGYWAFTTLSHDPYVTAEQEYFLDRAIDWARKYGLKVWIDLHGAAGSQNGFDNSGLRDSYKFLEDENLSATMKALTYILSKYSTDVYLDTVIGIELLNEPLGPVIDMERLKNLLLKPAYDYLRNKINSNQIIVIHDAFQPYHYWDGFLNDEKNEYGVIIDHHHYQVFSQVELTRKMNERIKIACQW... | ascospore formation cell wall organization glucan catabolic process ascospore wall; cell surface; extracellular region; fungal-type cell wall; fungal-type vacuole; prospore membrane glucan exo-1,3-beta-glucosidase activity Saccharomyces cerevisiae Cell wall biogenesis/degradation Glycoprotein Glycosidase Hydrolase Ref... |
fructose 2,6-bisphosphate metabolic process fructose metabolic process glucose metabolic process | cytoplasm; cytosol | 6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity | Saccharomyces cerevisiae | ATP-binding Hydrolase Nucleotide-binding Phosphoprotein Reference proteome | MGYSTISNDN | MGYSTISNDNDIKVCVIMVGLPARGKSFISQKIIRYLSWLSIKAKCFNVGNYRRDVSGNVPMDAEFFNFENTDNFKLRELAAQNAIKDIVNFFTKEDGSVAVFDATNSTRKRRKWLKDICEKNNIQPMFLESWSNDHELIINNAKDIGSTSPDYENSEPHVAEADFLERIRQYERFYEPLDPQKDKDMTFIKLVNIIEEVVINKIRTYLESRIVFYVMNIRPKPKYIWLSRHGESIYNVEKKIGGDSSLSERGFQYAKKLEQLVKESAGEINLTVWTSTLKRTQQTANYLPYKKLQWKALDELDAGVCDGMTYEEIEKEY... | fructose 2,6-bisphosphate metabolic process fructose metabolic process glucose metabolic process cytoplasm; cytosol 6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity Saccharomyces cerevisiae ATP-binding Hydrolase Nucleotide-binding Phosphoprotein Reference proteome MGYSTISN... |
mRNA 5'-splice site recognition mRNA splicing, via spliceosome | commitment complex; nucleus; spliceosomal complex; U1 snRNP; U2-type prespliceosome | U1 snRNA binding | Saccharomyces cerevisiae | 3D-structure mRNA processing mRNA splicing Nucleus Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome | MSALYFQNLP | MSALYFQNLPSRPANKENYTRLLLKHINPNNKYAINPSLPLPHNKLQISSQPLMLLDDQMGLLEVSISRSSKMTNQAFLTFVTQEEADRFLEKYTTTALKVQGRKVRMGKARTNSLLGLSIEMQKKKGNDETYNLDIKKVLKARKLKRKLRSDDICAKKFRLKRQIRRLKHKLRSRKVEEAEIDRIVKEFETRRLENMKSQQENLKQSQKPLKRAKVSNTMENPPNKVLLIQNLPSGTTEQLLSQILGNEALVEIRLVSVRNLAFVEYETVADATKIKNQLGSTYKLQNNDVTIGFAK | mRNA 5'-splice site recognition mRNA splicing, via spliceosome commitment complex; nucleus; spliceosomal complex; U1 snRNP; U2-type prespliceosome U1 snRNA binding Saccharomyces cerevisiae 3D-structure mRNA processing mRNA splicing Nucleus Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome MSALYFQNLP ... |
cellular response to oleic acid mitochondria-nucleus signaling pathway peroxisome fission positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | cytoplasm; nucleus; transcription regulator complex | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity | Saccharomyces cerevisiae | DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSSIPAGTDP | MSSIPAGTDPGSCGANFKNDRKRRDKINDRIQELLSIIPKDFFRDYYGNSGSNDTLSESTPGALGLSSKAKGTGTKDGKPNKGQILTQAVEYISHLQNQVDTQNREEVELMVKATQLAKQTGTIVNDINLENTSAEVALSRIGVGPLAATNDDSVRPPAKRLSSFEYGGYGEYGNGS | cellular response to oleic acid mitochondria-nucleus signaling pathway peroxisome fission positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoplasm; nucleus; transcription regulator complex DNA binding DNA-binding transcription factor activity, RNA polymerase I... |
Golgi to endosome transport Golgi to vacuole transport vacuole inheritance vesicle docking involved in exocytosis vesicle fusion | cytoplasm; cytoplasmic side of endosome membrane; cytosol; nucleus; vacuolar membrane | metal ion binding phosphatidylinositol-3-phosphate binding | Saccharomyces cerevisiae | Membrane Metal-binding Reference proteome Repeat Vacuole Zinc Zinc-finger | MDLENVSCPI | MDLENVSCPICLRKFDNLQALNAHLDVEHGFNDNEDSLGSNDSRLVNGKQKKARSVDSSAQKLKRSHWEKFKKGKSCCHTCGRTLNNNIGAINCRKCGKLYCRRHLPNMIKLNLSAQYDPRNGKWYNCCHDCFVTKPGYNDYGEVIDLTPEFFKVRNIKREDKNLRLLQLENRFVRLVDGLITLYNTYSRSIIHNLKMNSEMSKLERTVTPWRDDRSVLFCNICSEPFGLLLRKHHCRLCGMVVCDDANRNCSNEISIGYLMSAASDLPFEYNIQKDDLLHIPISIRLCSHCIDMLFIGRKFNKDVRMPLSGIFAKYDSM... | Golgi to endosome transport Golgi to vacuole transport vacuole inheritance vesicle docking involved in exocytosis vesicle fusion cytoplasm; cytoplasmic side of endosome membrane; cytosol; nucleus; vacuolar membrane metal ion binding phosphatidylinositol-3-phosphate binding Saccharomyces cerevisiae Membrane Metal-bindi... |
endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification | fungal-type vacuole membrane; Golgi membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain | proton-transporting ATPase activity, rotational mechanism | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Hydrogen ion transport Ion transport Membrane Reference proteome Transport Vacuole | MSGNREQVFP | MSGNREQVFPTRMTLGLMKTKLKGANQGYSLLKRKSEALTKRFRDITKRIDDAKQKMGRVMQTAAFSLAEVSYATGENIGYQVQESVSTARFKVRARQENVSGVYLSQFESYIDPEINDFRLTGLGRGGQQVQRAKEIYSRAVETLVELASLQTAFIILDEVIKVTNRRVNAIEHVIIPRTENTIAYINSELDELDREEFYRLKKVQEKKQNETAKLDAEMKLKRDRAEQDASEVAADEEPQGETLVADQEDDVIF | endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification fungal-type vacuole membrane; Golgi membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V1 domain proton-transpor... |
cellular response to anoxia | cytosol; mitochondrion; plasma membrane | FMN binding fumarate reductase (NADH) activity | Saccharomyces cerevisiae | Cytoplasm Direct protein sequencing FAD Flavoprotein NAD Oxidoreductase Phosphoprotein Reference proteome | MSLSPVVVIG | MSLSPVVVIGTGLAGLAAANELVNKYNIPVTILEKASSIGGNSIKASSGINGACTETQRHFHIEDSPRLFEDDTIKSAKGKGVQELMAKLANDSPLAIEWLKNEFDLKLDLLAQLGGHSVARTHRSSGKLPPGFEIVSALSNNLKKLAETKPELVKINLDSKVVDIHEKDGSISAVVYEDKNGEKHMVSANDVVFCSGGFGFSKEMLKEYAPELVNLPTTNGQQTTGDGQRLLQKLGADLIDMDQIQVHPTGFIDPNDRSSSWKFLAAESLRGLGGILLNPITGRRFVNELTTRDVVTAAIQKVCPQEDNRALLVMGEKM... | cellular response to anoxia cytosol; mitochondrion; plasma membrane FMN binding fumarate reductase (NADH) activity Saccharomyces cerevisiae Cytoplasm Direct protein sequencing FAD Flavoprotein NAD Oxidoreductase Phosphoprotein Reference proteome MSLSPVVVIG MSLSPVVVIGTGLAGLAAANELVNKYNIPVTILEKASSIGGNSIKASSGINGACTETQRHFH... |
nucleoside diphosphate catabolic process protein glycosylation protein N-linked glycosylation | Golgi apparatus; Golgi membrane; membrane | GDP phosphatase activity UDP phosphatase activity | Saccharomyces cerevisiae | Direct protein sequencing Glycoprotein Golgi apparatus Hydrolase Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix | MAPIFRNYRF | MAPIFRNYRFAIGAFAVIMLILLIKTSSIGPPSIARTVTPNASIPKTPEDISILPVNDEPGYLQDSKTEQNYPELADAVKSQTSQTCSEEHKYVIMIDAGSTGSRVHIYKFDVCTSPPTLLDEKFDMLEPGLSSFDTDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNT... | nucleoside diphosphate catabolic process protein glycosylation protein N-linked glycosylation Golgi apparatus; Golgi membrane; membrane GDP phosphatase activity UDP phosphatase activity Saccharomyces cerevisiae Direct protein sequencing Glycoprotein Golgi apparatus Hydrolase Membrane Reference proteome Signal-anchor T... |
carbohydrate metabolic process cell wall chitin metabolic process fungal-type cell wall organization | cellular bud neck septin ring; extracellular region; fungal-type cell wall; side of membrane | glycosyltransferase activity hydrolase activity, hydrolyzing O-glycosyl compounds | Saccharomyces cerevisiae | Cell wall Cell wall biogenesis/degradation Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Reference proteome Secreted Signal | MAIVNSWLIC | MAIVNSWLICLVSIFSFVVRVEAATFCNATQACPEDKPCCSQYGECGTGQYCLNNCDVRYSFSHDSCMPVPICKSSSTKFKDYSSKLGNANTFLGNVSEADWLYTGDVLDYDDEESLILAMPKNSGGTVLSSTRAVWYGKVSARIKTSHLAGVVTGFILYSGAGDELDYEFVGADLETAQTNFYWESVLNYTNSANISTTDTFENYHTYELDWHEDYVTWSIDGVVGRTLYKNETYNATTQKYQYPQTPSKVDISIWPGGNSTNAPGTIAWSGGEINWDASDISNPGYYYAIVNEVNITCYDPPSDTKKNGTSAYVYTSS... | carbohydrate metabolic process cell wall chitin metabolic process fungal-type cell wall organization cellular bud neck septin ring; extracellular region; fungal-type cell wall; side of membrane glycosyltransferase activity hydrolase activity, hydrolyzing O-glycosyl compounds Saccharomyces cerevisiae Cell wall Cell wal... |
L-methionine salvage from methylthioadenosine L-methionine salvage from S-adenosylmethionine | cytoplasm; nucleus | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity acireductone synthase activity magnesium ion binding | Saccharomyces cerevisiae | 3D-structure Amino-acid biosynthesis Cytoplasm Hydrolase Magnesium Metal-binding Methionine biosynthesis Nucleus Reference proteome | MGDNYSTYLL | MGDNYSTYLLDIEGTVCPISFVKETLFPYFTNKVPQLVQQDTRDSPVSNILSQFHIDNKEQLQAHILELVAKDVKDPILKQLQGYVWAHGYESGQIKAPVYADAIDFIKRKKRVFIYSSGSVKAQKLLFGYVQDPNAPAHDSLDLNSYIDGYFDINTSGKKTETQSYANILRDIGAKASEVLFLSDNPLELDAAAGVGIATGLASRPGNAPVPDGQKYQVYKNFETL | L-methionine salvage from methylthioadenosine L-methionine salvage from S-adenosylmethionine cytoplasm; nucleus 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity acireductone synthase activity magnesium ion binding Saccharomyces cerevisiae ... |
negative regulation of transcription by RNA polymerase II nucleotide-excision repair, DNA damage recognition proteasome-mediated ubiquitin-dependent protein catabolic process protein deglycosylation ubiquitin-dependent ERAD pathway ubiquitin-dependent glycoprotein ERAD pathway | cytoplasm; cytosol; mitochondrion; nucleoplasm; nucleotide-excision repair factor 2 complex; PNGase complex | damaged DNA binding polyubiquitin modification-dependent protein binding proteasome binding protein-macromolecule adaptor activity ubiquitin binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm DNA damage DNA repair Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Ubl conjugation Ubl conjugation pathway | MVSLTFKNFK | MVSLTFKNFKKEKVPLDLEPSNTILETKTKLAQSISCEESQIKLIYSGKVLQDSKTVSECGLKDGDQVVFMVSQKKSTKTKVTEPPIAPESATTPGRENSTEASPSTDASAAPAATAPEGSQPQEEQTATTERTESASTPGFVVGTERNETIERIMEMGYQREEVERALRAAFNNPDRAVEYLLMGIPENLRQPEPQQQTAAAAEQPSTAATTAEQPAEDDLFAQAAQGGNASSGALGTTGGATDAAQGGPPGSIGLTVEDLLSLRQVVSGNPEALAPLLENISARYPQLREHIMANPEVFVSMLLEAVGDNMQDVMEGA... | negative regulation of transcription by RNA polymerase II nucleotide-excision repair, DNA damage recognition proteasome-mediated ubiquitin-dependent protein catabolic process protein deglycosylation ubiquitin-dependent ERAD pathway ubiquitin-dependent glycoprotein ERAD pathway cytoplasm; cytosol; mitochondrion; nucleop... |
cell wall mannoprotein biosynthetic process protein N-linked glycosylation | endoplasmic reticulum membrane; Golgi cis cisterna; mannan polymerase complex | alpha-1,6-mannosyltransferase activity | Saccharomyces cerevisiae | Direct protein sequencing Endoplasmic reticulum Golgi apparatus Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix | MKYNNRKLSF | MKYNNRKLSFNPTTVSIAGTLLTVFFLTRLVLSFFSISLFQLVTFQGIFKPYVPDFKNTPSVEFYDLRNYQGNKDGWQQGDRILFCVPLRDASEHLPMFFNHLNTMTYPHNLIDLSFLVSDSSDNTMGVLLSNLQMAQSQQDKSKRFGNIEIYEKDFGQIIGQSFSDRHGFGAQGPRRKLMARARNWLGSVALKPYHSWVYWRDVDVETIPTTIMEDLMHHDKDVIVPNVWRPLPDWLGNIQPYDLNSWKESEGGLQLADSLDEDAVIVEGYPEYATWRPHLAYMRDPNGNPEDEMELDGIGGVSILAKAKVFRTGSHFP... | cell wall mannoprotein biosynthetic process protein N-linked glycosylation endoplasmic reticulum membrane; Golgi cis cisterna; mannan polymerase complex alpha-1,6-mannosyltransferase activity Saccharomyces cerevisiae Direct protein sequencing Endoplasmic reticulum Golgi apparatus Membrane Reference proteome Signal-anc... |
DNA damage checkpoint signaling DNA repair mitotic DNA replication checkpoint signaling nucleotide-excision repair reciprocal meiotic recombination | nucleus; Rad17 RFC-like complex | ATP binding chromatin binding DNA clamp loader activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle DNA damage Nucleotide-binding Nucleus Phosphoprotein Reference proteome | MDSTNLNKRP | MDSTNLNKRPLLQYSLSSLGSQITKWSSSRPTSPVRKARSTENDFLSKQDTSSILPSINDDGGEQWYEKFKPNCLEQVAIHKRKLKDVQEALDAMFLPNAKHRILLLSGPSGCSKSTVIKELSKILVPKYRQNSNGTSFRSTPNEHKVTEFRGDCIVNDLPQMESFSEFLKGARYLVMSNLSLILIEDLPNVFHIDTRRRFQQLILQWLYSSEPLLPPLVICITECEIPENDNNYRKFGIDYTFSAETIMNKEILMHPRLKRIKFNPINSTLLKKHLKFICVQNMKMLKEKNKWNKRQEVIDYIAQETGDIRSAITTLQF... | DNA damage checkpoint signaling DNA repair mitotic DNA replication checkpoint signaling nucleotide-excision repair reciprocal meiotic recombination nucleus; Rad17 RFC-like complex ATP binding chromatin binding DNA clamp loader activity Saccharomyces cerevisiae 3D-structure ATP-binding Cell cycle DNA damage Nucleotide-... |
actin cytoskeleton organization cellular response to oxidative stress intracellular iron ion homeostasis iron-sulfur cluster assembly negative regulation of transcription regulatory region DNA binding | cytoplasm; cytosol; iron-sulfur cluster assembly complex; nucleus | 2 iron, 2 sulfur cluster binding disulfide oxidoreductase activity glutathione transferase activity metal ion binding RNA polymerase II-specific DNA-binding transcription factor binding | Saccharomyces cerevisiae | 2Fe-2S Iron Iron-sulfur Metal-binding Redox-active center Reference proteome | MTVVEIKSQD | MTVVEIKSQDQFTQLTTTNAANKLIVLYFKAQWADPCKTMSQVLEAVSEKVRQEDVRFLSIDADEHPEISDLFEIAAVPYFVFIQNGTIVKEISAADPKEFVKSLEILSNASASLANNAKGPKSTSDEESSGSSDDEEDETEEEINARLVKLVQAAPVMLFMKGSPSEPKCGFSRQLVGILREHQIRFGFFDILRDENVRQSLKKFSDWPTFPQLYINGEFQGGLDIIKESIEEDPEYFQHALQ | actin cytoskeleton organization cellular response to oxidative stress intracellular iron ion homeostasis iron-sulfur cluster assembly negative regulation of transcription regulatory region DNA binding cytoplasm; cytosol; iron-sulfur cluster assembly complex; nucleus 2 iron, 2 sulfur cluster binding disulfide oxidoreduc... |
methylation | cytosol | trans-aconitate 3-methyltransferase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Methyltransferase Reference proteome S-adenosyl-L-methionine Transferase | MSTFSASDFN | MSTFSASDFNSERYSSSRPSYPSDFYKMIDEYHDGERKLLVDVGCGPGTATLQMAQELKPFEQIIGSDLSATMIKTAEVIKEGSPDTYKNVSFKISSSDDFKFLGADSVDKQKIDMITAVECAHWFDFEKFQRSAYANLRKDGTIAIWGYADPIFPDYPEFDDLMIEVPYGKQGLGPYWEQPGRSRLRNMLKDSHLDPELFHDIQVSYFCAEDVRDKVKLHQHTKKPLLIRKQVTLVEFADYVRTWSAYHQWKQDPKNKDKEDVADWFIKESLRRRPELSTNTKIEVVWNTFYKLGKRV | methylation cytosol trans-aconitate 3-methyltransferase activity Saccharomyces cerevisiae 3D-structure Acetylation Cytoplasm Methyltransferase Reference proteome S-adenosyl-L-methionine Transferase MSTFSASDFN MSTFSASDFNSERYSSSRPSYPSDFYKMIDEYHDGERKLLVDVGCGPGTATLQMAQELKPFEQIIGSDLSATMIKTAEVIKEGSPDTYKNVSFKISSSDDFKFLGADSVD... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway antibacterial humoral response antifungal humoral response antimicrobial humoral immune response mediated by antimicrobial peptide defense response to Gram-negative bacterium defense response to Gram-positive bacterium epinephrine secretion innat... | extracellular region; neuron projection; neuronal cell body | hormone activity neuropeptide hormone activity peptide hormone receptor binding signaling receptor binding | Mus musculus | Amidation Cleavage on pair of basic residues Direct protein sequencing Glycoprotein Hormone Phosphoprotein Reference proteome Secreted Signal | MEARSKPQFL | MEARSKPQFLAFLILFSVLFSQSLAWPLFGPPSVVRLDDRMPFEGAGDPDQVSLKADSDILQNPLAENGTPYYDVSRNARHADGVFTSDYSRLLGQISAKKYLESLIGKRISSSISEDPVPIKRHSDAVFTDNYTRLRKQMAVKKYLNSILNGKRSSEGDSADFLEELEK | adenylate cyclase-activating G protein-coupled receptor signaling pathway antibacterial humoral response antifungal humoral response antimicrobial humoral immune response mediated by antimicrobial peptide defense response to Gram-negative bacterium defense response to Gram-positive bacterium epinephrine secretion innat... |
carbohydrate metabolic process dephosphorylation DNA repair glycolate biosynthetic process | cytosol | chloride ion binding magnesium ion binding phosphoglycolate phosphatase activity | Escherichia coli | Carbohydrate metabolism Chloride Hydrolase Magnesium Metal-binding Reference proteome | MNKFEDIRGV | MNKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEERVITWIGNGADVLMERALTWARQERATQRKTMGKPPVDDDIPAEEQVRILRKLFDRYYGEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGGDDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGEAIDLSQPDVIYQSINDLLPALGLPHSENQESKND | carbohydrate metabolic process dephosphorylation DNA repair glycolate biosynthetic process cytosol chloride ion binding magnesium ion binding phosphoglycolate phosphatase activity Escherichia coli Carbohydrate metabolism Chloride Hydrolase Magnesium Metal-binding Reference proteome MNKFEDIRGV MNKFEDIRGVAFDLDGTLVDSAPGLA... |
plasma membrane acetate transport sodium ion transport tellurite transport | plasma membrane | acetate transmembrane transporter activity glycolate transmembrane transporter activity symporter activity tellurite transmembrane transporter activity | Escherichia coli | Cell inner membrane Cell membrane Ion transport Membrane Reference proteome Sodium Sodium transport Symport Transmembrane Transmembrane helix Transport | MKRVLTALAA | MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI... | plasma membrane acetate transport sodium ion transport tellurite transport plasma membrane acetate transmembrane transporter activity glycolate transmembrane transporter activity symporter activity tellurite transmembrane transporter activity Escherichia coli Cell inner membrane Cell membrane Ion transport Membrane Ref... |
dodecyl sulfate metabolic process | outer membrane-bounded periplasmic space | linear primary-alkylsulfatase activity metal ion binding protein dimerization activity | Escherichia coli | 3D-structure Hydrolase Metal-binding Periplasm Reference proteome Signal Zinc | MNNSRLFRLS | MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVNQNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKVYYRADDYKFDINAAAPETVNPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAALDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISENVLAGNIMSRRALYSYGLLLPHNAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMIIDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFY... | dodecyl sulfate metabolic process outer membrane-bounded periplasmic space linear primary-alkylsulfatase activity metal ion binding protein dimerization activity Escherichia coli 3D-structure Hydrolase Metal-binding Periplasm Reference proteome Signal Zinc MNNSRLFRLS MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVNQNYAKSLP... |
carbohydrate metabolic process D-allose catabolic process pentose-phosphate shunt, non-oxidative branch | cytosol | allulose 6-phosphate 3-epimerase activity D-ribulose-phosphate 3-epimerase activity metal ion binding | Escherichia coli | 3D-structure Carbohydrate metabolism Cobalt Isomerase Manganese Metal-binding Reference proteome Zinc | MKISPSLMCM | MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTLSPFFVSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEIRRHDMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAWREREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQILAAKSEVQPHAKTA | carbohydrate metabolic process D-allose catabolic process pentose-phosphate shunt, non-oxidative branch cytosol allulose 6-phosphate 3-epimerase activity D-ribulose-phosphate 3-epimerase activity metal ion binding Escherichia coli 3D-structure Carbohydrate metabolism Cobalt Isomerase Manganese Metal-binding Reference p... |
basic amino acid transport monoatomic ion transport proteolysis | cell outer membrane; outer membrane; pore complex | porin activity serine-type peptidase activity | Pseudomonas aeruginosa | 3D-structure Cell outer membrane Direct protein sequencing Hydrolase Ion transport Membrane Porin Protease Reference proteome Serine protease Signal Transmembrane Transmembrane beta strand Transport | MKVMKWSAIA | MKVMKWSAIALAVSAGSTQFAVADAFVSDQAEAKGFIEDSSLDLLLRNYYFNRDGKSGSGDRVDWTQGFLTTYESGFTQGTVGFGVDAFGYLGLKLDGTSDKTGTGNLPVMNDGKPRDDYSRAGGAVKVRISKTMLKWGEMQPTAPVFAAGGSRLFPQTATGFQLQSSEFEGLDLEAGHFTEGKEPTTVKSRGELYATYAGETAKSADFIGGRYAITDNLSASLYGAELEDIYRQYYLNSNYTIPLASDQSLGFDFNIYRTNDEGKAKAGDISNTTWSLAAAYTLDAHTFTLAYQKVHGDQPFDYIGFGRNGSGAGGDSI... | basic amino acid transport monoatomic ion transport proteolysis cell outer membrane; outer membrane; pore complex porin activity serine-type peptidase activity Pseudomonas aeruginosa 3D-structure Cell outer membrane Direct protein sequencing Hydrolase Ion transport Membrane Porin Protease Reference proteome Serine prot... |
acetylcholine biosynthetic process adult walking behavior antral ovarian follicle growth chemical synaptic transmission dendrite development establishment of synaptic specificity at neuromuscular junction memory muscle organ development neuromuscular synaptic transmission neuron differentiation response to ethanol resp... | axon; cytoplasm; neuron projection; neuronal cell body; synapse | choline binding choline O-acetyltransferase activity | Rattus norvegicus | 3D-structure Acyltransferase Neurotransmitter biosynthesis Phosphoprotein Reference proteome Transferase | MPILEKAPQK | MPILEKAPQKMPVKASSWEELDLPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLDSHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLLKDSTNRDSLDMIERCICLVCLDGPGTGELSDTHRALQLLHGGGCSLNGANRWYDKSLQF... | acetylcholine biosynthetic process adult walking behavior antral ovarian follicle growth chemical synaptic transmission dendrite development establishment of synaptic specificity at neuromuscular junction memory muscle organ development neuromuscular synaptic transmission neuron differentiation response to ethanol resp... |
autophagy protein phosphorylation regulation of autophagy | cytoplasm | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Caenorhabditis elegans | Alternative splicing ATP-binding Autophagy Cytoplasm Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MAVSPHKTYP | MAVSPHKTYPIVITHGEKYTLFNDESIGKGAYSEVYRGRTESGRLVAVKTACKKLEVAAIGIEIEILKKLKGASNIVQYFGSNHTKMAPGSVTSETISFAMEYASSSLEAEMRRPKNHRGLSSNALIDLVVDCSMALSALREHNIAHRDIKHMNILLFPGTPTRGRRSTHLFKLCDMGCSKSLSENSSHEMRTLVGTPNLLHPFLAHEMVDPLMAQNRHNWKTKSAYTSEQCDLWALGCTLYFCATGKFPFEHERNNKSLYHKAVVALTQNPDAIAMVLVQKGRDPGRRTDIFEFQPVTELPAKFTRYPKWLVSTMTCLL... | autophagy protein phosphorylation regulation of autophagy cytoplasm ATP binding protein serine kinase activity protein serine/threonine kinase activity Caenorhabditis elegansAlternative splicing ATP-binding Autophagy Cytoplasm Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase MAVS... |
astral microtubule organization attachment of meiotic spindle microtubules to kinetochore cytoplasmic streaming establishment of mitotic spindle localization meiotic chromosome separation meiotic spindle midzone assembly meiotic spindle organization microtubule polymerization mitotic cytokinesis mitotic sister chromati... | basal cortex; centrosome; cytoplasm; cytoplasmic microtubule; cytosol; kinetochore; microtubule organizing center; mitotic spindle; nucleus; spindle microtubule; spindle midzone | microtubule binding | Caenorhabditis elegans | Cell cycle Cell division Centromere Chromosome Cytoplasm Cytoskeleton Kinetochore Meiosis Microtubule Mitosis Reference proteome | MSRVISRSTP | MSRVISRSTPGGTCIVSKDDFLKSFEEVPKMEISSPSDFKEKLDQTIETLSKGQEDWNKRMNKLKQIRSMVVHGEDVIGREQLLSQLVRLTDCLDLSVKDLRSQILREAAITCGFLFKRFGTDVRQIAERCLPSAFAQVAVSTKVMATCGAVLTLFIVEFIQTKQIFTCIASYSTSKDKNQRRQLCALLEIVLEHWNEKIKRTVLPQIGELIKAAICDADPETRVAGRKAFSKLDALHSTEADKLFASVDSSKQKMLRASDAASSSTSINSERGTAPFRSKLSAGSIGGIRNAPNISSKFLAQRSASAIDTKQVTRMATS... | astral microtubule organization attachment of meiotic spindle microtubules to kinetochore cytoplasmic streaming establishment of mitotic spindle localization meiotic chromosome separation meiotic spindle midzone assembly meiotic spindle organization microtubule polymerization mitotic cytokinesis mitotic sister chromati... |
cell-cell signaling cellular response to estradiol stimulus cellular response to glucocorticoid stimulus cerebellum development forebrain development G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger hormone-mediated apoptotic signaling pathway negative regulation of cell popul... | ciliary membrane; cilium; neuron projection; non-motile cilium; plasma membrane | G protein-coupled receptor activity neuropeptide binding signaling receptor binding somatostatin receptor activity | Homo sapiens | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDMLHPSSVS | MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRF... | cell-cell signaling cellular response to estradiol stimulus cellular response to glucocorticoid stimulus cerebellum development forebrain development G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger hormone-mediated apoptotic signaling pathway negative regulation of cell popul... |
L-phenylalanine catabolic process tyrosine catabolic process | cytosol; endoplasmic reticulum membrane; extracellular exosome; Golgi membrane | 4-hydroxyphenylpyruvate dioxygenase activity metal ion binding protein homodimerization activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Dioxygenase Disease variant Endoplasmic reticulum Golgi apparatus Intellectual disability Iron Membrane Metal-binding Oxidoreductase Phenylalanine catabolism Phosphoprotein Reference proteome Repeat Tyrosine catabolism | MTTYSDKGAK | MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEEL... | L-phenylalanine catabolic process tyrosine catabolic process cytosol; endoplasmic reticulum membrane; extracellular exosome; Golgi membrane 4-hydroxyphenylpyruvate dioxygenase activity metal ion binding protein homodimerization activity Homo sapiens 3D-structure Acetylation Alternative splicing Cytoplasm Dioxygenase Di... |
L-phenylalanine catabolic process tyrosine catabolic process | endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane | 4-hydroxyphenylpyruvate dioxygenase activity iron ion binding protein homodimerization activity | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Dioxygenase Endoplasmic reticulum Golgi apparatus Iron Membrane Metal-binding Oxidoreductase Phenylalanine catabolism Phosphoprotein Reference proteome Repeat Tyrosine catabolism | MTTYSNKGPK | MTTYSNKGPKPERGRFLHFHSVTFWVGNAKQAASFYCNKMGFEPLAYKGLETGSREVVSHVIKQGKIVFVLCSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCEHIVQKARERGAKIVREPWVEEDKFGKVKFAVLQTYGDTTHTLVEKINYTGRFLPGFEAPTYKDTLLPKLPSCNLEIIDHIVGNQPDQEMESASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGRKKSQIQEYVDYNGGAGVQHIALRTEDIITTIRHLRERGMEFLAVPSSYYRLLRENLKTSKIQVKENMDVLEEL... | L-phenylalanine catabolic process tyrosine catabolic process endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane 4-hydroxyphenylpyruvate dioxygenase activity iron ion binding protein homodimerization activity Rattus norvegicus 3D-structure Acetylation Cytoplasm Dioxygenase Endoplasmic... |
acetylcholine biosynthetic process neuromuscular synaptic transmission | cytoplasm; cytosol; excitatory synapse; neuron projection; neuronal cell body; organelle membrane; plasma membrane; synapse | choline O-acetyltransferase activity | Caenorhabditis elegans | Acyltransferase Neurotransmitter biosynthesis Reference proteome Transferase | MEKEKVDELP | MEKEKVDELPPNDNWYETALPKPPVPSLEATLDRYLEYAAVVAVGQKASLATTHDAAHKFVRQATPLQEQLLEIAEKSPNWATKFWLPEMYMRVRMPTPVNSNPGYIFPKVKFETKEDHIKYTALLTRGLLEYKNLIDTKQVCREKSTGAQKLQMCMEQYDRVLSCYREPGVGEDTQIRKQKTNDGNEHVLVMCRNQTFLLHSRINGALVSYADVEYQLAQIEEISKINQNNTANIGASGVGPRDNAALFWQDMLTVEQNSKSYEWVKSALFVVCLDMEDPIDYGKNDTMSISEKEKEFVARGYSTLTGHGSSKFGLNRW... | acetylcholine biosynthetic process neuromuscular synaptic transmission cytoplasm; cytosol; excitatory synapse; neuron projection; neuronal cell body; organelle membrane; plasma membrane; synapse choline O-acetyltransferase activity Caenorhabditis elegansAcyltransferase Neurotransmitter biosynthesis Reference proteome T... |
bone mineralization brain development cartilage development dermatome development heart development learning limb development neural tube development ossification positive regulation of cell division positive regulation of cell population proliferation regulation of endothelial cell migration sclerotome development ski... | extracellular region; extracellular space | chondroitin sulfate binding growth factor activity heparin binding | Gallus gallus | Direct protein sequencing Disulfide bond Growth factor Heparin-binding Mitogen Reference proteome Secreted Signal | MPQQQQQRRM | MPQQQQQRRMFTAALLALVFILAAVSTTEAGKKEKPEKKAKKSDCGEWQWSVCVPTNGDCGLGTREGTRTGAECKQTTKTQKCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGNLKRALHNADCQKTVTISKPCGKLTKPKPQESKKKKKEGKKQEKMLD | bone mineralization brain development cartilage development dermatome development heart development learning limb development neural tube development ossification positive regulation of cell division positive regulation of cell population proliferation regulation of endothelial cell migration sclerotome development ski... |
nonfunctional rRNA decay nuclear-transcribed mRNA catabolic process, no-go decay positive regulation of translation positive regulation of translational initiation rescue of stalled ribosome ribosome disassembly translation | cytoplasm; cytosol; Dom34-Hbs1 complex | GTP binding GTPase activity translation elongation factor activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Elongation factor GTP-binding Hydrolase Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome Translation regulation | MAYSDYSDGA | MAYSDYSDGADDMPDFHDEGEFDDYLNDDEYDLMNEVFPTLKAQLQDYQGWDNLSLKLALFDNNFDLESTLAELKKTLKKKKTPKKPIAAANGSANVTQKLANISISQQRPNDRLPDWLDEEESEGERNGEEANDEKTVQRYYKTTVPTKPKKPHDISAFVKSALPHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRESETMGKSSFKFAWIMDQTNEERERGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDW... | nonfunctional rRNA decay nuclear-transcribed mRNA catabolic process, no-go decay positive regulation of translation positive regulation of translational initiation rescue of stalled ribosome ribosome disassembly translation cytoplasm; cytosol; Dom34-Hbs1 complex GTP binding GTPase activity translation elongation factor... |
amino acid catabolic process to alcohol via Ehrlich pathway ethanol oxidation formaldehyde catabolic process furaldehyde metabolic process | cytoplasm; cytosol; mitochondrion | alcohol dehydrogenase (NAD+) activity alcohol dehydrogenase activity, zinc-dependent hydroxymethylfurfural reductase (NADH) activity S-(hydroxymethyl)glutathione dehydrogenase activity S-(hydroxymethyl)glutathione dehydrogenase NAD activity S-(hydroxymethyl)glutathione dehydrogenase NADP activity zinc ion binding | Saccharomyces cerevisiae | Acetylation Cytoplasm Direct protein sequencing Metal-binding Mitochondrion NAD Oxidoreductase Reference proteome Zinc | MSAATVGKPI | MSAATVGKPIKCIAAVAYDAKKPLSVEEITVDAPKAHEVRIKIEYTAVCHTDAYTLSGSDPEGLFPCVLGHEGAGIVESVGDDVITVKPGDHVIALYTAECGKCKFCTSGKTNLCGAVRATQGKGVMPDGTTRFHNAKGEDIYHFMGCSTFSEYTVVADVSVVAIDPKAPLDAACLLGCGVTTGFGAALKTANVQKGDTVAVFGCGTVGLSVIQGAKLRGASKIIAIDINNKKKQYCSQFGATDFVNPKEDLAKDQTIVEKLIEMTDGGLDFTFDCTGNTKIMRDALEACHKGWGQSIIIGVAAAGEEISTRPFQLVTGR... | amino acid catabolic process to alcohol via Ehrlich pathway ethanol oxidation formaldehyde catabolic process furaldehyde metabolic process cytoplasm; cytosol; mitochondrion alcohol dehydrogenase (NAD+) activity alcohol dehydrogenase activity, zinc-dependent hydroxymethylfurfural reductase (NADH) activity S-(hydroxymeth... |
positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II RNA polymerase II preinitiation complex assembly transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter | cytoplasm; nucleus; transcription factor TFIIA complex | RNA polymerase II core promoter sequence-specific DNA binding TBP-class protein binding transcription coregulator activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Nucleus Reference proteome Transcription | MSNAEASRVY | MSNAEASRVYEIIVESVVNEVREDFENAGIDEQTLQDLKNIWQKKLTETKVTTFSWDNQFNEGNINGVQNDLNFNLATPGVNSSEFNIKEENTGNEGLILPNINSNNNIPHSGETNINTNTVEATNNSGATLNTNTSGNTNADVTSQPKIEVKPEIELTINNANITTVENIDDESEKKDDEEKEEDVEKTRKEKEQIEQVKLQAKKEKRSALLDTDEVGSELDDSDDDYLISEGEEDGPDENLMLCLYDKVTRTKARWKCSLKDGVVTINRNDYTFQKAQVEAEWV | positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II RNA polymerase II preinitiation complex assembly transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter cytoplasm; nucleus; transcription factor TFIIA complex... |
positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II RNA polymerase II preinitiation complex assembly transcription initiation at RNA polymerase II promoter | cytoplasm; nucleus; transcription factor TFIIA complex | RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II general transcription initiation factor activity TBP-class protein binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MAVPGYYELY | MAVPGYYELYRRSTIGNSLVDALDTLISDGRIEASLAMRVLETFDKVVAETLKDNTQSKLTVKGNLDTYGFCDDVWTFIVKNCQVTVEDSHRDASQNGSGDSQSVISVDKLRIVACNSKKSE | positive regulation of transcription by RNA polymerase II positive regulation of transcription initiation by RNA polymerase II RNA polymerase II preinitiation complex assembly transcription initiation at RNA polymerase II promoter cytoplasm; nucleus; transcription factor TFIIA complex RNA polymerase II core promoter se... |
DNA repair nucleotide-excision repair transcription by RNA polymerase I transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter | cytosol; nucleotide-excision repair factor 3 complex; nucleus; transcription factor TFIIH core complex; transcription factor TFIIH holo complex | phosphatidylinositol-3-phosphate binding phosphatidylinositol-5-phosphate binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing DNA damage DNA repair Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MSHSGAAIFE | MSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDADIYEEKRRREESAQHTETPMSSSSVTAGTPTPHLDTPQLNNGAPLINTAKLDDSLSKEKLLTNLKLQQSLLKGNKVLMKVFQETVINAGLPPSEFWSTRIPLLRAFALSTSQKVGPYNVLSTIKPVASSENKVNVNLSREKILNIFENYPIVKKAYTDNVPKNFKEPEFWARFFSSKLFRKLRGEKIMQNDRGDVIIDRYLTLDQE... | DNA repair nucleotide-excision repair transcription by RNA polymerase I transcription by RNA polymerase II transcription initiation at RNA polymerase II promoter cytosol; nucleotide-excision repair factor 3 complex; nucleus; transcription factor TFIIH core complex; transcription factor TFIIH holo complex phosphatidylin... |
DNA repair hormone-mediated signaling pathway nucleotide-excision repair positive regulation of DNA-templated transcription regulation of cyclin-dependent protein serine/threonine kinase activity transcription by RNA polymerase I transcription by RNA polymerase II | nucleoplasm; transcription factor TFIIH core complex; transcription factor TFIIH holo complex | chromatin binding nuclear thyroid hormone receptor binding | Homo sapiens | 3D-structure Acetylation Alternative splicing DNA damage DNA repair Host-virus interaction Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MATSSEEVLL | MATSSEEVLLIVKKVRQKKQDGALYLMAERIAWAPEGKDRFTISHMYADIKCQKISPEGKAKIQLQLVLHAGDTTNFHFSNESTAVKERDAVKDLLQQLLPKFKRKANKELEEKNRMLQEDPVLFQLYKDLVVSQVISAEEFWANRLNVNATDSSSTSNHKQDVGISAAFLADVRPQTDGCNGLRYNLTSDIIESIFRTYPAVKMKYAENVPHNMTEKEFWTRFFQSHYFHRDRLNTGSKDLFAECAKIDEKGLKTMVSLGVKNPLLDLTALEDKPLDEGYGISSVPSASNSKSIKENSNAAIIKRFNHHSAMVLAAGLR... | DNA repair hormone-mediated signaling pathway nucleotide-excision repair positive regulation of DNA-templated transcription regulation of cyclin-dependent protein serine/threonine kinase activity transcription by RNA polymerase I transcription by RNA polymerase II nucleoplasm; transcription factor TFIIH core complex; t... |
7-methylguanosine mRNA capping | cytosol; mRNA cap binding complex; nucleus | mRNA 5'-cap (guanine-N7-)-methyltransferase activity RNA binding | Saccharomyces cerevisiae | Methyltransferase mRNA capping mRNA processing Nucleus Reference proteome RNA-binding S-adenosyl-L-methionine Transferase | MSTKPEKPIW | MSTKPEKPIWMSQEDYDRQYGSITGDESSTVSKKDSKVTANAPGDGNGSLPVLQSSSILTSKVSDLPIEAESGFKIQKRRHERYDQEERLRKQRAQKLREEQLKRHEIEMTANRSINVDQIVREHYNERTIIANRAKRNLSPIIKLRNFNNAIKYMLIDKYTKPGDVVLELGCGKGGDLRKYGAAGISQFIGIDISNASIQEAHKRYRSMRNLDYQVVLITGDCFGESLGVAVEPFPDCRFPCDIVSTQFCLHYAFETEEKARRALLNVAKSLKIGGHFFGTIPDSEFIRYKLNKFPKEVEKPSWGNSIYKVTFENNSYQ... | 7-methylguanosine mRNA capping cytosol; mRNA cap binding complex; nucleus mRNA 5'-cap (guanine-N7-)-methyltransferase activity RNA binding Saccharomyces cerevisiae Methyltransferase mRNA capping mRNA processing Nucleus Reference proteome RNA-binding S-adenosyl-L-methionine Transferase MSTKPEKPIW MSTKPEKPIWMSQEDYDRQYGS... |
CDP-diacylglycerol biosynthetic process phospholipid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane | glycerol-3-phosphate O-acyltransferase activity glycerone-phosphate O-acyltransferase activity sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity | Saccharomyces cerevisiae | Acyltransferase Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Transmembrane Transmembrane helix | MPAPKLTEKF | MPAPKLTEKFASSKSTQKTTNYSSIEAKSVKTSADQAYIYQEPSATKKILYSIATWLLYNIFHCFFREIRGRGSFKVPQQGPVIFVAAPHANQFVDPVILMGEVKKSVNRRVSFLIAESSLKQPPIGFLASFFMAIGVVRPQDNLKPAEGTIRVDPTDYKRVIGHDTHFLTDCMPKGLIGLPKSMGFGEIQSIESDTSLTLRKEFKMAKPEIKTALLTGTTYKYAAKVDQSCVYHRVFEHLAHNNCIGIFPEGGSHDRTNLLPLKAGVAIMALGCMDKHPDVNVKIVPCGMNYFHPHKFRSRAVVEFGDPIEIPKELVAK... | CDP-diacylglycerol biosynthetic process phospholipid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane glycerol-3-phosphate O-acyltransferase activity glycerone-phosphate O-acyltransferase activity sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity Saccharomyces cerevisiae Acylt... |
DNA damage response intracellular signal transduction mitotic cell cycle phosphorylation | cytoplasm; nucleus | ATP binding histone H3T3 kinase activity protein kinase activity protein serine kinase activity | Saccharomyces cerevisiae | ATP-binding Cell cycle DNA damage Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MNFDAVADQQ | MNFDAVADQQMTDRRYFALEVAESDDADSSLNSSSMGSPAVDVGRKVYKITSHKGSAEDESQSFFTSSDSPTSKTRPVGKTIENDDYYGKRSSTGSSLKQLFNKININDTAHSSNKENVSQSVLSENKLLSPSKRLSKQGLTKVTNSKFRTPLRPISNQSTLSRDEPVKDFRSLKFRSGSDFKCWGDEKTSSHVHSSSVNSVNSFTSTTSSSKWKFWKNDNLLSRSLSSRSVNDQDPNFVQPKPTNSLQKKSSISSFHNSIFGGGKHTEKKRNSGFIMPDHQSTKELNHKHSSSNLSFRSLKHKTSHSSLNKLKVRRKGN... | DNA damage response intracellular signal transduction mitotic cell cycle phosphorylation cytoplasm; nucleus ATP binding histone H3T3 kinase activity protein kinase activity protein serine kinase activity Saccharomyces cerevisiae ATP-binding Cell cycle DNA damage Kinase Nucleotide-binding Phosphoprotein Reference prote... |
copper ion import intracellular iron ion homeostasis iron ion transport | plasma membrane | ferric-chelate reductase (NADPH) activity ferric-chelate reductase activity metal ion binding | Saccharomyces cerevisiae | Cell membrane Copper Copper transport Electron transport FAD Flavoprotein Glycoprotein Heme Ion transport Iron Iron transport Membrane Metal-binding NADP Oxidoreductase Reference proteome Signal Transmembrane Transmembrane helix Transport | MVRTRVLFCL | MVRTRVLFCLFISFFATVQSSATLISTSCISQAALYQFGCSSKSKSCYCKNINWLGSVTACAYENSKSNKTLDSALMKLASQCSSIKVYTLEDMKNIYLNASNYLRAPEKSDKKTVVSQPLMANETAYHYYYEENYGIHLNLMRSQWCAWGLVFFWVAVLTAATILNILKRVFGKNIMANSVKKSLIYPSVYKDYNERTFYLWKRLPFNFTTRGKGLVVLIFVILTILSLSFGHNIKLPHPYDRPRWRRSMAFVSRRADLMAIALFPVVYLFGIRNNPFIPITGLSFSTFNFYHKWSAYVCFMLAVVHSIVMTASGVKRG... | copper ion import intracellular iron ion homeostasis iron ion transport plasma membrane ferric-chelate reductase (NADPH) activity ferric-chelate reductase activity metal ion binding Saccharomyces cerevisiae Cell membrane Copper Copper transport Electron transport FAD Flavoprotein Glycoprotein Heme Ion transport Iron I... |
actin cortical patch localization actin cytoskeleton organization actin filament bundle assembly endocytosis | actin cortical patch; cytosol | actin filament binding phosphatidylinositol binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Cytoskeleton Phosphoprotein Reference proteome SH3 domain | MGINNPIPRS | MGINNPIPRSLKSETKKAAKVLRSFVKPNQVFGADQVIPPYVLKRAKGLAIITVLKAGFLFSGRAGSGVIVARLKDGTWSAPSAIAMAGAGAGGMVGVELTDFVFILNSEEAVRSFSEFGTITLGGNVSVSAGPLGRSAEAAASASTGGVSAVFAYSKSKGLFAGVSVEGSAILERREANRKFYGDNCTSKMILSGRVKVPPAADPLLRILESRAFNFTRHDHDDNASGDDFYDDGQYSDNTSHYYDDIPDSFDSTDESSTRPNTRSSRRRGMSLGSRSRYDDDYDDDGYGRGRGYGDFDSEDEDYDYGRSPNRNSSRNR... | actin cortical patch localization actin cytoskeleton organization actin filament bundle assembly endocytosis actin cortical patch; cytosol actin filament binding phosphatidylinositol binding Saccharomyces cerevisiae 3D-structure Cytoplasm Cytoskeleton Phosphoprotein Reference proteome SH3 domain MGINNPIPRS MGINNPIPRSL... |
protein hexamerization response to xenobiotic stimulus ribosomal large subunit biogenesis | cytoplasm; preribosome, large subunit precursor | ATP binding ATP hydrolysis activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Chaperone Cytoplasm Hydrolase Nucleotide-binding Reference proteome Repeat Ribosome biogenesis | MAPKSSSSGS | MAPKSSSSGSKKKSSASSNSADAKASKFKLPAEFITRPHPSKDHGKETCTAYIHPNVLSSLEINPGSFCTVGKIGENGILVIARAGDEEVHPVNVITLSTTIRSVGNLILGDRLELKKAQVQPPYATKVTVGSLQGYNILECMEEKVIQKLLDDSGVIMPGMIFQNLKTKAGDESIDVVITDASDDSLPDVSQLDLNMDDMYGGLDNLFYLSPPFIFRKGSTHITFSKETQANRKYNLPEPLSYAAVGGLDKEIESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVANTSNAHVLTINGPSIVSKYL... | protein hexamerization response to xenobiotic stimulus ribosomal large subunit biogenesis cytoplasm; preribosome, large subunit precursor ATP binding ATP hydrolysis activity Saccharomyces cerevisiae 3D-structure ATP-binding Chaperone Cytoplasm Hydrolase Nucleotide-binding Reference proteome Repeat Ribosome biogenesis ... |
mitochondrion organization protein catabolic process protein folding protein import into mitochondrial intermembrane space protein import into mitochondrial matrix protein maturation protein quality control for misfolded or incompletely synthesized proteins | i-AAA complex; mitochondrial inner membrane; mitochondrion | ATP binding ATP hydrolysis activity ATP-dependent peptidase activity metal ion binding metalloendopeptidase activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Hydrolase Membrane Metal-binding Metalloprotease Mitochondrion Mitochondrion inner membrane Nucleotide-binding Protease Reference proteome Zinc | MNVSKILVSP | MNVSKILVSPTVTTNVLRIFAPRLPQIGASLLVQKKWALRSKKFYRFYSEKNSGEMPPKKEADSSGKASNKSTISSIDNSQPPPPSNTNDKTKQANVAVSHAMLATREQEANKDLTSPDAQAAFYKLLLQSNYPQYVVSRFETPGIASSPECMELYMEALQRIGRHSEADAVRQNLLTASSAGAVNPSLASSSSNQSGYHGNFPSMYSPLYGSRKEPLHVVVSESTFTVVSRWVKWLLVFGILTYSFSEGFKYITENTTLLKSSEVADKSVDVAKTNVKFDDVCGCDEARAELEEIVDFLKDPTKYESLGGKLPKGVLLT... | mitochondrion organization protein catabolic process protein folding protein import into mitochondrial intermembrane space protein import into mitochondrial matrix protein maturation protein quality control for misfolded or incompletely synthesized proteins i-AAA complex; mitochondrial inner membrane; mitochondrion ATP... |
carnitine metabolic process fatty acid metabolic process | mitochondrial inner membrane; mitochondrion; peroxisome | carnitine O-acetyltransferase activity | Saccharomyces cerevisiae | Acyltransferase Alternative initiation Fatty acid metabolism Lipid metabolism Membrane Mitochondrion Mitochondrion inner membrane Peroxisome Reference proteome Transferase Transit peptide Transport | MRICHSRTLS | MRICHSRTLSNLKDLPITSRRAMHSAIVNYSTQKAQFPVETNNGEHYWAEKPNKFYQNKRPNFQGITFAKQQDLPSLPVPELKSTLDKYLQTIRPFCNDVETFERQQLLCKDFSEHMGPILQDRLKEYANDKRNWMAKFWDEQSYLQYNDPIVPYVSYFYSHMPLPNHLSKIDNDPLIKATAIISTVVKFIEAIKDESLPVEIIKGMPFCMNSFSLMFNTSRLPGKPEDNQDTNIFYSVYENNFVTIAYKGKFYKLMTHDGNDKPLSENEIWRQLYSVVFQGSQSDPKLGGIGSLTSLPRDQWREVHLELMKDPISQDSL... | carnitine metabolic process fatty acid metabolic process mitochondrial inner membrane; mitochondrion; peroxisome carnitine O-acetyltransferase activity Saccharomyces cerevisiae Acyltransferase Alternative initiation Fatty acid metabolism Lipid metabolism Membrane Mitochondrion Mitochondrion inner membrane Peroxisome R... |
cell cycle cell division regulation of telomere maintenance via telomerase ribonucleoprotein complex localization telomere capping telomere maintenance telomere maintenance via telomerase | chromosome, telomeric region; CST complex; nuclear telomere cap complex | G-rich strand telomeric DNA binding identical protein binding single-stranded telomeric DNA binding telomerase inhibitor activity translation elongation factor binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Cell division Chromosome DNA-binding Phosphoprotein Reference proteome Telomere | MDTLEEPECP | MDTLEEPECPPHKNRIFVSSSKDFEGYPSKAIVPVQFVALLTSIHLTETKCLLGFSNFERRGDQSQEDQYLIKLKFKDRGSERLARITISLLCQYFDIELPDLDSDSGASPTVILRDIHLERLCFSSCKALYVSKHGNYTLFLEDIKPLDLVSVISTISTKSTNSSKHSSSELISECDLNNSLVDIFNNLIEMNRDEKNRFKFVKLIHYDIELKKFVQDQQKVLSQKSKAAAINPFFVPNRLGIPYIESQNEFNSQLMTLNVDEPTTDISNMGEEMHDSADPIEDSDSSTTSSTGKYFSSKSYIQSQTPERKTSVPNNWH... | cell cycle cell division regulation of telomere maintenance via telomerase ribonucleoprotein complex localization telomere capping telomere maintenance telomere maintenance via telomerase chromosome, telomeric region; CST complex; nuclear telomere cap complex G-rich strand telomeric DNA binding identical protein bindin... |
cobalt ion transport intracellular zinc ion homeostasis zinc ion transmembrane transport zinc ion transport | fungal-type vacuole; fungal-type vacuole membrane; mitochondrion | cobalt ion transmembrane transporter activity zinc ion transmembrane transporter activity | Saccharomyces cerevisiae | Cobalt Isopeptide bond Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport Ubl conjugation Vacuole Zinc | MKLGSKQVKI | MKLGSKQVKIISLLLLDTVFFGIEITTGYLSHSLALIADSFHMLNDIISLVVALWAVNVAKNRNPDSTYTYGWKRAEILGALINAVFLIALCVSILIEALQRIIAPPVIENPKFVLYVGVAGLISNTVGLFLFHDNDQEHGHGHGHSHGGIFADHEMHMPSSHTHTHAHVDGIENTTPMDSTDNISEIMPNAIVDSFMNENTRLLTPENASKTPSYSTSSHTIASGGNYTEHNKRKRSLNMHGVFLHVLGDALGNIGVMLSAFFIWKTDYSWKYYTDPLVSLIITGIIFSSALPLSCKASKILLQATPSTLSGDQVEGDL... | cobalt ion transport intracellular zinc ion homeostasis zinc ion transmembrane transport zinc ion transport fungal-type vacuole; fungal-type vacuole membrane; mitochondrion cobalt ion transmembrane transporter activity zinc ion transmembrane transporter activity Saccharomyces cerevisiae Cobalt Isopeptide bond Membrane... |
aerobic respiration mitochondrial electron transport, cytochrome c to oxygen mitochondrial respirasome assembly proton transmembrane transport | mitochondrial respiratory chain complex IV; mitochondrion | enzyme regulator activity oxidoreductase activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Membrane Mitochondrion Mitochondrion inner membrane Oxidoreductase Reference proteome Transit peptide Transmembrane Transmembrane helix | MFRQCAKRYA | MFRQCAKRYASSLPPNALKPAFGPPDKVAAQKFKESLMATEKHAKDTSNMWVKISVWVALPAIALTAVNTYFVEKEHAEHREHLKHVPDSEWPRDYEFMNIRSKPFFWGDGDKTLFWNPVVNRHIEHDD | aerobic respiration mitochondrial electron transport, cytochrome c to oxygen mitochondrial respirasome assembly proton transmembrane transport mitochondrial respiratory chain complex IV; mitochondrion enzyme regulator activity oxidoreductase activity Saccharomyces cerevisiae 3D-structure Direct protein sequencing Memb... |
protein import into peroxisome matrix protein import into peroxisome matrix, receptor recycling protein import into peroxisome matrix, substrate release protein monoubiquitination protein polyubiquitination protein ubiquitination | peroxisomal importomer complex; peroxisomal membrane; ubiquitin ligase complex | protein transmembrane transporter activity ubiquitin protein ligase activity zinc ion binding | Saccharomyces cerevisiae | Alternative initiation Membrane Metal-binding Peroxisome Protein transport Reference proteome Transferase Transmembrane Transmembrane helix Transport Ubl conjugation pathway Zinc Zinc-finger | MSRVAQLDSI | MSRVAQLDSIALDKELYGQFWSEFNAAFNTSEHKEEWELALNTVVFMCATRFLPHYGSSCTYGSALSGVVFQCRKRTLYVVTVLAGYVWKKITHIIFNGPHCGNQMMWLKLYKWVNLLYHGCDVTNFLRFLAAEGPNARAFLSPLYRAFNVHSTRLIRDGSAIASEFYSNSVFAGLEYQNRQLLWNALLELFSNTLLTKRGLLTFVKKPPRSRSTTTYKTVCPRCGGFPTNPYQIACCRANYCYVCVVKALEWSMCDACGSSGRLTASPVY | protein import into peroxisome matrix protein import into peroxisome matrix, receptor recycling protein import into peroxisome matrix, substrate release protein monoubiquitination protein polyubiquitination protein ubiquitination peroxisomal importomer complex; peroxisomal membrane; ubiquitin ligase complex protein tra... |
budding cell bud growth cell morphogenesis cellular response to glucose starvation intracellular signal transduction mitotic cytokinesis phosphorylation protein localization to septin ring pseudohyphal growth septin ring assembly | cellular bud neck; cellular bud neck septin ring; cytoplasm | ATP binding metal ion binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | ATP-binding Cell cycle Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MSPRQLIPTL | MSPRQLIPTLIPEWAPLSQQSCIREDELDSPPITPTSQTSSFGSSFSQQKPTYSTIIGENIHTILDEIRPYVKKITVSDQDKKTINQYTLGVSAGSGQFGYVRKAYSSTLGKVVAVKIIPKKPWNAQQYSVNQVMRQIQLWKSKGKITTNMSGNEAMRLMNIEKCRWEIFAASRLRNNVHIVRLIECLDSPFSESIWIVTNWCSLGELQWKRDDDEDILPQWKKIVISNCSVSTFAKKILEDMTKGLEYLHSQGCIHRDIKPSNILLDEEEKVAKLSDFGSCIFTPQSLPFSDANFEDCFQRELNKIVGTPAFIAPELCH... | budding cell bud growth cell morphogenesis cellular response to glucose starvation intracellular signal transduction mitotic cytokinesis phosphorylation protein localization to septin ring pseudohyphal growth septin ring assembly cellular bud neck; cellular bud neck septin ring; cytoplasm ATP binding metal ion binding ... |
chromatin organization double-strand break repair via break-induced replication double-strand break repair via homologous recombination double-strand break repair via nonhomologous end joining establishment of protein-containing complex localization to telomere mitochondrial double-strand break repair via homologous re... | chromosome, telomeric region; Ku70:Ku80 complex; nuclear envelope | ATP binding ATP hydrolysis activity damaged DNA binding DNA helicase activity telomerase RNA binding telomeric DNA binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Chromosome Direct protein sequencing DNA damage DNA recombination DNA repair DNA-binding Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Telomere Ubl conjugation | MRSVTNAFGN | MRSVTNAFGNSGELNDQVDETGYRKFDIHEGILFCIELSETMFKESSDLEYKSPLLEILESLDELMSQLVITRPGTAIGCYFYYCNREDAKEGIYELFPLRDINATFMKKLNDLLEDLSSGRISLYDYFMFQQTGSEKQVRLSVLFTFMLDTFLEEIPGQKQLSNKRVFLFTDIDKPQEAQDIDERARLRRLTIDLFDNKVNFATFFIGYADKPFDNEFYSDILQLGSHTNENTGLDSEFDGPSTKPIDAKYIKSRILRKKEVKRIMFQCPLILDEKTNFIVGVKGYTMYTHEKAGVRYKLVYEHEDIRQEAYSKRKFLN... | chromatin organization double-strand break repair via break-induced replication double-strand break repair via homologous recombination double-strand break repair via nonhomologous end joining establishment of protein-containing complex localization to telomere mitochondrial double-strand break repair via homologous re... |
conjugation with cellular fusion negative regulation of conjugation with cellular fusion negative regulation of induction of conjugation with cellular fusion negative regulation of MAPK cascade proteolysis involved in protein catabolic process | cytosol; extracellular region; nucleus | carboxypeptidase activity serine-type carboxypeptidase activity | Schizosaccharomyces pombe | Carboxypeptidase Glycoprotein Hydrolase Protease Reference proteome Secreted Signal Zymogen | MLSLFLKSLF | MLSLFLKSLFAIIIIELTIIHALPTYTVHWKCSIQQANTSSASSNQTVQPRQHAAPSSDRIKSLPEFKGSLPELYSGYLEANSDKSLFYTYAPAVVDSETFIVWLQGGPGCAGTLGFFSENGPIEISQSSPSPSLNPESWTNFANMLWLDQPFGTGYSQGQAAYTTTIEEASSDFVNALKSFYQKFPHLMKKKLYLVGESYGSIWSANFAEALLSEPSLNINFMGVGIVSGLTADYETQEQITASIWVEHISKLGYYFNNTSSTISEEFKKRNKECQYDSVLNRLTFPTEQYPIWRPEYNFSTSTSLRKREALDGEDIGN... | conjugation with cellular fusion negative regulation of conjugation with cellular fusion negative regulation of induction of conjugation with cellular fusion negative regulation of MAPK cascade proteolysis involved in protein catabolic process cytosol; extracellular region; nucleus carboxypeptidase activity serine-type... |
apoptotic process DNA damage response DNA repair protein sumoylation protein ubiquitination telomere maintenance ubiquitin-dependent protein catabolic process | chromosome, centromeric region; kinetochore; nucleus; SUMO-targeted ubiquitin ligase complex | SUMO binding transferase activity | Saccharomyces cerevisiae | Centromere Chromosome DNA damage DNA repair Kinetochore Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Transferase Ubl conjugation pathway | MHSDTNGRTK | MHSDTNGRTKSNNSPSDNNPNETVILIDSDKEEDASIREANLPVRLYPDRRVGRRRDALNRFVRSDSRSRNSQRTHITASSERPDFQANNDDITIIREVGRFFGDDGPIDPSAHYVDLDQEPGSETLETPRTIQVDNTNGYLNDNGNNNESDDGLTIVEERTTRPRVTLNLPGGERLEVTATTTDIPIRRSFEFQEDLGASRRQLLRRSATRARNLFVDRSDENDEDWTDDTHNLPEAIQRARRESRMRMSRRIAERQRRVQQQRVSSDENISTSIRLQSIRERIQSYTPDIRSAFHRAESLHEFRSILQNVAPITLQEC... | apoptotic process DNA damage response DNA repair protein sumoylation protein ubiquitination telomere maintenance ubiquitin-dependent protein catabolic process chromosome, centromeric region; kinetochore; nucleus; SUMO-targeted ubiquitin ligase complex SUMO binding transferase activity Saccharomyces cerevisiae Centrome... |
ascospore formation base-excision repair DNA double-strand break processing involved in repair via synthesis-dependent strand annealing DNA repair double-strand break repair double-strand break repair via break-induced replication double-strand break repair via homologous recombination double-strand break repair via no... | mitochondrion; Mre11 complex; nucleoplasm; nucleus; site of double-strand break | 3'-5' exonuclease activity 3'-5'-DNA exonuclease activity DNA endonuclease activity double-stranded telomeric DNA binding endonuclease activity G-quadruplex DNA binding manganese ion binding molecular adaptor activity single-stranded DNA endodeoxyribonuclease activity single-stranded telomeric DNA binding telomeric DNA... | Saccharomyces cerevisiae | DNA damage DNA repair Endonuclease Exonuclease Hydrolase Manganese Meiosis Nuclease Nucleus Reference proteome | MDYPDPDTIR | MDYPDPDTIRILITTDNHVGYNENDPITGDDSWKTFHEVMMLAKNNNVDMVVQSGDLFHVNKPSKKSLYQVLKTLRLCCMGDKPCELELLSDPSQVFHYDEFTNVNYEDPNFNISIPVFGISGNHDDASGDSLLCPMDILHATGLINHFGKVIESDKIKVVPLLFQKGSTKLALYGLAAVRDERLFRTFKDGGVTFEVPTMREGEWFNLMCVHQNHTGHTNTAFLPEQFLPDFLDMVIWGHEHECIPNLVHNPIKNFDVLQPGSSVATSLCEAEAQPKYVFILDIKYGEAPKMTPIPLETIRTFKMKSISLQDVPHLRPH... | ascospore formation base-excision repair DNA double-strand break processing involved in repair via synthesis-dependent strand annealing DNA repair double-strand break repair double-strand break repair via break-induced replication double-strand break repair via homologous recombination double-strand break repair via no... |
protein insertion into mitochondrial inner membrane protein transmembrane transport | mitochondrial inner membrane; mitochondrial intermembrane space protein transporter complex; mitochondrion; TIM22 mitochondrial import inner membrane insertion complex | metal ion binding phospholipid binding | Saccharomyces cerevisiae | 3D-structure Acetylation Disulfide bond Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Protein transport Reference proteome Translocation Transport Zinc | MSFFLNSLRG | MSFFLNSLRGNQEVSQEKLDVAGVQFDAMCSTFNNILSTCLEKCIPHEGFGEPDLTKGEQCCIDRCVAKMHYSNRLIGGFVQTRGFGPENQLRHYSRFVAKEIADDSKK | protein insertion into mitochondrial inner membrane protein transmembrane transport mitochondrial inner membrane; mitochondrial intermembrane space protein transporter complex; mitochondrion; TIM22 mitochondrial import inner membrane insertion complex metal ion binding phospholipid binding Saccharomyces cerevisiae 3D-... |
chromatin remodeling nucleosome disassembly transcription elongation by RNA polymerase II | chromatin; nucleus; RSC-type complex | chromatin DNA binding | Saccharomyces cerevisiae | 3D-structure Chromatin regulator Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSDSEGGLAS | MSDSEGGLASEVEHEKRSRSTSNRPNYAIDTEDLDIDENDENEDDDYREEEANEGVNEEEISDEEEQINKSGRNKRRHVDEEEDLSEDKGVTRSRNRSKFKKPVFPGIDDAEENLNPLKVVNEEYVLPDDPEGETKITADGDLLGGREFLVRTFTLTEKGNRKFMLATEPARIVGFRDSYLFFQTHPNLYKFILNQTQKNDLIDRGVLPYSYRNRQIALVTARGVFKEFGAKIIRGGKHITDDYYASELRTKGNVIEGKLAGDPIDKSARALETMMYPASENGINPAKNQVEFFEHRPHGHMSNSNIIASGSKLSSTNWL... | chromatin remodeling nucleosome disassembly transcription elongation by RNA polymerase II chromatin; nucleus; RSC-type complex chromatin DNA binding Saccharomyces cerevisiae 3D-structure Chromatin regulator Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation MSDSEGGLAS MSDSEGGLASEVEHEKRSRS... |
DNA replication initiation pre-replicative complex assembly involved in nuclear cell cycle DNA replication silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation | chromosome, telomeric region; DNA replication preinitiation complex; nuclear origin of replication recognition complex; nuclear pre-replicative complex; nucleoplasm; nucleus | chromatin binding DNA replication origin binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing DNA replication Nucleus Phosphoprotein Reference proteome | MLNGEDFVEH | MLNGEDFVEHNDILSSPAKSRNVTPKRVDPHGERQLRRIHSSKKNLLERISLVGNERKNTSPDPALKPKTPSKAPRKRGRPRKIQEELTDRIKKDEKDTISSKKKRKLDKDTSGNVNEESKTSNNKQVMEKTGIKEKREREKIQVATTTYEDNVTPQTDDNFVSNSPEPPEPATPSKKSLTTNHDFTSPLKQIIMNNLKEYKDSTSPGKLTLSRNFTPTPVPKNKKLYQTSETKSASSFLDTFEGYFDQRKIVRTNAKSRHTMSMAPDVTREEFSLVSNFFNENFQKRPRQKLFEIQKKMFPQYWFELTQGFSLLFYGVG... | DNA replication initiation pre-replicative complex assembly involved in nuclear cell cycle DNA replication silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation chromosome, telomeric region; DNA replication preinitiation complex; nuclear origin of replication recognition complex; ... |
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus organization poly(A)+ mRNA export from nucleus protein import into nucleus regulation of cell cycle phase transition regulation of nucleocytoplasmic transport ribosomal subunit export... | cytoplasm; cytosol; nucleus | GTP binding GTPase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Direct protein sequencing GTP-binding Nucleotide-binding Nucleus Phosphoprotein Protein transport Reference proteome Transport | MSAPAANGEV | MSAPAANGEVPTFKLVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGYYINAQCAIIMFDVTSRITYKNVPNWHRDLVRVCENIPIVLCGNKVDVKERKVKAKTITFHRKKNLQYYDISAKSNYNFEKPFLWLARKLAGNPQLEFVASPALAPPEVQVDEQLMQQYQQEMEQATALPLPDEDDADL | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus organization poly(A)+ mRNA export from nucleus protein import into nucleus regulation of cell cycle phase transition regulation of nucleocytoplasmic transport ribosomal subunit export... |
asymmetric protein localization to old mitotic spindle pole body glycogen metabolic process | cytoplasm; FAR/SIN/STRIPAK complex; nucleus | metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity | Saccharomyces cerevisiae | Hydrolase Manganese Metal-binding Methylation Protein phosphatase Reference proteome | MELDECLERL | MELDECLERLYKAQLLPEVTVRALCFKLKEMLVKESNVIHIQTPVTVVGDMHGQFHDMLEIFQIGGPVPDTNYLFLGDYVDRGLYSVETIMLLIVLKLRYPSRIHLLRGNHESRQITQSYGFYTECLNKYGGNSRVWQYLTDIFDYLVLCCIIDDEIFCVHGGLSPNVQTIDQIKIIDRFREIPHDGAMADLVWSDPEENNNPTLDHPDNSGQHFQVSPRGAGYTFGRSVVEKFLRMNDMNRIYRAHQLCNEGYQIYFDGLVTTVWSAPNYCYRCGNKASILELYSKDQFYFNVFEEAPENKLLKENSMNDNALEDSISN... | asymmetric protein localization to old mitotic spindle pole body glycogen metabolic process cytoplasm; FAR/SIN/STRIPAK complex; nucleus metal ion binding myosin phosphatase activity protein serine/threonine phosphatase activity Saccharomyces cerevisiae Hydrolase Manganese Metal-binding Methylation Protein phosphatase ... |
chaperone-mediated protein complex assembly mitochondrial respiratory chain complex III assembly protein insertion into mitochondrial inner membrane from matrix | cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion | ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transporter activity protein transmembrane transporter activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Reference proteome Transmembrane Transmembrane helix | MSDKPIDIQY | MSDKPIDIQYDKQATPNLSGVITPPTNETGNDSVREKLSKLVGDAMSNNPYFAAGGGLMILGTGLAVARSGIIKASRVLYRQMIVDLEIQSKDKSYAWFLTWMAKHPQRVSRHLSVRTNYIQHDNGSVSTKFSLVPGPGNHWIRYKGAFILIKRERSAKMIDIANGSPFETVTLTTLYRDKHLFDDILNEAKDIALKTTEGKTVIYTSFGPEWRKFGQPKAKRMLPSVILDSGIKEGILDDVYDFMKNGKWYSDRGIPYRRGYLLYGPPGSGKTSFIQALAGELDYNICILNLSENNLTDDRLNHLMNNMPERSILLLED... | chaperone-mediated protein complex assembly mitochondrial respiratory chain complex III assembly protein insertion into mitochondrial inner membrane from matrix cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion ATP binding ATP hydrolysis activity ATPase-coupled transmembrane transp... |
endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification | cell periphery; fungal-type vacuole; fungal-type vacuole membrane; Golgi membrane; membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase, V0 domain | proton-transporting ATPase activity, rotational mechanism | Saccharomyces cerevisiae | 3D-structure Hydrogen ion transport Ion transport Membrane Reference proteome Transmembrane Transmembrane helix Transport Vacuole | MSTQLASNIY | MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE | endosomal lumen acidification Golgi lumen acidification proton transmembrane transport vacuolar acidification cell periphery; fungal-type vacuole; fungal-type vacuole membrane; Golgi membrane; membrane; proton-transporting V-type ATPase complex; vacuolar proton-transporting V-type ATPase complex; vacuolar proton-transp... |
exocyst localization exocytosis Golgi to plasma membrane transport negative regulation of SNARE complex assembly protein transport vesicle docking involved in exocytosis | cellular bud neck; cellular bud tip; exocyst; mating projection tip; prospore membrane | SNARE binding | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Exocytosis Protein transport Reference proteome Transport | MSSDPLQQVC | MSSDPLQQVCDLIKGDLSLERVRDIKEQLLKEKSVVEYQLNKESDKYYGEVEESLKLLNLSKNSVTSIKQQINEVNKLGNDNRFAINRYDILFRATKLYETVNTTSSIYDRIYNFVALMEHIERLLVAELAEDALETGCPHLLEIHFLLTSARDFQEQVVVMAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKKEIEIEKSSIKKLPNSKNTARLQDETPKVIEYPTNKGLYQEIMSGTISTRTAPRGYKHFLINGINNSISEMFGEMREKYVGDQ... | exocyst localization exocytosis Golgi to plasma membrane transport negative regulation of SNARE complex assembly protein transport vesicle docking involved in exocytosis cellular bud neck; cellular bud tip; exocyst; mating projection tip; prospore membrane SNARE binding Saccharomyces cerevisiae 3D-structure Acetylatio... |
excitatory chemical synaptic transmission gene expression inhibitory chemical synaptic transmission | axon; cuticular plate; cytoplasm; cytosol; neuronal cell body; protein-containing complex; stereocilium; synapse | calcium ion binding identical protein binding protein-containing complex binding | Mus musculus | Acetylation Calcium Direct protein sequencing Metal-binding Muscle protein Phosphoprotein Reference proteome Repeat | MSMTDVLSAE | MSMTDVLSAEDIKKAIGAFAAADSFDHKKFFQMVGLKKKNPDEVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLLAAGDKDGDGKIGVEEFSTLVAES | excitatory chemical synaptic transmission gene expression inhibitory chemical synaptic transmission axon; cuticular plate; cytoplasm; cytosol; neuronal cell body; protein-containing complex; stereocilium; synapse calcium ion binding identical protein binding protein-containing complex binding Mus musculus Acetylation C... |
calcium-ion regulated exocytosis exocytosis insulin secretion intracellular protein transport positive regulation of calcium ion-dependent exocytosis positive regulation of catecholamine secretion positive regulation of excitatory postsynaptic potential positive regulation of neurotransmitter secretion positive regulat... | axon; endomembrane system; nuclear membrane; plasma membrane; presynaptic active zone membrane; SNARE complex; synaptic vesicle; synaptic vesicle membrane; synaptobrevin 2-SNAP-25-syntaxin-1a complex | calcium channel inhibitor activity chloride channel inhibitor activity identical protein binding kinase binding SNAP receptor activity SNARE binding | Bos taurus | Cell membrane Coiled coil Cytoplasmic vesicle Direct protein sequencing Exocytosis Isopeptide bond Membrane Neurotransmitter transport Phosphoprotein Reference proteome Synapse Synaptosome Transmembrane Transmembrane helix Transport Ubl conjugation | MKDRTQELRT | MKDRTQELRTAKDSDDDDDVTVTVDRDRFMDEFFEQVEEIRGFIDKISENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIVICCVVLGIVIASTFGGIFG | calcium-ion regulated exocytosis exocytosis insulin secretion intracellular protein transport positive regulation of calcium ion-dependent exocytosis positive regulation of catecholamine secretion positive regulation of excitatory postsynaptic potential positive regulation of neurotransmitter secretion positive regulat... |
calcium-ion regulated exocytosis exocytosis hormone secretion insulin secretion intracellular protein transport modulation of excitatory postsynaptic potential neurotransmitter transport positive regulation of calcium ion-dependent exocytosis positive regulation of catecholamine secretion positive regulation of excitat... | acrosomal vesicle; actomyosin; axon; endomembrane system; glutamatergic synapse; membrane; neuron projection; nuclear membrane; plasma membrane; postsynaptic density; postsynaptic density membrane; presynapse; presynaptic active zone membrane; presynaptic membrane; protein-containing complex; Schaffer collateral - CA1 ... | ATP-dependent protein binding calcium channel inhibitor activity calcium-dependent protein binding chloride channel inhibitor activity identical protein binding kinase binding myosin binding myosin head/neck binding protein-containing complex binding protein-macromolecule adaptor activity SNAP receptor activity SNARE b... | Rattus norvegicus | 3D-structure Cell membrane Coiled coil Cytoplasmic vesicle Direct protein sequencing Exocytosis Isopeptide bond Membrane Neurotransmitter transport Phosphoprotein Reference proteome Synapse Synaptosome Transmembrane Transmembrane helix Transport Ubl conjugation | MKDRTQELRT | MKDRTQELRTAKDSDDDDDVTVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIIIASTIGGIFG | calcium-ion regulated exocytosis exocytosis hormone secretion insulin secretion intracellular protein transport modulation of excitatory postsynaptic potential neurotransmitter transport positive regulation of calcium ion-dependent exocytosis positive regulation of catecholamine secretion positive regulation of excitat... |
cytoplasm to vacuole transport by the Cvt pathway Golgi to endosome transport Golgi to vacuole transport Golgi vesicle fusion to target membrane intracellular protein transport macroautophagy vacuole inheritance vesicle docking vesicle fusion | cytosol; endomembrane system; endosome; endosome membrane; fungal-type vacuole membrane; Golgi apparatus; Golgi membrane; SNARE complex | SNAP receptor activity SNARE binding | Saccharomyces cerevisiae | Coiled coil Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Ubl conjugation | MSEDEFFGGD | MSEDEFFGGDNEAVWNGSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINKRSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKESLEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQKRTSRWRVYLLIVLLVMLLFIFLIMKL | cytoplasm to vacuole transport by the Cvt pathway Golgi to endosome transport Golgi to vacuole transport Golgi vesicle fusion to target membrane intracellular protein transport macroautophagy vacuole inheritance vesicle docking vesicle fusion cytosol; endomembrane system; endosome; endosome membrane; fungal-type vacuol... |
acrosome reaction animal organ morphogenesis cellular response to oxidative stress cornified envelope assembly ectoderm development exocytosis intracellular protein transport signal transduction synaptic vesicle fusion to presynaptic active zone membrane vesicle docking | basolateral plasma membrane; endomembrane system; extracellular space; intracellular membrane-bounded organelle; lamellipodium; plasma membrane; presynaptic active zone membrane; protein-containing complex; SNARE complex; synaptic vesicle | calcium-dependent protein binding identical protein binding SNAP receptor activity SNARE binding structural molecule activity | Homo sapiens | Alternative splicing Coiled coil Membrane Reference proteome Transmembrane Transmembrane helix | MRDRLPDLTA | MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK | acrosome reaction animal organ morphogenesis cellular response to oxidative stress cornified envelope assembly ectoderm development exocytosis intracellular protein transport signal transduction synaptic vesicle fusion to presynaptic active zone membrane vesicle docking basolateral plasma membrane; endomembrane system;... |
iron-sulfur cluster assembly protein maturation by cluster transfer protein maturation by iron-sulfur cluster transfer | mitochondrial matrix; mitochondrion | 4 iron, 4 sulfur cluster binding iron ion binding | Saccharomyces cerevisiae | 3D-structure Mitochondrion Reference proteome Transit peptide | MFKSVAKLGK | MFKSVAKLGKSPIFYLNSQRLIHIKTLTTPNENALKFLSTDGEMLQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTINKDRMVHWNSIKPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEELIDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYVDEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK | iron-sulfur cluster assembly protein maturation by cluster transfer protein maturation by iron-sulfur cluster transfer mitochondrial matrix; mitochondrion 4 iron, 4 sulfur cluster binding iron ion binding Saccharomyces cerevisiae 3D-structure Mitochondrion Reference proteome Transit peptide MFKSVAKLGK MFKSVAKLGKSPIFY... |
(1->6)-beta-D-glucan biosynthetic process glycogen biosynthetic process glycogen metabolic process trehalose biosynthetic process UDP-glucose metabolic process | cytoplasm; cytoplasmic stress granule; plasma membrane | metal ion binding uridylyltransferase activity UTP:glucose-1-phosphate uridylyltransferase activity | Saccharomyces cerevisiae | 3D-structure Acetylation Magnesium Metal-binding Methylation Nucleotidyltransferase Phosphoprotein Reference proteome Transferase | MSTKKHTKTH | MSTKKHTKTHSTYAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNN... | (1->6)-beta-D-glucan biosynthetic process glycogen biosynthetic process glycogen metabolic process trehalose biosynthetic process UDP-glucose metabolic process cytoplasm; cytoplasmic stress granule; plasma membrane metal ion binding uridylyltransferase activity UTP:glucose-1-phosphate uridylyltransferase activity Sacch... |
chromatin remodeling DNA geometric change double-strand break repair via synthesis-dependent strand annealing heteroduplex formation reciprocal meiotic recombination telomere maintenance via recombination | cytoplasm; nucleus | ATP binding ATP hydrolysis activity ATP-dependent chromatin remodeler activity DNA binding DNA translocase activity helicase activity metal ion binding | Saccharomyces cerevisiae | ATP-binding DNA damage DNA repair DNA-binding Helicase Hydrolase Metal-binding Nucleotide-binding Nucleus Phosphoprotein Reference proteome Zinc | MARRRLPDRP | MARRRLPDRPPNGIGAGERPRLVPRPINVQDSVNRLTKPFRVPYKNTHIPPAAGRIATGSDNIVGGRSLRKRSATVCYSGLDINADEAEYNSQDISFSQLTKRRKDALSAQRLAKDPTRLSHIQYTLRRSFTVPIKGYVQRHSLPLTLGMKKKITPEPRPLHDPTDEFAIVLYDPSVDGEMIVHDTSMDNKEEESKKMIKSTQEKDNINKEKNSQEERPTQRIGRHPALMTNGVRNKPLRELLGDSENSAENKKKFASVPVVIDPKLAKILRPHQVEGVRFLYRCVTGLVMKDYLEAEAFNTSSEDPLKSDEKALTESQK... | chromatin remodeling DNA geometric change double-strand break repair via synthesis-dependent strand annealing heteroduplex formation reciprocal meiotic recombination telomere maintenance via recombination cytoplasm; nucleus ATP binding ATP hydrolysis activity ATP-dependent chromatin remodeler activity DNA binding DNA t... |
endoplasmic reticulum to Golgi vesicle-mediated transport protein geranylgeranylation protein targeting to membrane small GTPase mediated signal transduction vesicle-mediated transport | cytoplasm; cytosol; membrane; nucleus; Rab-protein geranylgeranyltransferase complex | GDP-dissociation inhibitor activity GTPase activator activity small GTPase binding | Saccharomyces cerevisiae | GTPase activation Phosphoprotein Reference proteome | MLSPERRPSM | MLSPERRPSMAERRPSFFSFTQNPSPLVVPHLAGIEDPLPATTPDKVDVLIAGTGMVESVLAAALAWQGSNVLHIDKNDYYGDTSATLTVDQIKRWVNEVNEGSVSCYKNAKLYVSTLIGSGKYSSRDFGIDLSPKILFAKSDLLSILIKSRVHQYLEFQSLSNFHTYENDCFEKLTNTKQEIFTDQNLPLMTKRNLMKFIKFVLNWEAQTEIWQPYAERTMSDFLGEKFKLEKPQVFELIFSIGLCYDLNVKVPEALQRIRRYLTSFDVYGPFPALCSKYGGPGELSQGFCRSAAVGGATYKLNEKLVSFNPTTKVATF... | endoplasmic reticulum to Golgi vesicle-mediated transport protein geranylgeranylation protein targeting to membrane small GTPase mediated signal transduction vesicle-mediated transport cytoplasm; cytosol; membrane; nucleus; Rab-protein geranylgeranyltransferase complex GDP-dissociation inhibitor activity GTPase activat... |
G protein-coupled receptor signaling pathway metarhodopsin inactivation phototransduction, visible light positive regulation of smoothened signaling pathway protein phosphorylation regulation of signal transduction | cytoplasm; plasma membrane | ATP binding G protein-coupled receptor binding G protein-coupled receptor kinase activity phosphatidylinositol binding rhodopsin kinase activity | Drosophila melanogaster | ATP-binding Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MADLEAVLAD | MADLEAVLADVSYLMAMEKSKCTPAARASKKLNLPDPSVRSVMYKYLEKEGELNFHKIFNEVLGYLLFKDFCENDSEEPIQQLKFFEQIKLFEKTECYDERKKMARDIYDNFIMEEMLSHTYEYSKHAVASVQKYLLKNEVPVDLFEPYLEEIFTQLKGKPFKKFLESDKFTRFCQWKNLELNIQLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGEMLALNERNMLQAVSTGIDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGIFSEDEMKFYAAEVILGLEHMHKRCIVYRDLK... | G protein-coupled receptor signaling pathway metarhodopsin inactivation phototransduction, visible light positive regulation of smoothened signaling pathway protein phosphorylation regulation of signal transduction cytoplasm; plasma membrane ATP binding G protein-coupled receptor binding G protein-coupled receptor kina... |
apical constriction involved in gastrulation defense response to Gram-positive bacterium imaginal disc-derived wing morphogenesis negative regulation of smoothened signaling pathway oocyte morphogenesis positive regulation of antibacterial peptide biosynthetic process positive regulation of protein kinase A signaling p... | cytoplasm; cytoplasmic side of plasma membrane; plasma membrane | ATP binding G protein-coupled receptor kinase activity phosphatidylinositol-4-phosphate binding protein kinase activity protein serine/threonine kinase activity | Drosophila melanogaster | ATP-binding Developmental protein Differentiation Kinase Membrane Nucleotide-binding Oogenesis Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase | MELENIVANT | MELENIVANTVYLKAREGGSDSNKGKSKKWRKILQFPHISQCINLKDKLDISYGYVIDQQPIGRELFRLFCENKRPVYFRYITFLDEVVKYEIEYISNRIFIGHDIGRRFLDVEAQLELRNGSGGDALDAETQEELLLNSSNANPTETAETEHCNNTTANNCNNINNSNNSQHSSDINHKKLDTRNHNGDDATGNGSSHQDDGDESVKCQEGHDDAEKGGGGEGGGGGKCVPVGGYPDELVLDVLNDDLIAQVRNKLNSGGKDIFAQCVNAVKAFLAGEPFREFESSMYFHRYLQWKWLEAQPITYKTFRMYRVLGKGGF... | apical constriction involved in gastrulation defense response to Gram-positive bacterium imaginal disc-derived wing morphogenesis negative regulation of smoothened signaling pathway oocyte morphogenesis positive regulation of antibacterial peptide biosynthetic process positive regulation of protein kinase A signaling p... |
ascospore formation ascospore-type prospore assembly exocytosis Golgi to plasma membrane transport Golgi vesicle fusion to target membrane intracellular protein transport SNARE complex assembly sporulation vesicle docking vesicle fusion vesicle fusion to plasma membrane | cell periphery; endomembrane system; fungal-type vacuole membrane; Golgi membrane; plasma membrane; prospore membrane; SNARE complex | phosphatidic acid binding phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-4,5-bisphosphate binding SNAP receptor activity SNARE binding | Saccharomyces cerevisiae | 3D-structure Coiled coil Membrane Reference proteome Transmembrane Transmembrane helix | MSYNNPYQLE | MSYNNPYQLETPFEESYELDEGSSAIGAEGHDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVNEEQASHLRHSLDNFVAQATDLQFKLKNEIKSAQRDGIHDTNKQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR | ascospore formation ascospore-type prospore assembly exocytosis Golgi to plasma membrane transport Golgi vesicle fusion to target membrane intracellular protein transport SNARE complex assembly sporulation vesicle docking vesicle fusion vesicle fusion to plasma membrane cell periphery; endomembrane system; fungal-type ... |
proton motive force-driven ATP synthesis | mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) | lipid binding proton transmembrane transporter activity | Bos taurus | 3D-structure CF(0) Direct protein sequencing Hydrogen ion transport Ion transport Lipid-binding Membrane Methylation Mitochondrion Reference proteome Transit peptide Transmembrane Transmembrane helix Transport | MQTTGALLIS | MQTTGALLISPALIRSCTRGLIRPVSASFLSRPEIQSVQPSYSSGPLQVARREFQTSVVSRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM | proton motive force-driven ATP synthesis mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) lipid binding proton transmembrane transporter activity Bos taurus 3D-structure CF(0) Direct protein sequencing Hydrogen ion transport Ion transpo... |
adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein response... | extracellular region; extracellular space | cytokine activity cytokine receptor binding type I interferon receptor binding | Homo sapiens | 3D-structure Antiviral defense Cytokine Direct protein sequencing Disulfide bond Reference proteome Secreted Signal | MALTFYLLVA | MALTFYLLVALVVLSYKSFSSLGCDLPQTHSLGNRRALILLAQMRRISPFSCLKDRHDFEFPQEEFDDKQFQKAQAISVLHEMIQQTFNLFSTKDSSAALDETLLDEFYIELDQQLNDLESCVMQEVGVIESPLMYEDSILAVRKYFQRITLYLTEKKYSSCAWEVVRAEIMRSFSLSINLQKRLKSKE | adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein response... |
microtubule cytoskeleton organization mitotic cell cycle negative regulation of microtubule polymerization | cytoplasm; microtubule | calcium ion binding GTP binding GTPase activity structural constituent of cytoskeleton | Gallus gallus | 3D-structure Cytoplasm Cytoskeleton GTP-binding Isopeptide bond Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREIVHIQAG | MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGR... | microtubule cytoskeleton organization mitotic cell cycle negative regulation of microtubule polymerization cytoplasm; microtubule calcium ion binding GTP binding GTPase activity structural constituent of cytoskeleton Gallus gallus 3D-structure Cytoplasm Cytoskeleton GTP-binding Isopeptide bond Magnesium Metal-binding M... |
actin cytoskeleton organization cell population proliferation cytokine-mediated signaling pathway epithelial tube branching involved in lung morphogenesis forebrain astrocyte development gene expression glial cell proliferation homeostasis of number of cells within a tissue insulin-like growth factor receptor signaling... | cytoplasm; cytoplasmic side of plasma membrane; endomembrane system; membrane; plasma membrane | G protein activity GDP binding GMP binding GTP binding GTPase activity identical protein binding LRR domain binding protein-containing complex binding protein-membrane adaptor activity | Mus musculus | Acetylation Alternative splicing Cell membrane Cytoplasm GTP-binding Hydrolase Isopeptide bond Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Prenylation Proto-oncogene Reference proteome Ubl conjugation | MTEYKLVVVG | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQELARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGCVKIKKCVIM | actin cytoskeleton organization cell population proliferation cytokine-mediated signaling pathway epithelial tube branching involved in lung morphogenesis forebrain astrocyte development gene expression glial cell proliferation homeostasis of number of cells within a tissue insulin-like growth factor receptor signaling... |
lactate catabolic process | mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion | D-lactate dehydrogenase (cytochrome) activity D-lactate dehydrogenase activity FAD binding flavin adenine dinucleotide binding | Saccharomyces cerevisiae | Direct protein sequencing FAD Flavoprotein Membrane Mitochondrion Mitochondrion inner membrane Oxidoreductase Reference proteome Transit peptide | MLWKRTCTRL | MLWKRTCTRLIKPIAQPRGRLVRRSCYRYASTGTGSTDSSSQWLKYSVIASSATLFGYLFAKNLYSRETKEDLIEKLEMVKKIDPVNSTLKLSSLDSPDYLHDPVKIDKVVEDLKQVLGNKPENYSDAKSDLDAHSDTYFNTHHPSPEQRPRIILFPHTTEEVSKILKICHDNNMPVVPFSGGTSLEGHFLPTRIGDTITVDLSKFMNNVVKFDKLDLDITVQAGLPWEDLNDYLSDHGLMFGCDPGPGAQIGGCIANSCSGTNAYRYGTMKENIINMTIVLPDGTIVKTKKRPRKSSAGYNLNGLFVGSEGTLGIVTEA... | lactate catabolic process mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion D-lactate dehydrogenase (cytochrome) activity D-lactate dehydrogenase activity FAD binding flavin adenine dinucleotide binding Saccharomyces cerevisiae Direct protein sequencing FAD Flavoprotein Membrane Mitochondr... |
ribosomal large subunit assembly rRNA processing | nucleolus; preribosome, large subunit precursor | ATP binding ATP hydrolysis activity RNA binding RNA helicase activity | Saccharomyces cerevisiae | ATP-binding Coiled coil Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ribosome biogenesis RNA-binding | MVVGTKKYSN | MVVGTKKYSNLDFVPTISDSEDDVPILDSSDDEKVEAKKTTKKRKGKNNKKKVSEGDNLDEDVHEDLDAGFKFDLDADDTTSNFQGWNFLAEGESNKDDAEAFVKKDVDLDKIIRRKGGLVKMAHIDSKQEEETEKEKVEKENDSDDEELAMDGFGMGAPMNNGDENQSEEEEEEEEKEEEEEEEEEQEEMTLEKGGKDDEIDEEDDSEEAKADFYAPETEGDEAKKQMYENFNSLSLSRPVLKGLASLGYVKPSPIQSATIPIALLGKDIIAGAVTGSGKTAAFMIPIIERLLYKPAKIASTRVIVLLPTRELAIQVAD... | ribosomal large subunit assembly rRNA processing nucleolus; preribosome, large subunit precursor ATP binding ATP hydrolysis activity RNA binding RNA helicase activity Saccharomyces cerevisiae ATP-binding Coiled coil Helicase Hydrolase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Ribosome biogenesis RNA... |
5-phosphoribose 1-diphosphate biosynthetic process fungal-type cell wall organization phosphorylation purine nucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process | cytoplasm; cytoplasmic stress granule; ribose phosphate diphosphokinase complex | ATP binding kinase activity magnesium ion binding ribose phosphate diphosphokinase activity | Saccharomyces cerevisiae | ATP-binding Cytoplasm Kinase Magnesium Metal-binding Nucleotide biosynthesis Nucleotide-binding Phosphoprotein Reference proteome Transferase | MRKCKIFVGN | MRKCKIFVGNSHPELGNMVCQRLGIEPAPCTLKKFANGETSVQIGVSVRDEDVYVIQSGSPSINDDIMELLILVSACRGGSARKITAVIPQFPYSKQCKMKRHRGAITARMLANLLVMAGADHVVSMDLHASQMQGFFTKPVDNLYGGPSLAKWIRENVEDYEDAVVVSKNPGGTKRVTALADSLKINFAMIHTDRRRSKDLYSQNKDLQQLKLRKQSMLRKNRPIIRQGDHPNEEENIILSNGIQTARIRNGHVIGDDEADDDEDAILESDSELHSIDGLDSHGLGGTYDAVDSEDEEEIPVLYREQLITLVGNVRGRS... | 5-phosphoribose 1-diphosphate biosynthetic process fungal-type cell wall organization phosphorylation purine nucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process cytoplasm; cytoplasmic stress granule; ribose phosphate diphosphokinase complex ATP binding kinase activity magnesium ion binding... |
intracellular protein transport protein import into mitochondrial matrix protein insertion into mitochondrial inner membrane | mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; TIM23 mitochondrial import inner membrane translocase complex | mitochondrion targeting sequence binding protein transmembrane transporter activity | Saccharomyces cerevisiae | 3D-structure Membrane Mitochondrion Mitochondrion inner membrane Protein transport Reference proteome Translocation Transmembrane Transmembrane helix Transport | MSWLFGDKTP | MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK | intracellular protein transport protein import into mitochondrial matrix protein insertion into mitochondrial inner membrane mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; TIM23 mitochondrial import inner membrane translocase complex mitochondrion targeting sequence binding protein tran... |
protein processing proteolysis involved in protein catabolic process | mitochondrial intermembrane space; mitochondrial matrix; mitochondrion | ATP-dependent peptidase activity metalloendopeptidase activity zinc ion binding | Saccharomyces cerevisiae | Direct protein sequencing Hydrolase Metal-binding Metalloprotease Mitochondrion Phosphoprotein Protease Reference proteome Transit peptide Zinc | MLRFQRFASS | MLRFQRFASSYAQAQAVRKYPVGGIFHGYEVRRILPVPELRLTAVDLVHSQTGAEHLHIDRDDKNNVFSIAFKTNPPDSTGVPHILEHTTLCGSVKYPVRDPFFKMLNKSLANFMNAMTGPDYTFFPFSTTNPQDFANLRGVYLDSTLNPLLKQEDFDQEGWRLEHKNITDPESNIVFKGVVYNEMKGQISNANYYFWSKFQQSIYPSLNNSGGDPMKITDLRYGDLLDFHHKNYHPSNAKTFTYGNLPLVDTLKQLNEQFSGYGKRARKDKLLMPIDLKKDIDVKLLGQIDTMLPPEKQTKASMTWICGAPQDTYDTFL... | protein processing proteolysis involved in protein catabolic process mitochondrial intermembrane space; mitochondrial matrix; mitochondrion ATP-dependent peptidase activity metalloendopeptidase activity zinc ion binding Saccharomyces cerevisiae Direct protein sequencing Hydrolase Metal-binding Metalloprotease Mitochon... |
maturation of SSU-rRNA ribosomal small subunit biogenesis rRNA processing | 90S preribosome; Mpp10 complex; nucleolus; nucleoplasm; small ribosomal subunit; small-subunit processome | rRNA binding snoRNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Nucleus Reference proteome Ribonucleoprotein Ribosome biogenesis RNA-binding rRNA processing rRNA-binding | MVRKLKHHEQ | MVRKLKHHEQKLLKKVDFLEWKQDQGHRDTQVMRTYHIQNREDYHKYNRICGDIRRLANKLSLLPPTDPFRRKHEQLLLDKLYAMGVLTTKSKISDLENKVTVSAICRRRLPVIMHRLKMAETIQDAVKFIEQGHVRVGPNLINDPAYLVTRNMEDYVTWVDNSKIKKTLLRYRNQIDDFDFS | maturation of SSU-rRNA ribosomal small subunit biogenesis rRNA processing 90S preribosome; Mpp10 complex; nucleolus; nucleoplasm; small ribosomal subunit; small-subunit processome rRNA binding snoRNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Nucleus Reference proteome Ribonucleop... |
dipeptide import across plasma membrane dipeptide transport peptide transport protein transport tripeptide transport | cell periphery; fungal-type vacuole; plasma membrane | dipeptide transmembrane transporter activity peptide transmembrane transporter activity tripeptide transmembrane transporter activity | Saccharomyces cerevisiae | Membrane Peptide transport Phosphoprotein Protein transport Reference proteome Transmembrane Transmembrane helix Transport | MLNHPSQGSD | MLNHPSQGSDDAQDEKQGDFPVIEEEKTQAVTLKDSYVSDDVANSTERYNLSPSPEDEDFEGPTEEEMQTLRHVGGKIPMRCWLIAIVELSERFSYYGLSAPFQNYMEYGPNDSPKGVLSLNSQGATGLSYFFQFWCYVTPVFGGYVADTFWGKYNTICCGTAIYIAGIFILFITSIPSVGNRDSAIGGFIAAIILIGIATGMIKANLSVLIADQLPKRKPSIKVLKSGERVIVDSNITLQNVFMFFYFMINVGSLSLMATTELEYHKGFWAAYLLPFCFFWIAVVTLIFGKKQYIQRPIGDKVIAKSFKVCWILTKNKF... | dipeptide import across plasma membrane dipeptide transport peptide transport protein transport tripeptide transport cell periphery; fungal-type vacuole; plasma membrane dipeptide transmembrane transporter activity peptide transmembrane transporter activity tripeptide transmembrane transporter activity Saccharomyces ce... |
cytoplasmic translation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly rRNA export fro... | 90S preribosome; cytoplasmic stress granule; cytosol; cytosolic small ribosomal subunit | structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Acetylation Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein Ribosome biogenesis rRNA processing | MSLPATFDLT | MSLPATFDLTPEDAQLLLAANTHLGARNVQVHQEPYVFNARPDGVHVINVGKTWEKLVLAARIIAAIPNPEDVVAISSRTFGQRAVLKFAAHTGATPIAGRFTPGSFTNYITRSFKEPRLVIVTDPRSDAQAIKEASYVNIPVIALTDLDSPSEFVDVAIPCNNRGKHSIGLIWYLLAREVLRLRGALVDRTQPWSIMPDLYFYRDPEEVEQQVAEEATTEEAGEEEAKEEVTEEQAEATEWAEENADNVEW | cytoplasmic translation endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly rRNA export fro... |
carbohydrate metabolic process protein deglycosylation involved in glycoprotein catabolic process protein glycosylation ubiquitin-dependent ERAD pathway | endoplasmic reticulum; endoplasmic reticulum membrane; membrane | calcium ion binding mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | Saccharomyces cerevisiae | 3D-structure Calcium Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Glycosidase Hydrolase Membrane Metal-binding Reference proteome Signal-anchor Transmembrane Transmembrane helix | MKNSVGISIA | MKNSVGISIATIVAIIAAIYYVPWYEHFERKSPGAGEMRDRIESMFLESWRDYSKHGWGYDVYGPIEHTSHNMPRGNQPLGWIIVDSVDTLMLMYNSSTLYKSEFEAEIQRSEHWINDVLDFDIDAEVNVFETTIRMLGGLLSAYHLSDVLEVGNKTVYLNKAIDLGDRLALAFLSTQTGIPYSSINLHSGQAVKNHADGGASSTAEFTTLQMEFKYLAYLTGNRTYWELVERVYEPLYKNNDLLNTYDGLVPIYTFPDTGKFGASTIRFGSRGDSFYEYLLKQYLLTHETLYYDLYRKSMEGMKKHLLAQSKPSSLWYI... | carbohydrate metabolic process protein deglycosylation involved in glycoprotein catabolic process protein glycosylation ubiquitin-dependent ERAD pathway endoplasmic reticulum; endoplasmic reticulum membrane; membrane calcium ion binding mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Saccharomyces cerevisiae 3... |
formation of translation preinitiation complex maintenance of translational fidelity regulation of translational fidelity | eukaryotic 43S preinitiation complex; multi-eIF complex | ribosomal small subunit binding RNA binding translation initiation factor activity translation initiation factor binding | Saccharomyces cerevisiae | 3D-structure Acetylation Protein biosynthesis Reference proteome Translation regulation | MSIENLKSFD | MSIENLKSFDPFADTGDDETATSNYIHIRIQQRNGRKTLTTVQGVPEEYDLKRILKVLKKDFACNGNIVKDPEMGEIIQLQGDQRAKVCEFMISQLGLQKKNIKIHGF | formation of translation preinitiation complex maintenance of translational fidelity regulation of translational fidelity eukaryotic 43S preinitiation complex; multi-eIF complex ribosomal small subunit binding RNA binding translation initiation factor activity translation initiation factor binding Saccharomyces cerevis... |
amphisome-lysosome fusion autophagosome-lysosome fusion cytoplasm to vacuole transport by the Cvt pathway intracellular protein transport macroautophagy piecemeal microautophagy of the nucleus vacuolar calcium ion homeostasis vacuole fusion, non-autophagic vesicle docking vesicle fusion | autophagosome membrane; endomembrane system; fungal-type vacuole membrane; phagophore assembly site; SNARE complex; vacuolar membrane | phosphatidylinositol-3-phosphate binding SNAP receptor activity SNARE binding | Saccharomyces cerevisiae | 3D-structure Coiled coil Reference proteome Vacuole | MAANSVGKMS | MAANSVGKMSEKLRIKVDDVKINPKYVLYGVSTPNKRLYKRYSEFWKLKTRLERDVGSTIPYDFPEKPGVLDRRWQRRYDDPEMIDERRIGLERFLNELYNDRFDSRWRDTKIAQDFLQLSKPNVSQEKSQQHLETADEVGWDEMIRDIKLDLDKESDGTPSVRGALRARTKLHKLRERLEQDVQKKSLPSTEVTRRAALLRSLLKECDDIGTANIAQDRGRLLGVATSDNSSTTEVQGRTNNDLQQGQMQMVRDQEQELVALHRIIQAQRGLALEMNEELQTQNELLTALEDDVDNTGRRLQIANKKARHFNNSA | amphisome-lysosome fusion autophagosome-lysosome fusion cytoplasm to vacuole transport by the Cvt pathway intracellular protein transport macroautophagy piecemeal microautophagy of the nucleus vacuolar calcium ion homeostasis vacuole fusion, non-autophagic vesicle docking vesicle fusion autophagosome membrane; endomemb... |
endocytic recycling intracellular protein transport retrograde transport, endosome to Golgi | cytosol; endomembrane system; endosome; retromer complex; retromer, tubulation complex | phosphatidylinositol-3-phosphate binding | Saccharomyces cerevisiae | 3D-structure Coiled coil Membrane Phosphoprotein Protein transport Reference proteome Transport | MTSAVPYDPY | MTSAVPYDPYDDLDNNPFAEPQEEDSEPAATTTDGSSSMSEERVGTEQTAASVQDNGTANNIQNGLGEEGNATRSKTSNEHNENQQPSQPSERVILPERSDEKKKYTLLAKVTGLERFGSATGKKENPTIIFDCSTNLPTFRKQQYKNVKKSYEEFHQLFKYLNVAIQESFVPTLPSAYTTFGINSEEDRMKVTRNFQLWFNRLSQDPLIIRNEEVAFFIESDFNTYTPINKSKSLASGLKRKTLKQLAPPYDEITELAEFRPLVKSIYVVSQSLQEKLLRVSRNRKMMVQEENAFGQDFVNLDEHNKLYRRYGKILTAV... | endocytic recycling intracellular protein transport retrograde transport, endosome to Golgi cytosol; endomembrane system; endosome; retromer complex; retromer, tubulation complex phosphatidylinositol-3-phosphate binding Saccharomyces cerevisiae 3D-structure Coiled coil Membrane Phosphoprotein Protein transport Referen... |
7-methylguanosine mRNA capping chromatin organization heterochromatin formation intracellular mRNA localization negative regulation of autophagy negative regulation of transcription elongation by RNA polymerase I positive regulation of transcription elongation by RNA polymerase I positive regulation of transcription el... | DSIF complex; kinetochore; nucleus | protein-containing complex binding rDNA binding RNA polymerase II complex binding zinc ion binding | Saccharomyces cerevisiae | 3D-structure Centromere Chromosome Metal-binding mRNA processing Nucleus Reference proteome Transcription Zinc Zinc-finger | MSSERACMLC | MSSERACMLCGIVQTTNEFNRDGCPNCQGIFEEAGVSTMECTSPSFEGLVGMCKPTKSWVAKWLSVDHSIAGMYAIKVDGRLPAEVVELLPHYKPRDGSQVE | 7-methylguanosine mRNA capping chromatin organization heterochromatin formation intracellular mRNA localization negative regulation of autophagy negative regulation of transcription elongation by RNA polymerase I positive regulation of transcription elongation by RNA polymerase I positive regulation of transcription el... |
misfolded protein transport post-translational protein targeting to membrane, translocation protein transmembrane import into intracellular organelle retrograde protein transport, ER to cytosol SRP-dependent cotranslational protein targeting to membrane, translocation ubiquitin-dependent ERAD pathway | endoplasmic reticulum; rough endoplasmic reticulum membrane; Sec61 translocon complex; translocon complex | peptide transmembrane transporter activity protein transmembrane transporter activity protein-transporting ATPase activity ribosome binding signal sequence binding | Saccharomyces cerevisiae | 3D-structure Endoplasmic reticulum Membrane Protein transport Reference proteome Translocation Transmembrane Transmembrane helix Transport | MSSNRVLDLF | MSSNRVLDLFKPFESFLPEVIAPERKVPYNQKLIWTGVSLLIFLILGQIPLYGIVSSETSDPLYWLRAMLASNRGTLLELGVSPIITSSMIFQFLQGTQLLQIRPESKQDRELFQIAQKVCAIILILGQALVVVMTGNYGAPSDLGLPICLLLIFQLMFASLIVMLLDELLSKGYGLGSGISLFTATNIAEQIFWRAFAPTTVNSGRGKEFEGAVIAFFHLLAVRKDKKRALVEAFYRTNLPNMFQVLMTVAIFLFVLYLQGFRYELPIRSTKVRGQIGIYPIKLFYTSNTPIMLQSALTSNIFLISQILFQKYPTNPLI... | misfolded protein transport post-translational protein targeting to membrane, translocation protein transmembrane import into intracellular organelle retrograde protein transport, ER to cytosol SRP-dependent cotranslational protein targeting to membrane, translocation ubiquitin-dependent ERAD pathway endoplasmic reticu... |
protein targeting to ER SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; signal recognition particle receptor complex | ATP hydrolysis activity GTP binding GTPase activity signal recognition particle binding | Saccharomyces cerevisiae | 3D-structure Endoplasmic reticulum GTP-binding Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome | MFDQLAVFTP | MFDQLAVFTPQGQVLYQYNCLGKKFSEIQINSFISQLITSPVTRKESVANANTDGFDFNLLTINSEHKNSPSFNALFYLNKQPELYFVVTFAEQTLELNQETQQTLALVLKLWNSLHLSESILKNRQGQNEKNKHNYVDILQGIEDDLKKFEQYFRIKYEESIKQDHINPDNFTKNGSVPQSHNKNTKKKLRDTKGKKQSTGNVGSGRKWGRDGGMLDEMNHEDAAKLDFSSSNSHNSSQVALDSTINKDSFGDRTEGGDFLIKEIDDLLSSHKDEITSGNEAKNSGYVSTAFGFLQKHVLGNKTINESDLKSVLEKLTQ... | protein targeting to ER SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition endoplasmic reticulum; endoplasmic reticulum membrane; membrane; signal recognition particle receptor complex ATP hydrolysis activity GTP binding GTPase activity signal recognition particle binding Saccharom... |
invasive growth in response to glucose limitation negative regulation of MAPK cascade pheromone-dependent signal transduction involved in conjugation with cellular fusion positive regulation of protein phosphorylation | cytoplasm; mating projection tip; mating projection tip membrane; nucleus; plasma membrane | G-protein beta-subunit binding kinase binding MAP-kinase scaffold activity phosphatidylinositol-4,5-bisphosphate binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Pheromone response Phosphoprotein Reference proteome | MMETPTDNIV | MMETPTDNIVSPFHNFGSSTQYSGTLSRTPNQIIELEKPSTLSPLSRGKKWTEKLARFQRSSAKKKRFSPSPISSSTFSFSPKSRVTSSNSSGNEDGNLMNTPSTVSTDYLPQHPHRTSSLPRPNSNLFHASNSNLSRANEPPRAENLSDNIPPKVAPFGYPIQRTSIKKSFLNASCTLCDEPISNRRKGEKIIELACGHLSHQECLIISFGTTSKADVRALFPFCTKCKKDTNKAVQCIPENDELKDILISDFLIHKIPDSELSITPQSRFPPYSPLLPPFGLSYTPVERQTIYSQAPSLNPNLILAAPPKERNQIPQK... | invasive growth in response to glucose limitation negative regulation of MAPK cascade pheromone-dependent signal transduction involved in conjugation with cellular fusion positive regulation of protein phosphorylation cytoplasm; mating projection tip; mating projection tip membrane; nucleus; plasma membrane G-protein b... |
angiogenesis positive regulation of gene expression positive regulation of protein-containing complex assembly regulation of angiogenesis tryptophanyl-tRNA aminoacylation | cytoplasm; cytosol; nucleus; protein-containing complex | ATP binding kinase inhibitor activity protein domain specific binding protein homodimerization activity protein kinase binding tryptophan-tRNA ligase activity | Mus musculus | Alternative splicing Aminoacyl-tRNA synthetase Angiogenesis ATP-binding Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome | MADMPSGESC | MADMPSGESCTSPLELFNSIATQGELVRSLKAGNAPKDEIDSAVKMLLSLKMSYKAAMGEEYKAGCPPGNPTAGRNCDSDATKASEDFVDPWTVRTSSAKGIDYDKLIVQFGSSKIDKELINRIERATGQRPHRFLRRGIFFSHRDMNQILDAYENKKPFYLYTGRGPSSEAMHLGHLVPFIFTKWLQDVFNVPLVIQMSDDEKYLWKDLTLEQAYSYTVENAKDIIACGFDINKTFIFSDLEYMGQSPGFYRNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAVQAAPSFSNSFPKIFRDRTDIQCLIPCAIDQDPY... | angiogenesis positive regulation of gene expression positive regulation of protein-containing complex assembly regulation of angiogenesis tryptophanyl-tRNA aminoacylation cytoplasm; cytosol; nucleus; protein-containing complex ATP binding kinase inhibitor activity protein domain specific binding protein homodimerizatio... |
cell-cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules | cornified envelope; cytosol; desmosome; extracellular exosome; plasma membrane | calcium ion binding | Homo sapiens | 3D-structure Calcium Cell adhesion Cell junction Cell membrane Cleavage on pair of basic residues Glycoprotein Membrane Metal-binding Reference proteome Repeat Signal Transmembrane Transmembrane helix | MMGLFPRTTG | MMGLFPRTTGALAIFVVVILVHGELRIETKGQYDEEEMTMQQAKRRQKREWVKFAKPCREGEDNSKRNPIAKITSDYQATQKITYRISGVGIDQPPFGIFVVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGADKDGEGLSTQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQT... | cell-cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules cornified envelope; cytosol; desmosome; extracellular exosome; plasma membrane calcium ion binding Homo sapiens 3D-structure Calcium Cell adhesion Cell junction Cell membrane Cleavage on pair of basic residues Glycoprotein Membrane Metal... |
cellular response to interleukin-3 cytokine-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway immunoglobulin mediated immune response interleukin-3-mediated signaling pathway interleukin-5-mediated signaling pathway positive regulation of leukocyte proliferation receptor sign... | external side of plasma membrane; granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane | coreceptor activity cytokine receptor activity signaling receptor activity | Homo sapiens | 3D-structure Alternative splicing Disulfide bond Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MVLAQGLLSM | MVLAQGLLSMALLALCWERSLAGAEETIPLQTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVNEDLLEPVSCDLSDDMPWSACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLGTRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQSHWLSPGDLEFEVVYKRLQDSWEDAAILLSNTSQATLGPEHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYI... | cellular response to interleukin-3 cytokine-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway immunoglobulin mediated immune response interleukin-3-mediated signaling pathway interleukin-5-mediated signaling pathway positive regulation of leukocyte proliferation receptor sign... |
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