Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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de novo' protein folding chaperone cofactor-dependent protein refolding mitochondrial genome maintenance protein quality control for misfolded or incompletely synthesized proteins protein refolding response to heat | cytoplasm; mitochondrial matrix; mitochondrion | ATP binding ATPase activator activity heat shock protein binding metal ion binding unfolded protein binding | Saccharomyces cerevisiae | Chaperone Metal-binding Mitochondrion Reference proteome Repeat Stress response Transit peptide Zinc Zinc-finger | MAFQQGVLSR | MAFQQGVLSRCSGVFRHHVGHSRHINNILYRHAIAFASIAPRIPKSSFHTSAIRNNEAFKDPYDTLGLKKSATGAEIKKAYYKLAKKYHPDINKEPDAEKKFHDLQNAYEILSDETKRQQYDQFGPAAFGGGGAAGGAGGGSGSPFGSQFHDFSGFTSAGGSPFGGINFEDLFGAAFGGGGRGSGGASRSSSMFRQYRGDPIEIVHKVSFKDAVFGSKNVQLRFSALDPCSTCSGTGMKPNTHKVSCSTCHGTGTTVHIRGGFQMMSTCPTCNGEGTMKRPQDNCTKCHGEGVQVNRAKTITVDLPHGLQDGDVVRIPGQ... | de novo' protein folding chaperone cofactor-dependent protein refolding mitochondrial genome maintenance protein quality control for misfolded or incompletely synthesized proteins protein refolding response to heat cytoplasm; mitochondrial matrix; mitochondrion ATP binding ATPase activator activity heat shock protein b... |
intracellular copper ion homeostasis intracellular iron ion homeostasis positive regulation of protein catabolic process positive regulation of transcription by RNA polymerase II | nucleus | cis-regulatory region sequence-specific DNA binding copper ion binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Saccharomyces cerevisiae | Activator Copper DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Zinc | MIIFNGNKYA | MIIFNGNKYACASCIRGHRSSTCRHSHRMLIKVRTRGRPSPMAIRDAILVDSTSQSTEYENGAQIEGDCCSAMNQQPILFVRASAVRKARMINGKLHILMEEGFTAHEPKDISTFTDDGNKYITETEFLRKHSPKAPATGTISPDSTKSSSSSEKKERSRLQQEPIRHFSNCCKKDKSQNPASNGKTNKAPSDDIFTPYGSLESTSAFNDILQENYNSSVPGAHDSSETLTPQSTTTIAAPHSSDVASKVEVLTHKGIFLSTQCSCEDESCPCVNCLIHRSEEELNSYIQQSGVPLTNIGEAQITDKMMDYLDDCKCTDK... | intracellular copper ion homeostasis intracellular iron ion homeostasis positive regulation of protein catabolic process positive regulation of transcription by RNA polymerase II nucleus cis-regulatory region sequence-specific DNA binding copper ion binding DNA-binding transcription activator activity, RNA polymerase I... |
autophagy protein transport protein-containing complex localization ubiquitin-dependent ERAD pathway vesicle organization | Cvt complex; cytoplasm; cytosol; phagophore assembly site; phagophore assembly site membrane | protein-macromolecule adaptor activity | Saccharomyces cerevisiae | 3D-structure Autophagy Coiled coil Isopeptide bond Membrane Phosphoprotein Protein transport Reference proteome Transport Ubl conjugation | MNNSKTNQQM | MNNSKTNQQMNTSMGYPLTVYDECNKFQLIVPTLDANIMLWCIGQLSLLNDSNGCKHLFWQPNDKSNVRILLNNYDYGHLFKYLQCQRKCSVYIGEGTLKKYNLTISTSFDNFLDLTPSEEKESLCREDAHEDPVSPKAGSEEEISPNSTSNVVVSRECLDNFMKQLLKLEESLNKLELEQKVTNKEPNHRISGTIDIPEDRSELVNFFTELKTVKQLEDVFQRYHDYERLSQECDSKTEIASDHSKKETKIEVEPPNERSLQITMNQRDNSLYFQLFNNTNSVLAGNCKLKFTDAGDKPTTQIIDMGPHEIGIKEYKEY... | autophagy protein transport protein-containing complex localization ubiquitin-dependent ERAD pathway vesicle organization Cvt complex; cytoplasm; cytosol; phagophore assembly site; phagophore assembly site membrane protein-macromolecule adaptor activity Saccharomyces cerevisiae 3D-structure Autophagy Coiled coil Isope... |
dolichol biosynthetic process endoplasmic reticulum to Golgi vesicle-mediated transport protein glycosylation | dehydrodolichyl diphosphate synthase complex; endoplasmic reticulum; endoplasmic reticulum membrane; lipid droplet | dehydrodolichyl diphosphate synthase activity polyprenyltransferase activity prenyltransferase activity | Saccharomyces cerevisiae | Endoplasmic reticulum Magnesium Membrane Reference proteome Transferase | METDSGIPGH | METDSGIPGHSFVLKWTKNIFSRTLRASNCVPRHVGFIMDGNRRFARKKEMDVKEGHEAGFVSMSRILELCYEAGVDTATVFAFSIENFKRSSREVESLMTLARERIRQITERGELACKYGVRIKIIGDLSLLDKSLLEDVRVAVETTKNNKRATLNICFPYTGREEILHAMKETIVQHKKGAAIDESTLESHLYTAGVPPLDLLIRTSGVSRLSDFLIWQASSKGVRIELLDCLWPEFGPIRMAWILLKFSFHKSFLNKEYRLEEGDYDEETNGDPIDLKEKKLN | dolichol biosynthetic process endoplasmic reticulum to Golgi vesicle-mediated transport protein glycosylation dehydrodolichyl diphosphate synthase complex; endoplasmic reticulum; endoplasmic reticulum membrane; lipid droplet dehydrodolichyl diphosphate synthase activity polyprenyltransferase activity prenyltransferase ... |
actin filament organization COPI coating of Golgi vesicle endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to plasma membrane protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | cytoskeleton; cytosol; endosome; Golgi membrane; mitochondrion; perinuclear region of cytoplasm; trans-Golgi network | actin binding GTPase activator activity metal ion binding | Saccharomyces cerevisiae | 3D-structure Cytoplasm Golgi apparatus GTPase activation Metal-binding Mitochondrion Phosphoprotein Protein transport Reference proteome Transport Zinc Zinc-finger | MSDWKVDPDT | MSDWKVDPDTRRRLLQLQKIGANKKCMDCGAPNPQWATPKFGAFICLECAGIHRGLGVHISFVRSITMDQFKPEELLRMEKGGNEPLTEWFKSHNIDLSLPQKVKYDNPVAEDYKEKLTCLCEDRVFEEREHLDFDASKLSATSQTAASATPGVAQSREGTPLENRRSATPANSSNGANFQKEKNEAYFAELGKKNQSRPDHLPPSQGGKYQGFGSTPAKPPQERSAGSSNTLSLENFQADPLGTLSRGWGLFSSAVTKSFEDVNETVIKPHVQQWQSGELSEETKRAAAQFGQKFQETSSYGFQAFSNFTKNFNGNAED... | actin filament organization COPI coating of Golgi vesicle endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to plasma membrane protein transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum cytoskeleton; cytosol; endosome; Golgi membrane; mitochondrion; perinuclear region of cytop... |
cardiolipin metabolic process cristae formation negative regulation of phosphatidylcholine biosynthetic process phosphatidylethanolamine metabolic process phospholipid transport | mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion | phosphatidic acid transfer activity | Saccharomyces cerevisiae | Membrane Mitochondrion Mitochondrion inner membrane Reference proteome | MKLFQNSYDF | MKLFQNSYDFNYPWDQVTAANWKKYPNEISTHVIAVDVLRRELKDQGKVLVTERLITVKQGVPKWIMMMLGGTNMSHVREVSVVDLNKKSLTMRSCNLTMCNLLKVYETVTYSPHPDDSANKTLFQQEAQITAYGSIRKLCNKMEDWSVQRFCENAKKGKMGFDAVLQVFSENWEKHVDDLSNQLVSKVNETMEDVKISAGTLLKGTERSGRTILQQNIDLFRDAYNHEN | cardiolipin metabolic process cristae formation negative regulation of phosphatidylcholine biosynthetic process phosphatidylethanolamine metabolic process phospholipid transport mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion phosphatidic acid transfer activity Saccharomyces cerevisiae M... |
attachment of mitotic spindle microtubules to kinetochore cell division chromosome segregation kinetochore assembly localization mitotic spindle organization spindle attachment to meiosis I kinetochore | condensed chromosome, centromeric region; kinetochore; nucleus | centromeric DNA binding protein-containing complex binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Cell division Centromere Chromosome DNA-binding Kinetochore Mitosis Nucleus Phosphoprotein Reference proteome Repeat | MDYMKLGLKS | MDYMKLGLKSRKTGIDVKQDIPKDEYSMENIDDFFKDDETSLISMRRKSRRKSSLFLPSTLNGDTKNVLPPFLQSYKSQDDEVVQSPSGKGDGSRRSSLLSHQSNFLSPANDFEPIEEEPEQEENDIRGNDFATPITQKLSKPTYKRKYSTRYSLDTSESPSVRLTPDRITNKNVYSDVPDLVADEDDDDRVNTSLNTSDNALLEDELEDDGFIPESEEDGDYIESDSSLDSGSDSASDSDGDNTYQEVEEEAEVNTNDNEDDYIRRQASDVVRTDSIIDRNGLRKSTRVKVAPLQYWRNEKIVYKRKSNKPVLDIDKIV... | attachment of mitotic spindle microtubules to kinetochore cell division chromosome segregation kinetochore assembly localization mitotic spindle organization spindle attachment to meiosis I kinetochore condensed chromosome, centromeric region; kinetochore; nucleus centromeric DNA binding protein-containing complex bind... |
kinetochore assembly septin ring assembly | CBF3 complex; kinetochore | DNA binding, bending | Saccharomyces cerevisiae | 3D-structure Centromere Chromosome Direct protein sequencing DNA-binding Nucleus Reference proteome | MPSFNPVRFL | MPSFNPVRFLELPIDIRKEVYFHLDGNFCGAHPYPIDILYKSNDVELPGKPSYKRSKRSKKLLRYMYPVFATYLNIFEYSPQLIEKWLEYAFWLRYDCLVLDCFKVNHLYDGTLIDALEWTYLDNELRLAYFNKASMLEVWYTFKEYKKWVIDSVAFDELDLLNVSNIQFNIDNLTPQLVDKCLSILEQKDLFATIGEVQFGQDEEVGEEKDVDVSGANSDENSSPSSTIKNKKRSASKRSHSDNGNVGATHNQLTSISVIRTIRSMESMKSLRKITVRGEKLYELLINFHGFRDNPGKTISYIVKRRINEIRLSRMNQI... | kinetochore assembly septin ring assembly CBF3 complex; kinetochore DNA binding, bending Saccharomyces cerevisiae 3D-structure Centromere Chromosome Direct protein sequencing DNA-binding Nucleus Reference proteome MPSFNPVRFL MPSFNPVRFLELPIDIRKEVYFHLDGNFCGAHPYPIDILYKSNDVELPGKPSYKRSKRSKKLLRYMYPVFATYLNIFEYSPQLIEKWLEYAFWL... |
glycosphingolipid biosynthetic process intracellular calcium ion homeostasis mannosyl diphosphorylinositol ceramide metabolic process | endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type vacuole; Golgi apparatus; mannosyltransferase complex | enzyme regulator activity | Saccharomyces cerevisiae | Endoplasmic reticulum Glycoprotein Membrane Reference proteome Signal Transmembrane Transmembrane helix | MSTTLLWFSS | MSTTLLWFSSVIGYVIQTKCLSNIQSKKEISVGPNGTIATPETNGDNGNSSSLTFYLTFMYFASWLLLVPASRLWEKMRPMFVSDSDSNRNSQFDNNNSGSVTNEDVDTFSHVLDDPQPRIPAQQQKQKIISVATFKYVAKLTVLALIMIVADLTYNMALSLSPAFDVALMQNTAIFEIVTLLYGVCGISRKNYVFRNFLIMMNAVIGILIISYTKATCDMLAGKLSVNPNTGELSDPFLFDRLKGALICGLGALIMGPFAVLWNRWFCSNISKNENSAVVLVKQSTHMALIGIIGMVILLPFIPKFPSRESVESISLFY... | glycosphingolipid biosynthetic process intracellular calcium ion homeostasis mannosyl diphosphorylinositol ceramide metabolic process endoplasmic reticulum; endoplasmic reticulum membrane; fungal-type vacuole; Golgi apparatus; mannosyltransferase complex enzyme regulator activity Saccharomyces cerevisiae Endoplasmic r... |
DNA repair negative regulation of autophagy negative regulation of transcription by RNA polymerase II rDNA heterochromatin formation silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation | chromosome, telomeric region; nucleus | acyltransferase activity, transferring groups other than amino-acyl groups promoter-specific chromatin binding sequence-specific DNA binding | Saccharomyces cerevisiae | Reference proteome | MLNQHTSSVP | MLNQHTSSVPDDEHLQMAHQNSSSEVRNEAAVPDQLLTPLQPYTILLKDGETIATMYPIPAYPDLLPLGLLNFLLDEFNMEVEKGDSFPYYETLSLEEFKNVWFHNDGHVCIMVLGEIPELDYSMDTEADTNDNFGTEIETTKHTTQYKKRKERRNLNLSMQWEKQCLGIFDLKPAYPGRSAHVVTGTFLVNAGIRGKGIGKTLMETFIEWSKKLGFTSSFFPLIYGTNVGIRRILEGLNFRRIGKLPEAGILKGFDVPVDSFMYGKEFTHITKSIDLLRDPQKSIEIGKYERLKHFLETGKYPLHCDRNEKARLRVLSK... | DNA repair negative regulation of autophagy negative regulation of transcription by RNA polymerase II rDNA heterochromatin formation silent mating-type cassette heterochromatin formation subtelomeric heterochromatin formation chromosome, telomeric region; nucleus acyltransferase activity, transferring groups other than... |
blood vessel development calcium ion transport cell-cell junction assembly cell-cell signaling endothelium development response to pain | connexin complex; gap junction; plasma membrane | gap junction channel activity | Homo sapiens | Cell junction Cell membrane Gap junction Membrane Reference proteome Transmembrane Transmembrane helix | MGDWGFLEKL | MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRARQGQDAPPTQGTSSDPYTDQVFFYLPVGQGPSSPPCPTYNGLSSSEQNWANLTTEERLASSRPPLFLDPPPQNGQKPP... | blood vessel development calcium ion transport cell-cell junction assembly cell-cell signaling endothelium development response to pain connexin complex; gap junction; plasma membrane gap junction channel activity Homo sapiens Cell junction Cell membrane Gap junction Membrane Reference proteome Transmembrane Transmembr... |
cytoplasmic sequestering of protein negative regulation of DNA-templated transcription negative regulation of G protein-coupled receptor signaling pathway negative regulation of protein dephosphorylation protein targeting signal transduction | cytoplasm; cytosol; melanosome; perinuclear region of cytoplasm; protein-containing complex; transcription repressor complex | enzyme binding histone deacetylase binding identical protein binding phosphoprotein binding phosphoserine residue binding protein domain specific binding protein kinase inhibitor activity protein-containing complex binding | Rattus norvegicus | Acetylation Alternative initiation Cytoplasm Direct protein sequencing Isopeptide bond Nitration Phosphoprotein Reference proteome Ubl conjugation | MTMDKSELVQ | MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICSDVLELLDKYLILNATHAESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN | cytoplasmic sequestering of protein negative regulation of DNA-templated transcription negative regulation of G protein-coupled receptor signaling pathway negative regulation of protein dephosphorylation protein targeting signal transduction cytoplasm; cytosol; melanosome; perinuclear region of cytoplasm; protein-conta... |
one-carbon metabolic process | cytoplasm; mitochondrial matrix; mitochondrion | carbonate dehydratase activity zinc ion binding | Homo sapiens | Direct protein sequencing Disease variant Lyase Metal-binding Mitochondrion Reference proteome Transit peptide Zinc | MLGRNTWKTS | MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATNEGTRS | one-carbon metabolic process cytoplasm; mitochondrial matrix; mitochondrion carbonate dehydratase activity zinc ion binding Homo sapiens Direct protein sequencing Disease variant Lyase Metal-binding Mitochondrion Reference proteome Transit peptide Zinc MLGRNTWKTS MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPV... |
one-carbon metabolic process positive regulation of calcium-mediated signaling | cytoplasm | carbonate dehydratase activity hydro-lyase activity zinc ion binding | Homo sapiens | 3D-structure Disease variant Intellectual disability Metal-binding Phosphoprotein Reference proteome Zinc | MADLSFIEDT | MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ | one-carbon metabolic process positive regulation of calcium-mediated signaling cytoplasm carbonate dehydratase activity hydro-lyase activity zinc ion binding Homo sapiens 3D-structure Disease variant Intellectual disability Metal-binding Phosphoprotein Reference proteome Zinc MADLSFIEDT MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYE... |
adherens junction assembly adherens junction organization apical constriction cell migration cell-cell adhesion dorsal closure, amnioserosa morphology change head morphogenesis | actin cytoskeleton; adherens junction; catenin complex; cytoplasm; plasma membrane | actin filament binding beta-catenin binding cadherin binding identical protein binding structural molecule activity | Drosophila melanogaster | Cell adhesion Cell junction Cell membrane Cytoplasm Cytoskeleton Membrane Phosphoprotein Reference proteome | MLKPDKMGTL | MLKPDKMGTLTDFGQIALKWDPKNLEIRTMSVEKTLEPLVLQVTTLVNTKGPSKKKKGKSKRASALVAAVEKATENFIQKGEQIAYENPDITQEMLTAVDEVKKTGDAMSIAAREFSEDPCSSLKRGNMVRAARNLLSAVTRLLILADMVDVHLLLKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKRQQELKDPQLRDDLAAARAMLKKHSTMLLTASKVYVRHPELDLAKVNRDFILKQVCDAVNTISDVAQGKSSQPTDIYSGAGELAAALDDFDEGIVMDPMTYSEKRSRQLLEERLESIISAAA... | adherens junction assembly adherens junction organization apical constriction cell migration cell-cell adhesion dorsal closure, amnioserosa morphology change head morphogenesis actin cytoskeleton; adherens junction; catenin complex; cytoplasm; plasma membrane actin filament binding beta-catenin binding cadherin binding... |
apical junction assembly axon regeneration cell adhesion cell migration cell-cell adhesion cellular response to indole-3-methanol epithelial cell-cell adhesion establishment or maintenance of cell polarity extrinsic apoptotic signaling pathway in absence of ligand gap junction assembly integrin-mediated signaling pathw... | acrosomal vesicle; actin cytoskeleton; adherens junction; catenin complex; cell junction; cell-cell junction; cytosol; flotillin complex; focal adhesion; intercalated disc; intracellular membrane-bounded organelle; lamellipodium; plasma membrane; zonula adherens | actin filament binding beta-catenin binding cadherin binding gamma-catenin binding identical protein binding RNA binding structural molecule activity vinculin binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cell adhesion Cell junction Cell membrane Cytoplasm Cytoskeleton Direct protein sequencing Isopeptide bond Membrane Phosphoprotein Reference proteome Ubl conjugation | MTAVHAGNIN | MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMA... | apical junction assembly axon regeneration cell adhesion cell migration cell-cell adhesion cellular response to indole-3-methanol epithelial cell-cell adhesion establishment or maintenance of cell polarity extrinsic apoptotic signaling pathway in absence of ligand gap junction assembly integrin-mediated signaling pathw... |
apoptotic signaling pathway brain development chromatin remodeling DNA methylation embryonic skeletal system morphogenesis hemopoiesis humoral immune response in utero embryonic development negative regulation of apoptotic signaling pathway negative regulation of gene expression, epigenetic negative regulation of trans... | cytosol; heterochromatin; nuclear body; nucleoplasm; nucleus; PcG protein complex; PRC1 complex; ubiquitin ligase complex | promoter-specific chromatin binding RING-like zinc finger domain binding RNA polymerase II cis-regulatory region sequence-specific DNA binding ubiquitin-protein transferase activator activity zinc ion binding | Homo sapiens | 3D-structure Chromatin regulator Cytoplasm Metal-binding Nucleus Proto-oncogene Reference proteome Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MHRTTRIKIT | MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQRDGLTNAGELESDSGSDKANSPAGGIPSTSSCLPSPSTPVQSPHPQFPHISSTMNGTSNSPSGNHQSSFANRPRKSSVNGS... | apoptotic signaling pathway brain development chromatin remodeling DNA methylation embryonic skeletal system morphogenesis hemopoiesis humoral immune response in utero embryonic development negative regulation of apoptotic signaling pathway negative regulation of gene expression, epigenetic negative regulation of trans... |
anterior/posterior pattern specification apoptotic signaling pathway cellular response to hydrogen peroxide chromatin remodeling embryonic skeletal system morphogenesis in utero embryonic development negative regulation of apoptotic signaling pathway negative regulation of transcription by RNA polymerase II | chromatin; nuclear body; nucleoplasm; nucleus; PcG protein complex; PRC1 complex; sex chromatin | DNA binding metal ion binding promoter-specific chromatin binding | Homo sapiens | Disease variant DNA-binding Intellectual disability Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MHRTTRIKIT | MHRTTRIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALSDDEIVSLSIEFYEGARDRDEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRLTLATVPTPSEGTNTSGASECESVSDKAPSPATLPATSSSLPSPATPSHGSPSSHGPPATHPTSPTPPSTASGATTAANGGSLNC... | anterior/posterior pattern specification apoptotic signaling pathway cellular response to hydrogen peroxide chromatin remodeling embryonic skeletal system morphogenesis in utero embryonic development negative regulation of apoptotic signaling pathway negative regulation of transcription by RNA polymerase II chromatin; ... |
acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of cell wall in another organism negative regulation of cellular response to oxidative stress positive regulation of cell popula... | apical part of cell; collagen-containing extracellular matrix; extracellular space; protein-containing complex; zymogen granule | growth factor binding hormone activity identical protein binding metal ion binding oligosaccharide binding peptidoglycan binding signaling receptor activity | Mus musculus | Acute phase Antimicrobial Disulfide bond Inflammatory response Lectin Metal-binding Reference proteome Secreted Signal Zinc | MLPPTACSVM | MLPPTACSVMSWMLLSCLMLLSQVQGEDSLKNIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPGGHLVSVLNSAEASFLSSMVKRTGNSYQYTWIGLHDPTLGAEPNGGGWEWSNNDVMNYFNWERNPSTALDRAFCGSLSRASGFLKWRDMTCEVKLPYVCKFTG | acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of cell wall in another organism negative regulation of cellular response to oxidative stress positive regulation of cell popula... |
acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide disruption of cell wall in another organism negative regulation of keratinocyte differentiation positive regulation of cell population proliferation positive regulation of keratinocyte proliferation positive regulation of wound... | extracellular space | metal ion binding oligosaccharide binding peptidoglycan binding signaling receptor activity | Rattus norvegicus | Acute phase Antimicrobial Disulfide bond Inflammatory response Lectin Metal-binding Reference proteome Secreted Signal Zinc | MLPRLSFNNV | MLPRLSFNNVSWTLLYYLFIFQVRGEDSQKAVPSTRTSCPMGSKAYRSYCYTLVTTLKSWFQADLACQKRPSGHLVSILSGGEASFVSSLVTGRVNNNQDIWIWLHDPTMGQQPNGGGWEWSNSDVLNYLNWDGDPSSTVNRGNCGSLTATSEFLKWGDHHCDVELPFVCKFKQ | acute-phase response antimicrobial humoral immune response mediated by antimicrobial peptide disruption of cell wall in another organism negative regulation of keratinocyte differentiation positive regulation of cell population proliferation positive regulation of keratinocyte proliferation positive regulation of wound... |
dephosphorylation exploration behavior positive regulation of long-term synaptic potentiation positive regulation of neuron projection development positive regulation of protein import into nucleus positive regulation of protein phosphorylation positive regulation of protein targeting to mitochondrion positive regulati... | axon; cell junction; cytosol; neuronal cell body; perikaryon; plasma membrane; proximal dendrite; synaptic membrane; synaptic vesicle | identical protein binding phosphotyrosine residue binding protein kinase binding protein tyrosine phosphatase activity | Rattus norvegicus | Cytoplasm Hydrolase Phosphoprotein Protein phosphatase Reference proteome | MEEKVEDDFL | MEEKVEDDFLDLDAVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLVSPREESAHEYLLSASRVLRAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVRLTSPDPEDPLSSYINANYIRGYNGEEKVYIATQGPIVSTVVDFWRMVWQERTPIIVMITNIEEMNEKCTEYWPEEQVVHDGVEITVQKVIHTEDYRLRLISLRRGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATSICCQQL... | dephosphorylation exploration behavior positive regulation of long-term synaptic potentiation positive regulation of neuron projection development positive regulation of protein import into nucleus positive regulation of protein phosphorylation positive regulation of protein targeting to mitochondrion positive regulati... |
MAPK cascade protein dephosphorylation | cytoplasm; cytoplasmic side of plasma membrane; cytosol; microtubule cytoskeleton; mitotic spindle; nucleoplasm | non-membrane spanning protein tyrosine phosphatase activity protein tyrosine phosphatase activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Cytoskeleton Hydrolase Oxidation Phosphoprotein Protein phosphatase Reference proteome | MVQAHGGRSR | MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDIL... | MAPK cascade protein dephosphorylation cytoplasm; cytoplasmic side of plasma membrane; cytosol; microtubule cytoskeleton; mitotic spindle; nucleoplasm non-membrane spanning protein tyrosine phosphatase activity protein tyrosine phosphatase activity Homo sapiens 3D-structure Alternative splicing Cytoplasm Cytoskeleton H... |
cellular response to osmotic stress negative regulation of endopeptidase activity sensory perception of sound | collagen-containing extracellular matrix; cytoplasm; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule membrane; plasma membrane; secretory granule membrane; serine protease inhibitor complex; tertiary granule membrane | protease binding serine-type endopeptidase inhibitor activity | Homo sapiens | Acetylation Cytoplasm Deafness Direct protein sequencing Non-syndromic deafness Phosphoprotein Protease inhibitor Reference proteome Serine protease inhibitor | MDVLAEANGT | MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTDLSLSKVVHKSF... | cellular response to osmotic stress negative regulation of endopeptidase activity sensory perception of sound collagen-containing extracellular matrix; cytoplasm; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule membrane; plasma membrane; secretory granule membrane; seri... |
phototransduction regulation of calcium ion transport signal transduction visual perception | dendrite; membrane; perikaryon; photoreceptor inner segment; photoreceptor outer segment | calcium ion binding calcium sensitive guanylate cyclase activator activity | Homo sapiens | 3D-structure Calcium Cell projection Direct protein sequencing Disulfide bond Lipoprotein Membrane Metal-binding Myristate Oxidation Redox-active center Reference proteome Repeat Sensory transduction Vision | MGNSKSGALS | MGNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQFEPQKVKEKMKNA | phototransduction regulation of calcium ion transport signal transduction visual perception dendrite; membrane; perikaryon; photoreceptor inner segment; photoreceptor outer segment calcium ion binding calcium sensitive guanylate cyclase activator activity Homo sapiens 3D-structure Calcium Cell projection Direct protein... |
base-excision repair DNA repair DNA replication double-strand break repair via homologous recombination mismatch repair nucleotide-excision repair regulation of cell population proliferation regulation of mitotic cell cycle telomere maintenance | DNA replication factor A complex; nucleoplasm; site of double-strand break | damaged DNA binding single-stranded DNA binding | Homo sapiens | 3D-structure Acetylation DNA damage DNA recombination DNA repair DNA replication Isopeptide bond Nucleus Reference proteome Ubl conjugation | MVDMMDLPRS | MVDMMDLPRSRINAGMLAQFIDKPVCFVGRLEKIHPTGKMFILSDGEGKNGTIELMEPLDEEISGIVEVVGRVTAKATILCTSYVQFKEDSHPFDLGLYNEAVKIIHDFPQFYPLGIVQHD | base-excision repair DNA repair DNA replication double-strand break repair via homologous recombination mismatch repair nucleotide-excision repair regulation of cell population proliferation regulation of mitotic cell cycle telomere maintenance DNA replication factor A complex; nucleoplasm; site of double-strand break ... |
innate immune response lung alveolus development positive regulation of immune response positive regulation of phagocytosis respiratory gaseous exchange by respiratory system surfactant homeostasis | collagen trimer; extracellular space; multivesicular body | carbohydrate binding | Bos taurus | Calcium Coiled coil Collagen Direct protein sequencing Disulfide bond Extracellular matrix Gaseous exchange Glycoprotein Hydroxylation Immunity Innate immunity Lectin Reference proteome Repeat S-nitrosylation Secreted Signal Surface film | MLLLPLSVLL | MLLLPLSVLLLLTQPWRSLGAEMKIYSQKTMANACTLVMCSPPEDGLPGRDGRDGREGPRGEKGDPGSPGPAGRAGMPGPAGPIGLKGDNGSAGEPGPKGDTGPPGPPGMPGPAGREGPSGKQGSMGPPGTPGPKGDTGPKGGVGAPGIQGSPGPAGLKGERGAPGEPGAPGRAGAPGPAGAIGPQGPSGARGPPGLKGDRGTPGERGAKGESGLAEVNALRQRVGILEGQLQRLQNAFSQYKKAMLFPNGRSVGEKIFKTEGSEKTFQDAQQICTQAGGQLPSPRSAAENEALTQLATAQNKAAFLSMSDTRKEGTFIY... | innate immune response lung alveolus development positive regulation of immune response positive regulation of phagocytosis respiratory gaseous exchange by respiratory system surfactant homeostasis collagen trimer; extracellular space; multivesicular body carbohydrate binding Bos taurus Calcium Coiled coil Collagen Dir... |
defense response to bacterium innate immune response lung alveolus development macrophage chemotaxis negative regulation of interleukin-2 production negative regulation of T cell proliferation positive regulation of phagocytosis reactive oxygen species metabolic process receptor-mediated endocytosis regulation of cytok... | clathrin-coated endocytic vesicle; collagen trimer; endocytic vesicle; endoplasmic reticulum membrane; extracellular region; extracellular space; lysosome; multivesicular body | carbohydrate binding identical protein binding | Homo sapiens | 3D-structure Calcium Coiled coil Collagen Direct protein sequencing Disulfide bond Extracellular matrix Gaseous exchange Glycoprotein Hydroxylation Immunity Innate immunity Lectin Reference proteome Repeat S-nitrosylation Secreted Signal Surface film | MLLFLLSALV | MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKT... | defense response to bacterium innate immune response lung alveolus development macrophage chemotaxis negative regulation of interleukin-2 production negative regulation of T cell proliferation positive regulation of phagocytosis reactive oxygen species metabolic process receptor-mediated endocytosis regulation of cytok... |
innate immune response lung alveolus development negative regulation of interleukin-2 production negative regulation of phagocytosis negative regulation of T cell proliferation opsonization positive regulation of phagocytosis respiratory gaseous exchange by respiratory system response to glucocorticoid response to grow... | collagen trimer; cytoplasm; extracellular space; multivesicular body | identical protein binding lipopolysaccharide binding monosaccharide binding | Rattus norvegicus | Calcium Coiled coil Collagen Direct protein sequencing Disulfide bond Extracellular matrix Gaseous exchange Glycoprotein Hydroxylation Immunity Innate immunity Lectin Phosphoprotein Reference proteome Repeat S-nitrosylation Secreted Signal Surface film | MLHFLSMLVL | MLHFLSMLVLLVQPLGDLGAEMKTLSQRSITNTCTLVLCSPTENGLPGRDGRDGREGPRGEKGDPGLPGPMGLSGLPGPRGPVGPKGENGSAGEPGPKGERGLVGPPGSPGISGPAGKEGPSGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGAKGPAGPKGERGAPGEQGAPGNAGAAGPAGPAGPQGAPGSRGPPGLKGDRGAPGDRGIKGESGLPDSAALRQQMEALNGKLQRLEAAFSRYKKAALFPDGQSVGDKIFRAANSEEPFEDAKEMCRQAGGQLASPRSATENAAVQQLVTAHSKAAFLSMTDVGTE... | innate immune response lung alveolus development negative regulation of interleukin-2 production negative regulation of phagocytosis negative regulation of T cell proliferation opsonization positive regulation of phagocytosis respiratory gaseous exchange by respiratory system response to glucocorticoid response to grow... |
DNA duplex unwinding DNA repair DNA strand elongation involved in DNA replication DNA-templated DNA replication positive regulation of DNA-directed DNA polymerase activity | Ctf18 RFC-like complex; DNA replication factor C complex; Elg1 RFC-like complex; nucleoplasm; nucleus | ATP binding ATP hydrolysis activity DNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Direct protein sequencing DNA replication Nucleotide-binding Nucleus Reference proteome | MQAFLKGTSI | MQAFLKGTSISTKPPLTKDRGVAASAGSSGENKKAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLDIAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEKIDGVFAACQSGSFDKLEAVVKDLIDEGHAATQLVNQLHDVVVENNLS... | DNA duplex unwinding DNA repair DNA strand elongation involved in DNA replication DNA-templated DNA replication positive regulation of DNA-directed DNA polymerase activity Ctf18 RFC-like complex; DNA replication factor C complex; Elg1 RFC-like complex; nucleoplasm; nucleus ATP binding ATP hydrolysis activity DNA bindin... |
DNA duplex unwinding DNA repair DNA-templated DNA replication positive regulation of DNA-directed DNA polymerase activity | Ctf18 RFC-like complex; DNA replication factor C complex; nucleoplasm; nucleus | ATP binding ATP hydrolysis activity DNA binding enzyme binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Direct protein sequencing DNA replication Nucleotide-binding Nucleus Phosphoprotein Reference proteome Williams-Beuren syndrome | MEVEAVCGGA | MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEI... | DNA duplex unwinding DNA repair DNA-templated DNA replication positive regulation of DNA-directed DNA polymerase activity Ctf18 RFC-like complex; DNA replication factor C complex; nucleoplasm; nucleus ATP binding ATP hydrolysis activity DNA binding enzyme binding Homo sapiens 3D-structure Acetylation Alternative splici... |
disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity suppression by virus of host type I interferon-mediated signaling pathway viral budding from plasma membrane viral budding via host ESCRT complex | host cell endomembrane system; host cell late endosome membrane; host cell plasma membrane; membrane; virion membrane | structural constituent of virion | Lake Victoria marburgvirus ) | 3D-structure Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host JAK1 by virus Membrane Reference proteome Viral budding Viral budding via the host ESCRT complexes Viral immun... | MASSSNYNTY | MASSSNYNTYMQYLNPPPYADHGANQLIPADQLSNQQGITPNYVGDLNLDDQFKGNVCHAFTLEAIIDISAYNERTVKGVPAWLPLGIMSNFEYPLAHTVAALLTGSYTITQFTHNGQKFVRVNRLGTGIPAHPLRMLREGNQAFIQNMVIPRNFSTNQFTYNLTNLVLSVQKLPDDAWRPSKDKLIGNTMHPAVSIHPNLPPIVLPTVKKQAYRQHKNPNNGPLLAISGILHQLRVEKVPEKTSLFRISLPADMFSVKEGMMKKRGENSPVVYFQAPENFPLNGFNNRQVVLAYANPTLSAV | disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity suppression by virus of host type I interferon-mediated signaling pathway viral budding from plasma membrane viral budding via host ESCRT complex host cell endomembrane system; host cell late endosome membrane; host cell plasma membrane; membr... |
alpha-beta T cell differentiation cytoplasmic translation translation translation at presynapse | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; extracellular exosome; focal adhesion; glutamatergic synapse; nucleus; presynapse; ribonucleoprotein complex | heparin binding identical protein binding RNA binding structural constituent of ribosome | Homo sapiens | 3D-structure Cytoplasm Direct protein sequencing Heparin-binding Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding | MAPVKKLVVK | MAPVKKLVVKGGKKKKQVLKFTLDCTHPVEDGIMDAANFEQFLQERIKVNGKAGNLGGGVVTIERSKSKITVTSEVPFSKRYLKYLTKKYLKKNNLRDWLRVVANSKESYELRYFQINQDEEEEEDED | alpha-beta T cell differentiation cytoplasmic translation translation translation at presynapse cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; extracellular exosome; focal adhesion; glutamatergic synapse; nucleus; presynapse; ribonucleoprotein complex heparin binding identical protein bindin... |
negative regulation of protein binding positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II response to virus transcription by RNA polymerase II transcription elongation by RNA polymerase II transcription initiation at RNA polymerase II promoter | cell junction; intracellular membrane-bounded organelle; nucleoplasm; nucleus; protein-containing complex; transcription factor TFIID complex; transcription factor TFIIF complex | DNA binding phosphatase activator activity promoter-specific chromatin binding protein domain specific binding protein phosphatase binding RNA binding RNA polymerase II general transcription initiation factor activity RNA polymerase II general transcription initiation factor binding TFIIF-class transcription factor com... | Homo sapiens | 3D-structure Acetylation Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MAALGPSSQN | MAALGPSSQNVTEYVVRVPKNTTKKYNIMAFNAADKVNFATWNQARLERDLSNKKIYQEEEMPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEED... | negative regulation of protein binding positive regulation of transcription by RNA polymerase II positive regulation of transcription elongation by RNA polymerase II response to virus transcription by RNA polymerase II transcription elongation by RNA polymerase II transcription initiation at RNA polymerase II promoter ... |
nitric oxide biosynthetic process tetrahydrobiopterin biosynthetic process | cytosol; extracellular exosome; nucleoplasm | aldo-keto reductase (NADP) activity NADP binding sepiapterin reductase activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Disease variant Dystonia NADP Oxidoreductase Phosphoprotein Reference proteome | MEGGLGRAVC | MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK | nitric oxide biosynthetic process tetrahydrobiopterin biosynthetic process cytosol; extracellular exosome; nucleoplasm aldo-keto reductase (NADP) activity NADP binding sepiapterin reductase activity Homo sapiens 3D-structure Acetylation Cytoplasm Disease variant Dystonia NADP Oxidoreductase Phosphoprotein Reference pro... |
bone resorption positive regulation of regulated secretory pathway protein localization to plasma membrane protein secretion regulation of exocytosis vesicle docking involved in exocytosis | cytoplasmic microtubule; endosome; mitochondrion; plasma membrane; secretory vesicle; synaptic vesicle; zymogen granule | GTP binding GTP-dependent protein binding GTPase activity myosin V binding | Mus musculus | Acetylation Cell membrane Direct protein sequencing Exocytosis GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MASASEPPAS | MASASEPPASPRDAADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFTAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDIICDKMNESLEPSSSPGSNGKGPALGDTPPPQPSSCSC | bone resorption positive regulation of regulated secretory pathway protein localization to plasma membrane protein secretion regulation of exocytosis vesicle docking involved in exocytosis cytoplasmic microtubule; endosome; mitochondrion; plasma membrane; secretory vesicle; synaptic vesicle; zymogen granule GTP binding... |
endocytosis endosome organization intracellular protein transport plasma membrane to endosome transport regulation of endocytosis | early endosome membrane; endocytic vesicle; endomembrane system; endosome; lipid droplet; melanosome; plasma membrane; synaptic vesicle membrane | G protein activity GDP binding GTP binding GTPase activity | Mus musculus | 3D-structure Cell membrane Direct protein sequencing Endosome GTP-binding Hydrolase Lipoprotein Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MAGRGGAARP | MAGRGGAARPNGPAAGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNTDTFARAKNWVKELQRQASPNIVIALAGNKADLASKRAVEFQEAQAYADDNSLLFMETSAKTAMNVNEIFMAIAKKLPKNEPQNAAGAPGRTRGVDLQESNPASRSQCCSN | endocytosis endosome organization intracellular protein transport plasma membrane to endosome transport regulation of endocytosis early endosome membrane; endocytic vesicle; endomembrane system; endosome; lipid droplet; melanosome; plasma membrane; synaptic vesicle membrane G protein activity GDP binding GTP binding GT... |
antigen processing and presentation early endosome to Golgi transport intra-Golgi vesicle-mediated transport intracellular protein transport localization protein localization to Golgi apparatus protein localization to Golgi membrane retrograde transport, endosome to Golgi retrograde vesicle-mediated transport, Golgi to... | acrosomal membrane; cytoplasmic vesicle; cytosol; endomembrane system; endosome to plasma membrane transport vesicle; Golgi apparatus; Golgi membrane; membrane; presynapse; trans-Golgi network | ATPase activator activity ATPase binding GTP binding GTPase activity myosin V binding protein domain specific binding | Mus musculus | Acetylation Alternative splicing Cytoplasmic vesicle Direct protein sequencing ER-Golgi transport Golgi apparatus GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MSAGGDFGNP | MSAGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVNEGGCSC | antigen processing and presentation early endosome to Golgi transport intra-Golgi vesicle-mediated transport intracellular protein transport localization protein localization to Golgi apparatus protein localization to Golgi membrane retrograde transport, endosome to Golgi retrograde vesicle-mediated transport, Golgi to... |
autophagy axonogenesis cellular response to insulin stimulus cilium assembly endocytic recycling glucose homeostasis Golgi organization Golgi vesicle fusion to target membrane neurotransmitter receptor transport to postsynaptic membrane neurotransmitter receptor transport, endosome to postsynaptic membrane positive reg... | centriole; centrosome; ciliary basal body; ciliary base; ciliary membrane; cilium; cytoplasmic vesicle; cytoplasmic vesicle membrane; dendrite; dendritic spine; endosome; endosome membrane; glutamatergic synapse; Golgi apparatus; midbody; neuron projection; neuronal cell body; non-motile cilium; phagocytic vesicle; pha... | GDP binding GTP binding GTPase activity myosin V binding protein kinase binding protein tyrosine kinase binding | Rattus norvegicus | Autophagy Cell membrane Cell projection Cilium Cilium biogenesis/degradation Cytoplasm Cytoplasmic vesicle Cytoskeleton Endosome Golgi apparatus GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MAKTYDYLFK | MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGNSPQGSSHGVKITVEQQKRTSFFRCSLL | autophagy axonogenesis cellular response to insulin stimulus cilium assembly endocytic recycling glucose homeostasis Golgi organization Golgi vesicle fusion to target membrane neurotransmitter receptor transport to postsynaptic membrane neurotransmitter receptor transport, endosome to postsynaptic membrane positive reg... |
antigen processing and presentation axonogenesis cellular response to antibiotic cellular response to insulin stimulus endoplasmic reticulum tubular network organization endosomal transport establishment of neuroblast polarity establishment of protein localization to endoplasmic reticulum membrane establishment of prot... | cilium; endoplasmic reticulum membrane; endoplasmic reticulum tubular network; endosome; endosome membrane; exocytic vesicle; Golgi apparatus; insulin-responsive compartment; perinuclear region of cytoplasm; phagocytic vesicle membrane; recycling endosome; recycling endosome membrane; synaptic vesicle membrane; trans-G... | G protein activity GDP binding GDP-dissociation inhibitor binding GTP binding myosin V binding | Rattus norvegicus | Acetylation Cell projection Cytoplasm Cytoplasmic vesicle Endoplasmic reticulum Endosome Golgi apparatus GTP-binding Hydrolase Isopeptide bond Lipoprotein Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport Ubl conjugation | MAKKTYDLLF | MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIEIDFKIKTVELQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDQHANEDVERMLLRNKCDMDHKRVVPKGKGEQIAREHRIRFFETSAKANINIEKAFLTLPEDILRKTPVKEPNSENVDISSGGGVTGWKSKCC | antigen processing and presentation axonogenesis cellular response to antibiotic cellular response to insulin stimulus endoplasmic reticulum tubular network organization endosomal transport establishment of neuroblast polarity establishment of protein localization to endoplasmic reticulum membrane establishment of prot... |
anterograde axonal transport intracellular protein transport positive regulation of dendrite morphogenesis positive regulation of early endosome to late endosome transport positive regulation of receptor-mediated endocytosis protein stabilization Rab protein signal transduction regulation of axon extension regulation o... | axon cytoplasm; cleavage furrow; cytoplasmic side of early endosome membrane; cytoplasmic side of plasma membrane; early endosome; endomembrane system; endoplasmic reticulum membrane; endosome; Golgi cisterna membrane; Golgi membrane; neuron projection; synapse; trans-Golgi network; vesicle membrane | GDP binding GTP binding GTPase activity | Mus musculus | Acetylation Cell projection Cytoplasmic vesicle Direct protein sequencing Endoplasmic reticulum Endosome Golgi apparatus GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Protein transport Reference proteome Transport | MAAAGGGAAA | MAAAGGGAAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQAQSSGGCCSSG | anterograde axonal transport intracellular protein transport positive regulation of dendrite morphogenesis positive regulation of early endosome to late endosome transport positive regulation of receptor-mediated endocytosis protein stabilization Rab protein signal transduction regulation of axon extension regulation o... |
autophagy cellular response to type II interferon endocytic recycling endosome to lysosome transport Golgi vesicle fusion to target membrane positive regulation of macroautophagy protein catabolic process protein localization to plasma membrane protein secretion Rab protein signal transduction regulation of exocytosis ... | autophagosome; endosome; Golgi membrane; lysosomal membrane; lysosome; phagocytic vesicle; plasma membrane; recycling endosome membrane; secretory granule; synaptic vesicle; trans-Golgi network transport vesicle | GDP binding GTP binding GTPase activity | Mus musculus | Acetylation Autophagy Cytoplasmic vesicle Endosome Golgi apparatus GTP-binding Lipoprotein Lysosome Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MDPSAALHRR | MDPSAALHRRPAGGSLGAVSPALSGGQARRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREISRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDVLRNELSNSILSLQPEPEIPPELPPPRPHVRCC | autophagy cellular response to type II interferon endocytic recycling endosome to lysosome transport Golgi vesicle fusion to target membrane positive regulation of macroautophagy protein catabolic process protein localization to plasma membrane protein secretion Rab protein signal transduction regulation of exocytosis ... |
autophagy cellular response to type II interferon endocytic recycling endosome to lysosome transport Golgi vesicle fusion to target membrane positive regulation of macroautophagy protein catabolic process protein localization to plasma membrane protein secretion Rab protein signal transduction regulation of exocytosis ... | autophagosome; endosome; Golgi membrane; lysosomal membrane; lysosome; phagocytic vesicle; plasma membrane; recycling endosome membrane; secretory granule; synaptic vesicle; trans-Golgi network transport vesicle | GDP binding GTP binding GTPase activity | Rattus norvegicus | Acetylation Autophagy Cytoplasmic vesicle Endosome Golgi apparatus GTP-binding Lipoprotein Lysosome Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MDPSAALHRR | MDPSAALHRRPAGGGLGAVSPALSGGQARRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREISRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDVLRSELSNSILSLQPEPEIPPELPPPRPHVRCC | autophagy cellular response to type II interferon endocytic recycling endosome to lysosome transport Golgi vesicle fusion to target membrane positive regulation of macroautophagy protein catabolic process protein localization to plasma membrane protein secretion Rab protein signal transduction regulation of exocytosis ... |
endocytosis endosome organization intracellular protein transport regulation of vesicle size | actin cytoskeleton; early endosome; endomembrane system; endosome membrane; late endosome; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; ruffle | GDP binding GTP binding GTPase activity | Mus musculus | 3D-structure Cell membrane Cell projection Cytoplasmic vesicle Endocytosis Endosome GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport | MALRELKVCL | MALRELKVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDYADSIHAIFVETSAKNAININELFIEISRRIPSTDANPASGGKGFKLRRQPSEPKRSCC | endocytosis endosome organization intracellular protein transport regulation of vesicle size actin cytoskeleton; early endosome; endomembrane system; endosome membrane; late endosome; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; ruffle GDP binding GTP binding GTPase activity Mus musculus 3D-structu... |
bicellular tight junction assembly cellular response to insulin stimulus cortical actin cytoskeleton organization endocytic recycling endosomal transport endothelial cell chemotaxis establishment of Sertoli cell barrier glucose homeostasis Golgi vesicle fusion to target membrane neuron projection development positive r... | bicellular tight junction; cell-cell junction; cytoplasmic vesicle; cytoplasmic vesicle membrane; endocytic vesicle; endosome; Golgi apparatus; insulin-responsive compartment; lamellipodium; lateral plasma membrane; neuron projection; plasma membrane; recycling endosome; recycling endosome membrane; synaptic vesicle; t... | GTP binding GTPase activity protein kinase A catalytic subunit binding | Rattus norvegicus | Cell junction Cell membrane Cell projection Cytoplasmic vesicle Endosome Golgi apparatus GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Tight junction Transport | MAKAYDHLFK | MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKIRTVEIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQREQAERLAREHRIRFFETSAKSSVNVDEAFSSLARDILLKTGGRRSGNSSKPSSTDLKVSDKKNSNKCSLG | bicellular tight junction assembly cellular response to insulin stimulus cortical actin cytoskeleton organization endocytic recycling endosomal transport endothelial cell chemotaxis establishment of Sertoli cell barrier glucose homeostasis Golgi vesicle fusion to target membrane neuron projection development positive r... |
autophagosome assembly cellular defense response cilium assembly craniofacial suture morphogenesis dorsal/ventral neural tube patterning embryonic digit morphogenesis GTP metabolic process intracellular protein transport negative regulation of protein import into nucleus negative regulation of proteolysis nervous syste... | autophagosome; cell junction; centrosome; cytoplasm; cytosol; endomembrane system; endosome membrane; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane | GTP binding GTPase activity | Mus musculus | 3D-structure Cell membrane Cytoplasm Cytoplasmic vesicle Developmental protein Endosome GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MLEEDMEVAI | MLEEDMEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAISSWREKVVAEVGDIPTALVQNKIDLLDDSCIKNEEAEGLAKRLKLRFYRTSVKEDLNVSEVFKYLAEKHLQKLKQQITEDPEQTHSSSNKIGVFNASVGSHLGQNSSSLNGGDVINLRPNKQRTKRTRNPFSSCSVP | autophagosome assembly cellular defense response cilium assembly craniofacial suture morphogenesis dorsal/ventral neural tube patterning embryonic digit morphogenesis GTP metabolic process intracellular protein transport negative regulation of protein import into nucleus negative regulation of proteolysis nervous syste... |
autophagy intracellular protein transport | autophagosome; cytosol; endomembrane system; membrane; mitochondrion | GTP binding GTPase activity | Mus musculus | Autophagy Cytoplasm GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport | MSGQRVDVKV | MSGQRVDVKVVMLGKEYVGKTSLVERYVHDRFLVGPYQNTIGAAFVAKVMCVGDRTVTLGIWDTAGSERYEAMSRIYYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLEEDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVAAFQVMTEDKGVDLSQKANPYFYSCCHH | autophagy intracellular protein transport autophagosome; cytosol; endomembrane system; membrane; mitochondrion GTP binding GTPase activity Mus musculus Autophagy Cytoplasm GTP-binding Lipoprotein Membrane Nucleotide-binding Prenylation Protein transport Reference proteome Transport MSGQRVDVKV MSGQRVDVKVVMLGKEYVGKTSLVER... |
cilium assembly endocytic recycling establishment of melanosome localization filopodium assembly immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor intracellular protein transport melanosome transport regulation of dendrite development regulation of endocytosis regulation of f... | apical plasma membrane; basolateral plasma membrane; dendrite; endocytic vesicle; endomembrane system; endosome; glutamatergic synapse; melanosome; neuronal cell body; plasma membrane; postsynapse; recycling endosome; recycling endosome membrane | GDP binding GTP binding GTPase activity | Mus musculus | Cell projection Endosome GTP-binding Lipoprotein Membrane Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport | MAQAAGLPQA | MAQAAGLPQASTASGQPYVSKLVLLGSSSVGKTSLALRYMKQDFSNVLPTVGCAFFTKVLDLGSSSLKLEIWDTAGQEKYQSVCHLYFRGANAALLVYDITRKDSFHKAQQWLEDLEKEFQPGEVVVMLVGNKTDLGEEREVTFQEGKEFAESKSLLFMETSAKLNYQVSEIFNTVAQELLQRAGDTGSSRPQEGEAVALNQEPPIRQRQCCAR | cilium assembly endocytic recycling establishment of melanosome localization filopodium assembly immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor intracellular protein transport melanosome transport regulation of dendrite development regulation of endocytosis regulation of f... |
brain development endoplasmic reticulum tubular network organization eye development import into nucleus intracellular protein transport lipid droplet organization | apical plasma membrane; endomembrane system; endoplasmic reticulum membrane; endoplasmic reticulum tubular network; Golgi apparatus; lipid droplet; synapse | GDP binding GTP binding GTPase activity | Mus musculus | Acetylation Cell membrane Developmental protein Endoplasmic reticulum GTP-binding Lipid droplet Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Phosphoprotein Prenylation Protein transport Reference proteome Transport | MDEDVLTTLK | MDEDVLTTLKILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKLAIWDTAGQERFRTLTPSYYRGAQGVILVYDVTRRDTFVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEGLKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREESRGGGACGGYCSVL | brain development endoplasmic reticulum tubular network organization eye development import into nucleus intracellular protein transport lipid droplet organization apical plasma membrane; endomembrane system; endoplasmic reticulum membrane; endoplasmic reticulum tubular network; Golgi apparatus; lipid droplet; synapse ... |
epidermis development keratinization keratinocyte differentiation peptide cross-linking | cornified envelope; cytosol | structural constituent of skin epidermis structural molecule activity | Homo sapiens | Cytoplasm Direct protein sequencing Keratinization Reference proteome Repeat | MNSQQQKQPC | MNSQQQKQPCTPPPQPQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCHPKVPEPCQPKVPEPCQPKVPEPCPSTVTPAPAQQKTKQK | epidermis development keratinization keratinocyte differentiation peptide cross-linking cornified envelope; cytosol structural constituent of skin epidermis structural molecule activity Homo sapiens Cytoplasm Direct protein sequencing Keratinization Reference proteome Repeat MNSQQQKQPC MNSQQQKQPCTPPPQPQQQQVKQPCQPPPQEPC... |
antibacterial humoral response defense response to Gram-positive bacterium host-mediated regulation of intestinal microbiota composition | cornified envelope; cytoplasm; cytosol; extracellular region; secretory granule; transport vesicle | lipid binding | Homo sapiens | Antibiotic Antimicrobial Cytoplasmic vesicle Disulfide bond Lipid-binding Reference proteome Repeat Secreted | MSYQQQQCKQ | MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCPQPCPPQQCQQKYPPVTPSPPCQSKYPPKSK | antibacterial humoral response defense response to Gram-positive bacterium host-mediated regulation of intestinal microbiota composition cornified envelope; cytoplasm; cytosol; extracellular region; secretory granule; transport vesicle lipid binding Homo sapiens Antibiotic Antimicrobial Cytoplasmic vesicle Disulfide bo... |
B cell activation cell adhesion cell surface receptor signaling pathway negative regulation of B cell receptor signaling pathway negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production regulation of B cell proliferation regulation of endocytosis regulation of immune response | cell surface; early endosome; external side of plasma membrane; neuronal cell body membrane; plasma membrane; recycling endosome | carbohydrate binding CD4 receptor binding coreceptor activity protein phosphatase binding sialic acid binding | Mus musculus | Alternative splicing Cell adhesion Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Lectin Membrane Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix | MRVHYLWLLL | MRVHYLWLLLILGHVASARYSSANDWTVDHPQTLFAWEGACIRIPCKYKTPLPKARLDNILLFQNYEFDKATKKFTGTVLYNATKTEKDPESELYLSKQGRVTFLGNRIDNCTLKIHPIRANDSGNLGLRMTAGTERWMEPIHLNVSEKPFQPYIQMPSEIRESQSVTLTCGLNFSCFGYDILLKWFLEDSEITSITSSVTSITSSVTSSIKNVYTESKLTFQPKWTDHGKSVKCQVQHSSKVLSERTVRLDVKYTPKLEIKVNPTEVEKNNSVTMTCRVNSSNPKLRTVAVSWFKDGRPLEDQELEQEQQMSKLILHSV... | B cell activation cell adhesion cell surface receptor signaling pathway negative regulation of B cell receptor signaling pathway negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production regulation of B cell proliferation regulation of endocytosis regulation of immune response c... |
cell adhesion cell-cell adhesion | cell periphery; cleavage furrow; microvillus; plasma membrane; uropod | integrin binding | Mus musculus | 3D-structure Cell adhesion Cell projection Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Repeat Signal Transmembrane Transmembrane helix | MSSFACWSLS | MSSFACWSLSLLILFYSPGSGEKAFEVYIWSEKQIVEATESWKINCSTNCAAPDMGGLETPTNKIMLEEHPQGKWKQFLVSNVSKDTVFFCHFTCSGKQHSESLNIRVYQPPAQVTLKLQPPRVFVGEDFTIECTVSPVQPLERLTLSLLRGRETLKNQTFGGAETVPQEATATFNSTALKKDGLNFSCQAELDLRPHGGYIIRSISEYQILEVYEPMQDNQMVIIIVVVSILLFLFVTSVLLCFIFGQHWHRRRTGTYGVLAAWRRLPRAFRARPV | cell adhesion cell-cell adhesion cell periphery; cleavage furrow; microvillus; plasma membrane; uropod integrin binding Mus musculus 3D-structure Cell adhesion Cell projection Disulfide bond Glycoprotein Immunoglobulin domain Membrane Reference proteome Repeat Signal Transmembrane Transmembrane helix MSSFACWSLS MSSFACW... |
cell redox homeostasis hydrogen peroxide catabolic process response to oxidative stress response to reactive oxygen species | alkyl hydroperoxide reductase complex; cytosol | alkyl hydroperoxide reductase activity FAD binding NAD binding thioredoxin-disulfide reductase (NADP) activity | Escherichia coli | 3D-structure Acetylation Disulfide bond FAD Flavoprotein NAD NADP Oxidoreductase Redox-active center Reference proteome | MLDTNMKTQL | MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIAELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPSKEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQNEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIVGSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIV... | cell redox homeostasis hydrogen peroxide catabolic process response to oxidative stress response to reactive oxygen species alkyl hydroperoxide reductase complex; cytosol alkyl hydroperoxide reductase activity FAD binding NAD binding thioredoxin-disulfide reductase (NADP) activity Escherichia coli 3D-structure Acetylat... |
acute inflammatory response to antigenic stimulus calcium-mediated signaling cell surface receptor signaling pathway cellular defense response chemotaxis immune response interleukin-8-mediated signaling pathway metanephric tubule morphogenesis midbrain development negative regulation of apoptotic process negative regul... | cell surface; external side of plasma membrane; mast cell granule; membrane; microtubule cytoskeleton; mitotic spindle; nucleoplasm; plasma membrane | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine receptor activity chemokine receptor activity G protein-coupled receptor activity interleukin-8 binding interleukin-8 receptor activity | Mus musculus | Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MGEFKVDKFN | MGEFKVDKFNIEDFFSGDLDIFNYSSGMPSILPDAVPCHSENLEINSYAVVVIYVLVTLLSLVGNSLVMLVILYNRSTCSVTDVYLLNLAIADLFFALTLPVWAASKVNGWTFGSTLCKIFSYVKEVTFYSSVLLLACISMDRYLAIVHATSTLIQKRHLVKFVCIAMWLLSVILALPILILRNPVKVNLSTLVCYEDVGNNTSRLRVVLRILPQTFGFLVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLVFLLCWLPYNLVLFTDTLMRTKLIKETCERRDDIDKALNATEILGFLHSCLNPIIYAFIGQKF... | acute inflammatory response to antigenic stimulus calcium-mediated signaling cell surface receptor signaling pathway cellular defense response chemotaxis immune response interleukin-8-mediated signaling pathway metanephric tubule morphogenesis midbrain development negative regulation of apoptotic process negative regul... |
cellular response to glucocorticoid stimulus G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger negative regulation of cell population proliferation neuropeptide signaling pathway positive regulation of cytokinesis regulation of insul... | neuron projection; plasma membrane | neuropeptide binding somatostatin receptor activity | Homo sapiens | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MEPLFPASTP | MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQKVLC... | cellular response to glucocorticoid stimulus G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger negative regulation of cell population proliferation neuropeptide signaling pathway positive regulation of cytokinesis regulation of insul... |
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway chemical synaptic transmission detection of light stimulus involved in visual perception G protein-coupled glutamate receptor signaling pathway locomotory behavior positive regulation of calcium ion import across plasma membrane regulat... | dendrite; endoplasmic reticulum membrane; Golgi membrane; new growing cell tip; plasma membrane | adenylate cyclase inhibiting G protein-coupled glutamate receptor activity glutamate receptor activity protein homodimerization activity | Rattus norvegicus | Cell membrane Cell projection Disulfide bond Endoplasmic reticulum G-protein coupled receptor Glycoprotein Golgi apparatus Membrane Receptor Reference proteome Sensory transduction Signal Transducer Transmembrane Transmembrane helix Vision | MGRLPVLLLW | MGRLPVLLLWLAWWLSQAGIACGAGSVRLAGGLTLGGLFPVHARGAAGRACGALKKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEASVRCPGGVPPLRSAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQSIKIPREPKPGEFHKVIRRLMETPNARGIIIFANEDDIRRVLEATRQANLTGHFLWVGSDSWGSKISPILNLEEEAVGA... | adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway chemical synaptic transmission detection of light stimulus involved in visual perception G protein-coupled glutamate receptor signaling pathway locomotory behavior positive regulation of calcium ion import across plasma membrane regulat... |
adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development cGMP-mediated signaling chemotaxis | plasma membrane | adenylate cyclase regulator activity cAMP binding cAMP receptor activity G protein-coupled receptor activity GTPase regulator activity | Dictyostelium discoideum | G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MENLNTTSTA | MENLNTTSTAALTGMTKQENDASYAVLLIADFTSIIGCTLVLLGFWRLKLLRNHITKIITFFCSTSLAKDLISTILTLIEKKQSNGSFQCYLYATVITYGSLACWLWTLCLSFSIYNLIVKREPEPEKFEKYYHVFCWVVPFIMSVIMLSKGVIEVTGNWCWIGNTYVGYRFGLFYGPFLAIWFLAAVLVGLTSRYTYKVIRSSVSDNKDRHMTYQFKLINYIIVFLLCWVFAVINRIVNGLNMFPAWVSILHTYLSVSHGFYASVTFIYNNPLMWRYLASIILIPFTKFGYFVETQQRLEKNKNNNNHSPVGLSNNAQN... | adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development cGMP-mediated signaling chemotaxis plasma membrane adenylate cyclase regulator activity cAMP binding cAMP receptor activit... |
absorption of visible light cellular response to light stimulus detection of light stimulus G protein-coupled receptor signaling pathway phototransduction rhodopsin mediated signaling pathway visual perception | membrane; photoreceptor disc membrane; photoreceptor outer segment; plasma membrane | 11-cis retinal binding G protein-coupled photoreceptor activity photoreceptor activity retinal binding | Danio rerio | Cell projection Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MNGTEGPAFY | MNGTEGPAFYVPMSNATGVVRSPYEYPQYYLVAPWAYGLLAAYMFFLIITGFPVNFLTLYVTIEHKKLRTPLNYILLNLAIADLFMVFGGFTTTMYTSLHGYFVFGRLGCNLEGFFATLGGEMGLWSLVVLAIERWMVVCKPVSNFRFGENHAIMGVAFTWVMACSCAVPPLVGWSRYIPEGMQCSCGVDYYTRTPGVNNESFVIYMFIVHFFIPLIVIFFCYGRLVCTVKEAAAQQQESETTQRAEREVTRMVIIMVIAFLICWLPYAGVAWYIFTHQGSEFGPVFMTLPAFFAKTSAVYNPCIYICMNKQFRHCMITT... | absorption of visible light cellular response to light stimulus detection of light stimulus G protein-coupled receptor signaling pathway phototransduction rhodopsin mediated signaling pathway visual perception membrane; photoreceptor disc membrane; photoreceptor outer segment; plasma membrane 11-cis retinal binding G p... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger hippocampus development response to estradiol | dendrite; perikaryon; postsynaptic specialization membrane | G protein-coupled serotonin receptor activity neurotransmitter receptor activity serotonin binding | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDLPINLTSF | MDLPINLTSFSLSTPSTLEPNRSLDTEALRTSQSFLSAFRVLVLTLLGFLAAATFTWNLLVLATILRVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMILLTWALSAVISLAPLLFGWGETYSELSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRMGSRKTNSVSPIPEAVEVKDASQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDIPALWK... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting serotonin receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger hippocampus development response to estradiol dendrite; p... |
cellular response to histamine chemical synaptic transmission G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger inflammatory response memory phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation ... | cytosol; dendrite; plasma membrane; synapse | G protein-coupled serotonin receptor activity histamine receptor activity neurotransmitter receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSLPNSSCLL | MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRD... | cellular response to histamine chemical synaptic transmission G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger inflammatory response memory phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation ... |
adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell-cell signaling G protein-coupled receptor signaling pathway intracellular signal transduction neuron-glial cell signaling phospholipase C-activating G protein-coupled recepto... | caveola; cytoplasm; nuclear membrane; nucleus; plasma membrane | alpha1-adrenergic receptor activity protein heterodimerization activity | Homo sapiens | Cell membrane Cytoplasm Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Nucleus Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MNPDLDTGHN | MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLF... | adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cell-cell signaling G protein-coupled receptor signaling pathway intracellular signal transduction neuron-glial cell signaling phospholipase C-activating G protein-coupled recepto... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling conditioned place preference eating behavior estrous cycle negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of blood pressure negative regulation of cA... | cytoplasmic vesicle; neuron projection; plasma membrane; synaptic membrane | G protein-coupled receptor activity neuropeptide binding nociceptin receptor activity | Rattus norvegicus | Behavior Cell membrane Cytoplasmic vesicle Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MESLFPAPYW | MESLFPAPYWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRFCTALGYVNSCLNPILYAFLD... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling conditioned place preference eating behavior estrous cycle negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of blood pressure negative regulation of cA... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway behavioral response to ethanol G protein-coupled opioid receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger negative regulation of cAMP-mediated signaling negative r... | axon; dendrite; endoplasmic reticulum; endosome; Golgi apparatus; neuron projection; perikaryon; plasma membrane; synapse | beta-endorphin receptor activity G protein-coupled receptor activity G-protein alpha-subunit binding G-protein beta-subunit binding morphine receptor activity neuropeptide binding voltage-gated calcium channel activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cell projection Cytoplasm Disulfide bond Endosome G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix Ubl conjugation | MDSSAAPTNA | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSW... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway behavioral response to ethanol G protein-coupled opioid receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger negative regulation of cAMP-mediated signaling negative r... |
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling conditioned place preference eating behavior negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of blood pressure negative regulation of cAMP-mediated si... | cytoplasmic vesicle; neuron projection; plasma membrane; synaptic membrane | G protein-coupled receptor activity neuropeptide binding nociceptin receptor activity | Mus musculus | Alternative splicing Behavior Cell membrane Cytoplasmic vesicle Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MESLFPAPFW | MESLFPAPFWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRFCTALGYVNSCLNPILYAFLD... | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway calcium-mediated signaling conditioned place preference eating behavior negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway negative regulation of blood pressure negative regulation of cAMP-mediated si... |
cellular response to follicle-stimulating hormone stimulus follicle-stimulating hormone signaling pathway G protein-coupled receptor signaling pathway positive regulation of adenylate cyclase activity positive regulation of calcium-mediated signaling positive regulation of ERK1 and ERK2 cascade positive regulation of p... | membrane; plasma membrane; receptor complex | follicle-stimulating hormone receptor activity G protein-coupled receptor activity | Ovis aries | Alternative splicing Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Leucine-rich repeat Membrane Receptor Reference proteome Repeat Signal Sulfation Transducer Transmembrane Transmembrane helix | MALFLVALLA | MALFLVALLAFLSLGSGCHHRLCHCSNGVFLCQDSKVTEMPSDLPRDAVELRFVLTKLRVIPEGAFSGFGDLEKIEISQNDVLEVIEANVFSNLPKLHEIRIEKANNLLYIDPDAFQNLPNLRYLLISNTGIKHLPAVHKIQSLQKVLLDIQDNINIHTVERNSFMGLSFESMIVWLSKNGIQEIHNCAFNGTQLDELNLSDNSNLEELPNDVFQGASGPVILDISRTRIRSLPSYGLENLKKLRAKSTYHLKKLPSLEKFVTLVEASLTYPSHCCAFANWRRQTSDLHPICNKSILRQEVDDMTQARGQRISLAEDDEP... | cellular response to follicle-stimulating hormone stimulus follicle-stimulating hormone signaling pathway G protein-coupled receptor signaling pathway positive regulation of adenylate cyclase activity positive regulation of calcium-mediated signaling positive regulation of ERK1 and ERK2 cascade positive regulation of p... |
blood vessel diameter maintenance establishment of localization in cell G protein-coupled receptor signaling pathway mucus secretion negative regulation of ossification phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of chemokine production positive regulation of cytosolic ca... | apical plasma membrane; basolateral plasma membrane; glutamatergic synapse; plasma membrane; presynaptic active zone membrane | A1 adenosine receptor binding ATP binding G protein-coupled purinergic nucleotide receptor activity G protein-coupled UTP receptor activity | Mus musculus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MAADLEPWNS | MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDA... | blood vessel diameter maintenance establishment of localization in cell G protein-coupled receptor signaling pathway mucus secretion negative regulation of ossification phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of chemokine production positive regulation of cytosolic ca... |
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway adult behavior associative learning axon development behavioral fear response chemical synaptic transmission conditioned taste aversion G protein-coupled glutamate receptor signaling pathway glycosylation learning or memory memory multi... | asymmetric synapse; axon; axon terminus; cell cortex; cell surface; dendrite; dendritic shaft; GABA-ergic synapse; glutamatergic synapse; membrane; neuronal cell body; plasma membrane; postsynaptic membrane; presynapse; presynaptic active zone; presynaptic active zone membrane; presynaptic membrane; protein-containing ... | adenylate cyclase inhibiting G protein-coupled glutamate receptor activity adenylate cyclase inhibitor activity calcium channel regulator activity calcium-dependent protein binding calmodulin binding glutamate binding glutamate receptor activity group III metabotropic glutamate receptor activity identical protein bindi... | Rattus norvegicus | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Sensory transduction Signal Transducer Transmembrane Transmembrane helix | MVQLGKLLRV | MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKI... | adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway adult behavior associative learning axon development behavioral fear response chemical synaptic transmission conditioned taste aversion G protein-coupled glutamate receptor signaling pathway glycosylation learning or memory memory multi... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development chemotaxis MAPK cascade phosphatidylinositol-mediated signaling regulation of actin polymerization or depolymerization regulation of adenylate cyclase-activating G protein-coupled receptor signaling pa... | cell leading edge; cytoplasmic side of plasma membrane; cytosol; leading edge membrane; macropinocytic cup; membrane; phagocytic cup; plasma membrane; pseudopodium | enzyme activator activity phosphatidylinositol-3,4,5-trisphosphate binding phosphatidylinositol-3,4-bisphosphate binding protein kinase regulator activity | Dictyostelium discoideum | Cytoplasm Developmental protein Direct protein sequencing Reference proteome | MGKTERKKEL | MGKTERKKELLELFEYEKIKGDVSYSSIMKKAGGNGKGFLDRYFALHRNYILYYKLGKSSLKPDDKQEPQGYINLMDCNPDDTKEIAPLMFQISHKHRTYIVKAKDESSMKQFLTLLIARIRSLEKIDIDKLGCTVVVLTKVKKFREVLTNPLILPDRVSPEMAEEWVKQMKNYNASFNLADPFIKQVEQISEFCRGEVKEYIDWFGGPEGPRLAMIRCEETVLSNWVEYINKTSSEITTYQDNRFFREDFKDIAVHLKNMTTFIDCYNDYMIHCRKYNNNKPNTKFLEEKQTFKEYIEKFIPKVASCNDVSLNQFYDRS... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway aggregation involved in sorocarp development chemotaxis MAPK cascade phosphatidylinositol-mediated signaling regulation of actin polymerization or depolymerization regulation of adenylate cyclase-activating G protein-coupled receptor signaling pa... |
adenylate cyclase-inhibiting serotonin receptor signaling pathway behavior bone remodeling cellular response to alkaloid cellular response to xenobiotic stimulus chemical synaptic transmission negative regulation of serotonin secretion regulation of behavior vasoconstriction | plasma membrane; synapse | G protein-coupled serotonin receptor activity | Didelphis virginiana | Behavior Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Transducer Transmembrane Transmembrane helix | MEQPSRLCSP | MEQPSRLCSPPASGSLTSSQTNHSTFPNPNCSAPDLEPYQDSIALPWKVLLATFLGLITLGTTLSNAFVIATVSRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAGMIIMVWVFSVSISMPPLFWRQAKAEEVADCSVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSSSSGTSINSRAPEGPSESGSPVYVNQVKVKVSDALLEKKKLMAARERKATRTLGIILGA... | adenylate cyclase-inhibiting serotonin receptor signaling pathway behavior bone remodeling cellular response to alkaloid cellular response to xenobiotic stimulus chemical synaptic transmission negative regulation of serotonin secretion regulation of behavior vasoconstriction plasma membrane; synapse G protein-coupled s... |
acute inflammatory response to antigenic stimulus calcium-mediated signaling cell surface receptor signaling pathway cellular defense response chemotaxis immune response interleukin-8-mediated signaling pathway metanephric tubule morphogenesis midbrain development negative regulation of apoptotic process negative regul... | cell surface; external side of plasma membrane; mast cell granule; membrane; mitotic spindle; nucleoplasm | C-C chemokine binding C-C chemokine receptor activity C-X-C chemokine receptor activity chemokine receptor activity G protein-coupled receptor activity interleukin-8 binding interleukin-8 receptor activity | Rattus norvegicus | Cell membrane Chemotaxis Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MGEIRVDNFS | MGEIRVDNFSLEDFFSGDIDSYNYSSDPPFTLSDAAPCPSANLDINRYAVVVIYVLVTLLSLVGNSLVMLVILYNRSTCSVTDVYLLNLAIADLFFALTLPVWAASKVNGWIFGSFLCKVFSFLQEITFYSSVLLLACISMDRYLAIVHATSTLIQKRHLVKFVCITMWFLSLVLSLPIFILRTTVKANPSTVVCYENIGNNTSKWRVVLRILPQTYGFLLPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLVFLLCWLPYNIVLFTDTLMRTKLIKETCERQNEINKALEATEILGFLHSCLNPIIYAFIGQKF... | acute inflammatory response to antigenic stimulus calcium-mediated signaling cell surface receptor signaling pathway cellular defense response chemotaxis immune response interleukin-8-mediated signaling pathway metanephric tubule morphogenesis midbrain development negative regulation of apoptotic process negative regul... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway bone development cellular response to mechanical stimulus cellular response to prostaglandin E stimulus ERK1 and ERK2 cascade immune response inflammatory response JNK casc... | membrane; plasma membrane | prostaglandin E receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MSTPGVNSSA | MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASV... | adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway bone development cellular response to mechanical stimulus cellular response to prostaglandin E stimulus ERK1 and ERK2 cascade immune response inflammatory response JNK casc... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling positive regulation of cold-induced thermogenesis regulation of cytosolic calcium ion concentration regulation of meiotic nuclear division regulation of metabolic process | cytoplasm; plasma membrane | G protein-coupled receptor activity | Mus musculus | Cell membrane G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MMWGAGSSMA | MMWGAGSSMAWFSAGSGSVNVSSVDPVEEPTGPATLLPSPRAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAADFCIGSPEMSLMLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWVGALGLGLVPVLAWNCRDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDADSPRLYTYLTLLPATYNSMINPVIYAFRNQDVQKVLWAICCCCSTSKI... | adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling positive regulation of cold-induced thermogenesis regulation of cytosolic calcium ion concentration regulation of meiotic nuclear division regulation of metabolic process cytoplasm; plasma membrane G... |
adult heart development angiogenesis aorta development apelin receptor signaling pathway atrioventricular valve development blood vessel development coronary vasculature development endocardial cushion formation G protein-coupled receptor signaling pathway gastrulation heart development heart looping negative regulatio... | plasma membrane | apelin receptor activity G protein-coupled receptor activity signaling receptor activity | Homo sapiens | 3D-structure Angiogenesis Cell membrane Developmental protein G-protein coupled receptor Gastrulation Glycoprotein Host-virus interaction Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MEEGGDFDNY | MEEGGDFDNYYGADNQSECEYTDWKSSGALIPAIYMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQAC... | adult heart development angiogenesis aorta development apelin receptor signaling pathway atrioventricular valve development blood vessel development coronary vasculature development endocardial cushion formation G protein-coupled receptor signaling pathway gastrulation heart development heart looping negative regulatio... |
embryonic hemopoiesis hormone biosynthetic process hydrogen peroxide catabolic process response to oxidative stress thyroid hormone generation | cell surface; extracellular space; membrane; mitochondrion | calcium ion binding heme binding iodide peroxidase activity peroxidase activity | Mus musculus | Calcium Disulfide bond EGF-like domain Glycoprotein Heme Hydrogen peroxide Iron Membrane Metal-binding Oxidoreductase Peroxidase Reference proteome Signal Sushi Thyroid hormones biosynthesis Transmembrane Transmembrane helix | MRTLGAMAIM | MRTLGAMAIMLVVMGTVIFLSFILRSRDILCGKTMKSHVISAVETSQLMVDHAVYNTMKRNLKKREVLSPAQLLSFFKLPESTSGAISRAAEIMETSIQVMKREQSQFSTDALSADILGTIANLSGCLPFMLPPRCPDTCLANKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPKGWNPNFLYHGFPLPPVREVTRHLIQVSNEAVTEDDQYSDFLPVWGQYIDHDIALTPQSTSTAAFWGGVDCQLTCENQNPCFPIQLPSNSSGTTACLPFYRSSAACGTGDQGALFGNLSAANPRQQMNGLTSFLDAST... | embryonic hemopoiesis hormone biosynthetic process hydrogen peroxide catabolic process response to oxidative stress thyroid hormone generation cell surface; extracellular space; membrane; mitochondrion calcium ion binding heme binding iodide peroxidase activity peroxidase activity Mus musculus Calcium Disulfide bond EG... |
cellular response to cAMP cellular response to gamma radiation cellular response to type II interferon cellular response to UV-B homeostatic process lung morphogenesis macrophage chemotaxis negative regulation of formation of translation preinitiation complex negative regulation of translation response to lipopolysacch... | cytoplasm; cytosolic large ribosomal subunit; cytosolic ribosome; GAIT complex; ribonucleoprotein complex; ribosome; synapse | mRNA binding structural constituent of ribosome | Rattus norvegicus | Acetylation Citrullination Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein Translation regulation | MAEGQVLVLD | MAEGQVLVLDGRSHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALERLKVLDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLLRLRKQAEKNVEKKICKFTEVLKTNGLLV | cellular response to cAMP cellular response to gamma radiation cellular response to type II interferon cellular response to UV-B homeostatic process lung morphogenesis macrophage chemotaxis negative regulation of formation of translation preinitiation complex negative regulation of translation response to lipopolysacch... |
anterior/posterior pattern specification negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of neurogenesis regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific double-stranded DNA binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Rattus norvegicus | DNA-binding Nucleus Reference proteome Repressor Transcription Transcription regulation | MRLPRGVGDA | MRLPRGVGDAAELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLREQPASVCSTEAPGSLDSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLRQRTVSGGPPSLTPASASAPAPSPPVPPPSSLGLWRPW | anterior/posterior pattern specification negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of neurogenesis regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, R... |
aerobic respiration mitochondrial proton-transporting ATP synthase complex assembly proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis response to resveratrol | mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1); proton-transporting ATP synthase complex; proton-transporting ATP synthase complex, catalytic core F(1) | protein-containing complex binding proton-transporting ATP synthase activity, rotational mechanism | Rattus norvegicus | Acetylation ATP synthesis CF(1) Direct protein sequencing Hydrogen ion transport Ion transport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Transit peptide Transport | MLPAALLRHP | MLPAALLRHPGLRRLVLQARTYAQAAASPAPAAGPGQMSFTFASPTQVFFDGANVRQVDVPTLTGAFGILASHVPTLQVLRPGLVMVHAEDGTTTKYFVSSGSVTVNADSSVQLLAEEVVTLDMLDLGAARANLEKAQSELSGAADEAARAEIQIRIEANEALVKALE | aerobic respiration mitochondrial proton-transporting ATP synthase complex assembly proton motive force-driven ATP synthesis proton motive force-driven mitochondrial ATP synthesis response to resveratrol mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transport... |
behavioral response to pain endothelial cell-cell adhesion myoblast migration negative regulation of angiogenesis positive regulation of cell division positive regulation of endothelial cell proliferation positive regulation of neutrophil chemotaxis positive regulation of peptidyl-tyrosine phosphorylation regulation of... | basement membrane; collagen-containing extracellular matrix; endoplasmic reticulum; extracellular exosome; extracellular region; extracellular space; sarcoplasmic reticulum | calcium ion binding growth factor activity heparin binding integrin binding | Homo sapiens | Calcium Cell adhesion Disulfide bond EGF-like domain Endoplasmic reticulum Extracellular matrix Glycoprotein Growth factor Mitogen Reference proteome Repeat Sarcoplasmic reticulum Secreted Signal Tissue remodeling Unfolded protein response | MLAPRGAAVL | MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYVISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGN... | behavioral response to pain endothelial cell-cell adhesion myoblast migration negative regulation of angiogenesis positive regulation of cell division positive regulation of endothelial cell proliferation positive regulation of neutrophil chemotaxis positive regulation of peptidyl-tyrosine phosphorylation regulation of... |
apoptotic process artery morphogenesis blood coagulation BMP signaling pathway bone growth bone mineralization bone morphogenesis cartilage development cartilage homeostasis cellular senescence chondrocyte development chondrocyte proliferation collagen fibril organization endochondral bone growth growth plate cartilage... | collagen-containing extracellular matrix; extracellular region; extracellular space; protein-containing complex | BMP binding calcium ion binding collagen binding extracellular matrix structural constituent fibronectin binding heparan sulfate proteoglycan binding heparin binding integrin binding protease binding proteoglycan binding vitamin D binding | Rattus norvegicus | 3D-structure Apoptosis Calcium Cell adhesion Disulfide bond EGF-like domain Extracellular matrix Glycoprotein Heparin-binding Phosphoprotein Reference proteome Repeat Secreted Signal | MSPTACVLVL | MSPTACVLVLALAALRATGQGQIPLGGDLAPQMLRELQETNAALQDVRELLRHRVKEITFLKNTVMECDACGMQPARTPGLSVRPVALCAPGSCFPGVVCTETATGARCGPCPPGYTGNGSHCTDVNECNAHPCFPRVRCINTSPGFHCEACPPGFSGPTHEGVGLTFAKTNKQVCTDINECETGQHNCVPNSVCVNTRGSFQCGPCQPGFVGDQRSGCQRRGQHFCPDGSPSPCHEKADCILERDGSRSCVCAVGWAGNGLLCGRDTDLDGFPDEKLRCSERQCRKDNCVTVPNSGQEDVDRDRIGDACDPDADGDGVP... | apoptotic process artery morphogenesis blood coagulation BMP signaling pathway bone growth bone mineralization bone morphogenesis cartilage development cartilage homeostasis cellular senescence chondrocyte development chondrocyte proliferation collagen fibril organization endochondral bone growth growth plate cartilage... |
apoptotic process artery morphogenesis BMP signaling pathway bone mineralization cartilage homeostasis cellular senescence chondrocyte development chondrocyte proliferation collagen fibril organization growth plate cartilage development limb development multicellular organism growth musculoskeletal movement negative re... | collagen-containing extracellular matrix; extracellular region; extracellular space; protein-containing complex | BMP binding calcium ion binding collagen binding heparan sulfate proteoglycan binding heparin binding integrin binding protease binding | Bos taurus | Apoptosis Calcium Cell adhesion Disulfide bond EGF-like domain Extracellular matrix Glycoprotein Heparin-binding Reference proteome Repeat Secreted Signal | MVLAAARVLL | MVLAAARVLLLTLAALGASGQGQMPLGGDLGPQMLRELQETNAALQDVRDLLRQQVKEITFLKNTVMECDACGMQPARTPKLTVRPLSQCSPGFCFPGVACTETANGARCGPCPEGFTGNGSHCADVNECTAHPCFPRVRCINTSPGFRCEACPPGFSGPTHEGVGLAFAKANKQVCTDINECETGQHNCVPNSVCVNTVGSFQCGPCQPGFVGDQASGCRRRPQRFCPDGTPSPCHEKADCVLERDGSRSCVCAVGWAGNGLICGRDTDLDGFPDEKLRCSERQCRKDNCVTVPNSGQEDVDQDGIGDACDPDADGDGV... | apoptotic process artery morphogenesis BMP signaling pathway bone mineralization cartilage homeostasis cellular senescence chondrocyte development chondrocyte proliferation collagen fibril organization growth plate cartilage development limb development multicellular organism growth musculoskeletal movement negative re... |
cell adhesion negative regulation of amyloid-beta formation positive regulation of amyloid precursor protein catabolic process positive regulation of protein processing protein processing | extracellular matrix; extracellular region | LBD domain binding metal ion binding | Rattus norvegicus | 3D-structure Cell adhesion Disulfide bond Extracellular matrix Glycoprotein Metal-binding Reference proteome Repeat Secreted Signal | MRLSPAPLRL | MRLSPAPLRLSRGPALLALALPLAAALAFSDETLDKVAKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGSSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDPTLDGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPSWQPVNVRAAPSAEFSVDRTRHLMSFLTMM... | cell adhesion negative regulation of amyloid-beta formation positive regulation of amyloid precursor protein catabolic process positive regulation of protein processing protein processing extracellular matrix; extracellular region LBD domain binding metal ion binding Rattus norvegicus 3D-structure Cell adhesion Disulfi... |
embryonic digit morphogenesis pattern specification process skeletal system development | chromatin; nucleus; transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific double-stranded DNA binding | Homo sapiens | Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MCERSLYRAG | MCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRVVLREQALALY | embryonic digit morphogenesis pattern specification process skeletal system development chromatin; nucleus; transcription regulator complex DNA-binding transcription factor activity, RNA polymerase II-specific sequence-specific double-stranded DNA binding Homo sapiens Alternative splicing Developmental protein DNA-bind... |
anterior/posterior pattern specification branch elongation of an epithelium embryonic digit morphogenesis embryonic hindgut morphogenesis male genitalia development morphogenesis of an epithelial fold positive regulation of transcription by RNA polymerase II prostate epithelial cord arborization involved in prostate gl... | chromatin; nucleoplasm | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded D... | Homo sapiens | Developmental protein Disease variant DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation Triplet repeat expansion | MSRAGSWDMD | MSRAGSWDMDGLRADGGGAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYPGTSERTGSSSSSSSSAVVAARPEAPPAKECPAPTPAAAAAAPPSAPALGYGYHFGNGYYSCRMSHGVGLQQNALKSSPHASLGGFPVEKYMDVSGLASSSVPANEVPARAKEVSFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPGDVALNQPDMCVYRRGRKKRVPYTKLQLKELENEYAINKFINKDKRRRISAATNLSERQV... | anterior/posterior pattern specification branch elongation of an epithelium embryonic digit morphogenesis embryonic hindgut morphogenesis male genitalia development morphogenesis of an epithelial fold positive regulation of transcription by RNA polymerase II prostate epithelial cord arborization involved in prostate gl... |
epithelial cell differentiation involved in prostate gland development mesenchymal cell differentiation negative regulation of apoptotic process negative regulation of intrinsic apoptotic signaling pathway positive regulation of epidermal growth factor receptor signaling pathway positive regulation of homotypic cell-ce... | cell surface; external side of plasma membrane; extracellular region; plasma membrane; protein complex involved in cell-matrix adhesion; serine-type endopeptidase complex | enzyme binding protein domain specific binding signaling receptor binding | Mus musculus | 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein GPI-anchor Lipoprotein Membrane Receptor Reference proteome Repeat Secreted Signal | MGLPRRLLLL | MGLPRRLLLLLLLATTCVPASQGLQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPRPGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSLKDEDYTRGCGSLPGCPGTAGFHSNQTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCATASWCQGSHVADSFPTHLNVSVSCCHGSGCNSPTGGAPRPGPAQLSLIASLLLTLGL... | epithelial cell differentiation involved in prostate gland development mesenchymal cell differentiation negative regulation of apoptotic process negative regulation of intrinsic apoptotic signaling pathway positive regulation of epidermal growth factor receptor signaling pathway positive regulation of homotypic cell-ce... |
negative regulation of transcription by RNA polymerase II positive regulation of sprouting angiogenesis regulation of heart contraction | A band; cytoplasm; I band; M band; mitochondrion; nucleus; sarcoplasmic reticulum; Z disc | ATPase binding calcium ion binding calcium-dependent protein binding identical protein binding protein homodimerization activity S100 protein binding | Rattus norvegicus | 3D-structure Calcium Cytoplasm Metal-binding Mitochondrion Reference proteome Repeat S-nitrosylation Sarcoplasmic reticulum | MGSELETAME | MGSELETAMETLINVFHAHSGKEGDKYKLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVAALTVACNNFFWENS | negative regulation of transcription by RNA polymerase II positive regulation of sprouting angiogenesis regulation of heart contraction A band; cytoplasm; I band; M band; mitochondrion; nucleus; sarcoplasmic reticulum; Z disc ATPase binding calcium ion binding calcium-dependent protein binding identical protein binding... |
dermatan sulfate catabolic process disaccharide metabolic process glycosaminoglycan catabolic process heparan sulfate proteoglycan catabolic process heparin catabolic process | extracellular exosome; lysosomal lumen | L-iduronidase activity signaling receptor binding | Homo sapiens | 3D-structure Alternative splicing Disease variant Disulfide bond Glycoprotein Glycosidase Hydrolase Lysosome Mucopolysaccharidosis Reference proteome Signal | MRPLRPRAAL | MRPLRPRAALLALLASLLAAPPVAPAEAPHLVHVDAARALWPLRRFWRSTGFCPPLPHSQADQYVLSWDQQLNLAYVGAVPHRGIKQVRTHWLLELVTTRGSTGRGLSYNFTHLDGYLDLLRENQLLPGFELMGSASGHFTDFEDKQQVFEWKDLVSSLARRYIGRYGLAHVSKWNFETWNEPDHHDFDNVSMTMQGFLNYYDACSEGLRAASPALRLGGPGDSFHTPPRSPLSWGLLRHCHDGTNFFTGEAGVRLDYISLHRKGARSSISILEQEKVVAQQIRQLFPKFADTPIYNDEADPLVGWSLPQPWRADVTYAA... | dermatan sulfate catabolic process disaccharide metabolic process glycosaminoglycan catabolic process heparan sulfate proteoglycan catabolic process heparin catabolic process extracellular exosome; lysosomal lumen L-iduronidase activity signaling receptor binding Homo sapiens 3D-structure Alternative splicing Disease v... |
protein secretion by the type II secretion system protein transport by the Sec complex | extracellular region; periplasmic space | alkaline phosphatase activity | Pseudomonas aeruginosa | Direct protein sequencing Hydrolase Periplasm Reference proteome Secreted Signal | MFKRSLIAAS | MFKRSLIAASLSVAALVSAQAMAVTGGGASLPAELYKGSADSILPANFSYAVTGSGTGKNAFLTNNSSLFGTTGTVHYAGSDSVLSGSELTTYNSNYNGTYGPLIQIPSVATSVTVPYRKDGNTTLNLTSAQLCDAFSGAKTTWGQLLGTTDSTPIRIVYRTGSSGTTELFTRHLNSICPTRFATNSTFTNARLPAGGTLPSNWVGVAATSTVVSTVKATNGSLGYVSPDAVNINSNAEVSRVNGNLPTQANVSTALGSVAPPANAADRADPSKWVPVFTNPSAGYSIVGYTNFVFGQCYKDASVSTDVRAFINKHYGGT... | protein secretion by the type II secretion system protein transport by the Sec complex extracellular region; periplasmic space alkaline phosphatase activity Pseudomonas aeruginosa Direct protein sequencing Hydrolase Periplasm Reference proteome Secreted Signal MFKRSLIAAS MFKRSLIAASLSVAALVSAQAMAVTGGGASLPAELYKGSADSILPANF... |
dephosphorylation protein secretion by the type II secretion system protein transport by the Sec complex | extracellular region; periplasmic space | alkaline phosphatase activity metal ion binding | Pseudomonas aeruginosa | Direct protein sequencing Hydrolase Magnesium Metal-binding Periplasm Phosphoprotein Reference proteome Secreted Signal Zinc | MTPGYPLALS | MTPGYPLALSLAVSMAVLGSALPAQARQDDPSLFNRQARGELSEYGGARRVEQDLTQALKQSLSKKKAKNVILLIGDGMGDSEITVARNYARGAGGYFKGIDALPLTGQYTHYSLHKDSGLPDYVTDSAASATAWSTGVKSYNGAIGVDIHEQPHRNLLELAKLNGKATGNVSTAELQDATPAALLAHVTARKCYGPEATSKQCPSNALENGGAGSITEQWLKTRPDVVLGGGAATFAETAKAGRYAGKTLRAQAEARGYRIVENLDELKAVRRANQKQPLIGLFAPGNMPVRWLGPTATYHGNLNQPAVSCEANPKRTA... | dephosphorylation protein secretion by the type II secretion system protein transport by the Sec complex extracellular region; periplasmic space alkaline phosphatase activity metal ion binding Pseudomonas aeruginosa Direct protein sequencing Hydrolase Magnesium Metal-binding Periplasm Phosphoprotein Reference proteome ... |
acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle | catalytic complex; mitochondrial pyruvate dehydrogenase complex; mitochondrion; myelin sheath; nucleolus; pyruvate dehydrogenase complex | pyruvate dehydrogenase (acetyl-transferring) activity pyruvate dehydrogenase (NAD+) activity pyruvate dehydrogenase activity | Mus musculus | Acetylation Carbohydrate metabolism Direct protein sequencing Glucose metabolism Mitochondrion Oxidoreductase Phosphoprotein Pyruvate Reference proteome Thiamine pyrophosphate Transit peptide Tricarboxylic acid cycle | MRKMLAAVSR | MRKMLAAVSRVLAGSAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLL... | acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle catalytic complex; mitochondrial pyruvate dehydrogenase complex; mitochondrion; myelin sheath; nucleolus; pyruvate dehydrogenase complex pyruvate dehydrogenase (acetyl-transferring) activity pyruvate dehydrogenase (NAD+) ac... |
bile acid secretion cellular glucuronidation estrogen metabolic process flavonoid glucuronidation negative regulation of cellular glucuronidation negative regulation of fatty acid metabolic process negative regulation of glucuronosyltransferase activity retinoic acid metabolic process vitamin D3 metabolic process xenob... | endoplasmic reticulum; endoplasmic reticulum membrane | enzyme binding glucuronosyltransferase activity protein heterodimerization activity protein homodimerization activity retinoic acid binding | Homo sapiens | Alternative splicing Endoplasmic reticulum Glycoprotein Glycosyltransferase Lipid metabolism Membrane Reference proteome Signal Transferase Transmembrane Transmembrane helix | MATGLQVPLP | MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVVLTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNMSLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQREVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKA... | bile acid secretion cellular glucuronidation estrogen metabolic process flavonoid glucuronidation negative regulation of cellular glucuronidation negative regulation of fatty acid metabolic process negative regulation of glucuronosyltransferase activity retinoic acid metabolic process vitamin D3 metabolic process xenob... |
cellular glucuronidation | endoplasmic reticulum; endoplasmic reticulum membrane | enzyme binding glucuronosyltransferase activity protein heterodimerization activity protein homodimerization activity | Homo sapiens | Alternative splicing Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Reference proteome Signal Transferase Transmembrane Transmembrane helix | MATGLQVPLP | MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVVLTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKA... | cellular glucuronidation endoplasmic reticulum; endoplasmic reticulum membrane enzyme binding glucuronosyltransferase activity protein heterodimerization activity protein homodimerization activity Homo sapiens Alternative splicing Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Reference proteome Signal... |
circadian regulation of gene expression endocytosis Golgi organization microtubule nucleation non-motile cilium assembly peptidyl-serine phosphorylation positive regulation of canonical Wnt signaling pathway positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein ... | centrosome; ciliary basal body; Golgi membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; spindle microtubule | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity tau-protein kinase activity | Bos taurus | ATP-binding Biological rhythms Cell membrane Cytoplasm Cytoskeleton Golgi apparatus Kinase Membrane Methylation Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Wnt signaling pathway | MELRVGNRYR | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRN... | circadian regulation of gene expression endocytosis Golgi organization microtubule nucleation non-motile cilium assembly peptidyl-serine phosphorylation positive regulation of canonical Wnt signaling pathway positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein ... |
cinnamic acid biosynthetic process defense response drought recovery L-phenylalanine catabolic process lignin catabolic process pollen development response to oxidative stress response to UV-B salicylic acid catabolic process | cytoplasm | phenylalanine ammonia-lyase activity | Arabidopsis thaliana | Cytoplasm Lyase Phenylalanine catabolism Phenylpropanoid metabolism Reference proteome | MEINGAHKSN | MEINGAHKSNGGGVDAMLCGGDIKTKNMVINAEDPLNWGAAAEQMKGSHLDEVKRMVAEFRKPVVNLGGETLTIGQVAAISTIGNSVKVELSETARAGVNASSDWVMESMNKGTDSYGVTTGFGATSHRRTKNGVALQKELIRFLNAGIFGSTKETSHTLPHSATRAAMLVRINTLLQGFSGIRFEILEAITSFLNNNITPSLPLRGTITASGDLVPLSYIAGLLTGRPNSKATGPNGEALTAEEAFKLAGISSGFFDLQPKEGLALVNGTAVGSGMASMVLFETNVLSVLAEILSAVFAEVMSGKPEFTDHLTHRLKHH... | cinnamic acid biosynthetic process defense response drought recovery L-phenylalanine catabolic process lignin catabolic process pollen development response to oxidative stress response to UV-B salicylic acid catabolic process cytoplasm phenylalanine ammonia-lyase activity Arabidopsis thaliana Cytoplasm Lyase Phenylalan... |
blood vessel diameter maintenance blood vessel remodeling cartilage development involved in endochondral bone morphogenesis cellular response to hypoxia cerebellum morphogenesis cysteine biosynthetic process cysteine biosynthetic process from serine cysteine biosynthetic process via cystathionine DNA protection endocho... | cytoplasm; cytosol; nucleus | carbon monoxide binding cystathionine beta-synthase activity enzyme binding heme binding identical protein binding metal ion binding modified amino acid binding nitric oxide binding nitrite reductase (NO-forming) activity oxygen binding protein homodimerization activity pyridoxal phosphate binding S-adenosyl-L-methioni... | Homo sapiens | 3D-structure Allosteric enzyme Alternative splicing Amino-acid biosynthesis CBS domain Cysteine biosynthesis Cytoplasm Disease variant Heme Iron Isopeptide bond Lyase Metal-binding Nucleus Phosphoprotein Pyridoxal phosphate Reference proteome Ubl conjugation | MPSETPQAEV | MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIPTVLDRTVV... | blood vessel diameter maintenance blood vessel remodeling cartilage development involved in endochondral bone morphogenesis cellular response to hypoxia cerebellum morphogenesis cysteine biosynthetic process cysteine biosynthetic process from serine cysteine biosynthetic process via cystathionine DNA protection endocho... |
cell volume homeostasis chloride transmembrane transport mRNA cis splicing, via spliceosome potassium ion transmembrane transport spliceosomal snRNP assembly | cytoskeleton; cytosol; membrane; methylosome; nucleus; pICln-Sm protein complex; plasma membrane; protein-containing complex; spliceosomal complex | intracellular calcium activated chloride channel activity lipid binding potassium channel activity small molecule binding splicing factor binding | Canis lupus familiaris | 3D-structure Acetylation Cytoplasm Cytoskeleton mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome | MSFLKSFPPP | MSFLKSFPPPGSAEGLRQQQPETEAVLNGKGLGTGTLYIAESRLSWLDGSGLGFSLEYPTISLHAVSRDLNAYPREHLYVMVNAKFGEESKESVAEEEDSDDDVEPIAEFRFVPSDKSALEAMFTAMCECQALHPDPEDEDSDDYDGEEYDVEAHEQGQGDIPTFYTYEEGLSHLTAEGQATLERLEGMLSQSVSSQYNMAGVRTEDSTRDYEDGMEVDTTPTVAGQFEDADVDH | cell volume homeostasis chloride transmembrane transport mRNA cis splicing, via spliceosome potassium ion transmembrane transport spliceosomal snRNP assembly cytoskeleton; cytosol; membrane; methylosome; nucleus; pICln-Sm protein complex; plasma membrane; protein-containing complex; spliceosomal complex intracellular c... |
chloride transmembrane transport chloride transport muscle contraction neuronal action potential propagation | chloride channel complex; plasma membrane; sarcolemma | protein homodimerization activity voltage-gated chloride channel activity | Homo sapiens | 3D-structure CBS domain Cell membrane Chloride Chloride channel Disease variant Ion channel Ion transport Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport Voltage-gated channel | MEQSRSQQRG | MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLA... | chloride transmembrane transport chloride transport muscle contraction neuronal action potential propagation chloride channel complex; plasma membrane; sarcolemma protein homodimerization activity voltage-gated chloride channel activity Homo sapiens 3D-structure CBS domain Cell membrane Chloride Chloride channel Diseas... |
chloride transmembrane transport chloride transport muscle contraction neuronal action potential propagation | chloride channel complex; plasma membrane; sarcolemma | protein homodimerization activity voltage-gated chloride channel activity | Rattus norvegicus | CBS domain Cell membrane Chloride Chloride channel Ion channel Ion transport Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport Voltage-gated channel | MERSQSQQHG | MERSQSQQHGGEQSWWGTAPQYQYMPFEHCTSYGLPSENGGLQHRPRKDLGPRHNAHPTQIYGHHKEQYSYQAQDRGIPKKTDSSSTVDSLDEDHYSKCQDCVHRLGRVLRRKLGEDWIFLVLLGLLMALVSWCMDYVSAKSLQAYKWTYAQMQPSLPLQYLAWVTFPLILILFSALFCQLISPQAVGSGIPEMKTILRGVVLKEYLTLKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSMFSGVYEQPYYYTDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLA... | chloride transmembrane transport chloride transport muscle contraction neuronal action potential propagation chloride channel complex; plasma membrane; sarcolemma protein homodimerization activity voltage-gated chloride channel activity Rattus norvegicus CBS domain Cell membrane Chloride Chloride channel Ion channel Io... |
acinar cell differentiation cell differentiation involved in salivary gland development chloride transport lung development positive regulation of oligodendrocyte differentiation regulation of aldosterone biosynthetic process retina development in camera-type eye | actin cytoskeleton; chloride channel complex; dendrite; perikaryon; plasma membrane | voltage-gated chloride channel activity | Rattus norvegicus | CBS domain Cell membrane Chloride Chloride channel Ion channel Ion transport Membrane Phosphoprotein Reference proteome Repeat Transmembrane Transmembrane helix Transport Voltage-gated channel | MAAATAAAAT | MAAATAAAATVAGEGMEPRALQYEQTLMYGRYTQELGAFAKEEAARIRLGGPEPWKGSPSARATPELLEYGQSRCARCRICSVRCHKFLVSRVGEDWIFLVLLGLLMALVSWAMDYAIAVCLQAQQWMSRGLNTNILLQYLAWVTYPVVLITFSAGFTQILAPQAVGSGIPEMKTILRGVVLKEYLTLKTFVAKVIGLTCALGSGMPLGKEGPFVHIASMCAALLSKFLSLFGGIYENESRNTEMLAAACAVGVGCCFAAPIGGVLFSIEVTSTFFAVRNYWRGFFAATFSAFIFRVLAVWNRDEETITALFKTRFRLDF... | acinar cell differentiation cell differentiation involved in salivary gland development chloride transport lung development positive regulation of oligodendrocyte differentiation regulation of aldosterone biosynthetic process retina development in camera-type eye actin cytoskeleton; chloride channel complex; dendrite; ... |
chloride transport response to stimulus sensory perception of sound visual perception | apical plasma membrane; cell cortex; centrosome; chloride channel complex; cytoplasmic vesicle; Golgi apparatus; intracellular membrane-bounded organelle; mitochondrion; plasma membrane | chloride channel activity | Bos taurus | Cell membrane Chloride Chloride channel Cytoplasm Cytoskeleton Golgi apparatus Hearing Ion channel Ion transport Membrane Mitochondrion Phosphoprotein Reference proteome Repeat Sensory transduction Transmembrane Transmembrane helix Transport Vision Voltage-gated channel | MNDENYSTTI | MNDENYSTTIYNRVQTERVYEDSDPAENGGPLYDEVHEDVRREDNLYVNELENQEYDSVAVYPVGRQGRTSASLQPETGEYVLPDEPYSKAQDPHPGEPTADEDISLEELLSPTKDHQSDSEEPQASDPEEPQASDPEEPQGPDPEEPQENGNEMEADLPSPSSFTIQNSRAFSTREISPTSYSADDVSEGNESASASPEINLFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPRLAAKHRESNTAGIDIFVKFSAYIKNTKQQSNA... | chloride transport response to stimulus sensory perception of sound visual perception apical plasma membrane; cell cortex; centrosome; chloride channel complex; cytoplasmic vesicle; Golgi apparatus; intracellular membrane-bounded organelle; mitochondrion; plasma membrane chloride channel activity Bos taurus Cell membra... |
epidermis development epithelial cell differentiation intermediate filament organization skin development spermatogenesis | cytoskeleton; cytosol; extracellular exosome; extracellular space; keratin filament; membrane; nucleus | structural constituent of cytoskeleton | Homo sapiens | Coiled coil Direct protein sequencing Disease variant Intermediate filament Keratin Palmoplantar keratoderma Phosphoprotein Reference proteome | MSCRQFSSSY | MSCRQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLT... | epidermis development epithelial cell differentiation intermediate filament organization skin development spermatogenesis cytoskeleton; cytosol; extracellular exosome; extracellular space; keratin filament; membrane; nucleus structural constituent of cytoskeleton Homo sapiens Coiled coil Direct protein sequencing Disea... |
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