Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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epithelial cell differentiation negative regulation of apoptotic process negative regulation of interleukin-8 production negative regulation of NF-kappaB transcription factor activity Notch signaling pathway regulation of transcription by RNA polymerase II signal transduction | cell surface; collagen-containing extracellular matrix; cytoplasm; extracellular exosome; nuclear membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; vesicle membrane; zymogen granule membrane | calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding identical protein binding NF-kappaB binding phospholipase inhibitor activity | Homo sapiens | 3D-structure Acetylation Alternative initiation Alternative splicing Annexin Calcium Calcium/phospholipid-binding Cytoplasmic vesicle Direct protein sequencing Membrane Phosphoprotein Reference proteome Repeat | MATKGGTVKA | MATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD | epithelial cell differentiation negative regulation of apoptotic process negative regulation of interleukin-8 production negative regulation of NF-kappaB transcription factor activity Notch signaling pathway regulation of transcription by RNA polymerase II signal transduction cell surface; collagen-containing extracellular matrix; cytoplasm; extracellular exosome; nuclear membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; vesicle membrane; zymogen granule membrane calcium ion binding calcium-dependent phospholipid binding calcium-dependent protein binding identical protein binding NF-kappaB binding phospholipase inhibitor activity Homo sapiens 3D-structure Acetylation Alternative initiation Alternative splicing Annexin Calcium Calcium/phospholipid-binding Cytoplasmic vesicle Direct protein sequencing Membrane Phosphoprotein Reference proteome Repeat MATKGGTVKA MATKGGTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLIDDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRISQTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKKWGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRNKSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSGDYRKVLLVLCGGDD |
autophagosome assembly bone resorption early endosome to late endosome transport endosome to lysosome transport endosome to plasma membrane protein transport epidermal growth factor catabolic process establishment of vesicle localization intracellular transport lipid catabolic process lipophagy negative regulation of exosomal secretion phagosome acidification phagosome-lysosome fusion positive regulation of exosomal secretion positive regulation of protein catabolic process positive regulation of viral process protein targeting to lysosome protein to membrane docking response to bacterium retrograde transport, endosome to Golgi viral release from host cell | alveolar lamellar body; autophagosome membrane; cytoplasm; cytosol; endosome; endosome membrane; Golgi apparatus; late endosome; late endosome membrane; lipid droplet; lysosomal membrane; lysosome; melanosome membrane; mitochondrial membrane; mitochondrion; phagocytic vesicle; phagocytic vesicle membrane; phagophore assembly site membrane; retromer complex; synaptic vesicle membrane; terminal bouton | G protein activity GDP binding GTP binding GTPase activity retromer complex binding small GTPase binding | Rattus norvegicus | 3D-structure Acetylation Autophagy Cytoplasmic vesicle Endosome GTP-binding Hydrolase Isopeptide bond Lipid degradation Lipid droplet Lipid metabolism Lipoprotein Lysosome Membrane Methylation Mitochondrion Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport Ubl conjugation | MTSRKKVLLK | MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNERAKASAESCSC | autophagosome assembly bone resorption early endosome to late endosome transport endosome to lysosome transport endosome to plasma membrane protein transport epidermal growth factor catabolic process establishment of vesicle localization intracellular transport lipid catabolic process lipophagy negative regulation of exosomal secretion phagosome acidification phagosome-lysosome fusion positive regulation of exosomal secretion positive regulation of protein catabolic process positive regulation of viral process protein targeting to lysosome protein to membrane docking response to bacterium retrograde transport, endosome to Golgi viral release from host cell alveolar lamellar body; autophagosome membrane; cytoplasm; cytosol; endosome; endosome membrane; Golgi apparatus; late endosome; late endosome membrane; lipid droplet; lysosomal membrane; lysosome; melanosome membrane; mitochondrial membrane; mitochondrion; phagocytic vesicle; phagocytic vesicle membrane; phagophore assembly site membrane; retromer complex; synaptic vesicle membrane; terminal bouton G protein activity GDP binding GTP binding GTPase activity retromer complex binding small GTPase binding Rattus norvegicus 3D-structure Acetylation Autophagy Cytoplasmic vesicle Endosome GTP-binding Hydrolase Isopeptide bond Lipid degradation Lipid droplet Lipid metabolism Lipoprotein Lysosome Membrane Methylation Mitochondrion Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport Ubl conjugation MTSRKKVLLK MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNERAKASAESCSC |
immune response intracellular sequestering of iron ion iron ion transport negative regulation of cell population proliferation negative regulation of fibroblast proliferation | autolysosome; cytoplasm; endocytic vesicle lumen; extracellular region; mitochondrion | ferric iron binding ferrous iron binding ferroxidase activity identical protein binding iron ion binding iron ion sequestering activity | Mus musculus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Iron Iron storage Metal-binding Oxidoreductase Reference proteome | MTTASPSQVR | MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETYYLSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGHGDES | immune response intracellular sequestering of iron ion iron ion transport negative regulation of cell population proliferation negative regulation of fibroblast proliferation autolysosome; cytoplasm; endocytic vesicle lumen; extracellular region; mitochondrion ferric iron binding ferrous iron binding ferroxidase activity identical protein binding iron ion binding iron ion sequestering activity Mus musculus 3D-structure Acetylation Cytoplasm Direct protein sequencing Iron Iron storage Metal-binding Oxidoreductase Reference proteome MTTASPSQVR MTTASPSQVRQNYHQDAEAAINRQINLELYASYVYLSMSCYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDRDDWESGLNAMECALHLEKSVNQSLLELHKLATDKNDPHLCDFIETYYLSEQVKSIKELGDHVTNLRKMGAPEAGMAEYLFDKHTLGHGDES |
activin receptor signaling pathway apoptotic signaling pathway cell differentiation cellular response to calcium ion cellular response to cAMP cellular response to cholesterol cellular response to insulin stimulus cellular response to interleukin-1 cellular response to leptin stimulus cellular response to starvation cellular response to Thyroglobulin triiodothyronine cellular response to thyroid hormone stimulus defense response fat cell differentiation negative regulation of follicle-stimulating hormone secretion negative regulation of hepatocyte growth factor production negative regulation of insulin secretion oocyte development ovarian follicle development pituitary gland development positive regulation of apoptotic signaling pathway positive regulation of follicle-stimulating hormone secretion positive regulation of ovulation response to gonadotropin response to insecticide response to wounding seminiferous tubule development spermatogenesis | cell periphery; extracellular region; extracellular space; perinuclear region of cytoplasm | cytokine activity growth factor activity hormone activity host cell surface receptor binding protein homodimerization activity | Homo sapiens | 3D-structure Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Growth factor Hormone Reference proteome Secreted Signal | MDGLPGRALG | MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA | activin receptor signaling pathway apoptotic signaling pathway cell differentiation cellular response to calcium ion cellular response to cAMP cellular response to cholesterol cellular response to insulin stimulus cellular response to interleukin-1 cellular response to leptin stimulus cellular response to starvation cellular response to Thyroglobulin triiodothyronine cellular response to thyroid hormone stimulus defense response fat cell differentiation negative regulation of follicle-stimulating hormone secretion negative regulation of hepatocyte growth factor production negative regulation of insulin secretion oocyte development ovarian follicle development pituitary gland development positive regulation of apoptotic signaling pathway positive regulation of follicle-stimulating hormone secretion positive regulation of ovulation response to gonadotropin response to insecticide response to wounding seminiferous tubule development spermatogenesis cell periphery; extracellular region; extracellular space; perinuclear region of cytoplasm cytokine activity growth factor activity hormone activity host cell surface receptor binding protein homodimerization activity Homo sapiens 3D-structure Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Glycoprotein Growth factor Hormone Reference proteome Secreted Signal MDGLPGRALG MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA |
calcium ion homeostasis chloride ion homeostasis hyperosmotic salinity response magnesium ion homeostasis positive regulation of gene expression positive regulation of oxygen metabolic process positive regulation of P-type sodium:potassium-exchanging transporter activity positive regulation of peptide hormone secretion positive regulation of phagocytosis positive regulation of superoxide anion generation positive regulation of superoxide dismutase activity protein secretion regulation of immunoglobulin production response to dopamine response to external biotic stimulus response to food response to glucose response to growth hormone response to starvation response to temperature stimulus sodium ion homeostasis | cytosol; extracellular space | growth hormone receptor binding hormone activity metal ion binding | Oncorhynchus mykiss | Disulfide bond Hormone Metal-binding Secreted Signal Zinc | MGQVFLLMPV | MGQVFLLMPVLLVSCFLSQGAAIENQRLFNIAVSRVQHLHLLAQKMFNDFDGTLLPDERRQLNKIFLLDFCNSDSIVSPVDKHETQKSSVLKLLHISFRLIESWEYPSQTLIISNSLMVRNANQISEKLSDLKVGINLLITGSQDGVLSLDDNDSQQLPPYGNYYQNLGGDGNVRRNYELLACFKKDMHKVETYLTVAKCRKSLEANCTL | calcium ion homeostasis chloride ion homeostasis hyperosmotic salinity response magnesium ion homeostasis positive regulation of gene expression positive regulation of oxygen metabolic process positive regulation of P-type sodium:potassium-exchanging transporter activity positive regulation of peptide hormone secretion positive regulation of phagocytosis positive regulation of superoxide anion generation positive regulation of superoxide dismutase activity protein secretion regulation of immunoglobulin production response to dopamine response to external biotic stimulus response to food response to glucose response to growth hormone response to starvation response to temperature stimulus sodium ion homeostasis cytosol; extracellular space growth hormone receptor binding hormone activity metal ion binding Oncorhynchus mykiss Disulfide bond Hormone Metal-binding Secreted Signal Zinc MGQVFLLMPV MGQVFLLMPVLLVSCFLSQGAAIENQRLFNIAVSRVQHLHLLAQKMFNDFDGTLLPDERRQLNKIFLLDFCNSDSIVSPVDKHETQKSSVLKLLHISFRLIESWEYPSQTLIISNSLMVRNANQISEKLSDLKVGINLLITGSQDGVLSLDDNDSQQLPPYGNYYQNLGGDGNVRRNYELLACFKKDMHKVETYLTVAKCRKSLEANCTL |
cardiac muscle contraction regulation of striated muscle contraction regulation of the force of heart contraction ventricular cardiac muscle tissue morphogenesis | A band; I band; myosin complex; myosin II complex | actin monomer binding calcium ion binding cytoskeletal motor activity | Mus musculus | Methylation Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Repeat | MAPKKPEPKK | MAPKKPEPKKDDAKAAAPKAAPAPAAAPAAAPAAAPEPERPKEAEFDASKIKIEFTPEQIEEFKEAFLLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMAS | cardiac muscle contraction regulation of striated muscle contraction regulation of the force of heart contraction ventricular cardiac muscle tissue morphogenesis A band; I band; myosin complex; myosin II complex actin monomer binding calcium ion binding cytoskeletal motor activity Mus musculus Methylation Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Repeat MAPKKPEPKK MAPKKPEPKKDDAKAAAPKAAPAPAAAPAAAPAAAPEPERPKEAEFDASKIKIEFTPEQIEEFKEAFLLFDRTPKGEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQEELNSKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMAS |
adult locomotory behavior axonogenesis chemical synaptic transmission cyclic nucleotide catabolic process forebrain development oligodendrocyte differentiation regulation of mitochondrial membrane permeability response to lipopolysaccharide response to toxic substance substantia nigra development | cytoplasm; extracellular exosome; extracellular space; melanosome; membrane; microtubule; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath abaxonal region; myelin sheath adaxonal region; perinuclear region of cytoplasm; pseudopodium; synapse | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding RNA binding | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Hydrolase Leukodystrophy Lipoprotein Membrane Methylation Neurodegeneration Phosphoprotein Prenylation Reference proteome RNA-binding | MNRGFSRKSH | MNRGFSRKSHTFLPKIFFRKMSSSGAKDKPELQFPFLQDEDTVATLLECKTLFILRGLPGSGKSTLARVIVDKYRDGTKMVSADAYKITPGARGAFSEEYKRLDEDLAAYCRRRDIRILVLDDTNHERERLEQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRQFVPGDEPREKMDLVTYFGKRPPGVLHCTTKFCDYGKAPGAEEYAQQDVLKKSYSKAFTLTISALFVTPKTTGARVELSEQQLQLWPSDVDKLSPTDNLPRGSRAHITLGCAADVEAVQTGLDLLEILRQEKGGSRGEEVGELSRGKLYSLGNGRWMLTLAKNMEVRAIFTGYYGKGKPVPTQGSRKGGALQSCTII | adult locomotory behavior axonogenesis chemical synaptic transmission cyclic nucleotide catabolic process forebrain development oligodendrocyte differentiation regulation of mitochondrial membrane permeability response to lipopolysaccharide response to toxic substance substantia nigra development cytoplasm; extracellular exosome; extracellular space; melanosome; membrane; microtubule; microvillus; mitochondrial inner membrane; mitochondrial outer membrane; myelin sheath abaxonal region; myelin sheath adaxonal region; perinuclear region of cytoplasm; pseudopodium; synapse 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity cyclic nucleotide binding RNA binding Homo sapiens 3D-structure Alternative splicing Direct protein sequencing Hydrolase Leukodystrophy Lipoprotein Membrane Methylation Neurodegeneration Phosphoprotein Prenylation Reference proteome RNA-binding MNRGFSRKSH MNRGFSRKSHTFLPKIFFRKMSSSGAKDKPELQFPFLQDEDTVATLLECKTLFILRGLPGSGKSTLARVIVDKYRDGTKMVSADAYKITPGARGAFSEEYKRLDEDLAAYCRRRDIRILVLDDTNHERERLEQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSADDLKKLKPGLEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRQFVPGDEPREKMDLVTYFGKRPPGVLHCTTKFCDYGKAPGAEEYAQQDVLKKSYSKAFTLTISALFVTPKTTGARVELSEQQLQLWPSDVDKLSPTDNLPRGSRAHITLGCAADVEAVQTGLDLLEILRQEKGGSRGEEVGELSRGKLYSLGNGRWMLTLAKNMEVRAIFTGYYGKGKPVPTQGSRKGGALQSCTII |
cytolysis in another organism | extracellular region; host cell plasma membrane; membrane | carbohydrate binding identical protein binding toxin activity | Vibrio cholerae serotype O1 | 3D-structure Cytolysis Direct protein sequencing Disulfide bond Hemolysis Host cell membrane Host membrane Lectin Membrane Reference proteome Secreted Signal Toxin Transmembrane Transmembrane beta strand Virulence | MPKLNRCAIA | MPKLNRCAIAIFTILSAISSPTLLANINEPSGEAADIISQVADSHAIKYYNAADWQAEDNALPSLAELRDLVINQQKRVLVDFSQISDAEGQAEMQAQFRKAYGVGFANQFIVITEHKGELLFTPFDQAEEVDPQLLEAPRTARLLARSGFASPAPANSETNTLPHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNINEKFERKEVSGFELGVTGGVEVSGDGPKAKLEARASYTQSRWLTYNTQDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQSYHGFEDTPRRRITKSASFTVDWDHPVFTGGRPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGLYASSNDAVSLRTITAYTDVFNAQESSPILGYTQGKMNQQRVGQDHRLYVRAGAAIDALGSASDLLVGGNGGSLSSVDLSGVKSITATSGDFQYGGQQLVALTFTYQDGRQQTVGSKAYVTNAHEDRFDLPAAAKITQLKIWSDDWLVKGVQFDLN | cytolysis in another organism extracellular region; host cell plasma membrane; membrane carbohydrate binding identical protein binding toxin activity Vibrio cholerae serotype O1 3D-structure Cytolysis Direct protein sequencing Disulfide bond Hemolysis Host cell membrane Host membrane Lectin Membrane Reference proteome Secreted Signal Toxin Transmembrane Transmembrane beta strand Virulence MPKLNRCAIA MPKLNRCAIAIFTILSAISSPTLLANINEPSGEAADIISQVADSHAIKYYNAADWQAEDNALPSLAELRDLVINQQKRVLVDFSQISDAEGQAEMQAQFRKAYGVGFANQFIVITEHKGELLFTPFDQAEEVDPQLLEAPRTARLLARSGFASPAPANSETNTLPHVAFYISVNRAISDEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQDYRFVFNASNNKAQILKTFPVDNINEKFERKEVSGFELGVTGGVEVSGDGPKAKLEARASYTQSRWLTYNTQDYRIERNAKNAQAVSFTWNRQQYATAESLLNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFIIDSSVNIRPIYNGAYKHYYVVGAHQSYHGFEDTPRRRITKSASFTVDWDHPVFTGGRPVNLQLASFNNRCIQVDAQGRLAANTCDSQQSAQSFIYDQLGRYVSASNTKLCLDGEALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHDKQTGELGLYASSNDAVSLRTITAYTDVFNAQESSPILGYTQGKMNQQRVGQDHRLYVRAGAAIDALGSASDLLVGGNGGSLSSVDLSGVKSITATSGDFQYGGQQLVALTFTYQDGRQQTVGSKAYVTNAHEDRFDLPAAAKITQLKIWSDDWLVKGVQFDLN |
adaptive immune response immune response T cell activation transmembrane receptor protein tyrosine kinase signaling pathway | membrane; plasma membrane | signaling receptor activity | Homo sapiens | Adaptive immunity Disulfide bond Glycoprotein Immunity Immunoglobulin domain Lipoprotein Membrane Palmitate Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MAGPPRLLLL | MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALPAALAVISFLLGLGLGVACVLARTQIKKLCSWRDKNSAACVVYEDMSHSRCNTLSSPNQYQ | adaptive immune response immune response T cell activation transmembrane receptor protein tyrosine kinase signaling pathway membrane; plasma membrane signaling receptor activity Homo sapiens Adaptive immunity Disulfide bond Glycoprotein Immunity Immunoglobulin domain Lipoprotein Membrane Palmitate Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix MAGPPRLLLL MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALPAALAVISFLLGLGLGVACVLARTQIKKLCSWRDKNSAACVVYEDMSHSRCNTLSSPNQYQ |
intracellular potassium ion homeostasis intracellular sodium ion homeostasis potassium ion import across plasma membrane proton transmembrane transport sodium ion export across plasma membrane | basolateral part of cell; membrane; plasma membrane; sarcolemma; sodium:potassium-exchanging ATPase complex | ATP binding ATP hydrolysis activity metal ion binding P-type sodium:potassium-exchanging transporter activity | Gallus gallus | ATP-binding Cell membrane Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Sodium Sodium transport Sodium/potassium transport Translocase Transmembrane Transmembrane helix Transport | MGKGAGRDKY | MGKGAGRDKYEPTATSEHGTKKKKAKERDMDELKKEISMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNTLTPPPTTPEWVKFCRQLFGGFSLLLWIGSLLCFLAYGITSVMEGEPNSDNLYLGVVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVVRNGEKMSINAEGVVVGDLVEVKGGDRIPADLRIISAHGCKVDNSSLTGESEPQTRSPDFSNENPLETRNIAFFSTNCVEGTAVGIVISTGDRTVMGRIASLASGLEGGKTPIAMEIEHFIHLITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVGTLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGASFDKSSATWLALSRIAGLCNRAVFQANQENVPILKRAVAGDASESALLKCIELCCGSVKEMRERYPKVVEIPFNSTNKYQLSIHKNANAGESRHLLVMKGAPERILDRCDSILIHGKVQPLDEEIKDAFQNAYLELGGLGERVLGFCHLALPDDQFPEGFQFDTDEVNFPVEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISDGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILLHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTCTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPSGLVGIRLQWDDRWINDVEDSYGQQWTFEQRKIVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPTWWFCAFPYSLLIFLYDEIRKLIIRRNPGGWVERETYY | intracellular potassium ion homeostasis intracellular sodium ion homeostasis potassium ion import across plasma membrane proton transmembrane transport sodium ion export across plasma membrane basolateral part of cell; membrane; plasma membrane; sarcolemma; sodium:potassium-exchanging ATPase complex ATP binding ATP hydrolysis activity metal ion binding P-type sodium:potassium-exchanging transporter activity Gallus gallus ATP-binding Cell membrane Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Potassium Potassium transport Reference proteome Sodium Sodium transport Sodium/potassium transport Translocase Transmembrane Transmembrane helix Transport MGKGAGRDKY MGKGAGRDKYEPTATSEHGTKKKKAKERDMDELKKEISMDDHKLSLDELHRKYGTDLSRGLTTARAAEILARDGPNTLTPPPTTPEWVKFCRQLFGGFSLLLWIGSLLCFLAYGITSVMEGEPNSDNLYLGVVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVVRNGEKMSINAEGVVVGDLVEVKGGDRIPADLRIISAHGCKVDNSSLTGESEPQTRSPDFSNENPLETRNIAFFSTNCVEGTAVGIVISTGDRTVMGRIASLASGLEGGKTPIAMEIEHFIHLITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVGTLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGASFDKSSATWLALSRIAGLCNRAVFQANQENVPILKRAVAGDASESALLKCIELCCGSVKEMRERYPKVVEIPFNSTNKYQLSIHKNANAGESRHLLVMKGAPERILDRCDSILIHGKVQPLDEEIKDAFQNAYLELGGLGERVLGFCHLALPDDQFPEGFQFDTDEVNFPVEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISDGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILLHHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTCTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVIMAENGFLPSGLVGIRLQWDDRWINDVEDSYGQQWTFEQRKIVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPTWWFCAFPYSLLIFLYDEIRKLIIRRNPGGWVERETYY |
DNA repair regulation of DNA-templated transcription | nucleosome; nucleus | DNA binding protein heterodimerization activity structural constituent of chromatin | Caenorhabditis elegans | 3D-structure Acetylation Chromosome Direct protein sequencing DNA-binding Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSGRGKGGKA | MSGRGKGGKAKTGGKAKSRSSRAGLQFPVGRLHRILRKGNYAQRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLPKKTGGDKE | DNA repair regulation of DNA-templated transcription nucleosome; nucleus DNA binding protein heterodimerization activity structural constituent of chromatin Caenorhabditis elegans3D-structure Acetylation Chromosome Direct protein sequencing DNA-binding Isopeptide bond Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome Ubl conjugation MSGRGKGGKA MSGRGKGGKAKTGGKAKSRSSRAGLQFPVGRLHRILRKGNYAQRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLPKKTGGDKE |
antimicrobial humoral immune response mediated by antimicrobial peptide chromatin organization killing of cells of another organism negative regulation of transcription by RNA polymerase II regulation of development, heterochronic regulation of transcription by RNA polymerase II | chromatin; cytoplasm; extracellular space; female germ cell nucleus; nucleus | chromatin binding nucleosomal DNA binding | Mus musculus | Acetylation ADP-ribosylation Cytoplasm Direct protein sequencing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation | MPKRKAEGDA | MPKRKAEGDAKGDKTKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKAEGAGDAK | antimicrobial humoral immune response mediated by antimicrobial peptide chromatin organization killing of cells of another organism negative regulation of transcription by RNA polymerase II regulation of development, heterochronic regulation of transcription by RNA polymerase II chromatin; cytoplasm; extracellular space; female germ cell nucleus; nucleus chromatin binding nucleosomal DNA binding Mus musculus Acetylation ADP-ribosylation Cytoplasm Direct protein sequencing DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Ubl conjugation MPKRKAEGDA MPKRKAEGDAKGDKTKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKAEGAGDAK |
heart development phosphocreatine biosynthetic process phosphorylation skeletal muscle tissue development | mitochondrial inner membrane; mitochondrion | ATP binding cardiolipin binding creatine kinase activity | Rattus norvegicus | ATP-binding Direct protein sequencing Kinase Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transferase Transit peptide | MASAFSKLLT | MASAFSKLLTGRNASLLFTTLGTSALTTGYLLNRQKVSADAREQHKLFPPSADYPDLRKHNNCMAECLTPTIYAKLRNKMTPSGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRLMKHPADLDASKITHGQFDERYVLSSRVRTGRSIRGLSLPPACSRAERREVENVAITALGGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGRK | heart development phosphocreatine biosynthetic process phosphorylation skeletal muscle tissue development mitochondrial inner membrane; mitochondrion ATP binding cardiolipin binding creatine kinase activity Rattus norvegicus ATP-binding Direct protein sequencing Kinase Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transferase Transit peptide MASAFSKLLT MASAFSKLLTGRNASLLFTTLGTSALTTGYLLNRQKVSADAREQHKLFPPSADYPDLRKHNNCMAECLTPTIYAKLRNKMTPSGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRLMKHPADLDASKITHGQFDERYVLSSRVRTGRSIRGLSLPPACSRAERREVENVAITALGGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGRK |
ammonia assimilation cycle angiogenesis cell population proliferation cellular response to starvation glutamate metabolic process glutamine biosynthetic process positive regulation of epithelial cell proliferation positive regulation of insulin secretion positive regulation of synaptic transmission, glutamatergic protein palmitoylation regulation of endothelial cell migration regulation of protein localization to nucleolus regulation of sprouting angiogenesis response to glucose ribosome biogenesis | axon terminus; cell body; cell projection; cytoplasm; cytosol; endoplasmic reticulum; glial cell projection; mitochondrion; myelin sheath; perikaryon; plasma membrane; protein-containing complex | ATP binding dynein light chain binding glutamate binding glutamine synthetase activity identical protein binding magnesium ion binding manganese ion binding nickel cation binding protein-cysteine S-palmitoyltransferase activity | Rattus norvegicus | Acetylation Angiogenesis ATP-binding Cell membrane Cytoplasm Direct protein sequencing Endoplasmic reticulum Ligase Lipoprotein Magnesium Manganese Membrane Metal-binding Microsome Mitochondrion Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transferase Ubl conjugation | MATSASSHLN | MATSASSHLNKGIKQMYMNLPQGEKIQLMYIWVDGTGEGLRCKTRTLDCDPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRRDPNKLVFCEVFKYNRKPAETNLRHSCKRIMDMVSSQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLRCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRIVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCLLNETGDEPFQYKN | ammonia assimilation cycle angiogenesis cell population proliferation cellular response to starvation glutamate metabolic process glutamine biosynthetic process positive regulation of epithelial cell proliferation positive regulation of insulin secretion positive regulation of synaptic transmission, glutamatergic protein palmitoylation regulation of endothelial cell migration regulation of protein localization to nucleolus regulation of sprouting angiogenesis response to glucose ribosome biogenesis axon terminus; cell body; cell projection; cytoplasm; cytosol; endoplasmic reticulum; glial cell projection; mitochondrion; myelin sheath; perikaryon; plasma membrane; protein-containing complex ATP binding dynein light chain binding glutamate binding glutamine synthetase activity identical protein binding magnesium ion binding manganese ion binding nickel cation binding protein-cysteine S-palmitoyltransferase activity Rattus norvegicus Acetylation Angiogenesis ATP-binding Cell membrane Cytoplasm Direct protein sequencing Endoplasmic reticulum Ligase Lipoprotein Magnesium Manganese Membrane Metal-binding Microsome Mitochondrion Nucleotide-binding Palmitate Phosphoprotein Reference proteome Transferase Ubl conjugation MATSASSHLN MATSASSHLNKGIKQMYMNLPQGEKIQLMYIWVDGTGEGLRCKTRTLDCDPKCVEELPEWNFDGSSTFQSEGSNSDMYLHPVAMFRDPFRRDPNKLVFCEVFKYNRKPAETNLRHSCKRIMDMVSSQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKITGTNAEVMPAQWEFQIGPCEGIRMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLRCIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRIVGQEKKGYFEDRRPSANCDPYAVTEAIVRTCLLNETGDEPFQYKN |
cholesterol biosynthetic process coenzyme A metabolic process isoprenoid biosynthetic process | endoplasmic reticulum; endoplasmic reticulum membrane; peroxisomal membrane | hydroxymethylglutaryl-CoA reductase (NADPH) activity NADP binding | Mesocricetus auratus | Cholesterol biosynthesis Cholesterol metabolism Endoplasmic reticulum Glycoprotein Isopeptide bond Lipid biosynthesis Lipid metabolism Membrane NADP Oxidoreductase Peroxisome Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transmembrane Transmembrane helix Ubl conjugation | MLSRLFRMHG | MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTTEHSKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVVTLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVATPKKAPDNCCRREPVLSRRNEKLSSVEEEPGVNQDRKVEVIKPLVAETESTSRATFVLGASGGCSPVALGTQEPEIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLPEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKDAFDSTSRFARLQKLHVTMAGRNLYIRFQSKTGDAMGMNMISKGTEKALVKLQEFFPEMQILAVSGNYCTDKKPAAVNWIEGRGKTVVCEAVIPARVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA | cholesterol biosynthetic process coenzyme A metabolic process isoprenoid biosynthetic process endoplasmic reticulum; endoplasmic reticulum membrane; peroxisomal membrane hydroxymethylglutaryl-CoA reductase (NADPH) activity NADP binding Mesocricetus auratus Cholesterol biosynthesis Cholesterol metabolism Endoplasmic reticulum Glycoprotein Isopeptide bond Lipid biosynthesis Lipid metabolism Membrane NADP Oxidoreductase Peroxisome Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transmembrane Transmembrane helix Ubl conjugation MLSRLFRMHG MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTTEHSKVSLGLDEDVSKRIEPSVSLWQFYLSKMISMDIEQVVTLSLAFLLAVKYIFFEQAETESTLSLKNPITSPVATPKKAPDNCCRREPVLSRRNEKLSSVEEEPGVNQDRKVEVIKPLVAETESTSRATFVLGASGGCSPVALGTQEPEIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSTKLPEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETPEGFAVIKDAFDSTSRFARLQKLHVTMAGRNLYIRFQSKTGDAMGMNMISKGTEKALVKLQEFFPEMQILAVSGNYCTDKKPAAVNWIEGRGKTVVCEAVIPARVVREVLKTTTEAMIDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA |
cytolysis in another organism | extracellular region | identical protein binding toxin activity | Staphylococcus aureus | 3D-structure Cytolysis Direct protein sequencing Hemolysis Secreted Signal Toxin Virulence | MKTRIVSSVT | MKTRIVSSVTTTLLLGSILMNPVAGAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN | cytolysis in another organism extracellular region identical protein binding toxin activity Staphylococcus aureus3D-structure Cytolysis Direct protein sequencing Hemolysis Secreted Signal Toxin Virulence MKTRIVSSVT MKTRIVSSVTTTLLLGSILMNPVAGAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN |
apoptotic process proteolysis | fungal-type vacuole; membrane; trans-Golgi network | serine-type carboxypeptidase activity | Saccharomyces cerevisiae | 3D-structure Apoptosis Carboxypeptidase Glycoprotein Golgi apparatus Hydrolase Membrane Phosphoprotein Protease Reference proteome Signal Transmembrane Transmembrane helix | MFYNRWLGTW | MFYNRWLGTWLAMSALIRISVSLPSSEEYKVAYELLPGLSEVPDPSNIPQMHAGHIPLRSEDADEQDSSDLEYFFWKFTNNDSNGNVDRPLIIWLNGGPGCSSMDGALVESGPFRVNSDGKLYLNEGSWISKGDLLFIDQPTGTGFSVEQNKDEGKIDKNKFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAILNHNKFSKIDGDTYDLKALLIGNGWIDPNTQSLSYLPFAMEKKLIDESNPNFKHLTNAHENCQNLINSASTDEAAHFSYQECENILNLLLSYTRESSQKGTADCLNMYNFNLKDSYPSCGMNWPKDISFVSKFFSTPGVIDSLHLDSDKIDHWKECTNSVGTKLSNPISKPSIHLLPGLLESGIEIVLFNGDKDLICNNKGVLDTIDNLKWGGIKGFSDDAVSFDWIHKSKSTDDSEEFSGYVKYDRNLTFVSVYNASHMVPFDKSLVSRGIVDIYSNDVMIIDNNGKNVMITTDDDSDQDATTESGDKPKENLEEEEQEAQNEEGKEKEGNKDKDGDDDNDNDDDDEDDHNSEGDDDDDDDDDEDDNNEKQSNQGLEDSRHKSSEYEQEEEEVEEFAEEISMYKHKAVVVTIVTFLIVVLGVYAYDRRVRRKARHTILVDPNNRQHDSPNKTVSWADDLESGLGAEDDLEQDEQLEGGAPISSTSNKAGSKLKTKKKKKYTSLPNTEIDESFEMTDF | apoptotic process proteolysis fungal-type vacuole; membrane; trans-Golgi network serine-type carboxypeptidase activity Saccharomyces cerevisiae 3D-structure Apoptosis Carboxypeptidase Glycoprotein Golgi apparatus Hydrolase Membrane Phosphoprotein Protease Reference proteome Signal Transmembrane Transmembrane helix MFYNRWLGTW MFYNRWLGTWLAMSALIRISVSLPSSEEYKVAYELLPGLSEVPDPSNIPQMHAGHIPLRSEDADEQDSSDLEYFFWKFTNNDSNGNVDRPLIIWLNGGPGCSSMDGALVESGPFRVNSDGKLYLNEGSWISKGDLLFIDQPTGTGFSVEQNKDEGKIDKNKFDEDLEDVTKHFMDFLENYFKIFPEDLTRKIILSGESYAGQYIPFFANAILNHNKFSKIDGDTYDLKALLIGNGWIDPNTQSLSYLPFAMEKKLIDESNPNFKHLTNAHENCQNLINSASTDEAAHFSYQECENILNLLLSYTRESSQKGTADCLNMYNFNLKDSYPSCGMNWPKDISFVSKFFSTPGVIDSLHLDSDKIDHWKECTNSVGTKLSNPISKPSIHLLPGLLESGIEIVLFNGDKDLICNNKGVLDTIDNLKWGGIKGFSDDAVSFDWIHKSKSTDDSEEFSGYVKYDRNLTFVSVYNASHMVPFDKSLVSRGIVDIYSNDVMIIDNNGKNVMITTDDDSDQDATTESGDKPKENLEEEEQEAQNEEGKEKEGNKDKDGDDDNDNDDDDEDDHNSEGDDDDDDDDDEDDNNEKQSNQGLEDSRHKSSEYEQEEEEVEEFAEEISMYKHKAVVVTIVTFLIVVLGVYAYDRRVRRKARHTILVDPNNRQHDSPNKTVSWADDLESGLGAEDDLEQDEQLEGGAPISSTSNKAGSKLKTKKKKKYTSLPNTEIDESFEMTDF |
histone succinylation | acrosomal vesicle; mitochondrial matrix; mitochondrion; motile cilium; nucleus; oxoglutarate dehydrogenase complex | dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding | Sus scrofa | Acetylation Cell projection Cilium Cytoplasmic vesicle Direct protein sequencing Disulfide bond FAD Flagellum Flavoprotein Mitochondrion NAD Nucleus Oxidoreductase Phosphoprotein Redox-active center Reference proteome Transit peptide | MQSWSRVYCT | MQSWSRVYCTLAKRGHFNRIAHGLQGVSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLEKMMEQKSNAVKALTGGIAHLFKQNKVVRVNGYGKITGKNQVTATKADGSTEVINTKNILIATGSEVTPFPGITIDEDTVVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVELLGHVGGIGIDMEVSKNFQRILQKQGFKFKLNTKVIGATKKSDGNIDVSIEAASGGKAEVITCDVLLVCIGRRPFTQNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHIIGPGAGEMINEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKAINF | histone succinylation acrosomal vesicle; mitochondrial matrix; mitochondrion; motile cilium; nucleus; oxoglutarate dehydrogenase complex dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding Sus scrofa Acetylation Cell projection Cilium Cytoplasmic vesicle Direct protein sequencing Disulfide bond FAD Flagellum Flavoprotein Mitochondrion NAD Nucleus Oxidoreductase Phosphoprotein Redox-active center Reference proteome Transit peptide MQSWSRVYCT MQSWSRVYCTLAKRGHFNRIAHGLQGVSAVPLRTYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLEKMMEQKSNAVKALTGGIAHLFKQNKVVRVNGYGKITGKNQVTATKADGSTEVINTKNILIATGSEVTPFPGITIDEDTVVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVELLGHVGGIGIDMEVSKNFQRILQKQGFKFKLNTKVIGATKKSDGNIDVSIEAASGGKAEVITCDVLLVCIGRRPFTQNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHIIGPGAGEMINEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKAINF |
2-oxoglutarate metabolic process acetyl-CoA biosynthetic process from pyruvate glycine catabolic process hydrogen peroxide metabolic process isoleucine catabolic process L-serine biosynthetic process leucine catabolic process pyruvate metabolic process valine catabolic process | glycine cleavage complex; mitochondrial alpha-ketoglutarate dehydrogenase complex; mitochondrial nucleoid; mitochondrial oxoglutarate dehydrogenase complex; mitochondrial pyruvate dehydrogenase complex; mitochondrion; oxoglutarate dehydrogenase complex | dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding glycine dehydrogenase (decarboxylating) activity oxoglutarate dehydrogenase (succinyl-transferring) activity pyruvate dehydrogenase activity | Saccharomyces cerevisiae | 3D-structure Disulfide bond FAD Flavoprotein Mitochondrion NAD Oxidoreductase Redox-active center Reference proteome Transit peptide | MLRIRSLLNN | MLRIRSLLNNKRAFSSTVRTLTINKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEMLKTGHGHVNYNNIPSVMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAAYDKAIHC | 2-oxoglutarate metabolic process acetyl-CoA biosynthetic process from pyruvate glycine catabolic process hydrogen peroxide metabolic process isoleucine catabolic process L-serine biosynthetic process leucine catabolic process pyruvate metabolic process valine catabolic process glycine cleavage complex; mitochondrial alpha-ketoglutarate dehydrogenase complex; mitochondrial nucleoid; mitochondrial oxoglutarate dehydrogenase complex; mitochondrial pyruvate dehydrogenase complex; mitochondrion; oxoglutarate dehydrogenase complex dihydrolipoyl dehydrogenase activity flavin adenine dinucleotide binding glycine dehydrogenase (decarboxylating) activity oxoglutarate dehydrogenase (succinyl-transferring) activity pyruvate dehydrogenase activity Saccharomyces cerevisiae 3D-structure Disulfide bond FAD Flavoprotein Mitochondrion NAD Oxidoreductase Redox-active center Reference proteome Transit peptide MLRIRSLLNN MLRIRSLLNNKRAFSSTVRTLTINKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEMLKTGHGHVNYNNIPSVMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAAYDKAIHC |
proton export across plasma membrane proton transmembrane transport regulation of intracellular pH | cytoplasm; Golgi apparatus; membrane; plasma membrane | ATP binding ATP hydrolysis activity metal ion binding P-type proton-exporting transporter activity proton binding | Schizosaccharomyces pombe | ATP-binding Cell membrane Hydrogen ion transport Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Translocase Transmembrane Transmembrane helix Transport | MADNAGEYHD | MADNAGEYHDAEKHAPEQQAPPPQQPAHAAAPAQDDEPDDDIDALIEELFSEDVQEEQEDNDDAPAAGEAKAVPEELLQTDMNTGLTMSEVEERRKKYGLNQMKEELENPFLKFIMFFVGPIQFVMEMAAALAAGLRDWVDFGVICALLMLNAVVGFVQEYQAGSIVDELKKSLALKAVVIREGQVHELEANEVVPGDILKLDEGTIICADGRVVTPDVHLQVDQSAITGESLAVDKHYGDPTFASSGVKRGEGLMVVTATGDSTFVGRAASLVNAAAGGTGHFTEVLNGIGTILLVLVLLTLFCIYTAAFYRSVRLARLLEYTLAITIIGVPVGLPAVVTTTMAVGAAYLAEKQAIVQKLSAIESLAGVEVLCSDKTGTLTKNKLSLGEPFTVSGVSGDDLVLTACLAASRKRKGLDAIDKAFLKALKNYPGPRSMLTKYKVIEFQPFDPVSKKVTAYVQAPDGTRITCVKGAPLWVLKTVEEDHPIPEDVLSAYKDKVGDLASRGYRSLGVARKIEGQHWEIMGIMPCSDPPRHDTARTISEAKRLGLRVKMLTGDAVDIAKETARQLGMGTNIYNAERLGLTGGGNMPGSEVYDFVEAADGFGEVFPQHKYAVVDILQQRGYLVAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIALSLHLEIFLGLWLIIRNQLLNLELVVFIAIFADVATLAIAYDNAPYSMKPVKWNLPRLWGLSTVIGIVLAIGTWITNTTMIAQGQNRGIVQNFGVQDEVLFLEISLTENWLIFVTRCNGPFWSSIPSWQLSGAVLAVDILATMFCIFGWFKGGHQTSIVAVLRIWMYSFGIFCIMAGTYYILSESAGFDRMMNGKPKESRNQRSIEDLVVALQRTSTRHEKGDA | proton export across plasma membrane proton transmembrane transport regulation of intracellular pH cytoplasm; Golgi apparatus; membrane; plasma membrane ATP binding ATP hydrolysis activity metal ion binding P-type proton-exporting transporter activity proton binding Schizosaccharomyces pombe ATP-binding Cell membrane Hydrogen ion transport Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Translocase Transmembrane Transmembrane helix Transport MADNAGEYHD MADNAGEYHDAEKHAPEQQAPPPQQPAHAAAPAQDDEPDDDIDALIEELFSEDVQEEQEDNDDAPAAGEAKAVPEELLQTDMNTGLTMSEVEERRKKYGLNQMKEELENPFLKFIMFFVGPIQFVMEMAAALAAGLRDWVDFGVICALLMLNAVVGFVQEYQAGSIVDELKKSLALKAVVIREGQVHELEANEVVPGDILKLDEGTIICADGRVVTPDVHLQVDQSAITGESLAVDKHYGDPTFASSGVKRGEGLMVVTATGDSTFVGRAASLVNAAAGGTGHFTEVLNGIGTILLVLVLLTLFCIYTAAFYRSVRLARLLEYTLAITIIGVPVGLPAVVTTTMAVGAAYLAEKQAIVQKLSAIESLAGVEVLCSDKTGTLTKNKLSLGEPFTVSGVSGDDLVLTACLAASRKRKGLDAIDKAFLKALKNYPGPRSMLTKYKVIEFQPFDPVSKKVTAYVQAPDGTRITCVKGAPLWVLKTVEEDHPIPEDVLSAYKDKVGDLASRGYRSLGVARKIEGQHWEIMGIMPCSDPPRHDTARTISEAKRLGLRVKMLTGDAVDIAKETARQLGMGTNIYNAERLGLTGGGNMPGSEVYDFVEAADGFGEVFPQHKYAVVDILQQRGYLVAMTGDGVNDAPSLKKADTGIAVEGATDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYSYVVYRIALSLHLEIFLGLWLIIRNQLLNLELVVFIAIFADVATLAIAYDNAPYSMKPVKWNLPRLWGLSTVIGIVLAIGTWITNTTMIAQGQNRGIVQNFGVQDEVLFLEISLTENWLIFVTRCNGPFWSSIPSWQLSGAVLAVDILATMFCIFGWFKGGHQTSIVAVLRIWMYSFGIFCIMAGTYYILSESAGFDRMMNGKPKESRNQRSIEDLVVALQRTSTRHEKGDA |
anterior/posterior pattern specification embryonic organ development embryonic skeletal system morphogenesis myeloid cell differentiation positive regulation of branching involved in ureteric bud morphogenesis positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II | chromatin; cytosol; nuclear body; nucleoplasm; nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MSSLYYANTL | MSSLYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE | anterior/posterior pattern specification embryonic organ development embryonic skeletal system morphogenesis myeloid cell differentiation positive regulation of branching involved in ureteric bud morphogenesis positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II chromatin; cytosol; nuclear body; nucleoplasm; nucleus DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Homo sapiens Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation MSSLYYANTL MSSLYYANTLFSKYPASSSVFATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESNFRIYPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEEEEE |
anterior/posterior pattern specification definitive hemopoiesis DNA-templated transcription embryonic forelimb morphogenesis embryonic skeletal system development embryonic skeletal system morphogenesis endothelial cell activation male gonad development mammary gland development negative regulation of myeloid cell differentiation positive regulation of transcription by RNA polymerase II prostate gland development proximal/distal pattern formation regulation of gene expression regulation of transcription by RNA polymerase II response to testosterone single fertilization spermatogenesis uterus development | cytoplasm; nucleoplasm; nucleus; transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity enzyme binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | 3D-structure Alternative splicing Cytoplasm Developmental protein DNA-binding Homeobox Methylation Nucleus Reference proteome Transcription Transcription regulation | MATTGALGNY | MATTGALGNYYVDSFLLGADAADELGAGRYAPGTLGQPPRQAAALAEHPDFSPCSFQSKAAVFGASWNPVHAAGANAVPAAVYHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE | anterior/posterior pattern specification definitive hemopoiesis DNA-templated transcription embryonic forelimb morphogenesis embryonic skeletal system development embryonic skeletal system morphogenesis endothelial cell activation male gonad development mammary gland development negative regulation of myeloid cell differentiation positive regulation of transcription by RNA polymerase II prostate gland development proximal/distal pattern formation regulation of gene expression regulation of transcription by RNA polymerase II response to testosterone single fertilization spermatogenesis uterus development cytoplasm; nucleoplasm; nucleus; transcription regulator complex DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity enzyme binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus 3D-structure Alternative splicing Cytoplasm Developmental protein DNA-binding Homeobox Methylation Nucleus Reference proteome Transcription Transcription regulation MATTGALGNY MATTGALGNYYVDSFLLGADAADELGAGRYAPGTLGQPPRQAAALAEHPDFSPCSFQSKAAVFGASWNPVHAAGANAVPAAVYHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE |
adult locomotory behavior anterior/posterior pattern specification dorsal spinal cord development embryonic skeletal system morphogenesis grooming behavior negative regulation of myeloid cell differentiation negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sensory perception of pain skeletal system morphogenesis | nucleoplasm; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MSSYFVNSLF | MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKEKLERAPETAEQGDAQKGDKK | adult locomotory behavior anterior/posterior pattern specification dorsal spinal cord development embryonic skeletal system morphogenesis grooming behavior negative regulation of myeloid cell differentiation negative regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II sensory perception of pain skeletal system morphogenesis nucleoplasm; nucleus DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation MSSYFVNSLF MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKEKLERAPETAEQGDAQKGDKK |
anterior/posterior pattern specification DNA-templated transcription embryonic skeletal system development embryonic skeletal system morphogenesis proximal/distal pattern formation regulation of transcription by RNA polymerase II | aggresome; nucleoplasm; nucleus; transcription repressor complex | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSATGPISNY | MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGDGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS | anterior/posterior pattern specification DNA-templated transcription embryonic skeletal system development embryonic skeletal system morphogenesis proximal/distal pattern formation regulation of transcription by RNA polymerase II aggresome; nucleoplasm; nucleus; transcription repressor complex DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding Mus musculus Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation MSATGPISNY MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRHYALKPDAYPGRRADCGPGDGRSYPDYMYGSPGELRDRAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS |
amyloid fibril formation cellular response to glucose starvation cellular response to sodium arsenite import into nucleus localization mRNA splicing, via spliceosome mRNA transport negative regulation of telomere maintenance via telomerase nuclear export positive regulation of telomere maintenance via telomerase regulation of alternative mRNA splicing, via spliceosome regulation of RNA splicing RNA export from nucleus | catalytic step 2 spliceosome; cytoplasm; cytosol; extracellular exosome; intracellular non-membrane-bounded organelle; membrane; nucleoplasm; nucleus; ribonucleoprotein complex; spliceosomal complex | DNA binding G-rich strand telomeric DNA binding identical protein binding miRNA binding molecular condensate scaffold activity mRNA 3'-UTR binding pre-mRNA binding protein domain specific binding RNA binding single-stranded DNA binding single-stranded RNA binding telomeric repeat-containing RNA binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Amyotrophic lateral sclerosis Cytoplasm Direct protein sequencing Disease variant Host-virus interaction Isopeptide bond Methylation mRNA processing mRNA splicing mRNA transport Neurodegeneration Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome Transport Ubl conjugation | MSKSESPKEP | MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF | amyloid fibril formation cellular response to glucose starvation cellular response to sodium arsenite import into nucleus localization mRNA splicing, via spliceosome mRNA transport negative regulation of telomere maintenance via telomerase nuclear export positive regulation of telomere maintenance via telomerase regulation of alternative mRNA splicing, via spliceosome regulation of RNA splicing RNA export from nucleus catalytic step 2 spliceosome; cytoplasm; cytosol; extracellular exosome; intracellular non-membrane-bounded organelle; membrane; nucleoplasm; nucleus; ribonucleoprotein complex; spliceosomal complex DNA binding G-rich strand telomeric DNA binding identical protein binding miRNA binding molecular condensate scaffold activity mRNA 3'-UTR binding pre-mRNA binding protein domain specific binding RNA binding single-stranded DNA binding single-stranded RNA binding telomeric repeat-containing RNA binding Homo sapiens 3D-structure Acetylation Alternative splicing Amyotrophic lateral sclerosis Cytoplasm Direct protein sequencing Disease variant Host-virus interaction Isopeptide bond Methylation mRNA processing mRNA splicing mRNA transport Neurodegeneration Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome Transport Ubl conjugation MSKSESPKEP MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF |
cellular response to peptide hormone stimulus negative regulation of calcium ion import negative regulation of nitric oxide mediated signal transduction negative regulation of peptidyl-tyrosine phosphorylation nitric oxide mediated signal transduction positive regulation of cytosolic calcium ion concentration positive regulation of epithelial cell proliferation positive regulation of pancreatic juice secretion positive regulation of peptide hormone secretion regulation of acrosome reaction regulation of store-operated calcium entry response to ethanol response to nutrient levels sperm capacitation | extracellular space | peptidase inhibitor activity serine-type endopeptidase inhibitor activity | Rattus norvegicus | Direct protein sequencing Disulfide bond Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal | MKVAIIFLLS | MKVAIIFLLSALALLSLAGNPPAEVNGKTPNCPKQIMGCPRIYDPVCGTNGITYPSECSLCFENRKFGTSIHIQRRGTC | cellular response to peptide hormone stimulus negative regulation of calcium ion import negative regulation of nitric oxide mediated signal transduction negative regulation of peptidyl-tyrosine phosphorylation nitric oxide mediated signal transduction positive regulation of cytosolic calcium ion concentration positive regulation of epithelial cell proliferation positive regulation of pancreatic juice secretion positive regulation of peptide hormone secretion regulation of acrosome reaction regulation of store-operated calcium entry response to ethanol response to nutrient levels sperm capacitation extracellular space peptidase inhibitor activity serine-type endopeptidase inhibitor activity Rattus norvegicus Direct protein sequencing Disulfide bond Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal MKVAIIFLLS MKVAIIFLLSALALLSLAGNPPAEVNGKTPNCPKQIMGCPRIYDPVCGTNGITYPSECSLCFENRKFGTSIHIQRRGTC |
monoatomic cation transport regulation of membrane potential skeletal muscle contraction | acetylcholine-gated channel complex; neuromuscular junction; neuron projection; postsynaptic membrane; postsynaptic specialization membrane; synapse | acetylcholine-gated monoatomic cation-selective channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MTMALLGTLL | MTMALLGTLLLLALFGRSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIEWQDYRLNFSKDDFAGVEILRVPSEHVWLPEIVLENNIDGQFGVAYDCNVLVYEGGSVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVELIFAVDDDGNAINKIDIDTAAFTENGEWAIDYCPGMIRHYEGGSTEDPGETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHATSPRLRQILLELLPRLLGLSPPPEDPGAASPARRASSVGILLRAEELILKKPRSELVFEGQRHRHGTWTAAALCQNLGAAAPEVRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFNQVPDLPYPPCIQP | monoatomic cation transport regulation of membrane potential skeletal muscle contraction acetylcholine-gated channel complex; neuromuscular junction; neuron projection; postsynaptic membrane; postsynaptic specialization membrane; synapse acetylcholine-gated monoatomic cation-selective channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential Rattus norvegicus Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport MTMALLGTLL MTMALLGTLLLLALFGRSQGKNEELSLYHHLFDNYDPECRPVRRPEDTVTITLKVTLTNLISLNEKEETLTTSVWIGIEWQDYRLNFSKDDFAGVEILRVPSEHVWLPEIVLENNIDGQFGVAYDCNVLVYEGGSVSWLPPAIYRSTCAVEVTYFPFDWQNCSLIFRSQTYNAEEVELIFAVDDDGNAINKIDIDTAAFTENGEWAIDYCPGMIRHYEGGSTEDPGETDVIYTLIIRRKPLFYVINIIVPCVLISGLVLLAYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRYLIFVMVVATLIVMNCVIVLNVSLRTPTTHATSPRLRQILLELLPRLLGLSPPPEDPGAASPARRASSVGILLRAEELILKKPRSELVFEGQRHRHGTWTAAALCQNLGAAAPEVRCCVDAVNFVAESTRDQEATGEELSDWVRMGKALDNVCFWAALVLFSVGSTLIFLGGYFNQVPDLPYPPCIQP |
mRNA splicing, via spliceosome RNA splicing spermatogenesis U2-type prespliceosome assembly | catalytic step 2 spliceosome; nuclear body; nuclear speck; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; spliceosomal complex; U2 snRNP; U2-type catalytic step 2 spliceosome; U2-type precatalytic spliceosome; U2-type spliceosomal complex | RNA binding U2 snRNA binding | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Isopeptide bond Leucine-rich repeat mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome Ubl conjugation | MVKLTAELIE | MVKLTAELIEQAAQYTNAVRDRELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGLDQALPCLTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMFKGKRGAQLAKDIARRSKTFNPGAGLPTDKKKGGPSPGDVEAIKNAIANASTLAEVERLKGLLQSGQIPGRERRSGPTDDGEEEMEEDTVTNGS | mRNA splicing, via spliceosome RNA splicing spermatogenesis U2-type prespliceosome assembly catalytic step 2 spliceosome; nuclear body; nuclear speck; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; spliceosomal complex; U2 snRNP; U2-type catalytic step 2 spliceosome; U2-type precatalytic spliceosome; U2-type spliceosomal complex RNA binding U2 snRNA binding Homo sapiens 3D-structure Acetylation Direct protein sequencing Isopeptide bond Leucine-rich repeat mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome Ubl conjugation MVKLTAELIE MVKLTAELIEQAAQYTNAVRDRELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGLDQALPCLTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMFKGKRGAQLAKDIARRSKTFNPGAGLPTDKKKGGPSPGDVEAIKNAIANASTLAEVERLKGLLQSGQIPGRERRSGPTDDGEEEMEEDTVTNGS |
adaptive immune response antigen processing and presentation bradykinin catabolic process cellular response to thyroid hormone stimulus dichotomous subdivision of terminal units involved in lung branching ERK1 and ERK2 cascade immune response immune response-regulating signaling pathway membrane protein proteolysis metanephros development negative regulation of apoptotic process neuropeptide catabolic process positive regulation of angiogenesis positive regulation of apoptotic signaling pathway positive regulation of cell migration positive regulation of cell population proliferation positive regulation of epithelial cell migration positive regulation of gene expression positive regulation of peptidase activity protein destabilization proteolysis proteolysis involved in protein catabolic process response to retinoic acid surfactant homeostasis T cell mediated cytotoxicity zymogen activation | alveolar lamellar body; collagen-containing extracellular matrix; cytoplasmic ribonucleoprotein granule; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; intracellular membrane-bounded organelle; lysosome; multivesicular body lumen; secretory granule lumen; tertiary granule lumen | aminopeptidase activity cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase activity cysteine-type peptidase activity endopeptidase activity HLA-A specific activating MHC class I receptor activity peptidase activity serine-type endopeptidase activity thyroid hormone binding | Homo sapiens | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Signal Thiol protease Zymogen | MWATLPLLCA | MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV | adaptive immune response antigen processing and presentation bradykinin catabolic process cellular response to thyroid hormone stimulus dichotomous subdivision of terminal units involved in lung branching ERK1 and ERK2 cascade immune response immune response-regulating signaling pathway membrane protein proteolysis metanephros development negative regulation of apoptotic process neuropeptide catabolic process positive regulation of angiogenesis positive regulation of apoptotic signaling pathway positive regulation of cell migration positive regulation of cell population proliferation positive regulation of epithelial cell migration positive regulation of gene expression positive regulation of peptidase activity protein destabilization proteolysis proteolysis involved in protein catabolic process response to retinoic acid surfactant homeostasis T cell mediated cytotoxicity zymogen activation alveolar lamellar body; collagen-containing extracellular matrix; cytoplasmic ribonucleoprotein granule; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule lumen; intracellular membrane-bounded organelle; lysosome; multivesicular body lumen; secretory granule lumen; tertiary granule lumen aminopeptidase activity cysteine-type endopeptidase activator activity involved in apoptotic process cysteine-type endopeptidase activity cysteine-type peptidase activity endopeptidase activity HLA-A specific activating MHC class I receptor activity peptidase activity serine-type endopeptidase activity thyroid hormone binding Homo sapiens 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Signal Thiol protease Zymogen MWATLPLLCA MWATLPLLCAGAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV |
adenylate cyclase-activating G protein-coupled receptor signaling pathway adult locomotory behavior digestive system development endocrine pancreas development exploration behavior female pregnancy gastric inhibitory peptide signaling pathway long-term synaptic potentiation memory positive regulation of cAMP-mediated signaling positive regulation of glucose transmembrane transport positive regulation of insulin secretion regulation of fatty acid biosynthetic process regulation of insulin secretion response to acidic pH response to amino acid response to axon injury response to glucose response to lipid response to organic cyclic compound response to peptide hormone response to selenium ion response to starvation response to xenobiotic stimulus sensory perception of pain signal transduction triglyceride homeostasis | endoplasmic reticulum lumen; extracellular region; extracellular space; neuronal cell body; secretory granule lumen | gastric inhibitory polypeptide receptor binding glucagon receptor binding hormone activity | Homo sapiens | 3D-structure Cleavage on pair of basic residues Direct protein sequencing Hormone Reference proteome Secreted Signal | MVATKTFALL | MVATKTFALLLLSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPAKNPSDEDLLRDLLIQELLACLLDQTNLCRLRSR | adenylate cyclase-activating G protein-coupled receptor signaling pathway adult locomotory behavior digestive system development endocrine pancreas development exploration behavior female pregnancy gastric inhibitory peptide signaling pathway long-term synaptic potentiation memory positive regulation of cAMP-mediated signaling positive regulation of glucose transmembrane transport positive regulation of insulin secretion regulation of fatty acid biosynthetic process regulation of insulin secretion response to acidic pH response to amino acid response to axon injury response to glucose response to lipid response to organic cyclic compound response to peptide hormone response to selenium ion response to starvation response to xenobiotic stimulus sensory perception of pain signal transduction triglyceride homeostasis endoplasmic reticulum lumen; extracellular region; extracellular space; neuronal cell body; secretory granule lumen gastric inhibitory polypeptide receptor binding glucagon receptor binding hormone activity Homo sapiens 3D-structure Cleavage on pair of basic residues Direct protein sequencing Hormone Reference proteome Secreted Signal MVATKTFALL MVATKTFALLLLSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPAKNPSDEDLLRDLLIQELLACLLDQTNLCRLRSR |
brain development diet induced thermogenesis embryonic digestive tract development hippocampus development intracellular water homeostasis negative regulation of gastrin-induced gastric acid secretion pancreatic juice secretion positive regulation of cAMP-mediated signaling positive regulation of lipid catabolic process positive regulation of pancreatic juice secretion positive regulation of somatostatin secretion regulation of appetite regulation of synaptic plasticity response to nutrient levels | extracellular region; extracellular space | digestive hormone activity G protein-coupled receptor binding hormone activity signaling receptor binding | Homo sapiens | 3D-structure Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Phosphoprotein Reference proteome Secreted Signal | MAPRPLLLLL | MAPRPLLLLLLLLGGSAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAWTRLSAGLLCPSGSNMPILQAWMPLDGTWSPWLPPGPMVSEPAGAAAEGTLRPR | brain development diet induced thermogenesis embryonic digestive tract development hippocampus development intracellular water homeostasis negative regulation of gastrin-induced gastric acid secretion pancreatic juice secretion positive regulation of cAMP-mediated signaling positive regulation of lipid catabolic process positive regulation of pancreatic juice secretion positive regulation of somatostatin secretion regulation of appetite regulation of synaptic plasticity response to nutrient levels extracellular region; extracellular space digestive hormone activity G protein-coupled receptor binding hormone activity signaling receptor binding Homo sapiens 3D-structure Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Phosphoprotein Reference proteome Secreted Signal MAPRPLLLLL MAPRPLLLLLLLLGGSAARPAPPRARRHSDGTFTSELSRLREGARLQRLLQGLVGKRSEQDAENSMAWTRLSAGLLCPSGSNMPILQAWMPLDGTWSPWLPPGPMVSEPAGAAAEGTLRPR |
behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization regulation of membrane potential signal transduction skeletal muscle contraction synaptic transmission, cholinergic | acetylcholine-gated channel complex; neuromuscular junction; neuron projection; plasma membrane; postsynaptic specialization membrane; synapse | acetylcholine binding acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity channel activity ligand-gated monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Mus musculus | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MALGALLLLL | MALGALLLLLGVLGTPLAPGARGSEAEGQLIKKLFSNYDSSVRPAREVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGLDPEGEERQEVYIHEGTFIENGQWEIIHKPSRLIQLPGDQRGGKEGHHEEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQMPFWVRQIFIHKLPPYLGLKRPKPERDQLPEPHHSLSPRSGWGRGTDEYFIRKPPSDFLFPKLNRFQPESSAPDLRRFIDGPTRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP | behavioral response to nicotine monoatomic cation transport muscle cell development muscle contraction nervous system process neuromuscular synaptic transmission postsynaptic membrane organization regulation of membrane potential signal transduction skeletal muscle contraction synaptic transmission, cholinergic acetylcholine-gated channel complex; neuromuscular junction; neuron projection; plasma membrane; postsynaptic specialization membrane; synapse acetylcholine binding acetylcholine receptor activity acetylcholine-gated monoatomic cation-selective channel activity channel activity ligand-gated monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential Mus musculus Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Phosphoprotein Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport MALGALLLLL MALGALLLLLGVLGTPLAPGARGSEAEGQLIKKLFSNYDSSVRPAREVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGLDPEGEERQEVYIHEGTFIENGQWEIIHKPSRLIQLPGDQRGGKEGHHEEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQMPFWVRQIFIHKLPPYLGLKRPKPERDQLPEPHHSLSPRSGWGRGTDEYFIRKPPSDFLFPKLNRFQPESSAPDLRRFIDGPTRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP |
adaptive immune response alpha-beta T cell activation cell surface receptor signaling pathway establishment or maintenance of cell polarity gamma-delta T cell activation positive thymic T cell selection protein transport protein-containing complex assembly regulation of lymphocyte apoptotic process T cell activation T cell receptor signaling pathway | alpha-beta T cell receptor complex; clathrin-coated endocytic vesicle membrane; cytosol; external side of plasma membrane; gamma-delta T cell receptor complex; plasma membrane | identical protein binding signaling receptor complex adaptor activity T cell receptor binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Adaptive immunity Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix | MEQGKGLAVL | MEQGKGLAVLILAIILLQGTLAQSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGKMIGFLTEDKKKWNLGSNAKDPRGMYQCKGSQNKSKPLQVYYRMCQNCIELNAATISGFLFAEIVSIFVLAVGVYFIAGQDGVRQSRASDKQTLLPNDQLYQPLKDREDDQYSHLQGNQLRRN | adaptive immune response alpha-beta T cell activation cell surface receptor signaling pathway establishment or maintenance of cell polarity gamma-delta T cell activation positive thymic T cell selection protein transport protein-containing complex assembly regulation of lymphocyte apoptotic process T cell activation T cell receptor signaling pathway alpha-beta T cell receptor complex; clathrin-coated endocytic vesicle membrane; cytosol; external side of plasma membrane; gamma-delta T cell receptor complex; plasma membrane identical protein binding signaling receptor complex adaptor activity T cell receptor binding transmembrane signaling receptor activity Homo sapiens 3D-structure Adaptive immunity Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Phosphoprotein Receptor Reference proteome Signal Transmembrane Transmembrane helix MEQGKGLAVL MEQGKGLAVLILAIILLQGTLAQSIKGNHLVKVYDYQEDGSVLLTCDAEAKNITWFKDGKMIGFLTEDKKKWNLGSNAKDPRGMYQCKGSQNKSKPLQVYYRMCQNCIELNAATISGFLFAEIVSIFVLAVGVYFIAGQDGVRQSRASDKQTLLPNDQLYQPLKDREDDQYSHLQGNQLRRN |
suppression by virus of host autophagy suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway | host cell cytoplasm; host cell nucleus; virion component | protein serine/threonine kinase inhibitor activity | Human cytomegalovirus | Host cytoplasm Host nucleus Host-virus interaction Inhibition of host autophagy by virus Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host PKR by virus Reference proteome Viral immunoevasion Virion | MAQRNGMSPR | MAQRNGMSPRPPPLGRGRGAGGPSGVGSSPPSSCVPMGAPSTAGTGASAAATTTPGHGVHRVEPRGPPGAPPSSGNNSNFWHGPERLLLSQIPVERQALTELEYQAMGAVWRAAFLANSTGRAMRKWSQRDAGTLLPLGRPYGFYARVTPRSQMNGVGATDLRQLSPRDAWIVLVATVVHEVDPAADPTLGDKAGHPEGLCAQDGLYLALGAGFRVFVYDLANNTLILAARDADEWFRHGAGEVVRLYRCNRLGVGTPRATLLPQPALRQTLLRAEEATALGRELRRRWAGTTVALQTPGRRLQPMVLLGAWQELAQYEPFASAPHPASLLTAVRRHLNQRLCCGWLALGAVLPARWLGCAAGPATGTAAGTTSPPAASGTETEAAGGDAPCAIAGAVGSAVPVPPQPYGAAGGGAICVPNADAHAVVGADAAAAAAPTVMVGSTAMAGPAASGTVPRAMLVVLLDELGAVFGYCPLDGHVYPLAAELSHFLRAGVLGALALGRESAPAAEAARRLLPELDREQWERPRWDALHLHPRAALWAREPHGQLAFLLRPGRGEAEVLTLATKHPAICANVEDYLQDARRRADAQALGLDLATVVMEAGGQMIHKKTKKPKGKEDESLMKGKHSRYTRPTEPPLTPQASLGRALRRDDEDWKPSRLPGEDSWYDLDETFWVLGSNRKNDVYQRRWKKTVLRCGLEIDRPMPTVPKGCRPQTFTHEGIQLMGGATQEPLDTGLYAPSHVTSAFVPSVYMPPTVPYPDPAARLCRDMRRVTFSNIATHYHYNAQ | suppression by virus of host autophagy suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway host cell cytoplasm; host cell nucleus; virion component protein serine/threonine kinase inhibitor activity Human cytomegalovirus Host cytoplasm Host nucleus Host-virus interaction Inhibition of host autophagy by virus Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host PKR by virus Reference proteome Viral immunoevasion Virion MAQRNGMSPR MAQRNGMSPRPPPLGRGRGAGGPSGVGSSPPSSCVPMGAPSTAGTGASAAATTTPGHGVHRVEPRGPPGAPPSSGNNSNFWHGPERLLLSQIPVERQALTELEYQAMGAVWRAAFLANSTGRAMRKWSQRDAGTLLPLGRPYGFYARVTPRSQMNGVGATDLRQLSPRDAWIVLVATVVHEVDPAADPTLGDKAGHPEGLCAQDGLYLALGAGFRVFVYDLANNTLILAARDADEWFRHGAGEVVRLYRCNRLGVGTPRATLLPQPALRQTLLRAEEATALGRELRRRWAGTTVALQTPGRRLQPMVLLGAWQELAQYEPFASAPHPASLLTAVRRHLNQRLCCGWLALGAVLPARWLGCAAGPATGTAAGTTSPPAASGTETEAAGGDAPCAIAGAVGSAVPVPPQPYGAAGGGAICVPNADAHAVVGADAAAAAAPTVMVGSTAMAGPAASGTVPRAMLVVLLDELGAVFGYCPLDGHVYPLAAELSHFLRAGVLGALALGRESAPAAEAARRLLPELDREQWERPRWDALHLHPRAALWAREPHGQLAFLLRPGRGEAEVLTLATKHPAICANVEDYLQDARRRADAQALGLDLATVVMEAGGQMIHKKTKKPKGKEDESLMKGKHSRYTRPTEPPLTPQASLGRALRRDDEDWKPSRLPGEDSWYDLDETFWVLGSNRKNDVYQRRWKKTVLRCGLEIDRPMPTVPKGCRPQTFTHEGIQLMGGATQEPLDTGLYAPSHVTSAFVPSVYMPPTVPYPDPAARLCRDMRRVTFSNIATHYHYNAQ |
homologous chromosome segregation microtubule cytoskeleton organization mitotic cell cycle mitotic sister chromatid segregation nuclear division nuclear migration along microtubule nuclear migration by microtubule mediated pushing forces | cytoplasm; microtubule; nuclear periphery; nucleus; spindle; tubulin complex | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Saccharomyces cerevisiae | 3D-structure Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREVISINVG | MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEEEF | homologous chromosome segregation microtubule cytoskeleton organization mitotic cell cycle mitotic sister chromatid segregation nuclear division nuclear migration along microtubule nuclear migration by microtubule mediated pushing forces cytoplasm; microtubule; nuclear periphery; nucleus; spindle; tubulin complex GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Saccharomyces cerevisiae 3D-structure Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome MREVISINVG MREVISINVGQAGCQIGNACWELYSLEHGIKPDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRNGPYKDLFHPEQLISGKEDAANNYARGHYTVGREILGDVLDRIRKLADQCDGLQGFLFTHSLGGGTGSGLGSLLLEELSAEYGKKSKLEFAVYPAPQVSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDMCKRNLDIPRPSFANLNNLIAQVVSSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYSPVLSKSKAFHESNSVSEITNACFEPGNQMVKCDPRDGKYMATCLLYRGDVVTRDVQRAVEQVKNKKTVQLVDWCPTGFKIGICYEPPTATPNSQLATVDRAVCMLSNTTSIAEAWKRIDRKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEEEF |
homologous chromosome segregation microtubule cytoskeleton organization mitotic cell cycle mitotic sister chromatid segregation nuclear division nuclear migration along microtubule nuclear migration by microtubule mediated pushing forces | cytoplasm; microtubule; nucleus; spindle; tubulin complex | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Saccharomyces cerevisiae | Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome | MREVISINVG | MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEF | homologous chromosome segregation microtubule cytoskeleton organization mitotic cell cycle mitotic sister chromatid segregation nuclear division nuclear migration along microtubule nuclear migration by microtubule mediated pushing forces cytoplasm; microtubule; nucleus; spindle; tubulin complex GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Saccharomyces cerevisiae Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding Reference proteome MREVISINVG MREVISINVGQAGCQIGNACWELYSLEHGIKEDGHLEDGLSKPKGGEEGFSTFFHETGYGKFVPRAIYVDLEPNVIDEVRTGRFKELFHPEQLINGKEDAANNYARGHYTVGREIVDEVEERIRKMADQCDGLQGFLFTHSLGGGTGSGLGSLLLENLSYEYGKKSKLEFAVYPAPQLSTSVVEPYNTVLTTHTTLEHADCTFMVDNEAIYDICKRNLGISRPSFSNLNGLIAQVISSVTASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVSYAPILSKKRATHESNSVSEITNACFEPGNQMVKCDPTKGKYMANCLLYRGDVVTRDVQRAVEQVKNKKTVQMVDWCPTGFKIGICYEPPSVIPSSELANVDRAVCMLSNTTAIADAWKRIDQKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALERDYIEVGADSYAEEF |
muscle contraction regulation of striated muscle contraction sarcomere organization skeletal muscle contraction | troponin complex | calcium-dependent protein binding tropomyosin binding troponin C binding troponin I binding troponin T binding | Rattus norvegicus | Acetylation Alternative splicing Muscle protein Phosphoprotein Reference proteome | MSDEETEQVE | MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK | muscle contraction regulation of striated muscle contraction sarcomere organization skeletal muscle contraction troponin complex calcium-dependent protein binding tropomyosin binding troponin C binding troponin I binding troponin T binding Rattus norvegicus Acetylation Alternative splicing Muscle protein Phosphoprotein Reference proteome MSDEETEQVE MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK |
muscle filament sliding negative regulation of ATP-dependent activity positive regulation of ATP-dependent activity regulation of heart contraction regulation of muscle contraction response to calcium ion ventricular cardiac muscle tissue morphogenesis | striated muscle thin filament; troponin complex | actin binding tropomyosin binding troponin C binding troponin I binding | Oryctolagus cuniculus | Acetylation Alternative splicing Direct protein sequencing Muscle protein Phosphoprotein Reference proteome | MSDLEEVVEE | MSDLEEVVEEYEEEQEAEEAAAEEEDWREDEDEQEAGEEEEAGGGREAEAETEETQAEEDGQEEEDKEDEDGPVEESKPKPRPFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQTLIEAHFENRKKEEEELVSLKDRIEKRRADAEQLRIRAEREKERQNRLAEERARREEEESRRKAEDEARKKKALSNMMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK | muscle filament sliding negative regulation of ATP-dependent activity positive regulation of ATP-dependent activity regulation of heart contraction regulation of muscle contraction response to calcium ion ventricular cardiac muscle tissue morphogenesis striated muscle thin filament; troponin complex actin binding tropomyosin binding troponin C binding troponin I binding Oryctolagus cuniculus Acetylation Alternative splicing Direct protein sequencing Muscle protein Phosphoprotein Reference proteome MSDLEEVVEE MSDLEEVVEEYEEEQEAEEAAAEEEDWREDEDEQEAGEEEEAGGGREAEAETEETQAEEDGQEEEDKEDEDGPVEESKPKPRPFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQTLIEAHFENRKKEEEELVSLKDRIEKRRADAEQLRIRAEREKERQNRLAEERARREEEESRRKAEDEARKKKALSNMMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK |
angiogenesis axon guidance camera-type eye morphogenesis cell chemotaxis cell-substrate adhesion central nervous system projection neuron axonogenesis cranial nerve development dendritic spine development dendritic spine morphogenesis detection of temperature stimulus involved in sensory perception of pain ephrin receptor signaling pathway establishment of cell polarity hindbrain tangential cell migration immunological synapse formation modulation of chemical synaptic transmission negative regulation of satellite cell differentiation negative regulation of skeletal muscle satellite cell proliferation neural precursor cell proliferation neurogenesis optic nerve morphogenesis phosphorylation positive regulation of synapse assembly regulation of ERK1 and ERK2 cascade regulation of JNK cascade retinal ganglion cell axon guidance skeletal muscle satellite cell activation | axon; cytoplasm; cytosol; dendrite; early endosome membrane; endoplasmic reticulum; filopodium tip; glutamatergic synapse; membrane; membrane raft; plasma membrane | ATP binding axon guidance receptor activity protein tyrosine kinase activity protein-containing complex binding transmembrane-ephrin receptor activity | Rattus norvegicus | ATP-binding Cell adhesion Cell membrane Cell projection Endosome Glycoprotein Kinase Membrane Neurogenesis Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase Ubl conjugation | MALDCLLLFL | MALDCLLLFLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKAGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA | angiogenesis axon guidance camera-type eye morphogenesis cell chemotaxis cell-substrate adhesion central nervous system projection neuron axonogenesis cranial nerve development dendritic spine development dendritic spine morphogenesis detection of temperature stimulus involved in sensory perception of pain ephrin receptor signaling pathway establishment of cell polarity hindbrain tangential cell migration immunological synapse formation modulation of chemical synaptic transmission negative regulation of satellite cell differentiation negative regulation of skeletal muscle satellite cell proliferation neural precursor cell proliferation neurogenesis optic nerve morphogenesis phosphorylation positive regulation of synapse assembly regulation of ERK1 and ERK2 cascade regulation of JNK cascade retinal ganglion cell axon guidance skeletal muscle satellite cell activation axon; cytoplasm; cytosol; dendrite; early endosome membrane; endoplasmic reticulum; filopodium tip; glutamatergic synapse; membrane; membrane raft; plasma membrane ATP binding axon guidance receptor activity protein tyrosine kinase activity protein-containing complex binding transmembrane-ephrin receptor activity Rattus norvegicus ATP-binding Cell adhesion Cell membrane Cell projection Endosome Glycoprotein Kinase Membrane Neurogenesis Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase Ubl conjugation MALDCLLLFL MALDCLLLFLLASAVAAMEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKAGYEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELREQLPLIAGSAAAGVVFVVSLVAISIVCSRKRAYSKEAVYSDKLQHYSTGRGSPGMKIYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAIKMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQSPSVMA |
bone mineralization cell differentiation defense response to Gram-positive bacterium Fc-gamma receptor signaling pathway involved in phagocytosis immune response-regulating cell surface receptor signaling pathway innate immune response integrin-mediated signaling pathway myoblast proliferation negative regulation of inflammatory response to antigenic stimulus negative regulation of natural killer cell activation peptidyl-tyrosine phosphorylation positive regulation of cell migration positive regulation of cytokine production positive regulation of mast cell degranulation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction protein autophosphorylation protein phosphorylation regulation of cell shape regulation of innate immune response regulation of phagocytosis regulation of protein kinase activity response to virus skeletal system morphogenesis transmembrane receptor protein tyrosine kinase signaling pathway | actin cytoskeleton; aggresome; cytosol; extracellular exosome; extracellular region; extrinsic component of cytoplasmic side of plasma membrane; mitochondrial inner membrane; mitochondrial intermembrane space; plasma membrane; ruffle membrane; secretory granule lumen | ATP binding Fc-gamma receptor I complex binding immunoglobulin receptor binding non-membrane spanning protein tyrosine kinase activity phosphotyrosine residue binding protein kinase binding protein tyrosine kinase activity signaling receptor binding | Homo sapiens | 3D-structure ATP-binding Cell membrane Cell projection Cytoplasm Cytoskeleton Immunity Innate immunity Kinase Lipoprotein Membrane Mitochondrion Mitochondrion inner membrane Myristate Nucleotide-binding Palmitate Phosphoprotein Proto-oncogene Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase Ubl conjugation | MGCVFCKKLE | MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT | bone mineralization cell differentiation defense response to Gram-positive bacterium Fc-gamma receptor signaling pathway involved in phagocytosis immune response-regulating cell surface receptor signaling pathway innate immune response integrin-mediated signaling pathway myoblast proliferation negative regulation of inflammatory response to antigenic stimulus negative regulation of natural killer cell activation peptidyl-tyrosine phosphorylation positive regulation of cell migration positive regulation of cytokine production positive regulation of mast cell degranulation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction protein autophosphorylation protein phosphorylation regulation of cell shape regulation of innate immune response regulation of phagocytosis regulation of protein kinase activity response to virus skeletal system morphogenesis transmembrane receptor protein tyrosine kinase signaling pathway actin cytoskeleton; aggresome; cytosol; extracellular exosome; extracellular region; extrinsic component of cytoplasmic side of plasma membrane; mitochondrial inner membrane; mitochondrial intermembrane space; plasma membrane; ruffle membrane; secretory granule lumen ATP binding Fc-gamma receptor I complex binding immunoglobulin receptor binding non-membrane spanning protein tyrosine kinase activity phosphotyrosine residue binding protein kinase binding protein tyrosine kinase activity signaling receptor binding Homo sapiens 3D-structure ATP-binding Cell membrane Cell projection Cytoplasm Cytoskeleton Immunity Innate immunity Kinase Lipoprotein Membrane Mitochondrion Mitochondrion inner membrane Myristate Nucleotide-binding Palmitate Phosphoprotein Proto-oncogene Reference proteome SH2 domain SH3 domain Transferase Tyrosine-protein kinase Ubl conjugation MGCVFCKKLE MGCVFCKKLEPVATAKEDAGLEGDFRSYGAADHYGPDPTKARPASSFAHIPNYSNFSSQAINPGFLDSGTIRGVSGIGVTLFIALYDYEARTEDDLTFTKGEKFHILNNTEGDWWEARSLSSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIMKPQTLGLAKDAWEISRSSITLERRLGTGCFGDVWLGTWNGSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDPEERPTFEYLQSFLEDYFTSAEPQYQPGDQT |
central nervous system development epithelial cell proliferation involved in Malpighian tubule morphogenesis Malpighian tubule tip cell differentiation neuroblast fate determination neuron differentiation peripheral nervous system development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of neurogenesis sensory organ development ventral cord development | RNA polymerase II transcription regulator complex; transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity sequence-specific DNA binding | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Neurogenesis Reference proteome | MTSICSSKFQ | MTSICSSKFQQQHYQLTNSNIFLLQHQHHHQTQQHQLIAPKIPLGTSQLQNMQQSQQSNVGPMLSSQKKKFNYNNMPYGEQLPSVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTASSTRHIYNSADESSNDGSSYNDYNDSLDSSQQFLTGATQSAQSHSYHSASPTPSYSGSEISGGGYIKQELQEQDLKFDSFDSFSDEQPDDEELLDYISSWQEQ | central nervous system development epithelial cell proliferation involved in Malpighian tubule morphogenesis Malpighian tubule tip cell differentiation neuroblast fate determination neuron differentiation peripheral nervous system development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of neurogenesis sensory organ development ventral cord development RNA polymerase II transcription regulator complex; transcription regulator complex DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity sequence-specific DNA binding Drosophila melanogaster Developmental protein Differentiation DNA-binding Neurogenesis Reference proteome MTSICSSKFQ MTSICSSKFQQQHYQLTNSNIFLLQHQHHHQTQQHQLIAPKIPLGTSQLQNMQQSQQSNVGPMLSSQKKKFNYNNMPYGEQLPSVARRNARERNRVKQVNNGFVNLRQHLPQTVVNSLSNGGRGSSKKLSKVDTLRIAVEYIRGLQDMLDDGTASSTRHIYNSADESSNDGSSYNDYNDSLDSSQQFLTGATQSAQSHSYHSASPTPSYSGSEISGGGYIKQELQEQDLKFDSFDSFSDEQPDDEELLDYISSWQEQ |
central nervous system development chaeta development chaeta morphogenesis epithelial cell proliferation involved in Malpighian tubule morphogenesis Malpighian tubule tip cell differentiation negative regulation of mitotic nuclear division nervous system development neuroblast fate determination neuron differentiation peripheral nervous system development positive regulation of transcription by RNA polymerase II regulation of neural precursor cell proliferation regulation of neurogenesis sensory organ development | nucleus; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity protein homodimerization activity | Drosophila melanogaster | Developmental protein Differentiation DNA-binding Neurogenesis Reference proteome | MAALSFSPSP | MAALSFSPSPPPKENPKENPNPGIKTTLKPFGKITVHNVLSESGANALQQHIANQNTIIRKIRDFGMLGAVQSAAASTTNTTPISSQRKRPLGESQKQNRHNQQNQQLSKTSVPAKKCKTNKKLAVERPPKAGTISHPHKSQSDQSFGTPGRKGLPLPQAVARRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDFPPLNSQGNSSGSGDDSFMFIKDEFDCLDEHFDDSLSNYEMDEQQTVQQTLSEDMLNPPQASDLLPSLTTLNGLQYIRIPGTNTYQLLTTDLLGDLSHEQKLEETAASGQLSRSPVPQKVVRSPCSSPVSPVASTELLLQTQTCATPLQQQVIKQEYVSTNISSSSNAQTSPQQQQQVQNLGSSPILPAFYDQEPVSFYDNVVLPGFKKEFSDILQQDQPNNTTAGCLSDESMIDAIDWWEAHAPKSNGACTNLSV | central nervous system development chaeta development chaeta morphogenesis epithelial cell proliferation involved in Malpighian tubule morphogenesis Malpighian tubule tip cell differentiation negative regulation of mitotic nuclear division nervous system development neuroblast fate determination neuron differentiation peripheral nervous system development positive regulation of transcription by RNA polymerase II regulation of neural precursor cell proliferation regulation of neurogenesis sensory organ development nucleus; RNA polymerase II transcription regulator complex DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity protein homodimerization activity Drosophila melanogaster Developmental protein Differentiation DNA-binding Neurogenesis Reference proteome MAALSFSPSP MAALSFSPSPPPKENPKENPNPGIKTTLKPFGKITVHNVLSESGANALQQHIANQNTIIRKIRDFGMLGAVQSAAASTTNTTPISSQRKRPLGESQKQNRHNQQNQQLSKTSVPAKKCKTNKKLAVERPPKAGTISHPHKSQSDQSFGTPGRKGLPLPQAVARRNARERNRVKQVNNGFALLREKIPEEVSEAFEAQGAGRGASKKLSKVETLRMAVEYIRSLEKLLGFDFPPLNSQGNSSGSGDDSFMFIKDEFDCLDEHFDDSLSNYEMDEQQTVQQTLSEDMLNPPQASDLLPSLTTLNGLQYIRIPGTNTYQLLTTDLLGDLSHEQKLEETAASGQLSRSPVPQKVVRSPCSSPVSPVASTELLLQTQTCATPLQQQVIKQEYVSTNISSSSNAQTSPQQQQQVQNLGSSPILPAFYDQEPVSFYDNVVLPGFKKEFSDILQQDQPNNTTAGCLSDESMIDAIDWWEAHAPKSNGACTNLSV |
cholesterol metabolic process lipid transport lipoprotein metabolic process peptidyl-methionine modification positive regulation of cholesterol efflux positive regulation of phagocytosis positive regulation of phospholipid efflux protein oxidation protein stabilization | high-density lipoprotein particle | amyloid-beta binding lipid binding peptide binding protein homodimerization activity | Oryctolagus cuniculus | Cholesterol metabolism Direct protein sequencing Glycoprotein HDL Lipid metabolism Lipid transport Lipoprotein Oxidation Palmitate Phosphoprotein Reference proteome Repeat Secreted Signal Steroid metabolism Sterol metabolism Transport | MKAVVLTLAV | MKAVVLTLAVLFLTGSQARHFWQRDEPRSSWDKIKDFATVYVDTVKDSGREYVAQFEASAFGKQLNLKLLDNWDSLSSTVSKLQEQLGPVTQEFWDNLEKETEGLREEMNKDLQEVRQKVQPYLDEFQKKWQEEVERYRQKVEPLGAELRESARQKLTELQEKLSPLAEELRDSARTHVDTLRTKLAPYSNELQQRLAARLESIKEGGGASLAEYQAKAREHLSVLSEKARPALEDLRQGLLPVLESFKASVQNVLDEATKKLNTQ | cholesterol metabolic process lipid transport lipoprotein metabolic process peptidyl-methionine modification positive regulation of cholesterol efflux positive regulation of phagocytosis positive regulation of phospholipid efflux protein oxidation protein stabilization high-density lipoprotein particle amyloid-beta binding lipid binding peptide binding protein homodimerization activity Oryctolagus cuniculus Cholesterol metabolism Direct protein sequencing Glycoprotein HDL Lipid metabolism Lipid transport Lipoprotein Oxidation Palmitate Phosphoprotein Reference proteome Repeat Secreted Signal Steroid metabolism Sterol metabolism Transport MKAVVLTLAV MKAVVLTLAVLFLTGSQARHFWQRDEPRSSWDKIKDFATVYVDTVKDSGREYVAQFEASAFGKQLNLKLLDNWDSLSSTVSKLQEQLGPVTQEFWDNLEKETEGLREEMNKDLQEVRQKVQPYLDEFQKKWQEEVERYRQKVEPLGAELRESARQKLTELQEKLSPLAEELRDSARTHVDTLRTKLAPYSNELQQRLAARLESIKEGGGASLAEYQAKAREHLSVLSEKARPALEDLRQGLLPVLESFKASVQNVLDEATKKLNTQ |
bone remodeling circadian rhythm mammary gland alveolus development negative regulation of ossification platelet degranulation positive regulation of fat cell differentiation regulation of hemostasis response to immobilization stress serotonin biosynthetic process serotonin biosynthetic process from tryptophan | cytoplasm; neuron projection | iron ion binding tryptophan 5-monooxygenase activity | Rattus norvegicus | Iron Metal-binding Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Serotonin biosynthesis Ubl conjugation | MIEDNKENKD | MIEDNKENKDHSSERGRVTLIFSLKNEVGGLIKALKIFQENHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFPLLKSHTTVLSVDSPDQLPEKEDVMETVPWFPKKISDLDFCANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTIFRELNKLYPTHACREYLRNLPLLSKYCGYREDNVPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEETVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELRHALSGHAKVKPFDPKVACKQECLITSFQDVYFVSESFEDAKEKMREFAKTVKRPFGVKYNPYTQSIQVLRDSKSITSAMNELRHDLDVVNDALARVSRWPSV | bone remodeling circadian rhythm mammary gland alveolus development negative regulation of ossification platelet degranulation positive regulation of fat cell differentiation regulation of hemostasis response to immobilization stress serotonin biosynthetic process serotonin biosynthetic process from tryptophan cytoplasm; neuron projection iron ion binding tryptophan 5-monooxygenase activity Rattus norvegicus Iron Metal-binding Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Serotonin biosynthesis Ubl conjugation MIEDNKENKD MIEDNKENKDHSSERGRVTLIFSLKNEVGGLIKALKIFQENHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFPLLKSHTTVLSVDSPDQLPEKEDVMETVPWFPKKISDLDFCANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTIFRELNKLYPTHACREYLRNLPLLSKYCGYREDNVPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEETVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELRHALSGHAKVKPFDPKVACKQECLITSFQDVYFVSESFEDAKEKMREFAKTVKRPFGVKYNPYTQSIQVLRDSKSITSAMNELRHDLDVVNDALARVSRWPSV |
5-phosphoribose 1-diphosphate biosynthetic process glucose homeostasis glycogen catabolic process glycogen metabolic process necroptotic process response to bacterium | cytoplasm; cytosol | AMP binding ATP binding bile acid binding carbohydrate binding glucose binding glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity purine nucleobase binding pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity vitamin binding | Rattus norvegicus | Acetylation Allosteric enzyme Carbohydrate metabolism Cytoplasm Glycogen metabolism Glycosyltransferase Nucleotide-binding Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MAKPLTDQEK | MAKPLTDQEKRRQISIRGIVGVENVAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQAGTKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEITKKTFAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFPKDIDRMRRMSLIEEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVGDDIFLREIAKVKQENKLKFSQFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPNQPDLFKDIINMLFYHDRFKVFADYEAYVKCQEKVSQLYMNQKAWNTMVLRNIAASGKFSSDRTIREYAKDIWNMEPSDLKISLSKESSNGVNANGK | 5-phosphoribose 1-diphosphate biosynthetic process glucose homeostasis glycogen catabolic process glycogen metabolic process necroptotic process response to bacterium cytoplasm; cytosol AMP binding ATP binding bile acid binding carbohydrate binding glucose binding glycogen phosphorylase activity identical protein binding linear malto-oligosaccharide phosphorylase activity purine nucleobase binding pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity vitamin binding Rattus norvegicus Acetylation Allosteric enzyme Carbohydrate metabolism Cytoplasm Glycogen metabolism Glycosyltransferase Nucleotide-binding Phosphoprotein Pyridoxal phosphate Reference proteome Transferase MAKPLTDQEK MAKPLTDQEKRRQISIRGIVGVENVAELKKGFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYDKCPKRVYYLSLEFYMGRTLQNTMINLGLQNACDEAIYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFNQKIREGWQVEEADDWLRHGNPWEKARPEFMLPVHFYGRVEHTQAGTKWVDTQVVLALPYDTPVPGYMNNTVNTMRLWSARAPNDFNLQDFNVGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDVIRRFKASKFGSKDGVGTVFDAFPDQVAIQLNDTHPALAIPELMRIFVDIEKLPWSKAWEITKKTFAYTNHTVLPEALERWPVDLVEKLLPRHLQIIYEINQKHLDRIVALFPKDIDRMRRMSLIEEEGGKRINMAHLCIVGCHAVNGVAKIHSDIVKTQVFKDFSELEPDKFQNKTNGITPRRWLLLCNPGLADLIAEKIGEDYVKDLSQLTKLHSFVGDDIFLREIAKVKQENKLKFSQFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVITMYNRIKKDPKKFFVPRTVIIGGKAAPGYHMAKMIIKLVTSVAEVVNNDPMVGSKLKVIFLENYRVSLAEKVIPATDLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEENLFIFGMRVDDVAALDKKGYEAKEYYEALPELKLVIDQIDNGFFSPNQPDLFKDIINMLFYHDRFKVFADYEAYVKCQEKVSQLYMNQKAWNTMVLRNIAASGKFSSDRTIREYAKDIWNMEPSDLKISLSKESSNGVNANGK |
glycogen catabolic process glycogen metabolic process intracellular calcium ion homeostasis response to cAMP response to hypoxia response to organic substance | cytoplasm; sarcoplasmic reticulum | AMP binding carbohydrate binding glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity | Rattus norvegicus | Acetylation Allosteric enzyme Carbohydrate metabolism Glycogen metabolism Glycosyltransferase Nucleotide-binding Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MSRPLSDQDK | MSRPLSDQDKRKQISVRGLAGVENVSDLKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVDRWIRTQQHYYAKDPKRIYYLSLELYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPPYFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDKFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELIRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEVIAERIGEEYISDLDQLRKLLSYLDDQAFIRDVAKVKQENKLKFSAYLETEYKVHINPNSLFDVQVKRIHEYKRQLLNCLHIITLYNRIKREPNRFMVPRTIMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPAVGDRFRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEDNFFIFGMRVEDVERLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMVMHHDRFKVFADYEEYIKCQDKVSELYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGLEPSRQRLPAPDEKI | glycogen catabolic process glycogen metabolic process intracellular calcium ion homeostasis response to cAMP response to hypoxia response to organic substance cytoplasm; sarcoplasmic reticulum AMP binding carbohydrate binding glycogen phosphorylase activity linear malto-oligosaccharide phosphorylase activity organic cyclic compound binding pyridoxal phosphate binding SHG alpha-glucan phosphorylase activity Rattus norvegicus Acetylation Allosteric enzyme Carbohydrate metabolism Glycogen metabolism Glycosyltransferase Nucleotide-binding Phosphoprotein Pyridoxal phosphate Reference proteome Transferase MSRPLSDQDK MSRPLSDQDKRKQISVRGLAGVENVSDLKKNFNRHLHFTLVKDRNVATPRDYYFALAHTVRDHLVDRWIRTQQHYYAKDPKRIYYLSLELYMGRTLQNTMVNLALENACDEATYQLGLDMEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKICGGWQMEEADDWLRYGNPWEKARPEFTLPVHFYGRVEHTSQGAKWVDTQVVLAMPYDTPVPGYRNNVVNTMRLWSAKAPPYFNLKDFNVGGYIQAVLDRNLAENISRVLYPNDKFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTNFDAFPDKVAIQLNDTHPSLAIPELIRILVDLERLDWDKAWDVTVKTCAYTNHTVLPEALERWPVHLMETLLPRHLQIIYEINQRFLNRVAAAFPGDVDRLRRMSLVEEGAVKRINMAHLCIAGSHAVNGVARIHSEILKKTIFKDFYELEPHKFQNKTNGITPRRWLVLCNPGLAEVIAERIGEEYISDLDQLRKLLSYLDDQAFIRDVAKVKQENKLKFSAYLETEYKVHINPNSLFDVQVKRIHEYKRQLLNCLHIITLYNRIKREPNRFMVPRTIMIGGKAAPGYHMAKMIIKLITAIGDVVNHDPAVGDRFRVIFLENYRVSLAEKVIPAADLSEQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGEDNFFIFGMRVEDVERLDQRGYNAQEYYDRIPELRQIIEQLSSGFFSPKQPDLFKDIVNMVMHHDRFKVFADYEEYIKCQDKVSELYKNPREWTRMVIRNIATSGKFSSDRTIAQYAREIWGLEPSRQRLPAPDEKI |
ammonia assimilation cycle glutamate biosynthetic process L-glutamate biosynthetic process | cytosol; glutamate synthase complex (NADPH) | 4 iron, 4 sulfur cluster binding glutamate synthase (NADPH) activity metal ion binding | Escherichia coli | 4Fe-4S Amino-acid biosynthesis Direct protein sequencing Glutamate biosynthesis Iron Iron-sulfur Metal-binding NADP Oxidoreductase Reference proteome | MSQNVYQFID | MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQADRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDRLCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLACADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTEVGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGETRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKNAREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPADAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSDLVVTAIAEGRKAADGIMNWLEV | ammonia assimilation cycle glutamate biosynthetic process L-glutamate biosynthetic process cytosol; glutamate synthase complex (NADPH) 4 iron, 4 sulfur cluster binding glutamate synthase (NADPH) activity metal ion binding Escherichia coli 4Fe-4S Amino-acid biosynthesis Direct protein sequencing Glutamate biosynthesis Iron Iron-sulfur Metal-binding NADP Oxidoreductase Reference proteome MSQNVYQFID MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQADRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDRLCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLACADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTEVGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGETRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKNAREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPADAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSDLVVTAIAEGRKAADGIMNWLEV |
signal transduction | plasma membrane | ATP binding phosphoprotein phosphatase activity phosphorelay sensor kinase activity protein dimerization activity | Escherichia coli | ATP-binding Cell inner membrane Cell membrane Hydrolase Kinase Membrane Nucleotide-binding Phosphoprotein Protein phosphatase Reference proteome Transferase Transmembrane Transmembrane helix Two-component regulatory system | MKTLFSRLIT | MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFPFGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISRYRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWHYLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALPIIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRLRELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLAADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQQGFGLTGMRERVTALGGTLHISCLHGTRVSVSLPQRYV | signal transduction plasma membrane ATP binding phosphoprotein phosphatase activity phosphorelay sensor kinase activity protein dimerization activity Escherichia coli ATP-binding Cell inner membrane Cell membrane Hydrolase Kinase Membrane Nucleotide-binding Phosphoprotein Protein phosphatase Reference proteome Transferase Transmembrane Transmembrane helix Two-component regulatory system MKTLFSRLIT MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFPFGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISRYRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWHYLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALPIIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRLRELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLAADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQQGFGLTGMRERVTALGGTLHISCLHGTRVSVSLPQRYV |
DNA metabolic process DNA modification double-strand break repair via nonhomologous end joining response to ATP | chromatin; cytosol; euchromatin; nuclear matrix; nucleoplasm; nucleus | DNA binding DNA nucleotidylexotransferase activity DNA-directed DNA polymerase activity hydrolase activity metal ion binding | Mus musculus | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Hydrolase Magnesium Metal-binding Nucleotidyltransferase Nucleus Phosphoprotein Reference proteome Terminal addition Transferase | MDPLQAVHLG | MDPLQAVHLGPRKKRPRQLGTPVASTPYDIRFRDLVLFILEKKMGTTRRAFLMELARRKGFRVENELSDSVTHIVAENNSGSDVLEWLQLQNIKASSELELLDISWLIECMGAGKPVEMMGRHQLVVNRNSSPSPVPGSQNVPAPAVKKISQYACQRRTTLNNYNQLFTDALDILAENDELRENEGSCLAFMRASSVLKSLPFPITSMKDTEGIPCLGDKVKSIIEGIIEDGESSEAKAVLNDERYKSFKLFTSVFGVGLKTAEKWFRMGFRTLSKIQSDKSLRFTQMQKAGFLYYEDLVSCVNRPEAEAVSMLVKEAVVTFLPDALVTMTGGFRRGKMTGHDVDFLITSPEATEDEEQQLLHKVTDFWKQQGLLLYCDILESTFEKFKQPSRKVDALDHFQKCFLILKLDHGRVHSEKSGQQEGKGWKAIRVDLVMCPYDRRAFALLGWTGSRQFERDLRRYATHERKMMLDNHALYDRTKRVFLEAESEEEIFAHLGLDYIEPWERNA | DNA metabolic process DNA modification double-strand break repair via nonhomologous end joining response to ATP chromatin; cytosol; euchromatin; nuclear matrix; nucleoplasm; nucleus DNA binding DNA nucleotidylexotransferase activity DNA-directed DNA polymerase activity hydrolase activity metal ion binding Mus musculus 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Hydrolase Magnesium Metal-binding Nucleotidyltransferase Nucleus Phosphoprotein Reference proteome Terminal addition Transferase MDPLQAVHLG MDPLQAVHLGPRKKRPRQLGTPVASTPYDIRFRDLVLFILEKKMGTTRRAFLMELARRKGFRVENELSDSVTHIVAENNSGSDVLEWLQLQNIKASSELELLDISWLIECMGAGKPVEMMGRHQLVVNRNSSPSPVPGSQNVPAPAVKKISQYACQRRTTLNNYNQLFTDALDILAENDELRENEGSCLAFMRASSVLKSLPFPITSMKDTEGIPCLGDKVKSIIEGIIEDGESSEAKAVLNDERYKSFKLFTSVFGVGLKTAEKWFRMGFRTLSKIQSDKSLRFTQMQKAGFLYYEDLVSCVNRPEAEAVSMLVKEAVVTFLPDALVTMTGGFRRGKMTGHDVDFLITSPEATEDEEQQLLHKVTDFWKQQGLLLYCDILESTFEKFKQPSRKVDALDHFQKCFLILKLDHGRVHSEKSGQQEGKGWKAIRVDLVMCPYDRRAFALLGWTGSRQFERDLRRYATHERKMMLDNHALYDRTKRVFLEAESEEEIFAHLGLDYIEPWERNA |
starch biosynthetic process | amyloplast; chloroplast | ADP-glucose-starch glucosyltransferase activity glycogen (starch) synthase activity starch synthase activity | Hordeum vulgare | Amyloplast Chloroplast Direct protein sequencing Glycosyltransferase Plastid Starch biosynthesis Transferase Transit peptide | MAALATSQLA | MAALATSQLATSGTVLGVTDRFRRPGFQGLRPRNPADAALGMRTIGASAAPKQSRKAHRGSRRCLSVVVSATGSGMNLVFVGAEMAPWSKTGGLGDVLGGLPPAMAANGHRVMVVSPRYDQYKDAWDTSVISEIKVADEYERVRFFHCYKRGVDRVFIDHPWFLEKVRGKTKEKIYGPDAGTDYEDNQQRFSLLCQAALEAPRILNLNNNPYFSGPYGEDVVFVCNDWHTGLLACYLKSNYQSNGIYRTAKVAFCIHNISYQGRFSFDDFAQLNLPDRFKSSFDFIDGYDKPVEGRKINWMKAGILQADKVLTVSPYYAEELISGEARGCELDNIMRLTGITGIVNGMDVSEWDPTKDKFLAVNYDITTALEAKALNKEALQAEVGLPVDRKVPLVAFIGRLEEQKGPDVMIAAIPEILKEEDVQIILLGTGKKKFEKLLKSMEEKFPGKVRAVVRFNAPLAHQMMAGADLLAVTSRFEPCGLIQLQGMRYGTPCVCASTGGLVDTIVEGKTGFHMGRLSVDCNVVEPADVKKVATTLKRAVKVVGTPAYQEMVKNCMIQDLSWKGPAKNWEDVLLELGVEGSEPGIVGEEIAPLAMENVAAP | starch biosynthetic process amyloplast; chloroplast ADP-glucose-starch glucosyltransferase activity glycogen (starch) synthase activity starch synthase activity Hordeum vulgare Amyloplast Chloroplast Direct protein sequencing Glycosyltransferase Plastid Starch biosynthesis Transferase Transit peptide MAALATSQLA MAALATSQLATSGTVLGVTDRFRRPGFQGLRPRNPADAALGMRTIGASAAPKQSRKAHRGSRRCLSVVVSATGSGMNLVFVGAEMAPWSKTGGLGDVLGGLPPAMAANGHRVMVVSPRYDQYKDAWDTSVISEIKVADEYERVRFFHCYKRGVDRVFIDHPWFLEKVRGKTKEKIYGPDAGTDYEDNQQRFSLLCQAALEAPRILNLNNNPYFSGPYGEDVVFVCNDWHTGLLACYLKSNYQSNGIYRTAKVAFCIHNISYQGRFSFDDFAQLNLPDRFKSSFDFIDGYDKPVEGRKINWMKAGILQADKVLTVSPYYAEELISGEARGCELDNIMRLTGITGIVNGMDVSEWDPTKDKFLAVNYDITTALEAKALNKEALQAEVGLPVDRKVPLVAFIGRLEEQKGPDVMIAAIPEILKEEDVQIILLGTGKKKFEKLLKSMEEKFPGKVRAVVRFNAPLAHQMMAGADLLAVTSRFEPCGLIQLQGMRYGTPCVCASTGGLVDTIVEGKTGFHMGRLSVDCNVVEPADVKKVATTLKRAVKVVGTPAYQEMVKNCMIQDLSWKGPAKNWEDVLLELGVEGSEPGIVGEEIAPLAMENVAAP |
cellular response to sodium arsenite mRNA splicing, via spliceosome mRNA transport | catalytic step 2 spliceosome; cytoplasm; nucleus; ribonucleoprotein complex | miRNA binding mRNA 3'-UTR binding | Bos taurus | Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation mRNA processing mRNA splicing mRNA transport Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome Transport Ubl conjugation | MSKSESPKEP | MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF | cellular response to sodium arsenite mRNA splicing, via spliceosome mRNA transport catalytic step 2 spliceosome; cytoplasm; nucleus; ribonucleoprotein complex miRNA binding mRNA 3'-UTR binding Bos taurus Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Methylation mRNA processing mRNA splicing mRNA transport Nucleus Phosphoprotein Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome Transport Ubl conjugation MSKSESPKEP MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF |
complement activation, classical pathway innate immune response proteolysis | blood microparticle; extracellular region; extracellular space | calcium ion binding identical protein binding serine-type endopeptidase activity | Homo sapiens | 3D-structure Calcium Complement pathway Direct protein sequencing Disease variant Disulfide bond EGF-like domain Ehlers-Danlos syndrome Glycoprotein Hydrolase Hydroxylation Immunity Innate immunity Metal-binding Protease Reference proteome Repeat Serine protease Signal Sushi | MWCIVLFSLL | MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED | complement activation, classical pathway innate immune response proteolysis blood microparticle; extracellular region; extracellular space calcium ion binding identical protein binding serine-type endopeptidase activity Homo sapiens 3D-structure Calcium Complement pathway Direct protein sequencing Disease variant Disulfide bond EGF-like domain Ehlers-Danlos syndrome Glycoprotein Hydrolase Hydroxylation Immunity Innate immunity Metal-binding Protease Reference proteome Repeat Serine protease Signal Sushi MWCIVLFSLL MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED |
proteolysis | extracellular region | serine-type endopeptidase activity toxin activity | Agkistrodon contortrix contortrix | 3D-structure Blood coagulation cascade inhibiting toxin Direct protein sequencing Disulfide bond Glycoprotein Hemostasis impairing toxin Hydrolase Protease Secreted Serine protease Toxin | VIGGDECNIN | VIGGDECNINEHRFLALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEGGKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGNTDATCPP | proteolysis extracellular region serine-type endopeptidase activity toxin activity Agkistrodon contortrix contortrix 3D-structure Blood coagulation cascade inhibiting toxin Direct protein sequencing Disulfide bond Glycoprotein Hemostasis impairing toxin Hydrolase Protease Secreted Serine protease Toxin VIGGDECNIN VIGGDECNINEHRFLALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLNKDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAATTLCAGILEGGKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGNTDATCPP |
biphenyl catabolic process cellular glucuronidation cellular response to ethanol cellular response to glucocorticoid stimulus cellular response to growth hormone stimulus cellular response to testosterone stimulus estrogen metabolic process response to lipopolysaccharide xenobiotic metabolic process | endoplasmic reticulum membrane | glucuronosyltransferase activity | Rattus norvegicus | Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Reference proteome Signal Transferase Transmembrane Transmembrane helix | MSMKQTSVFL | MSMKQTSVFLLIQLICYFRPGACGKVLVWPTEYSHWINIKIILNELAQRGHEVTVLVSSASILIEPTKESSINFEIYSVPLSKSDLEYSFAKWIDEWTRDFETLSIWTYYSKMQKVFNEYSDVVENLCKALIWNKSLMKKLQGSQFDVILADAVGPCGELLAELLKTPLVYSLRFCPGYRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKNMLQMLYFDFWFQPFKEKSWSQFYSDVLGRPTTLTEMMGKADIWLIRTFWDLEFPHPFLPNFDFVGGLHCKPAKPLPREMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANVVASALAQIPQKVVWRFDGKKPDTLGSNTRLYKWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLLLCVVGVVFIITKFCLFCCRKTANMGKKKKE | biphenyl catabolic process cellular glucuronidation cellular response to ethanol cellular response to glucocorticoid stimulus cellular response to growth hormone stimulus cellular response to testosterone stimulus estrogen metabolic process response to lipopolysaccharide xenobiotic metabolic process endoplasmic reticulum membrane glucuronosyltransferase activity Rattus norvegicus Endoplasmic reticulum Glycoprotein Glycosyltransferase Membrane Reference proteome Signal Transferase Transmembrane Transmembrane helix MSMKQTSVFL MSMKQTSVFLLIQLICYFRPGACGKVLVWPTEYSHWINIKIILNELAQRGHEVTVLVSSASILIEPTKESSINFEIYSVPLSKSDLEYSFAKWIDEWTRDFETLSIWTYYSKMQKVFNEYSDVVENLCKALIWNKSLMKKLQGSQFDVILADAVGPCGELLAELLKTPLVYSLRFCPGYRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKNMLQMLYFDFWFQPFKEKSWSQFYSDVLGRPTTLTEMMGKADIWLIRTFWDLEFPHPFLPNFDFVGGLHCKPAKPLPREMEEFVQSSGEHGVVVFSLGSMVKNLTEEKANVVASALAQIPQKVVWRFDGKKPDTLGSNTRLYKWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFSILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDLSWFQYHSLDVIGFLLLCVVGVVFIITKFCLFCCRKTANMGKKKKE |
IRE1-mediated unfolded protein response phosphorylation positive regulation of translation in response to stress regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay tRNA splicing, via endonucleolytic cleavage and ligation | cytoplasm; nuclear inner membrane; nucleus | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity ATP binding endonuclease activity GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity RNA ligase (ATP) activity | Saccharomyces cerevisiae | ATP-binding Endonuclease Hydrolase Kinase Ligase Multifunctional enzyme Nuclease Nucleotide-binding Reference proteome Transferase tRNA processing | MPSPYDGKRT | MPSPYDGKRTVTQLVNELEKAEKLSGRGRAYRRVCDLSHSNKKVISWKFNEWDYGKNTITLPCNARGLFISDDTTNPVIVARGYDKFFNVGEVNFTKWNWIEENCTGPYDVTIKANGCIIFISGLEDGTLVVCSKHSTGPRADVDRNHAEAGEKQLLRQLAAMNINRSDFARMLYTHNVTAVAEYCDDSFEEHILEYPLEKAGLYLHGVNVNKAEFETWDMKDVSQMASKYGFRCVQCITSNTLEDLKKFLDNCSATGSFEGQEIEGFVIRCHLKSTEKPFFFKYKFEEPYLMYRQWREVTKDYISNKSRVFKFRKHKFITNKYLDFAIPILESSPKICENYLKGFGVIELRNKFLQSYGMSGLEILNHEKVAELELKNAIDYDKVDERTKFLIFPISVIGCGKTTTSQTLVNLFPDSWGHIQNDDITGKDKSQLMKKSLELLSKKEIKCVIVDRNNHQFRERKQLFEWLNELKEDYLVYDTNIKVIGVSFAPYDKLSEIRDITLQRVIKRGNNHQSIKWDELGEKKVVGIMNGFLKRYQPVNLDKSPDNMFDLMIELDFGQADSSLTNAKQILNEIHKAYPILVPEIPKDDEIETAFRRSLDYKPTVRKIVGKGNNNQQKTPKLIKPTYISAKIENYDEIIELVKRCIASDAELTEKFKHLLASGKVQKELHITLGHVMSSREKEAKKLWKSYCNRYTDQITEYNNNRIENAQGSGNNQNTQVKTTDKLNFRLEKLCWDEKIIAIVVELSKDKDGCIIDENNEKIKGLCCQNKIPHITLCKLESGVKAVYSNVLCEKVESAEVDENIKVVKLDNSKEFVGSVYLNF | IRE1-mediated unfolded protein response phosphorylation positive regulation of translation in response to stress regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay tRNA splicing, via endonucleolytic cleavage and ligation cytoplasm; nuclear inner membrane; nucleus 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity ATP binding endonuclease activity GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity RNA ligase (ATP) activity Saccharomyces cerevisiae ATP-binding Endonuclease Hydrolase Kinase Ligase Multifunctional enzyme Nuclease Nucleotide-binding Reference proteome Transferase tRNA processing MPSPYDGKRT MPSPYDGKRTVTQLVNELEKAEKLSGRGRAYRRVCDLSHSNKKVISWKFNEWDYGKNTITLPCNARGLFISDDTTNPVIVARGYDKFFNVGEVNFTKWNWIEENCTGPYDVTIKANGCIIFISGLEDGTLVVCSKHSTGPRADVDRNHAEAGEKQLLRQLAAMNINRSDFARMLYTHNVTAVAEYCDDSFEEHILEYPLEKAGLYLHGVNVNKAEFETWDMKDVSQMASKYGFRCVQCITSNTLEDLKKFLDNCSATGSFEGQEIEGFVIRCHLKSTEKPFFFKYKFEEPYLMYRQWREVTKDYISNKSRVFKFRKHKFITNKYLDFAIPILESSPKICENYLKGFGVIELRNKFLQSYGMSGLEILNHEKVAELELKNAIDYDKVDERTKFLIFPISVIGCGKTTTSQTLVNLFPDSWGHIQNDDITGKDKSQLMKKSLELLSKKEIKCVIVDRNNHQFRERKQLFEWLNELKEDYLVYDTNIKVIGVSFAPYDKLSEIRDITLQRVIKRGNNHQSIKWDELGEKKVVGIMNGFLKRYQPVNLDKSPDNMFDLMIELDFGQADSSLTNAKQILNEIHKAYPILVPEIPKDDEIETAFRRSLDYKPTVRKIVGKGNNNQQKTPKLIKPTYISAKIENYDEIIELVKRCIASDAELTEKFKHLLASGKVQKELHITLGHVMSSREKEAKKLWKSYCNRYTDQITEYNNNRIENAQGSGNNQNTQVKTTDKLNFRLEKLCWDEKIIAIVVELSKDKDGCIIDENNEKIKGLCCQNKIPHITLCKLESGVKAVYSNVLCEKVESAEVDENIKVVKLDNSKEFVGSVYLNF |
bone resorption iron ion transport | extracellular region | acid phosphatase activity ferric iron binding ferrous iron binding | Sus scrofa | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Ion transport Iron Iron transport Metal-binding Reference proteome Secreted Signal Transport | MDTWTVLLIL | MDTWTVLLILQASLVLPGAVGTRTNTRTAPTPILRFVAVGDWGGVPNAPFHTAREMANAKAIATTVKTLGADFILSLGDNFYFTGVHDAKDKRFQETFEDVFSDPSLRNVPWHVLAGNHDHLGNVSAQIAYSKISKRWNFPSPYYRLRFKIPRSNVSVAIFMLDTVTLCGNSDDFVSQQPERPRNLALARTQLAWIKKQLAAAKEDYVLVAGHYPVWSIAEHGPTHCLVKQLLPLLTTHKVTAYLCGHDHNLQYLQDENGLGFVLSGAGNFMDPSKKHLRKVPNGYLRFHFGAENSLGGFAYVEITPKEMSVTYIEASGKSLFKTKLPRRARSEHQHRRA | bone resorption iron ion transport extracellular region acid phosphatase activity ferric iron binding ferrous iron binding Sus scrofa 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Ion transport Iron Iron transport Metal-binding Reference proteome Secreted Signal Transport MDTWTVLLIL MDTWTVLLILQASLVLPGAVGTRTNTRTAPTPILRFVAVGDWGGVPNAPFHTAREMANAKAIATTVKTLGADFILSLGDNFYFTGVHDAKDKRFQETFEDVFSDPSLRNVPWHVLAGNHDHLGNVSAQIAYSKISKRWNFPSPYYRLRFKIPRSNVSVAIFMLDTVTLCGNSDDFVSQQPERPRNLALARTQLAWIKKQLAAAKEDYVLVAGHYPVWSIAEHGPTHCLVKQLLPLLTTHKVTAYLCGHDHNLQYLQDENGLGFVLSGAGNFMDPSKKHLRKVPNGYLRFHFGAENSLGGFAYVEITPKEMSVTYIEASGKSLFKTKLPRRARSEHQHRRA |
cellular response to inorganic substance negative regulation of protein neddylation negative regulation of ubiquitin-dependent protein catabolic process positive regulation of gene expression positive regulation of translation protein stabilization regulation of signal transduction by p53 class mediator ribosomal large subunit biogenesis rRNA processing translation | aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; cytosolic large ribosomal subunit; cytosolic ribosome; nucleolus; nucleoplasm; nucleus; postsynaptic density; protein-containing complex; ribonucleoprotein complex; synapse | 5S rRNA binding mRNA 3'-UTR binding mRNA 5'-UTR binding mRNA binding structural constituent of ribosome ubiquitin ligase inhibitor activity ubiquitin protein ligase binding | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation | MGFVKVVKNK | MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVNGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES | cellular response to inorganic substance negative regulation of protein neddylation negative regulation of ubiquitin-dependent protein catabolic process positive regulation of gene expression positive regulation of translation protein stabilization regulation of signal transduction by p53 class mediator ribosomal large subunit biogenesis rRNA processing translation aminoacyl-tRNA synthetase multienzyme complex; cytoplasm; cytosolic large ribosomal subunit; cytosolic ribosome; nucleolus; nucleoplasm; nucleus; postsynaptic density; protein-containing complex; ribonucleoprotein complex; synapse 5S rRNA binding mRNA 3'-UTR binding mRNA 5'-UTR binding mRNA binding structural constituent of ribosome ubiquitin ligase inhibitor activity ubiquitin protein ligase binding Rattus norvegicus 3D-structure Acetylation Cytoplasm Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding Ubl conjugation MGFVKVVKNK MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVNGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAAES |
antiviral innate immune response apoptotic mitochondrial changes defense response to virus negative regulation of protein binding positive regulation of apoptotic process response to virus | cytoplasm; cytosol; endoplasmic reticulum | RNA binding | Homo sapiens | 3D-structure Acetylation Antiviral defense Apoptosis Cytoplasm Endoplasmic reticulum Immunity Innate immunity Reference proteome Repeat RNA-binding TPR repeat | MSENNKNSLE | MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE | antiviral innate immune response apoptotic mitochondrial changes defense response to virus negative regulation of protein binding positive regulation of apoptotic process response to virus cytoplasm; cytosol; endoplasmic reticulum RNA binding Homo sapiens 3D-structure Acetylation Antiviral defense Apoptosis Cytoplasm Endoplasmic reticulum Immunity Innate immunity Reference proteome Repeat RNA-binding TPR repeat MSENNKNSLE MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGE |
antiviral innate immune response cellular response to exogenous dsRNA cellular response to type I interferon defense response to virus intracellular transport of viral protein in host cell negative regulation of helicase activity negative regulation of protein binding negative regulation of viral genome replication positive regulation of viral genome replication response to virus | cytoplasm; cytosol; host cell | RNA binding | Homo sapiens | 3D-structure Alternative splicing Antiviral defense Cytoplasm Host-virus interaction Immunity Innate immunity Phosphoprotein Reference proteome Repeat RNA-binding TPR repeat Ubl conjugation | MSTNGDDHQV | MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP | antiviral innate immune response cellular response to exogenous dsRNA cellular response to type I interferon defense response to virus intracellular transport of viral protein in host cell negative regulation of helicase activity negative regulation of protein binding negative regulation of viral genome replication positive regulation of viral genome replication response to virus cytoplasm; cytosol; host cell RNA binding Homo sapiens 3D-structure Alternative splicing Antiviral defense Cytoplasm Host-virus interaction Immunity Innate immunity Phosphoprotein Reference proteome Repeat RNA-binding TPR repeat Ubl conjugation MSTNGDDHQV MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALRLAADFENSVRQGP |
adenohypophysis development adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cellular response to interleukin-6 growth hormone secretion hormone secretion multicellular organism growth negative regulation of cardiac muscle cell apoptotic process positive regulation of cAMP-mediated signaling positive regulation of cell population proliferation positive regulation of circadian sleep/wake cycle, non-REM sleep positive regulation of cytosolic calcium ion concentration positive regulation of DNA-templated transcription positive regulation of growth hormone secretion positive regulation of hormone secretion positive regulation of multicellular organism growth response to dexamethasone response to food response to hypoxia response to leptin | axon terminus; extracellular space; perikaryon; terminal bouton | growth hormone-releasing hormone activity growth hormone-releasing hormone receptor binding neuropeptide hormone activity peptide hormone receptor binding | Rattus norvegicus | Cleavage on pair of basic residues Direct protein sequencing Reference proteome Secreted Signal | MPLWVFFVLL | MPLWVFFVLLTLTSGSHCSLPPSPPFRVRRHADAIFTSSYRRILGQLYARKLLHEIMNRQQGERNQEQRSRFNRHLDRVWAEDKQMALESILQGFPRMKLSAEA | adenohypophysis development adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway cellular response to interleukin-6 growth hormone secretion hormone secretion multicellular organism growth negative regulation of cardiac muscle cell apoptotic process positive regulation of cAMP-mediated signaling positive regulation of cell population proliferation positive regulation of circadian sleep/wake cycle, non-REM sleep positive regulation of cytosolic calcium ion concentration positive regulation of DNA-templated transcription positive regulation of growth hormone secretion positive regulation of hormone secretion positive regulation of multicellular organism growth response to dexamethasone response to food response to hypoxia response to leptin axon terminus; extracellular space; perikaryon; terminal bouton growth hormone-releasing hormone activity growth hormone-releasing hormone receptor binding neuropeptide hormone activity peptide hormone receptor binding Rattus norvegicus Cleavage on pair of basic residues Direct protein sequencing Reference proteome Secreted Signal MPLWVFFVLL MPLWVFFVLLTLTSGSHCSLPPSPPFRVRRHADAIFTSSYRRILGQLYARKLLHEIMNRQQGERNQEQRSRFNRHLDRVWAEDKQMALESILQGFPRMKLSAEA |
cellular response to cytokine stimulus cellular response to lipopolysaccharide cytokine-mediated signaling pathway granulocyte colony-stimulating factor signaling pathway granulocyte differentiation immune response positive regulation of actin filament polymerization positive regulation of cell population proliferation positive regulation of myeloid cell differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of transcription by RNA polymerase II regulation of actin filament organization response to ethanol | endocytic vesicle lumen; extracellular region; extracellular space; lysosomal lumen | cytokine activity enzyme binding granulocyte colony-stimulating factor receptor binding growth factor activity | Homo sapiens | 3D-structure Alternative splicing Cytokine Direct protein sequencing Disulfide bond Glycoprotein Growth factor Pharmaceutical Reference proteome Secreted Signal | MAGPATQSPM | MAGPATQSPMKLMALQLLLWHSALWTVQEATPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLVSECATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRVLRHLAQP | cellular response to cytokine stimulus cellular response to lipopolysaccharide cytokine-mediated signaling pathway granulocyte colony-stimulating factor signaling pathway granulocyte differentiation immune response positive regulation of actin filament polymerization positive regulation of cell population proliferation positive regulation of myeloid cell differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of transcription by RNA polymerase II regulation of actin filament organization response to ethanol endocytic vesicle lumen; extracellular region; extracellular space; lysosomal lumen cytokine activity enzyme binding granulocyte colony-stimulating factor receptor binding growth factor activity Homo sapiens 3D-structure Alternative splicing Cytokine Direct protein sequencing Disulfide bond Glycoprotein Growth factor Pharmaceutical Reference proteome Secreted Signal MAGPATQSPM MAGPATQSPMKLMALQLLLWHSALWTVQEATPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLVSECATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRVLRHLAQP |
cellular response to cytokine stimulus cellular response to lipopolysaccharide granulocyte colony-stimulating factor signaling pathway granulocyte differentiation immune response positive regulation of actin filament polymerization positive regulation of cell population proliferation positive regulation of myeloid cell differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of transcription by RNA polymerase II regulation of actin filament organization response to ethanol | endocytic vesicle lumen; extracellular region; extracellular space | cytokine activity enzyme binding granulocyte colony-stimulating factor receptor binding growth factor activity | Mus musculus | Cytokine Direct protein sequencing Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal | MAQLSAQRRM | MAQLSAQRRMKLMALQLLLWQSALWSGREAVPLVTVSALPPSLPLPRSFLLKSLEQVRKIQASGSVLLEQLCATYKLCHPEELVLLGHSLGIPKASLSGCSSQALQQTQCLSQLHSGLCLYQGLLQALSGISPALAPTLDLLQLDVANFATTIWQQMENLGVAPTVQPTQSAMPAFTSAFQRRAGGVLAISYLQGFLETARLALHHLA | cellular response to cytokine stimulus cellular response to lipopolysaccharide granulocyte colony-stimulating factor signaling pathway granulocyte differentiation immune response positive regulation of actin filament polymerization positive regulation of cell population proliferation positive regulation of myeloid cell differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of transcription by RNA polymerase II regulation of actin filament organization response to ethanol endocytic vesicle lumen; extracellular region; extracellular space cytokine activity enzyme binding granulocyte colony-stimulating factor receptor binding growth factor activity Mus musculus Cytokine Direct protein sequencing Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal MAQLSAQRRM MAQLSAQRRMKLMALQLLLWQSALWSGREAVPLVTVSALPPSLPLPRSFLLKSLEQVRKIQASGSVLLEQLCATYKLCHPEELVLLGHSLGIPKASLSGCSSQALQQTQCLSQLHSGLCLYQGLLQALSGISPALAPTLDLLQLDVANFATTIWQQMENLGVAPTVQPTQSAMPAFTSAFQRRAGGVLAISYLQGFLETARLALHHLA |
defense response to virus innate immune response response to virus | cytoplasm; cytosol; endoplasmic reticulum membrane; nuclear membrane; nuclear pore; nucleus; perinuclear region of cytoplasm | GTP binding GTPase activity identical protein binding | Mus musculus | Antiviral defense Cytoplasm Endoplasmic reticulum GTP-binding Immunity Innate immunity Membrane Nucleotide-binding Nucleus Ubl conjugation | MDSVNNLCRH | MDSVNNLCRHYEEKVRPCIDLIDTLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLRKLKEGEEWRGKVSYDDIEVELSDPSEVEEAINKGQNFIAGVGLGISDKLISLDVSSPNVPDLTLIDLPGITRVAVGNQPADIGRQIKRLIKTYIQKQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGVLTKPDLVDRGAEGKVLDVMRNLVYPLKKGYMIVKCRGQQDIQEQLSLTEAFQKEQVFFKDHSYFSILLEDGKATVPCLAERLTEELTSHICKSLPLLEDQINSSHQSASEELQKYGADIPEDDRTRMSFLVNKISAFNRNIMNLIQAQETVSEGDSRLFTKLRNEFLAWDDHIEEYFKKDSPEVQSKMKEFENQYRGRELPGFVDYKAFESIIKKRVKALEESAVNMLRRVTKMVQTAFVKILSNDFGDFLNLCCTAKSKIKEIRLNQEKEAENLIRLHFQMEQIVYCQDQVYKETLKTIREKEAEKEKTKALINPATFQNNSQFPQKGLTTTEMTQHLKAYYQECRRNIGRQIPLIIQYFILKTFGEEIEKMMLQLLQDTSKCSWFLEEQSDTREKKKFLKRRLLRLDEARQKLAKFSD | defense response to virus innate immune response response to virus cytoplasm; cytosol; endoplasmic reticulum membrane; nuclear membrane; nuclear pore; nucleus; perinuclear region of cytoplasm GTP binding GTPase activity identical protein binding Mus musculus Antiviral defense Cytoplasm Endoplasmic reticulum GTP-binding Immunity Innate immunity Membrane Nucleotide-binding Nucleus Ubl conjugation MDSVNNLCRH MDSVNNLCRHYEEKVRPCIDLIDTLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLRKLKEGEEWRGKVSYDDIEVELSDPSEVEEAINKGQNFIAGVGLGISDKLISLDVSSPNVPDLTLIDLPGITRVAVGNQPADIGRQIKRLIKTYIQKQETINLVVVPSNVDIATTEALSMAQEVDPEGDRTIGVLTKPDLVDRGAEGKVLDVMRNLVYPLKKGYMIVKCRGQQDIQEQLSLTEAFQKEQVFFKDHSYFSILLEDGKATVPCLAERLTEELTSHICKSLPLLEDQINSSHQSASEELQKYGADIPEDDRTRMSFLVNKISAFNRNIMNLIQAQETVSEGDSRLFTKLRNEFLAWDDHIEEYFKKDSPEVQSKMKEFENQYRGRELPGFVDYKAFESIIKKRVKALEESAVNMLRRVTKMVQTAFVKILSNDFGDFLNLCCTAKSKIKEIRLNQEKEAENLIRLHFQMEQIVYCQDQVYKETLKTIREKEAEKEKTKALINPATFQNNSQFPQKGLTTTEMTQHLKAYYQECRRNIGRQIPLIIQYFILKTFGEEIEKMMLQLLQDTSKCSWFLEEQSDTREKKKFLKRRLLRLDEARQKLAKFSD |
dephosphorylation | extracellular region; plasma membrane; side of membrane | alkaline phosphatase activity magnesium ion binding protease binding zinc ion binding | Homo sapiens | Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc | MQGPWVLLLL | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP | dephosphorylation extracellular region; plasma membrane; side of membrane alkaline phosphatase activity magnesium ion binding protease binding zinc ion binding Homo sapiens Calcium Cell membrane Direct protein sequencing Disulfide bond Glycoprotein GPI-anchor Hydrolase Lipoprotein Magnesium Membrane Metal-binding Reference proteome Signal Zinc MQGPWVLLLL MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLGDGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLCGVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADASQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRDPTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERAGQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVFNSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHVMAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP |
hormone biosynthetic process hydrogen peroxide catabolic process response to oxidative stress thyroid hormone generation | extracellular space; membrane | calcium ion binding heme binding iodide peroxidase activity peroxidase activity | Sus scrofa | Calcium Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Heme Hydrogen peroxide Iron Membrane Metal-binding Oxidoreductase Peroxidase Reference proteome Signal Sushi Thyroid hormones biosynthesis Transmembrane Transmembrane helix | MGARAVLGVT | MGARAVLGVTLAVACAGAFFASILRRKDLLGGDTEASGVAGLVEASRLLVDEAIHTTMRRNLRKRGIFSPSQLLSFSKLPEPTSRTASRAAEIMETAVQEVKRRVCRRRDTDQLPTDVLSEELLSTIANLSGCLPHMLPPSCPHTCLANKYRLITGACNNRDHPRWGASNTALARWLPPAYEDGVTEPRGWNPHFLYNGLPLPPVREVTRQVIHVSNEAVTEDGQYSDLLMAWGQYIDHDIAFTPQSTSKAAFAGGADCQLTCENRSPCFPIQLPTNASGAAGATCLPFYRSSAACGSGRQGALVGNLSWAAPRQQMNGLTSFLDASTVYGSSPAQEQRLRNWTSAEGLLRVNTRHRDAGRAFLPFAPPPAPPACAPEPGTPAARAPCFLAGDSRASEVPGLTALHTLWLREHNRLAAAFKALNAHWSADTVYQEARKVVGALHQIVTLRDYVPKILGAEAFGQHVGPYQGYDPAVDPTVSNVFSTAAFRFGHATIHPLVRRLDARFQEHPGSHLPLRAAFFQPWRLLREGGVDPVLRGLLARPAKLQVQDQLMNEELTERLFVLSNSGTLDLASINLQRGRDHGLPGYNEWREFCGLSRLETWADLSAATANGRVADRILGLYQHPDNIDVWLGGLAESFLPGARTGPLFACIIGKQMRALRDGDRFWWENPGVFTEAQRRELSRHSMSRVICDNSGLSHVPLDAFRVGQWPQEFEPCASIQGMDLGAWREAPPSGDACGFPDPVEDGGFLLCEERGQRVLVFSCRHGFRLRGPAQITCTPRGWDSPPPLCKDINECEDETDPPCHASARCKNTKGGVLCECSDPLVLGEDGRTCVDAGRLPRASVVSIALGAVLVCGLAGLAWTVVCRWTHADARPLLPVGEGEGDGKSPSLPLPGCGNRRDVGAAPALEVEQDLSCGSRGLCE | hormone biosynthetic process hydrogen peroxide catabolic process response to oxidative stress thyroid hormone generation extracellular space; membrane calcium ion binding heme binding iodide peroxidase activity peroxidase activity Sus scrofa Calcium Direct protein sequencing Disulfide bond EGF-like domain Glycoprotein Heme Hydrogen peroxide Iron Membrane Metal-binding Oxidoreductase Peroxidase Reference proteome Signal Sushi Thyroid hormones biosynthesis Transmembrane Transmembrane helix MGARAVLGVT MGARAVLGVTLAVACAGAFFASILRRKDLLGGDTEASGVAGLVEASRLLVDEAIHTTMRRNLRKRGIFSPSQLLSFSKLPEPTSRTASRAAEIMETAVQEVKRRVCRRRDTDQLPTDVLSEELLSTIANLSGCLPHMLPPSCPHTCLANKYRLITGACNNRDHPRWGASNTALARWLPPAYEDGVTEPRGWNPHFLYNGLPLPPVREVTRQVIHVSNEAVTEDGQYSDLLMAWGQYIDHDIAFTPQSTSKAAFAGGADCQLTCENRSPCFPIQLPTNASGAAGATCLPFYRSSAACGSGRQGALVGNLSWAAPRQQMNGLTSFLDASTVYGSSPAQEQRLRNWTSAEGLLRVNTRHRDAGRAFLPFAPPPAPPACAPEPGTPAARAPCFLAGDSRASEVPGLTALHTLWLREHNRLAAAFKALNAHWSADTVYQEARKVVGALHQIVTLRDYVPKILGAEAFGQHVGPYQGYDPAVDPTVSNVFSTAAFRFGHATIHPLVRRLDARFQEHPGSHLPLRAAFFQPWRLLREGGVDPVLRGLLARPAKLQVQDQLMNEELTERLFVLSNSGTLDLASINLQRGRDHGLPGYNEWREFCGLSRLETWADLSAATANGRVADRILGLYQHPDNIDVWLGGLAESFLPGARTGPLFACIIGKQMRALRDGDRFWWENPGVFTEAQRRELSRHSMSRVICDNSGLSHVPLDAFRVGQWPQEFEPCASIQGMDLGAWREAPPSGDACGFPDPVEDGGFLLCEERGQRVLVFSCRHGFRLRGPAQITCTPRGWDSPPPLCKDINECEDETDPPCHASARCKNTKGGVLCECSDPLVLGEDGRTCVDAGRLPRASVVSIALGAVLVCGLAGLAWTVVCRWTHADARPLLPVGEGEGDGKSPSLPLPGCGNRRDVGAAPALEVEQDLSCGSRGLCE |
adult walking behavior axon target recognition axonal transport of mitochondrion cellular response to xenobiotic stimulus eating behavior male germ cell proliferation muscle cell development negative regulation of MAP kinase activity neuromuscular process proteasome-mediated ubiquitin-dependent protein catabolic process protein deubiquitination regulation of macroautophagy response to ischemia | axon cytoplasm; cytoplasm; cytosol; endoplasmic reticulum membrane; neuron projection terminus; neuronal cell body; nucleoplasm | alpha-2A adrenergic receptor binding cysteine-type deubiquitinase activity cysteine-type endopeptidase activity omega peptidase activity ubiquitin binding ubiquitin protein ligase binding | Homo sapiens | 3D-structure Cytoplasm Direct protein sequencing Disease variant Endoplasmic reticulum Glycoprotein Hereditary spastic paraplegia Hydrolase Lipoprotein Membrane Neurodegeneration Oxidation Parkinson disease Parkinsonism Phosphoprotein Prenylation Protease Reference proteome Thiol protease Ubl conjugation pathway | MQLKPMEINP | MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA | adult walking behavior axon target recognition axonal transport of mitochondrion cellular response to xenobiotic stimulus eating behavior male germ cell proliferation muscle cell development negative regulation of MAP kinase activity neuromuscular process proteasome-mediated ubiquitin-dependent protein catabolic process protein deubiquitination regulation of macroautophagy response to ischemia axon cytoplasm; cytoplasm; cytosol; endoplasmic reticulum membrane; neuron projection terminus; neuronal cell body; nucleoplasm alpha-2A adrenergic receptor binding cysteine-type deubiquitinase activity cysteine-type endopeptidase activity omega peptidase activity ubiquitin binding ubiquitin protein ligase binding Homo sapiens 3D-structure Cytoplasm Direct protein sequencing Disease variant Endoplasmic reticulum Glycoprotein Hereditary spastic paraplegia Hydrolase Lipoprotein Membrane Neurodegeneration Oxidation Parkinson disease Parkinsonism Phosphoprotein Prenylation Protease Reference proteome Thiol protease Ubl conjugation pathway MQLKPMEINP MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA |
deoxyribonucleotide biosynthetic process | cytoplasm; nucleus; ribonucleoside-diphosphate reductase complex | ferrous iron binding molecular adaptor activity protein heterodimerization activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor zinc ion binding | Saccharomyces cerevisiae | 3D-structure Deoxyribonucleotide synthesis Iron Metal-binding Nucleus Oxidoreductase Phosphoprotein Reference proteome | MPKETPSKAA | MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF | deoxyribonucleotide biosynthetic process cytoplasm; nucleus; ribonucleoside-diphosphate reductase complex ferrous iron binding molecular adaptor activity protein heterodimerization activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor zinc ion binding Saccharomyces cerevisiae 3D-structure Deoxyribonucleotide synthesis Iron Metal-binding Nucleus Oxidoreductase Phosphoprotein Reference proteome MPKETPSKAA MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF |
heme biosynthetic process positive regulation of organelle assembly protoporphyrinogen IX biosynthetic process | mitochondrial matrix; mitochondrion | 5-aminolevulinate synthase activity pyridoxal phosphate binding | Saccharomyces cerevisiae | 3D-structure Acyltransferase Heme biosynthesis Mitochondrion Pyridoxal phosphate Reference proteome Transferase Transit peptide | MQRSIFARFG | MQRSIFARFGNSSAAVSTLNRLSTTAAPHAKNGYATATGAGAAAATATASSTHAAAAAAAAANHSTQESGFDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADKVTVWCSNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQRCHIDLRTSQQKHTMYVKKAFHELGIPVIPNPSHIVPVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFNELQLPRVRDWESQGGLLGVGESGFVEESNLWTSSQLSLTNDDLNPNVRDPIVKQLEVSSGIKQ | heme biosynthetic process positive regulation of organelle assembly protoporphyrinogen IX biosynthetic process mitochondrial matrix; mitochondrion 5-aminolevulinate synthase activity pyridoxal phosphate binding Saccharomyces cerevisiae 3D-structure Acyltransferase Heme biosynthesis Mitochondrion Pyridoxal phosphate Reference proteome Transferase Transit peptide MQRSIFARFG MQRSIFARFGNSSAAVSTLNRLSTTAAPHAKNGYATATGAGAAAATATASSTHAAAAAAAAANHSTQESGFDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADKVTVWCSNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQRCHIDLRTSQQKHTMYVKKAFHELGIPVIPNPSHIVPVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFNELQLPRVRDWESQGGLLGVGESGFVEESNLWTSSQLSLTNDDLNPNVRDPIVKQLEVSSGIKQ |
neuron development neurotransmitter secretion regulation of synaptic vesicle cycle regulation of synaptic vesicle exocytosis synapse organization synaptic vesicle clustering synaptic vesicle cycle | axon; cell body; cytoskeleton; dendrite; extrinsic component of synaptic vesicle membrane; Golgi apparatus; postsynaptic density; presynapse; presynaptic active zone; Schaffer collateral - CA1 synapse; synapse; synaptic vesicle; synaptic vesicle membrane; synaptonemal complex; terminal bouton | actin binding ATP binding calcium-dependent protein binding identical protein binding protein kinase binding | Rattus norvegicus | 3D-structure Actin-binding Alternative splicing Cell projection Cytoplasmic vesicle Direct protein sequencing Glycoprotein Golgi apparatus Methylation Phosphoprotein Reference proteome Repeat Synapse | MNYLRRRLSD | MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSAAASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQRDASPGRGSHSQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPMTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQASISGPAPPKVSGASPGGQQRQGPPQKPPGPAGPIRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPTKPQLAQKPSQDVPPPIIAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD | neuron development neurotransmitter secretion regulation of synaptic vesicle cycle regulation of synaptic vesicle exocytosis synapse organization synaptic vesicle clustering synaptic vesicle cycle axon; cell body; cytoskeleton; dendrite; extrinsic component of synaptic vesicle membrane; Golgi apparatus; postsynaptic density; presynapse; presynaptic active zone; Schaffer collateral - CA1 synapse; synapse; synaptic vesicle; synaptic vesicle membrane; synaptonemal complex; terminal bouton actin binding ATP binding calcium-dependent protein binding identical protein binding protein kinase binding Rattus norvegicus 3D-structure Actin-binding Alternative splicing Cell projection Cytoplasmic vesicle Direct protein sequencing Glycoprotein Golgi apparatus Methylation Phosphoprotein Reference proteome Repeat Synapse MNYLRRRLSD MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPSAASPGATPGSAAASAERASTAAPVASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAAARVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMTQALPRQRDASPGRGSHSQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTAAPQQSASQATPMTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQASISGPAPPKVSGASPGGQQRQGPPQKPPGPAGPIRQASQAGPGPRTGPPTTQQPRPSGPGPAGRPTKPQLAQKPSQDVPPPIIAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLFSD |
heterochromatin formation positive regulation of DNA-templated transcription positive regulation of gene expression | nucleus; polytene chromosome interband | sequence-specific DNA binding | Drosophila melanogaster | 3D-structure DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MSAQGEGGGA | MSAQGEGGGAGGSGGGGAGSDGGGNAGQSSTGSGTVAVTNGGNSSAKNQLPLTPRFTAEEKEVLYTLFHLHEEVIDIKHRKKQRNKYSVRETWDKIVKDFNSHPHVSAMRNIKQIQKFWLNSRLRKQYPYRDGSSSNLSSGSAKISSVSVSVASAVPQQQQQQHHQQHDSVKVEPEYQISPDASEHNPQADTFDEIEMDANDVSEIDEDPMEQQQQQQQEAQAQAQAQAQAQAQVQSAAAEMQKMQQVNAVAAAAAANATMINTHQINVDQISAEKLTLNDLLHFKTARPREEIILIKHPEATATQIHTIPTQAQQHPMATITAGGYNQQIISEIKPQQITLAQYQAQQQQQAQAQAQAQAQAQAQAQAQAQAQAQAQQLAQQQLAAAQHQQLAAAVQVHHQQQQQQQAAVAVQQQQAAAAAAVKMQLTAATPTFTFSALPTVTAATTVPAAVPVPVATASSGSANSVAVNTSTASSVSINNTSLGGGGGNGATNSSATAADSFEERMNYFKIREAELRCKEQQLATEAKRIELNKAQDELKYMKEVHRLRVEELTMKIRILQKEEEQLRKCSTS | heterochromatin formation positive regulation of DNA-templated transcription positive regulation of gene expression nucleus; polytene chromosome interband sequence-specific DNA binding Drosophila melanogaster 3D-structure DNA-binding Nucleus Reference proteome Transcription Transcription regulation MSAQGEGGGA MSAQGEGGGAGGSGGGGAGSDGGGNAGQSSTGSGTVAVTNGGNSSAKNQLPLTPRFTAEEKEVLYTLFHLHEEVIDIKHRKKQRNKYSVRETWDKIVKDFNSHPHVSAMRNIKQIQKFWLNSRLRKQYPYRDGSSSNLSSGSAKISSVSVSVASAVPQQQQQQHHQQHDSVKVEPEYQISPDASEHNPQADTFDEIEMDANDVSEIDEDPMEQQQQQQQEAQAQAQAQAQAQAQVQSAAAEMQKMQQVNAVAAAAAANATMINTHQINVDQISAEKLTLNDLLHFKTARPREEIILIKHPEATATQIHTIPTQAQQHPMATITAGGYNQQIISEIKPQQITLAQYQAQQQQQAQAQAQAQAQAQAQAQAQAQAQAQAQQLAQQQLAAAQHQQLAAAVQVHHQQQQQQQAAVAVQQQQAAAAAAVKMQLTAATPTFTFSALPTVTAATTVPAAVPVPVATASSGSANSVAVNTSTASSVSINNTSLGGGGGNGATNSSATAADSFEERMNYFKIREAELRCKEQQLATEAKRIELNKAQDELKYMKEVHRLRVEELTMKIRILQKEEEQLRKCSTS |
G1/S transition of mitotic cell cycle positive regulation of reciprocal meiotic recombination positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription | cytoplasm; MBF transcription complex; nucleus; SBF transcription complex | DNA binding transcription coactivator activity | Saccharomyces cerevisiae | 3D-structure Activator ANK repeat Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MALEEVVRYL | MALEEVVRYLGPHNEIPLTLTRDSETGHFLLKHFLPILQQYHDTGNINETNPDSFPTDEERNKLLAHYGIAVNTDDRGELWIELEKCLQLLNMLNLFGLFQDAFEFEEPETDQDEEDPSHSKLPENKTKSENSKDNISSKRINNLQDMSLDSDAHRELGSPLKKLKIDTSVIDAESDSTPNTARGKPNDDINKGPSGDNENNGTDDNDRTAGPIITFTHDLTSDFLSSPLKIMKALPSPVVNDNEQKMKLEAFLQRLLFPEIQEMPTSLNNDSSNRNSEGGSSNQQQQHVSFDSLLQEVNDAFPNTQLNLNIPVDEHGNTPLHWLTSIANLELVKHLVKHGSNRLYGDNMGESCLVKAVKSVNNYDSGTFEALLDYLYPCLILEDSMNRTILHHIIITSGMTGCSAAAKYYLDILMGWIVKKQNRPIQSGTNEKESKPNDKNGERKDSILENLDLKWIIANMLNAQDSNGDTCLNIAARLGNISIVDALLDYGADPFIANKSGLRPVDFGAGTSKLQNTNGGDENSKMVSKGDYDGQKNGKAKKIRSQLLKNPPETTSLINDVQNLLNSISKDYENETVQYNEKLEKLHKELNEQREELANSREQLANVKQLKDEYSLMQEQLTNLKAGIEEEEESFREESKKLGIIADESSGIDWDSSEYDADEPFKVEFLSDFLEDKLQKNYEGDISKLLEAESKEQIMEQIRNQLPAEKIQSMLPPTVLLKARINAYKRNDKHLTNVLDTISTKQSELENKFRRVLSLCLKIDENKVDNMLDGLLQAISSEDPQDIDTDEMQDFLKKHAS | G1/S transition of mitotic cell cycle positive regulation of reciprocal meiotic recombination positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription cytoplasm; MBF transcription complex; nucleus; SBF transcription complex DNA binding transcription coactivator activity Saccharomyces cerevisiae 3D-structure Activator ANK repeat Cytoplasm DNA-binding Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation MALEEVVRYL MALEEVVRYLGPHNEIPLTLTRDSETGHFLLKHFLPILQQYHDTGNINETNPDSFPTDEERNKLLAHYGIAVNTDDRGELWIELEKCLQLLNMLNLFGLFQDAFEFEEPETDQDEEDPSHSKLPENKTKSENSKDNISSKRINNLQDMSLDSDAHRELGSPLKKLKIDTSVIDAESDSTPNTARGKPNDDINKGPSGDNENNGTDDNDRTAGPIITFTHDLTSDFLSSPLKIMKALPSPVVNDNEQKMKLEAFLQRLLFPEIQEMPTSLNNDSSNRNSEGGSSNQQQQHVSFDSLLQEVNDAFPNTQLNLNIPVDEHGNTPLHWLTSIANLELVKHLVKHGSNRLYGDNMGESCLVKAVKSVNNYDSGTFEALLDYLYPCLILEDSMNRTILHHIIITSGMTGCSAAAKYYLDILMGWIVKKQNRPIQSGTNEKESKPNDKNGERKDSILENLDLKWIIANMLNAQDSNGDTCLNIAARLGNISIVDALLDYGADPFIANKSGLRPVDFGAGTSKLQNTNGGDENSKMVSKGDYDGQKNGKAKKIRSQLLKNPPETTSLINDVQNLLNSISKDYENETVQYNEKLEKLHKELNEQREELANSREQLANVKQLKDEYSLMQEQLTNLKAGIEEEEESFREESKKLGIIADESSGIDWDSSEYDADEPFKVEFLSDFLEDKLQKNYEGDISKLLEAESKEQIMEQIRNQLPAEKIQSMLPPTVLLKARINAYKRNDKHLTNVLDTISTKQSELENKFRRVLSLCLKIDENKVDNMLDGLLQAISSEDPQDIDTDEMQDFLKKHAS |
leukotriene biosynthetic process lipid metabolic process peptide catabolic process protein metabolic process proteolysis response to peptide hormone response to zinc ion type I pneumocyte differentiation | cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; nucleoplasm; nucleus; tertiary granule lumen | aminopeptidase activity epoxide hydrolase activity leukotriene-A4 hydrolase activity metalloaminopeptidase activity peptidase activity RNA binding tripeptide aminopeptidase activity zinc ion binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Hydrolase Leukotriene biosynthesis Lipid metabolism Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Zinc | MPEIVDTCSL | MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD | leukotriene biosynthetic process lipid metabolic process peptide catabolic process protein metabolic process proteolysis response to peptide hormone response to zinc ion type I pneumocyte differentiation cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; nucleoplasm; nucleus; tertiary granule lumen aminopeptidase activity epoxide hydrolase activity leukotriene-A4 hydrolase activity metalloaminopeptidase activity peptidase activity RNA binding tripeptide aminopeptidase activity zinc ion binding Homo sapiens 3D-structure Acetylation Alternative splicing Cytoplasm Direct protein sequencing Hydrolase Leukotriene biosynthesis Lipid metabolism Metal-binding Metalloprotease Phosphoprotein Protease Reference proteome Zinc MPEIVDTCSL MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVTAMLVGKDLKVD |
neuropeptide signaling pathway pheromone biosynthetic process | extracellular region | myostimulatory hormone activity neuropeptide hormone activity | Bombyx mori | Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Neuropeptide Reference proteome Secreted Signal | MYKTNIVFNV | MYKTNIVFNVLALALFSIFFASCTDMKDESDRGAHSERGALWFGPRLGKRSMKPSTEDNRQTFLRLLEAADALKFYYDQLPYERQADEPETKVTKKIIFTPKLGRSVAKPQTHESLEFIPRLGRRLSEDMPATPADQEMYQPDPEEMESRTRYFSPRLGRTMSFSPRLGRELSYDYPTKYRVARSVNKTMDN | neuropeptide signaling pathway pheromone biosynthetic process extracellular region myostimulatory hormone activity neuropeptide hormone activity Bombyx mori Amidation Cleavage on pair of basic residues Direct protein sequencing Hormone Neuropeptide Reference proteome Secreted Signal MYKTNIVFNV MYKTNIVFNVLALALFSIFFASCTDMKDESDRGAHSERGALWFGPRLGKRSMKPSTEDNRQTFLRLLEAADALKFYYDQLPYERQADEPETKVTKKIIFTPKLGRSVAKPQTHESLEFIPRLGRRLSEDMPATPADQEMYQPDPEEMESRTRYFSPRLGRTMSFSPRLGRELSYDYPTKYRVARSVNKTMDN |
epithelial cell differentiation fructose 1,6-bisphosphate metabolic process fructose metabolic process gluconeogenesis glycolytic process | cytoskeleton; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; secretory granule lumen; tertiary granule lumen | cytoskeletal protein binding fructose-bisphosphate aldolase activity | Homo sapiens | 3D-structure Acetylation Glycolysis Lyase Phosphoprotein Reference proteome Schiff base | MPHSYPALSA | MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYTPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASFNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQRDNAGAATEEFIKRAEVNGLAAQGKYEGSGEDGGAAAQSLYIANHAY | epithelial cell differentiation fructose 1,6-bisphosphate metabolic process fructose metabolic process gluconeogenesis glycolytic process cytoskeleton; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; secretory granule lumen; tertiary granule lumen cytoskeletal protein binding fructose-bisphosphate aldolase activity Homo sapiens 3D-structure Acetylation Glycolysis Lyase Phosphoprotein Reference proteome Schiff base MPHSYPALSA MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLFSADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYTPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASFNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQRDNAGAATEEFIKRAEVNGLAAQGKYEGSGEDGGAAAQSLYIANHAY |
bacterial-type DNA replication DNA replication, synthesis of RNA primer DNA unwinding involved in DNA replication recombinational repair replication fork processing response to radiation | cytosol; DnaB-DnaC-Rep-PriC complex; primosome complex | 3'-5' DNA helicase activity ATP binding ATP hydrolysis activity DNA helicase activity isomerase activity protein homodimerization activity single-stranded DNA binding | Escherichia coli | 3D-structure ATP-binding DNA replication DNA-binding Helicase Hydrolase Isomerase Nucleotide-binding Reference proteome | MRLNPGQQQA | MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFPYVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK | bacterial-type DNA replication DNA replication, synthesis of RNA primer DNA unwinding involved in DNA replication recombinational repair replication fork processing response to radiation cytosol; DnaB-DnaC-Rep-PriC complex; primosome complex 3'-5' DNA helicase activity ATP binding ATP hydrolysis activity DNA helicase activity isomerase activity protein homodimerization activity single-stranded DNA binding Escherichia coli 3D-structure ATP-binding DNA replication DNA-binding Helicase Hydrolase Isomerase Nucleotide-binding Reference proteome MRLNPGQQQA MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFPYVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK |
defense response | extracellular region | sodium channel inhibitor activity toxin activity | Mesobuthus eupeus | 3D-structure Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin Voltage-gated sodium channel impairing toxin | ARDAYIAKPH | ARDAYIAKPHNCVYECYNPKGSYCNDLCTENGAESGYCQILGKYGNACWCIQLPDNVPIRIPGKCH | defense response extracellular region sodium channel inhibitor activity toxin activity Mesobuthus eupeus 3D-structure Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin Voltage-gated sodium channel impairing toxin ARDAYIAKPH ARDAYIAKPHNCVYECYNPKGSYCNDLCTENGAESGYCQILGKYGNACWCIQLPDNVPIRIPGKCH |
hemolysis in another organism localization toxin transport | extracellular space; host cell plasma membrane; membrane | calcium ion binding channel activity lipid binding toxin activity | Escherichia coli | Calcium Cytolysis Direct protein sequencing Hemolysis Host cell membrane Host membrane Lipoprotein Membrane Myristate Repeat Secreted Toxin Transmembrane Transmembrane helix Virulence | MPTITAAQIK | MPTITAAQIKSTLQSAKQSAANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQGSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNKLGGSAENIGDNLGKAGSVLSTFQNFLGTALSSMKIDELIKKQKSGGNVSSSELAKASIELINQLVDTAASLNNVNSFSQQLNKLGSVLSNTKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTGTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTRISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKPDEFQKQVFDPLKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFADIFHGADGDDHIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGGAGNNYLNGGDGDDELQVQGNSLAKNVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDIYRYLSGYGHHIIDDDGGKDDKLSLADIDFRDVAFRREGNDLIMYKAEGNVLSIGHKNGITFKNWFEKESGDISNHQIEQIFDKDGRVITPDSLKKALEYQQSNNKASYVYGNDALAYGSQGNLNPLINEISKIISAAGNFDVKEERAAASLLQLSGNASDFSYGRNSITLTASA | hemolysis in another organism localization toxin transport extracellular space; host cell plasma membrane; membrane calcium ion binding channel activity lipid binding toxin activity Escherichia coliCalcium Cytolysis Direct protein sequencing Hemolysis Host cell membrane Host membrane Lipoprotein Membrane Myristate Repeat Secreted Toxin Transmembrane Transmembrane helix Virulence MPTITAAQIK MPTITAAQIKSTLQSAKQSAANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQGSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNKLGGSAENIGDNLGKAGSVLSTFQNFLGTALSSMKIDELIKKQKSGGNVSSSELAKASIELINQLVDTAASLNNVNSFSQQLNKLGSVLSNTKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTGTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTRISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKPDEFQKQVFDPLKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFADIFHGADGDDHIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGGAGNNYLNGGDGDDELQVQGNSLAKNVLSGGKGNDKLYGSEGADLLDGGEGNDLLKGGYGNDIYRYLSGYGHHIIDDDGGKDDKLSLADIDFRDVAFRREGNDLIMYKAEGNVLSIGHKNGITFKNWFEKESGDISNHQIEQIFDKDGRVITPDSLKKALEYQQSNNKASYVYGNDALAYGSQGNLNPLINEISKIISAAGNFDVKEERAAASLLQLSGNASDFSYGRNSITLTASA |
DNA damage response heterochromatin boundary formation mitotic sister chromatid biorientation | chromosome, subtelomeric region; heterochromatin; mating-type region heterochromatin; nucleolar peripheral inclusion body; nucleosome; nucleus; pericentric heterochromatin | chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin | Schizosaccharomyces pombe | 3D-structure Acetylation Chromosome DNA-binding Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome | MARTKQTARK | MARTKQTARKSTGGKAPRKQLASKAARKAAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQEAVEAYLVSLFEDTNLCAIHGKRVTIQPKDMQLARRLRGERS | DNA damage response heterochromatin boundary formation mitotic sister chromatid biorientation chromosome, subtelomeric region; heterochromatin; mating-type region heterochromatin; nucleolar peripheral inclusion body; nucleosome; nucleus; pericentric heterochromatin chromatin-protein adaptor activity DNA binding protein heterodimerization activity structural constituent of chromatin Schizosaccharomyces pombe 3D-structure Acetylation Chromosome DNA-binding Methylation Nucleosome core Nucleus Phosphoprotein Reference proteome MARTKQTARK MARTKQTARKSTGGKAPRKQLASKAARKAAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQEAVEAYLVSLFEDTNLCAIHGKRVTIQPKDMQLARRLRGERS |
fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell | host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Lymphocytic choriomeningitis virus | 3D-structure Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell Zinc | MGQIVTMFEA | MGQIVTMFEALPHIIDEVINIVIIVLIVITGIKAVYNFATCGIFALISFLLLAGRSCGMYGLKGPDIYKGVYQFKSVEFDMSHLNLTMPNACSANNSHHYISMGTSGLELTFTNDSIISHNFCNLTSAFNKKTFDHTLMSIVSSLHLSIRGNSNYKAVSCDFNNGITIQYNLTFSDAQSAQSQCRTFRGRVLDMFRTAFGGKYMRSGWGWTGSDGKTTWCSQTSYQYLIIQNRTWENHCTYAGPFGMSRILLSQEKTKFFTRRLAGTFTWTLSDSSGVENPGGYCLTKWMILAAELKCFGNTAVAKCNVNHDAEFCDMLRLIDYNKAALSKFKEDVESALHLFKTTVNSLISDQLLMRNHLRDLMGVPYCNYSKFWYLEHAKTGETSVPKCWLVTNGSYLNETHFSDQIEQEADNMITEMLRKDYIKRQGSTPLALMDLLMFSTSAYLVSIFLHLVKIPTHRHIKGGSCPKPHRLTNKGICSCGAFKVPGVKTVWKRR | fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Lymphocytic choriomeningitis virus 3D-structure Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Transmembrane Transmembrane helix Viral attachment to host cell Viral envelope protein Viral penetration into host cytoplasm Virion Virus endocytosis by host Virus entry into host cell Zinc MGQIVTMFEA MGQIVTMFEALPHIIDEVINIVIIVLIVITGIKAVYNFATCGIFALISFLLLAGRSCGMYGLKGPDIYKGVYQFKSVEFDMSHLNLTMPNACSANNSHHYISMGTSGLELTFTNDSIISHNFCNLTSAFNKKTFDHTLMSIVSSLHLSIRGNSNYKAVSCDFNNGITIQYNLTFSDAQSAQSQCRTFRGRVLDMFRTAFGGKYMRSGWGWTGSDGKTTWCSQTSYQYLIIQNRTWENHCTYAGPFGMSRILLSQEKTKFFTRRLAGTFTWTLSDSSGVENPGGYCLTKWMILAAELKCFGNTAVAKCNVNHDAEFCDMLRLIDYNKAALSKFKEDVESALHLFKTTVNSLISDQLLMRNHLRDLMGVPYCNYSKFWYLEHAKTGETSVPKCWLVTNGSYLNETHFSDQIEQEADNMITEMLRKDYIKRQGSTPLALMDLLMFSTSAYLVSIFLHLVKIPTHRHIKGGSCPKPHRLTNKGICSCGAFKVPGVKTVWKRR |
negative stranded viral RNA replication RNA-templated viral transcription suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity | helical viral capsid; host cell cytoplasm; ribonucleoprotein complex; viral nucleocapsid | hydrolase activity metal ion binding RNA binding | Lymphocytic choriomeningitis virus | 3D-structure Capsid protein Helical capsid protein Host cytoplasm Host-virus interaction Hydrolase Inhibition of host IKBKE by virus Inhibition of host innate immune response by virus Inhibition of host RLR pathway by virus Interferon antiviral system evasion Manganese Metal-binding Reference proteome Ribonucleoprotein RNA-binding Viral immunoevasion Viral nucleoprotein Virion Zinc | MSLSKEVKSF | MSLSKEVKSFQWTQALRRELQSFTSDVKAAVIKDATNLLNGLDFSEVSNVQRIMRKEKRDDKDLQRLRSLNQTVHSLVDLKSTSKKNVLKVGRLSAEELMSLAADLEKLKAKIMRSERPQASGVYMGNLTTQQLDQRSQILQIVGMRKPQQGASGVVRVWDVKDSSLLNNQFGTMPSLTMACMAKQSQTPLNDVVQALTDLGLLYTVKYPNLNDLERLKDKHPVLGVITEQQSSINISGYNFSLGAAVKAGAALLDGGNMLESILIKPSNSEDLLKAVLGAKRKLNMFVSDQVGDRNPYENILYKVCLSGEGWPYIACRTSIVGRAWENTTIDLTSEKPAVNSPRPAPGAAGPPQVGLSYSQTMLLKDLMGGIDPNAPTWIDIEGRFNDPVEIAIFQPQNGQFIHFYREPVDQKQFKQDSKYSHGMDLADLFNAQPGLTSSVIGALPQGMVLSCQGSDDIRKLLDSQNRKDIKLIDVEMTREASREYEDKVWDKYGWLCKMHTGIVRDKKKKEITPHCALMDCIIFESASKARLPDLKTVHNILPHDLIFRGPNVVTL | negative stranded viral RNA replication RNA-templated viral transcription suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity helical viral capsid; host cell cytoplasm; ribonucleoprotein complex; viral nucleocapsid hydrolase activity metal ion binding RNA binding Lymphocytic choriomeningitis virus 3D-structure Capsid protein Helical capsid protein Host cytoplasm Host-virus interaction Hydrolase Inhibition of host IKBKE by virus Inhibition of host innate immune response by virus Inhibition of host RLR pathway by virus Interferon antiviral system evasion Manganese Metal-binding Reference proteome Ribonucleoprotein RNA-binding Viral immunoevasion Viral nucleoprotein Virion Zinc MSLSKEVKSF MSLSKEVKSFQWTQALRRELQSFTSDVKAAVIKDATNLLNGLDFSEVSNVQRIMRKEKRDDKDLQRLRSLNQTVHSLVDLKSTSKKNVLKVGRLSAEELMSLAADLEKLKAKIMRSERPQASGVYMGNLTTQQLDQRSQILQIVGMRKPQQGASGVVRVWDVKDSSLLNNQFGTMPSLTMACMAKQSQTPLNDVVQALTDLGLLYTVKYPNLNDLERLKDKHPVLGVITEQQSSINISGYNFSLGAAVKAGAALLDGGNMLESILIKPSNSEDLLKAVLGAKRKLNMFVSDQVGDRNPYENILYKVCLSGEGWPYIACRTSIVGRAWENTTIDLTSEKPAVNSPRPAPGAAGPPQVGLSYSQTMLLKDLMGGIDPNAPTWIDIEGRFNDPVEIAIFQPQNGQFIHFYREPVDQKQFKQDSKYSHGMDLADLFNAQPGLTSSVIGALPQGMVLSCQGSDDIRKLLDSQNRKDIKLIDVEMTREASREYEDKVWDKYGWLCKMHTGIVRDKKKKEITPHCALMDCIIFESASKARLPDLKTVHNILPHDLIFRGPNVVTL |
response to arsenic-containing substance | cytoplasm | arsenate reductase (thioredoxin) activity metal ion binding protein tyrosine phosphatase activity | Staphylococcus aureus | 3D-structure Arsenical resistance Cytoplasm Disulfide bond Metal-binding Oxidoreductase Plasmid Potassium Redox-active center | MDKKTIYFIC | MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVNPKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFDDPAGKEWSEFQRVRDEIKLAIEKFKLR | response to arsenic-containing substance cytoplasm arsenate reductase (thioredoxin) activity metal ion binding protein tyrosine phosphatase activity Staphylococcus aureus3D-structure Arsenical resistance Cytoplasm Disulfide bond Metal-binding Oxidoreductase Plasmid Potassium Redox-active center MDKKTIYFIC MDKKTIYFICTGNSCRSQMAEGWGKEILGEGWNVYSAGIETHGVNPKAIEAMKEVDIDISNHTSDLIDNDILKQSDLVVTLCSDADNNCPILPPNVKKEHWGFDDPAGKEWSEFQRVRDEIKLAIEKFKLR |
division septum assembly FtsZ-dependent cytokinesis protein polymerization | cell division site; cytoplasm | GTP binding GTPase activity | Staphylococcus aureus | 3D-structure Cell cycle Cell division Cytoplasm GTP-binding Nucleotide-binding Septation | MLEFEQGFNH | MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDSVSERTHTTKEDDIPSFIRNREERRSRRTRR | division septum assembly FtsZ-dependent cytokinesis protein polymerization cell division site; cytoplasm GTP binding GTPase activity Staphylococcus aureus3D-structure Cell cycle Cell division Cytoplasm GTP-binding Nucleotide-binding Septation MLEFEQGFNH MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAINTDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVTSGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDTLIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIMSNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQEAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTSVNTSSNATSKDESFTSNSSNAQATDSVSERTHTTKEDDIPSFIRNREERRSRRTRR |
glucose metabolic process glycolytic process NADH regeneration response to iron ion | catalytic complex; cytoplasm; peptidoglycan-based cell wall | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity identical protein binding NAD binding NAD+ binding NADP binding protease binding transferrin receptor activity | Staphylococcus aureus | Cytoplasm Glycolysis NAD Nucleotide-binding Oxidoreductase | MAVKVAINGF | MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK | glucose metabolic process glycolytic process NADH regeneration response to iron ion catalytic complex; cytoplasm; peptidoglycan-based cell wall glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity identical protein binding NAD binding NAD+ binding NADP binding protease binding transferrin receptor activity Staphylococcus aureusCytoplasm Glycolysis NAD Nucleotide-binding Oxidoreductase MAVKVAINGF MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVAKVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIGKVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTEDEIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAELSK |
aspartate biosynthetic process isoleucine biosynthetic process leucine biosynthetic process valine biosynthetic process | cytosol | branched-chain-amino-acid transaminase activity L-isoleucine transaminase activity L-leucine transaminase activity L-leucine:2-oxoglutarate aminotransferase activity L-valine transaminase activity | Salmonella typhimurium | Amino-acid biosynthesis Aminotransferase Branched-chain amino acid biosynthesis Direct protein sequencing Pyridoxal phosphate Reference proteome Transferase | MTTKKADYIW | MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPVVFRHREHMQRLRDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLVFVGDVGMGVNPPPGYTTDVIIAAFPWGAYLGAEALDQGIDAMVSSWNRAAPNTIPTAAKAGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSALPGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEGRCGPVTKRIQQAFFGLFTGETEDKWGWLDPVNS | aspartate biosynthetic process isoleucine biosynthetic process leucine biosynthetic process valine biosynthetic process cytosol branched-chain-amino-acid transaminase activity L-isoleucine transaminase activity L-leucine transaminase activity L-leucine:2-oxoglutarate aminotransferase activity L-valine transaminase activity Salmonella typhimurium Amino-acid biosynthesis Aminotransferase Branched-chain amino acid biosynthesis Direct protein sequencing Pyridoxal phosphate Reference proteome Transferase MTTKKADYIW MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPVVFRHREHMQRLRDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLVFVGDVGMGVNPPPGYTTDVIIAAFPWGAYLGAEALDQGIDAMVSSWNRAAPNTIPTAAKAGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSALPGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEGRCGPVTKRIQQAFFGLFTGETEDKWGWLDPVNS |
protein secretion by the type III secretion system proton motive force-driven ATP synthesis proton transmembrane transport | cytoplasm; proton-transporting ATP synthase complex, catalytic core F(1); type III protein secretion system complex | ATP binding ATP hydrolysis activity protein-exporting ATPase activity | Salmonella typhimurium | 3D-structure ATP-binding Cytoplasm Nucleotide-binding Protein transport Reference proteome Translocase Transport Virulence | MKTPRLLQYL | MKTPRLLQYLAYPQKITGPIIEAELRDVAIGELCEIRRGWHQKQVVARAQVVGLQRERTVLSLIGNAQGLSRDVVLYPTGRALSAWVGYSVLGAVLDPTGKIVERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMGIFASAGCGKTMLMHMLIEQTEADVFVIGLIGERGREVTEFVDMLRASHKKEKCVLVFATSDFPSVDRCNAAQLATTVAEYFRDQGKRVVLFIDSMTRYARALRDVALASGERPARRGYPASVFDNLPRLLERPGATSEGSITAFYTVLLESEEEADPMADEIRSILDGHLYLSRKLAGQGHYPAIDVLKSVSRVFGQVTTPTHAEQASAVRKLMTRLEELQLFIDLGEYRPGENIDNDRAMQMRDSLKAWLCQPVAQYSSFDDTLSGMNAFADQN | protein secretion by the type III secretion system proton motive force-driven ATP synthesis proton transmembrane transport cytoplasm; proton-transporting ATP synthase complex, catalytic core F(1); type III protein secretion system complex ATP binding ATP hydrolysis activity protein-exporting ATPase activity Salmonella typhimurium 3D-structure ATP-binding Cytoplasm Nucleotide-binding Protein transport Reference proteome Translocase Transport Virulence MKTPRLLQYL MKTPRLLQYLAYPQKITGPIIEAELRDVAIGELCEIRRGWHQKQVVARAQVVGLQRERTVLSLIGNAQGLSRDVVLYPTGRALSAWVGYSVLGAVLDPTGKIVERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMGIFASAGCGKTMLMHMLIEQTEADVFVIGLIGERGREVTEFVDMLRASHKKEKCVLVFATSDFPSVDRCNAAQLATTVAEYFRDQGKRVVLFIDSMTRYARALRDVALASGERPARRGYPASVFDNLPRLLERPGATSEGSITAFYTVLLESEEEADPMADEIRSILDGHLYLSRKLAGQGHYPAIDVLKSVSRVFGQVTTPTHAEQASAVRKLMTRLEELQLFIDLGEYRPGENIDNDRAMQMRDSLKAWLCQPVAQYSSFDDTLSGMNAFADQN |
ATP metabolic process biosynthetic process protein secretion by the type III secretion system proton transmembrane transport | cytoplasm; type III protein secretion system complex | ATP binding ATP hydrolysis activity identical protein binding protein-exporting ATPase activity | Shigella flexneri | 3D-structure ATP-binding Cytoplasm Nucleotide-binding Plasmid Protein transport Reference proteome Translocase Transport Virulence | MSYTKLLTQL | MSYTKLLTQLSFPNRISGPILETSLSDVSIGEICNIQAGIESNEIVARAQVVGFHDEKTILSLIGNSRGLSRQTLIKPTAQFLHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDFGEYKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR | ATP metabolic process biosynthetic process protein secretion by the type III secretion system proton transmembrane transport cytoplasm; type III protein secretion system complex ATP binding ATP hydrolysis activity identical protein binding protein-exporting ATPase activity Shigella flexneri3D-structure ATP-binding Cytoplasm Nucleotide-binding Plasmid Protein transport Reference proteome Translocase Transport Virulence MSYTKLLTQL MSYTKLLTQLSFPNRISGPILETSLSDVSIGEICNIQAGIESNEIVARAQVVGFHDEKTILSLIGNSRGLSRQTLIKPTAQFLHTQVGRGLLGAVVNPLGEVTDKFAVTDNSEILYRPVDNAPPLYSERAAIEKPFLTGIKVIDSLLTCGEGQRMGIFASAGCGKTFLMNMLIEHSGADIYVIGLIGERGREVTETVDYLKNSEKKSRCVLVYATSDYSSVDRCNAAYIATAIAEFFRTEGHKVALFIDSLTRYARALRDVALAAGESPARRGYPVSVFDSLPRLLERPGKLKAGGSITAFYTVLLEDDDFADPLAEEVRSILDGHIYLSRNLAQKGQFPAIDSLKSISRVFTQVVDEKHRIMAAAFRELLSEIEELRTIIDFGEYKPGENASQDKIYNKISVVESFLKQDYRLGFTYEQTMELIGETIR |
ethanolamine catabolic process generation of precursor metabolites and energy | ethanolamine degradation polyhedral organelle | structural molecule activity | Salmonella typhimurium | Bacterial microcompartment Reference proteome Virulence | MPALDLIRPS | MPALDLIRPSVTAMRVIASVNDGFARELKLPPHIRSLGLITADSDDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDAMVASIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGIALGDPMAYLVAPPLEATFGIDAAMKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLDIARNPVQRA | ethanolamine catabolic process generation of precursor metabolites and energy ethanolamine degradation polyhedral organelle structural molecule activity Salmonella typhimurium Bacterial microcompartment Reference proteome Virulence MPALDLIRPS MPALDLIRPSVTAMRVIASVNDGFARELKLPPHIRSLGLITADSDDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDAMVASIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGIALGDPMAYLVAPPLEATFGIDAAMKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLDIARNPVQRA |
cysteine biosynthetic process from serine | cytoplasm | cysteine synthase activity L-cysteine desulfhydrase activity | Salmonella typhimurium | 3D-structure Allosteric enzyme Amino-acid biosynthesis Cysteine biosynthesis Direct protein sequencing Pyridoxal phosphate Reference proteome Transferase | MSKIYEDNSL | MSKIYEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCRIGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKGMKGAIQKAEEIVASDPQKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFISGVGTGGTLTGVTRYIKGTKGKTDLITVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPGNLDLKLIDKVVGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ | cysteine biosynthetic process from serine cytoplasm cysteine synthase activity L-cysteine desulfhydrase activity Salmonella typhimurium 3D-structure Allosteric enzyme Amino-acid biosynthesis Cysteine biosynthesis Direct protein sequencing Pyridoxal phosphate Reference proteome Transferase MSKIYEDNSL MSKIYEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCRIGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAKGMKGAIQKAEEIVASDPQKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFISGVGTGGTLTGVTRYIKGTKGKTDLITVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPGNLDLKLIDKVVGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ |
glutamine biosynthetic process nitrogen utilization protein homooligomerization | cytoplasm; membrane | ATP binding glutamine synthetase activity manganese ion binding | Salmonella typhimurium | 3D-structure ATP-binding Cytoplasm Ligase Magnesium Manganese Metal-binding Nucleotide-binding Phosphoprotein Reference proteome | MSAEHVLTML | MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDLPPEEAKEIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV | glutamine biosynthetic process nitrogen utilization protein homooligomerization cytoplasm; membrane ATP binding glutamine synthetase activity manganese ion binding Salmonella typhimurium 3D-structure ATP-binding Cytoplasm Ligase Magnesium Manganese Metal-binding Nucleotide-binding Phosphoprotein Reference proteome MSAEHVLTML MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLAYSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDLPPEEAKEIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV |
negative regulation of DNA-templated transcription negative regulation of gene expression, epigenetic | cytosol; nucleoid; protein-DNA complex | bent DNA binding DNA-binding transcription repressor activity identical protein binding minor groove of adenine-thymine-rich DNA binding protein dimerization activity structural constituent of chromatin transcription cis-regulatory region binding | Salmonella typhimurium | 3D-structure Coiled coil Cytoplasm DNA-binding Reference proteome Repressor Transcription Transcription regulation | MSEALKILNN | MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSMAAAKSGTKAKRAARPAKYSYVDENGETKTWTGQGRTPAVIKKAMEEQGKQLEDFLIKE | negative regulation of DNA-templated transcription negative regulation of gene expression, epigenetic cytosol; nucleoid; protein-DNA complex bent DNA binding DNA-binding transcription repressor activity identical protein binding minor groove of adenine-thymine-rich DNA binding protein dimerization activity structural constituent of chromatin transcription cis-regulatory region binding Salmonella typhimurium 3D-structure Coiled coil Cytoplasm DNA-binding Reference proteome Repressor Transcription Transcription regulation MSEALKILNN MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSMAAAKSGTKAKRAARPAKYSYVDENGETKTWTGQGRTPAVIKKAMEEQGKQLEDFLIKE |
5-phosphoribose 1-diphosphate biosynthetic process phosphorylation purine nucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process | cytoplasm; ribose phosphate diphosphokinase complex | ATP binding kinase activity magnesium ion binding ribose phosphate diphosphokinase activity | Salmonella typhimurium | Allosteric enzyme ATP-binding Cytoplasm Kinase Magnesium Metal-binding Nucleotide biosynthesis Nucleotide-binding Reference proteome Transferase | MPDMKLFAGN | MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLTDEIKALPNVRTLTLSGMLAEAIRRISNEESISAMFEH | 5-phosphoribose 1-diphosphate biosynthetic process phosphorylation purine nucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process cytoplasm; ribose phosphate diphosphokinase complex ATP binding kinase activity magnesium ion binding ribose phosphate diphosphokinase activity Salmonella typhimurium Allosteric enzyme ATP-binding Cytoplasm Kinase Magnesium Metal-binding Nucleotide biosynthesis Nucleotide-binding Reference proteome Transferase MPDMKLFAGN MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLNLDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLTDEIKALPNVRTLTLSGMLAEAIRRISNEESISAMFEH |
protein secretion by the type III secretion system | cell surface; extracellular region; type III protein secretion system complex | identical protein binding | Shigella flexneri | 3D-structure Plasmid Protein transport Reference proteome Secreted Transport Virulence | MSVTVPNDDW | MSVTVPNDDWTLSSLSETFDDGTQTLQGELTLALDKLAKNPSNPQLLAEYQSKLSEYTLYRNAQSNTVKVIKDVDAAIIQNFR | protein secretion by the type III secretion system cell surface; extracellular region; type III protein secretion system complex identical protein binding Shigella flexneri3D-structure Plasmid Protein transport Reference proteome Secreted Transport Virulence MSVTVPNDDW MSVTVPNDDWTLSSLSETFDDGTQTLQGELTLALDKLAKNPSNPQLLAEYQSKLSEYTLYRNAQSNTVKVIKDVDAAIIQNFR |
cell redox homeostasis hydrogen peroxide catabolic process response to oxidative stress | cytosol | NADH-dependent peroxiredoxin activity thioredoxin peroxidase activity | Salmonella typhimurium | 3D-structure Antioxidant Cytoplasm Direct protein sequencing Disulfide bond Oxidoreductase Peroxidase Redox-active center Reference proteome | MSLINTKIKP | MSLINTKIKPFKNQAFKNGEFIEVTEKDTEGRWSVFFFYPADFTFVCPTELGDVADHYEELQKLGVDVYSVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTGALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAAHPGEVCPAKWKEGEATLAPSLDLVGKI | cell redox homeostasis hydrogen peroxide catabolic process response to oxidative stress cytosol NADH-dependent peroxiredoxin activity thioredoxin peroxidase activity Salmonella typhimurium 3D-structure Antioxidant Cytoplasm Direct protein sequencing Disulfide bond Oxidoreductase Peroxidase Redox-active center Reference proteome MSLINTKIKP MSLINTKIKPFKNQAFKNGEFIEVTEKDTEGRWSVFFFYPADFTFVCPTELGDVADHYEELQKLGVDVYSVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTGALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAAHPGEVCPAKWKEGEATLAPSLDLVGKI |
phosphoenolpyruvate-dependent sugar phosphotransferase system phosphorylation | cytoplasm | kinase activity metal ion binding | Salmonella typhimurium | Cytoplasm Kinase Metal-binding Phosphoprotein Phosphotransferase system Reference proteome Sugar transport Transferase Transport Zinc | MGLFDKLKSL | MGLFDKLKSLVSDDKKDTGTIEIVAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGIELFVHFGIDTVELKGEGFKRIAEEGQRVKVGDPVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVGETPVIRIKK | phosphoenolpyruvate-dependent sugar phosphotransferase system phosphorylation cytoplasm kinase activity metal ion binding Salmonella typhimurium Cytoplasm Kinase Metal-binding Phosphoprotein Phosphotransferase system Reference proteome Sugar transport Transferase Transport Zinc MGLFDKLKSL MGLFDKLKSLVSDDKKDTGTIEIVAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGIELFVHFGIDTVELKGEGFKRIAEEGQRVKVGDPVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVGETPVIRIKK |
archaeal or bacterial-type flagellum-dependent cell motility chemotaxis phosphorelay signal transduction system | cytoplasm | metal ion binding | Salmonella typhimurium | 3D-structure Acetylation Chemotaxis Cytoplasm Flagellar rotation Magnesium Metal-binding Phosphoprotein Reference proteome Two-component regulatory system | MADKELKFLV | MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGFGFIISDWNMPNMDGLELLKTIRADSAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM | archaeal or bacterial-type flagellum-dependent cell motility chemotaxis phosphorelay signal transduction system cytoplasm metal ion binding Salmonella typhimurium 3D-structure Acetylation Chemotaxis Cytoplasm Flagellar rotation Magnesium Metal-binding Phosphoprotein Reference proteome Two-component regulatory system MADKELKFLV MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGFGFIISDWNMPNMDGLELLKTIRADSAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM |
DNA topological change DNA-templated DNA replication response to antibiotic | chromosome; cytoplasm | ATP binding DNA binding DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity metal ion binding | Salmonella typhimurium | Antibiotic resistance ATP-binding Cytoplasm DNA-binding Isomerase Magnesium Metal-binding Nucleotide-binding Reference proteome Topoisomerase | MSNSYDSSSI | MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPTGIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDTDKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTRRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQTVTRWVNALITELNEKEQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFVTGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFEQALEWLVKESRRGLAIQRYKGLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAANIDI | DNA topological change DNA-templated DNA replication response to antibiotic chromosome; cytoplasm ATP binding DNA binding DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity metal ion binding Salmonella typhimurium Antibiotic resistance ATP-binding Cytoplasm DNA-binding Isomerase Magnesium Metal-binding Nucleotide-binding Reference proteome Topoisomerase MSNSYDSSSI MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPTGIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDTDKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMTRRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATLHANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQTVTRWVNALITELNEKEQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFVTGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFEQALEWLVKESRRGLAIQRYKGLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAANIDI |
tryptophan biosynthetic process | cytoplasm | identical protein binding tryptophan synthase activity | Salmonella typhimurium | 3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis Lyase Pyridoxal phosphate Reference proteome Tryptophan biosynthesis | MTTLLNPYFG | MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI | tryptophan biosynthetic process cytoplasm identical protein binding tryptophan synthase activity Salmonella typhimurium 3D-structure Amino-acid biosynthesis Aromatic amino acid biosynthesis Lyase Pyridoxal phosphate Reference proteome Tryptophan biosynthesis MTTLLNPYFG MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQFADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVHSGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI |
arginine metabolic process carbamoyl phosphate catabolic process phosphorylation | cytoplasm | ATP binding carbamate kinase activity | Enterococcus faecium | 3D-structure Arginine metabolism ATP-binding Cytoplasm Direct protein sequencing Kinase Nucleotide-binding Transferase | MGKKMVVALG | MGKKMVVALGGNAILSNDASAHAQQQALVQTSAYLVHLIKQGHRLIVSHGNGPQVGNLLLQQQAADSEKNPAMPLDTCVAMTQGSIGYWLSNALNQELNKAGIKKQVATVLTQVVVDPADEAFKNPTKPIGPFLTEAEAKEAMQAGAIFKEDAGRGWRKVVPSPKPIDIHEAETINTLIKNDIITISCGGGGIPVVGQELKGVEAVIDKDFASEKLAELVDADALVILTGVDYVCINYGKPDEKQLTNVTVAELEEYKQAGHFAPGSMLPKIEAAIQFVESQPNKQAIITSLENLGSMSGDEIVGTVVTK | arginine metabolic process carbamoyl phosphate catabolic process phosphorylation cytoplasm ATP binding carbamate kinase activity Enterococcus faecium 3D-structure Arginine metabolism ATP-binding Cytoplasm Direct protein sequencing Kinase Nucleotide-binding Transferase MGKKMVVALG MGKKMVVALGGNAILSNDASAHAQQQALVQTSAYLVHLIKQGHRLIVSHGNGPQVGNLLLQQQAADSEKNPAMPLDTCVAMTQGSIGYWLSNALNQELNKAGIKKQVATVLTQVVVDPADEAFKNPTKPIGPFLTEAEAKEAMQAGAIFKEDAGRGWRKVVPSPKPIDIHEAETINTLIKNDIITISCGGGGIPVVGQELKGVEAVIDKDFASEKLAELVDADALVILTGVDYVCINYGKPDEKQLTNVTVAELEEYKQAGHFAPGSMLPKIEAAIQFVESQPNKQAIITSLENLGSMSGDEIVGTVVTK |
photosynthesis, light reaction respiratory electron transport chain | photosystem II; plasma membrane-derived thylakoid membrane | electron transfer activity heme binding iron ion binding | Thermosynechococcus vestitus | 3D-structure Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Photosynthesis Photosystem II Reference proteome Signal Thylakoid Transport | MLKKCVWLAV | MLKKCVWLAVALCLCLWQFTMGTALAAELTPEVLTVPLNSEGKTITLTEKQYLEGKRLFQYACASCHVGGITKTNPSLDLRTETLALATPPRDNIEGLVDYMKNPTTYDGEQEIAEVHPSLRSADIFPKMRNLTEKDLVAIAGHILVEPKILGDKWGGGKVYY | photosynthesis, light reaction respiratory electron transport chain photosystem II; plasma membrane-derived thylakoid membrane electron transfer activity heme binding iron ion binding Thermosynechococcus vestitus 3D-structure Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Photosynthesis Photosystem II Reference proteome Signal Thylakoid Transport MLKKCVWLAV MLKKCVWLAVALCLCLWQFTMGTALAAELTPEVLTVPLNSEGKTITLTEKQYLEGKRLFQYACASCHVGGITKTNPSLDLRTETLALATPPRDNIEGLVDYMKNPTTYDGEQEIAEVHPSLRSADIFPKMRNLTEKDLVAIAGHILVEPKILGDKWGGGKVYY |
photosynthesis, light reaction respiratory electron transport chain | photosystem II; plasma membrane-derived thylakoid membrane | electron transfer activity heme binding iron ion binding | Thermostichus vulcanus | 3D-structure Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Photosynthesis Photosystem II Signal Thylakoid Transport | MLKKCVWLAV | MLKKCVWLAVALCLCLWQFTMGTALAAELTPEVLTVPLNSEGKTITLTEKQYLEGKRLFQYACASCHVGGITKTNPSLDLRTETLALATPPRDNIEGLVDYMKNPTTYDGEQEIAEVHPSLRSADIFPKMRNLTEKDLVAIAGHILVEPKILGDKWGGGKVYY | photosynthesis, light reaction respiratory electron transport chain photosystem II; plasma membrane-derived thylakoid membrane electron transfer activity heme binding iron ion binding Thermostichus vulcanus 3D-structure Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Photosynthesis Photosystem II Signal Thylakoid Transport MLKKCVWLAV MLKKCVWLAVALCLCLWQFTMGTALAAELTPEVLTVPLNSEGKTITLTEKQYLEGKRLFQYACASCHVGGITKTNPSLDLRTETLALATPPRDNIEGLVDYMKNPTTYDGEQEIAEVHPSLRSADIFPKMRNLTEKDLVAIAGHILVEPKILGDKWGGGKVYY |
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