Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
|---|---|---|---|---|---|---|---|
extracellular matrix organization | collagen trimer; collagen-containing extracellular matrix; extracellular region; extracellular space; receptor complex | extracellular matrix structural constituent conferring tensile strength metal ion binding | Gallus gallus | Calcium Collagen Direct protein sequencing Extracellular matrix Hydroxylation Metal-binding Reference proteome Repeat Secreted Signal | MHLQISLLLL | MHLQISLLLLFCLNIVHGSDGYFSERYQKQSSIKGPPHFLPFNVKSQGVQMRGEQGPPGPPGPIGPRGQPGPAGKPGFGSPGPQGPPGPLGPPGFSTVGKLGMPGLPGKPGERGLNGEKGEAGPVGLPGARGPQGPPGIPGPAGLSVLGKPGPQGPPGAQGPRGPPGEKGEPGVPGINGQKGEMGFGVPGRPGNRGLPGPQGPQGLPGSAGIGKPGENGLPGQPGMKGDRGLPGARGEAGIPGPQGPPGEPGEVGIGKPGPMGPPGPAGIPGAKGLPGPAGLPGSPGLPGFGKPGLPGMKGHRGPEGPPGFPGPKGDQGP... | extracellular matrix organization collagen trimer; collagen-containing extracellular matrix; extracellular region; extracellular space; receptor complex extracellular matrix structural constituent conferring tensile strength metal ion binding Gallus gallus Calcium Collagen Direct protein sequencing Extracellular matrix... |
apoptotic signaling pathway growth plate cartilage chondrocyte differentiation mitochondrial calcium ion homeostasis monoatomic ion transmembrane transport negative regulation of sequestering of calcium ion neural crest cell migration plasma membrane repair regulation of muscle contraction | collagen-containing extracellular matrix; cytoplasm; extracellular exosome; focal adhesion; late endosome membrane; lysosomal membrane; melanosome; membrane; mitochondrion; perinuclear region of cytoplasm; sarcolemma | actin filament binding calcium channel activity calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding cholesterol binding chondroitin sulfate binding GTP binding identical protein binding ligand-gated monoatomic ion channel activity lipid binding phosphatidylserine binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Annexin Calcium Calcium/phospholipid-binding Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Repeat | MAKPAQGAKY | MAKPAQGAKYRGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTSGEYKKTLLKL... | apoptotic signaling pathway growth plate cartilage chondrocyte differentiation mitochondrial calcium ion homeostasis monoatomic ion transmembrane transport negative regulation of sequestering of calcium ion neural crest cell migration plasma membrane repair regulation of muscle contraction collagen-containing extracell... |
actin filament organization apical junction assembly mitotic cytokinesis positive regulation of canonical NF-kappaB signal transduction positive regulation of cell migration positive regulation of lipase activity positive regulation of protein-containing complex assembly positive regulation of stress fiber assembly sig... | cleavage furrow; cytosol; endoplasmic reticulum membrane; extracellular exosome; neuron projection; nucleus; plasma membrane; stereocilium | GTP binding GTPase activity protein kinase binding | Homo sapiens | 3D-structure ADP-ribosylation Cell membrane Glycoprotein GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MAAIRKKLVI | MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQVRKNKRRRGCPIL | actin filament organization apical junction assembly mitotic cytokinesis positive regulation of canonical NF-kappaB signal transduction positive regulation of cell migration positive regulation of lipase activity positive regulation of protein-containing complex assembly positive regulation of stress fiber assembly sig... |
branched-chain amino acid biosynthetic process isoleucine biosynthetic process valine biosynthetic process | acetolactate synthase complex | acetolactate synthase activity flavin adenine dinucleotide binding magnesium ion binding thiamine pyrophosphate binding | Escherichia coli | 3D-structure Amino-acid biosynthesis Branched-chain amino acid biosynthesis FAD Flavoprotein Magnesium Metal-binding Reference proteome Thiamine pyrophosphate Transferase | MASSGTTSTR | MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYDALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDSIPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQSGRPGPVWIDIPKDVQTAVFEIETQPAMAEKAAAPAFSEESIRDAAAMINAAKRPVLYLGGGVINAPARVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEADLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPH... | branched-chain amino acid biosynthetic process isoleucine biosynthetic process valine biosynthetic process acetolactate synthase complex acetolactate synthase activity flavin adenine dinucleotide binding magnesium ion binding thiamine pyrophosphate binding Escherichia coli 3D-structure Amino-acid biosynthesis Branched-... |
carbohydrate metabolic process | extracellular region; extracellular space | alpha-amylase activity calcium ion binding | Drosophila melanogaster | 3D-structure Calcium Carbohydrate metabolism Chloride Disulfide bond Glycosidase Hydrolase Metal-binding Pyrrolidone carboxylic acid Reference proteome Signal | MFLAKSIVCL | MFLAKSIVCLALLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAVKDSRPWWERYQPISYKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHMAADGGTYGTGGSTASPSSKSYPGVPYSSLDFNPTCAISNYNDANEVRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPADLAVIYGRLKNLNTDHGFASGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKVFRGKDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLT... | carbohydrate metabolic process extracellular region; extracellular space alpha-amylase activity calcium ion binding Drosophila melanogaster 3D-structure Calcium Carbohydrate metabolism Chloride Disulfide bond Glycosidase Hydrolase Metal-binding Pyrrolidone carboxylic acid Reference proteome Signal MFLAKSIVCL MFLAKSIVCL... |
cell adhesion perturbation by symbiont of host inflammatory response proteolysis symbiont-mediated activation of host signal transduction pathway | plasma membrane; side of membrane | metal ion binding metalloendopeptidase activity metallopeptidase activity | Leishmania major | 3D-structure Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Membrane Metal-binding Metalloprotease Protease Signal Zinc Zymogen | MSVDSSSTHR | MSVDSSSTHRRRCVAARLVRLAAAGAAVTVAVGTAAAWAHAGALQHRCVHDAMQARVRQSVADHHKAPGAVSAVGLPYVTLDAAHTAAAADPRPGSARSVVRDVNWGALRIAVSTEDLTDPAYHCARVGQHVKDHAGAIVTCTAEDILTNEKRDILVKHLIPQAVQLHTERLKVQQVQGKWKVTDMVGDICGDFKVPQAHITEGFSNTDFVMYVASVPSEEGVLAWATTCQTFSDGHPAVGVINIPAANIASRYDQLVTRVVTHEMAHALGFSGPFFEDARIVANVPNVRGKNFDVPVINSSTAVAKAREQYGCDTLEYL... | cell adhesion perturbation by symbiont of host inflammatory response proteolysis symbiont-mediated activation of host signal transduction pathway plasma membrane; side of membrane metal ion binding metalloendopeptidase activity metallopeptidase activity Leishmania major3D-structure Cell adhesion Cell membrane Direct pr... |
cell wall organization division septum assembly FtsZ-dependent cytokinesis peptidoglycan biosynthetic process proteolysis regulation of cell shape response to antibiotic | plasma membrane | penicillin binding peptidoglycan glycosyltransferase activity serine-type D-Ala-D-Ala carboxypeptidase activity | Neisseria gonorrhoeae | 3D-structure Antibiotic resistance Carboxypeptidase Cell cycle Cell division Cell inner membrane Cell membrane Cell shape Cell wall biogenesis/degradation Hydrolase Membrane Peptidoglycan synthesis Protease Septation Transmembrane Transmembrane helix | MLIKSEYKPR | MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAMAVLFACLIARGLYLQTVTYNFLKEQGDNRIVRTQALPATRGTVSDRNGAVLALSAPTESLFAVPKDMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFVFEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLYGEDGAEVVLRDRQGNIVDSLDSPRNKAPQNGKDIILSLDQRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKA... | cell wall organization division septum assembly FtsZ-dependent cytokinesis peptidoglycan biosynthetic process proteolysis regulation of cell shape response to antibiotic plasma membrane penicillin binding peptidoglycan glycosyltransferase activity serine-type D-Ala-D-Ala carboxypeptidase activity Neisseria gonorrhoeae3... |
aorta development brain segmentation cellular response to organic substance facial nerve structural organization fat cell differentiation gene expression learning or memory motor neuron axon guidance myelination positive regulation of DNA-templated transcription positive regulation of myelination positive regulation of... | cytoplasm; intracellular membrane-bounded organelle; nucleoplasm; nucleus | chromatin binding DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific HMG box domain binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA bi... | Mus musculus | Acetylation Activator Alternative splicing DNA-binding Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Transferase Ubl conjugation Ubl conjugation pathway Zinc Zinc-finger | MMTAKAVDKI | MMTAKAVDKIPVTLSGFMHQLPDSLYPVEDLAASSVTIFPNGELGGPFDQMNGVAGDGMINIDMTGEKRPLDLPYPSSFAPISAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTPPASTTASSSVTSASPNPLATGPLGVCTMSQTQPELDHLYSPPPPPPPYSGCTGDLYQDPSAFLSPPSTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFPSPCQRDPHGAAGPDRKPFPCPLDSLRVPPPLTPLSTIRNFTLGGPGAGVTGPGASGGGEGPRLPGSGSAAVTATPYNPHHLPLRPILRP... | aorta development brain segmentation cellular response to organic substance facial nerve structural organization fat cell differentiation gene expression learning or memory motor neuron axon guidance myelination positive regulation of DNA-templated transcription positive regulation of myelination positive regulation of... |
positive regulation of mating type switching positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | cytoplasm; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific mediator complex binding metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding | Saccharomyces cerevisiae | 3D-structure Activator Cytoplasm DNA-binding Metal-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Zinc Zinc-finger | MDTSNSWFDA | MDTSNSWFDASKVQSLNFDLQTNSYYSNARGSDPSSYAIEGEYKTLATDDLGNILNLNYGETNEVIMNEINDLNLPLGPLSDEKSVKVSTFSELIGNDWQSMNFDLENNSREVTLNATSLLNENRLNQDSGMTVYQKTMSDKPHDEKKISMADNLLSTINKSEINKGFDRNLGELLLQQQQELREQLRAQQEANKKLELELKQTQYKQQQLQATLENSDGPQFLSPKRKISPASENVEDVYANSLSPMISPPMSNTSFTGSPSRRNNRQKYCLQRKNSSGTVGPLCFQELNEGFNDSLISPKKIRSNPNENLSSKTKFIT... | positive regulation of mating type switching positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoplasm; nucleus DNA-binding transcription factor activity, RNA polymerase II-specific mediator complex binding metal ion binding RNA polymerase II cis-regulatory reg... |
metamorphosis negative regulation of compound eye photoreceptor development negative regulation of neuron projection development regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to ecdysone response to starvation | cytosol; nucleus | DNA-binding transcription factor activity metal ion binding RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Alternative splicing Developmental protein DNA-binding Metal-binding Reference proteome Repeat Zinc Zinc-finger | MTESKNDTKS | MTESKNDTKSWAPKQIWIKDVLKKSGTELLDISKSPAKAVAVKKSPAKDSATTKMVYYSANQLLIKTEQSSQAQFCLQVPPPLTATTTSVGLGVPPSGGQQEHFELLQTPQQRQMQLQLQDQHQQEQQQFVSYQLAIQQHQKQQQQQQHESITNAAPTAAPSAQRIKTEPVGGFPASAAVVSQVRKPSASKPQFKCDQCGMTFGSKSAHTSHTKSHSKNQDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRI... | metamorphosis negative regulation of compound eye photoreceptor development negative regulation of neuron projection development regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to ecdysone response to starvation cytosol; nucleus DNA-binding transcription factor activi... |
acetaldehyde catabolic process acetate biosynthetic process carbon catabolite activation of transcription cellular response to osmotic stress ethanol catabolic process ethanol metabolic process threonine catabolic process | extracellular region | aldehyde dehydrogenase (NAD+) activity aldehyde dehydrogenase activity glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity | Emericella nidulans | NAD Oxidoreductase Reference proteome | MSDLFTTIET | MSDLFTTIETPVIKYEQPLGLFINNEFVKGVEGKTFQVINPSNEKVITSVHEATEKDVDVAVAAARAAFEGPWRQVTPSERGILINKLADLMERDIDTLAAIESLDNGKAFTMAKVDLANSIGCLRYYAGWADKIHGQTIDTNPETLTYTRHEPVGVCGQIIPWNFPLLMWSWKIGPAVAAGNTVVLKTAEQTPLSALYAAKLIKEAGFPAGVINVISGFGRTAGAAISSHMDIDKVAFTGSTLVGRTILQAAAKSNLKKVTLELGGKSPNIVFDDADIDNAISWANFGIFFNHGQCCCAGSRILVQEGIYDKFVARFKE... | acetaldehyde catabolic process acetate biosynthetic process carbon catabolite activation of transcription cellular response to osmotic stress ethanol catabolic process ethanol metabolic process threonine catabolic process extracellular region aldehyde dehydrogenase (NAD+) activity aldehyde dehydrogenase activity glyce... |
alkaloid metabolic process nicotine catabolic process | cytoplasm | (R)-6-hydroxynicotine oxidase activity FAD binding | Paenarthrobacter nicotinovorans | 3D-structure Alkaloid metabolism Cytoplasm FAD Flavoprotein Nucleotide-binding Oxidoreductase Plasmid | MSSKLATPLS | MSSKLATPLSIQGEVIYPDDSGFDAIANIWDGRHLQRPSLIARCLSAGDVAKSVRYACDNGLEISVRSGGHNPNGYATNDGGIVLDLRLMNSIHIDTAGSRARIGGGVISGDLVKEAAKFGLAAVTGMHPKVGFCGLALNGGVGFLTPKYGLASDNILGATLVTATGDVIYCSDDERPELFWAVRGAGPNFGVVTEVEVQLYELPRKMLAGFITWAPSVSELAGLLTSLLDALNEMADHIYPSVFVGVDENRAPSVTVCVGHLGGLDIAERDIARLRGLGRTVSDSIAVRSYDEVVALNAEVGSFEDGMSNLWIDREIAM... | alkaloid metabolic process nicotine catabolic process cytoplasm (R)-6-hydroxynicotine oxidase activity FAD binding Paenarthrobacter nicotinovorans 3D-structure Alkaloid metabolism Cytoplasm FAD Flavoprotein Nucleotide-binding Oxidoreductase Plasmid MSSKLATPLS MSSKLATPLSIQGEVIYPDDSGFDAIANIWDGRHLQRPSLIARCLSAGDVAKSVRYACDN... |
NAD biosynthetic process sporulation resulting in formation of a cellular spore | cytoplasm | ATP binding glutaminase activity metal ion binding NAD+ synthase (glutamine-hydrolyzing) activity NAD+ synthase activity | Bacillus subtilis | 3D-structure ATP-binding Direct protein sequencing Ligase Magnesium Metal-binding NAD Nucleotide-binding Phosphoprotein Reference proteome Sporulation Stress response | MSMQEKIMRE | MSMQEKIMRELHVKPSIDPKQEIEDRVNFLKQYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVESIREEGGDAQFIAVRLPHGTQQDEDDAQLALKFIKPDKSWKFDIKSTVSAFSDQYQQETGDQLTDFNKGNVKARTRMIAQYAIGGQEGLLVLGTDHAAEAVTGFFTKYGDGGADLLPLTGLTKRQGRTLLKELGAPERLYLKEPTADLLDEKPQQSDETELGISYDEIDDYLEGKEVSAKVSEALEKRYSMTEHKRQVPASMFDDWWK | NAD biosynthetic process sporulation resulting in formation of a cellular spore cytoplasm ATP binding glutaminase activity metal ion binding NAD+ synthase (glutamine-hydrolyzing) activity NAD+ synthase activity Bacillus subtilis 3D-structure ATP-binding Direct protein sequencing Ligase Magnesium Metal-binding NAD Nucle... |
ADP biosynthetic process AMP metabolic process ATP metabolic process phosphorylation | cytoplasm; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; sperm mitochondrial sheath | adenylate kinase activity ATP binding | Bos taurus | 3D-structure Acetylation Alternative splicing ATP-binding Direct protein sequencing Disulfide bond Kinase Mitochondrion Nucleotide-binding Phosphoprotein Reference proteome Transferase | MAPNVPAAEP | MAPNVPAAEPVPESPKGVRAVLLGPPGAGKGTQAPKLAKNFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVLELIEKNLETPPCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPQSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNKKALKIRLEAYHTQTTPLVEYYSKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI | ADP biosynthetic process AMP metabolic process ATP metabolic process phosphorylation cytoplasm; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrion; sperm mitochondrial sheath adenylate kinase activity ATP binding Bos taurus 3D-structure Acetylation Alternative splicing ATP-binding Direct pro... |
G protein-coupled receptor internalization response to light stimulus signal transduction | cytosol; membrane; photoreceptor inner segment; photoreceptor outer segment | G protein-coupled receptor binding identical protein binding opsin binding phosphoprotein binding | Bos taurus | 3D-structure Acetylation Alternative splicing Cell projection Direct protein sequencing Membrane Phosphoprotein Reference proteome | MKANKPAPNH | MKANKPAPNHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANTYPFLLTFPDYLPCSVMLQPAPQDVGKSCGVDFEIKAFATHSTDVEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNVVLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDKTV... | G protein-coupled receptor internalization response to light stimulus signal transduction cytosol; membrane; photoreceptor inner segment; photoreceptor outer segment G protein-coupled receptor binding identical protein binding opsin binding phosphoprotein binding Bos taurus 3D-structure Acetylation Alternative splicing... |
fatty acid biosynthetic process fatty acid oxidation lipid oxidation oxylipin biosynthetic process | cytoplasm | iron ion binding linoleate 13S-lipoxygenase activity linolenate 9R-lipoxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | Glycine max | 3D-structure Cytoplasm Dioxygenase Direct protein sequencing Fatty acid biosynthesis Fatty acid metabolism Iron Lipid biosynthesis Lipid metabolism Metal-binding Oxidoreductase Oxylipin biosynthesis Reference proteome | MFSAGHKIKG | MFSAGHKIKGTVVLMPKNELEVNPDGSAVDNLNAFLGRSVSLQLISATKADAHGKGKVGKDTFLEGINTSLPTLGAGESAFNIHFEWDGSMGIPGAFYIKNYMQVEFFLKSLTLEAISNQGTIRFVCNSWVYNTKLYKSVRIFFANHTYVPSETPAPLVSYREEELKSLRGNGTGERKEYDRIYDYDVYNDLGNPDKSEKLARPVLGGSSTFPYPRRGRTGRGPTVTDPNTEKQGEVFYVPRDENLGHLKSKDALEIGTKSLSQIVQPAFESAFDLKSTPIEFHSFQDVHDLYEGGIKLPRDVISTIIPLPVIKELYRTD... | fatty acid biosynthetic process fatty acid oxidation lipid oxidation oxylipin biosynthetic process cytoplasm iron ion binding linoleate 13S-lipoxygenase activity linolenate 9R-lipoxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxy... |
courtship behavior mating organic substance catabolic process ovulation pheromone biosynthetic process regulation of egg-laying behavior regulation of female receptivity, post-mating sexual reproduction sperm storage | extracellular region; extracellular space | carboxylesterase activity serine hydrolase activity short-chain carboxylesterase activity | Drosophila melanogaster | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Reference proteome Secreted Serine esterase Signal | MNYVGLGLII | MNYVGLGLIIVLSCLWLGSNASDTDDPLLVQLPQGKLRGRDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQWDQFTPGANKLVGEEDCLTVSVYKPKNSKRNSFPVVAHIHGGAFMFGAAWQNGHENVMREGKFILVKISYRLGPLGFVSTGDRDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLLVGHSAGGASVHLQMLREDFGQLARAAFSFSGNALDPWVIQKGARGRAFELGRNVGCESAEDSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPRD... | courtship behavior mating organic substance catabolic process ovulation pheromone biosynthetic process regulation of egg-laying behavior regulation of female receptivity, post-mating sexual reproduction sperm storage extracellular region; extracellular space carboxylesterase activity serine hydrolase activity short-cha... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled recep... | asymmetric synapse; axon terminus; cholinergic synapse; clathrin-coated endocytic vesicle membrane; dendrite; glutamatergic synapse; membrane; neuronal cell body; plasma membrane; postsynaptic membrane; presynaptic membrane; symmetric synapse; synapse | arrestin family protein binding G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MNNSTNSSNN | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENS... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled recep... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway cell surface receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation... | dendrite; plasma membrane; postsynaptic membrane; synapse | G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MANFTPVNGS | MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATELSTTEATT... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway cell surface receptor signaling pathway chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation... |
complement activation, classical pathway innate immune response negative regulation of complement activation positive regulation of CD4-positive, alpha-beta T cell activation positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of cytosolic calcium ion concentration positive regulati... | cell surface; endoplasmic reticulum-Golgi intermediate compartment membrane; extracellular exosome; extracellular region; ficolin-1-rich granule membrane; Golgi membrane; membrane raft; plasma membrane; secretory granule membrane; side of membrane; transport vesicle | lipid binding virus receptor activity | Homo sapiens | 3D-structure Alternative splicing Blood group antigen Cell membrane Complement pathway Direct protein sequencing Disease variant Disulfide bond Glycoprotein GPI-anchor Host cell receptor for virus entry Host-virus interaction Immunity Innate immunity Lipoprotein Membrane Receptor Reference proteome Repeat Secreted Sign... | MTVARPSVPA | MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKT... | complement activation, classical pathway innate immune response negative regulation of complement activation positive regulation of CD4-positive, alpha-beta T cell activation positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of cytosolic calcium ion concentration positive regulati... |
proteolysis | extracellular region | cysteine-type peptidase activity | Dermatophagoides pteronyssinus | 3D-structure Allergen Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Signal Thiol protease Zymogen | MKIVLAIASL | MKIVLAIASLLALSAVYARPSSIKTFEEYKKAFNKSYATFEDEEAARKNFLESVKYVQSNGGAINHLSDLSLDEFKNRFLMSAEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCASQHGCHGDTIPRGIEYIQHNGVVQESYYRYVAREQSCRRPNAQRFGISNYCQIYPPNVNKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAANIDLMMIEEYPYVVIL | proteolysis extracellular region cysteine-type peptidase activity Dermatophagoides pteronyssinus 3D-structure Allergen Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Secreted Signal Thiol protease Zymogen MKIVLAIASL MKIVLAIASLLALSAVYARPSSIKTFEEYKKAFNKSYATFEDEEAARKNFLESVKYVQS... |
de novo' IMP biosynthetic process DNA damage response | cytoplasm; cytosol | phosphoribosylglycinamide formyltransferase activity | Escherichia coli | 3D-structure Direct protein sequencing Purine biosynthesis Reference proteome Transferase | MNIVVLISGN | MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE | de novo' IMP biosynthetic process DNA damage response cytoplasm; cytosol phosphoribosylglycinamide formyltransferase activity Escherichia coli 3D-structure Direct protein sequencing Purine biosynthesis Reference proteome Transferase MNIVVLISGN MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEID... |
aggressive behavior chaeta development circadian rhythm compound eye development intracellular mRNA localization involved in pattern specification process lateral inhibition locomotor rhythm mitotic cell cycle negative regulation of proteasomal ubiquitin-dependent protein catabolic process oocyte dorsal/ventral axis sp... | cytoplasm; cytosol; nucleolus; nucleus; protein kinase CK2 complex | ATP binding protein serine kinase activity protein serine/threonine kinase activity | Drosophila melanogaster | ATP-binding Direct protein sequencing Kinase Nucleotide-binding Nucleus Reference proteome Serine/threonine-protein kinase Transferase Wnt signaling pathway | MTLPSAARVY | MTLPSAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHP... | aggressive behavior chaeta development circadian rhythm compound eye development intracellular mRNA localization involved in pattern specification process lateral inhibition locomotor rhythm mitotic cell cycle negative regulation of proteasomal ubiquitin-dependent protein catabolic process oocyte dorsal/ventral axis sp... |
circadian rhythm eclosion rhythm intracellular mRNA localization involved in pattern specification process locomotor rhythm mushroom body development oocyte dorsal/ventral axis specification protein phosphorylation regulation of synapse organization rhythmic behavior Wnt signaling pathway | cytoplasm; cytosol; neuromuscular junction; nucleus; presynaptic cytosol; protein kinase CK2 complex | protein kinase regulator activity | Drosophila melanogaster | Alternative splicing Phosphoprotein Reference proteome Wnt signaling pathway | MSSSEEVSWV | MSSSEEVSWVTWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPNYRQALDMILDLEPEDELEDNPLQSDMTEQAAEMLYGLIHARYILTNRGIAQMIEKYQTGDFGHCPRVYCESQPMLPLGLSDIPGEAMVKTYCPKCIDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPTNQFVPRLYGFKIHSLAYQIQLQAAANFKMPLRAQRGQPPKDEEPENNADTVPKRL | circadian rhythm eclosion rhythm intracellular mRNA localization involved in pattern specification process locomotor rhythm mushroom body development oocyte dorsal/ventral axis specification protein phosphorylation regulation of synapse organization rhythmic behavior Wnt signaling pathway cytoplasm; cytosol; neuromuscu... |
glucocorticoid metabolic process | extracellular exosome; extracellular region; extracellular space | serine-type endopeptidase inhibitor activity steroid binding | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Glycoprotein Lipid-binding Reference proteome Secreted Signal Steroid-binding Transport | MPLLLYTCLL | MPLLLYTCLLWLPTSGLWTVQAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMG... | glucocorticoid metabolic process extracellular exosome; extracellular region; extracellular space serine-type endopeptidase inhibitor activity steroid binding Homo sapiens 3D-structure Direct protein sequencing Disease variant Glycoprotein Lipid-binding Reference proteome Secreted Signal Steroid-binding Transport MPLLL... |
cell adhesion cell adhesion involved in single-species biofilm formation cell-substrate adhesion mechanosensory behavior | host cell membrane; pilus; pilus tip | mannose binding | Escherichia coli | 3D-structure Direct protein sequencing Fimbrium Reference proteome Signal | MKRVITLFAV | MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTANYARTGGQVTAGNVQSIIGVTFVYQ | cell adhesion cell adhesion involved in single-species biofilm formation cell-substrate adhesion mechanosensory behavior host cell membrane; pilus; pilus tip mannose binding Escherichia coli 3D-structure Direct protein sequencing Fimbrium Reference proteome Signal MKRVITLFAV MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVN... |
folic acid biosynthetic process folic acid-containing compound biosynthetic process one-carbon metabolic process tetrahydrofolate biosynthetic process | cytoplasm | ATP binding dihydrofolate synthase activity guanosine tetraphosphate binding metal ion binding tetrahydrofolylpolyglutamate synthase activity | Escherichia coli | 3D-structure ATP-binding Folate biosynthesis Ligase Magnesium Metal-binding Nucleotide-binding One-carbon metabolism Reference proteome | MIIKRTPQAA | MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSLVAARLGVLKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPESAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVDADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKAL... | folic acid biosynthetic process folic acid-containing compound biosynthetic process one-carbon metabolic process tetrahydrofolate biosynthetic process cytoplasm ATP binding dihydrofolate synthase activity guanosine tetraphosphate binding metal ion binding tetrahydrofolylpolyglutamate synthase activity Escherichia coli ... |
amino acid transport calcium ion transport carbohydrate metabolic process isoleucine transport L-alanine import across plasma membrane L-histidine transport L-leucine import across plasma membrane leucine import across plasma membrane leucine transport methionine transport phenylalanine transport proline transport resp... | amino acid transport complex; anchoring junction; apical plasma membrane; apical pole of neuron; basal plasma membrane; basolateral plasma membrane; cell surface; extracellular exosome; lysosomal membrane; melanosome; membrane; nucleoplasm; plasma membrane; synapse | aromatic amino acid transmembrane transporter activity cadherin binding calcium:sodium antiporter activity double-stranded RNA binding exogenous protein binding L-alanine transmembrane transporter activity L-leucine transmembrane transporter activity neutral L-amino acid secondary active transmembrane transporter activ... | Homo sapiens | 3D-structure Acetylation Alternative splicing Amino-acid transport Cell junction Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Host cell receptor for virus entry Isopeptide bond Lysosome Membrane Phosphoprotein Receptor Reference proteome Signal-anchor Transmembrane Transmembrane helix Transport U... | MELQPPEASI | MELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAGLQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFS... | amino acid transport calcium ion transport carbohydrate metabolic process isoleucine transport L-alanine import across plasma membrane L-histidine transport L-leucine import across plasma membrane leucine import across plasma membrane leucine transport methionine transport phenylalanine transport proline transport resp... |
electron transport chain glyoxylate cycle response to oxidative stress tricarboxylic acid cycle | cytoplasm; cytosol | guanosine tetraphosphate binding isocitrate dehydrogenase (NADP+) activity magnesium ion binding NAD binding | Escherichia coli | 3D-structure Acetylation Direct protein sequencing Glyoxylate bypass Magnesium Manganese Metal-binding NADP Oxidoreductase Phosphoprotein Reference proteome Tricarboxylic acid cycle | MESKVVVPAQ | MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGI... | electron transport chain glyoxylate cycle response to oxidative stress tricarboxylic acid cycle cytoplasm; cytosol guanosine tetraphosphate binding isocitrate dehydrogenase (NADP+) activity magnesium ion binding NAD binding Escherichia coli 3D-structure Acetylation Direct protein sequencing Glyoxylate bypass Magnesium ... |
fermentation NADH oxidation nitrate assimilation | nitrite reductase complex | 2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster binding flavin adenine dinucleotide binding heme binding metal ion binding NADP binding nitrite reductase NADH activity | Escherichia coli | 4Fe-4S FAD Flavoprotein Heme Iron Iron-sulfur Metal-binding NAD Nitrate assimilation Oxidoreductase Reference proteome | MSKVRLAIIG | MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAYDRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFYDKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEAAGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGVEARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDIYAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLS... | fermentation NADH oxidation nitrate assimilation nitrite reductase complex 2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster binding flavin adenine dinucleotide binding heme binding metal ion binding NADP binding nitrite reductase NADH activity Escherichia coli 4Fe-4S FAD Flavoprotein Heme Iron Iron-sulfur Met... |
L-arabinose catabolic process to xylulose 5-phosphate L-lyxose metabolic process pentose catabolic process | cytosol; protein-containing complex | aldehyde-lyase activity identical protein binding L-ribulose-phosphate 4-epimerase activity zinc ion binding | Escherichia coli | 3D-structure Arabinose catabolism Carbohydrate metabolism Cobalt Direct protein sequencing Isomerase Manganese Metal-binding Reference proteome Zinc | MLEDLKRQVL | MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ | L-arabinose catabolic process to xylulose 5-phosphate L-lyxose metabolic process pentose catabolic process cytosol; protein-containing complex aldehyde-lyase activity identical protein binding L-ribulose-phosphate 4-epimerase activity zinc ion binding Escherichia coli 3D-structure Arabinose catabolism Carbohydrate meta... |
membrane raft assembly mRNA transcription by RNA polymerase II positive regulation of exocytosis positive regulation of focal adhesion assembly positive regulation of plasma membrane repair positive regulation of plasminogen activation positive regulation of stress fiber assembly positive regulation of substrate adhesi... | AnxA2-p11 complex; cell surface; collagen-containing extracellular matrix; cytoplasm; extracellular space; membrane raft; nuclear matrix; plasma membrane; plasma membrane protein complex; RNA polymerase II transcription regulator complex | calcium ion binding calcium-dependent protein binding protein homodimerization activity transmembrane transporter binding | Mus musculus | Acetylation Reference proteome Repeat | MPSQMEHAME | MPSQMEHAMETMMLTFHRFAGDKDHLTKEDLRVLMEREFPGFLENQKDPLAVDKIMKDLDQCRDGKVGFQSFLSLVAGLTIACNDYFVVNMKQKGKK | membrane raft assembly mRNA transcription by RNA polymerase II positive regulation of exocytosis positive regulation of focal adhesion assembly positive regulation of plasma membrane repair positive regulation of plasminogen activation positive regulation of stress fiber assembly positive regulation of substrate adhesi... |
insulin catabolic process proteolysis regulation of insulin secretion regulation of platelet aggregation response to insulin | cytosol; extracellular region; extracellular space; keratohyalin granule | endopeptidase activity serine hydrolase activity serine-type endopeptidase activity | Homo sapiens | Diabetes mellitus Direct protein sequencing Disease variant Disulfide bond Hydrolase Obesity Protease Reference proteome Secreted Serine protease Signal Zymogen | MIRTLLLSTL | MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWINSVIANN | insulin catabolic process proteolysis regulation of insulin secretion regulation of platelet aggregation response to insulin cytosol; extracellular region; extracellular space; keratohyalin granule endopeptidase activity serine hydrolase activity serine-type endopeptidase activity Homo sapiens Diabetes mellitus Direct ... |
proteolysis | extracellular region; extracellular space | serine-type endopeptidase activity | Homo sapiens | Disulfide bond Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MIRTLLLSTL | MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGQLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVIANN | proteolysis extracellular region; extracellular space serine-type endopeptidase activity Homo sapiens Disulfide bond Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen MIRTLLLSTL MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSD... |
chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly regulation of postsynaptic membrane potential synaptic transmission, GABAergic | chloride channel complex; cytoplasmic vesicle membrane; dendrite membrane; GABA-A receptor complex; neuron projection; postsynapse; postsynaptic membrane; synapse | GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity | Bos taurus | Cell membrane Chloride Chloride channel Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MKKSPGLSDY | MKKSPGLSDYLWAWTLFLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVC... | chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly regulation of postsynaptic membrane potential synaptic transmission, GABAergic chloride channel complex; cytoplasmic vesicle membrane; dendrite membrane; GABA-A receptor complex; neuron projection; postsynapse; postsy... |
cellular response to histamine chloride transmembrane transport gamma-aminobutyric acid signaling pathway monoatomic ion transport | chloride channel complex; GABA-A receptor complex; GABA-ergic synapse; neuron projection; plasma membrane; postsynaptic membrane; Schaffer collateral - CA1 synapse; synapse | G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential GABA-A receptor activity GABA-gated chloride ion channel activity ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potenti... | Bos taurus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MWTVQNRESL | MWTVQNRESLGLLSFPVMIAMVCCAHSANEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLA... | cellular response to histamine chloride transmembrane transport gamma-aminobutyric acid signaling pathway monoatomic ion transport chloride channel complex; GABA-A receptor complex; GABA-ergic synapse; neuron projection; plasma membrane; postsynaptic membrane; Schaffer collateral - CA1 synapse; synapse G protein-couple... |
intracellular steroid hormone receptor signaling pathway positive regulation of non-canonical NF-kappaB signal transduction regulation of transcription by RNA polymerase II signal transduction | chromatin; cytosol; endoplasmic reticulum membrane; nucleoplasm; receptor complex | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific estrogen response element binding nuclear receptor activity nuclear steroid receptor activity sequence-specific double-stranded DNA binding steroid binding TBP-class protein binding zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Disease variant DNA-binding Endoplasmic reticulum Lipid-binding Membrane Metal-binding Nucleus Phosphoprotein Receptor Reference proteome Steroid-binding Transcription Transcription regulation Zinc Zinc-finger | METKGYHSLP | METKGYHSLPEGLDMERRWGQVSQAVERSSLGPTERTDENNYMEIVNVSCVSGAIPNNSTQGSSKEKQELLPCLQQDNNRPGILTSDIKTELESKELSATVAESMGLYMDSVRDADYSYEQQNQQGSMSPAKIYQNVEQLVKFYKGNGHRPSTLSCVNTPLRSFMSDSGSSVNGGVMRAVVKSPIMCHEKSPSVCSPLNMTSSVCSPAGINSVSSTTASFGSFPVHSPITQGTPLTCSPNVENRGSRSHSPAHASNVGSPLSSPLSSMKSSISSPPSHCSVKSPVSSPNNVTLRSSVSSPANINNSRCSVSSPSNTNNRS... | intracellular steroid hormone receptor signaling pathway positive regulation of non-canonical NF-kappaB signal transduction regulation of transcription by RNA polymerase II signal transduction chromatin; cytosol; endoplasmic reticulum membrane; nucleoplasm; receptor complex DNA-binding transcription factor activity DNA... |
carbohydrate metabolic process chondroitin sulfate catabolic process glucuronoside catabolic process glycosaminoglycan catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process | azurophil granule lumen; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; intracellular membrane-bounded organelle; lysosomal lumen; membrane | beta-glucuronidase activity carbohydrate binding protein domain specific binding signaling receptor binding | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Disease variant Glycoprotein Glycosidase Hydrolase Lysosome Mucopolysaccharidosis Reference proteome Signal | MARGSAVAWA | MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTTLPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFY... | carbohydrate metabolic process chondroitin sulfate catabolic process glucuronoside catabolic process glycosaminoglycan catabolic process heparan sulfate proteoglycan catabolic process hyaluronan catabolic process azurophil granule lumen; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich g... |
canonical glycolysis fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process glucose homeostasis glycogen catabolic process glycolysis from storage polysaccharide through glucose-1-phosphate glycolytic process glycolytic process through fructose-6-phosphate muscle cell cellular homeostasis po... | 6-phosphofructokinase complex; apical plasma membrane; cytosol; membrane; nucleus; sperm principal piece | 6-phosphofructokinase activity AMP binding ATP binding fructose binding fructose-6-phosphate binding identical protein binding kinase binding metal ion binding monosaccharide binding | Homo sapiens | 3D-structure Acetylation Allosteric enzyme Alternative splicing ATP-binding Cytoplasm Disease variant Glycogen storage disease Glycolysis Glycoprotein Hydroxylation Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Transferase | MTHEEHHAAK | MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEA... | canonical glycolysis fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process glucose homeostasis glycogen catabolic process glycolysis from storage polysaccharide through glucose-1-phosphate glycolytic process glycolytic process through fructose-6-phosphate muscle cell cellular homeostasis po... |
cotranslational protein targeting to membrane intracellular protein transport protein targeting to ER SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition | endoplasmic reticulum membrane; extracellular exosome; membrane; signal recognition particle receptor complex | ATP hydrolysis activity GTP binding GTPase activity RNA binding signal recognition particle binding | Homo sapiens | 3D-structure Alternative splicing Endoplasmic reticulum GTP-binding Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome | MLDFFTIFSK | MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDNQFELVFVVGFQKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFEDSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELIRRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINLIRGTGSGGQLQDLDCSSSDDEGAAQNSTKPSATKGTLGGM... | cotranslational protein targeting to membrane intracellular protein transport protein targeting to ER SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition endoplasmic reticulum membrane; extracellular exosome; membrane; signal recognition particle receptor complex ATP hydrolysis acti... |
asparagine biosynthetic process cellular response to glucose starvation glutamine metabolic process L-asparagine biosynthetic process negative regulation of apoptotic process positive regulation of mitotic cell cycle | cytosol | asparagine synthase (glutamine-hydrolyzing) activity ATP binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Amino-acid biosynthesis Asparagine biosynthesis ATP-binding Disease variant Glutamine amidotransferase Intellectual disability Ligase Nucleotide-binding Phosphoprotein Reference proteome | MCGIWALFGS | MCGIWALFGSDDCLSVQCLSAMKIAHRGPDAFRFENVNGYTNCCFGFHRLAVVDPLFGMQPIRVKKYPYLWLCYNGEIYNHKKMQQHFEFEYQTKVDGEIILHLYDKGGIEQTICMLDGVFAFVLLDTANKKVFLGRDTYGVRPLFKAMTEDGFLAVCSEAKGLVTLKHSATPFLKVEPFLPGHYEVLDLKPNGKVASVEMVKYHHCRDVPLHALYDNVEKLFPGFEIETVKNNLRILFNNAVKKRLMTDRRIGCLLSGGLDSSLVAATLLKQLKEAQVQYPLQTFAIGMEDSPDLLAARKVADHIGSEHYEVLFNSEEG... | asparagine biosynthetic process cellular response to glucose starvation glutamine metabolic process L-asparagine biosynthetic process negative regulation of apoptotic process positive regulation of mitotic cell cycle cytosol asparagine synthase (glutamine-hydrolyzing) activity ATP binding Homo sapiens 3D-structure Acet... |
de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process nucleobase-containing small molecule interconversion | cytoplasm; cytosol | carboxy-lyase activity orotidine-5'-phosphate decarboxylase activity | Escherichia coli | 3D-structure Decarboxylase Lyase Pyrimidine biosynthesis Reference proteome | MTLTASSSSR | MTLTASSSSRAVTNSPVVVALDYHNRDDALAFVDKIDPRDCRLKVGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLVDLGMTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKAINASLQRSA | de novo' pyrimidine nucleobase biosynthetic process 'de novo' UMP biosynthetic process nucleobase-containing small molecule interconversion cytoplasm; cytosol carboxy-lyase activity orotidine-5'-phosphate decarboxylase activity Escherichia coli 3D-structure Decarboxylase Lyase Pyrimidine biosynthesis Reference proteome... |
acute inflammatory response to antigenic stimulus biosynthetic process of antibacterial peptides active against Gram-negative bacteria defense response to bacterium extracellular matrix disassembly intracellular calcium ion homeostasis leukocyte migration involved in inflammatory response negative regulation of chemoki... | azurophil granule lumen; cell surface; collagen-containing extracellular matrix; cytoplasm; cytosol; extracellular exosome; extracellular region; extracellular space; phagocytic vesicle; secretory granule; specific granule lumen; transcription repressor complex | cytokine binding endopeptidase activity heparin binding peptidase activity protease binding serine-type endopeptidase activity transcription corepressor activity | Homo sapiens | 3D-structure Cytoplasmic vesicle Direct protein sequencing Disease variant Disulfide bond Glycoprotein Hydrolase Protease Reference proteome Serine protease Signal Zymogen | MTLGRRLACL | MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPRDPDPASRTH | acute inflammatory response to antigenic stimulus biosynthetic process of antibacterial peptides active against Gram-negative bacteria defense response to bacterium extracellular matrix disassembly intracellular calcium ion homeostasis leukocyte migration involved in inflammatory response negative regulation of chemoki... |
cellular response to organic substance endocytosis regulation of long-term neuronal synaptic plasticity regulation of neuronal synaptic plasticity regulation of opioid receptor signaling pathway regulation of short-term neuronal synaptic plasticity regulation of synaptic vesicle exocytosis synaptic vesicle endocytosis ... | excitatory synapse; neuromuscular junction; neuron projection; perinuclear region of cytoplasm; presynaptic active zone; presynaptic membrane; Schaffer collateral - CA1 synapse; synaptic vesicle; synaptic vesicle membrane; terminal bouton | cholesterol binding identical protein binding SH2 domain binding | Homo sapiens | Alternative splicing Calcium Cytoplasmic vesicle Disease variant Glycoprotein Intellectual disability Membrane Phosphoprotein Reference proteome Repeat Synapse Synaptosome Transmembrane Transmembrane helix Ubl conjugation | MLLLADMDVV | MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANKTESDLSIEVEFEYPFRLHQVYFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMGALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEMPVCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGDYGQQGYGPQGAPTSFSNQM | cellular response to organic substance endocytosis regulation of long-term neuronal synaptic plasticity regulation of neuronal synaptic plasticity regulation of opioid receptor signaling pathway regulation of short-term neuronal synaptic plasticity regulation of synaptic vesicle exocytosis synaptic vesicle endocytosis ... |
aerobic respiration gluconeogenesis glyceraldehyde-3-phosphate biosynthetic process malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle | cytoplasm; membrane; mitochondrial inner membrane; mitochondrial matrix; mitochondrion; myelin sheath | L-malate dehydrogenase activity malate dehydrogenase (NADP+) activity malate dehydrogenase activity protein homodimerization activity protein self-association | Mus musculus | Acetylation Direct protein sequencing Glycoprotein Mitochondrion NAD Oxidoreductase Phosphoprotein Reference proteome Transit peptide Tricarboxylic acid cycle | MLSALARPAG | MLSALARPAGAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVQSKETECTYFSTPLLLGKKGLEKNLGIGKITPFEEKMIAEAI... | aerobic respiration gluconeogenesis glyceraldehyde-3-phosphate biosynthetic process malate metabolic process NADH metabolic process oxaloacetate metabolic process tricarboxylic acid cycle cytoplasm; membrane; mitochondrial inner membrane; mitochondrial matrix; mitochondrion; myelin sheath L-malate dehydrogenase activit... |
cell wall macromolecule catabolic process chitin catabolic process defense response polysaccharide catabolic process | vacuole | chitin binding chitinase activity | Nicotiana tabacum | Carbohydrate metabolism Chitin degradation Chitin-binding Disulfide bond Glycosidase Hydrolase Hydroxylation Plant defense Polysaccharide degradation Reference proteome Signal Vacuole | MRLCKFTALS | MRLCKFTALSSLLFSLLLLSASAEQCGSQAGGARCPSGLCCSKFGWCGNTNDYCGPGNCQSQCPGGPTPTPPTPPGGGDLGSIISSSMFDQMLKHRNDNACQGKGFYSYNAFINAARSFPGFGTSGDTTARKREIAAFFAQTSHETTGGWATAPDGPYAWGYCWLREQGSPGDYCTPSGQWPCAPGRKYFGRGPIQISHNYNYGPCGRAIGVDLLNNPDLVATDPVISFKSALWFWMTPQSPKPSCHDVIIGRWQPSAGDRAANRLPGFGVITNIINGGLECGRGTDSRVQDRIGFYRRYCSILGVSPGDNLDCGNQRSF... | cell wall macromolecule catabolic process chitin catabolic process defense response polysaccharide catabolic process vacuole chitin binding chitinase activity Nicotiana tabacum Carbohydrate metabolism Chitin degradation Chitin-binding Disulfide bond Glycosidase Hydrolase Hydroxylation Plant defense Polysaccharide degra... |
cellular response to lipopolysaccharide cellular response to nitric oxide cellular response to reactive oxygen species cellular response to UV-A collagen catabolic process extracellular matrix disassembly extracellular matrix organization innate immune response negative regulation of reactive oxygen species metabolic p... | cytoplasm; extracellular matrix; extracellular region; extracellular space; nucleus | endopeptidase activity metalloendopeptidase activity metallopeptidase activity peptidase activity serine-type endopeptidase activity zinc ion binding | Homo sapiens | 3D-structure Calcium Collagen degradation Cytoplasm Direct protein sequencing Disulfide bond Extracellular matrix Hydrolase Immunity Innate immunity Metal-binding Metalloprotease Nucleus Protease Reference proteome Repeat Secreted Signal Zinc Zymogen | MKSLPILLLL | MKSLPILLLLCVAVCSAYPLDGAARGEDTSMNLVQKYLENYYDLKKDVKQFVRRKDSGPVVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPLYHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAVSTLRGEILIFKDRHFWRKSLR... | cellular response to lipopolysaccharide cellular response to nitric oxide cellular response to reactive oxygen species cellular response to UV-A collagen catabolic process extracellular matrix disassembly extracellular matrix organization innate immune response negative regulation of reactive oxygen species metabolic p... |
cellular response to light stimulus detection of UV G protein-coupled receptor signaling pathway phototransduction phototransduction, UV visual perception | membrane | G protein-coupled photoreceptor activity | Drosophila melanogaster | Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Photoreceptor protein Receptor Reference proteome Retinal protein Sensory transduction Transducer Transmembrane Transmembrane helix Vision | MEPLCNASEP | MEPLCNASEPPLRPEARSSGNGDLQFLGWNVPPDQIQYIPEHWLTQLEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLKAPIFIYNSFHRGFALGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNRNMTFTKAVIMNIIIWLYCTPWVVLPLTQFWDRFVPEGYLTSCSFDYLSDNFDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLRSNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAFGDKSLLTPGATMIPA... | cellular response to light stimulus detection of UV G protein-coupled receptor signaling pathway phototransduction phototransduction, UV visual perception membrane G protein-coupled photoreceptor activity Drosophila melanogaster Chromophore Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein ... |
epithelial cell differentiation glutathione derivative biosynthetic process glutathione metabolic process linoleic acid metabolic process prostaglandin metabolic process xenobiotic metabolic process | cytosol; extracellular exosome | fatty acid binding glutathione peroxidase activity glutathione transferase activity steroid delta-isomerase activity | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isomerase Lipid metabolism Oxidoreductase Peroxidase Reference proteome Transferase | MAEKPKLHYF | MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF | epithelial cell differentiation glutathione derivative biosynthetic process glutathione metabolic process linoleic acid metabolic process prostaglandin metabolic process xenobiotic metabolic process cytosol; extracellular exosome fatty acid binding glutathione peroxidase activity glutathione transferase activity steroi... |
bone mineralization calcium ion homeostasis cellular homeostasis cellular response to organic cyclic compound cementum mineralization dephosphorylation developmental process involved in reproduction endochondral ossification futile creatine cycle inhibition of non-skeletal tissue mineralization phosphate ion homeostasi... | extracellular matrix; extracellular membrane-bounded organelle; extracellular space; mitochondrial intermembrane space; mitochondrial membrane; plasma membrane; side of membrane | ADP phosphatase activity alkaline phosphatase activity ATP hydrolysis activity calcium ion binding inorganic diphosphate phosphatase activity phosphoamidase activity phosphoethanolamine phosphatase activity pyridoxal phosphatase activity pyrophosphatase activity | Rattus norvegicus | Biomineralization Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Mitochondrion Phosphoprotein Reference proteome Signal Zinc | MILPFLVLAI | MILPFLVLAIGTCLTNSFVPEKEKDPSYWRQQAQETLKNALKLQKLNTNVAKNIIMFLGDGMGVSTVTAARILKGQLHHNTGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYELDEKARGTRLDGLDLISIWKSFKPRHKHSHYVWNRTELLALDPSRVDYLLGLFEPGDMQYELNRNNLTDPSLSEMVEVALRIL... | bone mineralization calcium ion homeostasis cellular homeostasis cellular response to organic cyclic compound cementum mineralization dephosphorylation developmental process involved in reproduction endochondral ossification futile creatine cycle inhibition of non-skeletal tissue mineralization phosphate ion homeostasi... |
bone mineralization endocytosis glycoprotein metabolic process lipid homeostasis regulation of protein stability | endoplasmic reticulum quality control compartment; external side of plasma membrane; perinuclear region of cytoplasm | fucose binding mannose binding | Rattus norvegicus | Calcium Direct protein sequencing Disulfide bond Endocytosis Glycoprotein Lectin Lipoprotein Membrane Palmitate Phosphoprotein Receptor Reference proteome Signal-anchor Transmembrane Transmembrane helix | MEKDFQDIQQ | MEKDFQDIQQLDSEENDHQLIGDEEQGSHVQNLRTENPRWGGQPPSRPFPQRLCSKFRLSLLALAFNILLLVVICVVSSQSMQLQKEFWTLKETLSNFSTTTLMEFKALDSHGGSRNDNLTSWETILEKKQKDIKADHSTLLFHLKHFPLDLRTLTCQLAFFLSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQMENAHLLVINSREEQEFVVKHRGAFHIWIGLTDKDGSWKWVDGTEYRSNFKNWAFTQPDNWQGHEEGGSEDCAEILSDGLWNDNFCQQVNRWACERKRDITY | bone mineralization endocytosis glycoprotein metabolic process lipid homeostasis regulation of protein stability endoplasmic reticulum quality control compartment; external side of plasma membrane; perinuclear region of cytoplasm fucose binding mannose binding Rattus norvegicus Calcium Direct protein sequencing Disulfi... |
blood vessel diameter maintenance removal of superoxide radicals response to copper ion response to hypoxia | collagen-containing extracellular matrix; extracellular exosome; extracellular region; extracellular space; Golgi lumen | copper ion binding heparin binding molecular adaptor activity superoxide dismutase activity | Homo sapiens | 3D-structure Antioxidant Copper Direct protein sequencing Disulfide bond Glycation Glycoprotein Golgi apparatus Heparin-binding Metal-binding Oxidoreductase Reference proteome Secreted Signal Zinc | MLALLCSCLL | MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGDLSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA | blood vessel diameter maintenance removal of superoxide radicals response to copper ion response to hypoxia collagen-containing extracellular matrix; extracellular exosome; extracellular region; extracellular space; Golgi lumen copper ion binding heparin binding molecular adaptor activity superoxide dismutase activity ... |
arginine biosynthetic process via ornithine arginine catabolic process to ornithine arginine deiminase pathway citrulline biosynthetic process | cytoplasm | amino acid binding ornithine carbamoyltransferase activity | Pseudomonas aeruginosa | 3D-structure Arginine metabolism Cytoplasm Direct protein sequencing Reference proteome Transferase | MAFNMHNRNL | MAFNMHNRNLLSLMHHSTRELRYLLDLSRDLKRAKYTGTEQQHLKRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDPNSSQIGHKESMKDTARVLGRMYDAIEYRGFKQEIVEELAKFAGVPVFNGLTDEYHPTQMLADVLTMREHSDKPLHDISYAYLGDARNNMGNSLLLIGAKLGMDVRIAAPKALWPHDEFVAQCKKFAEESGAKLTLTEDPKEAVKGVDFVHTDVWVSMGEPVEAWGERIKELLPYQVNMEIMKATGNPRAKFMHCLPAFHNSETKVGKQIAEQYPNLANGIEVTEDVFESPYNIAFEQAEN... | arginine biosynthetic process via ornithine arginine catabolic process to ornithine arginine deiminase pathway citrulline biosynthetic process cytoplasm amino acid binding ornithine carbamoyltransferase activity Pseudomonas aeruginosa 3D-structure Arginine metabolism Cytoplasm Direct protein sequencing Reference proteo... |
angiotensin maturation antibacterial humoral response biofilm matrix disassembly cellular response to lipopolysaccharide cytokine-mediated signaling pathway defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium extracellular matrix disassembly immune response... | azurophil granule lumen; collagen-containing extracellular matrix; cytoplasm; cytoplasmic stress granule; cytosol; extracellular exosome; extracellular region; extracellular space; intracellular membrane-bounded organelle; lysosome; membrane; nucleus; plasma membrane; secretory granule | caspase binding heparin binding peptidase activity receptor ligand activity serine-type endopeptidase activity serine-type peptidase activity | Homo sapiens | 3D-structure Antibiotic Antimicrobial Cell membrane Chemotaxis Cytoplasm Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Membrane Nucleus Protease Reference proteome Secreted Serine protease Signal Zymogen | MQPLLLLLAF | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL | angiotensin maturation antibacterial humoral response biofilm matrix disassembly cellular response to lipopolysaccharide cytokine-mediated signaling pathway defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium extracellular matrix disassembly immune response... |
phenylalanyl-tRNA aminoacylation | cytoplasm; cytosol; phenylalanine-tRNA ligase complex | ATP binding magnesium ion binding phenylalanine-tRNA ligase activity tRNA binding | Escherichia coli | 3D-structure Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Magnesium Metal-binding Nucleotide-binding Protein biosynthesis Reference proteome | MSHLAELVAS | MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDL... | phenylalanyl-tRNA aminoacylation cytoplasm; cytosol; phenylalanine-tRNA ligase complex ATP binding magnesium ion binding phenylalanine-tRNA ligase activity tRNA binding Escherichia coli 3D-structure Aminoacyl-tRNA synthetase ATP-binding Cytoplasm Ligase Magnesium Metal-binding Nucleotide-binding Protein biosynthesis Re... |
angiogenesis antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide chemokine-mediated signaling pathway hemopoiesis inflammatory response leukocyte activation involved in inflammatory response leukocyte chemotaxis leukocyte chemotaxis involved in inflammatory re... | extracellular space | chemokine activity CXCR chemokine receptor binding cytokine activity growth factor activity | Gallus gallus | Chemotaxis Cytokine Disulfide bond Growth factor Reference proteome Secreted Signal | MNGKLGAVLA | MNGKLGAVLALLLVSAALSQGRTLVKMGNELRCQCISTHSKFIHPKSIQDVKLTPSGPHCKNVEIIATLKDGREVCLDPTAPWVQLIVKALMAKAQLNSDAPL | angiogenesis antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide chemokine-mediated signaling pathway hemopoiesis inflammatory response leukocyte activation involved in inflammatory response leukocyte chemotaxis leukocyte chemotaxis involved in inflammatory re... |
suppression by virus of host autophagy suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway | host cell cytoplasm; host cell nucleolus; virion component | protein serine/threonine phosphatase inhibitor activity | Human herpesvirus 1 | Host cytoplasm Host nucleus Host-virus interaction Inhibition of host autophagy by virus Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host RLR pathway by virus Modulation of host PP1 activity by virus Repeat Viral immunoevasion Virion Virulenc... | MARRRRHRGP | MARRRRHRGPRRPRPPGPTGAVPTAQSQVTSTPNSEPAVRSAPAAAPPPPPASGPPPSCSLLLRQWLHVPESASDDDDDDDWPDSPPPEPAPEARPTAAAPRPRSPPPGAGPGGGANPSHPPSRPFRLPPRLALRLRVTAEHLARLRLRRAGGEGAPEPPATPATPATPATPATPATPATPATPATPATPARVRFSPHVRVRHLVVWASAARLARRGSWARERADRARFRRRVAEAEAVIGPCLGPEARARALARGAGPANSV | suppression by virus of host autophagy suppression by virus of host translation initiation suppression by virus of host type I interferon-mediated signaling pathway host cell cytoplasm; host cell nucleolus; virion component protein serine/threonine phosphatase inhibitor activity Human herpesvirus 1 Host cytoplasm Hos... |
fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Cas-Br-E murine leukemia virus | Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host cell membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Palmitate Signal Transmembrane Transmembrane helix Viral atta... | MEGPAFSKSP | MEGPAFSKSPKDKTIERAFLGVLGILFVTGGLASRDNPHQVYNITWEVTNGEQDTVWAVTGNHPLWTWWPDLTPDLCMLALHGPTHWGLDNHPPYSSPPGPPCCSGDAGAVSGCARDCDEPLTSYSPRCNTAWNRLKLARVTHAPKEGFYICPGSHRPRWARSCGGLDAYYCASWGCETTGRAAWNPTSSWDYITVSNNLTSSQATKACKNNGWCNPLVIRFTGPGKRATSWTTGHFWGLRLYISGHDPGLTFGIRLKVTDLGPRVPIGPNPVLSDQRPPSRPVPARPPPPSASPSTPTIPPQQGTGDRLLNLVQGAYLT... | fusion of virus membrane with host plasma membrane viral entry into host cell virion attachment to host cell host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Cas-Br-E murine leukemia virusCleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with ho... |
proteolysis | host cell cytoplasm; T=13 icosahedral viral capsid | metal ion binding serine-type peptidase activity structural molecule activity | Avian infectious bursal disease virus | Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion | MTNLSDQTQQ | MTNLSDQTQQIVPFIRSLLMPTTGPASIPDDTLEKHTLRSETSTYNLTVGDTGSGLIVFFPGFPGSIVGAHYTMQSNGNYKFDQMLLTAQNLPASYNYCRLVSRSLTVRSSTLPGGVYALNGTINAVTFQGSLSELTDVSYNGLMSATANINDKIGNVLVGEGVTVLSLPTSYDLGYVRLGDPIPAIGLDPKMVATCDSSDRPRVYTITAADDYQFSSQYQPGGVTITLFSANIDAITNLSVGGELVFQTSVQGLVLNATIYLVGFDGTTVTTRAVAAGNGLTAGTDNLMPFNLVIPTSEITQPVTSIKLEIVTSKSGGQ... | proteolysis host cell cytoplasm; T=13 icosahedral viral capsid metal ion binding serine-type peptidase activity structural molecule activity Avian infectious bursal disease virus Capsid protein Host cytoplasm Hydrolase Metal-binding Protease Serine protease T=13 icosahedral capsid protein Virion MTNLSDQTQQ MTNLSDQTQQ... |
cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape | cytoplasm; cytosol | FAD binding flavin adenine dinucleotide binding UDP-N-acetylmuramate dehydrogenase activity | Escherichia coli | 3D-structure Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Cytoplasm FAD Flavoprotein NADP Oxidoreductase Peptidoglycan synthesis Reference proteome | MNHSLKPWNT | MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNV... | cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape cytoplasm; cytosol FAD binding flavin adenine dinucleotide binding UDP-N-acetylmuramate dehydrogenase activity Escherichia coli 3D-structure Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Cy... |
modulation by symbiont of host protein ubiquitination peturbation by virus of host exit from mitosis positive regulation of protein catabolic process protein polyubiquitination release from viral latency response to type I interferon suppression by virus of host type I interferon production suppression by virus of host... | host cell cytoplasm; host cell nucleus; viral tegument | DNA binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity | Human herpesvirus 1 | 3D-structure Activator DNA-binding Early protein Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host IRF3 by virus Inhibition of host mitotic exit by virus Inhibition of host RLR pathway by virus Metal-binding Modulation of host cell cycle by virus Mo... | MEPRPGASTR | MEPRPGASTRRPEGRPQREPAPDVWVFPCDRDLPDSSDSEAETEVGGRGDADHHDDDSASEADSTDTELFETGLLGPQGVDGGAVSGGSPPREEDPGSCGGAPPREDGGSDEGDVCAVCTDEIAPHLRCDTFPCMHRFCIPCMKTWMQLRNTCPLCNAKLVYLIVGVTPSGSFSTIPIVNDPQTRMEAEEAVRAGTAVDFIWTGNQRFAPRYLTLGGHTVRALSPTHPEPTTDEDDDDLDDADYVPPAPRRTPRAPPRRGAAAPPVTGGASHAAPQPAAARTAPPSAPIGPHGSSNTNTTTNSSGGGGSRQSRAAAPRGA... | modulation by symbiont of host protein ubiquitination peturbation by virus of host exit from mitosis positive regulation of protein catabolic process protein polyubiquitination release from viral latency response to type I interferon suppression by virus of host type I interferon production suppression by virus of host... |
signal peptide processing | membrane; plasma membrane | endopeptidase activity serine-type peptidase activity | Escherichia coli | 3D-structure Cell inner membrane Cell membrane Hydrolase Membrane Protease Reference proteome Serine protease Transmembrane Transmembrane helix | MRTLWRFIAG | MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQVSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVNTIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQYYLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRDDMSPAAREADSRWIGELWQNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKYALENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDYALKT... | signal peptide processing membrane; plasma membrane endopeptidase activity serine-type peptidase activity Escherichia coli 3D-structure Cell inner membrane Cell membrane Hydrolase Membrane Protease Reference proteome Serine protease Transmembrane Transmembrane helix MRTLWRFIAG MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIW... |
heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process protoporphyrinogen IX biosynthetic process | cytoplasm; cytosol | hydroxymethylbilane synthase activity | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Disease variant Heme biosynthesis Phosphoprotein Porphyrin biosynthesis Reference proteome Transferase | MSGNGNAAAT | MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVGITA... | heme A biosynthetic process heme B biosynthetic process heme biosynthetic process heme O biosynthetic process protoporphyrinogen IX biosynthetic process cytoplasm; cytosol hydroxymethylbilane synthase activity Homo sapiens 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Disease variant... |
activation of meiosis involved in egg activation apoptotic signaling pathway calcium ion transport cell differentiation cell projection morphogenesis cellular response to homocysteine G1/S transition of mitotic cell cycle hippocampal neuron apoptotic process long-term synaptic potentiation nervous system development ne... | calcium- and calmodulin-dependent protein kinase complex; centrosome; cytoplasm; cytosol; dendrite; glutamatergic synapse; neuron projection; perikaryon; postsynaptic density; sarcoplasmic reticulum membrane; spindle midzone | ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity identical protein binding phospholipase binding protein homodimerization activity protein kinase binding protein serine kinase activity protein serine/threonine kinase activity structur... | Rattus norvegicus | 3D-structure ATP-binding Calmodulin-binding Cytoplasm Cytoskeleton Differentiation Kinase Membrane Neurogenesis Nucleotide-binding Phosphoprotein Reference proteome Sarcoplasmic reticulum Serine/threonine-protein kinase Synapse Transferase | MATTVTCTRF | MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSVGRQT... | activation of meiosis involved in egg activation apoptotic signaling pathway calcium ion transport cell differentiation cell projection morphogenesis cellular response to homocysteine G1/S transition of mitotic cell cycle hippocampal neuron apoptotic process long-term synaptic potentiation nervous system development ne... |
adaptive immune response inflammatory response intracellular signal transduction long-term memory myeloid dendritic cell differentiation neuron-neuron synaptic transmission nucleocytoplasmic transport phosphorylation positive regulation of DNA-templated transcription positive regulation of protein export from nucleus p... | cytoplasm; cytosol; fibrillar center; GABA-ergic synapse; glutamatergic synapse; nucleoplasm; nucleus; postsynapse | ATP binding calcium-dependent protein serine/threonine kinase activity calmodulin binding calmodulin-dependent protein kinase activity protein serine kinase activity | Mus musculus | Adaptive immunity ATP-binding Calcium Calmodulin-binding Cytoplasm Glycoprotein Immunity Inflammatory response Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Serine/threonine-protein kinase Transferase | MLKVTVPSCP | MLKVTVPSCPSSPCSSVTASTENLVPDYWIDGSNRDPLGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARR... | adaptive immune response inflammatory response intracellular signal transduction long-term memory myeloid dendritic cell differentiation neuron-neuron synaptic transmission nucleocytoplasmic transport phosphorylation positive regulation of DNA-templated transcription positive regulation of protein export from nucleus p... |
DNA damage response double-strand break repair fumarate metabolic process malate metabolic process tricarboxylic acid cycle | cytosol; mitochondrial matrix; mitochondrion; nucleus; tricarboxylic acid cycle enzyme complex | fumarate hydratase activity | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing DNA damage DNA repair Lyase Mitochondrion Nucleus Phosphoprotein Reference proteome Transit peptide Tricarboxylic acid cycle | MLRFTNCSCK | MLRFTNCSCKTFVKSSYKLNIRRMNSSFRTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDPKISKAIQQAADEVASGKLDDHFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQVHPNNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAAHDAIVECSGALNTLACSLFKIAQDI... | DNA damage response double-strand break repair fumarate metabolic process malate metabolic process tricarboxylic acid cycle cytosol; mitochondrial matrix; mitochondrion; nucleus; tricarboxylic acid cycle enzyme complex fumarate hydratase activity Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencin... |
insulin catabolic process proteolysis regulation of insulin secretion regulation of platelet aggregation response to insulin | extracellular region; extracellular space | endopeptidase activity serine-type endopeptidase activity | Sus scrofa | 3D-structure Disulfide bond Hydrolase Protease Reference proteome Secreted Serine protease Signal Zymogen | MIRALLLSTL | MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN | insulin catabolic process proteolysis regulation of insulin secretion regulation of platelet aggregation response to insulin extracellular region; extracellular space endopeptidase activity serine-type endopeptidase activity Sus scrofa 3D-structure Disulfide bond Hydrolase Protease Reference proteome Secreted Serine pr... |
amyloid-beta metabolic process angiotensin maturation cell maturation cellular response to xenobiotic stimulus drinking behavior hormone-mediated signaling pathway juxtaglomerular apparatus development kidney development male gonad development mesonephros development proteolysis regulation of blood pressure regulation ... | apical part of cell; extracellular space; membrane | aspartic-type endopeptidase activity endopeptidase activity insulin-like growth factor receptor binding peptidase activity signaling receptor binding | Rattus norvegicus | 3D-structure Aspartyl protease Cleavage on pair of basic residues Disulfide bond Glycoprotein Hydrolase Membrane Protease Reference proteome Secreted Signal Zymogen | MGGRRMPLWA | MGGRRMPLWALLLLWTSCSFSLPTDTASFGRILLKKMPSVREILEERGVDMTRISAEWGEFIKKSSFTNVTSPVVLTNYLDTQYYGEIGIGTPSQTFKVIFDTGSANLWVPSTKCGPLYTACEIHNLYDSSESSSYMENGTEFTIHYGSGKVKGFLSQDVVTVGGIIVTQTFGEVTELPLIPFMLAKFDGVLGMGFPAQAVDGVIPVFDHILSQRVLKEEVFSVYYSRESHLLGGEVVLGGSDPQHYQGNFHYVSISKAGSWQITMKGVSVGPATLLCEEGCMAVVDTGTSYISGPTSSLQLIMQALGVKEKRANNYVVN... | amyloid-beta metabolic process angiotensin maturation cell maturation cellular response to xenobiotic stimulus drinking behavior hormone-mediated signaling pathway juxtaglomerular apparatus development kidney development male gonad development mesonephros development proteolysis regulation of blood pressure regulation ... |
mitochondrial phenylalanyl-tRNA aminoacylation phenylalanyl-tRNA aminoacylation | cytoplasm; mitochondrial matrix; mitochondrion | ATP binding phenylalanine-tRNA ligase activity tRNA binding | Saccharomyces cerevisiae | Aminoacyl-tRNA synthetase ATP-binding Ligase Mitochondrion Nucleotide-binding Protein biosynthesis Reference proteome Transit peptide | MFLNRMMKTR | MFLNRMMKTRTGLYRLYSTLKVPHVEINGIKYKTDPQTTNVTDSIIKLTDRSLHLKESHPVGILRDLIEKKLNSVDNTFKIFNNFKPVVTTMENFDSLGFPKDHPGRSKSDTYYINETHLLRTHTSAHELECFQKIRNDSDNIKSGFLISADVYRRDEIDKTHYPVFHQMEGATIWKRTKADVGVKEPMYIEKIREDIRQVENLLNKENVKITVDDDTIPLKENNPKQEYMSDLEVDLCSQHLKRSIELIVSEVFNKKISSMIKNKANNTPKELKVRWINAYFPWTAPSWEIEVWWQGEWLELCGCGLIRQDVLLRAGYK... | mitochondrial phenylalanyl-tRNA aminoacylation phenylalanyl-tRNA aminoacylation cytoplasm; mitochondrial matrix; mitochondrion ATP binding phenylalanine-tRNA ligase activity tRNA binding Saccharomyces cerevisiae Aminoacyl-tRNA synthetase ATP-binding Ligase Mitochondrion Nucleotide-binding Protein biosynthesis Referenc... |
cellular response to mechanical stimulus cellular response to nitric oxide circadian rhythm opsonization positive regulation of phagocytosis respiratory gaseous exchange by respiratory system response to epidermal growth factor response to glucocorticoid response to hormone response to hyperoxia response to hypoxia res... | collagen trimer; extracellular space; multivesicular body | carbohydrate binding metal ion binding | Rattus norvegicus | 3D-structure Calcium Collagen Direct protein sequencing Disulfide bond Extracellular matrix Gaseous exchange Glycoprotein Hydroxylation Lectin Metal-binding Reference proteome Repeat Secreted Signal Surface film | MSLCSLAFTL | MSLCSLAFTLFLTVVAGIKCNVTDVCAGSPGIPGAPGNHGLPGRDGRDGVKGDPGPPGPMGPPGGMPGLPGRDGLPGAPGAPGERGDKGEPGERGLPGFPAYLDEELQTELYEIKHQILQTMGVLSLQGSMLSVGDKVFSTNGQSVNFDTIKEMCTRAGGNIAVPRTPEENEAIASIAKKYNNYVYLGMIEDQTPGDFHYLDGASVNYTNWYPGEPRGQGKEKCVEMYTDGTWNDRGCLQYRLAVCEF | cellular response to mechanical stimulus cellular response to nitric oxide circadian rhythm opsonization positive regulation of phagocytosis respiratory gaseous exchange by respiratory system response to epidermal growth factor response to glucocorticoid response to hormone response to hyperoxia response to hypoxia res... |
4-chlorobiphenyl metabolic process cellular glucuronidation cellular response to glucocorticoid stimulus cellular response to hormone stimulus liver development response to lipopolysaccharide response to organic cyclic compound response to peptide hormone xenobiotic metabolic process | endoplasmic reticulum; endoplasmic reticulum membrane; protein-containing complex | enzyme binding glucuronosyltransferase activity protein homodimerization activity protein-containing complex binding | Rattus norvegicus | Alternative splicing Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Microsome Phosphoprotein Reference proteome Signal Transferase Transmembrane Transmembrane helix | MACLLPAARL | MACLLPAARLPAGFLFLVLWGSVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHDIVVLVPEVNLLLGESKYYRRKSFPVPYNLEELRTRYRSFGNNHFAASSPLMAPLREYRNNMIVIDMCFFSCQSLLKDSATLSFLRENQFDALFTDPAMPCGVILAEYLKLPSIYLFRGFPCSLEHIGQSPSPVSYVPRFYTKFSDHMTFPQRLANFIANILENYLYHCLYSKYEILASDLLKRDVSLPALHQNSLWLLRYDFVFEYPRPVMPNMIFIGGTNCKKKGNLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAE... | 4-chlorobiphenyl metabolic process cellular glucuronidation cellular response to glucocorticoid stimulus cellular response to hormone stimulus liver development response to lipopolysaccharide response to organic cyclic compound response to peptide hormone xenobiotic metabolic process endoplasmic reticulum; endoplasmic ... |
pantothenate biosynthetic process putrescine biosynthetic process putrescine biosynthetic process from ornithine | cytoplasm | ornithine decarboxylase activity | Saccharomyces cerevisiae | Cytoplasm Decarboxylase Lyase Polyamine biosynthesis Pyridoxal phosphate Reference proteome | MSSTQVGNAL | MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDGETLHNLLLELKNNQDLELLPHEQAHPKIFQALKARIGRINNETCDPGEENSFFICDLGEVKRLFNNWVKELPRIKPFYAVKCNPDTKVLSLLAELGVNFDCASKVEIDRVLSMNISPDRIVYANPCKVASFIRYAASKNVMKSTFDNVEELHKIKKFHPESQLLLRIATDDSTAQCRLSTKYGCEMENVDVLLKAIKELGLNLAGVSFHVGSGASDFTSLYKAVRDARTVFDKAANEYGLPPLKILDVGGGFQFESFKESTAVLRLALEEFFPVGCGVDIIAEPG... | pantothenate biosynthetic process putrescine biosynthetic process putrescine biosynthetic process from ornithine cytoplasm ornithine decarboxylase activity Saccharomyces cerevisiae Cytoplasm Decarboxylase Lyase Polyamine biosynthesis Pyridoxal phosphate Reference proteome MSSTQVGNAL MSSTQVGNALSSSTTTLVDLSNSTVTQKKQYYKDG... |
induction by virus of host autophagy protein complex oligomerization virus-mediated pore formation in host cell membrane | extracellular region; host caveola; host cell rough endoplasmic reticulum membrane; membrane | metal ion binding monoatomic ion channel activity toxin activity | Rotavirus A ) | 3D-structure Activation of host autophagy by virus Calcium Enterotoxin Glycoprotein Host endoplasmic reticulum Host membrane Host-virus interaction Ion channel Ion transport Membrane Metal-binding Secreted Signal-anchor Toxin Transmembrane Transmembrane helix Transport Viral ion channel Virulence | MEKLTDLNYT | MEKLTDLNYTSSVITLMNSTLHTILEDPGMAYFPYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVVKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRQLEMIDKLTTREIEQVELLKRIHDKLMIRAVDEIDMTKEINQKNVRTLEEWENGKNPYEPKEVTAAM | induction by virus of host autophagy protein complex oligomerization virus-mediated pore formation in host cell membrane extracellular region; host caveola; host cell rough endoplasmic reticulum membrane; membrane metal ion binding monoatomic ion channel activity toxin activity Rotavirus A )3D-structure Activation of... |
ascospore formation ascospore wall assembly meiotic spindle disassembly negative regulation of protein localization to nucleolus phosphorylation positive regulation of ascospore-type prospore membrane formation | cytoplasm; nucleus; prospore membrane | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Saccharomyces cerevisiae | ATP-binding Cytoplasm Kinase Meiosis Nucleotide-binding Nucleus Reference proteome Serine/threonine-protein kinase Sporulation Transferase | MESKEISIRS | MESKEISIRSRTPPSKLYSIQSCIGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDEDIELLAQEIFFLAELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKRDTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKDFVAGCLVKTPADRPSAYNLLSFEFVKNITITNLKSDVDLIKQKKVQERYTKVPKYPLQNRLYKNSNTVRGKEF... | ascospore formation ascospore wall assembly meiotic spindle disassembly negative regulation of protein localization to nucleolus phosphorylation positive regulation of ascospore-type prospore membrane formation cytoplasm; nucleus; prospore membrane ATP binding protein kinase activity protein serine kinase activity prot... |
cell-matrix adhesion extracellular matrix organization glomerular basement membrane development positive regulation of cell-substrate adhesion | basement membrane; cell periphery; extracellular matrix; extracellular region | collagen binding extracellular matrix binding laminin binding laminin-1 binding proteoglycan binding | Rattus norvegicus | Basement membrane Cell adhesion Disulfide bond EGF-like domain Extracellular matrix Glycoprotein Reference proteome Secreted Sulfation | EFHPGTFPPS | EFHPGTFPPSFGSVAPFLADLDTTDGLGNVYYREDLSPFIIQMAAEYVQRGFPEVSFQPTSVVVVTWESMAPYGGPSGSLVEEGKRNTFQAVLASSNSSSYAIFLYPDDGLQFFTTFSKKDENQVPAVVGFSKGLEGFLWKSNGAYNIFANDRESIENLAKSSNAGHQGVWVFEIGSPATAKGVVPADVNLDVDDDGADYEDEDYDLQTSHLGLEDVATQPFPSHSPRRGYPDPHNVPRTLAPSYEATERPHGIPTERTKSFQLPVERFPQKHPQVIDVDEVEETGVVFSYNTGSQQTCANNRHQCSVHAECRDYATGFC... | cell-matrix adhesion extracellular matrix organization glomerular basement membrane development positive regulation of cell-substrate adhesion basement membrane; cell periphery; extracellular matrix; extracellular region collagen binding extracellular matrix binding laminin binding laminin-1 binding proteoglycan bindin... |
acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle | mitochondrial matrix; mitochondrial pyruvate dehydrogenase complex; mitochondrion; pyruvate dehydrogenase complex | acetyltransferase activity dihydrolipoyllysine-residue acetyltransferase activity identical protein binding nucleotide binding | Rattus norvegicus | Acetylation Acyltransferase Carbohydrate metabolism Direct protein sequencing Glucose metabolism Lipoyl Mitochondrion Phosphoprotein Reference proteome Repeat Transferase Transit peptide Tricarboxylic acid cycle | MWRVCARRVQ | MWRVCARRVQSAVPRAGFRARWATLKGPRTGPAAVRCGSGIPSYGVRSLCGWSYGSATVPRNRILQQLLGSPSRRSYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGEKISEGDLIAEVETDKATVGFESLEECYMAKILVPEGTRDVPVGSIICITVEKPQDIEAFKNYTLDSATAATQAAPAPAAAPAAAPAAPSASAPGSSYPVHMQIVLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKQEDIAAFADYRPTEVTSLKPQAPPPVPPPVAAVP... | acetyl-CoA biosynthetic process from pyruvate glucose metabolic process tricarboxylic acid cycle mitochondrial matrix; mitochondrial pyruvate dehydrogenase complex; mitochondrion; pyruvate dehydrogenase complex acetyltransferase activity dihydrolipoyllysine-residue acetyltransferase activity identical protein binding n... |
cell cycle cell division regulation of mitotic cell cycle signaling | cyclin-dependent protein kinase holoenzyme complex; cytosol; nucleus; SCF ubiquitin ligase complex | cyclin-dependent protein serine/threonine kinase activator activity histone binding protein kinase binding protein-containing complex binding ubiquitin binding zinc ion binding | Schizosaccharomyces pombe | 3D-structure Cell cycle Cell division Direct protein sequencing Reference proteome | MSKSGVPRLL | MSKSGVPRLLTASERERLEPFIDQIHYSPRYADDEYEYRHVMLPKAMLKAIPTDYFNPETGTLRILQEEEWRGLGITQSLGWEMYEVHVPEPHILLFKREKDYQMKFSQQRGG | cell cycle cell division regulation of mitotic cell cycle signaling cyclin-dependent protein kinase holoenzyme complex; cytosol; nucleus; SCF ubiquitin ligase complex cyclin-dependent protein serine/threonine kinase activator activity histone binding protein kinase binding protein-containing complex binding ubiquitin b... |
apoptotic DNA fragmentation apoptotic process defense response to virus DNA catabolic process DNA recombination RNA catabolic process | cytosol; mitochondrial inner membrane; mitochondrion; nucleus | DNA endonuclease activity DNA exonuclease activity metal ion binding nucleic acid binding RNA endonuclease activity RNA nuclease activity single-stranded DNA endodeoxyribonuclease activity | Saccharomyces cerevisiae | Endonuclease Hydrolase Magnesium Manganese Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Nuclease Reference proteome | MCSRILLSGL | MCSRILLSGLVGLGAGTGLTYLLLNKHSPTQIIETPYPPTQKPNSNIQSHSFNVDPSGFFKYGFPGPIHDLQNREEFISCYNRQTQNPYWVLEHITPESLAARNADRKNSFFKEDEVIPEKFRGKLRDYFRSGYDRGHQAPAADAKFSQQAMDDTFYLSNMCPQVGEGFNRDYWAHLEYFCRGLTKKYKSVRIVTGPLYLPKKDPIDNKFRVNYEVIGNPPSIAVPTHFFKLIVAEAPTANPAREDIAVAAFVLPNEPISNETKLTDFEVPIDALERSTGLELLQKVPPSKKKALCKEVNCQIVVRDFSNAAIKQSKDVK... | apoptotic DNA fragmentation apoptotic process defense response to virus DNA catabolic process DNA recombination RNA catabolic process cytosol; mitochondrial inner membrane; mitochondrion; nucleus DNA endonuclease activity DNA exonuclease activity metal ion binding nucleic acid binding RNA endonuclease activity RNA nucl... |
amyloid-beta clearance amyloid-beta clearance by cellular catabolic process amyloid-beta metabolic process bradykinin catabolic process cellular response to cytokine stimulus cellular response to UV-A cellular response to UV-B creatinine metabolic process hormone catabolic process kidney development learning or memory ... | axon; brush border; cell surface; cytoplasm; cytoplasmic vesicle; dendrite; early endosome; extracellular exosome; focal adhesion; membrane; membrane raft; neuron projection terminus; neuronal cell body; plasma membrane; presynapse; secretory granule membrane; synapse; synaptic vesicle; trans-Golgi network | cardiolipin binding endopeptidase activity exopeptidase activity metalloendopeptidase activity oligopeptidase activity peptide binding phosphatidylserine binding protein homodimerization activity zinc ion binding | Homo sapiens | 3D-structure Cell membrane Charcot-Marie-Tooth disease Disease variant Disulfide bond Glycoprotein Hydrolase Lipoprotein Membrane Metal-binding Metalloprotease Myristate Neurodegeneration Neuropathy Phosphoprotein Protease Reference proteome Signal-anchor Spinocerebellar ataxia Transmembrane Transmembrane helix Zinc | MGKSESQMDI | MGKSESQMDITDINTPKPKKKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKP... | amyloid-beta clearance amyloid-beta clearance by cellular catabolic process amyloid-beta metabolic process bradykinin catabolic process cellular response to cytokine stimulus cellular response to UV-A cellular response to UV-B creatinine metabolic process hormone catabolic process kidney development learning or memory ... |
peptide metabolic process | transport vesicle membrane | copper ion binding peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity | Xenopus laevis | Alternative splicing Copper Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Lyase Membrane Metal-binding Monooxygenase Multifunctional enzyme Oxidoreductase Reference proteome Repeat Signal Transmembrane Transmembrane helix Zinc | MASLSSSFLV | MASLSSSFLVLFLLFQNSCYCFRSPLSVFKRYEESTRSLSNDCLGTTRPVMSPGSSDYTLDIRMPGVTPTESDTYLCKSYRLPVDDEAYVVDFRPHANMDTAHHMLLFGCNIPSSTDDYWDCSAGTCMDKSSIMYAWAKNAPPTKLPEGVGFRVGGKSGSRYFVLQVHYGNVKAFQDKHKDCTGVTVRVTPEKQPQIAGIYLSMSVDTVIPPGEEAVNSDIACLYNRPTIHPFAYRVHTHQLGQVVSGFRVRHGKWSLIGRQSPQLPQAFYPVEHPVEISPGDIIATRCLFTGKGRTSATYIGGTSNDEMCNLYIMYYMD... | peptide metabolic process transport vesicle membrane copper ion binding peptidylamidoglycolate lyase activity peptidylglycine monooxygenase activity Xenopus laevis Alternative splicing Copper Cytoplasmic vesicle Direct protein sequencing Disulfide bond Glycoprotein Lyase Membrane Metal-binding Monooxygenase Multifuncti... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission cognition G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger neuromuscular synaptic transmission posi... | asymmetric synapse; axon terminus; cholinergic synapse; dendrite; glutamatergic synapse; postsynaptic density membrane; postsynaptic membrane; presynaptic membrane; Schaffer collateral - CA1 synapse; synapse | G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity | Rattus norvegicus | Cell membrane Direct protein sequencing Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MNTSVPPAVS | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDSEAQAPTKQPPK... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission cognition G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger neuromuscular synaptic transmission posi... |
acetylcholine receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway calcium-mediated signaling chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide... | asymmetric synapse; axon terminus; basal plasma membrane; basolateral plasma membrane; dendrite; endoplasmic reticulum membrane; glutamatergic synapse; plasma membrane; postsynaptic density membrane; presynaptic membrane; synapse | acetylcholine binding G protein-coupled acetylcholine receptor activity G protein-coupled acetylcholine receptor binding G protein-coupled serotonin receptor activity quaternary ammonium group binding | Rattus norvegicus | 3D-structure Cell membrane Direct protein sequencing Disulfide bond Endoplasmic reticulum G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MTLHSNSTTS | MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVTQLGSYNISQETGNFSSNDTSSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGVKRSSRRKYGRCHFWFTTKSWK... | acetylcholine receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway calcium-mediated signaling chemical synaptic transmission G protein-coupled acetylcholine receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide... |
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of locomotion response to organic substance | asymmetric synapse; axon terminus; dendrite; glutamatergic synapse; membrane; neuronal cell body; postsynaptic density membrane; presynaptic membrane; synapse | G protein-coupled acetylcholine receptor activity G protein-coupled serotonin receptor activity guanyl-nucleotide exchange factor activity | Rattus norvegicus | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Synapse Transducer Transmembrane Transmembrane helix | MXNFTPVNGS | MXNFTPVNGSSANQSVRLVTAAHNHLETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLGCADLIIGAFSMNLYTLYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKPSIKKPPPGGASREELRNGKLEEAPPPALPPPPRPVPDKDTSNESSSGSATQNTKERPPTELSTAEATTP... | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger regulation of locomotion response to organic substance asymmetric synapse; axon terminus; dendrite; glutamate... |
cartilage condensation cell differentiation ossification regulation of bone mineralization | collagen-containing extracellular matrix; extracellular exosome; extracellular matrix | calcium ion binding extracellular matrix structural constituent structural constituent of bone | Homo sapiens | Alternative splicing Chondrogenesis Deafness Developmental protein Differentiation Direct protein sequencing Disulfide bond Gamma-carboxyglutamic acid Osteogenesis Phosphoprotein Reference proteome Secreted Signal | MKSLILLAIL | MKSLILLAILAALAVVTLCYESHESMESYELNPFINRRNANTFISPQQRWRAKVQERIRERSKPVHELNREACDDYRLCERYAMVYGYNAAYNRYFRKRRGTK | cartilage condensation cell differentiation ossification regulation of bone mineralization collagen-containing extracellular matrix; extracellular exosome; extracellular matrix calcium ion binding extracellular matrix structural constituent structural constituent of bone Homo sapiens Alternative splicing Chondrogenesis... |
branching morphogenesis of an epithelial tube cartilage development cell differentiation lung development ossification protein-containing complex assembly regulation of bone mineralization response to calcium ion response to glucocorticoid response to hormone response to mechanical stimulus response to nutrient respons... | collagen-containing extracellular matrix; extracellular matrix; extracellular space; protein-containing complex | calcium ion binding calcium-dependent protein binding | Rattus norvegicus | Chondrogenesis Developmental protein Differentiation Disulfide bond Gamma-carboxyglutamic acid Osteogenesis Phosphoprotein Reference proteome Secreted Signal | MKSLLPLAIL | MKSLLPLAILAALAVAALCYESHESMESYEVSPFTTRRNANTFISPQQRWHAKAQERVRELNKPAQEINREACDDYKLCERYALIYGYNAAYNRYFRQRRGAK | branching morphogenesis of an epithelial tube cartilage development cell differentiation lung development ossification protein-containing complex assembly regulation of bone mineralization response to calcium ion response to glucocorticoid response to hormone response to mechanical stimulus response to nutrient respons... |
diaminopimelate biosynthetic process homoserine biosynthetic process lysine biosynthetic process via diaminopimelate phosphorylation threonine biosynthetic process | cytosol | aspartate kinase activity ATP binding | Bacillus subtilis | Alternative initiation Amino-acid biosynthesis ATP-binding Diaminopimelate biosynthesis Kinase Lysine biosynthesis Nucleotide-binding Reference proteome Repeat Transferase | MGLIVQKFGG | MGLIVQKFGGTSVGSVEKIQNAANRAIAEKQKGHQVVVVVSAMGKSTDELVSLAKAISDQPSKREMDMLLATGEQVTISLLSMALQEKGYDAVSYTGWQAGIRTEAIHGNARITDIDTSVLADQLEKGKIVIVAGFQGMTEDCEITTLGRGGSDTTAVALAAALKADKCDIYTDVPGVFTTDPRYVKSARKLEGISYDEMLELANLGAGVLHPRAVEFAKNYQVPLEVRSSTETEAGTLIEEESSMEQNLIVRGIAFEDQITRVTIYGLTSGLTTLSTIFTTLAKRNINVDIIIQTQAEDKTGISFSVKTEDADQTVAVL... | diaminopimelate biosynthetic process homoserine biosynthetic process lysine biosynthetic process via diaminopimelate phosphorylation threonine biosynthetic process cytosol aspartate kinase activity ATP binding Bacillus subtilis Alternative initiation Amino-acid biosynthesis ATP-binding Diaminopimelate biosynthesis Kina... |
cardiac muscle cell differentiation carnitine biosynthetic process carnitine metabolic process carnitine metabolic process, CoA-linked fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase glycogen biosynthetic process heart development liver development medium-chain fatty acid catabolic proc... | axon; cytoplasm; mitochondrial matrix; mitochondrial membrane; mitochondrion | acyl-CoA dehydrogenase activity fatty-acyl-CoA binding flavin adenine dinucleotide binding identical protein binding isomerase activity medium-chain-acyl-CoA dehydrogenase activity | Rattus norvegicus | Acetylation Direct protein sequencing FAD Fatty acid metabolism Flavoprotein Lipid metabolism Mitochondrion Oxidoreductase Phosphoprotein Reference proteome Transit peptide | MAAALRRGYK | MAAALRRGYKVLRSVSHFECRAQHTKPSLKQEPGLGFSFELTEQQKEFQTIARKFAREEIIPVAPDYDKSGEYPFPLIKRAWELGLINTHIPESCGGLGLGTFDACLITEELAYGCTGVQTAIEANSLGQMPVIIAGNDQQKKKYLGRMTEQPMMCAYCVTEPSAGSDVAGIKTKAEKKGDEYVINGQKMWITNGGKANWYFVLTRSNPDPKVPASKAFTGFIVEADTPGIHIGKKELNMGQRCSDTRGITFEDVRVPKENVLIGEGAGFKIAMGAFDRTRPTVAAGAVGLAQRALDEATKYALDRKTFGKLLVEHQGVS... | cardiac muscle cell differentiation carnitine biosynthetic process carnitine metabolic process carnitine metabolic process, CoA-linked fatty acid beta-oxidation fatty acid beta-oxidation using acyl-CoA dehydrogenase glycogen biosynthetic process heart development liver development medium-chain fatty acid catabolic proc... |
cell wall organization peptidoglycan biosynthetic process proteolysis regulation of cell shape response to xenobiotic stimulus | outer membrane-bounded periplasmic space; plasma membrane | carboxypeptidase activity penicillin binding protein homodimerization activity serine-type D-Ala-D-Ala carboxypeptidase activity | Escherichia coli | 3D-structure Carboxypeptidase Cell inner membrane Cell membrane Cell shape Cell wall biogenesis/degradation Direct protein sequencing Hydrolase Membrane Peptidoglycan synthesis Protease Reference proteome Signal | MTQYSSLLRG | MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSV... | cell wall organization peptidoglycan biosynthetic process proteolysis regulation of cell shape response to xenobiotic stimulus outer membrane-bounded periplasmic space; plasma membrane carboxypeptidase activity penicillin binding protein homodimerization activity serine-type D-Ala-D-Ala carboxypeptidase activity Escher... |
antibody-dependent cellular cytotoxicity antigen processing and presentation of exogenous peptide antigen via MHC class I cell surface receptor signaling pathway mast cell activation neutrophil chemotaxis phagocytosis, engulfment phagocytosis, recognition positive regulation of phagocytosis positive regulation of tumor... | cell surface; external side of plasma membrane | IgG binding IgG receptor activity immunoglobulin receptor binding transmembrane signaling receptor activity | Mus musculus | Cell membrane Disulfide bond Glycoprotein IgG-binding protein Immunoglobulin domain Membrane Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MFQNAHSGSQ | MFQNAHSGSQWLLPPLTILLLFAFADRQSAALPKAVVKLDPPWIQVLKEDMVTLMCEGTHNPGNSSTQWFHNGRSIRSQVQASYTFKATVNDSGEYRCQMEQTRLSDPVDLGVISDWLLLQTPQRVFLEGETITLRCHSWRNKLLNRISFFHNEKSVRYHHYKSNFSIPKANHSHSGDYYCKGSLGSTQHQSKPVTITVQDPATTSSISLVWYHTAFSLVMCLLFAVDTGLYFYVRRNLQTPREYWRKSLSIRKHQAPQDK | antibody-dependent cellular cytotoxicity antigen processing and presentation of exogenous peptide antigen via MHC class I cell surface receptor signaling pathway mast cell activation neutrophil chemotaxis phagocytosis, engulfment phagocytosis, recognition positive regulation of phagocytosis positive regulation of tumor... |
action potential axon extension behavioral response to ether cellular response to dopamine courtship behavior detection of visible light larval locomotory behavior learning or memory mating behavior, sex discrimination positive regulation of circadian sleep/wake cycle, sleep positive regulation of membrane potential po... | membrane; voltage-gated potassium channel complex | delayed rectifier potassium channel activity voltage-gated monoatomic cation channel activity voltage-gated potassium channel activity | Drosophila melanogaster | 3D-structure Alternative splicing Behavior Cell membrane Glycoprotein Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Reference proteome RNA editing Transmembrane Transmembrane helix Transport Voltage-gated channel | MAAVAGLYGL | MAAVAGLYGLGEDRQHRKKQQQQQQHQKEQLEQKEEQKKIAERKLQLREQQLQRNSLDGYGSLPKLSSQDEEGGAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAI... | action potential axon extension behavioral response to ether cellular response to dopamine courtship behavior detection of visible light larval locomotory behavior learning or memory mating behavior, sex discrimination positive regulation of circadian sleep/wake cycle, sleep positive regulation of membrane potential po... |
arachidonic acid metabolic process icosanoid biosynthetic process kidney development lauric acid metabolic process linoleic acid metabolic process lipid hydroxylation placenta development | endoplasmic reticulum membrane; extracellular space; intracellular membrane-bounded organelle | 16-hydroxypalmitate dehydrogenase activity alkane 1-monooxygenase activity arachidonic acid monooxygenase activity heme binding iron ion binding long-chain fatty acid omega-hydroxylase activity medium-chain fatty acid omega-hydroxylase activity | Rattus norvegicus | Direct protein sequencing Endoplasmic reticulum Fatty acid metabolism Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase NADP Oxidoreductase Phosphoprotein Reference proteome Transmembrane Transmembrane helix | MSVSALSSTR | MSVSALSSTRFTGSISGFLQVASVLGLLLLLVKAVQFYLQRQWLLKAFQQFPSPPFHWFFGHKQFQGDKELQQIMTCVENFPSAFPRWFWGSKAYLIVYDPDYMKVILGRSDPKANGVYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWEQLAGQDSSIEIFQHISLMTLDTVMKCAFSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDTIYNFSSNGHLFNRACQLAHDHTDGVIKLRKDQLQNAGELEKVKKKRRLDFLDILLLARMENGDSLSDKDLRAEVDTFMFE... | arachidonic acid metabolic process icosanoid biosynthetic process kidney development lauric acid metabolic process linoleic acid metabolic process lipid hydroxylation placenta development endoplasmic reticulum membrane; extracellular space; intracellular membrane-bounded organelle 16-hydroxypalmitate dehydrogenase acti... |
neurogenesis sensory perception of smell signal transduction | axon; cytoplasm; cytosol; neuronal cell body; nucleus | peptide binding | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Olfaction Reference proteome Sensory transduction | MAEDGPQKQQ | MAEDGPQKQQLDMPLVLDQDLTKQMRLRVESLKQRGEKKQDGEKLLRPAESVYRLDFIQQQKLQFDHWNVVLDKPGKVTITGTSQNWTPDLTNLMTRQLLDPAAIFWRKEDSDAMDWNEADALEFGERLSDLAKIRKVMYFLITFGEGVEPANLKASVVFNQL | neurogenesis sensory perception of smell signal transduction axon; cytoplasm; cytosol; neuronal cell body; nucleus peptide binding Rattus norvegicus 3D-structure Acetylation Cytoplasm Direct protein sequencing Olfaction Reference proteome Sensory transduction MAEDGPQKQQ MAEDGPQKQQLDMPLVLDQDLTKQMRLRVESLKQRGEKKQDGEKLLRPA... |
ergosterol biosynthetic process farnesyl diphosphate biosynthetic process geranyl diphosphate biosynthetic process isoprenoid biosynthetic process | cytoplasm; endoplasmic reticulum; vacuole | dimethylallyltranstransferase activity geranyltranstransferase activity isopentenyl-diphosphate delta-isomerase activity metal ion binding | Saccharomyces cerevisiae | Isoprene biosynthesis Lipid biosynthesis Lipid metabolism Magnesium Metal-binding Reference proteome Transferase | MASEKEIRRE | MASEKEIRRERFLNVFPKLVEELNASLLAYGMPKEACDWYAHSLNYNTPGGKLNRGLSVVDTYAILSNKTVEQLGQEEYEKVAILGWCIELLQAYFLVADDMMDKSITRRGQPCWYKVPEVGEIAINDAFMLEAAIYKLLKSHFRNEKYYIDITELFHEVTFQTELGQLMDLITAPEDKVDLSKFSLKKHSFIVTFKTAYYSFYLPVALAMYVAGITDEKDLKQARDVLIPLGEYFQIQDDYLDCFGTPEQIGKIGTDIQDNKCSWVINKALELASAEQRKTLDENYGKKDSVAEAKCKKIFNDLKIEQLYHEYEESIAK... | ergosterol biosynthetic process farnesyl diphosphate biosynthetic process geranyl diphosphate biosynthetic process isoprenoid biosynthetic process cytoplasm; endoplasmic reticulum; vacuole dimethylallyltranstransferase activity geranyltranstransferase activity isopentenyl-diphosphate delta-isomerase activity metal ion ... |
hydrogen sulfide biosynthetic process sulfate assimilation via adenylyl sulfate reduction sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) sulfur amino acid metabolic process | cytoplasm; mitochondrion | ATP binding sulfate adenylyltransferase (ATP) activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm Nucleotide-binding Nucleotidyltransferase Reference proteome Transferase | MPAPHGGILQ | MPAPHGGILQDLIARDALKKNELLSEAQSSDILVWNLTPRQLCDIELILNGGFSPLTGFLNENDYSSVVTDSRLADGTLWTIPITLDVDEAFANQIKPDTRIALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGDPEHPAISYLFNVAGDYYVGGSLEAIQLPQHYDYPGLRKTPAQLRLEFQSRQWDRVVAFQTRNPMHRAHRELTVRAAREANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKRYPNGIAFLSLLPLAMRMSGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGPYDAQELVESYKHE... | hydrogen sulfide biosynthetic process sulfate assimilation via adenylyl sulfate reduction sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) sulfur amino acid metabolic process cytoplasm; mitochondrion ATP binding sulfate adenylyltransferase (ATP) activity Sacchar... |
microtubule-based process | cytoplasm; microtubule | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Xenopus laevis | Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MRECISIHVG | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVADITNACFEPANQMVKCDPRHGKYMACCLLYR... | microtubule-based process cytoplasm; microtubule GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Xenopus laevis Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome MRECISIHVG MRECISIHVGQAGVQIGNACWELYCL... |
G protein-coupled receptor signaling pathway karyogamy involved in conjugation with cellular fusion nuclear migration involved in conjugation with cellular fusion pheromone-dependent signal transduction involved in conjugation with cellular fusion regulation of MAPK export from nucleus | cytosol; endosome; endosome membrane; heterotrimeric G-protein complex; plasma membrane | G protein-coupled receptor binding G-protein beta-subunit binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity metal ion binding | Saccharomyces cerevisiae | 3D-structure Cell membrane Endosome GTP-binding Isopeptide bond Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Palmitate Pheromone response Reference proteome Transducer Ubl conjugation | MGCTVSTQTI | MGCTVSTQTIGDESDPFLQNKRANDVIEQSLQLEKQRDKNEIKLLLLGAGESGKSTVLKQLKLLHQGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQSTGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFARSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIGSSKFKVLDA... | G protein-coupled receptor signaling pathway karyogamy involved in conjugation with cellular fusion nuclear migration involved in conjugation with cellular fusion pheromone-dependent signal transduction involved in conjugation with cellular fusion regulation of MAPK export from nucleus cytosol; endosome; endosome membr... |
cellular glucuronidation cellular response to ethanol cellular response to glucocorticoid stimulus cellular response to growth hormone stimulus cellular response to testosterone stimulus estrogen metabolic process response to lipopolysaccharide | endoplasmic reticulum membrane | glucuronosyltransferase activity | Rattus norvegicus | Endoplasmic reticulum Glycosyltransferase Lipid metabolism Membrane Reference proteome Signal Steroid metabolism Transferase Transmembrane Transmembrane helix | MPGKWISALL | MPGKWISALLLLQISCCFQSGNCGKVLVWPMEFSHWMNIKTILDELVQRGHEVTVLKPSAYYVLDPKKSPDLKFETFPTSVSKDELENYFIKLVDVWTYELQRDTCLSYSPLLQNMIDGFSDYYLSLCKDTVSNKQLMAKLQESKFDVLLSDPVAACGELIAEVLHIPFLYSLRFSPGYKIEKSSGRFILPPSYVPVILSGMGGPMTFIDRVKNMICTLYFDFWFHMFNAKKWDPFYSEILGRPTTLAETMGKAEMWLIRSYWDLEFPHPTLPNVDYIGGLQCRPPKPLPKDMEDFVQSSGEHGVVVFSLGSMVSSMTEE... | cellular glucuronidation cellular response to ethanol cellular response to glucocorticoid stimulus cellular response to growth hormone stimulus cellular response to testosterone stimulus estrogen metabolic process response to lipopolysaccharide endoplasmic reticulum membrane glucuronosyltransferase activity Rattus norv... |
anterograde axonal transport axonal transport of mitochondrion axonogenesis cerebral cortex development hippocampus development intermediate filament bundle assembly intermediate filament organization intermediate filament polymerization or depolymerization locomotion microtubule cytoskeleton organization motor neuron ... | axon; axon cytoplasm; cholinergic synapse; cytoplasm; growth cone; intermediate filament; myelin sheath; neurofilament; neuromuscular junction; neuron projection; postsynaptic intermediate filament cytoskeleton; presynaptic intermediate filament cytoskeleton; Schaffer collateral - CA1 synapse | identical protein binding phospholipase binding protein domain specific binding protein-containing complex binding protein-macromolecule adaptor activity structural constituent of cytoskeleton structural constituent of postsynaptic intermediate filament cytoskeleton | Mus musculus | Acetylation Cell projection Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Glycoprotein Intermediate filament Methylation Phosphoprotein Reference proteome Ubl conjugation | MSSFGYDPYF | MSSFGYDPYFSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEIAFLKKVHEEEIAELQAQIQYAQISVEMDVSSKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEI... | anterograde axonal transport axonal transport of mitochondrion axonogenesis cerebral cortex development hippocampus development intermediate filament bundle assembly intermediate filament organization intermediate filament polymerization or depolymerization locomotion microtubule cytoskeleton organization motor neuron ... |
axo-dendritic transport intermediate filament bundle assembly intermediate filament cytoskeleton organization intermediate filament polymerization or depolymerization microtubule cytoskeleton organization neurofilament bundle assembly neurofilament cytoskeleton organization regulation of axon diameter | axon; cytoplasm; cytoskeleton; intermediate filament; intermediate filament cytoskeleton; myelin sheath; neurofibrillary tangle; neurofilament; neuromuscular junction; neuron projection; perikaryon; postsynaptic density; postsynaptic intermediate filament cytoskeleton; presynaptic intermediate filament cytoskeleton | protein-containing complex binding signaling receptor binding structural constituent of cytoskeleton toxic substance binding | Mus musculus | Acetylation Cell projection Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Glycoprotein Intermediate filament Methylation Phosphoprotein Reference proteome | MSYTLDSLGN | MSYTLDSLGNPSAYRRVTETRSSFSRVSGSPSSGFRSQSWSRGSPSTVSSSYKRSALAPRLAYSSAMLSSAESSLDFSQSSSLLNGGSGGDYKLSRSNEKEQLQGLNDRFAGYIEKVHYLEQQNKEIEAEIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEESSMVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLECHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRR... | axo-dendritic transport intermediate filament bundle assembly intermediate filament cytoskeleton organization intermediate filament polymerization or depolymerization microtubule cytoskeleton organization neurofilament bundle assembly neurofilament cytoskeleton organization regulation of axon diameter axon; cytoplasm; ... |
defense response to protozoan negative regulation of skeletal muscle tissue development positive regulation of angiogenesis positive regulation of endothelial cell proliferation positive regulation of fibroblast proliferation positive regulation of type II interferon production Ras protein signal transduction regulatio... | Golgi apparatus; Golgi membrane; membrane; plasma membrane | G protein activity GDP binding GTP binding GTPase activity protein-containing complex binding | Mus musculus | Acetylation Cell membrane Golgi apparatus GTP-binding Hydrolase Isopeptide bond Lipoprotein Membrane Methylation Nucleotide-binding Palmitate Phosphoprotein Prenylation Proto-oncogene Reference proteome Ubl conjugation | MTEYKLVVVG | MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDLPTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRLKKLNSSDDGTQGCMGSPCVLM | defense response to protozoan negative regulation of skeletal muscle tissue development positive regulation of angiogenesis positive regulation of endothelial cell proliferation positive regulation of fibroblast proliferation positive regulation of type II interferon production Ras protein signal transduction regulatio... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.