Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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anterior/posterior axis specification, embryo bicoid mRNA localization oogenesis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sexual reproduction | cytosol; nucleus; polytene chromosome interband | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | 3D-structure Activator Developmental protein DNA-binding Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MDTCFFCGAV | MDTCFFCGAVDLSDTGSSSSMRYETLSAKVPSSQKTVSLVLTHLANCIQTQLDLKPGARLCPRCFQELSDYDTIMVNLMTTQKRLTTQLKGALKSEFEVPESGEDILVEEVEIPQSDVETDADAEADALFVELVKDQEESDTEIKREFVDEEEEEDDDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVKQECTTCGKVYNSWYQLQKHISEEHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSR... | anterior/posterior axis specification, embryo bicoid mRNA localization oogenesis positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sexual reproduction cytosol; nucleus; polytene chromosome interband DNA binding DNA-binding transcription activator activity, RNA po... |
acetylcholine biosynthetic process neuromuscular synaptic transmission | cytoplasm; cytosol; neuron projection; nucleus; terminal bouton | choline O-acetyltransferase activity | Drosophila melanogaster | Acyltransferase Alternative splicing Direct protein sequencing Neurotransmitter biosynthesis Reference proteome Transferase | MASNEASTSA | MASNEASTSAAGSGPESAALFSKLRSFSIGSGPNSPQRVVSNLRGFLTHRLSNITPSDTGWKDSILSIPKKWLSTAESVDEFGFPDTLPKVPVPALDETMADYIRALEPITTPAQLERTKELIRQFSAPQGIGARLHQYLLDKREAEDNWAYYYWLNEMYMDIRIPLPINSNPGMVFPPRRFKTVHDVAHFAARLLDGILSHREMLDSGELPLERAASREKNQPLCMAQYYRLLGSCRRPGVKQDSQFLPSRERLNDEDRHVVVICRNQMYCVVLQASDRGKLSESEIASQILYVLSDAPCLPAKPVPVGLLTAEPRSTW... | acetylcholine biosynthetic process neuromuscular synaptic transmission cytoplasm; cytosol; neuron projection; nucleus; terminal bouton choline O-acetyltransferase activity Drosophila melanogaster Acyltransferase Alternative splicing Direct protein sequencing Neurotransmitter biosynthesis Reference proteome Transferase ... |
canonical glycolysis gluconeogenesis glyceraldehyde-3-phosphate biosynthetic process glycerol catabolic process glycolytic process | cytosol; nucleus | triose-phosphate isomerase activity | Schizosaccharomyces pombe | 3D-structure Gluconeogenesis Glycolysis Isomerase Phosphoprotein Reference proteome | MARKFFVGGN | MARKFFVGGNFKMNGSLESMKTIIEGLNTTKLNVGDVETVIFPQNMYLITTRQQVKKDIGVGAQNVFDKKNGAYTGENSAQSLIDAGITYTLTGHSERRTIFKESDEFVADKTKFALEQGLTVVACIGETLAEREANETINVVVRQLNAIADKVQNWSKIVIAYEPVWAIGTGKTATPEQAQEVHAEIRKWATNKLGASVAEGLRVIYGGSVNGGNCKEFLKFHDIDGFLVGGASLKPEFHNIVNVHSL | canonical glycolysis gluconeogenesis glyceraldehyde-3-phosphate biosynthetic process glycerol catabolic process glycolytic process cytosol; nucleus triose-phosphate isomerase activity Schizosaccharomyces pombe 3D-structure Gluconeogenesis Glycolysis Isomerase Phosphoprotein Reference proteome MARKFFVGGN MARKFFVGGNFKMN... |
DNA replication plasmid maintenance | plasma membrane | DNA binding | Escherichia coli | Alternative initiation Cell inner membrane Cell membrane DNA replication DNA-binding Membrane Plasmid Plasmid copy control | MNRTFDRKAY | MNRTFDRKAYRQELIDAGFSAEDAETIASRTVMRAPRETFQSVGSMVQQATAKIERDSVQLAPPALPAPSAAVERSRRLEQEAAGLAKSMTIDTRGTMTTKKRKTAGEDLAKQVSEAKQAALLKHTKQQIKEMQLSLFDIAPWPDTMRAMPNDTARSALFTTRNKKIPREALQNKVIFHVNKDVKITYTGVELRADDDELVWQQVLEYAKRTPIGEPITFTFYELCQDLGWSINGRYYTKAEECLSRLQATAMGFTSDRVGHLESVSLLHRFRVLDRGKKTSRCQVLIDEEIVVLFAGDHYTKFIWEKYRKLSPTARRMF... | DNA replication plasmid maintenance plasma membrane DNA binding Escherichia coliAlternative initiation Cell inner membrane Cell membrane DNA replication DNA-binding Membrane Plasmid Plasmid copy control MNRTFDRKAY MNRTFDRKAYRQELIDAGFSAEDAETIASRTVMRAPRETFQSVGSMVQQATAKIERDSVQLAPPALPAPSAAVERSRRLEQEAAGLAKSMTIDTRGTMTTKKRKTA... |
histidine biosynthetic process | cytoplasm | ATP binding histidinol dehydrogenase activity metal ion binding NAD binding phosphoribosyl-AMP cyclohydrolase activity phosphoribosyl-ATP diphosphatase activity | Neurospora crassa | Amino-acid biosynthesis ATP-binding Histidine biosynthesis Hydrolase Metal-binding Multifunctional enzyme NAD Nucleotide-binding Oxidoreductase Reference proteome Zinc | METTLPLPFL | METTLPLPFLVGVSVPPGLNDIKEGLSREEVSCLGCVFFEVKPQTLEKILRFLKRHNVEFEPYFDVTALESIDDIITLLDAGARKVFVKTEQLADLSAYGSRVAPIVTGSSAALLSSATESGLLLSGFDQTASEAAQFLEEARDKKITPFFIKPVPGADLEQFIQVAAKANAIPILPSTGLTTKKDEAGKLAISTILSSVWKSDRPDGLLPTVVVDEHDTALGLVYSSAESVNEALRTQTGVYQSRKRGLWYKGATSGDTQELVRISLDCDNDALKFVVKQKGRFCHLDQSGCFGQLKGLPKLEQTLISRKQSAPEGSYT... | histidine biosynthetic process cytoplasm ATP binding histidinol dehydrogenase activity metal ion binding NAD binding phosphoribosyl-AMP cyclohydrolase activity phosphoribosyl-ATP diphosphatase activity Neurospora crassa Amino-acid biosynthesis ATP-binding Histidine biosynthesis Hydrolase Metal-binding Multifunctional e... |
astrocyte cell migration chondroitin sulfate catabolic process dermatan sulfate catabolic process ganglioside catabolic process glycosaminoglycan metabolic process hyaluronan catabolic process intracellular calcium ion homeostasis lipid storage locomotory behavior lysosome organization maintenance of location in cell m... | acrosomal vesicle; azurophil granule; azurophil granule lumen; beta-N-acetylhexosaminidase complex; cortical granule; extracellular exosome; extracellular region; lysosomal lumen; lysosome; membrane | acetylglucosaminyltransferase activity beta-N-acetylhexosaminidase activity identical protein binding N-acetyl-beta-D-galactosaminidase activity | Homo sapiens | 3D-structure Cytoplasmic vesicle Direct protein sequencing Disease variant Disulfide bond Gangliosidosis Glycoprotein Glycosidase Hydrolase Lipid metabolism Lysosome Neurodegeneration Reference proteome Signal Zymogen | MELCGLGLPR | MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEAARAPSVSAKPGPALWPLPLLVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHGYIFGFYKWHHEPAEFQAKTQVQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVYQDSYGTFTINESTIIDSPRFSHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSITFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFG... | astrocyte cell migration chondroitin sulfate catabolic process dermatan sulfate catabolic process ganglioside catabolic process glycosaminoglycan metabolic process hyaluronan catabolic process intracellular calcium ion homeostasis lipid storage locomotory behavior lysosome organization maintenance of location in cell m... |
arachidonic acid metabolic process aromatic compound catabolic process cellular aromatic compound metabolic process cellular response to glucocorticoid stimulus cellular response to organic substance diol biosynthetic process epoxide metabolic process liver development response to organic cyclic compound response to to... | endoplasmic reticulum membrane; intracellular membrane-bounded organelle; membrane | cis-stilbene-oxide hydrolase activity enzyme binding epoxide hydrolase activity oxysterol binding | Rattus norvegicus | Acetylation Aromatic hydrocarbons catabolism Detoxification Endoplasmic reticulum Hydrolase Lipid metabolism Membrane Methylation Microsome Reference proteome Signal-anchor Transmembrane Transmembrane helix | MWLELVLASL | MWLELVLASLLGFVIYWFVSRDKEETLPLGDGWWGPGSKPSAKEDESIRPFKVETSDEEIKDLHQRIDRFRASPPLEGSRFHYGFNSNYMKKVVSYWRNEFDWRKQVEILNQYPHFKTKIEGLDIHFIHVKPPQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKSHGLSDEHVFEVICPSIPGYGYSEASSKKGLNSVATARIFYKLMTRLGFQKFYIQGGDWGSLICTNMAQMVPNHVKGLHLNMAFISRSFYTMTPLLGQRFGRFLGYTEKDIELLYPYKEKVFYSIMRESGYLHIQATKPDTVGCALNDSPVG... | arachidonic acid metabolic process aromatic compound catabolic process cellular aromatic compound metabolic process cellular response to glucocorticoid stimulus cellular response to organic substance diol biosynthetic process epoxide metabolic process liver development response to organic cyclic compound response to to... |
cellular response to thyroid hormone stimulus collagen catabolic process decidualization epithelial cell differentiation proteolysis involved in protein catabolic process thyroid hormone generation viral entry into host cell | apical plasma membrane; external side of plasma membrane; extracellular space; lysosome; melanosome; peptidase inhibitor complex; perinuclear region of cytoplasm | collagen binding cysteine-type endopeptidase activity endopeptidase activity proteoglycan binding | Bos taurus | 3D-structure Acetylation Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Membrane Protease Reference proteome Secreted Signal Thiol protease Zymogen | MWRLLATLSC | MWRLLATLSCLLVLTSARSSLYFPPLSDELVNFVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGPKLPQRDAFAADVVLPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDMLTCCGGECGDGCNGGFPSGAWNFWTKKGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQDHCG... | cellular response to thyroid hormone stimulus collagen catabolic process decidualization epithelial cell differentiation proteolysis involved in protein catabolic process thyroid hormone generation viral entry into host cell apical plasma membrane; external side of plasma membrane; extracellular space; lysosome; melano... |
acetylcholine catabolic process in synaptic cleft | plasma membrane; side of membrane; synapse; synaptic cleft | acetylcholinesterase activity | Torpedo marmorata | Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Neurotransmitter degradation Serine esterase Signal Synapse | MREMNLLVTS | MREMNLLVTSSLGVLLHLVVLCQADDDSELLVNTKSGKVMRTRIPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFPGSEMWNPNREMSEDCLYLNIWVPSPRPKSATVMLWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNMGLLDQRMALQWVHDNIQFFGGDPKTVTLFGESAGRASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELRRNLNCNLNSDEDLIQCLREKKPQELIDVEWNVLPFDSIFRFSFVPVI... | acetylcholine catabolic process in synaptic cleft plasma membrane; side of membrane; synapse; synaptic cleft acetylcholinesterase activity Torpedo marmorata Alternative splicing Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Neurotransmitter degradation Ser... |
adenylate cyclase-activating adrenergic receptor signaling pathway positive regulation of GTPase activity positive regulation of heart contraction regulation of circadian sleep/wake cycle, sleep | early endosome; membrane; plasma membrane | beta1-adrenergic receptor activity identical protein binding | Meleagris gallopavo | 3D-structure Cell membrane Disulfide bond Endosome G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MGDGWLPPDC | MGDGWLPPDCGPHNRSGGGGATAAPTGSRQVSAELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGRTQRLQTLTNLFITSLACADLVMGLLVVPFGATLVVRGTWLWGSFLCECWTSLDVLCVTASIETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVYLRVYREAKEQIRKIDRCEGRFYGSQEQPQPPPLPQHQPILGNGRASKRKTSRVMAMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLV... | adenylate cyclase-activating adrenergic receptor signaling pathway positive regulation of GTPase activity positive regulation of heart contraction regulation of circadian sleep/wake cycle, sleep early endosome; membrane; plasma membrane beta1-adrenergic receptor activity identical protein binding Meleagris gallopavo 3D... |
nucleolar large rRNA transcription by RNA polymerase I ribosome biogenesis termination of RNA polymerase I transcription termination of RNA polymerase III transcription transcription by RNA polymerase I transcription by RNA polymerase III transcription elongation by RNA polymerase I transcription initiation at RNA poly... | nucleoplasm; nucleus; RNA polymerase I complex; RNA polymerase III complex | DNA binding protein dimerization activity RNA polymerase I activity RNA polymerase III activity | Saccharomyces cerevisiae | 3D-structure Acetylation DNA-directed RNA polymerase Nucleus Phosphoprotein Reference proteome Ribosome biogenesis Transcription | MSNIVGIEYN | MSNIVGIEYNRVTNTTSTDFPGFSKDAENEWNVEKFKKDFEVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNNAHVYARDLKFEPQGRQSTTFADCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSREVLRYEEFADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRI... | nucleolar large rRNA transcription by RNA polymerase I ribosome biogenesis termination of RNA polymerase I transcription termination of RNA polymerase III transcription transcription by RNA polymerase I transcription by RNA polymerase III transcription elongation by RNA polymerase I transcription initiation at RNA poly... |
adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen CD4-positive, alpha-beta T cell lineage commitment cellular response to thyroid hormone stimulus collagen catabolic proces... | apical plasma membrane; chromaffin granule; collagen-containing extracellular matrix; endocytic vesicle lumen; endolysosome lumen; extracellular exosome; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bounded organelle; lysosomal lumen; lysosome; multivesicular body; nucleus; plasma ... | collagen binding cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase activity cysteine-type peptidase activity fibronectin binding histone binding proteoglycan binding serpin family protein binding | Homo sapiens | 3D-structure Alternative initiation Cell membrane Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Host-virus interaction Hydrolase Lysosome Membrane Nucleus Protease Reference proteome Secreted Signal Thiol protease Zymogen | MNPTLILAAF | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRN... | adaptive immune response antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of peptide antigen CD4-positive, alpha-beta T cell lineage commitment cellular response to thyroid hormone stimulus collagen catabolic proces... |
axon regeneration cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules cellular response to mechanical stimulus central nervous system myelin formation central nervous system myelination myelination negative regulation of axon extension negative regulation of neuron apoptotic process negative regulat... | compact myelin; membrane raft; mesaxon; myelin sheath; myelin sheath adaxonal region; paranode region of axon; plasma membrane; Schmidt-Lanterman incisure | carbohydrate binding ganglioside GT1b binding protein homodimerization activity protein kinase binding sialic acid binding signaling receptor binding | Rattus norvegicus | Alternative splicing Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunoglobulin domain Lectin Lipid-binding Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MIFLTTLPLF | MIFLTTLPLFWIMISASRGGHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSTLSPELGGKYYFRGDLGGYNQYTFSEHSVLDIINTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPTVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQAAFPNTTLQFEGYASLDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGMVLREAVAESLYLDLEEVTPAEDGIYACLAENAYGQDNRTVEL... | axon regeneration cell adhesion cell-cell adhesion via plasma-membrane adhesion molecules cellular response to mechanical stimulus central nervous system myelin formation central nervous system myelination myelination negative regulation of axon extension negative regulation of neuron apoptotic process negative regulat... |
cellular response to calcium ion starvation cellular response to starvation negative regulation of mitochondrial depolarization positive regulation of circadian sleep/wake cycle, non-REM sleep | basement membrane; cytoplasm; endoplasmic reticulum; extracellular exosome; extracellular region; extracellular space; Golgi apparatus; myelin sheath; protein-containing complex | DNA binding enterobactin binding enzyme binding exogenous protein binding fatty acid binding identical protein binding modified amino acid binding oxygen binding protein-folding chaperone binding pyridoxal phosphate binding toxic substance binding zinc ion binding | Mus musculus | Calcium Cleavage on pair of basic residues Copper Direct protein sequencing Disulfide bond Lipid-binding Metal-binding Methylation Phosphoprotein Reference proteome Repeat Secreted Signal Zinc | MKWVTFLLLL | MKWVTFLLLLFVSGSAFSRGVFRREAHKSEIAHRYNDLGEQHFKGLVLIAFSQYLQKCSYDEHAKLVQEVTDFAKTCVADESAANCDKSLHTLFGDKLCAIPNLRENYGELADCCTKQEPERNECFLQHKDDNPSLPPFERPEAEAMCTSFKENPTTFMGHYLHEVARRHPYFYAPELLYYAEQYNEILTQCCAEADKESCLTPKLDGVKEKALVSSVRQRMKCSSMQKFGERAFKAWAVARLSQTFPNADFAEITKLATDLTKVNKECCHGDLLECADDRAELAKYMCENQATISSKLQTCCDKPLLKKAHCLSEVEHD... | cellular response to calcium ion starvation cellular response to starvation negative regulation of mitochondrial depolarization positive regulation of circadian sleep/wake cycle, non-REM sleep basement membrane; cytoplasm; endoplasmic reticulum; extracellular exosome; extracellular region; extracellular space; Golgi ap... |
calcium-mediated signaling cell surface receptor signaling pathway cytotoxic T cell differentiation defense response to virus positive regulation of calcium-mediated signaling T cell activation T cell mediated immunity T cell receptor signaling pathway | cell surface; external side of plasma membrane; plasma membrane; plasma membrane raft; receptor complex | identical protein binding MHC class I protein complex binding protein kinase binding | Rattus norvegicus | Adaptive immunity Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Lipoprotein Membrane Palmitate Reference proteome Signal Transmembrane Transmembrane helix | MASRVICFLS | MASRVICFLSLNLLLLDVITRLQVSGQLQLSPKKVDAEIGQEVKLTCEVLRDTSQGCSWLFRNSSSELLQPTFIIYVSSSRSKLNDILDPNLFSARKENNKYILTLSKFSTKNQGYYFCSITSNSVMYFSPLVPVFQKVNSIITKPVTRAPTPVPPPTGTPRPLRPEACRPGASGSVEGMGLGFACDIYIWAPLAGICAVLLLSLVITLICCHRNRRRVCKCPRPLVKPRPSEKFV | calcium-mediated signaling cell surface receptor signaling pathway cytotoxic T cell differentiation defense response to virus positive regulation of calcium-mediated signaling T cell activation T cell mediated immunity T cell receptor signaling pathway cell surface; external side of plasma membrane; plasma membrane; pl... |
acrosome reaction adult walking behavior cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chemical synaptic transmission chloride transmembrane transport chloride transport inhibitory postsynaptic potential monoatomic anion transport monoatomic ion transport muscle con... | calyx of Held; chloride channel complex; dendrite; endoplasmic reticulum; external side of plasma membrane; glycinergic synapse; inhibitory synapse; intracellular membrane-bounded organelle; membrane; neuron projection; neuronal cell body; perikaryon; plasma membrane; postsynaptic membrane; postsynaptic specialization ... | extracellularly glycine-gated chloride channel activity extracellularly glycine-gated ion channel activity glycine binding identical protein binding ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential protein-containing complex binding taurine binding transmembrane sign... | Rattus norvegicus | Alternative splicing Cell membrane Cell projection Chloride Chloride channel Direct protein sequencing Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Metal-binding Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport Z... | MYSFNTLRFY | MYSFNTLRFYLWETIVFFSLAASKEADAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL... | acrosome reaction adult walking behavior cellular response to amino acid stimulus cellular response to ethanol cellular response to zinc ion chemical synaptic transmission chloride transmembrane transport chloride transport inhibitory postsynaptic potential monoatomic anion transport monoatomic ion transport muscle con... |
actin cytoskeleton organization modification of postsynaptic actin cytoskeleton modulation of chemical synaptic transmission negative regulation of actin filament bundle assembly negative regulation of actin filament polymerization negative regulation of stress fiber assembly neural tube closure positive regulation of ... | blood microparticle; cell cortex; cytoplasm; cytoskeleton; cytosol; extracellular exosome; focal adhesion; glutamatergic synapse; membrane; nucleus | actin binding actin monomer binding adenyl-nucleotide exchange factor activity cadherin binding phosphatidylinositol-4,5-bisphosphate binding phosphotyrosine residue binding proline-rich region binding RNA binding small GTPase binding | Homo sapiens | 3D-structure Acetylation Actin-binding Amyotrophic lateral sclerosis Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Isopeptide bond Neurodegeneration Phosphoprotein Reference proteome Ubl conjugation | MAGWNAYIDN | MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFYVNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY | actin cytoskeleton organization modification of postsynaptic actin cytoskeleton modulation of chemical synaptic transmission negative regulation of actin filament bundle assembly negative regulation of actin filament polymerization negative regulation of stress fiber assembly neural tube closure positive regulation of ... |
carbohydrate derivative catabolic process carbohydrate metabolic process defense response to protozoan erythrocyte development establishment of blood-brain barrier glycolytic process neuroinflammatory response oxygen transport respiratory gaseous exchange by respiratory system | cytosol; extracellular exosome | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity bisphosphoglycerate mutase activity hydrolase activity | Homo sapiens | 3D-structure Acetylation Congenital erythrocytosis Direct protein sequencing Disease variant Glycation Glycolysis Glycoprotein Hereditary hemolytic anemia Hydrolase Isomerase Phosphoprotein Reference proteome | MSKYKLIMLR | MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSEGMEEARNCGKQLKALNFEFDLVFTSVLNRSIHTAWLILEELGQEWVPVESSWRLNERHYGALIGLNREQMALNHGEEQVRLWRRSYNVTPPPIEESHPYYQEIYNDRRYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRGKTILISAHGNSSRALLKHLEGISDEDIINITLPTGVPILLELDENLRAVGPHQFLGDQEAIQAAIKKVEDQGKVKQAKK | carbohydrate derivative catabolic process carbohydrate metabolic process defense response to protozoan erythrocyte development establishment of blood-brain barrier glycolytic process neuroinflammatory response oxygen transport respiratory gaseous exchange by respiratory system cytosol; extracellular exosome 2,3-bisphos... |
adenine salvage AMP salvage GMP salvage grooming behavior IMP salvage purine ribonucleoside salvage | cytoplasm; cytosol; extracellular exosome; extracellular region; nucleoplasm; secretory granule lumen | adenine binding adenine phosphoribosyltransferase activity AMP binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Disease variant Glycosyltransferase Phosphoprotein Purine salvage Reference proteome Transferase | MADSELQLVE | MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE | adenine salvage AMP salvage GMP salvage grooming behavior IMP salvage purine ribonucleoside salvage cytoplasm; cytosol; extracellular exosome; extracellular region; nucleoplasm; secretory granule lumen adenine binding adenine phosphoribosyltransferase activity AMP binding Homo sapiens 3D-structure Acetylation Alternati... |
2'-deoxyribonucleotide biosynthetic process cell proliferation in forebrain deoxyribonucleotide biosynthetic process DNA repair DNA synthesis involved in DNA repair male gonad development mitochondrial DNA replication positive regulation of G0 to G1 transition positive regulation of G1/S transition of mitotic cell cycl... | cell projection; cytosol; mitochondrion; neuronal cell body; nuclear envelope; ribonucleoside-diphosphate reductase complex | ATP binding disordered domain specific binding identical protein binding purine nucleotide binding ribonucleoside-diphosphate reductase activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | Mus musculus | Acetylation Allosteric enzyme ATP-binding Cytoplasm Deoxyribonucleotide synthesis Disulfide bond Nucleotide-binding Oxidoreductase Phosphoprotein Reference proteome | MHVIKRDGRQ | MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGRHSPMVASSTLDIVMANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHKEDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIFEFLDLKKNTGK... | 2'-deoxyribonucleotide biosynthetic process cell proliferation in forebrain deoxyribonucleotide biosynthetic process DNA repair DNA synthesis involved in DNA repair male gonad development mitochondrial DNA replication positive regulation of G0 to G1 transition positive regulation of G1/S transition of mitotic cell cycl... |
cytoskeleton organization epithelial cell differentiation intermediate filament organization keratinization negative regulation of epithelial cell proliferation | cell surface; intermediate filament cytoskeleton; keratin filament | structural constituent of skin epidermis | Mus musculus | Coiled coil Direct protein sequencing Intermediate filament Keratin Methylation Reference proteome | MIARQSSVRG | MIARQSSVRGASRGFSSGSAIAGGVKRVAFSSGSMSGGAGRCSSGGFGSRSLYNLGGHKSISMSVAGSCQGGGYGGAGGFGVGGYGAGFGAGGFGGGFGGSFNGRGGPGFPVCPAGGIQEVTINQSLLTPLQVEIDPEIQKIRTAEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQTTTTSPKSLDPFFETYINALRKNLDTLSNDKGRLQSELKMMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYMIKVELEAKMESLKDEINFTRVLYEAELAQMQTHVSDTSVVLSMDNNRNLDLDGIIAEV... | cytoskeleton organization epithelial cell differentiation intermediate filament organization keratinization negative regulation of epithelial cell proliferation cell surface; intermediate filament cytoskeleton; keratin filament structural constituent of skin epidermis Mus musculus Coiled coil Direct protein sequencing ... |
photosynthetic electron transport in photosystem II response to herbicide | chloroplast thylakoid membrane; photosystem II | chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor oxygen evolving activity | Chlamydomonas reinhardtii | 3D-structure Acetylation Calcium Chlorophyll Chloroplast Chromophore Electron transport Herbicide resistance Iron Magnesium Manganese Membrane Metal-binding Oxidoreductase Phosphoprotein Photosynthesis Photosystem II Plastid Reference proteome Thylakoid Transmembrane Transmembrane helix Transport | MTAILERREN | MTAILERRENSSLWARFCEWITSTENRLYIGWFGVIMIPCLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIITGAVIPTSNAIGLHFYPIWEAASLDEWLYNGGPYQLIVCHFLLGVYCYMGREWELSFRLGMRPWIAVAYSAPVAAASAVFLVYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGLSTMAFNLNGFNFNQSVVDSQGRVLNTWADI... | photosynthetic electron transport in photosystem II response to herbicide chloroplast thylakoid membrane; photosystem II chlorophyll binding electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity iron ion binding oxidoreductase activity, acting on diphenols ... |
acute-phase response protein N-linked glycosylation response to chromate response to cytokine response to lead ion response to methanol response to peptide hormone | collagen-containing extracellular matrix; endoplasmic reticulum; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bounded organelle | endopeptidase inhibitor activity identical protein binding protease binding serine-type endopeptidase inhibitor activity | Mus musculus | Acute phase Glycoprotein Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal | MTPSISWGLL | MTPSISWGLLLLAGLCCLVPSFLAEDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTSEADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIAEAVKKLDQDTVFALANYILFKGKWKKPFDPENTEEAEFHVDESTTVKVPMMTLSGMLHVHHCSTLSSWVLLMDYAGNATAVFLLPDDGKMQHLEQTLSKELISKFLLNRRRRLAQIHFPRLSISGEYNLKTL... | acute-phase response protein N-linked glycosylation response to chromate response to cytokine response to lead ion response to methanol response to peptide hormone collagen-containing extracellular matrix; endoplasmic reticulum; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bounded ... |
response to cytokine response to peptide hormone | collagen-containing extracellular matrix; extracellular space | serine-type endopeptidase inhibitor activity | Mus musculus | Direct protein sequencing Glycoprotein Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal | MAFIVAMGMI | MAFIVAMGMILMAGICPAVLCFPDGTKEMDIVFHEHQDNGTQDDSLTLASVNTDFAFSLYKKLALKNPDTNIVFSPLSISAALALVSLGAKGKTMEEILEGLKFNLTETPEADIHQGFGNLLQSLSQPEDQDQINIGNAMFIEKDLQILAEFHEKTRALYQTEAFTADFQQPTEAKNLINDYVSNQTQGMIKELISELDERTLMVLVNYIYFKGKWKISFDPQDTFESEFYLDEKRSVKVPMMKMKLLTTRHFRDEELSCSVLELKYTGNASALLILPDQGRMQQVEASLQPETLRKWRKTLFPSQIEELNLPKFSIASN... | response to cytokine response to peptide hormone collagen-containing extracellular matrix; extracellular space serine-type endopeptidase inhibitor activity Mus musculus Direct protein sequencing Glycoprotein Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal MAFIVAMGMI MAFIVAMGMILMAGICPAVLC... |
fructose 1,6-bisphosphate metabolic process glucose homeostasis glycolytic process mesoderm development | cytosol; M band; Z disc | fructose-bisphosphate aldolase activity | Drosophila melanogaster | 3D-structure Acetylation Alternative splicing Direct protein sequencing Glycolysis Lyase Reference proteome Schiff base | MTTYFNYPSK | MTTYFNYPSKELQDELREIAQKIVAPGKGILAADESGPTMGKRLQDIGVENTEDNRRAYRQLLFSTDPKLAENISGVILFHETLYQKADDGTPFAEILKKKGIILGIKVDKGVVPLFGSEDEVTTQGLDDLAARCAQYKKDGCDFAKWRCVLKIGKNTPSYQSILENANVLARYASICQSQRIVPIVEPEVLPDGDHDLDRAQKVTETVLAAVYKALSDHHVYLEGTLLKPNMVTAGQSAKKNTPEEIALATVQALRRTVPAAVTGVTFLSGGQSEEEATVNLSAINNVPLIRPWALTFSYGRALQASVLRAWAGKKENI... | fructose 1,6-bisphosphate metabolic process glucose homeostasis glycolytic process mesoderm development cytosol; M band; Z disc fructose-bisphosphate aldolase activity Drosophila melanogaster 3D-structure Acetylation Alternative splicing Direct protein sequencing Glycolysis Lyase Reference proteome Schiff base MTTYFNYP... |
sporulation resulting in formation of a cellular spore | outer membrane-bounded periplasmic space | copper ion binding oxidoreductase activity | Bacillus subtilis | 3D-structure Copper Metal-binding Oxidoreductase Reference proteome Repeat Sporulation | MTLEKFVDAL | MTLEKFVDALPIPDTLKPVQQSKEKTYYEVTMEECTHQLHRDLPPTRLWGYNGLFPGPTIEVKRNENVYVKWMNNLPSTHFLPIDHTIHHSDSQHEEPEVKTVVHLHGGVTPDDSDGYPEAWFSKDFEQTGPYFKREVYHYPNQQRGAILWYHDHAMALTRLNVYAGLVGAYIIHDPKEKRLKLPSDEYDVPLLITDRTINEDGSLFYPSAPENPSPSLPNPSIVPAFCGETILVNGKVWPYLEVEPRKYRFRVINASNTRTYNLSLDNGGDFIQIGSDGGLLPRSVKLNSFSLAPAERYDIIIDFTAYEGESIILANSA... | sporulation resulting in formation of a cellular spore outer membrane-bounded periplasmic space copper ion binding oxidoreductase activity Bacillus subtilis 3D-structure Copper Metal-binding Oxidoreductase Reference proteome Repeat Sporulation MTLEKFVDAL MTLEKFVDALPIPDTLKPVQQSKEKTYYEVTMEECTHQLHRDLPPTRLWGYNGLFPGPTIEVKRN... |
chromosome segregation DNA replication DNA topological change mitotic chromosome condensation | chromatin; cytosol; nucleolus; nucleus | DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity | Schizosaccharomyces pombe | DNA-binding Isomerase Phosphoprotein Reference proteome Topoisomerase | MSSSDSDSVS | MSSSDSDSVSLSIRRRQRRGSSKRISMKESDEESDSSENHPLSESLNKKSKSESDEDDIPIRKRRASSKKNMSNSSSKKRAKVMGNGGLKNGKKTAVVKEEEDFNEIAKPSPKHKRVSKANGSKNGAKSAVKKEESDTDDSVPLRAVSTVSLTPYKSELPSGASTTQNRSPNDEEDEDEDYKWWTSENIDDTQKWTTLEHNGVIFAPPYEPLPKNVKLIYDGNPVNLPPEAEEVAGFYAAMLETDHAKNPVFQDNFFRDFLKVCDECNFNHNIKEFSKCDFTQMFHHFEQKREEKKSMPKEQKKAIKQKKDEEEEKYKWC... | chromosome segregation DNA replication DNA topological change mitotic chromosome condensation chromatin; cytosol; nucleolus; nucleus DNA binding DNA topoisomerase type I (single strand cut, ATP-independent) activity Schizosaccharomyces pombe DNA-binding Isomerase Phosphoprotein Reference proteome Topoisomerase MSSSDSD... |
archaeal or bacterial-type flagellum-dependent cell motility chemotaxis regulation of chemotaxis | bacterial-type flagellum; cytoplasm | phosphoprotein phosphatase activity | Salmonella typhimurium | 3D-structure Chemotaxis Cytoplasm Flagellar rotation Hydrolase Protein phosphatase Reference proteome | MMQPSIKPAD | MMQPSIKPADEGSAGDIIARIGSLTRMLRDSLRELGLDQAIAEAAEAIPDARDRLDYVVQMTAQAAERALNSVEASQPHQDAMEKEAKALTQRWDEWFDNPIELSDARELVTDTRQFLRDVPGHTSFTNAQLLDIMMAQDFQDLTGQVIKRMMDVIQEIERQLLMVLLENIPEQSARPKRENESLLNGPQVDTSKAGVVASQDQVDDLLDSLGF | archaeal or bacterial-type flagellum-dependent cell motility chemotaxis regulation of chemotaxis bacterial-type flagellum; cytoplasm phosphoprotein phosphatase activity Salmonella typhimurium 3D-structure Chemotaxis Cytoplasm Flagellar rotation Hydrolase Protein phosphatase Reference proteome MMQPSIKPAD MMQPSIKPADEGSAG... |
regulation of meiotic cell cycle process involved in oocyte maturation regulation of protein phosphorylation | cAMP-dependent protein kinase complex; cytoplasm; cytosol; plasma membrane | cAMP binding cAMP-dependent protein kinase regulator activity | Sus scrofa | Acetylation cAMP cAMP-binding Cell membrane Direct protein sequencing Disulfide bond Membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat | MASGSTASEE | MASGSTASEEERSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKASARADSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGNDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPS... | regulation of meiotic cell cycle process involved in oocyte maturation regulation of protein phosphorylation cAMP-dependent protein kinase complex; cytoplasm; cytosol; plasma membrane cAMP binding cAMP-dependent protein kinase regulator activity Sus scrofa Acetylation cAMP cAMP-binding Cell membrane Direct protein sequ... |
adult feeding behavior central nervous system neuron development cerebral cortex development chemical synaptic transmission feeding behavior monocyte activation negative regulation of acute inflammatory response to antigenic stimulus negative regulation of blood pressure neuron projection development neuropeptide signa... | cytoplasm; extracellular space; GABA-ergic synapse; neuronal dense core vesicle; perikaryon; perinuclear region of cytoplasm; synapse; terminal bouton | G protein-coupled receptor binding neuropeptide hormone activity neuropeptide Y receptor binding | Rattus norvegicus | Amidation Cleavage on pair of basic residues Cytoplasmic vesicle Direct protein sequencing Neuropeptide Phosphoprotein Reference proteome Secreted Signal | MMLGNKRMGL | MMLGNKRMGLCGLTLALSLLVCLGILAEGYPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRYGKRSSPETLISDLLMRESTENAPRTRLEDPSMW | adult feeding behavior central nervous system neuron development cerebral cortex development chemical synaptic transmission feeding behavior monocyte activation negative regulation of acute inflammatory response to antigenic stimulus negative regulation of blood pressure neuron projection development neuropeptide signa... |
glandular epithelial cell maturation intracellular steroid hormone receptor signaling pathway lung alveolus development negative regulation of gene expression ovulation from ovarian follicle paracrine signaling progesterone receptor signaling pathway regulation of epithelial cell proliferation regulation of transcripti... | chromatin; cytosol; nuclear matrix; nucleus; plasma membrane; protein-DNA complex; receptor complex | ATPase binding chromatin DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific enzyme binding estrogen response element binding Hsp70 protein binding Hsp90 protein binding identical protein binding nuclear receptor activity nuclear steroid receptor activity steroid hormone binding transcr... | Gallus gallus | Alternative splicing Cytoplasm Direct protein sequencing DNA-binding Isopeptide bond Lipid-binding Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Steroid-binding Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MTEVKSKETR | MTEVKSKETRAPSSARDGAVLLQAPPSRGEAEGIDVALDGLLYPRSSDEEEEEEENEEEEEEEEPQQREEEEEEEEEDRDCPSYRPGGGSLSKDCLDSVLDTFLAPAAHAAPWSLFGPEVPEVPVAPMSRGPEQKAVDAGPGAPGPSQPRPGAPLWPGADSLNVAVKARPGPEDASENRAPGLPGAEERGFPERDAGPGEGGLAPAAAASPAAVEPGAGQDYLHVPILPLNSAFLASRTRQLLDVEAAYDGSAFGPRSSPSVPAADLAEYGYPPPDGKEGPFAYGEFQSALKIKEEGVGLPAAPPPFLGAKAAPADFAQP... | glandular epithelial cell maturation intracellular steroid hormone receptor signaling pathway lung alveolus development negative regulation of gene expression ovulation from ovarian follicle paracrine signaling progesterone receptor signaling pathway regulation of epithelial cell proliferation regulation of transcripti... |
iron ion import across plasma membrane | ATP-binding cassette (ABC) transporter complex; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; plasma membrane | ABC-type ferric hydroxamate transporter activity ATP binding ATP hydrolysis activity ferric iron transmembrane transporter activity | Escherichia coli | 3D-structure ATP-binding Cell inner membrane Cell membrane Ion transport Iron Iron transport Membrane Nucleotide-binding Reference proteome Translocase Transport | MQEYTNHSDT | MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY | iron ion import across plasma membrane ATP-binding cassette (ABC) transporter complex; ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; plasma membrane ABC-type ferric hydroxamate transporter activity ATP binding ATP hydrolysis activity ferric iron transmembrane transporter activity... |
maintenance of protein localization in endoplasmic reticulum negative regulation of IRE1-mediated unfolded protein response negative regulation of protein-containing complex assembly positive regulation of cell migration post-translational protein targeting to membrane, translocation | cell surface; cytoplasm; cytosol; endoplasmic reticulum lumen; intracellular membrane-bounded organelle; melanosome; mitochondrion | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone protein domain specific binding | Mesocricetus auratus | Acetylation ATP-binding Chaperone Cytoplasm Endoplasmic reticulum Hydrolase Isopeptide bond Methylation Nitration Nucleotide-binding Phosphoprotein Reference proteome Signal Ubl conjugation | MKFPMVAAAL | MKFPMVAAALLLLCAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSE... | maintenance of protein localization in endoplasmic reticulum negative regulation of IRE1-mediated unfolded protein response negative regulation of protein-containing complex assembly positive regulation of cell migration post-translational protein targeting to membrane, translocation cell surface; cytoplasm; cytosol; e... |
cellular response to organic substance endocytosis regulation of long-term neuronal synaptic plasticity regulation of neuronal synaptic plasticity regulation of opioid receptor signaling pathway regulation of short-term neuronal synaptic plasticity regulation of synaptic vesicle exocytosis response to amyloid-beta syna... | excitatory synapse; membrane; neuromuscular junction; neuron projection; neuron projection terminus; neuron spine; perinuclear region of cytoplasm; postsynaptic density; presynapse; presynaptic active zone; presynaptic membrane; protein-containing complex; Schaffer collateral - CA1 synapse; synapse; synaptic vesicle; s... | cholesterol binding identical protein binding protein domain specific binding protein-containing complex binding SH2 domain binding SNARE binding syntaxin-1 binding | Rattus norvegicus | Calcium Cytoplasmic vesicle Direct protein sequencing Glycoprotein Membrane Phosphoprotein Reference proteome Repeat Synapse Synaptosome Transmembrane Transmembrane helix Ubl conjugation | MDVVNQLVAG | MDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYTGELRLSVECANKTESALNIEVEFEYPFRLHQVYFDAPSCVKGGTTKIFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMMDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPMCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFMRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPASGGGGYGPQGDYGQQGYGQQGAPTSFSNQM | cellular response to organic substance endocytosis regulation of long-term neuronal synaptic plasticity regulation of neuronal synaptic plasticity regulation of opioid receptor signaling pathway regulation of short-term neuronal synaptic plasticity regulation of synaptic vesicle exocytosis response to amyloid-beta syna... |
cell morphogenesis phagocytosis plasma membrane repair response to cAMP | actin cytoskeleton; cell cortex; cell leading edge; cell pole; cell-cell junction; cortical actin cytoskeleton; early phagosome; intranuclear rod; lamellipodium; phagocytic cup; phagocytic vesicle; phagolysosome | ATP binding hydrolase activity myosin binding structural constituent of cytoskeleton | Dictyostelium discoideum | ATP-binding Cytoplasm Cytoskeleton Hydrolase Nucleotide-binding Reference proteome | MESEDVQALV | MESEDVQALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRYTGVMVGMGQKDSYIGDEAQSRKGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVSHTVPIYEGYSLPHAILRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLAYVALDFEAELQTAASSSALEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYSNVVLSGGSTMFPGIADRMNKELTA... | cell morphogenesis phagocytosis plasma membrane repair response to cAMP actin cytoskeleton; cell cortex; cell leading edge; cell pole; cell-cell junction; cortical actin cytoskeleton; early phagosome; intranuclear rod; lamellipodium; phagocytic cup; phagocytic vesicle; phagolysosome ATP binding hydrolase activity myosi... |
cell morphogenesis chemotaxis endocytosis hyperosmotic response mitotic cytokinesis phagocytosis phototaxis plasma membrane repair response to cAMP vesicle-mediated transport | actin cytoskeleton; actin filament; cell cortex; cell leading edge; cell pole; cell-cell junction; cortical actin cytoskeleton; early phagosome; endocytic vesicle; intranuclear rod; lamellipodium; leading edge of lamellipodium; lipid droplet; macropinocytic cup; phagocytic cup; phagocytic vesicle; phagolysosome; pseudo... | ATP binding hydrolase activity myosin binding structural constituent of cytoskeleton | Dictyostelium discoideum | 3D-structure ATP-binding Cytoplasm Cytoskeleton Direct protein sequencing Hydrolase Nucleotide-binding Phosphoprotein Reference proteome | MDGEDVQALV | MDGEDVQALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLAYVALDFEAEMQTAASSSALEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYGNVVLSGGTTMFPGIADRMNKELTA... | cell morphogenesis chemotaxis endocytosis hyperosmotic response mitotic cytokinesis phagocytosis phototaxis plasma membrane repair response to cAMP vesicle-mediated transport actin cytoskeleton; actin filament; cell cortex; cell leading edge; cell pole; cell-cell junction; cortical actin cytoskeleton; early phagosome; ... |
cell division endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle meiotic cell cycle protein ubiq... | 90S preribosome; nuclear matrix; nuclear SCF ubiquitin ligase complex; nucleolus; nucleus; SCF ubiquitin ligase complex | phosphoserine residue binding U3 snoRNA binding ubiquitin binding | Saccharomyces cerevisiae | 3D-structure Cell cycle Cell division Mitosis Nucleus Phosphoprotein Reference proteome Repeat Sporulation Ubl conjugation pathway WD repeat | MGSFPLAEFP | MGSFPLAEFPLRDIPVPYSYRVSGGIASSGSVTALVTAAGTHRNSSTAKTVETEDGEEDIDEYQRKRAAGSGESTPERSDFKRVKHDNHKTLHPVNLQNTGAASVDNDGLHNLTDISNDAEKLLMSVDDGSAAPSTLSVNMGVASHNVAAPTTVNAATITGSDVSNNVNSATINNPMEEGALPLSPTASSPGTTTPLAKTTKTINNNNNIADLIESKDSIISPEYLSDEIFSAINNNLPHAYFKNLLFRLVANMDRSELSDLGTLIKDNLKRDLITSLPFEISLKIFNYLQFEDIINSLGVSQNWNKIIRKSTSLWKKLL... | cell division endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle meiotic cell cycle protein ubiq... |
cytolysis in another organism monoatomic cation transport pore complex assembly | extracellular region; nematocyst; other organism cell membrane; pore complex | channel activity identical protein binding toxin activity | Stichodactyla helianthus | 3D-structure Cytolysis Direct protein sequencing Ion transport Membrane Nematocyst Secreted Target cell membrane Target membrane Toxin Transmembrane Transport | ALAGTIIAGA | ALAGTIIAGASLTFQVLDKVLEELGKVSRKIAVGIDNESGGTWTALNAYFRSGTTDVILPEFVPNTKALLYSGRKDTGPVATGAVAAFAYYMSSGNTLGVMFSVPFDYNWYSNWWDVKIYSGKRRADQGMYEDLYYGNPYRGDNGWHEKNLGYGLRMKGIMTSAGEAKMQIKISR | cytolysis in another organism monoatomic cation transport pore complex assembly extracellular region; nematocyst; other organism cell membrane; pore complex channel activity identical protein binding toxin activity Stichodactyla helianthus 3D-structure Cytolysis Direct protein sequencing Ion transport Membrane Nematoc... |
flagellated sperm motility fructose biosynthetic process sorbitol catabolic process | mitochondrial membrane; motile cilium; protein-containing complex | D-xylulose reductase activity L-iditol 2-dehydrogenase activity NAD binding zinc ion binding | Ovis aries | 3D-structure Cell projection Cilium Direct protein sequencing Flagellum Membrane Metal-binding Mitochondrion NAD Oxidoreductase Phosphoprotein Reference proteome Zinc | AKPAAENLSL | AKPAAENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQGRIGDFVVKKPMVLGHEASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNLSPTIFFCATPPDDGNLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEGLLGSKPEVTIECTGVETSIQAGIYATHSGGTLVLVGLGSEMTSVPLVHAATREVDIKGVFRYCNTWPMAISMLASKSVNVKPLVT... | flagellated sperm motility fructose biosynthetic process sorbitol catabolic process mitochondrial membrane; motile cilium; protein-containing complex D-xylulose reductase activity L-iditol 2-dehydrogenase activity NAD binding zinc ion binding Ovis aries 3D-structure Cell projection Cilium Direct protein sequencing Flag... |
bile acid metabolic process fatty acid beta-oxidation intracellular cholesterol transport lipid hydroperoxide transport positive regulation of intracellular cholesterol transport regulation of phospholipid biosynthetic process | cytoplasm; endoplasmic reticulum; mitochondrion; peroxisomal matrix; peroxisome | acetyl-CoA C-acyltransferase activity acetyl-CoA C-myristoyltransferase activity cholesterol transfer activity lipid binding phosphatidylcholine transfer activity propanoyl-CoA C-acyltransferase activity propionyl-CoA C2-trimethyltridecanoyltransferase activity | Bos taurus | Acetylation Acyltransferase Alternative initiation Cytoplasm Direct protein sequencing Endoplasmic reticulum Lipid metabolism Lipid transport Lipid-binding Mitochondrion Peroxisome Phosphoprotein Reference proteome Transferase Transport | MSLVASQSPL | MSLVASQSPLRNRVFVVGVGMTKFTKPGVENRDYPDLAKEAGQKALADAQIPYSAVEQACIGYVYGDSTSGQRAIYHSLGLTGIPIINVNNNCSTGSTALFMARQLIQGGLADCVLALGFEKMVKGPIAVNIQDKANPIDKHIEVMVNKYGLSPSPVAPQMFGNAGKEHMEKYGTTLEHFAKIGWKNHKHSVNNPYSQFQKEYSLDEVMTSRKIFDFLTVLQCCPTSDGAAAAILASEAFVQKHNLKPKAVEILAQEMVTDMPSSFEGKSIIKMVGFDMSKEAARRCYEKSGLRPSDIDVIELHDCFSANELITYEALGL... | bile acid metabolic process fatty acid beta-oxidation intracellular cholesterol transport lipid hydroperoxide transport positive regulation of intracellular cholesterol transport regulation of phospholipid biosynthetic process cytoplasm; endoplasmic reticulum; mitochondrion; peroxisomal matrix; peroxisome acetyl-CoA C-... |
cellular response to thyroid hormone stimulus collagen catabolic process decidualization epithelial cell differentiation proteolysis proteolysis involved in protein catabolic process regulation of apoptotic process thyroid hormone generation viral entry into host cell | apical plasma membrane; collagen-containing extracellular matrix; endolysosome lumen; external side of plasma membrane; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; lysosome; melanosome; peptidase inhibitor complex; perinuclear region of cytoplasm | collagen binding cysteine-type endopeptidase activity cysteine-type peptidase activity peptidase activity proteoglycan binding | Homo sapiens | 3D-structure Acetylation Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Membrane Protease Reference proteome Secreted Signal Thiol protease Zymogen | MWQLWASLCC | MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCG... | cellular response to thyroid hormone stimulus collagen catabolic process decidualization epithelial cell differentiation proteolysis proteolysis involved in protein catabolic process regulation of apoptotic process thyroid hormone generation viral entry into host cell apical plasma membrane; collagen-containing extrace... |
amyloid-beta clearance amyloid-beta clearance by cellular catabolic process amyloid-beta metabolic process bradykinin catabolic process cellular response to cytokine stimulus cellular response to UV-A cellular response to UV-B creatinine metabolic process hormone catabolic process kidney development learning or memory ... | axon; brush border; cytoplasm; cytoplasmic vesicle; dendrite; early endosome; membrane; membrane raft; neuron projection terminus; neuronal cell body; plasma membrane; presynapse; synapse; synaptic vesicle; trans-Golgi network | cardiolipin binding endopeptidase activity exopeptidase activity metalloendopeptidase activity oligopeptidase activity peptidase activity peptide binding phosphatidylserine binding protein homodimerization activity zinc ion binding | Rattus norvegicus | Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipoprotein Membrane Metal-binding Metalloprotease Myristate Phosphoprotein Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix Zinc | MGRSESQMDI | MGRSESQMDITDINAPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDASAEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEPKTEDIVAVQKAKTLYRSCINESAIDSRGGQPLLTLLPDIYGWPVASQNWEQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNSTQHIIHFDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEQRLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEINGKP... | amyloid-beta clearance amyloid-beta clearance by cellular catabolic process amyloid-beta metabolic process bradykinin catabolic process cellular response to cytokine stimulus cellular response to UV-A cellular response to UV-B creatinine metabolic process hormone catabolic process kidney development learning or memory ... |
cell wall organization peptidoglycan biosynthetic process regulation of cell shape | cytosol | ATP binding D-alanine-D-alanine ligase activity metal ion binding protein homodimerization activity | Escherichia coli | 3D-structure ATP-binding Cell shape Cell wall biogenesis/degradation Cytoplasm Direct protein sequencing Ligase Magnesium Manganese Metal-binding Nucleotide-binding Peptidoglycan synthesis Reference proteome | MTDKIAVLLG | MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAENALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD | cell wall organization peptidoglycan biosynthetic process regulation of cell shape cytosol ATP binding D-alanine-D-alanine ligase activity metal ion binding protein homodimerization activity Escherichia coli 3D-structure ATP-binding Cell shape Cell wall biogenesis/degradation Cytoplasm Direct protein sequencing Ligase ... |
ATP biosynthetic process flagellated sperm motility lactate biosynthetic process from pyruvate lactate metabolic process lactate oxidation pyruvate catabolic process pyruvate metabolic process | cytosol; extracellular exosome; mitochondrion; motile cilium; nucleus; oxidoreductase complex | L-lactate dehydrogenase activity | Homo sapiens | 3D-structure Cytoplasm NAD Oxidoreductase Phosphoprotein Reference proteome | MSTVKEQLIE | MSTVKEQLIEKLIEDDENSQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLKGEMMDLQHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIVHYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAYEIIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGVSDVVKINLNSEEEALFKKSA... | ATP biosynthetic process flagellated sperm motility lactate biosynthetic process from pyruvate lactate metabolic process lactate oxidation pyruvate catabolic process pyruvate metabolic process cytosol; extracellular exosome; mitochondrion; motile cilium; nucleus; oxidoreductase complex L-lactate dehydrogenase activity ... |
fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA oxidase phenylacetate catabolic process | peroxisome | acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acyltransferase activity acetyl-CoA C-myristoyltransferase activity | Rattus norvegicus | Acetylation Acyltransferase Fatty acid metabolism Lipid metabolism Peroxisome Reference proteome Transferase Transit peptide | MHRLQVVLGH | MHRLQVVLGHLAGRSESSSALQAAPCSAGFPQASASDVVVVHGRRTPIGRAGRGGFKDTTPDELLSAVLTAVLQDVKLKPECLGDISVGNVLQPGAGAAMARIAQFLSGIPETVPLSAVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMTLSERGNPGNISSRLLENEKARDCLIPMGITSENVAERFGISRQKQDAFALASQQKAASAQSKGCFRAEIVPVTTTVLDDKGDRKTITVSQDEGVRPSTTMEGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIG... | fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA oxidase phenylacetate catabolic process peroxisome acetyl-CoA C-acetyltransferase activity acetyl-CoA C-acyltransferase activity acetyl-CoA C-myristoyltransferase activity Rattus norvegicus Acetylation Acyltransferase Fatty acid metabolism Lipid metabol... |
fatty acid beta-oxidation using acyl-CoA oxidase fatty acid catabolic process fatty acid oxidation generation of precursor metabolites and energy hydrogen peroxide biosynthetic process lipid homeostasis lipid metabolic process prostaglandin metabolic process spermatogenesis very long-chain fatty acid beta-oxidation ver... | cytoplasm; peroxisomal matrix; peroxisomal membrane; peroxisome | acyl-CoA oxidase activity FAD binding fatty acid binding flavin adenine dinucleotide binding palmitoyl-CoA oxidase activity PDZ domain binding protein homodimerization activity | Rattus norvegicus | 3D-structure Acetylation Alternative splicing Direct protein sequencing FAD Fatty acid metabolism Flavoprotein Lipid metabolism Oxidoreductase Peroxisome Phosphoprotein Reference proteome | MNPDLRKERA | MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEIMWFKKLYLANFVEPVGLNYSMFIPTLLNQGTTAQQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQ... | fatty acid beta-oxidation using acyl-CoA oxidase fatty acid catabolic process fatty acid oxidation generation of precursor metabolites and energy hydrogen peroxide biosynthetic process lipid homeostasis lipid metabolic process prostaglandin metabolic process spermatogenesis very long-chain fatty acid beta-oxidation ver... |
ceramide catabolic process intestinal cholesterol absorption pancreatic juice secretion | cytoplasm; endoplasmic reticulum; extracellular space; Golgi apparatus; protein-containing complex; zymogen granule | acetylesterase activity glycosphingolipid binding lysophospholipase activity protein-containing complex binding retinyl-palmitate esterase activity sterol esterase activity triglyceride lipase activity | Rattus norvegicus | Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Reference proteome Repeat Secreted Serine esterase Signal | MGRLEVLFLG | MGRLEVLFLGLTCCLAAACAAKLGAVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFATAKTLENPQRHPGWQGTLKATDFKKRCLQATITQDDTYGQEDCLYLNIWVPQGRKQVSHDLPVMVWIYGGAFLMGSGQGANFLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGGDPDNITIFGESAGAASVSLQTLSPYNKGLIRRAISQSGVALSPWAIQENPLFWAKTIAKKVGCPTEDTAKMAGCLKITDPRALTLAYRLPLKSQEYPIVHYLAFIPVVDGDFIPDDP... | ceramide catabolic process intestinal cholesterol absorption pancreatic juice secretion cytoplasm; endoplasmic reticulum; extracellular space; Golgi apparatus; protein-containing complex; zymogen granule acetylesterase activity glycosphingolipid binding lysophospholipase activity protein-containing complex binding reti... |
tRNA modification | cytosol; mitochondrion; nucleolus; nucleus | ATP binding metal ion binding tRNA binding tRNA dimethylallyltransferase activity | Saccharomyces cerevisiae | 3D-structure Alternative initiation Amyloid ATP-binding Cytoplasm Metal-binding Mitochondrion Nucleotide-binding Nucleus Prion Reference proteome Transferase tRNA processing Zinc Zinc-finger | MLKGPLKGCL | MLKGPLKGCLNMSKKVIVIAGTTGVGKSQLSIQLAQKFNGEVINSDSMQVYKDIPIITNKHPLQEREGIPHHVMNHVDWSEEYYSHRFETECMNAIEDIHRRGKIPIVVGGTHYYLQTLFNKRVDTKSSERKLTRKQLDILESTDPDVIYNTLVKCDPDIATKYHPNDYRRVQRMLEIYYKTGKKPSETFNEQKITLKFDTLFLWLYSKPEPLFQRLDDRVDDMLERGALQEIKQLYEYYSQNKFTPEQCENGVWQVIGFKEFLPWLTGKTDDNTVKLEDCIERMKTRTRQYAKRQVKWIKKMLIPDIKGDIYLLDATDL... | tRNA modification cytosol; mitochondrion; nucleolus; nucleus ATP binding metal ion binding tRNA binding tRNA dimethylallyltransferase activity Saccharomyces cerevisiae 3D-structure Alternative initiation Amyloid ATP-binding Cytoplasm Metal-binding Mitochondrion Nucleotide-binding Nucleus Prion Reference proteome Trans... |
fatty acid beta-oxidation | cytosol; peroxisome | 3-hydroxyacyl-CoA dehydrogenase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity enzyme binding intramolecular oxidoreductase activity, transposing C=C bonds long-chain-3-hydroxyacyl-CoA dehydrogenase activity NAD+ binding | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing Fatty acid metabolism Isomerase Lipid metabolism Lyase Multifunctional enzyme NAD Oxidoreductase Peroxisome Phosphoprotein Reference proteome | MAEYLRLPHS | MAEYLRLPHSLAMIRLCNPPVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFSAFTPGLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPVEEAIKFAQKIIDKPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQASVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGI... | fatty acid beta-oxidation cytosol; peroxisome 3-hydroxyacyl-CoA dehydrogenase activity delta(3)-delta(2)-enoyl-CoA isomerase activity enoyl-CoA hydratase activity enzyme binding intramolecular oxidoreductase activity, transposing C=C bonds long-chain-3-hydroxyacyl-CoA dehydrogenase activity NAD+ binding Rattus norvegic... |
galactose catabolic process galactose catabolic process via UDP-galactose galactose metabolic process UDP-glucose metabolic process | cytoplasm; cytosol; Golgi apparatus | UDP-glucose:hexose-1-phosphate uridylyltransferase activity zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Carbohydrate metabolism Cataract Disease variant Galactose metabolism Metal-binding Nucleotidyltransferase Reference proteome Transferase Zinc | MSRSGTDPQQ | MSRSGTDPQQRQQASEADAAAATFRANDHQHIRYNPLQDEWVLVSAHRMKRPWQGQVEPQLLKTVPRHDPLNPLCPGAIRANGEVNPQYDSTFLFDNDFPALQPDAPSPGPSDHPLFQAKSARGVCKVMCFHPWSDVTLPLMSVPEIRAVVDAWASVTEELGAQYPWVQIFENKGAMMGCSNPHPHCQVWASSFLPDIAQREERSQQAYKSQHGEPLLMEYSRQELLRKERLVLTSEHWLVLVPFWATWPYQTLLLPRRHVRRLPELTPAERDDLASIMKKLLTKYDNLFETSFPYSMGWHGAPTGSEAGANWNHWQLHA... | galactose catabolic process galactose catabolic process via UDP-galactose galactose metabolic process UDP-glucose metabolic process cytoplasm; cytosol; Golgi apparatus UDP-glucose:hexose-1-phosphate uridylyltransferase activity zinc ion binding Homo sapiens 3D-structure Alternative splicing Carbohydrate metabolism Cata... |
compound eye morphogenesis female germ-line stem cell population maintenance negative regulation of RNA splicing oogenesis positive regulation of mRNA splicing, via spliceosome positive regulation of translation regulation of alternative mRNA splicing, via spliceosome | nucleus; polytene chromosome puff; ribonucleoprotein complex | mRNA 3'-UTR binding mRNA 5'-UTR binding mRNA binding poly(G) binding sequence-specific DNA binding | Drosophila melanogaster | Alternative splicing Nucleus Reference proteome Repeat Ribonucleoprotein RNA-binding | MVNSNQNQNG | MVNSNQNQNGNSNGHDDDFPQDSITEPEHMRKLFIGGLDYRTTDENLKAHFEKWGNIVDVVVMKDPRTKRSRGFGFITYSHSSMIDEAQKSRPHKIDGRVVEPKRAVPRQDIDSPNAGATVKKLFVGALKDDHDEQSIRDYFQHFGNIVDINIVIDKETGKKRGFAFVEFDDYDPVDKVVLQKQHQLNGKMVDVKKALPKQNDQQGGGGGRGGPGGRAGGNRGNMGGGNYGNQNGGGNWNNGGNNWGNNRGGNDNWGNNSFGGGGGGGGGYGGGNNSWGNNNPWDNGNGGGNFGGGGNNWNNGGNDFGGYQQNYGGGPQR... | compound eye morphogenesis female germ-line stem cell population maintenance negative regulation of RNA splicing oogenesis positive regulation of mRNA splicing, via spliceosome positive regulation of translation regulation of alternative mRNA splicing, via spliceosome nucleus; polytene chromosome puff; ribonucleoprotei... |
3'-UTR-mediated mRNA stabilization chromatin remodeling mRNA splicing, via spliceosome negative regulation of telomere maintenance via telomerase osteoblast differentiation RNA splicing | actin cytoskeleton; catalytic step 2 spliceosome; chromatin; cytosol; extracellular exosome; extracellular region; membrane; nucleoplasm; nucleus; protein-containing complex; spliceosomal complex; telomerase holoenzyme complex | identical protein binding mRNA 3'-UTR binding N6-methyladenosine-containing RNA reader activity nucleosomal DNA binding poly(U) RNA binding RNA binding telomerase RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Coiled coil Direct protein sequencing Isopeptide bond mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding Spliceosome Ubl conjugation | MASNVTNKTD | MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSKSGKLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQSSSSVKKDETNVKMESEGGADDSAEEGDLLDDDDNEDRGDDQLELIKDDEKEAEEGEDDRDSANGEDDS | 3'-UTR-mediated mRNA stabilization chromatin remodeling mRNA splicing, via spliceosome negative regulation of telomere maintenance via telomerase osteoblast differentiation RNA splicing actin cytoskeleton; catalytic step 2 spliceosome; chromatin; cytosol; extracellular exosome; extracellular region; membrane; nucleopla... |
L-serine biosynthetic process L-threonine catabolic process to glycine threonine catabolic process | cytoplasm; cytosol | cadmium ion binding ferrous iron binding L-threonine 3-dehydrogenase activity manganese ion binding oxidoreductase activity zinc ion binding | Escherichia coli | Cobalt Cytoplasm Direct protein sequencing Metal-binding NAD Oxidoreductase Reference proteome Zinc | MKALSKLKAE | MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLAAIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDD... | L-serine biosynthetic process L-threonine catabolic process to glycine threonine catabolic process cytoplasm; cytosol cadmium ion binding ferrous iron binding L-threonine 3-dehydrogenase activity manganese ion binding oxidoreductase activity zinc ion binding Escherichia coli Cobalt Cytoplasm Direct protein sequencing M... |
aerobic respiration cellular respiration mitochondrial electron transport, ubiquinol to cytochrome c oxidative phosphorylation | mitochondrial inner membrane; mitochondrial respirasome; mitochondrial respiratory chain complex III; mitochondrion | ubiquinol-cytochrome-c reductase activity | Homo sapiens | 3D-structure Acetylation Disulfide bond Electron transport Membrane Mitochondrion Mitochondrion inner membrane Primary mitochondrial disease Reference proteome Respiratory chain Transit peptide Transport | MGLEDEQKML | MGLEDEQKMLTESGDPEEEEEEEEELVDPLTTVREQCEQLEKCVKARERLELCDERVSSRSHTEEDCTEELFDFLHARDHCVAHKLFNNLK | aerobic respiration cellular respiration mitochondrial electron transport, ubiquinol to cytochrome c oxidative phosphorylation mitochondrial inner membrane; mitochondrial respirasome; mitochondrial respiratory chain complex III; mitochondrion ubiquinol-cytochrome-c reductase activity Homo sapiens 3D-structure Acetylati... |
proton motive force-driven ATP synthesis | mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) | lipid binding proton transmembrane transporter activity | Bos taurus | 3D-structure CF(0) Direct protein sequencing Hydrogen ion transport Ion transport Lipid-binding Membrane Methylation Mitochondrion Reference proteome Transit peptide Transmembrane Transmembrane helix Transport | MYTCAKFVST | MYTCAKFVSTPSLIRRTSTVLSRSLSAVVVRRPETLTDESHSSLAVVPRPLTTSLTPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM | proton motive force-driven ATP synthesis mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) lipid binding proton transmembrane transporter activity Bos taurus 3D-structure CF(0) Direct protein sequencing Hydrogen ion transport Ion transpo... |
glycogen biosynthetic process glycogen catabolic process glycogen metabolic process phosphorylation | phosphorylase kinase complex | ATP binding calmodulin binding enzyme binding phosphorylase kinase activity protein serine kinase activity tau-protein kinase activity | Mus musculus | ATP-binding Calmodulin-binding Carbohydrate metabolism Glycogen metabolism Kinase Muscle protein Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase | MTRDDALPDS | MTRDDALPDSHSAQTFYENYEPKEILGRGVSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLTEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLQPGEKLREVCGTPSYLAPEIIQCSMDDGHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMDGKYQFGSPEWDDYSDTVKDLVSRFLVVQPQDRCSAEEALAHPFFQEYVVEEVRHFSPRGKFKVICLTVLASVKIYY... | glycogen biosynthetic process glycogen catabolic process glycogen metabolic process phosphorylation phosphorylase kinase complex ATP binding calmodulin binding enzyme binding phosphorylase kinase activity protein serine kinase activity tau-protein kinase activity Mus musculus ATP-binding Calmodulin-binding Carbohydrate... |
astrocyte differentiation axon choice point recognition axon guidance axon regeneration cell fate commitment nervous system development radial glial cell differentiation regulation of filopodium assembly regulation of growth regulation of postsynaptic specialization assembly tissue regeneration | axon; cell periphery; cytoplasm; dendrite; filopodium membrane; GABA-ergic synapse; growth cone; growth cone membrane; perikaryon; plasma membrane; postsynaptic density; presynapse | calmodulin binding lysophosphatidic acid binding phosphatidylinositol phosphate binding phosphatidylserine binding | Rattus norvegicus | Calmodulin-binding Cell membrane Cell projection Cytoplasm Developmental protein Differentiation Direct protein sequencing Growth regulation Lipoprotein Membrane Neurogenesis Palmitate Phosphoprotein Reference proteome Synapse | MLCCMRRTKQ | MLCCMRRTKQVEKNDEDQKIEQDGVKPEDKAHKAATKIQASFRGHITRKKLKDEKKGDAPAAEAEAKEKDDAPVADGVEKKEGDGSATTDAAPATSPKAEEPSKAGDAPSEEKKGEGDAAPSEEKAGSAETESAAKATTDNSPSSKAEDGPAKEEPKQADVPAAVTDAAATTPAAEDAAKAAQPPTETAESSQAEEEKEAVDEAKPKESARQDEGKEDPEADQEHA | astrocyte differentiation axon choice point recognition axon guidance axon regeneration cell fate commitment nervous system development radial glial cell differentiation regulation of filopodium assembly regulation of growth regulation of postsynaptic specialization assembly tissue regeneration axon; cell periphery; cy... |
cellular hyperosmotic salinity response cellular response to methylglyoxal cellular response to peptide daunorubicin metabolic process doxorubicin metabolic process epithelial cell maturation fructose biosynthetic process inner medullary collecting duct development L-ascorbic acid biosynthetic process maternal process ... | cytosol; extracellular space; mast cell granule; paranodal junction; perinuclear region of cytoplasm; plasma membrane bounded cell projection cytoplasm; Schmidt-Lanterman incisure; Schwann cell microvillus | alditol:NADP+ 1-oxidoreductase activity allyl-alcohol dehydrogenase activity cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity glyceraldehyde oxidoreductase activity glycerol dehydrogenase activity L-glucuronate reductase activity NADP-retinol dehydrogenase activity prostaglandin H2 endoperoxidase reduct... | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing Lipid metabolism NADP Oxidoreductase Phosphoprotein Reference proteome | MASHLELNNG | MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCALMSCAKHKDYPFHAEV | cellular hyperosmotic salinity response cellular response to methylglyoxal cellular response to peptide daunorubicin metabolic process doxorubicin metabolic process epithelial cell maturation fructose biosynthetic process inner medullary collecting duct development L-ascorbic acid biosynthetic process maternal process ... |
cell differentiation cellular response to platelet-derived growth factor stimulus cellular response to retinoic acid cellular response to transforming growth factor beta stimulus ephrin receptor signaling pathway Fc-gamma receptor signaling pathway involved in phagocytosis innate immune response leukocyte migration neg... | actin filament; centrosome; cytosol; extracellular exosome; extrinsic component of cytoplasmic side of plasma membrane; focal adhesion; Golgi apparatus; plasma membrane | ATP binding enzyme binding non-membrane spanning protein tyrosine kinase activity phosphotyrosine residue binding protein tyrosine kinase activity signaling receptor binding transmembrane transporter binding | Homo sapiens | 3D-structure ATP-binding Cell membrane Cytoplasm Cytoskeleton Kinase Lipoprotein Membrane Myristate Nucleotide-binding Palmitate Phosphoprotein Proto-oncogene Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase | MGCIKSKENK | MGCIKSKENKSPAIKYRPENTPEPVSTSVSHYGAEPTTVSPCPSSSAKGTAVNFSSLSMTPFGGSSGVTPFGGASSSFSVVPSSYPAGLTGGVTIFVALYDYEARTTEDLSFKKGERFQIINNTEGDWWEARSIATGKNGYIPSNYVAPADSIQAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYKIRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPTVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTKVAIKTLKPGTMMPEAFLQE... | cell differentiation cellular response to platelet-derived growth factor stimulus cellular response to retinoic acid cellular response to transforming growth factor beta stimulus ephrin receptor signaling pathway Fc-gamma receptor signaling pathway involved in phagocytosis innate immune response leukocyte migration neg... |
actin filament organization muscle contraction regulation of ATP-dependent activity | actin cytoskeleton; actin filament; cytosol; muscle thin filament tropomyosin | actin binding actin filament binding identical protein binding protein heterodimerization activity protein homodimerization activity structural constituent of muscle | Homo sapiens | Acetylation Actin-binding Alternative splicing Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Disease variant Muscle protein Nemaline myopathy Phosphoprotein Reference proteome | MDAIKKKMQM | MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL | actin filament organization muscle contraction regulation of ATP-dependent activity actin cytoskeleton; actin filament; cytosol; muscle thin filament tropomyosin actin binding actin filament binding identical protein binding protein heterodimerization activity protein homodimerization activity structural constituent of... |
animal organ regeneration carbohydrate phosphorylation fructose 2,6-bisphosphate metabolic process fructose metabolic process negative regulation of glycolytic process through fructose-6-phosphate response to cAMP response to glucagon response to glucocorticoid response to insulin response to starvation | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex; cytosol | 6-phosphofructo-2-kinase activity ATP binding fructose-2,6-bisphosphate 2-phosphatase activity fructose-6-phosphate binding identical protein binding kinase binding | Rattus norvegicus | 3D-structure Acetylation Alternative splicing ATP-binding Direct protein sequencing Hydrolase Kinase Multifunctional enzyme Nucleotide-binding Phosphoprotein Reference proteome Transferase | MSREMGELTQ | MSREMGELTQTRLQKIWIPHSSSSSVLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYRNYEFFRPDNTEAQLIRKQCALAALKDVHKYLSREEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPEIIAENIKQVKLGSPDYIDCDQEKVLEDFLKRIECYEINYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHVQSRTAYYLMNIHVTPRSIYLCRHGESELNLRGRIGGDSGLSARGKQYAYALANFIRSQGISSLKVWTSHMKRTIQTAEALGVPY... | animal organ regeneration carbohydrate phosphorylation fructose 2,6-bisphosphate metabolic process fructose metabolic process negative regulation of glycolytic process through fructose-6-phosphate response to cAMP response to glucagon response to glucocorticoid response to insulin response to starvation 6-phosphofructo... |
DNA damage response DNA repair fumarate metabolic process homeostasis of number of cells within a tissue malate metabolic process positive regulation of cold-induced thermogenesis positive regulation of double-strand break repair via nonhomologous end joining regulation of arginine metabolic process tricarboxylic acid ... | chromosome; cytoplasm; cytosol; extracellular exosome; mitochondrial matrix; mitochondrion; nucleus; site of double-strand break; tricarboxylic acid cycle enzyme complex | fumarate hydratase activity histone binding | Homo sapiens | 3D-structure Acetylation Alternative initiation Chromosome Cytoplasm Direct protein sequencing Disease variant DNA damage DNA repair Lyase Mitochondrion Nucleus Phosphoprotein Reference proteome Transit peptide Tricarboxylic acid cycle Tumor suppressor | MYRALRLLAR | MYRALRLLARSRPLVRAPAAALASAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDA... | DNA damage response DNA repair fumarate metabolic process homeostasis of number of cells within a tissue malate metabolic process positive regulation of cold-induced thermogenesis positive regulation of double-strand break repair via nonhomologous end joining regulation of arginine metabolic process tricarboxylic acid ... |
endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | host cell surface receptor binding sialate 4-O-acetylesterase activity sialate 9-O-acetylesterase activity | Influenza C virus | 3D-structure Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Hemagglutinin Host cell membrane Host membrane Host-virus interaction Hydrolase Membrane Reference proteome Signal Transmembrane Transmembrane helix Viral attachment to host cell Vi... | MFFSLLLVLG | MFFSLLLVLGLTEAEKIKICLQKQVNSSFSLHNGFGGNLYATEEKRMFELVKPKAGASVLNQSTWIGFGDSRTDKSNSAFPRSADVSAKTADKFRFLSGGSLMLSMFGPPGKVDYLYQGCGKHKVFYEGVNWSPHAAINCYRKNWTDIKLNFQKNIYELASQSHCMSLVNALDKTIPLQVTAGTAGNCNNSFLKNPALYTQEVKPSENKCGKENLAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCDNYFQVIYDSFGKVVGGLDNRVSPYTGNSGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPERSYCFDMK... | endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane viral budding from plasma membrane virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane host cell surface receptor bin... |
chromosome condensation nucleus organization spermatid development spermatogenesis | male germ cell nucleus; nucleoplasm; nucleosome; nucleus | cadmium ion binding DNA binding zinc ion binding | Mus musculus | Chromosome Developmental protein Differentiation Direct protein sequencing DNA condensation DNA-binding Nucleosome core Nucleus Phosphoprotein Reference proteome Spermatogenesis | MVRYRMRSPS | MVRYRMRSPSEGPHQGPGQDHEREEQGQGQGLSPERVEDYGRTHRGHHHHRHRRCSRKRLHRIHKRRRSCRRRRRHSCRHRRRHRRGCRRSRRRRRCRCRKCRRHHH | chromosome condensation nucleus organization spermatid development spermatogenesis male germ cell nucleus; nucleoplasm; nucleosome; nucleus cadmium ion binding DNA binding zinc ion binding Mus musculus Chromosome Developmental protein Differentiation Direct protein sequencing DNA condensation DNA-binding Nucleosome cor... |
cellulose catabolic process | extracellular region | cellulase activity cellulose binding | Hypocrea jecorina | 3D-structure Carbohydrate metabolism Cellulose degradation Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal | MAPSVTLPLT | MAPSVTLPLTTAILAIARLVAAQQPGTSTPEVHPKLTTYKCTKSGGCVAQDTSVVLDWNYRWMHDANYNSCTVNGGVNTTLCPDEATCGKNCFIEGVDYAASGVTTSGSSLTMNQYMPSSSGGYSSVSPRLYLLDSDGEYVMLKLNGQELSFDVDLSALPCGENGSLYLSQMDENGGANQYNTAGANYGSGYCDAQCPVQTWRNGTLNTSHQGFCCNEMDILEGNSRANALTPHSCTATACDSAGCGFNPYGSGYKSYYGPGDTVDTSKTFTIITQFNTDNGSPSGNLVSITRKYQQNGVDIPSAQPGGDTISSCPSASA... | cellulose catabolic process extracellular region cellulase activity cellulose binding Hypocrea jecorina 3D-structure Carbohydrate metabolism Cellulose degradation Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal MAPSVTLPLT... |
cellulose catabolic process | extracellular region | cellulase activity cellulose binding | Hypocrea jecorina | 3D-structure Carbohydrate metabolism Cellulose degradation Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal | MNKSVAPLLL | MNKSVAPLLLAASILYGGAVAQQTVWGQCGGIGWSGPTNCAPGSACSTLNPYYAQCIPGATTITTSTRPPSGPTTTTRATSTSSSTPPTSSGVRFAGVNIAGFDFGCTTDGTCVTSKVYPPLKNFTGSNNYPDGIGQMQHFVNEDGMTIFRLPVGWQYLVNNNLGGNLDSTSISKYDQLVQGCLSLGAYCIVDIHNYARWNGGIIGQGGPTNAQFTSLWSQLASKYASQSRVWFGIMNEPHDVNINTWAATVQEVVTAIRNAGATSQFISLPGNDWQSAGAFISDGSAAALSQVTNPDGSTTNLIFDVHKYLDSDNSGTH... | cellulose catabolic process extracellular region cellulase activity cellulose binding Hypocrea jecorina 3D-structure Carbohydrate metabolism Cellulose degradation Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal MNKSVAPLLL... |
cellulose catabolic process | extracellular region | cellulose 1,4-beta-cellobiosidase activity cellulose binding identical protein binding | Hypocrea jecorina | 3D-structure Carbohydrate metabolism Cellulose degradation Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Pyrrolidone carboxylic acid Secreted Signal | MIVGILTTLA | MIVGILTTLATLATLAASVPLEERQACSSVWGQCGGQNWSGPTCCASGSTCVYSNDYYSQCLPGAASSSSSTRAASTTSRVSPTTSRSSSATPPPGSTTTRVPPVGSGTATYSGNPFVGVTPWANAYYASEVSSLAIPSLTGAMATAAAAVAKVPSFMWLDTLDKTPLMEQTLADIRTANKNGGNYAGQFVVYDLPDRDCAALASNGEYSIADGGVAKYKNYIDTIRQIVVEYSDIRTLLVIEPDSLANLVTNLGTPKCANAQSAYLECINYAVTQLNLPNVAMYLDAGHAGWLGWPANQDPAAQLFANVYKNASSPRAL... | cellulose catabolic process extracellular region cellulose 1,4-beta-cellobiosidase activity cellulose binding identical protein binding Hypocrea jecorina 3D-structure Carbohydrate metabolism Cellulose degradation Direct protein sequencing Disulfide bond Glycoprotein Glycosidase Hydrolase Polysaccharide degradation Pyrr... |
arginine catabolic process to glutamate arginine catabolic process to proline via ornithine L-proline biosynthetic process ornithine metabolic process | cytoplasm; cytosol; nucleus | identical protein binding ornithine aminotransferase activity pyridoxal phosphate binding | Saccharomyces cerevisiae | Aminotransferase Cytoplasm Isopeptide bond Pyridoxal phosphate Reference proteome Transferase Ubl conjugation | MSEATLSSKQ | MSEATLSSKQTIEWENKYSAHNYHPLPVVFHKAKGAHVWDPEGKLYLDFLSAYSAVNQGHCHPHIIKALTEQAQTLTLSSRAFHNDVYAQFAKFVTEFFGFETVLPMNTGAEAVETALKLARRWGYMKKNIPQDKAIILGAEGNFHGRTFGAISLSTDYEDSKLHFGPFVPNVASGHSVHKIRYGHAEDFVPILESPEGKNVAAIILEPIQGEAGIVVPPADYFPKVSALCRKHNVLLIVDEIQTGIGRTGELLCYDHYKAEAKPDIVLLGKALSGGVLPVSCVLSSHDIMSCFTPGSHGSTFGGNPLASRVAIAALEVI... | arginine catabolic process to glutamate arginine catabolic process to proline via ornithine L-proline biosynthetic process ornithine metabolic process cytoplasm; cytosol; nucleus identical protein binding ornithine aminotransferase activity pyridoxal phosphate binding Saccharomyces cerevisiae Aminotransferase Cytoplas... |
hemoglobin biosynthetic process regulation of cell cycle regulation of cell population proliferation | extracellular space; inhibin A complex; inhibin-betaglycan-ActRII complex | cytokine activity growth factor activity hormone activity | Bos taurus | Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Growth factor Hormone Reference proteome Secreted Signal | MWLQLLLLLL | MWLQLLLLLLAPQGGHGCHGLELDRELVLAKVRALFLDALGPPPVTGEGGDPGVRRLHRRHAVGGFMRRGSEPEDQDVSQAILFPAAGASCGDEPDAGEAEEGLFTYVFQPSQHTRSRQVTSAQLWFHTGLDRQETAAANSSEPLLGLLVLTSGGPMPVPMSLGQAPPRWAVLHLATSAFPLLTHPVLALLLRCPLCSCSTRPEATPFLVAHTRAKPPSGGERARRSTPPLPWPWSPAALRLLQRPPEEPAAHADCHRAALNISFQELGWDRWIVHPPSFIFYYCHGGCGLSPPQDLPLPVPGVPPTPVQPLSLVPGAQP... | hemoglobin biosynthetic process regulation of cell cycle regulation of cell population proliferation extracellular space; inhibin A complex; inhibin-betaglycan-ActRII complex cytokine activity growth factor activity hormone activity Bos taurus Cleavage on pair of basic residues Direct protein sequencing Disulfide bond ... |
erythrocyte development heme biosynthetic process hemoglobin biosynthetic process protoporphyrinogen IX biosynthetic process response to bile acid | cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrion | 5-aminolevulinate synthase activity pyridoxal phosphate binding | Gallus gallus | Acyltransferase Direct protein sequencing Heme biosynthesis Hydroxylation Membrane Mitochondrion Mitochondrion inner membrane Pyridoxal phosphate Reference proteome Transferase Transit peptide | MEAVVRRCPF | MEAVVRRCPFLARVSQAFLQKAGPSLLFYAQHCPKMMEAAPPAAARGLATSASRGQQVEETPAAQPEAKKAKEVAQQNTDGSQPPAGHPPAAAVQSSATKCPFLAAQMNHKSSNVFCKASLELQEDVKEMQVDRKGKEFAKIPTNSVVRNTEAEGEEQSGLLKKFKDIMLKQRPESVSHLLQDNLPKSVSTFQYDQFFEKKIDEKKKDHTYRVFKTVNRKAQIFPMADDYSDSLITKKEVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLEKELADLHGKDAALLFSSCFVANDSTLFTLAK... | erythrocyte development heme biosynthetic process hemoglobin biosynthetic process protoporphyrinogen IX biosynthetic process response to bile acid cytosol; mitochondrial inner membrane; mitochondrial matrix; mitochondrion 5-aminolevulinate synthase activity pyridoxal phosphate binding Gallus gallus Acyltransferase Dire... |
defense response to Gram-positive bacterium | extracellular exosome | lyase activity nucleic acid binding ribonuclease A activity RNA nuclease activity | Homo sapiens | 3D-structure Direct protein sequencing Disulfide bond Endonuclease Glycoprotein Hydrolase Lyase Nuclease Reference proteome Secreted Signal | MALEKSLVRL | MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST | defense response to Gram-positive bacterium extracellular exosome lyase activity nucleic acid binding ribonuclease A activity RNA nuclease activity Homo sapiens 3D-structure Direct protein sequencing Disulfide bond Endonuclease Glycoprotein Hydrolase Lyase Nuclease Reference proteome Secreted Signal MALEKSLVRL MALEKSLV... |
acrosome reaction activation of adenylate cyclase activity proteolysis single fertilization | acrosomal matrix; protein-containing complex | amidase activity fucose binding mannose binding serine-type endopeptidase activity serine-type peptidase activity | Sus scrofa | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MLPTAVLLVL | MLPTAVLLVLAVSVAARDNATCDGPCGLRFRQKLESGMRVVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRLIFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVGCARAKRPGVYTSTWPYLNWIASKIGSNALQMVQLGTPPRPSTPAPPVRPPSVQTPVR... | acrosome reaction activation of adenylate cyclase activity proteolysis single fertilization acrosomal matrix; protein-containing complex amidase activity fucose binding mannose binding serine-type endopeptidase activity serine-type peptidase activity Sus scrofa 3D-structure Direct protein sequencing Disulfide bond Glyc... |
blood coagulation, fibrin clot formation chaperone-mediated protein folding platelet aggregation positive regulation of protein folding protein folding response to endoplasmic reticulum stress | cell surface; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; extracellular space; melanosome; smooth endoplasmic reticulum | integrin binding protein disulfide isomerase activity protein-disulfide reductase activity | Mus musculus | 3D-structure Acetylation Disulfide bond Endoplasmic reticulum Glycoprotein Isomerase Redox-active center Reference proteome Repeat Signal | MKLRKAWLLV | MKLRKAWLLVLLLALTQLLAAASAGDAHEDTSDTENATEEEEEEDDDDLEVKEENGVWVLNDGNFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIASTLKDNDPPIAVAKIDATSASMLASKFDVSGYPTIKILKKGQAVDYDGSRTQEEIVAKVREVSQPDWTPPPEVTLSLTKDNFDDVVNNADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATEQTDLAKRFDVSGYPTLKIFRKGRPFDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGDDVVIIGLFQGDGDPAYLQYQDAA... | blood coagulation, fibrin clot formation chaperone-mediated protein folding platelet aggregation positive regulation of protein folding protein folding response to endoplasmic reticulum stress cell surface; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; extracellular space;... |
cellular detoxification of nitrogen compound cellular response to caffeine glutathione metabolic process hepoxilin biosynthetic process linoleic acid metabolic process nitrobenzene metabolic process regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum xenobiotic catabolic process | cytosol; intercellular bridge; sarcoplasmic reticulum | enzyme binding fatty acid binding glutathione binding glutathione peroxidase activity glutathione transferase activity protein homodimerization activity signaling receptor binding | Rattus norvegicus | Cytoplasm Direct protein sequencing Reference proteome Transferase | MPMTLGYWDI | MPMTLGYWDIRGLAHAIRLLLEYTDSSYEEKRYTMGDAPDFDRSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNPDFEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEATCLDAFPNLKDFIARFEGLKKISDYMKSSRFLPRPLFTKMAIWGSK | cellular detoxification of nitrogen compound cellular response to caffeine glutathione metabolic process hepoxilin biosynthetic process linoleic acid metabolic process nitrobenzene metabolic process regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum xenobiotic catabolic process cyto... |
cellular detoxification of nitrogen compound cellular response to caffeine glutathione metabolic process hepoxilin biosynthetic process linoleic acid metabolic process nitrobenzene metabolic process regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum response to catechin response to ... | cytoplasm; cytosol; protein-containing complex; sarcoplasmic reticulum | enzyme binding fatty acid binding glutathione binding glutathione peroxidase activity glutathione transferase activity identical protein binding protein homodimerization activity signaling receptor binding | Rattus norvegicus | 3D-structure Cytoplasm Direct protein sequencing Lipid metabolism Olfaction Phosphoprotein Reference proteome Sensory transduction Transferase | MPMTLGYWDI | MPMTLGYWDIRGLAHAIRLFLEYTDTSYEDKKYSMGDAPDYDRSQWLSEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDFERKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQHRIFEPKCLDAFPNLKDFVARFEGLKKISDYMKSGRFLSKPIFAKMAFWNPK | cellular detoxification of nitrogen compound cellular response to caffeine glutathione metabolic process hepoxilin biosynthetic process linoleic acid metabolic process nitrobenzene metabolic process regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum response to catechin response to ... |
cellular response to lipid hydroperoxide glutathione metabolic process glutathione transport Leydig cell differentiation response to lipopolysaccharide response to organonitrogen compound response to xenobiotic stimulus | apical part of cell; endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion; peroxisomal membrane | glutathione binding glutathione peroxidase activity glutathione transferase activity identical protein binding | Rattus norvegicus | 3D-structure Acetylation Direct protein sequencing Endoplasmic reticulum Membrane Mitochondrion Mitochondrion outer membrane Nitration Reference proteome Transferase Transmembrane Transmembrane helix | MADLKQLMDN | MADLKQLMDNEVLMAFTSYATIILAKMMFLSSATAFQRLTNKVFANPEDCAGFGKGENAKKFLRTDEKVERVRRAHLNDLENIVPFLGIGLLYSLSGPDLSTALIHFRIFVGARIYHTIAYLTPLPQPNRGLAFFVGYGVTLSMAYRLLRSRLYL | cellular response to lipid hydroperoxide glutathione metabolic process glutathione transport Leydig cell differentiation response to lipopolysaccharide response to organonitrogen compound response to xenobiotic stimulus apical part of cell; endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial ... |
actin filament organization cellular hyperosmotic response hyperosmotic response MAPK cascade osmosensory signaling pathway protein import into nucleus protein phosphorylation response to antibiotic | cellular bud neck; cellular bud tip; cytoplasm; cytoplasmic stress granule; NatB complex | ATP binding MAP kinase kinase activity MAP-kinase scaffold activity peptide alpha-N-acetyltransferase activity protein kinase activity protein serine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity | Saccharomyces cerevisiae | 3D-structure Antibiotic resistance ATP-binding Cytoplasm Kinase Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase Tyrosine-protein kinase | MEDKFANLSL | MEDKFANLSLHEKTGKSSIQLNEQTGSDNGSAVKRTSSTSSHYNNINADLHARVKAFQEQRALKRSASVGSNQSEQDKGSSQSPKHIQQIVNKPLPPLPVAGSSKVSQRMSSQVVQASSKSTLKNVLDNQETQNITDVNINIDTTKITATTIGVNTGLPATDITPSVSNTASATHKAQLLNPNRRAPRRPLSTQHPTRPNVAPHKAPAIINTPKQSLSARRGLKLPPGGMSLKMPTKTAQQPQQFAPSPSNKKHIETLSNSKVVEGKRSNPGSLINGVQSTSTSSSTEGPHDTVGTTPRTGNSNNSSNSGSSGGGGLFAN... | actin filament organization cellular hyperosmotic response hyperosmotic response MAPK cascade osmosensory signaling pathway protein import into nucleus protein phosphorylation response to antibiotic cellular bud neck; cellular bud tip; cytoplasm; cytoplasmic stress granule; NatB complex ATP binding MAP kinase kinase ac... |
mesenchyme migration positive regulation of gene expression | cell body; cytoplasm; cytoskeleton; filopodium; lamellipodium | ATP binding hydrolase activity | Gallus gallus | Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Muscle protein Nucleotide-binding Oxidation Reference proteome | MCEEEDSTAL | MCEEEDSTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILSERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEIT... | mesenchyme migration positive regulation of gene expression cell body; cytoplasm; cytoskeleton; filopodium; lamellipodium ATP binding hydrolase activity Gallus gallus Acetylation ATP-binding Cytoplasm Cytoskeleton Hydrolase Methylation Muscle protein Nucleotide-binding Oxidation Reference proteome MCEEEDSTAL MCEEEDSTAL... |
adenine metabolic process adenine salvage AMP salvage GMP salvage grooming behavior IMP salvage lactation purine ribonucleoside salvage | cytoplasm; cytosol; nucleoplasm | adenine binding adenine phosphoribosyltransferase activity AMP binding | Mus musculus | Acetylation Cytoplasm Glycosyltransferase Phosphoprotein Purine salvage Reference proteome Transferase | MSEPELKLVA | MSEPELKLVARRIRSFPDFPIPGVLFRDISPLLKDPDSFRASIRLLASHLKSTHSGKIDYIAGLDSRGFLFGPSLAQELGVGCVLIRKQGKLPGPTVSASYSLEYGKAELEIQKDALEPGQRVVIVDDLLATGGTMFAACDLLHQLRAEVVECVSLVELTSLKGRERLGPIPFFSLLQYD | adenine metabolic process adenine salvage AMP salvage GMP salvage grooming behavior IMP salvage lactation purine ribonucleoside salvage cytoplasm; cytosol; nucleoplasm adenine binding adenine phosphoribosyltransferase activity AMP binding Mus musculus Acetylation Cytoplasm Glycosyltransferase Phosphoprotein Purine salv... |
cell-cell signaling epididymis development purine ribonucleotide transport | connexin complex; cytoplasm; gap junction; lateral plasma membrane; plasma membrane; protein-containing complex | gap junction channel activity identical protein binding | Rattus norvegicus | Cell junction Cell membrane Direct protein sequencing Gap junction Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MNWTGLYTLL | MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDHFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCEAFPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC | cell-cell signaling epididymis development purine ribonucleotide transport connexin complex; cytoplasm; gap junction; lateral plasma membrane; plasma membrane; protein-containing complex gap junction channel activity identical protein binding Rattus norvegicus Cell junction Cell membrane Direct protein sequencing Gap j... |
cell-cell signaling epididymis development gap junction assembly nervous system development purine ribonucleotide transport | connexin complex; endoplasmic reticulum membrane; lateral plasma membrane | gap junction channel activity identical protein binding | Homo sapiens | 3D-structure Cell junction Cell membrane Charcot-Marie-Tooth disease Dejerine-Sottas syndrome Disease variant Gap junction Membrane Neurodegeneration Neuropathy Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MNWTGLYTLL | MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLSPEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC | cell-cell signaling epididymis development gap junction assembly nervous system development purine ribonucleotide transport connexin complex; endoplasmic reticulum membrane; lateral plasma membrane gap junction channel activity identical protein binding Homo sapiens 3D-structure Cell junction Cell membrane Charcot-Mari... |
acute inflammatory response angiogenesis involved in wound healing binding of sperm to zona pellucida cell adhesion development of secondary sexual characteristics epithelial cell development epithelial cell proliferation extracellular matrix organization galactose metabolic process lactose biosynthetic process lipid m... | basolateral plasma membrane; brush border membrane; desmosome; external side of plasma membrane; extracellular space; filopodium; Golgi apparatus; Golgi cisterna membrane; Golgi trans cisterna; protein-containing complex | alpha-tubulin binding beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity beta-tubulin binding cytoskeletal protein binding identical protein binding lactose synthase activity manganese ion binding N-acetyllactosamine synthase activity UDP-galactosyltransferase activity | Bos taurus | 3D-structure Alternative initiation Cell membrane Cell projection Direct protein sequencing Disulfide bond Glycoprotein Glycosyltransferase Golgi apparatus Lipid metabolism Manganese Membrane Metal-binding Reference proteome Secreted Signal-anchor Transferase Transmembrane Transmembrane helix | MKFREPLLGG | MKFREPLLGGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLRRLPQLVGVHPPLQGSSHGAAAIGQPSGELRLRGVAPPPPLQNSSKPRSRAPSNLDAYSHPGPGPGPGSNLTSAPVPSTTTRSLTACPEESPLLVGPMLIEFNIPVDLKLVEQQNPKVKLGGRYTPMDCISPHKVAIIIPFRNRQEHLKYWLYYLHPILQRQQLDYGIYVINQAGESMFNRAKLLNVGFKEALKDYDYNCFVFSDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLSINGFPNNYWGWGGEDDD... | acute inflammatory response angiogenesis involved in wound healing binding of sperm to zona pellucida cell adhesion development of secondary sexual characteristics epithelial cell development epithelial cell proliferation extracellular matrix organization galactose metabolic process lactose biosynthetic process lipid m... |
asymmetric neuroblast division central nervous system development compound eye development ectoderm and mesoderm interaction gastrulation involving germ band extension Malpighian tubule morphogenesis mesoderm development negative regulation of DNA-templated transcription negative regulation of transcription by RNA poly... | nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding... | Drosophila melanogaster | Developmental protein DNA-binding Metal-binding Nucleus Reference proteome Repeat Zinc Zinc-finger | MAANYKSCPL | MAANYKSCPLKKRPIVFVEERLPQTEALALTKDSQFAQDQPQDLSLKRGRDEETQDYQQPEPKRDYVLNLSKTPERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTTINPFQSAFVMAAGCNPISALWSSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDLETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHAKNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIRTHTLPCKCPICGKAFSRPWL... | asymmetric neuroblast division central nervous system development compound eye development ectoderm and mesoderm interaction gastrulation involving germ band extension Malpighian tubule morphogenesis mesoderm development negative regulation of DNA-templated transcription negative regulation of transcription by RNA poly... |
cellular response to estrogen stimulus cellular response to insulin stimulus cellular response to wortmannin cellular response to zinc ion starvation positive regulation by host of viral transcription positive regulation of amyloid-beta formation positive regulation of angiogenesis positive regulation of blood vessel e... | chromatin; cytoplasm; euchromatin; nucleoplasm; nucleus; protein-DNA complex; transcription repressor complex | bHLH transcription factor binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific double-stranded DNA binding histone acetyltransferase binding histone deacetylase binding... | Homo sapiens | 3D-structure Acetylation Activator Alternative splicing Biological rhythms Cytoplasm Direct protein sequencing DNA-binding Glycoprotein Host-virus interaction Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Repressor Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MSDQDHSMDE | MSDQDHSMDEMTAVVKIEKGVGGNNGGNGNGGGAFSQARSSSTGSSSSTGGGGQESQPSPLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQLSQGANGWQIISSSSGATPTSKEQSGSSTNGSNGSESSKNRTVSGGQYVVAAAPNLQNQQVLTGLPGVMPNIQYQVIPQFQTVDGQQLQFAATGAQVQQDGSGQIQIIPGANQQIITNRGSGGNIIAAMPNLLQQAVPLQGLANNVLSGQTQYVTNVPVALNGNITLLPVNSVSAATLTPSSQAVTISSSGSQESGSQPVTSGTTISSASLVSSQASSSSF... | cellular response to estrogen stimulus cellular response to insulin stimulus cellular response to wortmannin cellular response to zinc ion starvation positive regulation by host of viral transcription positive regulation of amyloid-beta formation positive regulation of angiogenesis positive regulation of blood vessel e... |
positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | chromatin; nucleolus; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Homo sapiens | 3D-structure Activator Alternative splicing DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MDEDEFELQP | MDEDEFELQPQEPNSFFDGIGADATHMDGDQIVVEIQEAVFVSNIVDSDITVHNFVPDDPDSVVIQDVVEDVVIEEDVQCSDILEEADVSENVIIPEQVLDSDVTEEVSLPHCTVPDDVLASDITSTSMSMPEHVLTSESMHVCDIGHVEHMVHDSVVEAEIITDPLTSDIVSEEVLVADCAPEAVIDASGISVDQQDNDKASCEDYLMISLDDAGKIEHDGSTGVTIDAESEMDPCKVDSTCPEVIKVYIFKADPGEDDLGGTVDIVESEPENDHGVELLDQNSSIRVPREKMVYMTVNDSQQEDEDLNVAEIADEVYM... | positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II chromatin; nucleolus; nucleoplasm; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific metal ion binding RNA polym... |
amyloid-beta metabolic process bradykinin catabolic process cellular response to cytokine stimulus cellular response to UV-A cellular response to UV-B creatinine metabolic process hormone catabolic process kidney development peptide metabolic process proteolysis replicative senescence sensory perception of pain substan... | axon; brush border; cytoplasm; dendrite; neuron projection terminus; plasma membrane; synapse; synaptic vesicle | metalloendopeptidase activity peptide binding zinc ion binding | Oryctolagus cuniculus | 3D-structure Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipoprotein Membrane Metal-binding Metalloprotease Myristate Phosphoprotein Protease Reference proteome Signal-anchor Transmembrane Transmembrane helix Zinc | MGRSESQMDI | MGRSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTVIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATAEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEPKTEDIVAVQKAKTLYRSCVNETAIDSRGGQPLLKLLPDVYGWPVATQNWEQTYGTSWSAEKSIAQLNSNYGKKVLINFFVGTDDKNSMNHIIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMIAVAKLIRQEEGLPIDENQISVEMNKVMELEKEIANATTKSEDRNDPMLLYNKMTLAQIQNNFSLEINGKP... | amyloid-beta metabolic process bradykinin catabolic process cellular response to cytokine stimulus cellular response to UV-A cellular response to UV-B creatinine metabolic process hormone catabolic process kidney development peptide metabolic process proteolysis replicative senescence sensory perception of pain substan... |
cardiac muscle contraction skeletal muscle contraction | cardiac myofibril; cardiac Troponin complex; troponin complex | actin binding ATP binding ATPase inhibitor activity magnesium ion binding troponin C binding | Bos taurus | Acetylation Actin-binding Direct protein sequencing Muscle protein Phosphoprotein Reference proteome | MADRSGGSTA | MADRSGGSTAGDTVPAPPPVRRRSSANYRAYATEPHAKKKSKISASRKLQLKTLMLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLNQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKETLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKKFEG | cardiac muscle contraction skeletal muscle contraction cardiac myofibril; cardiac Troponin complex; troponin complex actin binding ATP binding ATPase inhibitor activity magnesium ion binding troponin C binding Bos taurus Acetylation Actin-binding Direct protein sequencing Muscle protein Phosphoprotein Reference proteom... |
erythrocyte homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glycolytic process in utero embryonic development mesoderm formation positive regulation of endothelial cell migration positive regulation of immunoglobulin production | ciliary membrane; cytosol; extracellular space | carbohydrate derivative binding cytokine activity glucose-6-phosphate isomerase activity monosaccharide binding ubiquitin protein ligase binding | Sus scrofa | 3D-structure Acetylation Cytokine Cytoplasm Direct protein sequencing Gluconeogenesis Glycolysis Hydroxylation Isomerase Phosphoprotein Reference proteome Secreted Ubl conjugation | MAALTQNPQF | MAALTQNPQFKKLQTWYHEHRSDLNLRRLFEGDKDRFNHFSLNLNTNHGRILLDYSKNLVTEAVMQMLVDLAKSRGVEAARERMFNGEKINFTEDRAVLHVALRNRSNTPILVDGKDVMPEVNRVLEKMKSFCKRVRSGEWKGYSGKSITDVINIGIGGSDLGPLMVTEALKPYSAEGPRVWFVSNIDGTHIAKTLATLNPESSLFIIASKTFTTQETITNAETAKEWFLQSAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLL... | erythrocyte homeostasis gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glycolytic process in utero embryonic development mesoderm formation positive regulation of endothelial cell migration positive regulation of immunoglobulin production ciliary membrane; cytosol; extracellular space carbohy... |
aerobic respiration cellular respiration mitochondrial electron transport, ubiquinol to cytochrome c | mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrion | 2 iron, 2 sulfur cluster binding metal ion binding oxidoreductase activity ubiquinol-cytochrome-c reductase activity | Saccharomyces cerevisiae | 2Fe-2S 3D-structure Direct protein sequencing Disulfide bond Electron transport Iron Iron-sulfur Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Reference proteome Respiratory chain Transit peptide Translocase Transmembrane Transmembrane helix Transport | MLGIRSSVKT | MLGIRSSVKTCFKPMSLTSKRLISQSLLASKSTYRTPNFDDVLKENNDADKGRSYAYFMVGAMGLLSSAGAKSTVETFISSMTATADVLAMAKVEVNLAAIPLGKNVVVKWQGKPVFIRHRTPHEIQEANSVDMSALKDPQTDADRVKDPQWLIMLGICTHLGCVPIGEAGDFGGWFCPCHGSHYDISGRIRKGPAPLNLEIPAYEFDGDKVIVG | aerobic respiration cellular respiration mitochondrial electron transport, ubiquinol to cytochrome c mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrion 2 iron, 2 sulfur cluster binding metal ion binding oxidoreductase activity ubiquinol-cytochrome-c reductase activity Saccharomyces... |
glucose metabolic process NADH oxidation xylulose metabolic process | mitochondrial matrix; mitochondrion | carbonyl reductase (NADPH) activity identical protein binding L-xylulose reductase (NADP+) activity protein self-association | Mus musculus | 3D-structure Direct protein sequencing Mitochondrion NAD NADP Oxidoreductase Phosphoprotein Reference proteome | MKLNFSGLRA | MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWDATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDAGYLAS | glucose metabolic process NADH oxidation xylulose metabolic process mitochondrial matrix; mitochondrion carbonyl reductase (NADPH) activity identical protein binding L-xylulose reductase (NADP+) activity protein self-association Mus musculus 3D-structure Direct protein sequencing Mitochondrion NAD NADP Oxidoreductase P... |
cell cycle cell division clathrin coat assembly clathrin-dependent endocytosis endocytosis intracellular protein transport | clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin complex; clathrin vesicle coat; clathrin-coated endocytic vesicle membrane; clathrin-coated pit; clathrin-coated vesicle; cytoplasmic vesicle; glutamatergic synapse; plasma membrane; postsynaptic endocytic zone; postsynap... | clathrin heavy chain binding GTPase binding peptide binding protein-containing complex binding structural molecule activity | Rattus norvegicus | Acetylation Alternative splicing Calcium Cell cycle Cell division Coated pit Cytoplasm Cytoplasmic vesicle Cytoskeleton Direct protein sequencing Membrane Mitosis Phosphoprotein Reference proteome | MAELDPFGAP | MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAPGPQAHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISEVDRLQSEPESIRKWREEQTERLEALDANSRKQEAEWKEKAVKELEEWYARQDEQLQKTKASNRVADEAFYKQPFADVIGYVTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH | cell cycle cell division clathrin coat assembly clathrin-dependent endocytosis endocytosis intracellular protein transport clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin complex; clathrin vesicle coat; clathrin-coated endocytic vesicle membrane; clathrin-coated pit; c... |
clathrin-dependent endocytosis intracellular protein transport neurotransmitter secretion neurotransmitter transport synaptic vesicle coating | ciliary membrane; clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin vesicle coat; cytosol; plasma membrane; postsynaptic endocytic zone cytoplasmic component; presynaptic endocytic zone membrane; synaptic vesicle membrane; trans-Golgi network | clathrin heavy chain binding neurotransmitter transmembrane transporter activity peptide binding structural molecule activity | Rattus norvegicus | Acetylation Alternative splicing Calcium Coated pit Cytoplasmic vesicle Direct protein sequencing Disulfide bond Membrane Phosphoprotein Reference proteome | MAEDFGFFSS | MAEDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDSGFGAPAASQVASAQPGLASGGGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR | clathrin-dependent endocytosis intracellular protein transport neurotransmitter secretion neurotransmitter transport synaptic vesicle coating ciliary membrane; clathrin coat; clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin vesicle coat; cytosol; plasma membrane; postsynaptic endocyti... |
cell cycle G1/S phase transition intracellular signal transduction meiotic cell cycle negative regulation of cell cycle switching, mitotic to meiotic cell cycle negative regulation of induction of conjugation with cellular fusion negative regulation of protein import into nucleus negative regulation of transcription by... | cytoplasm; cytosol; nucleus | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Schizosaccharomyces pombe | ATP-binding Conjugation Kinase Meiosis Nucleotide-binding Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MMRENPELLL | MMRENPELLLGQVLGDSLRFVSIIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQARELALHARVSSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQLISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLATTEPYSSDFGCGSLFYMSPECQREVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCCKRNPWKRACSQTDGTYRSYVHNPSTLLSILPISRELNSLLNRIFDRNPKTRITLPELSTLVSNCKNLTRRLRPAPLVSSRYLAYQQ... | cell cycle G1/S phase transition intracellular signal transduction meiotic cell cycle negative regulation of cell cycle switching, mitotic to meiotic cell cycle negative regulation of induction of conjugation with cellular fusion negative regulation of protein import into nucleus negative regulation of transcription by... |
G protein-coupled receptor signaling pathway phototransduction visual perception | membrane | G protein-coupled photoreceptor activity G protein-coupled receptor activity | Drosophila melanogaster | Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MERSHLPETP | MERSHLPETPFDLAHSGPRFQAQSSGNGSVLDNVLPDMAHLVNPYWSRFAPMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQSPVMIINFYYETWVLGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGINGTPMTIKTSIMKILFIWMMAVFWTVMPLIGWSAYVPEGNLTACSIDYMTRMWNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLRSSEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLFKIDGLTPLTTIW... | G protein-coupled receptor signaling pathway phototransduction visual perception membrane G protein-coupled photoreceptor activity G protein-coupled receptor activity Drosophila melanogaster Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Referen... |
absorption of visible light adaptation of rhodopsin mediated signaling cellular response to light stimulus detection of temperature stimulus involved in thermoception G protein-coupled receptor signaling pathway gene expression microtubule cytoskeleton organization photoreceptor cell maintenance phototransduction photo... | cell-cell junction; ciliary membrane; Golgi apparatus; Golgi membrane; Golgi-associated vesicle membrane; membrane; photoreceptor disc membrane; photoreceptor inner segment; photoreceptor inner segment membrane; photoreceptor outer segment; photoreceptor outer segment membrane; plasma membrane; rod photoreceptor outer ... | 11-cis retinal binding G protein-coupled photoreceptor activity G protein-coupled receptor activity metal ion binding | Homo sapiens | 3D-structure Acetylation Cell projection Chromophore Congenital stationary night blindness Disease variant Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Metal-binding Palmitate Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Retinitis pigmentosa Sensory tra... | MNGTEGPNFY | MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTT... | absorption of visible light adaptation of rhodopsin mediated signaling cellular response to light stimulus detection of temperature stimulus involved in thermoception G protein-coupled receptor signaling pathway gene expression microtubule cytoskeleton organization photoreceptor cell maintenance phototransduction photo... |
cell differentiation defense response to Gram-positive bacterium exocytosis inflammatory response innate immune response intracellular signal transduction localization negative regulation of apoptotic process peptidyl-tyrosine phosphorylation phagocytosis positive regulation of cell population proliferation protein aut... | caveola; cell projection; cytoplasmic side of plasma membrane; cytoskeleton; cytosol; extrinsic component of cytoplasmic side of plasma membrane; focal adhesion; Golgi apparatus; intracellular membrane-bounded organelle; lysosome; nucleus; plasma membrane; transport vesicle | ATP binding lipid binding non-membrane spanning protein tyrosine kinase activity phosphotyrosine residue binding protein tyrosine kinase activity signaling receptor binding | Mus musculus | Alternative initiation ATP-binding Cell junction Cell membrane Cell projection Cytoplasm Cytoplasmic vesicle Cytoskeleton Exocytosis Golgi apparatus Immunity Inflammatory response Innate immunity Kinase Lipoprotein Lysosome Membrane Myristate Nucleotide-binding Nucleus Palmitate Phagocytosis Phosphoprotein Proto-oncoge... | MGGRSSCEDP | MGGRSSCEDPGCPRSEGRAPRMGCVKSRFLRDGSKASKTEPSANQKGPVYVPDPTSSSKLGPNNSNSMPPGFVEGSEDTIVVALYDYEAIHREDLSFQKGDQMVVLEEAGEWWKARSLATKKEGYIPSNYVARVNSLETEEWFFKGISRKDAERHLLAPGNMLGSFMIRDSETTKGSYSLSVRDFDPQHGDTVKHYKIRTLDSGGFYISPRSTFSSLQELVLHYKKGKDGLCQKLSVPCVSPKPQKPWEKDAWEIPRESLQMEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANLMKSLQHDKLVKLHA... | cell differentiation defense response to Gram-positive bacterium exocytosis inflammatory response innate immune response intracellular signal transduction localization negative regulation of apoptotic process peptidyl-tyrosine phosphorylation phagocytosis positive regulation of cell population proliferation protein aut... |
chaperone cofactor-dependent protein refolding protein refolding response to cold response to heat response to organic cyclic compound response to organonitrogen compound response to progesterone | cytoplasm; cytosol; nucleus; perikaryon; plasma membrane; receptor complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone heat shock protein binding nuclear progesterone receptor binding protein folding chaperone | Gallus gallus | ATP-binding Nucleotide-binding Reference proteome Stress response | MSGKGPAIGI | MSGKGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKYDDPTVQSDMKHWPFRVVNEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGKKVETAVITVPAYFNDSQRQATKDAGTITGLNVMRIINEPTAAAIAYGLDKKGTRAGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNRFVEEFKGKHKRDNAGNKRAVRRLRTACERARRTLSSSTQASIEIDSLFEGIDFYTSITRARFEELNADLFRGTLEPV... | chaperone cofactor-dependent protein refolding protein refolding response to cold response to heat response to organic cyclic compound response to organonitrogen compound response to progesterone cytoplasm; cytosol; nucleus; perikaryon; plasma membrane; receptor complex ATP binding ATP hydrolysis activity ATP-dependent... |
intracellular sequestering of iron ion protein folding ubiquitin-dependent ERAD pathway | endoplasmic reticulum; melanosome; perinuclear region of cytoplasm; sarcoplasmic reticulum lumen | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone unfolded protein binding | Gallus gallus | ATP-binding Calcium Chaperone Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Nucleotide-binding Reference proteome Sarcoplasmic reticulum Signal Stress response | MKSAWALALA | MKSAWALALACTLLLAASVTAEEVDVDATVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIKEIREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNMLHVTDTGIGMTKEELIKNLGTIAKSGTSEFLNKMTEMQDDSQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFSVIDDPRGNTLGRGTTITLVLKEEASDYLELDTVKNLVKKYSQFINFPIYVWSSKTETVEEPVEEEEAKEEKEETDDNEAAVEEEEEEKKP... | intracellular sequestering of iron ion protein folding ubiquitin-dependent ERAD pathway endoplasmic reticulum; melanosome; perinuclear region of cytoplasm; sarcoplasmic reticulum lumen ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone unfolded protein binding Gallus gallus ATP-binding Calcium ... |
actin rod assembly cellular response to ATP insulin processing negative regulation of apoptotic process protein folding response to hypoxia retrograde protein transport, ER to cytosol ubiquitin-dependent ERAD pathway | cytosol; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; endoplasmic reticulum membrane; extracellular region; melanosome; midbody; perinuclear region of cytoplasm; protein-containing complex; sarcoplasmic reticulum lumen; smooth endoplasmic reticulum; sperm plasma membrane | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone low-density lipoprotein particle receptor binding protein folding chaperone protein phosphatase binding RNA binding unfolded protein binding | Mus musculus | Acetylation ATP-binding Calcium Chaperone Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Hydroxylation Nucleotide-binding Phosphoprotein Reference proteome Sarcoplasmic reticulum Signal | MRVLWVLGLC | MRVLWVLGLCCVLLTFGFVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSSKTETVEEPLEEDEAAKEEKEESDDEAAVEEEEEEKK... | actin rod assembly cellular response to ATP insulin processing negative regulation of apoptotic process protein folding response to hypoxia retrograde protein transport, ER to cytosol ubiquitin-dependent ERAD pathway cytosol; endoplasmic reticulum; endoplasmic reticulum chaperone complex; endoplasmic reticulum lumen; e... |
collagen and cuticulin-based cuticle development cuticle development involved in collagen and cuticulin-based cuticle molting cycle | collagen and cuticulin-based cuticle extracellular matrix; collagen trimer; extracellular region | structural constituent of cuticle | Caenorhabditis elegans | Collagen Cuticle Disulfide bond Reference proteome Repeat Signal | METDGRLKAY | METDGRLKAYKFVAYAAVGFSIAAVASVLLTLPMVYSYVSHVRQQMHHEINFCKGSAKDIFAEVNYMKANAGPVPPRNRTTRQAYGGPEVNPAPNLQCEGCCLPGPPGPAGAPGKPGKPGRPGAPGTPGTPGKPPVAPCEPTTPPPCKPCPQGPPGPPGPPGAPGDPGEAGTPGRPGTDAAPGSPGPRGPPGPAGEAGAPGPAGEPGTPAISEPLTPGAPGEPGDSGPPGPPGPPGAPGNDGPPGPPGPKGAPGPDGPPGVDGQSGPPGPPGPAGTPGEKGICPKYCALDGGVFFEDGTRR | collagen and cuticulin-based cuticle development cuticle development involved in collagen and cuticulin-based cuticle molting cycle collagen and cuticulin-based cuticle extracellular matrix; collagen trimer; extracellular region structural constituent of cuticle Caenorhabditis elegansCollagen Cuticle Disulfide bond Ref... |
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