Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cell differentiation mRNA transcription by RNA polymerase II negative regulation of RNA polymerase II transcription preinitiation complex assembly negative regulation of transcription by RNA polymerase II positive regulation of thyroid hormone mediated signaling pathway positive regulation of transcription by RNA polym... | cytosol; nucleus; RNA polymerase II transcription regulator complex | nuclear receptor activity protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding TBP-class protein binding thyroid hormone binding zinc ion binding | Gallus gallus | 3D-structure DNA-binding Metal-binding Nucleus Phosphoprotein Proto-oncogene Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MEQKPSTLDP | MEQKPSTLDPLSEPEDTRWLDGKRKRKSSQCLVKSSMSGYIPSYLDKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDGCCVIDKITRNQCQLCRFKKCISVGMAMDLVLDDSKRVAKRKLIEENRERRRKEEMIKSLQHRPSPSAEEWELIHVVTEAHRSTNAQGSHWKQKRKFLPEDIGQSPMASMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLSAFNLDDTEVALLQAV... | cell differentiation mRNA transcription by RNA polymerase II negative regulation of RNA polymerase II transcription preinitiation complex assembly negative regulation of transcription by RNA polymerase II positive regulation of thyroid hormone mediated signaling pathway positive regulation of transcription by RNA polym... |
MAPK cascade negative regulation of apoptotic process phosphorylation positive regulation of peptidyl-serine phosphorylation regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of TOR signaling | cytosol; mitochondrion | ATP binding MAP kinase kinase kinase activity metal ion binding protein serine kinase activity protein serine/threonine kinase activity | Mus musculus | ATP-binding Kinase Metal-binding Nucleotide-binding Phosphoprotein Proto-oncogene Reference proteome Serine/threonine-protein kinase Transferase Zinc Zinc-finger | MEPPRGPPVS | MEPPRGPPVSGAEPSRAVGTVKVYLPNKQRTVVTVREGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSIQDLSGGSRQQEAPSNLSVNELLTPQGPSPFTQQRDQEHFSFPAPANPPLQRIRSTSTPNVHMVSTTAPMDSSLMQFTAQSFSTDAAGRGGDGAPRGSPSPASVSSGRKSPHSKLPSEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFG... | MAPK cascade negative regulation of apoptotic process phosphorylation positive regulation of peptidyl-serine phosphorylation regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of TOR signaling cytosol; mitochondrion ATP binding MAP kinase kinase kinase activity metal ion binding protein ... |
adaptive thermogenesis astrocyte differentiation cell adhesion cellular response to hypoxia learning or memory long-term synaptic potentiation memory negative regulation of skeletal muscle cell differentiation neuron projection extension positive regulation of apoptotic process positive regulation of canonical NF-kappa... | cytoplasm; extracellular region; extracellular space; neuronal cell body; nucleus; perinuclear region of cytoplasm; ruffle | calcium ion binding calcium-dependent protein binding identical protein binding ion binding protein homodimerization activity RAGE receptor binding S100 protein binding signaling receptor binding tau protein binding zinc ion binding | Rattus norvegicus | 3D-structure Acetylation Calcium Cell adhesion Cytoplasm Direct protein sequencing Metal-binding Nucleus Reference proteome Repeat Secreted Zinc | MSELEKAMVA | MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDEDGDGECDFQEFMAFVSMVTTACHEFFEHE | adaptive thermogenesis astrocyte differentiation cell adhesion cellular response to hypoxia learning or memory long-term synaptic potentiation memory negative regulation of skeletal muscle cell differentiation neuron projection extension positive regulation of apoptotic process positive regulation of canonical NF-kappa... |
positive regulation of cell population proliferation proteolysis regulation of macroautophagy | calpain complex; cytosol; extracellular exosome; membrane; plasma membrane | calcium ion binding calcium-dependent cysteine-type endopeptidase activity | Homo sapiens | 3D-structure Acetylation Calcium Cell membrane Cytoplasm Direct protein sequencing Membrane Metal-binding Phosphoprotein Reference proteome Repeat | MFLVNSFLKG | MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS | positive regulation of cell population proliferation proteolysis regulation of macroautophagy calpain complex; cytosol; extracellular exosome; membrane; plasma membrane calcium ion binding calcium-dependent cysteine-type endopeptidase activity Homo sapiens 3D-structure Acetylation Calcium Cell membrane Cytoplasm Direct... |
adaptive thermogenesis brown fat cell differentiation cellular response to cold cellular response to dehydroepiandrosterone cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species diet induced thermogenesis generation of precursor metabolites and energy mitocho... | mitochondrial envelope; mitochondrial inner membrane; mitochondrion | cardiolipin binding GDP binding GTP binding long-chain fatty acid binding oxidative phosphorylation uncoupler activity proton transmembrane transporter activity purine ribonucleotide binding transmembrane transporter activity | Rattus norvegicus | Ion channel Ion transport Membrane Mitochondrion Mitochondrion inner membrane Oxidation Reference proteome Repeat Transmembrane Transmembrane helix Transport | MVSSTTSEVQ | MVSSTTSEVQPTMGVKIFSAGVSACLADIITFPLDTAKVRLQIQGEGQASSTIRYKGVLGTITTLAKTEGLPKLYSGLPAGIQRQISFASLRIGLYDTVQEYFSSGRETPASLGSKISAGLMTGGVAVFIGQPTEVVKVRMQAQSHLHGIKPRYTGTYNAYRVIATTESLSTLWKGTTPNLMRNVIINCTELVTYDLMKGALVNHHILADDVPCHLLSALVAGFCTTLLASPVDVVKTRFINSLPGQYPSVPSCAMTMYTKEGPAAFFKGFAPSFLRLGSWNVIMFVCFEQLKKELMKSRQTVDCTT | adaptive thermogenesis brown fat cell differentiation cellular response to cold cellular response to dehydroepiandrosterone cellular response to fatty acid cellular response to hormone stimulus cellular response to reactive oxygen species diet induced thermogenesis generation of precursor metabolites and energy mitocho... |
lipid catabolic process malate metabolic process | extracellular region; intracellular membrane-bounded organelle; mitochondrion | lipase activity malate dehydrogenase activity triglyceride lipase activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Reference proteome Secreted Signal | MWLLLITSVI | MWLLLITSVISTFGGAHGLFGKLGPGNPEANMNISQMITYWGYPCQEYEVVTEDGYILGVYRIPHGKNNSENIGKRPVVYLQHGLIASATNWIANLPNNSLAFMLADAGYDVWLGNSRGNTWSRKNVYYSPDSVEFWAFSFDEMAKYDLPATINFIVQKTGQEKIHYVGHSQGTTIGFIAFSTNPTLAKKIKTFYALAPVATVKYTQSPLKKISFIPTFLFKLMFGKKMFLPHTYFDDFLGTEVCSREVLDLLCSNTLFIFCGFDKKNLNVSRFDVYLGHNPAGTSVQDFLHWAQLVRSGKFQAFNWGSPSQNMLHYNQK... | lipid catabolic process malate metabolic process extracellular region; intracellular membrane-bounded organelle; mitochondrion lipase activity malate dehydrogenase activity triglyceride lipase activity Rattus norvegicus Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism R... |
lipid catabolic process phosphatidylcholine catabolic process triglyceride catabolic process | extracellular region | 1-acyl-2-lysophosphatidylserine acylhydrolase activity calcium ion binding phosphatidylserine 1-acylhydrolase activity phospholipase A1 activity phospholipase activity triglyceride lipase activity | Staphylococcus hyicus | 3D-structure Calcium Direct protein sequencing Hydrolase Lipid degradation Lipid metabolism Metal-binding Secreted Signal | MKETKHQHTF | MKETKHQHTFSIRKSAYGAASVMVASCIFVIGGGVAEANDSTTQTTTPLEVAQTSQQETHTHQTPVTSLHTATPEHVDDSKEATPLPEKAESPKTEVTVQPSSHTQEVPALHKKTQQQPAYKDKTVPESTIASKSVESNKATENEMSPVEHHASNVEKREDRLETNETTPPSVDREFSHKIINNTHVNPKTDGQTNVNVDTKTIDTVSPKDDRIDTAQPKQVDVPKENTTAQNKFTSQASDKKPTVKAAPEAVQNPENPKNKDPFVFVHGFTGFVGEVAAKGENHWGGTKANLRNHLRKAGYETYEASVSALASNHERAV... | lipid catabolic process phosphatidylcholine catabolic process triglyceride catabolic process extracellular region 1-acyl-2-lysophosphatidylserine acylhydrolase activity calcium ion binding phosphatidylserine 1-acylhydrolase activity phospholipase A1 activity phospholipase activity triglyceride lipase activity Staphyloc... |
aerobic respiration gluconeogenesis malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle | cytoplasm; membrane; mitochondrial matrix; mitochondrion | L-malate dehydrogenase activity malate dehydrogenase (NADP+) activity malate dehydrogenase activity protein homodimerization activity protein self-association | Rattus norvegicus | Acetylation Direct protein sequencing Glycoprotein Mitochondrion NAD Oxidoreductase Phosphoprotein Reference proteome Transit peptide Tricarboxylic acid cycle | MLSALARPVG | MLSALARPVGAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVIECSFVQSKETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMIAEAI... | aerobic respiration gluconeogenesis malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle cytoplasm; membrane; mitochondrial matrix; mitochondrion L-malate dehydrogenase activity malate dehydrogenase (NADP+) activity malate dehydrogenase activity protein homodimerizatio... |
cellular response to extracellular stimulus glucose catabolic process to lactate via pyruvate lactate metabolic process liver development NAD metabolic process positive regulation of apoptotic process pyruvate catabolic process pyruvate metabolic process response to cAMP response to estrogen response to glucose respons... | cytosol; mitochondrion; oxidoreductase complex; sperm fibrous sheath | identical protein binding kinase binding L-lactate dehydrogenase activity lactate dehydrogenase activity NAD binding | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond NAD Oxidoreductase Phosphoprotein Reference proteome Ubl conjugation | MAALKDQLIV | MAALKDQLIVNLLKEEQVPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLKTPKIVSSKDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPQCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGVNVAGVSLKSLNPQLGTDADKEQWKDVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPISTMIKGLYGIKEDVFLSVPCILGQNGISDVVKVTLTPDEEARLKKSA... | cellular response to extracellular stimulus glucose catabolic process to lactate via pyruvate lactate metabolic process liver development NAD metabolic process positive regulation of apoptotic process pyruvate catabolic process pyruvate metabolic process response to cAMP response to estrogen response to glucose respons... |
mitochondrial electron transport, cytochrome c to oxygen mitochondrial electron transport, ubiquinol to cytochrome c oxidative phosphorylation regulation of compound eye retinal cell programmed cell death sperm individualization | cytosol; mitochondrial intermembrane space; mitochondrion; respirasome | cysteine-type endopeptidase activator activity involved in apoptotic process electron transfer activity heme binding metal ion binding | Drosophila melanogaster | Electron transport Heme Iron Metal-binding Mitochondrion Reference proteome Respiratory chain Transport | MGSGDAENGK | MGSGDAENGKKIFVQKCAQCHTYEVGGKHKVGPNLGGVVGRKCGTAAGYKYTDANIKKGVTWTEGNLDEYLKDPKKYIPGTKMVFAGLKKAEERADLIAFLKSNK | mitochondrial electron transport, cytochrome c to oxygen mitochondrial electron transport, ubiquinol to cytochrome c oxidative phosphorylation regulation of compound eye retinal cell programmed cell death sperm individualization cytosol; mitochondrial intermembrane space; mitochondrion; respirasome cysteine-type endope... |
nodulation purine nucleobase catabolic process urate catabolic process | peroxisome | urate oxidase activity | Glycine max | Direct protein sequencing Nodulation Oxidoreductase Peroxisome Purine metabolism Reference proteome | MAQQEVVEGF | MAQQEVVEGFKFEQRHGKERVRVARVWKTRQGQHFIVEWRVGITLFSDCVNSYLRDDNSDIVATDTMKNTVYAKAKECSDILSAEEFAILLAKHFVSFYQKVTGAIVNIVEKPWERVTVDGQPHEHGFKLGSEKHTTEAIVQKSGSLQLTSGIEGLSVLKTTQSGFVNFIRDKYTALPDTRERMVATEVTALWRYSYESLYSLPQKPLYFTEKYQEVKKVLADTFFGPPKGGVYSPSVQNTLYLMAKATLNRFPDIAYVSLKLPNLHFIPVNISNQDGPIVKFEDDVYLPTDEPHGSIQASLSRLWSKL | nodulation purine nucleobase catabolic process urate catabolic process peroxisome urate oxidase activity Glycine max Direct protein sequencing Nodulation Oxidoreductase Peroxisome Purine metabolism Reference proteome MAQQEVVEGF MAQQEVVEGFKFEQRHGKERVRVARVWKTRQGQHFIVEWRVGITLFSDCVNSYLRDDNSDIVATDTMKNTVYAKAKECSDILSAEEFAILL... |
microtubule cytoskeleton organization mitotic cell cycle nuclear division nuclear migration by microtubule mediated pushing forces | astral microtubule; cytoplasm; microtubule; nucleus; spindle | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Schizosaccharomyces pombe | 3D-structure Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREVISVHVG | MREVISVHVGQAGVQIGNACWELYCLEHGIGPDGFPTENSEVHKNNSYLNDGFGTFFSETGQGKFVPRSIYVDLEPNVIDQVRTGPYKDLFHPEQMVTGKEDASNNYARGHYTVGKEMIDSVLERIRRMADNCSGLQGFLVFHSFGGGTGSGLGALLLERLNMEYGKKSNLQFSVYPAPQVSTSVVEPYNSVLTTHATLDNSDCTFMVDNEACYDICRRNLDIERPTYENLNRLIAQVVSSITASLRFAGSLNVDLNEFQTNLVPYPRIHFPLVTYSPIVSAAKAFHESNSVQEITNQCFEPYNQMVKCDPRTGRYMATC... | microtubule cytoskeleton organization mitotic cell cycle nuclear division nuclear migration by microtubule mediated pushing forces astral microtubule; cytoplasm; microtubule; nucleus; spindle GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Schizosaccharomyces pombe 3D-structure ... |
cytoplasmic microtubule organization microtubule cytoskeleton organization mitochondrion distribution mitotic cell cycle mitotic spindle organization nuclear division nuclear migration by microtubule mediated pushing forces | astral microtubule; cytoplasm; cytosol; microtubule; nucleus; spindle; spindle microtubule | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Schizosaccharomyces pombe | Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREIISIHVG | MREIISIHVGQAGTQIGNACWELYCLEHGIQPNGYMNPETASQNSDGGFSTFFSETGQGKYVPRSIYVDLEPNVIDQVRTGPYRDLFHPEQLITGKEDASNNYARGHYTVGKELVDEVTDKIRRIADNCSGLQGFLVFHSFGGGTGSGFGALLLERLAMEYTKKSKLQFSVYPAPQVSTSVVEPYNSVLTTHATLDLADCTFMVDNESCYDICRRNLDIERPSYENLNRLIAQVVSSITASLRFEGSLNVDLAEFQTNLVPYPRIHFPLVTYAPIVSAAKAFHESNSVQEITNQCFEPYNQMVKCDPRAGRYMATCLLYR... | cytoplasmic microtubule organization microtubule cytoskeleton organization mitochondrion distribution mitotic cell cycle mitotic spindle organization nuclear division nuclear migration by microtubule mediated pushing forces astral microtubule; cytoplasm; cytosol; microtubule; nucleus; spindle; spindle microtubule GTP b... |
actin filament capping actin filament organization cardiac muscle contraction cellular response to reactive oxygen species in utero embryonic development muscle contraction muscle filament sliding negative regulation of cell migration negative regulation of vascular associated smooth muscle cell migration negative regu... | actin cytoskeleton; actin filament; bleb; cytoplasm; myofibril; protein-containing complex; ruffle membrane; stress fiber | actin binding actin filament binding cytoskeletal protein binding disordered domain specific binding identical protein binding protein heterodimerization activity protein homodimerization activity | Rattus norvegicus | 3D-structure Acetylation Actin-binding Alternative splicing Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Muscle protein Phosphoprotein Reference proteome | MDAIKKKMQM | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI | actin filament capping actin filament organization cardiac muscle contraction cellular response to reactive oxygen species in utero embryonic development muscle contraction muscle filament sliding negative regulation of cell migration negative regulation of vascular associated smooth muscle cell migration negative regu... |
aspartate biosynthetic process L-phenylalanine biosynthetic process from chorismate via phenylpyruvate leucine biosynthetic process tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate | cytoplasm; cytosol | aromatic-amino-acid:2-oxoglutarate aminotransferase activity identical protein binding L-leucine:2-oxoglutarate aminotransferase activity L-phenylalanine:2-oxoglutarate aminotransferase activity L-tyrosine:2-oxoglutarate aminotransferase activity protein homodimerization activity pyridoxal phosphate binding | Escherichia coli | 3D-structure Amino-acid biosynthesis Aminotransferase Aromatic amino acid biosynthesis Cytoplasm Pyridoxal phosphate Reference proteome Transferase | MFQKVDAYAG | MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLQAVAEAEARLNAQPHGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTLGGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRFNDLLATLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRIL... | aspartate biosynthetic process L-phenylalanine biosynthetic process from chorismate via phenylpyruvate leucine biosynthetic process tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate cytoplasm; cytosol aromatic-amino-acid:2-oxoglutarate aminotransferase activity identical protein binding L-leucin... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway negative regulation of cyclic-nucleotide phosphodiesterase activity phototransduction response to light stimulus visual perception | G protein-coupled receptor complex; heterotrimeric G-protein complex; photoreceptor disc membrane; photoreceptor inner segment; photoreceptor outer segment membrane | acyl binding G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GDP binding GTP binding GTPase activity metal ion binding protein kinase binding | Bos taurus | 3D-structure Cell projection Direct protein sequencing GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Phosphoprotein Reference proteome Sensory transduction Transducer Vision | MGAGASAEEK | MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYNGPNTYEDAGNYIKVQFLELNMRRDVKEIYSHMT... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway negative regulation of cyclic-nucleotide phosphodiesterase activity phototransduction response to light stimulus visual perception G protein-coupled receptor complex; heterotrimeric G-protein complex; photoreceptor disc membrane; photoreceptor in... |
adenylate cyclase-modulating G protein-coupled receptor signaling pathway background adaptation cell morphogenesis cone retinal bipolar cell differentiation detection of chemical stimulus involved in sensory perception of bitter taste detection of light stimulus involved in visual perception dopamine metabolic process ... | heterotrimeric G-protein complex; photoreceptor inner segment; photoreceptor outer segment; photoreceptor outer segment membrane; synapse | G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Bos taurus | 3D-structure Cell projection GTP-binding Lipoprotein Magnesium Metal-binding Myristate Nucleotide-binding Reference proteome Sensory transduction Transducer Vision | MGSGASAEDK | MGSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEYKAIIYGNVLQSILAIIRAMPTLGIDYAEVSCVDNGRQLNNLADSIEEGTMPPELVEVIRKLWKDGGVQACFDRAAEYQLNDSASYYLNQLDRITAPDYLPNEQDVLRSRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYEDAGNYIKSQFLDLNMRKDVKEIY... | adenylate cyclase-modulating G protein-coupled receptor signaling pathway background adaptation cell morphogenesis cone retinal bipolar cell differentiation detection of chemical stimulus involved in sensory perception of bitter taste detection of light stimulus involved in visual perception dopamine metabolic process ... |
aerobic respiration heme biosynthetic process heme transport mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport mitochondrial transport | cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion | ATP:ADP antiporter activity | Saccharomyces cerevisiae | Antiport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MSHTETQTQQ | MSHTETQTQQSHFGVDFLMGGVSAAIAKTGAAPIERVKLLMQNQEEMLKQGSLDTRYKGILDCFKRTATHEGIVSFWRGNTANVLRYFPTQALNFAFKDKIKSLLSYDRERDGYAKWFAGNLFSGGAAGGLSLLFVYSLDYARTRLAADARGSKSTSQRQFNGLLDVYKKTLKTDGLLGLYRGFVPSVLGIIVYRGLYFGLYDSFKPVLLTGALEGSFVASFLLGWVITMGASTASYPLDTVRRRMMMTSGQTIKYDGALDCLRKIVQKEGAYSLFKGCGANIFRGVAAAGVISLYDQLQLIMFGKKFK | aerobic respiration heme biosynthetic process heme transport mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport mitochondrial transport cytosol; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion ATP:ADP antiporter activity Saccharomyces cerevisiae Antiport ... |
carbon fixation leaf development photosynthesis response to ammonium ion response to cytokinin response to nitrate tricarboxylic acid cycle | cytosol | phosphoenolpyruvate carboxylase activity | Zea mays | 3D-structure Allosteric enzyme Carbon dioxide fixation Cytoplasm Direct protein sequencing Lyase Magnesium Phosphoprotein Photosynthesis Reference proteome | MASTKAPGPG | MASTKAPGPGEKHHSIDAQLRQLVPGKVSEDDKLIEYDALLVDRFLNILQDLHGPSLREFVQECYEVSADYEGKGDTTKLGELGAKLTGLAPADAILVASSILHMLNLANLAEEVQIAHRRRNSKLKKGGFADEGSATTESDIEETLKRLVSEVGKSPEEVFEALKNQTVDLVFTAHPTQSARRSLLQKNARIRNCLTQLNAKDITDDDKQELDEALQREIQAAFRTDEIRRAQPTPQAEMRYGMSYIHETVWKGVPKFLRRVDTALKNIGINERLPYNVSLIRFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYI... | carbon fixation leaf development photosynthesis response to ammonium ion response to cytokinin response to nitrate tricarboxylic acid cycle cytosol phosphoenolpyruvate carboxylase activity Zea mays 3D-structure Allosteric enzyme Carbon dioxide fixation Cytoplasm Direct protein sequencing Lyase Magnesium Phosphoprotein ... |
photorespiration reductive pentose-phosphate cycle | chloroplast | magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity | Pisum sativum | 3D-structure Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Monooxygenase Oxidoreductase Photorespiration Photosynthesis Plastid | MSPQTETKAK | MSPQTETKAKVGFKAGVKDYKLTYYTPDYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYEIEPVPGEDNQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPYAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMLKRAVFARELGVPIVMHDYLTGGFTANTTLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRL... | photorespiration reductive pentose-phosphate cycle chloroplast magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity Pisum sativum 3D-structure Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylati... |
cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth | cytoplasm; cytosol; nucleus | metal ion binding zinc ion binding | Homo sapiens | Acetylation Cadmium Copper Metal-binding Metal-thiolate cluster Phosphoprotein Reference proteome Zinc | MDPNCSCATG | MDPNCSCATGGSCTCTGSCKCKECKCTSCKKSCCSCCPMSCAKCAQGCICKGASEKCSCCA | cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth cytoplasm; cytosol; nucleus metal ion binding zinc ion binding Homo sapiens Acetylation Cadmium Copper Metal-binding Metal-thiolate... |
cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth | cytoplasm; nucleus | metal ion binding zinc ion binding | Homo sapiens | Acetylation Alternative splicing Cadmium Copper Direct protein sequencing Metal-binding Metal-thiolate cluster Reference proteome Zinc | MDPNCSCATG | MDPNCSCATGGSCTCAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCVCKGASEKCSCCA | cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth cytoplasm; nucleus metal ion binding zinc ion binding Homo sapiens Acetylation Alternative splicing Cadmium Copper Direct protein s... |
cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth | cytoplasm; nucleus | metal ion binding zinc ion binding | Homo sapiens | Acetylation Cadmium Copper Direct protein sequencing Metal-binding Metal-thiolate cluster Phosphoprotein Reference proteome Zinc | MDPNCSCAAG | MDPNCSCAAGVSCTCAGSCKCKECKCTSCKKSCCSCCPVGCSKCAQGCVCKGASEKCSCCD | cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion detoxification of copper ion intracellular zinc ion homeostasis negative regulation of growth cytoplasm; nucleus metal ion binding zinc ion binding Homo sapiens Acetylation Cadmium Copper Direct protein sequencing Metal-bindi... |
carbohydrate catabolic process carbohydrate metabolic process polysaccharide digestion | extracellular exosome; extracellular region; extracellular space | alpha-amylase activity calcium ion binding chloride ion binding | Homo sapiens | 3D-structure Alternative splicing Calcium Carbohydrate metabolism Chloride Disulfide bond Glycoprotein Glycosidase Hydrolase Metal-binding Pyrrolidone carboxylic acid Reference proteome Secreted Signal | MKFFLLLFTI | MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPSDRALVFVDNHDNQRGH... | carbohydrate catabolic process carbohydrate metabolic process polysaccharide digestion extracellular exosome; extracellular region; extracellular space alpha-amylase activity calcium ion binding chloride ion binding Homo sapiens 3D-structure Alternative splicing Calcium Carbohydrate metabolism Chloride Disulfide bond G... |
mesenchyme migration positive regulation of gene expression | cell body; cytoplasm; cytoskeleton; filopodium; lamellipodium | ATP binding hydrolase activity | Xenopus laevis | Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Muscle protein Nucleotide-binding Oxidation Reference proteome | MCDDEETTAL | MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIQRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEIT... | mesenchyme migration positive regulation of gene expression cell body; cytoplasm; cytoskeleton; filopodium; lamellipodium ATP binding hydrolase activity Xenopus laevis Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Muscle protein Nucleotide-binding Oxidation Reference proteome MCDDEETTAL MCDDEETTA... |
monoatomic cation transport muscle cell cellular homeostasis musculoskeletal movement neuromuscular junction development neuromuscular process neuromuscular synaptic transmission neuron cellular homeostasis neuronal action potential regulation of membrane potential response to nicotine skeletal muscle contraction skele... | acetylcholine-gated channel complex; cell surface; membrane; neuromuscular junction; neuron projection; plasma membrane; postsynaptic specialization membrane; synapse | acetylcholine-gated monoatomic cation-selective channel activity excitatory extracellular ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Mus musculus | 3D-structure Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MELSTVLLLL | MELSTVLLLLGLCSAGLVLGSEHETRLVAKLFEDYSSVVRPVEDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDVVLYNNADGDFAIVKFTKVLLDYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKEARGWKHWVFYSCCPTTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTSLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHH... | monoatomic cation transport muscle cell cellular homeostasis musculoskeletal movement neuromuscular junction development neuromuscular process neuromuscular synaptic transmission neuron cellular homeostasis neuronal action potential regulation of membrane potential response to nicotine skeletal muscle contraction skele... |
acetylcholine receptor signaling pathway behavioral response to nicotine excitatory postsynaptic potential heart development locomotory behavior nervous system development presynaptic modulation of chemical synaptic transmission regulation of acetylcholine secretion, neurotransmission regulation of dendrite morphogenes... | acetylcholine-gated channel complex; cholinergic synapse; dendrite; dopaminergic synapse; endoplasmic reticulum; Golgi apparatus; neuron projection; neuronal cell body; plasma membrane raft; postsynaptic specialization membrane; presynapse; protein-containing complex; synapse | acetylcholine binding acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity heterocyclic compound binding protein-containing complex binding transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | Cell membrane Disulfide bond Endoplasmic reticulum Glycoprotein Golgi apparatus Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport Ubl conjugation | MGVVLLPPPL | MGVVLLPPPLSMLMLVLMLLPAASASEAEHRLFQYLFEDYNEIIRPVANVSHPVIIQFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWKPSDYQGVEFMRVPAEKIWKPDIVLYNNADGDFQVDDKTKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKDYWESGEWAIIKAPGYKHEIKYNCCEEIYQDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVL... | acetylcholine receptor signaling pathway behavioral response to nicotine excitatory postsynaptic potential heart development locomotory behavior nervous system development presynaptic modulation of chemical synaptic transmission regulation of acetylcholine secretion, neurotransmission regulation of dendrite morphogenes... |
behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization signal transduction synaptic transmission, cholinergic | acetylcholine-gated channel complex; neuron projection; postsynaptic membrane; synapse | acetylcholine-gated monoatomic cation-selective channel activity channel activity transmembrane signaling receptor activity | Bos taurus | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MTPGALLLLL | MTPGALLLLLLGVLGAHLAPGARGSEAEGRLREKLFSGYDSTVRPAREVGDRVWVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPEEHEGIDSLRISAESVWLPDVVLLNNNDGNFDVALDINVVVSSDGSMRWQPPGIYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLSPEGQERQEVYIHEGTFIENGQWEIIHKPSRLIQPSVDPRGGGEGRREEVTFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLV... | behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization signal transduction synaptic transmission, cholinergic acetylcholine-gated channel complex; neuron projection; postsynaptic... |
musculoskeletal movement skeletal muscle tissue growth | acetylcholine-gated channel complex; neuromuscular junction; neuron projection; postsynaptic specialization membrane; synapse | acetylcholine binding acetylcholine-gated monoatomic cation-selective channel activity transmembrane signaling receptor activity | Bos taurus | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MEGSVLTLVL | MEGSVLTLVLLAALVVCGSWGLNEEERLIRHLFEEKAYNKELRPAAHKESVEISLALTLSNLISLKEVEETLTTNVWIEQGWTDSRLQWDAEDFGNISVLRLPADMVWLPEIVLENNNDGSFQISYSCNVLIYPSGSVYWLPPAIFRSSCPISVTYFPFDWQNCSLKFSSLKYTTKEITLSLKQAEEDGRSYPVEWIIIDPEGFTENGEWEIVHRPARVNVDPSVPLDSPNRQDVTFYLIIRRKPLFYVINILVPCVLISFMINLVFYLPADCGEKTSMAISVLLAQSVFLLLISKRLPATSMAIPLIGKFLLFGMVLVT... | musculoskeletal movement skeletal muscle tissue growth acetylcholine-gated channel complex; neuromuscular junction; neuron projection; postsynaptic specialization membrane; synapse acetylcholine binding acetylcholine-gated monoatomic cation-selective channel activity transmembrane signaling receptor activity Bos taurus... |
monoatomic cation transport regulation of membrane potential skeletal muscle contraction | acetylcholine-gated channel complex; neuron projection; plasma membrane; postsynaptic membrane; synapse | acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity | Mus musculus | Alternative splicing Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MQGGQRPHLL | MQGGQRPHLLLLLLAVCLGAQSRNQEERLLADLMRNYDPHLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPKDYEGLWILRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFRSSCSISVTYFPFDWQNCSLIFQSQTYSTSEINLQLSQEDGQAIEWIFIDPEAFTENGEWAIRHRPAKMLLDSVAPAEEAGHQKVVFYLLIQRKPLFYVINIIAPCVLISSVAILIYFLPAKAGGQKCTVATNVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLMVVTILIV... | monoatomic cation transport regulation of membrane potential skeletal muscle contraction acetylcholine-gated channel complex; neuron projection; plasma membrane; postsynaptic membrane; synapse acetylcholine-gated monoatomic cation-selective channel activity ligand-gated monoatomic ion channel activity transmembrane sig... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission cognition entrainment of circadian clock G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger phototran... | dendrite; postsynaptic membrane; synapse | G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity | Sus scrofa | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MNTSAPPAVS | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPAKQPPR... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission cognition entrainment of circadian clock G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger phototran... |
canonical glycolysis cellular response to hypoxia cellular response to interleukin-7 ERK1 and ERK2 cascade gluconeogenesis glycolytic process in utero embryonic development negative regulation of cell growth negative regulation of DNA-templated transcription negative regulation of hypoxia-induced intrinsic apoptotic si... | cell cortex; cell surface; cytoplasm; cytosol; growth cone; membrane; membrane raft; nuclear outer membrane; phosphopyruvate hydratase complex; plasma membrane; synaptic membrane | DNA-binding transcription repressor activity, RNA polymerase II-specific enzyme binding GTPase binding heat shock protein binding identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein homodimerization activity protein-containing complex binding RNA binding RNA polymerase II transcri... | Rattus norvegicus | Acetylation Cell membrane Cytoplasm Direct protein sequencing Glycolysis Hydroxylation Isopeptide bond Lyase Magnesium Membrane Metal-binding Phosphoprotein Plasminogen activation Reference proteome Ubl conjugation | MSILKIHARE | MSILKIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSKAVEHINKTIAPALVSKKLNVVEQEKIDQLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKSAIAKAGYTDQVVIGMDVAASEFYRAGKYDLDFKSPDDASRYITPDQLADLYKSFIKDYPVVSIEDPFDQDDWDAWQKFTATAGIQVVGDDL... | canonical glycolysis cellular response to hypoxia cellular response to interleukin-7 ERK1 and ERK2 cascade gluconeogenesis glycolytic process in utero embryonic development negative regulation of cell growth negative regulation of DNA-templated transcription negative regulation of hypoxia-induced intrinsic apoptotic si... |
female pregnancy hematopoietic stem cell proliferation mammary gland development positive regulation of cell population proliferation positive regulation of hematopoietic stem cell proliferation positive regulation of lactation positive regulation of receptor signaling pathway via JAK-STAT response to nutrient levels | endoplasmic reticulum; extracellular space | growth factor activity hormone activity prolactin receptor binding | Mus musculus | Disulfide bond Endoplasmic reticulum Glycoprotein Hormone Reference proteome Secreted Signal | MLPSSIQPCS | MLPSSIQPCSWILLLLLVNSSLLWKNVASFPMCAMRNGRCFMSFEDTFELAGSLSHNISIEVSELFNEFEKHYSNVSGLRDKSPMRCNTSFLPTPENKEQARLTHYAALLKSGAMILDAWESPLDDLVSELSTIKNVPDIIISKATDIKKKINAVRNGVNALMSTMLQNGDEEKKNPAWFLQSDNEDARIHSLYGMISCLDNDFKKVDIYLNVLKCYMLKIDNC | female pregnancy hematopoietic stem cell proliferation mammary gland development positive regulation of cell population proliferation positive regulation of hematopoietic stem cell proliferation positive regulation of lactation positive regulation of receptor signaling pathway via JAK-STAT response to nutrient levels e... |
blood vessel endothelial cell migration female pregnancy mammary gland development negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration placenta blood vessel development placenta development positive regulation of cell population proliferation positive regulation of lactati... | extracellular space | cytokine activity hormone activity prolactin receptor binding | Mus musculus | Disulfide bond Hormone Reference proteome Secreted Signal | MLPSLIQPCS | MLPSLIQPCSSGTLLMLLMSNLFLWEKVSSAPINASEAVLSDLKDLFDNATVLSGEMSKLGVIMRKEFFMNSFSSETFNKIILDLHKSTENITKAFNSCHTVPINVPETVEDVRKTSFEEFLKMVLHMLLAWKEPLKHLVTELSALPECPYRILSKAEAIEAKNKDLLEYIIRIISKVNPAIKENEDYPTWSDLDSLKSADKETQFFALYMFSFCLRIDLETVDFLVNFLKCLLLYDDVCYSEF | blood vessel endothelial cell migration female pregnancy mammary gland development negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration placenta blood vessel development placenta development positive regulation of cell population proliferation positive regulation of lactati... |
angiogenesis glutamine biosynthetic process protein palmitoylation regulation of endothelial cell migration regulation of sprouting angiogenesis | cytosol; endoplasmic reticulum; mitochondrion; plasma membrane | ATP binding glutamine synthetase activity metal ion binding protein-cysteine S-palmitoyltransferase activity | Cricetulus griseus | Acetylation Angiogenesis ATP-binding Cell membrane Cytoplasm Endoplasmic reticulum Ligase Lipoprotein Magnesium Manganese Membrane Metal-binding Microsome Mitochondrion Nucleotide-binding Palmitate Phosphoprotein Transferase Ubl conjugation | MATSASSHLN | MATSASSHLNKGIKQMYMSLPQGEKVQAMYIWVDGTGEGLRCKTRTLDCEPKCVEELPEWNFDGSSTFQSESSNSDMYLSPVAMFRDPFRKEPNKLVFCEVFKYNQKPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLLGTDGHPFGWPSDGFPGPQGLYYCGVGADKAYRRDIMEAHYRACLYAGVKITGTYAEVKHAQWEFQIGPCEGIRMGDHLWVARFILHRVCKDFGVIATFDSKPIPGNWNGAGCHTNFSTKTMREENGLKHIKEAIEKLSKRHRYHIRAYDPKGGLDNARRLTGFHKTSNINDFSAGVADRS... | angiogenesis glutamine biosynthetic process protein palmitoylation regulation of endothelial cell migration regulation of sprouting angiogenesis cytosol; endoplasmic reticulum; mitochondrion; plasma membrane ATP binding glutamine synthetase activity metal ion binding protein-cysteine S-palmitoyltransferase activity Cri... |
photosynthesis, light harvesting | chloroplast; chloroplast thylakoid; chloroplast thylakoid membrane; nucleus; photosystem I; photosystem II; thylakoid | chlorophyll binding metal ion binding mRNA binding protein domain specific binding | Arabidopsis thaliana | 3D-structure Acetylation Chlorophyll Chloroplast Chromophore Direct protein sequencing Magnesium Membrane Metal-binding Phosphoprotein Photosynthesis Photosystem I Photosystem II Plastid Reference proteome Thylakoid Transit peptide Transmembrane Transmembrane helix | MAASTMALSS | MAASTMALSSPAFAGKAVKLSPAASEVLGSGRVTMRKTVAKPKGPSGSPWYGSDRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFARNRELEVIHSRWAMLGALGCVFPELLARNGVKFGEAVWFKAGSQIFSDGGLDYLGNPSLVHAQSILAIWATQVILMGAVEGYRVAGNGPLGEAEDLLYPGGSFDPLGLATDPEAFAELKVKELKNGRLAMFSMFGFFVQAIVTGKGPIENLADHLADPVNNNAWAFATNFVPGK | photosynthesis, light harvesting chloroplast; chloroplast thylakoid; chloroplast thylakoid membrane; nucleus; photosystem I; photosystem II; thylakoid chlorophyll binding metal ion binding mRNA binding protein domain specific binding Arabidopsis thaliana 3D-structure Acetylation Chlorophyll Chloroplast Chromophore Dire... |
cellular response to hypoxia cellular response to interleukin-7 endoplasmic reticulum to Golgi vesicle-mediated transport insulin processing positive regulation of cell adhesion positive regulation of substrate adhesion-dependent cell spreading positive regulation of viral entry into host cell protein folding protein f... | cytoskeleton; cytosol; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; endoplasmic reticulum-Golgi intermediate compartment; external side of plasma membrane; lamellipodium; melanosome; procollagen-proline 4-dioxygenase complex; protein-containing complex | actin binding enzyme binding integrin binding procollagen-proline 4-dioxygenase activity protein disulfide isomerase activity protein heterodimerization activity protein-containing complex binding protein-disulfide reductase activity thiol oxidase activity | Rattus norvegicus | Acetylation Cell membrane Chaperone Direct protein sequencing Disulfide bond Endoplasmic reticulum Isomerase Membrane Phosphoprotein Redox-active center Reference proteome Repeat Signal | MLSRALLCLA | MLSRALLCLALAWAARVGADALEEEDNVLVLKKSNFAEALAAHNYLLVEFYAPWCGHCKALAPEYAKAAAKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLSDTAAAESLVDSSEVTVIGFFKDAGSDSAKQFLLAAEAVDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEITKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYDGKLSNFKKAAEGFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLI... | cellular response to hypoxia cellular response to interleukin-7 endoplasmic reticulum to Golgi vesicle-mediated transport insulin processing positive regulation of cell adhesion positive regulation of substrate adhesion-dependent cell spreading positive regulation of viral entry into host cell protein folding protein f... |
chromatin organization chromosome segregation DNA replication DNA strand elongation involved in DNA replication DNA topological change mitotic chromosome condensation nuclear migration rDNA heterochromatin formation regulation of mitotic recombination regulation of transcription by RNA polymerase II rRNA transcription ... | nucleolus; nucleoplasm; nucleus; replication fork protection complex | DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity | Saccharomyces cerevisiae | 3D-structure DNA-binding Isomerase Nucleus Phosphoprotein Reference proteome Topoisomerase | MTIADASKVN | MTIADASKVNHELSSDDDDDVPLSQTLKKRKVASMNSASLQDEAEPYDSDEAISKISKKKTKKIKTEPVQSSSLPSPPAKKSATSKPKKIKKEDGDVKVKTTKKEEQENEKKKREEEEEEDKKAKEEEEEYKWWEKENEDDTIKWVTLKHNGVIFPPPYQPLPSHIKLYYDGKPVDLPPQAEEVAGFFAALLESDHAKNPVFQKNFFNDFLQVLKESGGPLNGIEIKEFSRCDFTKMFDYFQLQKEQKKQLTSQEKKQIRLEREKFEEDYKFCELDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSK... | chromatin organization chromosome segregation DNA replication DNA strand elongation involved in DNA replication DNA topological change mitotic chromosome condensation nuclear migration rDNA heterochromatin formation regulation of mitotic recombination regulation of transcription by RNA polymerase II rRNA transcription ... |
anterograde axonal protein transport cellular response to vascular endothelial growth factor stimulus chaperone-mediated protein folding intracellular signal transduction negative regulation of apoptotic process negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway negative regulation of... | axon cytoplasm; cornified envelope; cytoplasm; cytoskeleton; cytosol; extracellular exosome; extracellular space; focal adhesion; nucleus; proteasome complex; spindle; Z disc | identical protein binding protein folding chaperone protein homodimerization activity protein kinase binding protein kinase C binding protein kinase C inhibitor activity RNA binding RNA polymerase II-specific DNA-binding transcription factor binding ubiquitin binding unfolded protein binding | Homo sapiens | 3D-structure Acetylation Chaperone Charcot-Marie-Tooth disease Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Host-virus interaction Methylation Neurodegeneration Neuropathy Nucleus Phosphoprotein Reference proteome Stress response | MTERRVPFSL | MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK | anterograde axonal protein transport cellular response to vascular endothelial growth factor stimulus chaperone-mediated protein folding intracellular signal transduction negative regulation of apoptotic process negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway negative regulation of... |
antimicrobial humoral immune response mediated by antimicrobial peptide cAMP-mediated signaling canonical glycolysis cellular response to type II interferon female pregnancy gluconeogenesis glycolytic process microtubule cytoskeleton organization negative regulation of translation negative regulation of vascular associ... | cytoplasm; cytosol; GAIT complex; glutamatergic synapse; lipid droplet; microtubule cytoskeleton; nucleus; plasma membrane; postsynaptic density, intracellular component; ribonucleoprotein complex | aspartic-type endopeptidase inhibitor activity disordered domain specific binding enzyme binding glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity identical protein binding microtubule binding NAD binding NADP binding peptidyl-cysteine S-nitrosylase activity | Rattus norvegicus | Acetylation ADP-ribosylation Apoptosis Cytoplasm Cytoskeleton Direct protein sequencing Glycolysis Immunity Innate immunity Isopeptide bond Methylation NAD Nucleus Oxidoreductase Phosphoprotein Reference proteome S-nitrosylation Transferase Translation regulation Ubl conjugation | MVKVGVNGFG | MVKVGVNGFGRIGRLVTRAAFSCDKVDIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQAAEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSN... | antimicrobial humoral immune response mediated by antimicrobial peptide cAMP-mediated signaling canonical glycolysis cellular response to type II interferon female pregnancy gluconeogenesis glycolytic process microtubule cytoskeleton organization negative regulation of translation negative regulation of vascular associ... |
oxidative demethylation response to cadmium ion response to dexamethasone response to glucocorticoid response to metal ion response to nutrient response to xenobiotic stimulus steroid metabolic process xenobiotic metabolic process | endoplasmic reticulum membrane | aromatase activity demethylase activity heme binding iron ion binding testosterone 6-beta-hydroxylase activity | Rattus norvegicus | Direct protein sequencing Endoplasmic reticulum Heme Iron Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome | MDLLSALTLE | MDLLSALTLETWVLLAVVLVLLYGFGTRTHGLFKKQGIPGPKPLPFFGTVLNYYMGLWKFDVECHKKYGKIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVSVAKDEEWKRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTMKKVFGAYSMDVITSTSFGVNVDSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPKDSIEFFKKFVYRMKETRLDSVQKHRVDFLQLMMNAHNDSKDKESHTALSDMEITAQSIIFIFAGYEPTSSTLSFVLH... | oxidative demethylation response to cadmium ion response to dexamethasone response to glucocorticoid response to metal ion response to nutrient response to xenobiotic stimulus steroid metabolic process xenobiotic metabolic process endoplasmic reticulum membrane aromatase activity demethylase activity heme binding iron ... |
aspartyl-tRNA aminoacylation | aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; cytosol; nucleus | aspartate-tRNA ligase activity ATP binding RNA binding | Saccharomyces cerevisiae | 3D-structure Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome | MSQDENIVKA | MSQDENIVKAVEESAEPAQVILGEDGKPLSKKALKKLQKEQEKQRKKEERALQLEAEREAREKKAAAEDTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEI... | aspartyl-tRNA aminoacylation aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; cytosol; nucleus aspartate-tRNA ligase activity ATP binding RNA binding Saccharomyces cerevisiae 3D-structure Acetylation Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Phosphopro... |
glutamyl-tRNA aminoacylation | cytosol | ATP binding glutamate-tRNA ligase activity tRNA binding zinc ion binding | Escherichia coli | 3D-structure Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Metal-binding Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome Zinc | MKIKTRFAPS | MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSKERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALKAPVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVA... | glutamyl-tRNA aminoacylation cytosol ATP binding glutamate-tRNA ligase activity tRNA binding zinc ion binding Escherichia coli 3D-structure Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Direct protein sequencing Ligase Metal-binding Nucleotide-binding Phosphoprotein Protein biosynthesis Reference proteome Zinc MKIKTR... |
carbohydrate phosphorylation fructose import across plasma membrane fructose metabolic process glucose 6-phosphate metabolic process glucose import glucose metabolic process glycolytic process intracellular glucose homeostasis mannose metabolic process | cytoplasm; cytosol; mitochondrion | ATP binding fructokinase activity glucokinase activity glucose binding hexokinase activity mannokinase activity | Saccharomyces cerevisiae | 3D-structure Allosteric enzyme ATP-binding Direct protein sequencing Glycolysis Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase | MVHLGPKKPQ | MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKGGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLE... | carbohydrate phosphorylation fructose import across plasma membrane fructose metabolic process glucose 6-phosphate metabolic process glucose import glucose metabolic process glycolytic process intracellular glucose homeostasis mannose metabolic process cytoplasm; cytosol; mitochondrion ATP binding fructokinase activity... |
carbohydrate phosphorylation fructose import across plasma membrane fructose metabolic process glucose 6-phosphate metabolic process glucose import glucose metabolic process glycolytic process intracellular glucose homeostasis mannose metabolic process negative regulation of apoptotic signaling pathway regulation of ce... | cytosol; mitochondrial membrane; mitochondrion; nucleus | ATP binding fructokinase activity glucokinase activity glucose binding hexokinase activity mannokinase activity | Saccharomyces cerevisiae | 3D-structure Allosteric enzyme ATP-binding Direct protein sequencing Glycolysis Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase | MVHLGPKKPQ | MVHLGPKKPQARKGSMADVPKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLSKKGGNIPMIPGWVMDFPTGKESGDFLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRTTQNPDELWEFIADSLKAFIDEQFPQGISEPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQITKRNIPIEVVALINDTTGTLVASYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQGKLSDDIPPSAPMAINCEYGSFDNEHVVLPRTKYDITIDEESPRPGQQTFEKMSSGYYLGEILRLALMD... | carbohydrate phosphorylation fructose import across plasma membrane fructose metabolic process glucose 6-phosphate metabolic process glucose import glucose metabolic process glycolytic process intracellular glucose homeostasis mannose metabolic process negative regulation of apoptotic signaling pathway regulation of ce... |
centrosome cycle cold acclimation negative regulation of cell population proliferation pole plasm mRNA localization positive regulation of insulin receptor signaling pathway positive regulation of neuroblast proliferation proteasome assembly regulation of circadian sleep/wake cycle, sleep response to heat RISC complex ... | centrosome; endoplasmic reticulum chaperone complex; perinuclear region of cytoplasm; polytene chromosome interband; protein folding chaperone complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone insulin receptor binding TPR domain binding unfolded protein binding | Drosophila pseudoobscura pseudoobscura | ATP-binding Chaperone Cytoplasm Nucleotide-binding Reference proteome Stress response | MPEEAETFAF | MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLIADRVTVTSKNNDDEQYVWESSAGGSFTVKADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKDDEAKKDMDTDEPKIEDVGEDEDADKKDKDGKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLCVKHFSVEGQL... | centrosome cycle cold acclimation negative regulation of cell population proliferation pole plasm mRNA localization positive regulation of insulin receptor signaling pathway positive regulation of neuroblast proliferation proteasome assembly regulation of circadian sleep/wake cycle, sleep response to heat RISC complex ... |
amino acid transmembrane transport basic amino acid transport L-arginine transmembrane transport transmembrane transport | eisosome; endoplasmic reticulum; endosome membrane; mitochondrion; plasma membrane | amino acid transmembrane transporter activity basic amino acid transmembrane transporter activity L-arginine transmembrane transporter activity | Saccharomyces cerevisiae | Amino-acid transport Cell membrane Endosome Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MTNSKEDADI | MTNSKEDADIEEKHMYNEPVTTLFHDVEASQTHHRRGSIPLKDEKSKELYPLRSFPTRVNGEDTFSMEDGIGDEDEGEVQNAEVKRELKQRHIGMIALGGTIGTGLFIGLSTPLTNAGPVGALISYLFMGSLAYSVTQSLGEMATFIPVTSSFTVFSQRFLSPAFGAANGYMYWFSWAITFALELSVVGQVIQFWTYKVPLAAWISIFWVIITIMNLFPVKYYGEFEFWVASIKVLAIIGFLIYCFCMVCGAGVTGPVGFRYWRNPGAWGPGIISKDKNEGRFLGWVSSLINAAFTFQGTELVGITAGEAANPRKSVPRA... | amino acid transmembrane transport basic amino acid transport L-arginine transmembrane transport transmembrane transport eisosome; endoplasmic reticulum; endosome membrane; mitochondrion; plasma membrane amino acid transmembrane transporter activity basic amino acid transmembrane transporter activity L-arginine transme... |
cartilage development circadian rhythm developmental growth DNA biosynthetic process dTMP biosynthetic process dTTP biosynthetic process intestinal epithelial cell maturation liver regeneration methylation negative regulation of translation response to cytokine response to ethanol response to folic acid response to glu... | cytoplasm; cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrion; nucleus | folic acid binding mRNA regulatory element binding translation repressor activity protein homodimerization activity sequence-specific mRNA binding thymidylate synthase activity | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Disease variant Dyskeratosis congenita Isopeptide bond Membrane Methyltransferase Mitochondrion Mitochondrion inner membrane Nucleotide biosynthesis Nucleus Phosphoprotein Reference proteome Transferase Ubl conjugation | MPVAGSELPR | MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFGMQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDSLGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMCAWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEGYNPHPTIKMEMAV | cartilage development circadian rhythm developmental growth DNA biosynthetic process dTMP biosynthetic process dTTP biosynthetic process intestinal epithelial cell maturation liver regeneration methylation negative regulation of translation response to cytokine response to ethanol response to folic acid response to glu... |
base-excision repair cell division DNA biosynthetic process DNA ligation DNA recombination lagging strand elongation maintenance of DNA trinucleotide repeats mitotic cell cycle nucleotide-excision repair Okazaki fragment processing involved in mitotic DNA replication | mitochondrion; nucleus | ATP binding DNA binding DNA ligase (ATP) activity metal ion binding | Saccharomyces cerevisiae | 3D-structure Acetylation Alternative initiation ATP-binding Cell cycle Cell division DNA damage DNA recombination DNA repair DNA replication Ligase Magnesium Metal-binding Mitochondrion Nucleotide-binding Nucleus Phosphoprotein Reference proteome Transit peptide | MRRLLTGCLL | MRRLLTGCLLSSARPLKSRLPLLMSSSLPSSAGKKPKQATLARFFTSMKNKPTEGTPSPKKSSKHMLEDRMDNVSGEEEYATKKLKQTAVTHTVAAPSSMGSNFSSIPSSAPSSGVADSPQQSQRLVGEVEDALSSNNNDHYSSNIPYSEVCEVFNKIEAISSRLEIIRICSDFFIKIMKQSSKNLIPTTYLFINRLGPDYEAGLELGLGENLLMKTISETCGKSMSQIKLKYKDIGDLGEIAMGARNVQPTMFKPKPLTVGEVFKNLRAIAKTQGKDSQLKKMKLIKRMLTACKGIEAKFLIRSLESKLRIGLAEKTVL... | base-excision repair cell division DNA biosynthetic process DNA ligation DNA recombination lagging strand elongation maintenance of DNA trinucleotide repeats mitotic cell cycle nucleotide-excision repair Okazaki fragment processing involved in mitotic DNA replication mitochondrion; nucleus ATP binding DNA binding DNA l... |
cellular response to heat connective tissue replacement involved in inflammatory response wound healing cytokine-mediated signaling pathway ectopic germ cell programmed cell death extrinsic apoptotic signaling pathway in absence of ligand fever generation immune response intracellular sodium ion homeostasis negative re... | cytosol; extracellular space; nucleus | copper ion binding cytokine activity interleukin-1 receptor binding | Oryctolagus cuniculus | Acetylation Cytokine Cytoplasm Glycoprotein Inflammatory response Mitogen Nucleus Phosphoprotein Pyrogen Reference proteome Secreted | MAKVPDLFED | MAKVPDLFEDLKNCFSENEEYSSAIDHLSLNQKSFYDASYEPLHEDCMNKVVSLSTSETSVSPNLTFQENVVAVTASGKILKKRRLSLNQPITDVDLETNVSDPEEGIIKPRSVPYTFQRNMRYKYLRIIKQEFTLNDALNQSLVRDTSDQYLRAAPLQNLGDAVKFDMGVYMTSEDSILPVTLRISQTPLFVSAQNEDEPVLLKEMPETPRIITDSESDILFFWETQGNKNYFKSAANPQLFIATKPEHLVHMARGLPSMTDFQIS | cellular response to heat connective tissue replacement involved in inflammatory response wound healing cytokine-mediated signaling pathway ectopic germ cell programmed cell death extrinsic apoptotic signaling pathway in absence of ligand fever generation immune response intracellular sodium ion homeostasis negative re... |
carbohydrate metabolic process | extracellular region | alpha-galactosidase activity | Saccharomyces cerevisiae | 3D-structure Disulfide bond Glycoprotein Glycosidase Hydrolase Secreted Signal | MFAFYFLTAC | MFAFYFLTACISLKGVFGVSPSYNGLGLTPQMGWDNWNTFACDVSEQLLLDTADRISDLGLKDMGYKYIILDDCWSSGRDSDGFLVADEQKFPNGMGHVADHLHNNSFLFGMYSSAGEYTCAGYPGSLGREEEDAQFFANNRVDYLKYDNCYNKGQFGTPEISYHRYKAMSDALNKTGRPIFYSLCNWGQDLTFYWGSGIANSWRMSGDVTAEFTRPDSRCPCDGDEYDCKYAGFHCSIMNILNKAAPMGQNAGVGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGANVNNLKASSYSIYSQASVIAINQDSN... | carbohydrate metabolic process extracellular region alpha-galactosidase activity Saccharomyces cerevisiae 3D-structure Disulfide bond Glycoprotein Glycosidase Hydrolase Secreted Signal MFAFYFLTAC MFAFYFLTACISLKGVFGVSPSYNGLGLTPQMGWDNWNTFACDVSEQLLLDTADRISDLGLKDMGYKYIILDDCWSSGRDSDGFLVADEQKFPNGMGHVADHLHNNSFLFGMYSSAGEYTCAGY... |
proteolysis | plasma membrane | aminopeptidase activity identical protein binding metallopeptidase activity zinc ion binding | Escherichia coli | 3D-structure Aminopeptidase Cell inner membrane Cell membrane Direct protein sequencing Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Zinc | MTQQPQAKYR | MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPAANTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKE... | proteolysis plasma membrane aminopeptidase activity identical protein binding metallopeptidase activity zinc ion binding Escherichia coli 3D-structure Aminopeptidase Cell inner membrane Cell membrane Direct protein sequencing Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Zinc MTQQPQAKYR M... |
cardiac left ventricle morphogenesis insulin processing peptide hormone secretion peptide metabolic process protein localization to membrane protein localization to secretory granule protein processing Wnt signaling pathway | extracellular space; Golgi apparatus; secretory granule membrane; transport vesicle membrane | cell adhesion molecule binding metallocarboxypeptidase activity neurexin family protein binding zinc ion binding | Bos taurus | Carboxypeptidase Cleavage on pair of basic residues Cytoplasmic vesicle Direct protein sequencing Glycoprotein Hydrolase Membrane Metal-binding Metalloprotease Protease Reference proteome Secreted Signal Zinc Zymogen | MARRGGCALL | MARRGGCALLVLCGSLAACAWLLGAEARGPGGPVAGARRRRRPQEDGISFEYHRYPELREALVSVWLQCAAVSRIYTVGRSFEGRELLVLELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVQLIHNTRIHIMPSLNPDGFEKAASQLGELKDWFVGRSNAQGIDLNRNFPDLDRIVYINEKEGGPNNHLLKNLKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSCPDDDIFQSLARAYSSFNPPMSDPDRPPCRKNDDDSSFVEGTTNGAAWYS... | cardiac left ventricle morphogenesis insulin processing peptide hormone secretion peptide metabolic process protein localization to membrane protein localization to secretory granule protein processing Wnt signaling pathway extracellular space; Golgi apparatus; secretory granule membrane; transport vesicle membrane cel... |
cellular response to cadmium ion cellular response to ethanol cellular response to L-glutamine defense response electron transport chain hydrogen peroxide biosynthetic process hypoxia-inducible factor-1alpha signaling pathway inflammatory response innate immune response monoatomic ion transmembrane transport positive r... | dendrite; endoplasmic reticulum membrane; monoatomic ion channel complex; NADPH oxidase complex; neuronal cell body; nuclear envelope; perinuclear endoplasmic reticulum; phagocytic vesicle membrane; plasma membrane; specific granule membrane; tertiary granule membrane | flavin adenine dinucleotide binding heme binding metal ion binding protein heterodimerization activity superoxide-generating NAD(P)H oxidase activity | Homo sapiens | 3D-structure Cell membrane Chronic granulomatous disease Direct protein sequencing Disease variant Electron transport FAD Flavoprotein Glycoprotein Heme Ion channel Ion transport Iron Isopeptide bond Membrane Metal-binding NADP Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport... | MGNWAVNEGL | MGNWAVNEGLSIFVILVWLGLNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAACLNFNCMLILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWCVNARVNNSDPYSVALSELGDRQNESYLNFARKRIKNPEGGLYLAVTLLAGITGVVITLCLILIITSSTKTIRRSYFEVFWYTHHLFVIFFIGLAIHGAERIVRGQTAESLAVHNITVCEQKISEWGKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKVVTHPFKTIELQMKKKGFKME... | cellular response to cadmium ion cellular response to ethanol cellular response to L-glutamine defense response electron transport chain hydrogen peroxide biosynthetic process hypoxia-inducible factor-1alpha signaling pathway inflammatory response innate immune response monoatomic ion transmembrane transport positive r... |
methane catabolic process methanol metabolic process | peroxisomal matrix | alcohol oxidase activity flavin adenine dinucleotide binding | Komagataella phaffii | 3D-structure Direct protein sequencing FAD Flavoprotein Methanol utilization Oxidoreductase Peroxisome Reference proteome | MAIPEEFDIL | MAIPEEFDILVLGGGSSGSCIAGRLANLDHSLKVGLIEAGENNLNNPWVYLPGIYPRNMKLDSKTASFYTSNPSPHLNGRRAIVPCANVLGGGSSINFMMYTRGSASDYDDFQAEGWKTKDLLPLMKKTETYQRACNNPDIHGFEGPIKVSFGNYTYPVCQDFLRASESQGIPYVDDLEDLVTAHGAEHWLKWINRDTGRRSDSAHAFVHSTMRNHDNLYLICNTKVDKIIVEDGRAAAVRTVPSKPLNPKKPSHKIYRARKQIVLSCGTISSPLVLQRSGFGDPIKLRAAGVKPLVNLPGVGRNFQDHYCFFSPYRIKP... | methane catabolic process methanol metabolic process peroxisomal matrix alcohol oxidase activity flavin adenine dinucleotide binding Komagataella phaffii 3D-structure Direct protein sequencing FAD Flavoprotein Methanol utilization Oxidoreductase Peroxisome Reference proteome MAIPEEFDIL MAIPEEFDILVLGGGSSGSCIAGRLANLDHS... |
protein N-linked glycosylation protein N-linked glycosylation via asparagine | cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; melanosome; membrane; oligosaccharyltransferase complex; rough endoplasmic reticulum | RNA binding | Homo sapiens | 3D-structure Acetylation Endoplasmic reticulum Glycoprotein Isopeptide bond Membrane Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MEAPAAGLFL | MEAPAAGLFLLLLLGTWAPAPGSASSEAPPLINEDVKRTVDLSSHLAKVTAEVVLAHLGGGSTSRATSFLLALEPELEARLAHLGVQVKGEDEEENNLEVRETKIKGKSGRFFTVKLPVALDPGAKISVIVETVYTHVLHPYPTQITQSEKQFVVFEGNHYFYSPYPTKTQTMRVKLASRNVESYTKLGNPTRSEDLLDYGPFRDVPAYSQDTFKVHYENNSPFLTITSMTRVIEVSHWGNIAVEENVDLKHTGAVLKGPFSRYDYQRQPDSGISSIRSFKTILPAAAQDVYYRDEIGNVSTSHLLILDDSVEMEIRPRF... | protein N-linked glycosylation protein N-linked glycosylation via asparagine cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; melanosome; membrane; oligosaccharyltransferase complex; rough endoplasmic reticulum RNA binding Homo sapiens 3D-structure Acetylation Endoplasmic reticulum Glycoprotein Isopeptid... |
viral budding from plasma membrane viral entry into host cell virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity host cell surface receptor binding identical protein binding | Parainfluenza virus 5 | 3D-structure Disulfide bond Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction Hydrolase Membrane Reference proteome Signal-anchor Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Virion Virus entry into host cell | MVAEDAPVRA | MVAEDAPVRATCRVLFRTTTLIFLCTLLALSISILYESLITQKQIMSQAGSTGSNSGLGSITDLLNNILSVANQIIYNSAVALPLQLDTLESTLLTAIKSLQTSDKLEQNCSWSAALINDNRYINGINQFYFSIAEGRNLTLGPLLNMPSFIPTATTPEGCTRIPSFSLTKTHWCYTHNVILNGCQDHVSSNQFVSMGIIEPTSAGFPFFRTLKTLYLSDGVNRKSCSISTVPGGCMMYCFVSTQPERDDYFSAAPPEQRIIIMYYNDTIVERIINPPGVLDVWATLNPGTGSGVYYLGWVLFPIYGGVIKGTSLWNNQA... | viral budding from plasma membrane viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity host cell surface receptor binding identical prote... |
viral entry into host cell virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity host cell surface receptor binding | Sendai virus ) | Disulfide bond Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction Hydrolase Membrane Signal-anchor Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Virion Virus entry into host cell | MDGDRGKRDS | MDGDRGKRDSYWSTSPSGSTTKPASGWERSSKADTWLLILSFTQWALSIATVIICIIISARQGYSMKEYSMTVEALNMSSREVKESLTSLIRQEVIARAVNIQSSVQTGIPVLLNKNSRDVIQMIDKSCSRQELTQHCESTIAVHHADGIAPLEPHSFWRCPVGEPYLSSDPEISLLPGPSLLSGSTTISGCVRLPSLSIGEAIYAYSSNLITQGCADIGKSYQVLQLGYISLNSDMFPDLNPVVSHTYDINDNRKSCSVVATGTRGYQLCSMPTVDERTDYSSDGIEDLVLDVLDLKGRTKSHRYRNSEVDLDHPFSAL... | viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane exo-alpha-(2->3)-sialidase activity exo-alpha-(2->6)-sialidase activity exo-alpha-(2->8)-sialidase activity host cell surface receptor binding Sendai virus )Disulfide bond Glycoprotein Hemagg... |
DNA-templated transcription negative stranded viral RNA replication | host cell cytoplasm; protein-containing complex | disordered domain specific binding RNA binding RNA-dependent RNA polymerase activity | Sendai virus | 3D-structure Chaperone Coiled coil Host cytoplasm Phosphoprotein RNA editing Viral RNA replication | MDQDAFILKE | MDQDAFILKEDSEVEREAPGGRESLSDVIGFLDAVLSSEPTDIGGDRSWLHNTINTPQGPGSAHRAKSEGEGEVSTPSTQDNRSGEESRVSGRTSKPEAEAHAGNLDKQNIHRAFGGRTGTNSVSQDLGDGGDSGILENPPNERGYPRSGIEDENREMAAHPDKRGEDQAEGLPEEVRGGTSLPDEGEGGASNNGRSMEPGSSHSARVTGVLVIPSPELEEAVLRRNKRRPTNSGSKPLTPATVPGTRSPPLNRYNSTGSPPGKPPSTQDEHINSGDTPAVRVKDRKPPIGTRSVSDCPANGRPIHPGLESDSTKKGIGE... | DNA-templated transcription negative stranded viral RNA replication host cell cytoplasm; protein-containing complex disordered domain specific binding RNA binding RNA-dependent RNA polymerase activity Sendai virus 3D-structure Chaperone Coiled coil Host cytoplasm Phosphoprotein RNA editing Viral RNA replication MDQDAF... |
transport of virus in host, cell to cell | host cell cytoplasm; host cell nucleolus; host cell plasmodesma; host cytoskeleton | ATP binding ATP hydrolysis activity helicase activity RNA binding | Barley stripe mosaic virus | ATP-binding Helicase Host cell junction Host cytoplasm Host cytoskeleton Host nucleus Hydrolase Nucleotide-binding Reference proteome Repeat RNA-binding Transport Viral movement protein | MDMTKTVEEK | MDMTKTVEEKKTNGTDSVKGVFENSTIPKVPTGQEMGGDGSSTSKLKETLKVADQTPLSVDNGAKSKLDSSDRQVPGVADQTPLSVDNGAKSKLDSSDRQVPGPELKPNVKKSKKKRIQKPAQPSGPNDLKGGTKGSSQVGENVSENYTGISKEAAKQKQKTPKSVKMQSNLADKFKANDTRRSELINKFQQFVHETCLKSDFEYTGRQYFRARSNFFEMIKLASLYDKHLKECMARACTLERERLKRKLLLVRALKPAVDFLTGIISGVPGSGKSTIVRTLLKGEFPAVCALANPALMNDYSGIEGVYGLDDLLLSAVP... | transport of virus in host, cell to cell host cell cytoplasm; host cell nucleolus; host cell plasmodesma; host cytoskeleton ATP binding ATP hydrolysis activity helicase activity RNA binding Barley stripe mosaic virus ATP-binding Helicase Host cell junction Host cytoplasm Host cytoskeleton Host nucleus Hydrolase Nucleot... |
adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling positive regulation of GTPase activity sensory perception of chemic... | heterotrimeric G-protein complex | adenylate cyclase activator activity beta-2 adrenergic receptor binding corticotropin-releasing hormone receptor 1 binding D1 dopamine receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity insulin-like growth factor receptor binding ionotropic glutamate receptor binding metal ion bin... | Bos taurus | 3D-structure Alternative splicing Cell membrane GTP-binding Isopeptide bond Lipoprotein Magnesium Membrane Metal-binding Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transducer Ubl conjugation | MGCLGNSKTE | MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTT... | adenylate cyclase-activating adrenergic receptor signaling pathway adenylate cyclase-activating dopamine receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cAMP-mediated signaling positive regulation of GTPase activity sensory perception of chemic... |
lipid metabolic process xenobiotic catabolic process xenobiotic metabolic process | cytosol | glutathione binding glutathione transferase activity | Rattus norvegicus | Cytoplasm Direct protein sequencing Lipid metabolism Reference proteome Transferase | MPGKPVLHYF | MPGKPVLHYFDGRGRMEPIRWLLAAAGVEFEEQFLKTRDDLARLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIATKYNLYGKDMKERALIDMYAEGVADLDEIVLHYPYIPPGEKEASLAKIKDKARNRYFPAFEKVLKSHGQDYLVGNRLSRADVYLVQVLYHVEELDPSALANFPLLKALRTRVSNLPTVKKFLQPGSQRKPLEDEKCVESAVKIFS | lipid metabolic process xenobiotic catabolic process xenobiotic metabolic process cytosol glutathione binding glutathione transferase activity Rattus norvegicus Cytoplasm Direct protein sequencing Lipid metabolism Reference proteome Transferase MPGKPVLHYF MPGKPVLHYFDGRGRMEPIRWLLAAAGVEFEEQFLKTRDDLARLRNDGSLMFQQVPMVEIDGMK... |
cellular detoxification of nitrogen compound cellular response to xenobiotic stimulus glutathione derivative biosynthetic process glutathione metabolic process hepoxilin biosynthetic process nitrobenzene metabolic process prostaglandin metabolic process response to amino acid response to axon injury response to ethanol... | cytoplasm; cytosol; extracellular region; protein-containing complex | enzyme binding glutathione binding glutathione transferase activity identical protein binding nickel cation binding protein homodimerization activity protein kinase binding steroid binding | Rattus norvegicus | 3D-structure Cytoplasm Direct protein sequencing Lipid metabolism Olfaction Phosphoprotein Reference proteome Sensory transduction Transferase | MPMILGYWNV | MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK | cellular detoxification of nitrogen compound cellular response to xenobiotic stimulus glutathione derivative biosynthetic process glutathione metabolic process hepoxilin biosynthetic process nitrobenzene metabolic process prostaglandin metabolic process response to amino acid response to axon injury response to ethanol... |
chromatin organization negative regulation of cell population proliferation protein localization to CENP-A containing chromatin | CENP-A containing nucleosome; extracellular exosome; nucleosome; nucleus | DNA binding protein heterodimerization activity structural constituent of chromatin | Homo sapiens | 3D-structure Acetylation Chromosome Citrullination DNA-binding Hydroxylation Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSGRGKQGGK | MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK | chromatin organization negative regulation of cell population proliferation protein localization to CENP-A containing chromatin CENP-A containing nucleosome; extracellular exosome; nucleosome; nucleus DNA binding protein heterodimerization activity structural constituent of chromatin Homo sapiens 3D-structure Acetylati... |
chromatin remodeling double-strand break repair homologous chromosome segregation mitotic chromosome condensation mitotic DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling | chromosome, subtelomeric region; mating-type region heterochromatin; nucleosome; nucleus; pericentric heterochromatin; rDNA heterochromatin | chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin | Schizosaccharomyces pombe | Acetylation Chromosome DNA damage DNA repair DNA-binding Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome | MSGGKSGGKA | MSGGKSGGKAAVAKSAQSRSAKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVVPNINAHLLPKTSGRTGKPSQEL | chromatin remodeling double-strand break repair homologous chromosome segregation mitotic chromosome condensation mitotic DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling chromosome, subtelomeric region; mating-type region heterochromatin; nucleosome; nucleus; pericentric heterochromatin; rDNA... |
chromatin remodeling double-strand break repair homologous chromosome segregation mitotic chromosome condensation mitotic DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling | chromosome, subtelomeric region; mating-type region heterochromatin; nucleosome; nucleus; pericentric heterochromatin; rDNA heterochromatin | chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin | Schizosaccharomyces pombe | 3D-structure Acetylation Chromosome DNA damage DNA repair DNA-binding Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome | MSGGKSGGKA | MSGGKSGGKAAVAKSAQSRSAKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVVPNINAHLLPKQSGKGKPSQEL | chromatin remodeling double-strand break repair homologous chromosome segregation mitotic chromosome condensation mitotic DNA damage checkpoint signaling mitotic G2 DNA damage checkpoint signaling chromosome, subtelomeric region; mating-type region heterochromatin; nucleosome; nucleus; pericentric heterochromatin; rDNA... |
chromatin organization DNA repair negative regulation of transcription by RNA polymerase II | nucleosome; nucleus; replication fork protection complex | DNA binding protein heterodimerization activity structural constituent of chromatin | Saccharomyces cerevisiae | 3D-structure Acetylation Chromosome DNA damage DNA repair DNA-binding Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSGGKGGKAG | MSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKATKASQEL | chromatin organization DNA repair negative regulation of transcription by RNA polymerase II nucleosome; nucleus; replication fork protection complex DNA binding protein heterodimerization activity structural constituent of chromatin Saccharomyces cerevisiae 3D-structure Acetylation Chromosome DNA damage DNA repair DNA... |
chromatin organization DNA repair | nucleosome; nucleus; replication fork protection complex | DNA binding protein heterodimerization activity structural constituent of chromatin | Saccharomyces cerevisiae | 3D-structure Acetylation Chromosome DNA damage DNA repair DNA-binding Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSGGKGGKAG | MSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKTAKASQEL | chromatin organization DNA repair nucleosome; nucleus; replication fork protection complex DNA binding protein heterodimerization activity structural constituent of chromatin Saccharomyces cerevisiae 3D-structure Acetylation Chromosome DNA damage DNA repair DNA-binding Isopeptide bond Methylation Nucleosome core Nucle... |
chromatin remodeling double-strand break repair via homologous recombination | nucleosome; nucleus; site of double-strand break | chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin | Schizosaccharomyces pombe | Acetylation Chromosome Direct protein sequencing DNA-binding Isopeptide bond Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSAAEKKPAS | MSAAEKKPASKAPAGKAPRDTMKSADKKRGKNRKETYSSYIYKVLKQVHPDTGISNQAMRILNSFVNDIFERIATEASKLAAYNKKSTISSREIQTAVRLILPGELAKHAVTEGTKSVTKYSSSAQ | chromatin remodeling double-strand break repair via homologous recombination nucleosome; nucleus; site of double-strand break chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin Schizosaccharomyces pombe Acetylation Chromosome Direct protein sequencing... |
cardiac muscle tissue development detection of light stimulus involved in visual perception embryonic organ morphogenesis embryonic retina morphogenesis in camera-type eye embryonic skeletal system development eye development female genitalia morphogenesis gluconeogenesis glucose homeostasis heart development heart tra... | extracellular space; protein-containing complex | protein-containing complex binding retinal binding retinol binding retinol transmembrane transporter activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Methylation Reference proteome Retinol-binding Secreted Signal Transport Vitamin A | MEWVWALVLL | MEWVWALVLLAALGGGSAERDCRVSSFRVKENFDKARFSGLWYAIAKKDPEGLFLQDNIIAEFSVDEKGHMSATAKGRVRLLSNWEVCADMVGTFTDTEDPAKFKMKYWGVASFLQRGNDDHWIIDTDYDTFALQYSCRLQNLDGTCADSYSFVFSRDPNGLTPETRRLVRQRQEELCLERQYRWIEHNGYCQSRPSRNSL | cardiac muscle tissue development detection of light stimulus involved in visual perception embryonic organ morphogenesis embryonic retina morphogenesis in camera-type eye embryonic skeletal system development eye development female genitalia morphogenesis gluconeogenesis glucose homeostasis heart development heart tra... |
apoptotic process biomineral tissue development granzyme-mediated programmed cell death signaling pathway maintenance of granzyme B location in T cell secretory granule maintenance of protease location in mast cell secretory granule mast cell secretory granule organization modulation of chemical synaptic transmission n... | cytolytic granule; extracellular space; glutamatergic synapse; Golgi apparatus; mast cell granule; postsynaptic specialization, intracellular component; Schaffer collateral - CA1 synapse; secretory granule; zymogen granule | collagen binding | Rattus norvegicus | Apoptosis Biomineralization Direct protein sequencing Disulfide bond Glycoprotein Golgi apparatus Lysosome Proteoglycan Reference proteome Repeat Secreted Signal | MRQVPVGTRL | MRQVPVGTRLVLALAFVLVWGSSVQGYPARRARYQWVRCKPDGIFANCIEEKGPRFDLIAEESNVGPPMTDPVLMRGFPNDFFPISDDYSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSLADMEWEYQPTDENNIVYFNYGPFDRMLTEQNQEQPGDFII | apoptotic process biomineral tissue development granzyme-mediated programmed cell death signaling pathway maintenance of granzyme B location in T cell secretory granule maintenance of protease location in mast cell secretory granule mast cell secretory granule organization modulation of chemical synaptic transmission n... |
bicarbonate transport blood coagulation chloride transmembrane transport chloride transport erythrocyte development negative regulation of glycolytic process through fructose-6-phosphate negative regulation of urine volume pH elevation plasma membrane phospholipid scrambling positive regulation of T cell proliferation ... | ankyrin-1 complex; basolateral plasma membrane; cell surface; cortical cytoskeleton; cytoplasmic side of plasma membrane; intercalated disc; membrane; plasma membrane; Z disc | actin binding ankyrin binding bicarbonate transmembrane transporter activity chloride transmembrane transporter activity chloride:bicarbonate antiporter activity enzyme binding hemoglobin binding protein homodimerization activity protein-containing complex binding solute:inorganic anion antiporter activity | Mus musculus | Acetylation Alternative splicing Anion exchange Cell membrane Direct protein sequencing Glycoprotein Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MGDMRDHEEV | MGDMRDHEEVLEIPDRDSEEELENIIGQIAYRDLTIPVTEMQDPEALPTEQTATDYVPSSTSTPHPSSGQVYVELQELMMDQRNQELQWVEAAHWIGLEENLREDGVWGRPHLSYLTFWSLLELQKVFSKGTFLLGLAETSLAGVANHLLDCFIYEDQIRPQDREELLRALLLKRSHAEDLGNLEGVKPAVLTRSGGASEPLLPHQPSLETQLYCGQAEGGSEGPSTSGTLKIPPDSETTLVLVGRANFLEKPVLGFVRLKEAVPLEDLVLPEPVGFLLVLLGPEAPHVDYTQLGRAAATLMTERVFRITASMAHNREEL... | bicarbonate transport blood coagulation chloride transmembrane transport chloride transport erythrocyte development negative regulation of glycolytic process through fructose-6-phosphate negative regulation of urine volume pH elevation plasma membrane phospholipid scrambling positive regulation of T cell proliferation ... |
aerobic respiration cellular response to lipid cellular response to testosterone stimulus energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insu... | cytosol; extracellular space; nucleus | insulin receptor activity odorant binding pheromone binding small molecule binding | Mus musculus | 3D-structure Behavior Disulfide bond Pheromone-binding Reference proteome Secreted Signal Transport | MKMLLLLLCL | MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE | aerobic respiration cellular response to lipid cellular response to testosterone stimulus energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insu... |
aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response... | cytosol; extracellular space; nucleus | insulin receptor activity odorant binding pheromone binding small molecule binding | Mus musculus | Disulfide bond Glycoprotein Pheromone-binding Reference proteome Secreted Signal Transport | MKLLLPLLLL | MKLLLPLLLLLCLELTLVCIHAEESSSMERNFNVEQISGYWFSIAEASYEREKIEEHGSMRAFVENITVLENSLVFKFHLIVNEECTEMTAIGEQTEKAGIYYMNYDGFNTFSILKTDYDNYIMIHLINKKDGKTFQLMELYGREPDLSLDIKEKFAKLCEEHGIIRENIIDLTNVNRCLEARE | aerobic respiration cellular response to lipid energy reserve metabolic process glucose homeostasis heat generation locomotor rhythm mitochondrion organization negative regulation of DNA-templated transcription negative regulation of gluconeogenesis negative regulation of insulin secretion involved in cellular response... |
absorption of UV light cellular response to light stimulus detection of UV G protein-coupled receptor signaling pathway phototransduction phototransduction, UV visual perception | membrane | G protein-coupled photoreceptor activity | Drosophila melanogaster | Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MESGNVSSSL | MESGNVSSSLFGNVSTALRPEARLSAETRLLGWNVPPEELRHIPEHWLTYPEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVKTPIFIYNSFHQGYALGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEGKMTHGKAIAMIIFIYMYATPWVVACYTETWGRFVPEGYLTSCTFDYLTDNFDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLRSNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAFGDKTLLTPGAT... | absorption of UV light cellular response to light stimulus detection of UV G protein-coupled receptor signaling pathway phototransduction phototransduction, UV visual perception membrane G protein-coupled photoreceptor activity Drosophila melanogaster Chromophore Disulfide bond G-protein coupled receptor Glycoprotein M... |
base-excision repair, gap-filling cellular response to hydrogen peroxide cellular response to UV cellular response to xenobiotic stimulus epithelial cell differentiation estrous cycle heart development leading strand elongation liver regeneration mismatch repair mitotic telomere maintenance via semi-conservative replic... | centrosome; chromatin; cyclin-dependent protein kinase holoenzyme complex; male germ cell nucleus; nuclear body; nuclear lamina; nuclear replication fork; nucleus; PCNA complex; PCNA-p21 complex; replication fork | chromatin binding damaged DNA binding dinucleotide insertion or deletion binding DNA polymerase binding DNA polymerase processivity factor activity enzyme binding histone acetyltransferase binding identical protein binding MutLalpha complex binding nuclear estrogen receptor binding protein-containing complex binding pu... | Rattus norvegicus | Acetylation DNA damage DNA repair DNA replication DNA-binding Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation | MFEARLIQGS | MFEARLIQGSILKKVLEALKDLINEACWDISSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVSIEMNEPVQLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS | base-excision repair, gap-filling cellular response to hydrogen peroxide cellular response to UV cellular response to xenobiotic stimulus epithelial cell differentiation estrous cycle heart development leading strand elongation liver regeneration mismatch repair mitotic telomere maintenance via semi-conservative replic... |
proteolysis | extracellular region | serine-type endopeptidase activity toxin activity | Bothrops atrox | Blood coagulation cascade activating toxin Disulfide bond Glycoprotein Hemostasis impairing toxin Hydrolase Pharmaceutical Protease Secreted Serine protease Signal Toxin Zymogen | MVLIRVIANL | MVLIRVIANLLILQVSYAQKSSELVIGGDECDINEHPFLAFMYYSPRYFCGMTLINQEWVLTAAHCNRRFMRIHLGKHAGSVANYDEVVRYPKEKFICPNKKKNVITDKDIMLIRLDRPVKNSEHIAPLSLPSNPPSVGSVCRIMGWGAITTSEDTYPDVPHCANINLFNNTVCREAYNGLPAKTLCAGVLQGGIDTCGGDSGGPLICNGQFQGILSWGSDPCAEPRKPAFYTKVFDYLPWIQSIIAGNKTATCP | proteolysis extracellular region serine-type endopeptidase activity toxin activity Bothrops atrox Blood coagulation cascade activating toxin Disulfide bond Glycoprotein Hemostasis impairing toxin Hydrolase Pharmaceutical Protease Secreted Serine protease Signal Toxin Zymogen MVLIRVIANL MVLIRVIANLLILQVSYAQKSSELVIGGDECD... |
positive regulation of epidermal growth factor receptor signaling pathway positive regulation of G protein-coupled receptor signaling pathway positive regulation of MAPK cascade response to stimulus visual perception | photoreceptor disc membrane; photoreceptor outer segment membrane | 3',5'-cyclic-GMP phosphodiesterase activity cGMP binding ion binding molecular adaptor activity zinc ion binding | Bos taurus | 3D-structure Acetylation cGMP Direct protein sequencing Hydrolase Reference proteome Sensory transduction Vision | MNLEPPKAEI | MNLEPPKAEIRSATRVMGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII | positive regulation of epidermal growth factor receptor signaling pathway positive regulation of G protein-coupled receptor signaling pathway positive regulation of MAPK cascade response to stimulus visual perception photoreceptor disc membrane; photoreceptor outer segment membrane 3',5'-cyclic-GMP phosphodiesterase ac... |
clathrin-dependent endocytosis intracellular protein transport | ciliary membrane; clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin vesicle coat; cytosol; plasma membrane; postsynaptic endocytic zone cytoplasmic component; synaptic vesicle membrane; trans-Golgi network | clathrin heavy chain binding structural molecule activity | Bos taurus | 3D-structure Acetylation Alternative splicing Calcium Coated pit Cytoplasmic vesicle Direct protein sequencing Disulfide bond Membrane Phosphoprotein Reference proteome | MADDFGFFSS | MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSQGGLAQPGPASGASEDMGATVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVMEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR | clathrin-dependent endocytosis intracellular protein transport ciliary membrane; clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin vesicle coat; cytosol; plasma membrane; postsynaptic endocytic zone cytoplasmic component; synaptic vesicle membrane; trans-Golgi network cl... |
D-ribose catabolic process | cytosol | D-ribose pyranase activity identical protein binding intramolecular lyase activity intramolecular transferase activity monosaccharide binding | Escherichia coli | Carbohydrate metabolism Cytoplasm Direct protein sequencing Isomerase Reference proteome | MKKGTVLNSD | MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKHHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF | D-ribose catabolic process cytosol D-ribose pyranase activity identical protein binding intramolecular lyase activity intramolecular transferase activity monosaccharide binding Escherichia coli Carbohydrate metabolism Cytoplasm Direct protein sequencing Isomerase Reference proteome MKKGTVLNSD MKKGTVLNSDISSVISRLGHTDTLVV... |
D-ribose transmembrane transport | ATP-binding cassette (ABC) transporter complex; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane | ABC-type D-ribose transporter activity ABC-type monosaccharide transporter activity ATP binding ATP hydrolysis activity D-ribose transmembrane transporter activity | Escherichia coli | ATP-binding Cell inner membrane Cell membrane Direct protein sequencing Membrane Nucleotide-binding Reference proteome Repeat Sugar transport Translocase Transport | MEALLQLKGI | MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFLGREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQFIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRS... | D-ribose transmembrane transport ATP-binding cassette (ABC) transporter complex; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; membrane ABC-type D-ribose transporter activity ABC-type monosaccharide transporter activity ATP binding ATP hydrolysis activity D-ribose transmembrane t... |
photorespiration reductive pentose-phosphate cycle | chloroplast | magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity | Petunia hybrida | Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Monooxygenase Oxidoreductase Photorespiration Photosynthesis Plastid | MSPQTETKAS | MSPQTETKASVGFKAGVKEYKLTYYTPEYQAKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGHRYRIERVIGERDQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLKATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRM... | photorespiration reductive pentose-phosphate cycle chloroplast magnesium ion binding monooxygenase activity ribulose-bisphosphate carboxylase activity Petunia hybrida Acetylation Calvin cycle Carbon dioxide fixation Chloroplast Direct protein sequencing Disulfide bond Lyase Magnesium Metal-binding Methylation Monooxyge... |
DNA damage response DNA recombination double-strand break repair via homologous recombination recombinational repair | exodeoxyribonuclease V complex | ATP binding ATP hydrolysis activity DNA binding exodeoxyribonuclease V activity helicase activity single-stranded DNA helicase activity | Escherichia coli | 3D-structure ATP-binding Direct protein sequencing DNA damage DNA repair DNA-binding Exonuclease Helicase Hydrolase Nuclease Nucleotide-binding Reference proteome | MKLQKQLLEA | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAG... | DNA damage response DNA recombination double-strand break repair via homologous recombination recombinational repair exodeoxyribonuclease V complex ATP binding ATP hydrolysis activity DNA binding exodeoxyribonuclease V activity helicase activity single-stranded DNA helicase activity Escherichia coli 3D-structure ATP-bi... |
DNA catabolic process mismatch repair | cytoplasm; exodeoxyribonuclease VII complex | DNA binding exodeoxyribonuclease VII activity | Escherichia coli | Cytoplasm Direct protein sequencing DNA-binding Exonuclease Hydrolase Nuclease Reference proteome | MLPSQSPAIF | MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPAAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFTSRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE... | DNA catabolic process mismatch repair cytoplasm; exodeoxyribonuclease VII complex DNA binding exodeoxyribonuclease VII activity Escherichia coli Cytoplasm Direct protein sequencing DNA-binding Exonuclease Hydrolase Nuclease Reference proteome MLPSQSPAIF MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNS... |
adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein regulati... | extracellular space | cytokine activity cytokine receptor binding type I interferon receptor binding | Homo sapiens | 3D-structure Antiviral defense Cytokine Direct protein sequencing Disulfide bond Glycoprotein Reference proteome Secreted Signal | MALLFPLLAA | MALLFPLLAALVMTSYSPVGSLGCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFRFPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHLETCLLQVVGEGESAGAISSPALTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTNMQERLRSKDRDLGSS | adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein regulati... |
adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein response... | extracellular region; extracellular space | cytokine activity type I interferon receptor binding | Homo sapiens | Antiviral defense Cytokine Direct protein sequencing Disulfide bond Reference proteome Secreted Signal | MALPFALLMA | MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFRFPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLEACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRNLQERLRRKE | adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein response... |
adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein response... | extracellular region; extracellular space | cytokine activity type I interferon receptor binding | Homo sapiens | Antiviral defense Cytokine Direct protein sequencing Disulfide bond Reference proteome Secreted Signal | MALSFSLLMA | MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFGFPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD | adaptive immune response B cell differentiation B cell proliferation cellular response to virus cytokine-mediated signaling pathway defense response to virus humoral immune response natural killer cell activation involved in immune response positive regulation of peptidyl-serine phosphorylation of STAT protein response... |
de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process pyrimidine nucleotide biosynthetic process | cytoplasm; cytosol | dihydroorotase activity protein homodimerization activity zinc ion binding | Escherichia coli | 3D-structure Direct protein sequencing Hydrolase Metal-binding Pyrimidine biosynthesis Reference proteome Zinc | MTAPSQVLKI | MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQ... | de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process pyrimidine nucleotide biosynthetic process cytoplasm; cytosol dihydroorotase activity protein homodimerization activity zinc ion binding Escherichia coli 3D-structure Direct protein sequencing Hydrolase Metal-binding Pyrimidine biosy... |
cardiac muscle cell action potential involved in contraction cell communication by electrical coupling involved in cardiac conduction cellular response to steroid hormone stimulus establishment or maintenance of transmembrane electrochemical gradient intracellular potassium ion homeostasis intracellular sodium ion home... | apical plasma membrane; axon; basolateral plasma membrane; endoplasmic reticulum; extracellular exosome; extracellular vesicle; Golgi apparatus; lateral plasma membrane; melanosome; membrane; membrane raft; organelle membrane; photoreceptor inner segment membrane; plasma membrane; postsynaptic density; protein-containi... | ATP binding ATP hydrolysis activity P-type sodium:potassium-exchanging transporter activity phosphatase activity potassium ion binding protein heterodimerization activity protein-folding chaperone binding sodium ion binding steroid hormone binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Cell membrane Cell projection Charcot-Marie-Tooth disease Direct protein sequencing Epilepsy Intellectual disability Ion transport Magnesium Membrane Metal-binding Neurodegeneration Neuropathy Nucleotide-binding Phosphoprotein Potassium Potassium transport Prima... | MGKGVGRDKY | MGKGVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEA... | cardiac muscle cell action potential involved in contraction cell communication by electrical coupling involved in cardiac conduction cellular response to steroid hormone stimulus establishment or maintenance of transmembrane electrochemical gradient intracellular potassium ion homeostasis intracellular sodium ion home... |
establishment or maintenance of transmembrane electrochemical gradient intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization potassium ion import across plasma membrane proton transmembrane transport regulation of sodium ion transport sodium ion export across plasma membra... | axon; basolateral plasma membrane; melanosome; membrane; plasma membrane; sarcolemma; sodium:potassium-exchanging ATPase complex | ATP binding ATP hydrolysis activity ATPase binding P-type sodium:potassium-exchanging transporter activity potassium ion binding sodium ion binding | Sus scrofa | 3D-structure Acetylation ATP-binding Cell membrane Cell projection Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Sodium Sodium transport Sodium/potassium transport Translocase Transmembrane Transmembrane helix Transport | MGKGVGRDKY | MGKGVGRDKYEPAAVSEHGDKKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTPARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVI... | establishment or maintenance of transmembrane electrochemical gradient intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization potassium ion import across plasma membrane proton transmembrane transport regulation of sodium ion transport sodium ion export across plasma membra... |
ATP metabolic process cardiac muscle contraction cell adhesion establishment or maintenance of transmembrane electrochemical gradient innate immune response intracellular calcium ion homeostasis intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization positive regulation of P... | apical plasma membrane; basolateral plasma membrane; intercalated disc; lateral plasma membrane; organelle membrane; sodium:potassium-exchanging ATPase complex; sperm flagellum; T-tubule | ATPase activator activity ATPase binding P-type sodium:potassium-exchanging transporter activity protein kinase binding protein-macromolecule adaptor activity | Sus scrofa | 3D-structure Cell adhesion Cell membrane Disulfide bond Glutathionylation Glycoprotein Immunity Innate immunity Ion transport Membrane Phosphoprotein Potassium Potassium transport Reference proteome Signal-anchor Sodium Sodium transport Sodium/potassium transport Transmembrane Transmembrane helix Transport | MARGKAKEEG | MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQSQKTEISFRPNDPQSYESYVVSIVRFLEKYKDLAQKDDMIFEDCGNVPSELKERGEYNNERGERKVCRFRLEWLGNCSGLNDETYGYKDGKPCVIIKLNRVLGFKPKPPKNESLETYPVMKYNPYVLPVHCTGKRDEDKEKVGTMEYFGLGGYPGFPLQYYPYYGKLLQPKYLQPLMAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIEVKS | ATP metabolic process cardiac muscle contraction cell adhesion establishment or maintenance of transmembrane electrochemical gradient innate immune response intracellular calcium ion homeostasis intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization positive regulation of P... |
ATP metabolic process cardiac muscle contraction cell adhesion innate immune response intracellular calcium ion homeostasis intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization positive regulation of potassium ion import across plasma membrane positive regulation of sodiu... | apical plasma membrane; basolateral plasma membrane; intercalated disc; lateral plasma membrane; organelle membrane; sodium:potassium-exchanging ATPase complex; sperm flagellum; T-tubule | ATPase activator activity ATPase binding P-type sodium:potassium-exchanging transporter activity protein kinase binding protein-macromolecule adaptor activity | Ovis aries | Cell adhesion Cell membrane Disulfide bond Glutathionylation Glycoprotein Immunity Innate immunity Ion transport Membrane Phosphoprotein Potassium Potassium transport Reference proteome Signal-anchor Sodium Sodium transport Sodium/potassium transport Transmembrane Transmembrane helix Transport | MARGKAKEEG | MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQIQKTEIAFRPNDPKSYMTYVDNIDNFLKKYRDSAQKDDMIFEDCGNVPSELKDRGEFNNEQGERKVCRFKLEWLGNCSGINDETYGYKEGKPCVIIKLNRVLGFKPKPPKNESLETYPVMKYNPYVLPVQCTGKRDEDKEKVGSIEYFGLGGYPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIEVKS | ATP metabolic process cardiac muscle contraction cell adhesion innate immune response intracellular calcium ion homeostasis intracellular potassium ion homeostasis intracellular sodium ion homeostasis membrane repolarization positive regulation of potassium ion import across plasma membrane positive regulation of sodiu... |
positive regulation of TORC1 signaling proteasome storage granule assembly proton export across plasma membrane proton transmembrane transport regulation of intracellular pH transmembrane transport | cytosol; eisosome; membrane raft; mitochondrion; plasma membrane | ATP binding ATP hydrolysis activity metal ion binding P-type proton-exporting transporter activity | Saccharomyces cerevisiae | 3D-structure Amyloid ATP-binding Cell membrane Direct protein sequencing Hydrogen ion transport Ion transport Isopeptide bond Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Prion Reference proteome Translocase Transmembrane Transmembrane helix Transport Ubl conjugation | MTDTSSSSSS | MTDTSSSSSSSSASSVSAHQPTQEKPAKTYDDAASESSDDDDIDALIEELQSNHGVDDEDSDNDGPVAAGEARPVPEEYLQTDPSYGLTSDEVLKRRKKYGLNQMADEKESLVVKFVMFFVGPIQFVMEAAAILAAGLSDWVDFGVICGLLMLNAGVGFVQEFQAGSIVDELKKTLANTAVVIRDGQLVEIPANEVVPGDILQLEDGTVIPTDGRIVTEDCFLQIDQSAITGESLAVDKHYGDQTFSSSTVKRGEGFMVVTATGDNTFVGRAAALVNKAAGGQGHFTEVLNGIGIILLVLVIATLLLVWTACFYRTNGIV... | positive regulation of TORC1 signaling proteasome storage granule assembly proton export across plasma membrane proton transmembrane transport regulation of intracellular pH transmembrane transport cytosol; eisosome; membrane raft; mitochondrion; plasma membrane ATP binding ATP hydrolysis activity metal ion binding P-t... |
adult chitin-containing cuticle pigmentation anesthesia-resistant memory catecholamine metabolic process dopamine biosynthetic process from tyrosine long-term memory regulation of adult chitin-containing cuticle pigmentation response to hydrogen peroxide response to wounding serotonin biosynthetic process serotonin bio... | cytoplasm | 5-hydroxy-L-tryptophan decarboxylase activity aromatic-L-amino-acid decarboxylase activity L-dopa decarboxylase activity pyridoxal phosphate binding | Drosophila melanogaster | 3D-structure Alternative splicing Catecholamine biosynthesis Decarboxylase Lyase Pyridoxal phosphate Reference proteome | MSHIPISNTI | MSHIPISNTIPTKQTDGNGKANISPDKLDPKVSIDMEAPEFKDFAKTMVDFIAEYLENIRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDIERVIMPGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKMLELPAEFLACSGGKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTILGKLVGYCSDQAHSSVERAGLLGGVKLRSVQSENHRMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAFDYLDECGPVGNKHNLWIHVDAAYAGSAFICPEYRH... | adult chitin-containing cuticle pigmentation anesthesia-resistant memory catecholamine metabolic process dopamine biosynthetic process from tyrosine long-term memory regulation of adult chitin-containing cuticle pigmentation response to hydrogen peroxide response to wounding serotonin biosynthetic process serotonin bio... |
folic acid biosynthetic process para-aminobenzoic acid biosynthetic process tetrahydrofolate biosynthetic process tryptophan biosynthetic process | aminodeoxychorismate synthase complex | 4-amino-4-deoxychorismate synthase activity magnesium ion binding protein heterodimerization activity tryptophan binding | Escherichia coli | 3D-structure Direct protein sequencing Folate biosynthesis Magnesium Reference proteome Transferase | MKTLSPAVIT | MKTLSPAVITLLWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDVNARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPDPQEDSKQAVKLANSAKDRAENLMIVDLMRNDIGRVAVA... | folic acid biosynthetic process para-aminobenzoic acid biosynthetic process tetrahydrofolate biosynthetic process tryptophan biosynthetic process aminodeoxychorismate synthase complex 4-amino-4-deoxychorismate synthase activity magnesium ion binding protein heterodimerization activity tryptophan binding Escherichia col... |
fumarate metabolic process malate metabolic process response to oxidative stress tricarboxylic acid cycle | tricarboxylic acid cycle enzyme complex | fumarate hydratase activity identical protein binding | Escherichia coli | 3D-structure Allosteric enzyme Cytoplasm Direct protein sequencing Lyase Reference proteome Tricarboxylic acid cycle | MNTVRSEKDS | MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSI... | fumarate metabolic process malate metabolic process response to oxidative stress tricarboxylic acid cycle tricarboxylic acid cycle enzyme complex fumarate hydratase activity identical protein binding Escherichia coli 3D-structure Allosteric enzyme Cytoplasm Direct protein sequencing Lyase Reference proteome Tricarboxyl... |
DNA dealkylation involved in DNA repair DNA demethylation DNA repair oxidative demethylation oxidative RNA demethylation oxidative single-stranded DNA demethylation oxidative single-stranded RNA demethylation response to methyl methanesulfonate RNA repair | cytoplasm | dioxygenase activity DNA-N1-methyladenine dioxygenase activity ferrous iron binding oxidative DNA demethylase activity oxidative RNA demethylase activity | Escherichia coli | 3D-structure Dioxygenase Direct protein sequencing DNA damage DNA repair Iron Metal-binding Oxidoreductase Reference proteome | MLDLFADAEP | MLDLFADAEPWQEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLKRNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTIDCRYNLTFRQAGKKE | DNA dealkylation involved in DNA repair DNA demethylation DNA repair oxidative demethylation oxidative RNA demethylation oxidative single-stranded DNA demethylation oxidative single-stranded RNA demethylation response to methyl methanesulfonate RNA repair cytoplasm dioxygenase activity DNA-N1-methyladenine dioxygenase ... |
mRNA catabolic process response to heat RNA catabolic process RNA processing | bacterial degradosome; cytosol; membrane | 3'-5'-RNA exonuclease activity cyclic-di-GMP binding identical protein binding magnesium ion binding polyribonucleotide nucleotidyltransferase activity RNA binding | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing Magnesium Metal-binding Nucleotidyltransferase Reference proteome RNA-binding Stress response Transferase | MLNPIVRKFQ | MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAQLLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGRE... | mRNA catabolic process response to heat RNA catabolic process RNA processing bacterial degradosome; cytosol; membrane 3'-5'-RNA exonuclease activity cyclic-di-GMP binding identical protein binding magnesium ion binding polyribonucleotide nucleotidyltransferase activity RNA binding Escherichia coli 3D-structure Cytoplas... |
adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation defense response to bacterium defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium innate immune response killing of cells of another organism mast cell ... | chromaffin granule; extracellular region; extracellular space; neuronal dense core vesicle; secretory granule; transport vesicle | calcium ion binding metal ion binding | Bos taurus | 3D-structure Amidation Antibiotic Antimicrobial Calcium Cleavage on pair of basic residues Cytoplasmic vesicle Direct protein sequencing Disulfide bond Fungicide Glycoprotein Oxidation Phosphoprotein Proteoglycan Reference proteome Secreted Signal | MRSAAVLALL | MRSAAVLALLLCAGQVIALPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSKECFETLRGDERILSILRHQNLLKELQDLALQGAKERTHQQKKHSSYEDELSEVLEKPNDQAEPKEVTEEVSSKDAAEKRDDFKEVEKSDEDSDGDRPQASPGLGPGPKVEEDNQAPGEEEEAPSNAHPLASLPSPKYPGPQAKEDSEGPSQGPASREKGLSAEQGRQTEREEEEEKWEEAEAREKAVPEEESPPTAAFKPPPSLGNKETQRAAPGWPEDGAGKMGAEEAKPPEGKGEWAHSRQEEEEMARAPQVLFRGGKSGEPEQ... | adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation defense response to bacterium defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium innate immune response killing of cells of another organism mast cell ... |
fructose 1,6-bisphosphate metabolic process fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate fructose metabolic process gluconeogenesis glycolytic process NADH oxidation negative regulation of pentose-phosphate shunt positive regulation of ATP-dependent activity vacuolar proton-tran... | centriolar satellite; cytosol; extracellular exosome; microtubule organizing center | ATPase binding cytoskeletal protein binding fructose binding fructose-1-phosphate aldolase activity fructose-bisphosphate aldolase activity identical protein binding molecular adaptor activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Glycolysis Lyase Phosphoprotein Reference proteome Schiff base | MAHRFPALTQ | MAHRFPALTQEQKKELSEIAQSIVANGKGILAADESVGTMGNRLQRIKVENTEENRRQFREILFSVDSSINQSIGGVILFHETLYQKDSQGKLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANALARYASICQQNGLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAAN... | fructose 1,6-bisphosphate metabolic process fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate fructose metabolic process gluconeogenesis glycolytic process NADH oxidation negative regulation of pentose-phosphate shunt positive regulation of ATP-dependent activity vacuolar proton-tran... |
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