Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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carbohydrate catabolic process glycolipid catabolic process glycoside catabolic process oligosaccharide metabolic process | cytoplasm; extracellular exosome; lysosome | alpha-galactosidase activity alpha-N-acetylgalactosaminidase activity protein homodimerization activity | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Disulfide bond Epilepsy Glycoprotein Glycosidase Hydrolase Lipid metabolism Lysosome Phosphoprotein Reference proteome Signal | MLLKTVLLLG | MLLKTVLLLGHVAQVLMLDNGLLQTPPMGWLAWERFRCNINCDEDPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIGGRDASGRLMPDPKRFPHGIPFLADYVHSLGLKLGIYADMGNFTCMGYPGTTLDKVVQDAQTFAEWKVDMLKLDGCFSTPEERAQGYPKMAAALNATGRPIAFSCSWPAYEGGLPPRVNYSLLADICNLWRNYDDIQDSWWSVLSILNWFVEHQDILQPVAGPGHWNDPDMLLIGNFGLSLEQSRAQMALWTVLAAPLLMSTDLRTISAQNMDILQNPLMIKINQDPLGIQGRRIHKE... | carbohydrate catabolic process glycolipid catabolic process glycoside catabolic process oligosaccharide metabolic process cytoplasm; extracellular exosome; lysosome alpha-galactosidase activity alpha-N-acetylgalactosaminidase activity protein homodimerization activity Homo sapiens 3D-structure Direct protein sequencing... |
cytidine transport cytosine transport purine-containing compound transmembrane transport | cell periphery; fungal-type vacuole membrane; plasma membrane | cytidine transmembrane transporter activity nucleobase transmembrane transporter activity | Saccharomyces cerevisiae | Isopeptide bond Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport Ubl conjugation | MLEEGNNVYE | MLEEGNNVYEIQDLEKRSPVIGSSLENEKKVAASETFTATSEDDQQYIVESSEATKLSWFHKFFASLNAETKGVEPVTEDEKTDDSILNAASMWFSANMVIASYALGALGPMVFGLNFGQSVLVIIFFNIMGLIFVAFFSVFGAELGLRQMILSRYLVGNVTARIFSLINVIACVGWGIVNTSVSAQLLNMVNEGSGHVCPIWAGCLIIIGGTVLVTFFGYSVIHAYEKWSWVPNFAVFLVIIAQLSRSGKFKGGEWVGGATTAGSVLSFGSSIFGFAAGWTTYAADYTVYMPKSTNKYKIFFSLVAGLAFPLFFTMILG... | cytidine transport cytosine transport purine-containing compound transmembrane transport cell periphery; fungal-type vacuole membrane; plasma membrane cytidine transmembrane transporter activity nucleobase transmembrane transporter activity Saccharomyces cerevisiae Isopeptide bond Membrane Phosphoprotein Reference pro... |
autophagy exocytosis protein transport | cell tip; cellular bud neck; cellular bud tip; cytosol; Golgi to plasma membrane transport vesicle; mating projection tip; transport vesicle | guanyl-nucleotide exchange factor activity identical protein binding phosphatidylinositol-4-phosphate binding | Saccharomyces cerevisiae | 3D-structure Acetylation Coiled coil Cytoplasmic vesicle Guanine-nucleotide releasing factor Phosphoprotein Protein transport Reference proteome Transport | MDASEEAKRV | MDASEEAKRVSIQVTSLSTQLIESVDKQSHLEEQLNKSLKTIASQKAAIENYNQLKEDYNTLKRELSDRDDEVKRLREDIAKENELRTKAEEEADKLNKEVEDLTASLFDEANNMVADARKEKYAIEILNKRLTEQLREKDTLLDTLTLQLKNLKKVMHSLDNESTVTNNSNRYSTILSDSATSSSTSLNKVPTSYSLASQDIYSGIVYSPSISSIRYDISLYNEFLKFVAALPRCENIKATSTESKLIRRLVNDEIQPILKIDNASGIGWLVKKTLLSLIIDGLVVVEPLSGVNATYQIGYNSSSPAKQATSNMPKMFK... | autophagy exocytosis protein transport cell tip; cellular bud neck; cellular bud tip; cytosol; Golgi to plasma membrane transport vesicle; mating projection tip; transport vesicle guanyl-nucleotide exchange factor activity identical protein binding phosphatidylinositol-4-phosphate binding Saccharomyces cerevisiae 3D-s... |
cellular response to heat chaperone cofactor-dependent protein refolding protein refolding response to unfolded protein | blood microparticle; centriole; cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; nucleus; secretory granule lumen | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone enzyme binding heat shock protein binding protein folding chaperone ubiquitin protein ligase binding unfolded protein binding | Homo sapiens | 3D-structure ATP-binding Methylation Nucleotide-binding Reference proteome Stress response | MQAPRELAVG | MQAPRELAVGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNTVFDAKRLIGRKFADTTVQSDMKHWPFRVVSEGGKPKVRVCYRGEDKTFYPEEISSMVLSKMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGLDRRGAGERNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNHFMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSSSTQATLEIDSLFEGVDFYTSITRARFEELCSDLFRSTLEPVE... | cellular response to heat chaperone cofactor-dependent protein refolding protein refolding response to unfolded protein blood microparticle; centriole; cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; nucleus; secretory granule lumen ATP binding ATP hydrolysis activity ATP-... |
carbon utilization | chloroplast stroma | carbonate dehydratase activity zinc ion binding | Pisum sativum | 3D-structure Chloroplast Direct protein sequencing Lyase Plastid Transit peptide Zinc | MSTSSINGFS | MSTSSINGFSLSSLSPAKTSTKRTTLRPFVSASLNTSSSSSSSTFPSLIQDKPVFASSSPIITPVLREEMGKGYDEAIEELQKLLREKTELKATAAEKVEQITAQLGTTSSSDGIPKSEASERIKTGFLHFKKEKYDKNPALYGELAKGQSPPFMVFACSDSRVCPSHVLDFQPGEAFVVRNVANLVPPYDQAKYAGTGAAIEYAVLHLKVSNIVVIGHSACGGIKGLLSFPFDGTYSTDFIEEWVKIGLPAKAKVKAQHGDAPFAELCTHCEKEAVNASLGNLLTYPFVREGLVNKTLALKGGYYDFVKGSFELWGLEF... | carbon utilization chloroplast stroma carbonate dehydratase activity zinc ion binding Pisum sativum 3D-structure Chloroplast Direct protein sequencing Lyase Plastid Transit peptide Zinc MSTSSINGFS MSTSSINGFSLSSLSPAKTSTKRTTLRPFVSASLNTSSSSSSSTFPSLIQDKPVFASSSPIITPVLREEMGKGYDEAIEELQKLLREKTELKATAAEKVEQITAQLGTTSSSDGIPKSEASE... |
antimicrobial humoral immune response mediated by antimicrobial peptide erythrocyte differentiation maturation of SSU-rRNA maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) monocyte chemotaxis negative regulation of respiratory burst involved in inflammatory response Notch signali... | cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; nucleolus; postsynaptic density; ribosome; small ribosomal subunit; small-subunit processome; synapse | fibroblast growth factor binding identical protein binding protein kinase binding RNA binding structural constituent of ribosome translation initiation factor binding | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Methylation Nucleus Reference proteome Ribonucleoprotein Ribosomal protein | MPGVTVKDVN | MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH | antimicrobial humoral immune response mediated by antimicrobial peptide erythrocyte differentiation maturation of SSU-rRNA maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) monocyte chemotaxis negative regulation of respiratory burst involved in inflammatory response Notch signali... |
cytoplasmic translation maturation of LSU-rRNA | cytosol; cytosolic large ribosomal subunit | RNA binding structural constituent of ribosome | Saccharomyces cerevisiae | 3D-structure Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein | MAPGKKVAPA | MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQRQKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGKSKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIVKGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGNKAQAKMDKRAKNSDSA | cytoplasmic translation maturation of LSU-rRNA cytosol; cytosolic large ribosomal subunit RNA binding structural constituent of ribosome Saccharomyces cerevisiae 3D-structure Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein MAPGKKVAPA MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQP... |
actin filament organization cellular response to insulin stimulus cortical actin cytoskeleton organization endocytosis establishment or maintenance of cell polarity GTP metabolic process insulin receptor signaling pathway negative regulation of protein localization to plasma membrane positive regulation of filopodium a... | actin filament; extracellular exosome; Golgi-associated vesicle membrane; membrane raft; plasma membrane | GBD domain binding GTP binding GTPase activity profilin binding protein kinase binding | Homo sapiens | 3D-structure Cell membrane Cytoplasm GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MAHGPGALML | MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKRIGSRCINCCLIT | actin filament organization cellular response to insulin stimulus cortical actin cytoskeleton organization endocytosis establishment or maintenance of cell polarity GTP metabolic process insulin receptor signaling pathway negative regulation of protein localization to plasma membrane positive regulation of filopodium a... |
urea catabolic process | cytoplasm | nickel cation binding urease activity | Proteus mirabilis | Cytoplasm Hydrolase Metal-binding Nickel Virulence | MKTISRQAYA | MKTISRQAYADMFGPTTGDRLRLADTELFLEIEKDFTTYGEEVKFGGGKVIRDGMGQSQVVSAECVDVLITNAIILDYWGIVKADIGIKDGRIVGIGKAGNPDVQPNVDIVIGPGTEVVAGEGKIVTAGGIDTHIHFICPQQAQEGLVSGVTTFIGGGTGPVAGTNATTVTPGIWNMYRMLEAVDELPINVGLFGKGCVSQPEAIREQITAGAIGLKIHEDWGATPMAIHNCLNVADEMDVQVAIHSDTLNEGGFYEETVKAIAGRVIHVFHTEGAGGGHAPDVIKSVGEPNILPASTNPTMPYTINTVDEHLDMLMVCH... | urea catabolic process cytoplasm nickel cation binding urease activity Proteus mirabilis Cytoplasm Hydrolase Metal-binding Nickel Virulence MKTISRQAYA MKTISRQAYADMFGPTTGDRLRLADTELFLEIEKDFTTYGEEVKFGGGKVIRDGMGQSQVVSAECVDVLITNAIILDYWGIVKADIGIKDGRIVGIGKAGNPDVQPNVDIVIGPGTEVVAGEGKIVTAGGIDTHIHFICPQQAQEGLVSGVTTFIGGGTGPVAGTNATT... |
base-excision repair DNA unwinding involved in DNA replication negative regulation of cell population proliferation negative regulation of DNA-templated transcription nucleosome disassembly oncogene-induced cell senescence positive regulation of DNA-templated transcription positive regulation of transcription by RNA po... | cytosol; focal adhesion; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex; senescence-associated heterochromatin focus; transcription regulator complex | 5'-deoxyribose-5-phosphate lyase activity chromatin binding cis-regulatory region sequence-specific DNA binding DNA binding DNA binding, bending DNA-(apurinic or apyrimidinic site) endonuclease activity enzyme binding minor groove of adenine-thymine-rich DNA binding molecular adaptor activity molecular function activat... | Homo sapiens | 3D-structure Acetylation ADP-ribosylation Alternative splicing Chromosomal rearrangement Chromosome Direct protein sequencing DNA-binding Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Ubl conjugation | MSESSSKSSQ | MSESSSKSSQPLASKQEKDGTEKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRPRGRPKGSKNKGAAKTRKTTTTPGRKPRGRPKKLEKEEEEGISQESSEEEQ | base-excision repair DNA unwinding involved in DNA replication negative regulation of cell population proliferation negative regulation of DNA-templated transcription nucleosome disassembly oncogene-induced cell senescence positive regulation of DNA-templated transcription positive regulation of transcription by RNA po... |
microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response | extracellular region; host cell cytoplasm; host cell nucleus; T=4 icosahedral viral capsid | DNA binding RNA binding structural molecule activity | Hepatitis B virus genotype A2 subtype adw2 | Alternative initiation Disulfide bond Host nucleus Host-virus interaction Repeat Secreted Signal Viral immunoevasion | MQLFHLCLII | MQLFHLCLIISCTCPTVQASKLCLGWLWGMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGNNLEDPASRDLVVNYVNTNMGLKIRQLLWFRISYLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC | microtubule-dependent intracellular transport of viral material towards nucleus viral entry into host cell viral penetration into host nucleus virus-mediated perturbation of host defense response extracellular region; host cell cytoplasm; host cell nucleus; T=4 icosahedral viral capsid DNA binding RNA binding structura... |
actin cytoskeleton organization cellular response to calcium ion dendritic spine maintenance inositol metabolic process inositol phosphate biosynthetic process modification of postsynaptic actin cytoskeleton phosphatidylinositol phosphate biosynthetic process phosphorylation positive regulation of dendritic spine morph... | cytoplasm; cytoskeleton; dendritic spine; glutamatergic synapse; nucleus; postsynaptic actin cytoskeleton | ATP binding calmodulin binding calmodulin-dependent protein kinase activity inositol tetrakisphosphate kinase activity inositol-1,4,5-trisphosphate 3-kinase activity small GTPase binding | Rattus norvegicus | 3D-structure ATP-binding Calmodulin-binding Cytoplasm Cytoskeleton Direct protein sequencing Kinase Methylation Nucleotide-binding Phosphoprotein Reference proteome Transferase | MTLPGHPTGM | MTLPGHPTGMARPRGAGPCSPGLERAPRRSVGELRLLFEARCAAVAAAAAAGEPRARGAKRRGGQVPNGLPRAAPAPVIPQLTVTSEEDVAPASPGPPDREGNWLPAAGSHLQQPRRLSTSSLSSTGSSSLLEDSEDDLLSDSESRSRGNVQLETSEDVGQKSHWQKIRTMVNLPVMSPFKKRYSWVQLAGHTGSFKAAGTSGLILKRSSEPEHYCLVRLMADVLRGCVPAFHGVVERDGESYLQLQDLLDGFDGPCVLDCKMGVRTYLEEELTKARERPKLRKDMYKKMLAVDPEAPTEEEHAQRAVTKPRYMQWREGI... | actin cytoskeleton organization cellular response to calcium ion dendritic spine maintenance inositol metabolic process inositol phosphate biosynthetic process modification of postsynaptic actin cytoskeleton phosphatidylinositol phosphate biosynthetic process phosphorylation positive regulation of dendritic spine morph... |
chromatin remodeling chromosome segregation negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of sulfur metabolic process regulation of transcription by RNA polymerase II | Cbf1-Met4-Met28 complex; chromosome, centromeric region; kinetochore; mitochondrion; nucleus | centromeric DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription repressor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA poly... | Saccharomyces cerevisiae | 3D-structure Acetylation Centromere Chromosome Direct protein sequencing DNA-binding Mitochondrion Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MNSLANNNKL | MNSLANNNKLSTEDEEIHSARKRGYNEEQNYSEARKKQRDQGLLSQESNDGNIDSALLSEGATLKGTQSQYESGLTSNKDEKGSDDEDASVAEAAVAATVNYTDLIQGQEDSSDAHTSNQTNANGEHKDSLNGERAITPSNEGVKPNTSLEGMTSSPMESTQQSKNDMLIPLAEHDRGPEHQQDDEDNDDADIDLKKDISMQPGRRGRKPTTLATTDEWKKQRKDSHKEVERRRRENINTAINVLSDLLPVRESSKAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQLASANEKLQEELGNAYKEIEYMKRVL... | chromatin remodeling chromosome segregation negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of sulfur metabolic process regulation of transcription by RNA polymerase II Cbf1-Met4-Met28 complex; chromosome, centromeric region; kinetochore; mi... |
cell division karyogamy involved in conjugation with cellular fusion meiotic cell cycle microtubule bundle formation involved in mitotic spindle midzone assembly mitotic cell cycle mitotic sister chromatid cohesion nuclear migration involved in conjugation with cellular fusion protein transport along microtubule to mit... | chromosome; cytoplasmic microtubule; microtubule; nucleus; spindle pole; spindle pole body | ATP binding ATP hydrolysis activity isomerase activity microtubule binding minus-end-directed microtubule motor activity | Saccharomyces cerevisiae | 3D-structure ATP-binding Cell cycle Cell division Chromosome Coiled coil Cytoplasm Cytoskeleton Isomerase Karyogamy Microtubule Motor protein Nucleotide-binding Nucleus Reference proteome | MESLPRTPTK | MESLPRTPTKGRSTQHLSTPSPKNDILAMNGHKRRNTTTPPPKHTLLKPQRTDIHRHSLASQSRISMSPNRELLKNYKGTANLIYGNQKSNSGVTSFYKENVNELNRTQAILFEKKATLDLLKDELTETKEKINAVNLKFETLREEKIKIEQQLNLKNNELISIKEEFLSKKQFMNEGHEIHLKQLAASNKKELKQMENEYKTKIEKLKFMKIKQFENERASLLDKIEEVRNKITMNPSTLQEMLNDVEQKHMLEKEEWLTEYQSQWKKDIELNNKHMQEIESIKKEIENTLKPELAEKKKLLTEKRNAYEAIKVKVKEK... | cell division karyogamy involved in conjugation with cellular fusion meiotic cell cycle microtubule bundle formation involved in mitotic spindle midzone assembly mitotic cell cycle mitotic sister chromatid cohesion nuclear migration involved in conjugation with cellular fusion protein transport along microtubule to mit... |
chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger gastric acid secretion positive regulation of vasoconstriction | dendrite; plasma membrane; synapse | G protein-coupled serotonin receptor activity histamine receptor activity neurotransmitter receptor activity | Canis lupus familiaris | Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MISNGTGSSF | MISNGTGSSFCLDSPPCRITVSVVLTVLILITIAGNVVVCLAVGLNRRLRSLTNCFIVSLAITDLLLGLLVLPFSAFYQLSCRWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLITPVRVAVSLVLIWVISITLSFLSIHLGWNSRNETSSFNHTIPKCKVQVNLVYGLVDGLVTFYLPLLVMCITYYRIFKIARDQAKRIHHMGSWKAATIGEHKATVTLAAVMGAFIICWFPYFTVFVYRGLKGDDAINEAFEAVVLWLGYANSALNPILYATLNRDFRTAYQQLFRCRPASHNAQETSLRSN... | chemical synaptic transmission G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger gastric acid secretion positive regulation of vasoconstriction dendrite; plasma membrane; synapse G protein-coupled serotonin receptor activity histamine receptor activity neurotransmitter receptor... |
mRNA splicing, via spliceosome negative regulation of mRNA splicing, via spliceosome oogenesis regulation of alternative mRNA splicing, via spliceosome regulation of RNA splicing spermatogenesis | catalytic step 2 spliceosome; nuclear speck; nucleus; precatalytic spliceosome; spliceosomal complex; U1 snRNP; U2-type prespliceosome | mRNA binding RNA binding U1 snRNA binding | Drosophila melanogaster | 3D-structure mRNA processing Nucleus Reference proteome Ribonucleoprotein RNA-binding | MTQYLPPNLL | MTQYLPPNLLALFAAREPIPFMPPVDKLPHEKKSRGYLGVAKFMADFEDPKDTPLPKTVETRQERLERRRREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESKLRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLVDVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDREGPGRGGGSNGLDARPGRGFGAERRRSRSRERRDRERDRGRGAVASNGRSRSRSRERRKRRAGSRERYDEFDRRDRRDRERERDRDRER... | mRNA splicing, via spliceosome negative regulation of mRNA splicing, via spliceosome oogenesis regulation of alternative mRNA splicing, via spliceosome regulation of RNA splicing spermatogenesis catalytic step 2 spliceosome; nuclear speck; nucleus; precatalytic spliceosome; spliceosomal complex; U1 snRNP; U2-type presp... |
mRNA splicing, via spliceosome spliceosomal snRNP assembly | catalytic step 2 spliceosome; cytoplasm; cytosol; histone pre-mRNA 3'end processing complex; methylosome; nucleoplasm; nucleus; SMN-Sm protein complex; spliceosomal complex; telomerase holoenzyme complex; U1 snRNP; U12-type spliceosomal complex; U2 snRNP; U2-type catalytic step 2 spliceosome; U2-type precatalytic splic... | histone pre-mRNA DCP binding RNA binding telomerase RNA binding U1 snRNP binding U2 snRNP binding | Rattus norvegicus | Cytoplasm Methylation mRNA processing mRNA splicing Nucleus Reference proteome Repeat Ribonucleoprotein RNA-binding Spliceosome | MTVGKSSKML | MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGLL | mRNA splicing, via spliceosome spliceosomal snRNP assembly catalytic step 2 spliceosome; cytoplasm; cytosol; histone pre-mRNA 3'end processing complex; methylosome; nucleoplasm; nucleus; SMN-Sm protein complex; spliceosomal complex; telomerase holoenzyme complex; U1 snRNP; U12-type spliceosomal complex; U2 snRNP; U2-ty... |
calcium ion homeostasis negative regulation of coagulation | calcium channel complex; cytoplasm; sarcolemma; vesicle | calcium channel activity calcium ion binding calcium-dependent phospholipid binding | Gallus gallus | 3D-structure Annexin Calcium Calcium/phospholipid-binding Direct protein sequencing Reference proteome Repeat | MAKYTRGTVT | MAKYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQKDTSGDYRKALLLLCGGDD... | calcium ion homeostasis negative regulation of coagulation calcium channel complex; cytoplasm; sarcolemma; vesicle calcium channel activity calcium ion binding calcium-dependent phospholipid binding Gallus gallus 3D-structure Annexin Calcium Calcium/phospholipid-binding Direct protein sequencing Reference proteome Repe... |
chaperone cofactor-dependent protein refolding male meiosis I male meiotic nuclear division negative regulation of inclusion body assembly positive regulation of ATP-dependent activity positive regulation of ATPase-coupled calcium transmembrane transporter activity positive regulation of G2/M transition of mitotic cell... | CatSper complex; cell surface; cytoplasm; cytosol; male germ cell nucleus; meiotic spindle; mitochondrion; myelin sheath; nucleoplasm; nucleus; plasma membrane; synaptonemal complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone disordered domain specific binding enzyme binding glycolipid binding heat shock protein binding protein folding chaperone protein-folding chaperone binding tau protein binding unfolded protein binding | Mus musculus | ATP-binding Chaperone Cytoplasm Cytoskeleton Differentiation Methylation Nucleotide-binding Phosphoprotein Reference proteome Spermatogenesis Stress response | MSARGPAIGI | MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPV... | chaperone cofactor-dependent protein refolding male meiosis I male meiotic nuclear division negative regulation of inclusion body assembly positive regulation of ATP-dependent activity positive regulation of ATPase-coupled calcium transmembrane transporter activity positive regulation of G2/M transition of mitotic cell... |
fucose metabolic process glycoside catabolic process lipid metabolic process | lysosome | alpha-L-fucosidase activity carbohydrate binding fucosidase activity | Rattus norvegicus | Direct protein sequencing Glycoprotein Glycosidase Hydrolase Lipid metabolism Lysosome Reference proteome Signal | MWDLKSEWWA | MWDLKSEWWAVGFGLLLLLAASAQAGGLAPHHYTPDWPSLDSRPLPRWFDEAKFGLFVHWGVYSVPAWGSEWFWWHWQGEQSSAYVRFMKENYPPGFSYADFAPQFTARFFHPEEWADLFQAAGAKYVVLTAKHHEGFTNWPSAVSWNWNSKDVGPHRDLVGELGAAVRKRNIRYGLYHSLFEWFHPLYLLDKKNGLKTQHFVSTKTMPELYDLVNRYKPDLIWSDGEWECPDSYWNSTEFLAWLYNESPVKDQVVVNDRWGQNCSCRHGGYYNCEDKYRPHSLPDHKWEMCTSVDKASWGYRRDMSMSTIVDENEIIEE... | fucose metabolic process glycoside catabolic process lipid metabolic process lysosome alpha-L-fucosidase activity carbohydrate binding fucosidase activity Rattus norvegicus Direct protein sequencing Glycoprotein Glycosidase Hydrolase Lipid metabolism Lysosome Reference proteome Signal MWDLKSEWWA MWDLKSEWWAVGFGLLLLLAASA... |
carbohydrate metabolic process fructose 6-phosphate metabolic process glutamine metabolic process protein N-linked glycosylation UDP-N-acetylglucosamine biosynthetic process UDP-N-acetylglucosamine metabolic process | cytosol | carbohydrate derivative binding glutamine-fructose-6-phosphate transaminase (isomerizing) activity | Escherichia coli | 3D-structure Aminotransferase Cytoplasm Direct protein sequencing Glutamine amidotransferase Reference proteome Repeat Transferase | MCGIVGAIAQ | MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTVIMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAG... | carbohydrate metabolic process fructose 6-phosphate metabolic process glutamine metabolic process protein N-linked glycosylation UDP-N-acetylglucosamine biosynthetic process UDP-N-acetylglucosamine metabolic process cytosol carbohydrate derivative binding glutamine-fructose-6-phosphate transaminase (isomerizing) activi... |
2-oxoglutarate metabolic process aspartate biosynthetic process aspartate catabolic process aspartate metabolic process cellular response to insulin stimulus fatty acid homeostasis gluconeogenesis glutamate catabolic process to 2-oxoglutarate glutamate catabolic process to aspartate glutamate metabolic process glycerol... | cytoplasm; cytosol; extracellular exosome; nucleus | L-aspartate:2-oxoglutarate aminotransferase activity L-cysteine transaminase activity phosphatidylserine decarboxylase activity pyridoxal phosphate binding | Homo sapiens | 3D-structure Alternative splicing Amino-acid biosynthesis Aminotransferase Cytoplasm Direct protein sequencing Phosphoprotein Pyridoxal phosphate Reference proteome Transferase | MAPPSVFAEV | MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEW... | 2-oxoglutarate metabolic process aspartate biosynthetic process aspartate catabolic process aspartate metabolic process cellular response to insulin stimulus fatty acid homeostasis gluconeogenesis glutamate catabolic process to 2-oxoglutarate glutamate catabolic process to aspartate glutamate metabolic process glycerol... |
bile acid biosynthetic process C21-steroid hormone biosynthetic process calcitriol biosynthetic process from calciol cholesterol catabolic process | mitochondrial inner membrane | 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity cholestanetetraol 26-dehydrogenase activity cholestanetriol 26-monooxygenase activity cholesterol 26-hydroxylase activity cholesterol 7-alpha-monooxygenase activity cholesterol monooxygenase (side-chain-cleaving) activity heme binding Hsp70 p... | Oryctolagus cuniculus | Acetylation Cholesterol metabolism Direct protein sequencing Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroid biosynthesis Steroid metabolism Sterol metabolism Transit peptide | MAALGCARLR | MAALGCARLRWALLGPRVAGCGLCPQGARAKAAIPTALPADEAAQAPGAGPGDRRRRRSLEELPRLGQLRFFYQAFVQGYLLHLHKLQVLNKARYGPMWVSYLGPQLFVNLASAPLVETVMRQEGKYPVRNDMQLWKEHRDHQDLAYGVFTTDGHDWYQLRQALNQRLLKPAEAALYTDALNEVIDSFVVRLDQLRAESASGDQVPDMADLLYHFALEAICYILFEKRIGCLEASIPKDTENFIRSVGLMFQNSVYVTFLPKWTRPLLPFWKRYLDGWDTIFSFGKNLIDQKLQEVVAQLQSAGSDGVQVSGYLHSLLTS... | bile acid biosynthetic process C21-steroid hormone biosynthetic process calcitriol biosynthetic process from calciol cholesterol catabolic process mitochondrial inner membrane 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity cholestanetetraol 26-dehydrogenase activity cholestanetriol 26-mon... |
bile acid biosynthetic process C21-steroid hormone biosynthetic process calcitriol biosynthetic process from calciol cholesterol catabolic process cholesterol metabolic process steroid catabolic process | mitochondrial inner membrane; mitochondrion | 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity cholestanetetraol 26-dehydrogenase activity cholestanetriol 26-monooxygenase activity cholesterol 26-hydroxylase activity cholesterol 7-alpha-monooxygenase activity cholesterol monooxygenase (side-chain-cleaving) activity heme binding Hsp70 p... | Rattus norvegicus | Acetylation Cholesterol metabolism Direct protein sequencing Heme Iron Lipid biosynthesis Lipid metabolism Membrane Metal-binding Mitochondrion Mitochondrion inner membrane Monooxygenase Oxidoreductase Reference proteome Steroid biosynthesis Steroid metabolism Sterol metabolism Transit peptide | MAVLSRMRLR | MAVLSRMRLRWALLDTRVMGHGLCPQGARAKAAIPAALRDHESTEGPGTGQDRPRLRSLAELPGPGTLRFLFQLFLRGYVLHLHELQALNKAKYGPMWTTTFGTRTNVNLASAPLLEQVMRQEGKYPIRDSMEQWKEHRDHKGLSYGIFITQGQQWYHLRHSLNQRMLKPAEAALYTDALNEVISDFIARLDQVRTESASGDQVPDVAHLLYHLALEAICYILFEKRVGCLEPSIPEDTATFIRSVGLMFKNSVYVTFLPKWSRPLLPFWKRYMNNWDNIFSFGEKMIHQKVQEIEAQLQAAGPDGVQVSGYLHFLLTKE... | bile acid biosynthetic process C21-steroid hormone biosynthetic process calcitriol biosynthetic process from calciol cholesterol catabolic process cholesterol metabolic process steroid catabolic process mitochondrial inner membrane; mitochondrion 3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase acti... |
cellular response to interferon-alpha cellular response to interferon-beta cellular response to virus positive regulation of cellular respiration receptor signaling pathway via JAK-STAT response to lipopolysaccharide response to virus type I interferon-mediated signaling pathway | late endosome; lysosome; plasma membrane | cytokine binding JAK pathway signal transduction adaptor activity type I interferon binding type I interferon receptor activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Disease variant Disulfide bond Endosome Glycoprotein Isopeptide bond Lipoprotein Lysosome Membrane Palmitate Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix Ubl conjugation | MMVVLLGATT | MMVVLLGATTLVLVAVAPWVLSAAAGGKNLKSPQKVEVDIIDDNFILRWNRSDESVGNVTFSFDYQKTGMDNWIKLSGCQNITSTKCNFSSLKLNVYEEIKLRIRAEKENTSSWYEVDSFTPFRKAQIGPPEVHLEAEDKAIVIHISPGTKDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTYCLKVKAALLTSWKIGVYSPVHCIKTTVENELPPPENIEVSVQNQNYVLKWDYTYANMTFQVQWLHAFLKRNPGNHLYKWKQIPDCENVKTTQCVFPQNVFQKGIYLLRVQASDGNNTSFWSE... | cellular response to interferon-alpha cellular response to interferon-beta cellular response to virus positive regulation of cellular respiration receptor signaling pathway via JAK-STAT response to lipopolysaccharide response to virus type I interferon-mediated signaling pathway late endosome; lysosome; plasma membrane... |
canonical glycolysis cellular response to interleukin-7 gluconeogenesis glyceraldehyde-3-phosphate biosynthetic process glycolytic process in utero embryonic development negative regulation of cell growth negative regulation of DNA-templated transcription negative regulation of hypoxia-induced intrinsic apoptotic signa... | cell cortex; cell surface; cytoplasm; cytosol; growth cone; membrane; membrane raft; myelin sheath; nuclear outer membrane; phosphopyruvate hydratase complex; plasma membrane; synaptic membrane | DNA-binding transcription repressor activity, RNA polymerase II-specific enzyme binding GTPase binding heat shock protein binding identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein homodimerization activity protein-containing complex binding RNA binding RNA polymerase II transcri... | Mus musculus | Acetylation Cell membrane Cytoplasm Direct protein sequencing Glycolysis Hydroxylation Isopeptide bond Lyase Magnesium Membrane Metal-binding Phosphoprotein Reference proteome Ubl conjugation | MSILRIHARE | MSILRIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSQAVEHINKTIAPALVSKKVNVVEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIAKAGYTDQVVIGMDVAASEFYRSGKYDLDFKSPDDPSRYITPDQLADLYKSFVQNYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDL... | canonical glycolysis cellular response to interleukin-7 gluconeogenesis glyceraldehyde-3-phosphate biosynthetic process glycolytic process in utero embryonic development negative regulation of cell growth negative regulation of DNA-templated transcription negative regulation of hypoxia-induced intrinsic apoptotic signa... |
canonical glycolysis gluconeogenesis glycolytic process | cell cortex; cell surface; cytoplasm; cytosol; growth cone; membrane; membrane raft; myelin sheath; neuronal cell body; perikaryon; phosphopyruvate hydratase complex; photoreceptor inner segment; plasma membrane; synaptic membrane | enzyme binding identical protein binding magnesium ion binding phosphopyruvate hydratase activity protein-containing complex binding | Mus musculus | Acetylation Cell membrane Cytoplasm Direct protein sequencing Glycolysis Hydroxylation Isopeptide bond Lyase Magnesium Membrane Metal-binding Phosphoprotein Reference proteome Ubl conjugation | MSIEKIWARE | MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSRIAPALISSGISVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERDLPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSPADPSRYITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDL... | canonical glycolysis gluconeogenesis glycolytic process cell cortex; cell surface; cytoplasm; cytosol; growth cone; membrane; membrane raft; myelin sheath; neuronal cell body; perikaryon; phosphopyruvate hydratase complex; photoreceptor inner segment; plasma membrane; synaptic membrane enzyme binding identical protein ... |
actin filament bundle organization anterograde axonal transport of mitochondrion anterograde dendritic transport anterograde dendritic transport of neurotransmitter receptor complex axo-dendritic transport axon guidance axonogenesis centrosome separation dendrite morphogenesis dorsal appendage formation eye photorecept... | actin cap; axon cytoplasm; cytoplasm; dendrite cytoplasm; kinesin complex; microtubule; microtubule plus-end | ATP binding ATP hydrolysis activity cytoskeletal motor activity microtubule binding microtubule motor activity plus-end-directed microtubule motor activity tropomyosin binding | Drosophila melanogaster | 3D-structure ATP-binding Coiled coil Cytoplasm Cytoskeleton Microtubule Motor protein Nucleotide-binding Reference proteome | MSAEREIPAE | MSAEREIPAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESET... | actin filament bundle organization anterograde axonal transport of mitochondrion anterograde dendritic transport anterograde dendritic transport of neurotransmitter receptor complex axo-dendritic transport axon guidance axonogenesis centrosome separation dendrite morphogenesis dorsal appendage formation eye photorecept... |
defense response to Gram-negative bacterium innate immune response lipopolysaccharide-mediated signaling pathway negative regulation of interleukin-6 production negative regulation of interleukin-8 production negative regulation of macrophage activation negative regulation of tumor necrosis factor production | azurophil granule lumen; extracellular exosome; extracellular region; extracellular space; membrane; specific granule lumen | lipopolysaccharide binding | Homo sapiens | 3D-structure Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Glycoprotein Immunity Innate immunity Membrane Reference proteome Secreted Signal | MRENMARGPC | MRENMARGPCNAPRWASLMVLVAIGTAVTAAVNPGVVVRISQKGLDYASQQGTAALQKELKRIKIPDYSDSFKIKHLGKGHYSFYSMDIREFQLPSSQISMVPNVGLKFSISNANIKISGKWKAQKRFLKMSGNFDLSIEGMSISADLKLGSNPTSGKPTITCSSCSSHINSVHVHISKSKVGWLIQLFHKKIESALRNKMNSQVCEKVTNSVSSELQPYFQTLPVMTKIDSVAGINYGLVAPPATTAETLDVQMKGEFYSENHHNPPPFAPPVMEFPAAHDRMVYLGLSDYFFNTAGLVYQEAGVLKMTLRDDMIPKES... | defense response to Gram-negative bacterium innate immune response lipopolysaccharide-mediated signaling pathway negative regulation of interleukin-6 production negative regulation of interleukin-8 production negative regulation of macrophage activation negative regulation of tumor necrosis factor production azurophil ... |
G-quadruplex DNA formation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay regulation of telomere maintenance via telomerase telomere maintenance telomere maintenance via telomerase | chromosome, telomeric region; nucleolus; nucleus; telomerase holoenzyme complex | RNA binding single-stranded DNA binding telomerase RNA binding telomeric DNA binding | Saccharomyces cerevisiae | Chromosome DNA-binding Nucleus Reference proteome Telomere | MDNEEVNEEC | MDNEEVNEECMRLFFKNARAHLDKHLTSRLTCDENAYITFRCFLDGIHRKSTRFLEELLLKQENMYHNNNYERINDSVIPLVLKLLWLQIHEPTLQWFEHWFHDIMRLSNRRKFRVFRIFQKKMIQFFKITHRYYYDIIEHLCAKYDMNSVISNALFAKLNLMQYTDGLSTHEKIILNTSNPLTFSIVISLQRCVINLGSTHFYKTLLNKPSNKPKSVEGFEKSIRYLNIASLYLPAVGDTYFQRAKIYLITGKFSLYFFELVRGALVRIPSKCALNNLKDFILTPDFPERRRLMKKLAILVSKDLKGEKSFFEGQIVLQ... | G-quadruplex DNA formation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay regulation of telomere maintenance via telomerase telomere maintenance telomere maintenance via telomerase chromosome, telomeric region; nucleolus; nucleus; telomerase holoenzyme complex RNA binding single-stranded DNA bindin... |
cell differentiation male germ-line sex determination male sex determination male somatic sex determination masculinization of hermaphroditic germ-line proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination regulation of gene expression regulation of germ cell proliferation sex determi... | Cul2-RING ubiquitin ligase complex; cytoplasm; protein serine/threonine phosphatase complex; protein-containing complex; ubiquitin ligase complex | protein phosphatase binding | Caenorhabditis elegans | Alternative splicing ANK repeat Cytoplasm Developmental protein Differentiation Phosphoprotein Reference proteome Repeat Sexual differentiation TPR repeat Ubl conjugation pathway | MTPNGHHFRT | MTPNGHHFRTVIYNAAAVGNLQRIKVFTINSRNDRQWIIDCFNSDQDGRYPLVIAARNGHANVVEYLLEIGADPSVRGVVEFDNENIQGTPPLWAASAAGHIEIVKLLIEKANADVNQATNTRSTPLRGACYDGHLDIVKYLLEKGADPHIPNRHGHTCLMIASYRNKVGIVEELLKTGIDVNKKTERGNTALHDAAESGNVEVVKILLKHGSVLMKDIQGVDPLMGAALSGFLDVLNVLADQMPSGIHKRDALKLLGSTLLDKKMDAMSAMNCWKQSMEVPLHADDLRLVREMETFFEPQEVYEYQREAQNIAQVELLD... | cell differentiation male germ-line sex determination male sex determination male somatic sex determination masculinization of hermaphroditic germ-line proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination regulation of gene expression regulation of germ cell proliferation sex determi... |
3'-UTR-mediated mRNA stabilization gene expression IRES-dependent viral translational initiation mRNA processing negative regulation of mRNA splicing, via spliceosome negative regulation of muscle cell differentiation negative regulation of neuron differentiation negative regulation of RNA splicing neurogenesis nuclear... | neuron projection terminus; nucleus | DNA binding mRNA binding pre-mRNA binding regulatory region RNA binding RNA binding sequence-specific DNA binding single-stranded DNA binding single-stranded DNA endodeoxyribonuclease activity | Mus musculus | Acetylation Activator Alternative splicing Direct protein sequencing Isopeptide bond mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Repressor RNA-binding Ubl conjugation | MDGIVPDIAV | MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSSSASAANGNDSKKFKGDNRSAGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQ... | 3'-UTR-mediated mRNA stabilization gene expression IRES-dependent viral translational initiation mRNA processing negative regulation of mRNA splicing, via spliceosome negative regulation of muscle cell differentiation negative regulation of neuron differentiation negative regulation of RNA splicing neurogenesis nuclear... |
glucose metabolic process glycolytic process innate immune response microtubule cytoskeleton organization neuron apoptotic process peptidyl-cysteine S-trans-nitrosylation positive regulation of canonical NF-kappaB signal transduction positive regulation of type I interferon production protein stabilization regulation o... | cytoplasm; cytosol; GAIT complex; microtubule cytoskeleton; nucleus | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity microtubule binding NAD binding NADP binding peptidyl-cysteine S-nitrosylase activity | Cricetulus griseus | Acetylation ADP-ribosylation Apoptosis Cytoplasm Cytoskeleton Glycolysis Immunity Innate immunity Isopeptide bond Methylation NAD Nucleus Oxidoreductase Phosphoprotein S-nitrosylation Transferase Translation regulation Ubl conjugation | MVKVGVNGFG | MVKVGVNGFGRIGRLVTRAAFTSGKVEVVAINDPFIDLNYMVYMFQYDSTHGKFKGTVKAENGKLVINGKAITIFQERDPANIKWGDAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNQDKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYEDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSDSHSSTFDAGAGIALNDNFVKLISWYDNEFGYSN... | glucose metabolic process glycolytic process innate immune response microtubule cytoskeleton organization neuron apoptotic process peptidyl-cysteine S-trans-nitrosylation positive regulation of canonical NF-kappaB signal transduction positive regulation of type I interferon production protein stabilization regulation o... |
cholesterol biosynthetic process isopentenyl diphosphate biosynthetic process, mevalonate pathway isoprenoid biosynthetic process isoprenoid metabolic process negative regulation of inflammatory response negative regulation of translation phosphorylation regulation of cholesterol biosynthetic process sterol metabolic p... | cytoplasm; cytosol; peroxisome | ATP binding identical protein binding magnesium ion binding mevalonate kinase activity mRNA binding sequence-specific mRNA binding | Rattus norvegicus | 3D-structure ATP-binding Cholesterol biosynthesis Cholesterol metabolism Cytoplasm Direct protein sequencing Kinase Lipid biosynthesis Lipid metabolism Magnesium Metal-binding Nucleotide-binding Peroxisome Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transferase | MLSEVLLVSA | MLSEVLLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPRSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELMDMNQHHLNALGVGHASLDQLCQ... | cholesterol biosynthetic process isopentenyl diphosphate biosynthetic process, mevalonate pathway isoprenoid biosynthetic process isoprenoid metabolic process negative regulation of inflammatory response negative regulation of translation phosphorylation regulation of cholesterol biosynthetic process sterol metabolic p... |
fungal-type cell wall organization | extracellular region; fungal-type cell wall; fungal-type vacuole; plasma membrane; side of membrane | structural constituent of cell wall | Saccharomyces cerevisiae | Cell membrane Cell wall Cell wall biogenesis/degradation Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Repeat Secreted Signal | MMRRTLLHSF | MMRRTLLHSFATLLLSLSLWSAAVMAAVTTQVTVVTNVAGALVTETTIWDPATAAAAATTTAQTGFFTTVFTTTNDVGTTVTLTQTVNRATMLPTTTTSTSSTGKTTTTVPTATSSLSSGLYLSTVTTTNDLGTTVTLTQTFTHSSTSATSSASSSVSSSVSSSGSSSSVKTTTSTGSAVAETGTRPDPSTDFTEPPVSAVTSLSIDSYITITEGTTSTYTTTRAPTSMWVTVVRQGNTITVQTTFVQRFSSQYVTVASPSVGSIGMGTLTGTVGVIKSAIKKTVSHNEAQHLGMSSFTSILGGLLTVLIWFL | fungal-type cell wall organization extracellular region; fungal-type cell wall; fungal-type vacuole; plasma membrane; side of membrane structural constituent of cell wall Saccharomyces cerevisiae Cell membrane Cell wall Cell wall biogenesis/degradation Glycoprotein GPI-anchor Lipoprotein Membrane Reference proteome Re... |
cellular response to calcium ion decidualization embryonic process involved in female pregnancy integrated stress response signaling labyrinthine layer blood vessel development osteoblast differentiation osteoblast proliferation osteoclast differentiation osteoclast proliferation positive regulation of cell differentia... | chromatin; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex; transcription factor AP-1 complex; transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Acetylation DNA-binding Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MCTKMEQPFY | MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGPEGGGGGSYFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGATGGPPAGPGGVYAGPEPPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQ... | cellular response to calcium ion decidualization embryonic process involved in female pregnancy integrated stress response signaling labyrinthine layer blood vessel development osteoblast differentiation osteoblast proliferation osteoclast differentiation osteoclast proliferation positive regulation of cell differentia... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Simian immunodeficiency virus | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Mem... | MKVMEKKKRD | MKVMEKKKRDWNSLSIITIITIILLTPCLTSELWVTVYYGVPVWHDADPVLFCASDAKAHSTEAHNIWATQACVPTDPSPQEVFLPNVIESFNMWKNNMVDQMHEDIISLWDQSLKPCVKLTPLCVTLQCSKANFSQAKNLTNQTSSPPLEMKNCSFNVTTELRDKKKQVYSLFYVEDVVNLGNENNTYRIINCNTTAITQACPKTSFEPIPIHYCAPAGFAILKCNDKDFSGKGKCTNVSTVHCTHGIKPVVTTQLLINGSLAEGNITVRVENKSKNTDVWIVQLVEAVSLNCHRPGNNTRGEVQIGPGMTFYNIENVV... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
viral budding via host ESCRT complex | host cell cytoplasm; host cell nucleus; host cell plasma membrane; membrane; viral nucleocapsid | RNA binding structural molecule activity zinc ion binding | Simian immunodeficiency virus | Capsid protein Host cell membrane Host cytoplasm Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from host cell Virion Zinc ... | MGARASVLTG | MGARASVLTGGKLDRWEKVRLRPGGRKRYMMKHLVWASRELERFACDPGLMESKEGCTKLLQQLEPALKTGSEGLRSLFNTLAVLWCIHSDITVEDTQKALEQLKRHHGEQQSKTESNSGSREGGASQGASASAGISGNYPLVQNAQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGALPQDVNTMLNAVGGHQGAMQVLKEVINEEAAEWDRLHPTHAGPIAPGQLREPRGSDIAGTTSTLQEQIGWTTANPPIPVGDVYRRWVILGLNKVVRMYCPVSILDIRQGPKEPFRDYVDRFYKTLRAEQASQE... | viral budding via host ESCRT complex host cell cytoplasm; host cell nucleus; host cell plasma membrane; membrane; viral nucleocapsid RNA binding structural molecule activity zinc ion binding Simian immunodeficiency virus Capsid protein Host cell membrane Host cytoplasm Host membrane Host nucleus Host-virus interactio... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Simian immunodeficiency virus | Acetylation Activator AIDS Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 activity by virus Pho... | MDPIDPDLEP | MDPIDPDLEPWKHPGSQPRTVCNNCYCKACCYHCIYCFTKKGLGISYGRKKRTTRRRTAPAGSKNNQDSIPKQPLSQSRGNKEGSEKSTKEVASKTEADQ | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
dopamine biosynthetic process from tyrosine heart development hyaloid vascular plexus regression response to ethanol response to hypoxia | axon; cytoplasm; nucleus; perikaryon; perinuclear region of cytoplasm; synaptic vesicle | iron ion binding tyrosine 3-monooxygenase activity | Bos taurus | Catecholamine biosynthesis Cell projection Cytoplasm Cytoplasmic vesicle Direct protein sequencing Iron Metal-binding Monooxygenase Neurotransmitter biosynthesis Nucleus Oxidoreductase Phosphoprotein Reference proteome Synapse | MPTPNAASPQ | MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFVGRRQSLIQDARKEREKAEAAASSSESAEAAAWLERDGEAVLTLLFALPPTRPPALTRAIKVFETFEAHLHHLETRPAQPLRAGSPPLECFVRCEVPGPVVPALLSALRRVAEDVRAAGESKVLWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYSTLRGLYPTHACREHLEAFELLERFCGYREDRIPQLEDVSRFLKERTGFQLRPAAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEP... | dopamine biosynthetic process from tyrosine heart development hyaloid vascular plexus regression response to ethanol response to hypoxia axon; cytoplasm; nucleus; perikaryon; perinuclear region of cytoplasm; synaptic vesicle iron ion binding tyrosine 3-monooxygenase activity Bos taurus Catecholamine biosynthesis Cell p... |
response to antibiotic translation | small ribosomal subunit | rRNA binding structural constituent of ribosome tRNA binding | Thermus thermophilus | 3D-structure Antibiotic resistance Direct protein sequencing Methylation Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding tRNA-binding | MPTINQLVRK | MPTINQLVRKGREKVRKKSKVPALKGAPFRRGVCTVVRTVTPKKPNSALRKVAKVRLTSGYEVTAYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGVYDAAGVKDRKKSRSKYGTKKPKEAAKTAAKK | response to antibiotic translation small ribosomal subunit rRNA binding structural constituent of ribosome tRNA binding Thermus thermophilus3D-structure Antibiotic resistance Direct protein sequencing Methylation Ribonucleoprotein Ribosomal protein RNA-binding rRNA-binding tRNA-binding MPTINQLVRK MPTINQLVRKGREKVRKKSKVP... |
chromosome organization viral DNA genome packaging viral genome packaging viral procapsid maturation | viral terminase, large subunit | ATP binding ATP hydrolysis activity DNA nuclease activity endonuclease activity metal ion binding nuclease activity | Enterobacteria phage T4 | 3D-structure Alternative initiation ATP-binding Endonuclease Hydrolase Magnesium Metal-binding Nuclease Nucleotide-binding Reference proteome Viral genome packaging Viral release from host cell | MEQPINVLND | MEQPINVLNDFHPLNEAGKILIKHPSLAERKDEDGIHWIKSQWDGKWYPEKFSDYLRLHKIVKIPNNSDKPELFQTYKDKNNKRSRYMGLPNLKRANIKTQWTREMVEEWKKCRDDIVYFAETYCAITHIDYGVIKVQLRDYQRDMLKIMSSKRMTVCNLSRQLGKTTVVAIFLAHFVCFNKDKAVGILAHKGSMSAEVLDRTKQAIELLPDFLQPGIVEWNKGSIELDNGSSIGAYASSPDAVRGNSFAMIYIDECAFIPNFHDSWLAIQPVISSGRRSKIIITTTPNGLNHFYDIWTAAVEGKSGFEPYTAIWNSVKE... | chromosome organization viral DNA genome packaging viral genome packaging viral procapsid maturation viral terminase, large subunit ATP binding ATP hydrolysis activity DNA nuclease activity endonuclease activity metal ion binding nuclease activity Enterobacteria phage T4 3D-structure Alternative initiation ATP-binding ... |
fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell | host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Lassa virus | Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Transmembrane Transmembrane helix Viral attac... | MGQIVTFFQE | MGQIVTFFQEVPHVIEEVMNIVLIALSILAILKGLYNVATCGLIGLVTFLLLSGRSCSLIYKGTYELQTLELNMETLNMTMPLSCTKNNSHHYIRVGNETGLELTLTNTSILNHKFCNLSDAHKRNLYDHSLMSIISTFHLSIPNFNQYEAMSCDFNGGKITVQYNLSHSFAVDAAGHCGTLANGVLQTFMRMAWGGSYIALDSGRGNWDCIMTSYQYLIIQNTTWDDHCQFSRPSPIGYLGLLSQRTRDIYISRRLLGTFTWTLSDSEGNETPGGYCLTRWMLIEAELKCFGNTAVAKCNEKHDEEFCDMLRLFDFNKQ... | fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Lassa virus Disulfide bond F... |
determination of adult lifespan heart morphogenesis hydrogen peroxide catabolic process intestinal stem cell homeostasis paracrine signaling reactive oxygen species metabolic process regulation of hemocyte proliferation regulation of synaptic plasticity response to endoplasmic reticulum stress response to hydrogen pero... | cytoplasm; mitochondrion; peroxisome | catalase activity heme binding metal ion binding | Drosophila melanogaster | Direct protein sequencing Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Peroxisome Reference proteome | MAGRDAASNQ | MAGRDAASNQLIDYKNSQTVSPGAITTGNGAPIGIKDASQTVGPRGPILLQDVNFLDEMSHFDRERIPERVVHAKGAGAFGYFEVTHDITQYCAAKIFDKVKKRTPLAVRFSTVGGESGSADTARDPRGFAVKFYTEDGVWDLVGNNTPVFFIRDPILFPSFIHTQKRNPQTHLKDPDMFWDFLTLRPESAHQVCILFSDRGTPDGYCHMNGYGSHTFKLINAKGEPIYAKFHFKTDQGIKNLDVKTADQLASTDPDYSIRDLYNRIKTCKFPSWTMYIQVMTYEQAKKFKYNPFDVTKVWSQKEYPLIPVGKMVLDRNP... | determination of adult lifespan heart morphogenesis hydrogen peroxide catabolic process intestinal stem cell homeostasis paracrine signaling reactive oxygen species metabolic process regulation of hemocyte proliferation regulation of synaptic plasticity response to endoplasmic reticulum stress response to hydrogen pero... |
angiogenesis blood vessel remodeling negative regulation of cold-induced thermogenesis osteoclast proliferation positive regulation of nitric-oxide synthase activity positive regulation of urine volume regulation of blood pressure regulation of osteoblast proliferation response to ischemia signal transduction skeletal ... | extracellular exosome; plasma membrane; protein-containing complex | chloride ion binding G protein-coupled peptide receptor activity hormone binding natriuretic peptide receptor activity peptide binding peptide hormone binding protein homodimerization activity | Homo sapiens | 3D-structure Alternative splicing Cell membrane Chloride Direct protein sequencing Disease variant Disulfide bond Glycoprotein Membrane Receptor Reference proteome Signal Transmembrane Transmembrane helix | MPSLLVLTFS | MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQ... | angiogenesis blood vessel remodeling negative regulation of cold-induced thermogenesis osteoclast proliferation positive regulation of nitric-oxide synthase activity positive regulation of urine volume regulation of blood pressure regulation of osteoblast proliferation response to ischemia signal transduction skeletal ... |
proteolysis | extracellular region | metal ion binding metalloendopeptidase activity toxin activity | Echis carinatus sochureki | 3D-structure Cell adhesion impairing toxin Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Platelet aggregation inhibiting toxin Protease Pyrrolidone carboxylic acid Secreted Toxin Zinc | IGIAYNRGMC | IGIAYNRGMCDPKKSVGTVMDHSTEHLSVAVAMAHEMGHNLGMDHDGNQCNCGGAGCVMSEELIESRSYKFSDCSKNQYQNYLTIYKPQCILNQPLRTDTVSTPVSGNELLQNSANPCYDPLTCHPREGEQCESGPCCRNCKFLKEGTICKRARGDDMDDYCNGKTCDCPRNPHKGPATAKGSVLM | proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Echis carinatus sochureki 3D-structure Cell adhesion impairing toxin Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Platelet aggregation inhibiting toxin Protease ... |
proteolysis | extracellular region | metal ion binding metalloendopeptidase activity toxin activity | Protobothrops elegans | Cell adhesion impairing toxin Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Platelet aggregation inhibiting toxin Protease Secreted Signal Toxin Zinc Zymogen | MIQVLLVTIC | MIQVLLVTICLAVFPYQGSSIILESGNVDDYEVVYPRKVTALPKGAVQPKYEDAMQYEFKVNGEAVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSVEDHCYYHGRIHNDADSTASISACDGLKGYFKLQGETYLIEPLELSDSEAHAVFKYENVEKEDEAPKMCGVTQNWESDESIKKASQLYLTPEQQRFPQRYIKLAIVVDHGMYTKYSSNFKKIRKRVHQMVSNINEMCRPLNIAITLALLDVWSEKDFITVQADAPTTAGLFGDWRERVLLKKKNHDHAQLLTDTNFARNTIGWAYLGRMCDEKYSVGVVQDH... | proteolysis extracellular region metal ion binding metalloendopeptidase activity toxin activity Protobothrops elegans Cell adhesion impairing toxin Direct protein sequencing Disulfide bond Hemostasis impairing toxin Hydrolase Metal-binding Metalloprotease Platelet aggregation inhibiting toxin Protease Secreted Signal ... |
suppression by virus of host toll-like receptor signaling pathway suppression by virus of host type I interferon production suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TB... | host cell cytoplasm; host cell nucleus; nucleus | protein sequestering activity | Vaccinia virus ) | Early protein Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host TBK1 by virus Inhibition of host TLR pathway by virus Reference proteome Viral immunoevasion | MNAYNKADSF | MNAYNKADSFSLESDSIKDVIHDYICWLSMTDEMRPSIGNVFKAMETFKIDAVRYYDGNIYELAKDINAMSFDGFIRSLQTIASKKDKLTVYGTMGLLSIVVDINKGCDISNIKFAAGIIILMEYIFDDTDMSHLKVALYRRIQRRDDVDR | suppression by virus of host toll-like receptor signaling pathway suppression by virus of host type I interferon production suppression by virus of host type I interferon-mediated signaling pathway suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TB... |
cellular response to calcium ion cellular response to UV ceramide biosynthetic process cholesterol metabolic process glycosphingolipid catabolic process negative regulation of MAP kinase activity nervous system development plasma membrane repair positive regulation of apoptotic process positive regulation of endocytosi... | endolysosome; endosome; extracellular exosome; extracellular space; lamellar body; lipid droplet; lysosomal lumen; lysosome; plasma membrane | acid sphingomyelin phosphodiesterase activity hydrolase activity, acting on glycosyl bonds phosphatidylcholine phospholipase C activity sphingomyelin phosphodiesterase activity zinc ion binding | Homo sapiens | 3D-structure Alternative splicing Direct protein sequencing Disease variant Disulfide bond Glycoprotein Glycosidase Host-virus interaction Hydrolase Lipid droplet Lipid metabolism Lysosome Metal-binding Neurodegeneration Niemann-Pick disease Phosphoprotein Reference proteome Secreted Signal Zinc | MPRYGASLRQ | MPRYGASLRQSCPRSGREQGQDGTAGAPGLLWMGLVLALALALALALALSDSRVLWAPAEAHPLSPQGHPARLHRIVPRLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGHWDIFSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADPLCCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPAGPFDMVYWTGDIPAHDVWHQTRQDQLRALTTVTALVRKFLGPVPVYPAVGN... | cellular response to calcium ion cellular response to UV ceramide biosynthetic process cholesterol metabolic process glycosphingolipid catabolic process negative regulation of MAP kinase activity nervous system development plasma membrane repair positive regulation of apoptotic process positive regulation of endocytosi... |
electron transport chain | plasma membrane; respirasome | flavin adenine dinucleotide binding oxidoreductase activity, acting on the CH-CH group of donors | Wolinella succinogenes | 3D-structure Cell inner membrane Cell membrane Electron transport FAD Flavoprotein Membrane Oxidoreductase Reference proteome Respiratory chain Transport | MKVQYCDSLV | MKVQYCDSLVIGGGLAGLRAAVATQQKGLSTIVLSLIPVKRSHSAAAQGGMQASLGNSKMSDGDNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIRELAAWGVPWTRIHKGDRMAIINAQKTTITEEDFRHGLIHSRDFGGTKKWRTCYTADATGHTMLFAVANECLKLGVSIQDRKEAIALIHQDGKCYGAVVRDLVTGDIIAYVAKGTLIATGGYGRIYKNTTNAVVCEGTGTAIALETGIAQLGNMEAVQFHPTPLFPSGILLTEGCRGDGGILRDVDGHRFMPDYEPEKKELASRDVVSRRMIEHIRKGKGVQS... | electron transport chain plasma membrane; respirasome flavin adenine dinucleotide binding oxidoreductase activity, acting on the CH-CH group of donors Wolinella succinogenes 3D-structure Cell inner membrane Cell membrane Electron transport FAD Flavoprotein Membrane Oxidoreductase Reference proteome Respiratory chain T... |
tricarboxylic acid cycle | plasma membrane; respirasome | metal ion binding oxidoreductase activity, acting on the CH-CH group of donors | Wolinella succinogenes | 3D-structure Cell inner membrane Cell membrane Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Reference proteome Respiratory chain Transmembrane Transmembrane helix Transport Tricarboxylic acid cycle | MTNESILESY | MTNESILESYSGVTPERKKSRMPAKLDWWQSATGLFLGLFMIGHMFFVSTILLGDNVMLWVTKKFELDFIFEGGKPIVVSFLAAFVFAVFIAHAFLAMRKFPINYRQYLTFKTHKDLMRHGDTTLWWIQAMTGFAMFFLGSVHLYIMMTQPQTIGPVSSSFRMVSEWMWPLYLVLLFAVELHGSVGLYRLAVKWGWFDGETPDKTRANLKKLKTLMSAFLIVLGLLTFGAYVKKGLEQTDPNIDYKYFDYKRTHHR | tricarboxylic acid cycle plasma membrane; respirasome metal ion binding oxidoreductase activity, acting on the CH-CH group of donors Wolinella succinogenes 3D-structure Cell inner membrane Cell membrane Direct protein sequencing Electron transport Heme Iron Membrane Metal-binding Reference proteome Respiratory chain T... |
acetyl-CoA metabolic process cellular response to cholesterol cellular response to follicle-stimulating hormone stimulus cellular response to low-density lipoprotein particle stimulus cellular response to organic cyclic compound cholesterol biosynthetic process farnesyl diphosphate biosynthetic process, mevalonate path... | cytoplasm | hydroxymethylglutaryl-CoA synthase activity isomerase activity organic acid binding protein homodimerization activity small molecule binding | Rattus norvegicus | Acetylation Cholesterol biosynthesis Cholesterol metabolism Cytoplasm Direct protein sequencing Lipid biosynthesis Lipid metabolism Phosphoprotein Reference proteome Steroid biosynthesis Steroid metabolism Sterol biosynthesis Sterol metabolism Transferase | MPGSLPLNAE | MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQARMGFCTDREDINSLCLTVVQKLMERNSLSYDCIGRLEVGTETIIDKSKSVKSNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAIYASGNARPTGGVGAVALLIGPNAPVIFDRGLRGTHMQHAYDFYKPDMLSEYPVVDGKLSIQCYLSALDRCYSVYRKKIRAQWQKEGKDKDFTLNDFGFMIFHSPYCKLVQKSLARMFLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFM... | acetyl-CoA metabolic process cellular response to cholesterol cellular response to follicle-stimulating hormone stimulus cellular response to low-density lipoprotein particle stimulus cellular response to organic cyclic compound cholesterol biosynthetic process farnesyl diphosphate biosynthetic process, mevalonate path... |
clathrin-dependent endocytosis intracellular protein transport negative regulation of hyaluronan biosynthetic process positive regulation of neuron projection development positive regulation of receptor-mediated endocytosis postsynaptic neurotransmitter receptor internalization vesicle-mediated transport | AP-2 adaptor complex; apical plasma membrane; basolateral plasma membrane; clathrin-coated vesicle; cytoplasmic side of plasma membrane; filopodium tip; membrane coat; postsynapse; protein-containing complex; secretory granule | clathrin adaptor activity low-density lipoprotein particle receptor binding protein kinase binding protein-containing complex binding | Mus musculus | Alternative splicing Cell membrane Coated pit Endocytosis Membrane Phosphoprotein Protein transport Reference proteome Transport | MPAVSKGDGM | MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMCLALHCIANVGSREMGEAFAADIPRILVAGDSMDSVKQSAALCLLRLYKASPDLVPMGEWTARVVHLLNDQHMGVVTAAVSLITCLCKKNPDDFKTCISLAVSRLSRIVSSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDAAVKGRLVECLETVLNKAQEPPKSKKVQHSNAKNAILFETISLIIHY... | clathrin-dependent endocytosis intracellular protein transport negative regulation of hyaluronan biosynthetic process positive regulation of neuron projection development positive regulation of receptor-mediated endocytosis postsynaptic neurotransmitter receptor internalization vesicle-mediated transport AP-2 adaptor c... |
clathrin-dependent endocytosis intracellular protein transport postsynaptic neurotransmitter receptor internalization regulation of hematopoietic stem cell differentiation vesicle-mediated transport | AP-2 adaptor complex; cytoplasmic side of plasma membrane; cytoplasmic vesicle; membrane coat; postsynapse; secretory granule; synaptic vesicle | clathrin adaptor activity disordered domain specific binding kinase binding phosphatidylinositol binding protein domain specific binding protein kinase binding protein serine/threonine kinase binding protein-containing complex binding | Mus musculus | 3D-structure Cell membrane Coated pit Endocytosis Lipid-binding Membrane Protein transport Reference proteome Transport | MPAVSKGDGM | MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHD... | clathrin-dependent endocytosis intracellular protein transport postsynaptic neurotransmitter receptor internalization regulation of hematopoietic stem cell differentiation vesicle-mediated transport AP-2 adaptor complex; cytoplasmic side of plasma membrane; cytoplasmic vesicle; membrane coat; postsynapse; secretory gra... |
chromatin remodeling negative regulation of transcription by RNA polymerase II nitrate assimilation positive regulation of transcription by RNA polymerase II regulation of amide catabolic process regulation of arginine metabolic process regulation of gene expression regulation of nitrogen utilization | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding zinc ion binding | Emericella nidulans | 3D-structure Activator DNA-binding Metal-binding Nitrate assimilation Nucleus Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MSGLTLGGGS | MSGLTLGGGSGRVRPTQAAAAFPTSHDFADPDRSSVARNANRPSRRFAAPPQLSDDFSLESPTDSAQVHDNLLQDALFPEWKANSPRGVDSPDEMQKKDPLATQIWKLYSRTKAQLPNQERMENLTWRMMALSLRRQERERAQQQARASSQKSPVPGMSGIAQLRLSDRVSNTPTTTADTVSDAMNLDDFIIPFSPSDHPSPSTTKASEATTGAIPIKARRDQSASEATPVPASFPHPAQDQRRESEFGYVPRRVRKTSIDERQFFNLQIPSRKRPAESSPHVPPVSTSMLAHDPDFSHAVPEYTLDTSHGLSLQNQMNA... | chromatin remodeling negative regulation of transcription by RNA polymerase II nitrate assimilation positive regulation of transcription by RNA polymerase II regulation of amide catabolic process regulation of arginine metabolic process regulation of gene expression regulation of nitrogen utilization nucleus DNA-bindin... |
carbohydrate metabolic process cell cycle cell division cell wall organization lipid glycosylation peptidoglycan biosynthetic process regulation of cell shape | plasma membrane | UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity | Escherichia coli | 3D-structure Cell cycle Cell division Cell inner membrane Cell membrane Cell shape Cell wall biogenesis/degradation Direct protein sequencing Glycosyltransferase Membrane Peptidoglycan synthesis Reference proteome Transferase | MSGQGKRLMV | MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGNPVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAG... | carbohydrate metabolic process cell cycle cell division cell wall organization lipid glycosylation peptidoglycan biosynthetic process regulation of cell shape plasma membrane UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylg... |
glycine betaine biosynthetic process from choline response to osmotic stress | membrane; plasma membrane | betaine-aldehyde dehydrogenase activity choline dehydrogenase activity flavin adenine dinucleotide binding | Escherichia coli | Cell membrane FAD Flavoprotein Membrane NAD Oxidoreductase Reference proteome Stress response | MQFDYIIIGA | MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQEPGLENWSYLDCLPYYRKAETRDMGENDYHGGDGPVSVTTSKPGVNPLFEAMIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRTHAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQW... | glycine betaine biosynthetic process from choline response to osmotic stress membrane; plasma membrane betaine-aldehyde dehydrogenase activity choline dehydrogenase activity flavin adenine dinucleotide binding Escherichia coli Cell membrane FAD Flavoprotein Membrane NAD Oxidoreductase Reference proteome Stress response... |
glycine betaine biosynthetic process from choline protein homotetramerization response to osmotic stress response to X-ray | cytosol; protein-containing complex | betaine-aldehyde dehydrogenase activity identical protein binding metal ion binding | Escherichia coli | Direct protein sequencing Metal-binding NAD NADP Oxidation Oxidoreductase Potassium Reference proteome Stress response | MSRMAEQQLY | MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGREDVDRAVKSAQQGQKIWASMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETSTVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMMANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDVFD... | glycine betaine biosynthetic process from choline protein homotetramerization response to osmotic stress response to X-ray cytosol; protein-containing complex betaine-aldehyde dehydrogenase activity identical protein binding metal ion binding Escherichia coli Direct protein sequencing Metal-binding NAD NADP Oxidation O... |
acute-phase response cellular defense response defense response to Gram-negative bacterium innate immune response lipid transport macrophage activation involved in immune response opsonization positive regulation of tumor necrosis factor production | extracellular space | lipopolysaccharide binding signaling receptor binding | Oryctolagus cuniculus | Antibiotic Antimicrobial Direct protein sequencing Disulfide bond Glycoprotein Immunity Innate immunity Lipid transport Reference proteome Secreted Signal Transport | MGTWARALLG | MGTWARALLGSTLLSLLLAAAPGALGTNPGLITRITDKGLEYAAREGLLALQRKLLEVTLPDSDGDFRIKHFGRAQYKFYSLKIPRFELLRGTLRPLPGQGLSLDISDAYIHVRGSWKVRKAFLRLKNSFDLYVKGLTISVHLVLGSESSGRPTVTTSSCSSDIQNVELDIEGDLEELLNLLQSQIDARLREVLESKICRQIEEAVTAHLQPYLQTLPVTTQIDSFAGIDYSLMEAPRATAGMLDVMFKGEIFPLDHRSPVDFLAPAMNLPEAHSRMVYFSISDYVFNTASLAYHKSGYWNFSITDAMVPADLNIRRTTK... | acute-phase response cellular defense response defense response to Gram-negative bacterium innate immune response lipid transport macrophage activation involved in immune response opsonization positive regulation of tumor necrosis factor production extracellular space lipopolysaccharide binding signaling receptor bindi... |
adhesion receptor-mediated virion attachment to host cell clathrin-dependent endocytosis of virus by host cell entry receptor-mediated virion attachment to host cell microtubule-dependent intracellular transport of viral material towards nucleus permeabilization of host organelle membrane involved in viral entry into h... | host cell nucleus; T=1 icosahedral viral capsid | metal ion binding structural molecule activity | Canine parvovirustype 2 | 3D-structure Alternative splicing Capsid protein Clathrin-mediated endocytosis of virus by host Cytoplasmic inwards viral transport Disulfide bond Host nucleus Host-virus interaction Magnesium Metal-binding Microtubular inwards viral transport T=1 icosahedral capsid protein Viral attachment to host adhesion receptor Vi... | MAPPAKRARR | MAPPAKRARRGLVPPGYKYLGPGNSLDQGEPTNPSDAAAKEHDEAYAAYLRSGKNPYLYFSPADQRFIDQTKDAKDWGGKIGHYFFRAKKAIAPVLTDTPDHPSTSRPTKPTKRSKPPPHIFINLAKKKKAGAGQVKRDNLAPMSDGAVQPDGGQPAVRNERATGSGNGSGGGGGGGSGGVGISTGTFNNQTEFKFLENGWVEITANSSRLVHLNMPESENYRRVVVNNMDKTAVNGNMALDDIHAQIVTPWSLVDANAWGVWFNPGDWQLIVNTMSELHLVSFEQEIFNVVLKTVSESATQPPTKVYNNDLTASLMVAL... | adhesion receptor-mediated virion attachment to host cell clathrin-dependent endocytosis of virus by host cell entry receptor-mediated virion attachment to host cell microtubule-dependent intracellular transport of viral material towards nucleus permeabilization of host organelle membrane involved in viral entry into h... |
acute-phase response response to chromate response to cytokine response to estradiol response to hypoxia response to inorganic substance response to lead ion response to lipopolysaccharide response to methanol response to organic cyclic compound response to triglyceride | endoplasmic reticulum; extracellular space; Golgi apparatus | endopeptidase inhibitor activity identical protein binding protease binding serine-type endopeptidase inhibitor activity | Rattus norvegicus | Acute phase Direct protein sequencing Glycoprotein Phosphoprotein Protease inhibitor Reference proteome Secreted Serine protease inhibitor Signal | MAPSISRGLL | MAPSISRGLLLLAALCCLAPSFLAEDAQETDTSQQDQSPTYRKISSNLADFAFSLYRELVHQSNTSNIFFSPMSITTAFAMLSLGSKGDTRKQILEGLEFNLTQIPEADIHKAFHHLLQTLNRPDSELQLNTGNGLFVNKNLKLVEKFLEEVKNNYHSEAFSVNFADSEEAKKVINDYVEKGTQGKIVDLMKQLDEDTVFALVNYIFFKGKWKRPFNPEHTRDADFHVDKSTTVKVPMMNRLGMFDMHYCSTLSSWVLMMDYLGNATAIFLLPDDGKMQHLEQTLTKDLISRFLLNRQTRSAILYFPKLSISGTYNLKTL... | acute-phase response response to chromate response to cytokine response to estradiol response to hypoxia response to inorganic substance response to lead ion response to lipopolysaccharide response to methanol response to organic cyclic compound response to triglyceride endoplasmic reticulum; extracellular space; Golgi... |
positive regulation of transcription by RNA polymerase I transcription by RNA polymerase I transcription initiation at RNA polymerase I promoter | fibrillar center; nucleolus; nucleoplasm; nucleus | chromatin binding RNA binding RNA polymerase I cis-regulatory region sequence-specific DNA binding RNA polymerase I core promoter sequence-specific DNA binding RNA polymerase I general transcription initiation factor activity scaffold protein binding | Homo sapiens | 3D-structure Acetylation Activator Alternative splicing Disease variant DNA-binding Intellectual disability Neurodegeneration Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation | MNGEADCPTD | MNGEADCPTDLEMAAPKGQDRWSQEDMLTLLECMKNNLPSNDSSKFKTTESHMDWEKVAFKDFSGDMCKLKWVEISNEVRKFRTLTELILDAQEHVKNPYKGKKLKKHPDFPKKPLTPYFRFFMEKRAKYAKLHPEMSNLDLTKILSKKYKELPEKKKMKYIQDFQREKQEFERNLARFREDHPDLIQNAKKSDIPEKPKTPQQLWYTHEKKVYLKVRPDATTKEVKDSLGKQWSQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQLKDKFDGRPTKPPPNSYSLYCAELMANMKDVP... | positive regulation of transcription by RNA polymerase I transcription by RNA polymerase I transcription initiation at RNA polymerase I promoter fibrillar center; nucleolus; nucleoplasm; nucleus chromatin binding RNA binding RNA polymerase I cis-regulatory region sequence-specific DNA binding RNA polymerase I core prom... |
adult locomotory behavior anterior/posterior pattern specification dorsal spinal cord development embryonic skeletal system morphogenesis grooming behavior negative regulation of myeloid cell differentiation regulation of transcription by RNA polymerase II sensory perception of pain | chromatin; nucleoplasm; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MSSYFVNSLF | MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKGDKK | adult locomotory behavior anterior/posterior pattern specification dorsal spinal cord development embryonic skeletal system morphogenesis grooming behavior negative regulation of myeloid cell differentiation regulation of transcription by RNA polymerase II sensory perception of pain chromatin; nucleoplasm; nucleus DNA-... |
anterior/posterior pattern specification cell chemotaxis DNA-templated transcription embryonic skeletal system morphogenesis mammary gland development positive regulation of transcription by RNA polymerase II proximal/distal pattern formation regulation of transcription by RNA polymerase II | chromatin; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Developmental protein DNA-binding Homeobox Isopeptide bond Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Ubl conjugation | MSISGTLSSY | MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE | anterior/posterior pattern specification cell chemotaxis DNA-templated transcription embryonic skeletal system morphogenesis mammary gland development positive regulation of transcription by RNA polymerase II proximal/distal pattern formation regulation of transcription by RNA polymerase II chromatin; nucleoplasm; nucl... |
anterior/posterior pattern specification bone marrow development definitive hemopoiesis embryonic skeletal system morphogenesis hematopoietic stem cell differentiation hematopoietic stem cell proliferation morphogenesis of an epithelial sheet negative regulation of transcription by RNA polymerase II positive regulation... | centrosome; chromatin; nucleoplasm | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MAMSSFLINS | MAMSSFLINSNYVDPKFPPCEEYSQSDYLPSDHSPGYYAGGQRRESSFQPEAGFGRRAACTVQRYAACRDPGPPPPPPPPPPPPPPPGLSPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMRKVHVSTVNPNYAGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGAAGSAGGPPGRPNGGPRAL | anterior/posterior pattern specification bone marrow development definitive hemopoiesis embryonic skeletal system morphogenesis hematopoietic stem cell differentiation hematopoietic stem cell proliferation morphogenesis of an epithelial sheet negative regulation of transcription by RNA polymerase II positive regulation... |
anterior/posterior pattern specification cell fate specification defense response to bacterium hindgut development negative regulation of transcription by RNA polymerase II nematode male tail tip morphogenesis neuron migration positive regulation of transcription by RNA polymerase II regulation of cell adhesion regulat... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II-specific DNA-binding transcription factor binding | Caenorhabditis elegans | Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Reference proteome | MNTSTSAFDF | MNTSTSAFDFGSSTASSAATSTTSSQPDANDHLSRLAAMTQGVGKEDPETSSTPSTEASLYPGISAAYMQSYGWPQNYNYFGQPLGPATFPGWPQCYPNTAWPNYGELFASSKKGRQTYQRYQTSVLEAKFQQSSYVSKKQREELRLQTQLTDRQIKIWFQNRRMKAKKEKQRVDDHTEHTPLLPANPPKGMGMDMDDEKKWQMAHWPPAAAHNPYQYPLCPP | anterior/posterior pattern specification cell fate specification defense response to bacterium hindgut development negative regulation of transcription by RNA polymerase II nematode male tail tip morphogenesis neuron migration positive regulation of transcription by RNA polymerase II regulation of cell adhesion regulat... |
hemoglobin biosynthetic process male gonad development negative regulation of follicle-stimulating hormone secretion ovarian follicle development regulation of cell cycle regulation of cell population proliferation | extracellular space; inhibin A complex; inhibin B complex; inhibin-betaglycan-ActRII complex; neuronal cell body; photoreceptor inner segment; photoreceptor outer segment | cytokine activity growth factor activity hormone activity inhibin binding protein-containing complex binding signaling receptor binding | Rattus norvegicus | Cleavage on pair of basic residues Disulfide bond Glycoprotein Growth factor Hormone Reference proteome Secreted Signal | MVIQPSLLLL | MVIQPSLLLLLLLTLQDVDSCQGPELVRELVLAKVKALFLDALGPPAMDGEGGGPGIRRLPRRHALGGFMHRTSEPEEEDVSQAILFPATGATCEDQAAAGGLAQEPEEGLFTYVFRPSQHIRSHQVTSAQLWFHTGLDRKSTAASNSSRPLLDLLVLSSGGPMAVPVSLGQSPPRWAVLHLAASAFPLLTHPILVLLLRCPLCSCSGRPETTPFLVAHTRARAPSAGERARRSAPSMPWPWSPAALRLLQRPPEEPSAHAFCHRAALNISFQELGWDRWIVHPPSFIFHYCHGSCGMPTSDLPLPVPGAPPTPAQPLFL... | hemoglobin biosynthetic process male gonad development negative regulation of follicle-stimulating hormone secretion ovarian follicle development regulation of cell cycle regulation of cell population proliferation extracellular space; inhibin A complex; inhibin B complex; inhibin-betaglycan-ActRII complex; neuronal ce... |
fusion of virus membrane with host endosome membrane membrane fusion involved in viral entry into host cell modulation by virus of host process viral budding from plasma membrane viral entry into host cell | host cell plasma membrane; membrane; viral envelope; virion membrane | identical protein binding | Autographa californica nuclear polyhedrosis virus | 3D-structure Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host membrane Lipoprotein Membrane Palmitate Phosphoprotein Reference proteome Signal Transmembrane Transmembrane helix Viral envelope protein Viral penetration i... | MVSAIVLYVL | MVSAIVLYVLLAAAAHSAFAAEHCNAQMKTGPYKIKNLDITPPKETLQKDVEITIVETDYNENVIIGYKGYYQAYAYNGGSLDPNTRVEETMKTLNVGKEDLLMWSIRQQCEVGEELIDRWGSDSDDCFRDNEGRGQWVKGKELVKRQNNNHFAHHTCNKSWRCGISTSKMYSRLECQDDTDECQVYILDAEGNPINVTVDTVLHRDGVSMILKQKSTFTTRQIKAACLLIKDDKNNPESVTREHCLIDNDIYDLSKNTWNCKFNRCIKRKVEHRVKKRPPTWRHNVRAKYTEGDTATKGDLMHIQEELMYENDLLKMNI... | fusion of virus membrane with host endosome membrane membrane fusion involved in viral entry into host cell modulation by virus of host process viral budding from plasma membrane viral entry into host cell host cell plasma membrane; membrane; viral envelope; virion membrane identical protein binding Autographa californ... |
aerobic respiration malate metabolic process tricarboxylic acid cycle | cytoplasm; mitochondrial matrix; mitochondrion | L-malate dehydrogenase activity mRNA binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Mitochondrion NAD Oxidoreductase Phosphoprotein Reference proteome Transit peptide Tricarboxylic acid cycle | MLSRVAKRAF | MLSRVAKRAFSSTVANPYKVTVLGAGGGIGQPLSLLLKLNHKVTDLRLYDLKGAKGVATDLSHIPTNSVVKGFTPEEPDGLNNALKDTDMVLIPAGVPRKPGMTRDDLFAINASIVRDLAAATAESAPNAAILVISNPVNSTVPIVAQVLKNKGVYNPKKLFGVTTLDSIRAARFISEVENTDPTQERVNVIGGHSGITIIPLISQTNHKLMSDDKRHELIHRIQFGGDEVVKAKNGAGSATLSMAHAGAKFANAVLSGFKGERDVIEPSFVDSPLFKSEGIEFFASPVTLGPDGIEKIHPIGELSSEEEEMLQKCKETL... | aerobic respiration malate metabolic process tricarboxylic acid cycle cytoplasm; mitochondrial matrix; mitochondrion L-malate dehydrogenase activity mRNA binding Saccharomyces cerevisiae 3D-structure Direct protein sequencing Mitochondrion NAD Oxidoreductase Phosphoprotein Reference proteome Transit peptide Tricarboxy... |
anterior/posterior pattern specification embryonic skeletal system morphogenesis erythrocyte homeostasis regulation of transcription by RNA polymerase II | chromatin; nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding | Homo sapiens | Alternative splicing Developmental protein DNA-binding Homeobox Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSSYFVNSTF | MSSYFVNSTFPVTLASGQESFLGQLPLYSSGYADPLRHYPAPYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRKSDCAQDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSGRRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEKQAE | anterior/posterior pattern specification embryonic skeletal system morphogenesis erythrocyte homeostasis regulation of transcription by RNA polymerase II chromatin; nucleus DNA-binding transcription factor activity, RNA polymerase II-specific RNA binding RNA polymerase II cis-regulatory region sequence-specific DNA bin... |
proteolysis viral process | membrane | RNA binding serine-type endopeptidase activity serine-type exopeptidase activity | Potato leafroll virus | Direct protein sequencing Hydrolase Membrane Protease Reference proteome Ribosomal frameshifting RNA-binding Serine protease Signal Transmembrane Transmembrane helix | MNRFTAYAAL | MNRFTAYAALFFMFSLCSTAKEAGFLHPAFNFRGTSTMSASSGDYSAAPTPLYKSWALPSSLNLTTQPPPPLTDRSYYELVQALTSKMRLDCQTVGDMTWRHLSEMLFASWNSVKEVSLKAASVTLWAIINIWFGLYWTLARLITLFLWTFSIEALCLILLGCITSLIYKGALSLSEHLPVFLFMSPLKIIWRAAFSKRNYKNERAVEGYKGFSVPQKPPKSAVIELQHENGSHLGYANCIRLYSGENALVTAEHCLEGAFATSLKTGNRIPMSTFFPIFKSARNDISILVGPPNWEGLLSVKGAHFITADKIGKGPASF... | proteolysis viral process membrane RNA binding serine-type endopeptidase activity serine-type exopeptidase activity Potato leafroll virus Direct protein sequencing Hydrolase Membrane Protease Reference proteome Ribosomal frameshifting RNA-binding Serine protease Signal Transmembrane Transmembrane helix MNRFTAYAAL MNRF... |
aromatic amino acid metabolic process bone remodeling circadian rhythm mammary gland alveolus development negative regulation of ossification platelet degranulation positive regulation of fat cell differentiation regulation of hemostasis response to immobilization stress serotonin biosynthetic process | cytoplasm; neuron projection | iron ion binding tryptophan 5-monooxygenase activity | Mus musculus | Iron Metal-binding Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Serotonin biosynthesis Ubl conjugation | MIEDNKENKE | MIEDNKENKENKDHSSERGRVTLIFSLENEVGGLIKVLKIFQENHVSLLHIESRKSKQRNSEFEIFVDCDISREQLNDIFPLLKSHATVLSVDSPDQLTAKEDVMETVPWFPKKISDLDFCANRVLLYGSELDADHPGFKDNVYRRRRKYFAELAMNYKHGDPIPKIEFTEEEIKTWGTIFRELNKLYPTHACREYLRNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEETVQKLATCYFFTVE... | aromatic amino acid metabolic process bone remodeling circadian rhythm mammary gland alveolus development negative regulation of ossification platelet degranulation positive regulation of fat cell differentiation regulation of hemostasis response to immobilization stress serotonin biosynthetic process cytoplasm; neuron... |
antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... | azurophil granule; extracellular space; intracellular membrane-bounded organelle; midbody; secretory granule | pore-forming activity protein homodimerization activity | Mus musculus | Antimicrobial Defensin Reference proteome Repeat Secreted Signal | MKKLVLLFAL | MKKLVLLFALVLLAFQVQADSIQNTDEETKTEEQPGEKDQAVSVSFGDPQGSALQDAALGWGRRCPQCPRCPSCPSCPRCPRCPRCKCNPK | antibacterial humoral response antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium disruption of plasma membrane integrity in another organism... |
cellular response to calcium ion gene expression negative regulation of transcription by RNA polymerase II osteoblast development positive regulation of osteoblast differentiation positive regulation of transcription by RNA polymerase II regulation of cell cycle regulation of cell population proliferation regulation of... | chromatin; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex; transcription factor AP-1 complex; transcription regulator complex; transcription repressor complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific enzyme binding RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding tr... | Homo sapiens | 3D-structure Activator Disulfide bond DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | METPFYGDEA | METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAAALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSSQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPGELAPAAAAPEAPVYANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALKDEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQ... | cellular response to calcium ion gene expression negative regulation of transcription by RNA polymerase II osteoblast development positive regulation of osteoblast differentiation positive regulation of transcription by RNA polymerase II regulation of cell cycle regulation of cell population proliferation regulation of... |
muscle contraction phosphocreatine biosynthetic process phosphorylation | mitochondrial inner membrane; mitochondrion | ATP binding creatine kinase activity | Homo sapiens | 3D-structure ATP-binding Direct protein sequencing Kinase Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference proteome Transferase Transit peptide | MASIFSKLLT | MASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSN... | muscle contraction phosphocreatine biosynthetic process phosphorylation mitochondrial inner membrane; mitochondrion ATP binding creatine kinase activity Homo sapiens 3D-structure ATP-binding Direct protein sequencing Kinase Membrane Mitochondrion Mitochondrion inner membrane Nucleotide-binding Phosphoprotein Reference ... |
negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II | chromatin; chromosome, telomeric region; cytoplasm; nucleoplasm; nucleus; RNA polymerase II transcription regulator complex | cAMP response element binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific enzyme binding metal ion binding mitogen-activated protein kinase binding RNA polymerase II cis-regulator... | Homo sapiens | Activator Alternative splicing Chromosome Cytoplasm DNA-binding Host-virus interaction Isopeptide bond Metal-binding Nucleus Phosphoprotein Reference proteome Telomere Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MGDDRPFVCN | MGDDRPFVCNAPGCGQRFTNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNCEEVGLFNELASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSNRQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSGSISPSGHPIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQSQILIQHPDAPSPAQPQVSPAQPTPSTG... | negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II chromatin; chromosome, telomeric region; cytoplasm; nucleoplasm; nucleus; RNA polymerase II transcription regulat... |
actin filament depolymerization actin filament organization actin filament severing cAMP-mediated signaling positive regulation of actin filament depolymerization positive regulation of mitochondrial fission positive regulation of Ras protein signal transduction Ras protein signal transduction regulation of actin filam... | actin cortical patch; cytoplasm; mating projection tip | actin binding adenylate cyclase binding identical protein binding | Saccharomyces cerevisiae | 3D-structure Actin-binding Cytoplasm Cytoskeleton Phosphoprotein Reference proteome | MPDSKYTMQG | MPDSKYTMQGYNLVKLLKRLEEATARLEDVTIYQEGYIQNKLEASKNNKPSDSGADANTTNEPSAENAPEVEQDPKCITAFQSYIGENIDPLVELSGKIDTVVLDALQLLKGGFQSQLTFLRAAVRSRKPDYSSQTFADSLRPINENIIKLGQLKESNRQSKYFAYLSALSEGAPLFSWVAVDTPVSMVTDFKDAAQFWTNRILKEYRESDPNAVEWVKKFLASFDNLKAYIKEYHTTGVSWKKDGMDFADAMAQSTKNTGATSSPSPASATAAPAPPPPPPAPPASVFEISNDTPATSSDANKGGIGAVFAELNQGENI... | actin filament depolymerization actin filament organization actin filament severing cAMP-mediated signaling positive regulation of actin filament depolymerization positive regulation of mitochondrial fission positive regulation of Ras protein signal transduction Ras protein signal transduction regulation of actin filam... |
alanine catabolic process L-alanine catabolic process sporulation resulting in formation of a cellular spore | cytosol | alanine dehydrogenase activity nucleotide binding | Lysinibacillus sphaericus | Cytoplasm Direct protein sequencing NAD Nucleotide-binding Oxidoreductase Sporulation | MKIGIPKEIK | MKIGIPKEIKNNENRVAMTPAGVVSLTHAGHERLAIETGGGIGSSFTDAEYVAAGAAYRCIGKEAWAQEMILKVKEPVASEYDYFYEGQILFTYLHLAPRAELTQALIDKKVVGIAYETVQLANGSLPLLTPMSEVAGKMATQIGAQYLEKNHGGKGILLGGVSGVHARKVTVIGGGIAGTNAAKIAVGMGADVTVIDLSPERLRQLEDMFGRDVQTLMSNPYNIAESVKHSDLVVGAVLIPGAKAPKLVSEEMIQSMQPGSVVVDIAIDQGGIFATSDRVTTHDDPTYVKHGVVHYAVANMPGAVPRTSTIALTNNTIP... | alanine catabolic process L-alanine catabolic process sporulation resulting in formation of a cellular spore cytosol alanine dehydrogenase activity nucleotide binding Lysinibacillus sphaericus Cytoplasm Direct protein sequencing NAD Nucleotide-binding Oxidoreductase Sporulation MKIGIPKEIK MKIGIPKEIKNNENRVAMTPAGVVSLTHAG... |
negative regulation of interleukin-13 production negative regulation of interleukin-4 production negative regulation of interleukin-5 production negative regulation of T cell proliferation negative regulation of transcription by RNA polymerase II negative regulation of type II interferon production regulation of inflam... | cytoplasm; extracellular space; nuclear envelope; secretory granule | phospholipase A2 inhibitor activity polychlorinated biphenyl binding | Rattus norvegicus | 3D-structure Disulfide bond Phospholipase A2 inhibitor Reference proteome Secreted Signal | MKIAITITVL | MKIAITITVLMLSICCSSASSDICPGFLQVLEALLLGSESNYEAALKPFNPASDLQNAGTQLKRLVDTLPQETRINIVKLTEKILTSPLCEQDLRV | negative regulation of interleukin-13 production negative regulation of interleukin-4 production negative regulation of interleukin-5 production negative regulation of T cell proliferation negative regulation of transcription by RNA polymerase II negative regulation of type II interferon production regulation of inflam... |
one-carbon metabolic process S-adenosylmethionine biosynthetic process | cytosol; extracellular exosome; nucleolus; plant-type cell wall; plasmodesma | ATP binding copper ion binding methionine adenosyltransferase activity | Arabidopsis thaliana | 3D-structure ATP-binding Cobalt Cytoplasm Magnesium Metal-binding Nucleotide-binding One-carbon metabolism Potassium Reference proteome Transferase | METFLFTSES | METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATIDYEKIVRDTCRSIGFISDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKRPEDIGAGDQGHMFGYATDETPELMPLSHVLATKIGARLTEVRKNGTCRWLRPDGKTQVTVEYYNDNGAMVPVRVHTVLISTQHDETVTNDEIARDLKEHVIKPIIPEKYLDDKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARRALVQVSYAIGVPEPLSVFV... | one-carbon metabolic process S-adenosylmethionine biosynthetic process cytosol; extracellular exosome; nucleolus; plant-type cell wall; plasmodesma ATP binding copper ion binding methionine adenosyltransferase activity Arabidopsis thaliana 3D-structure ATP-binding Cobalt Cytoplasm Magnesium Metal-binding Nucleotide-bin... |
brown fat cell differentiation protein transport | cytosol; fibrillar center; membrane; nucleolus | methanethiol oxidase activity selenium binding | Mus musculus | Acetylation Cytoplasm Membrane Nucleus Oxidoreductase Phosphoprotein Protein transport Reference proteome Selenium Transport | MATKCTKCGP | MATKCTKCGPGYSTPLEAMKGPREEIVYLPCIYRNTGTEAPDYLATVDVDPKSPQYSQVIHRLPMPYLKDELHHSGWNTCSSCFGDSTKSRNKLILPGLISSRIYVVDVGSEPRAPKLHKVIEASEIQAKCNVSSLHTSHCLASGEVMVSTLGDLQGNGKGSFVLLDGETFEVKGTWEKPGDAAPMGYDFWYQPRHNVMVSTEWAAPNVFKDGFNPAHVEAGLYGSRIFVWDWQRHEIIQTLQMTDGLIPLEIRFLHDPSATQGFVGCALSSNIQRFYKNAEGTWSVEKVIQVPSKKVKGWMLPEMPGLITDILLSLDDR... | brown fat cell differentiation protein transport cytosol; fibrillar center; membrane; nucleolus methanethiol oxidase activity selenium binding Mus musculus Acetylation Cytoplasm Membrane Nucleus Oxidoreductase Phosphoprotein Protein transport Reference proteome Selenium Transport MATKCTKCGP MATKCTKCGPGYSTPLEAMKGPREEIVY... |
apoptotic process endoplasmic reticulum unfolded protein response negative regulation of cell population proliferation negative regulation of peptidyl-threonine phosphorylation negative regulation of protein dephosphorylation negative regulation of protein processing negative regulation of transcription by RNA polymera... | cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; membrane; mitochondrial outer membrane; mitochondrion; protein phosphatase type 1 complex | protein kinase binding protein phosphatase 1 binding protein phosphatase binding protein phosphatase regulator activity | Mus musculus | Alternative splicing Apoptosis Endoplasmic reticulum Membrane Mitochondrion Mitochondrion outer membrane Phosphoprotein Reference proteome Repeat Stress response Translation regulation Ubl conjugation | MAPSPRPQHV | MAPSPRPQHVLHWRDAHNFYLLSPLMGLLSRAWSRLRGPEVPEAWLAKTVTGADQIEAAALLTPTPVSGNLLPHGETEESGSPEQSQAAQRLCLVEAESSPPETWGLSNVDEYNAKPGQDDLREKEMERTAGKATLQPAGLQGADKRLGEVVAREEGVAEPAYPTSQLEGGPAENEEDGETVKTYQASAASIAPGYKPSTPVPFLGEAEHQATEEKGTENKADPSNSPSSGSHSRAWEYYSREKPKQEGEAKVEAHRAGQGHPCRNAEAEEGGPETTFVCTGNAFLKAWVYRPGEDTEEEDNSDSDSAEEDTAQTGATPH... | apoptotic process endoplasmic reticulum unfolded protein response negative regulation of cell population proliferation negative regulation of peptidyl-threonine phosphorylation negative regulation of protein dephosphorylation negative regulation of protein processing negative regulation of transcription by RNA polymera... |
lipid catabolic process | extracellular region | triglyceride lipase activity | Geotrichum candidum | Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Pyrrolidone carboxylic acid Secreted Signal | MVSKTFFLAA | MVSKTFFLAAALNVVGTLAQAPTAVLNGNEVISGVLEGKVDTFKGIPFADPPVGDLRFKHPQPFTGSYQGLKANDFSSACMQLDPGNAISLLDKVVGLGKIIPDNLRGPLYDMAQGSVSMNEDCLYLNVFRPAGTKPDAKLPVMVWIYGGAFVFGSSASYPGNGYVKESVEMGQPVVFVSINYRTGPYGFLGGDAITAEGNTNAGLHDQRKGLEWVSDNIANFGGDPDKVMIFGESAGAMSVAHQLVAYGGDNTYNGKQLFHSAILQSGGPLPYFDSTSVGPESAYSRFAQYAGCDASAGDNETLACLRSKSSDVLHSAQ... | lipid catabolic process extracellular region triglyceride lipase activity Geotrichum candidum Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Pyrrolidone carboxylic acid Secreted Signal MVSKTFFLAA MVSKTFFLAAALNVVGTLAQAPTAVLNGNEVISGVLEGKVDTFKGIPFADPPVGDLRFKHPQPFTGSYQGL... |
cellular response to streptomycin | cytoplasm | adenylyltransferase activity protein homodimerization activity | Bacillus subtilis | 3D-structure Cytoplasm Nucleotidyltransferase Reference proteome Transferase | MRSEQEMMDI | MRSEQEMMDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQWLEIFGKRIMMQKPEDMELFPPELGNWFSYIILFEDGNKLDLTLIPIREAEDYFANNDGLVKVLLDKDSFINYKVTPNDRQYWIKRPTAREFDDCCNEFWMVSTYVVKGLARNEILFAIDHLNEIVRPNLLRMMAWHIASQKGYSFSMGKNYKFMKRYLSNKEWEELMSTYSVNGYQEMWKSLFTCYALFRKYSKAVSEGLAYKYPDYDEGITKYTEGIYCSVK | cellular response to streptomycin cytoplasm adenylyltransferase activity protein homodimerization activity Bacillus subtilis 3D-structure Cytoplasm Nucleotidyltransferase Reference proteome Transferase MRSEQEMMDI MRSEQEMMDIFLDFALNDERIRLVTLEGSRTNRNIPPDNFQDYDISYFVTDVESFKENDQWLEIFGKRIMMQKPEDMELFPPELGNWFSYIILFEDGNKLDLTLIPI... |
isoleucine biosynthetic process response to herbicide valine biosynthetic process | chloroplast; chloroplast stroma | acetolactate synthase activity flavin adenine dinucleotide binding magnesium ion binding thiamine pyrophosphate binding | Arabidopsis thaliana | 3D-structure Amino-acid biosynthesis Branched-chain amino acid biosynthesis Chloroplast Coiled coil FAD Flavoprotein Genetically modified food Herbicide resistance Magnesium Metal-binding Oxidation Plastid Reference proteome Thiamine pyrophosphate Transferase Transit peptide | MAAATTTTTT | MAAATTTTTTSSSISFSTKPSPSSSKSPLPISRFSLPFSLNPNKSSSSSRRRGIKSSSPSSISAVLNTTTNVTTTPSPTKPTKPETFISRFAPDQPRKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSSGKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLPGYMSRMPKPPEDSHLEQIVRLISESKKPVLYVGGGCLNSSDELGRF... | isoleucine biosynthetic process response to herbicide valine biosynthetic process chloroplast; chloroplast stroma acetolactate synthase activity flavin adenine dinucleotide binding magnesium ion binding thiamine pyrophosphate binding Arabidopsis thaliana 3D-structure Amino-acid biosynthesis Branched-chain amino acid bi... |
hydrogen peroxide catabolic process response to hydrogen peroxide seed germination | cytoplasm; glyoxysome; nucleus; peroxisome; plasma membrane | catalase activity heme binding metal ion binding | Gossypium hirsutum | Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Peroxisome Reference proteome | MDPYKHRPSS | MDPYKHRPSSAFNSPFWTTNSGAPVWNNNSSLTVGPRGQYLLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFIRDGMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFTFLFDDLGVPQDYRHMEGSGVNTYTLINKAGKAHYVKFHWKPTCGVKCLLEDEAIKVGGANHSHATQDLYDSIAAGNYPEWKLFIQTIDPDHEDKFDFDPLDVTKTWPEDILPLQPVGRLVLNKNIDNFFAENE... | hydrogen peroxide catabolic process response to hydrogen peroxide seed germination cytoplasm; glyoxysome; nucleus; peroxisome; plasma membrane catalase activity heme binding metal ion binding Gossypium hirsutum Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Peroxisome Reference proteome MDPYKHRPSS... |
chemical synaptic transmission neuron development neurotransmitter secretion regulation of neurotransmitter secretion regulation of synaptic vesicle cycle regulation of synaptic vesicle exocytosis synapse organization synaptic vesicle clustering | axon; cell body; cytoskeleton; dendrite; extrinsic component of synaptic vesicle membrane; Golgi apparatus; postsynaptic density; presynapse; presynaptic active zone; Schaffer collateral - CA1 synapse; synaptic vesicle; synaptic vesicle membrane; synaptonemal complex | actin binding ATP binding calcium-dependent protein binding cytoskeletal protein-membrane anchor activity identical protein binding protein kinase binding | Homo sapiens | Actin-binding Alternative splicing Cell projection Cytoplasmic vesicle Disease variant Epilepsy Glycoprotein Golgi apparatus Intellectual disability Methylation Phosphoprotein Reference proteome Repeat Synapse | MNYLRRRLSD | MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKTYATAEPFIDAKYDVRVQKIG... | chemical synaptic transmission neuron development neurotransmitter secretion regulation of neurotransmitter secretion regulation of synaptic vesicle cycle regulation of synaptic vesicle exocytosis synapse organization synaptic vesicle clustering axon; cell body; cytoskeleton; dendrite; extrinsic component of synaptic v... |
proton motive force-driven ATP synthesis | mitochondrial proton-transporting ATP synthase complex; proton-transporting ATP synthase complex, coupling factor F(o) | lipid binding proton transmembrane transporter activity | Ovis aries | 3D-structure CF(0) Direct protein sequencing Hydrogen ion transport Ion transport Lipid-binding Membrane Methylation Mitochondrion Reference proteome Transit peptide Transmembrane Transmembrane helix Transport | MQTTGALLIS | MQTTGALLISPALIRSCTRGLIRPVSASFLSRPEIPSVQPSYSSGPLQVARREFQTSVVSRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM | proton motive force-driven ATP synthesis mitochondrial proton-transporting ATP synthase complex; proton-transporting ATP synthase complex, coupling factor F(o) lipid binding proton transmembrane transporter activity Ovis aries 3D-structure CF(0) Direct protein sequencing Hydrogen ion transport Ion transport Lipid-bindi... |
malate metabolic process | chloroplast | malate dehydrogenase (NADP+) activity | Sorghum bicolor | 3D-structure Chloroplast Disulfide bond NADP Oxidoreductase Plastid Transit peptide | MGLSTAYSPV | MGLSTAYSPVGSHLAPAPLGHRRSAQLHRPRRALLATVRCSVDAAKQVQDGVATAEAPATRKDCFGVFCTTYDLKAEDKTKSWKKLVNIAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYPLLREVSIGIDPYEVFEDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASKNVKVLVVGNPCNTNALICLKNAPDIPAKNFHALTRLDENRAKCQLALKAGVFYDKVSNVTIWGNHSTTQVPDFLNAKIDGRPVKEVIKDTKWLEEEFTITVQKRGGALIQKWGRSS... | malate metabolic process chloroplast malate dehydrogenase (NADP+) activity Sorghum bicolor 3D-structure Chloroplast Disulfide bond NADP Oxidoreductase Plastid Transit peptide MGLSTAYSPV MGLSTAYSPVGSHLAPAPLGHRRSAQLHRPRRALLATVRCSVDAAKQVQDGVATAEAPATRKDCFGVFCTTYDLKAEDKTKSWKKLVNIAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALE... |
defense response to bacterium digestion killing of cells of another organism metabolic process | extracellular region | lysozyme activity | Ovis aries | Antimicrobial Bacteriolytic enzyme Digestion Disulfide bond Glycosidase Hydrolase Reference proteome Secreted Signal | MKALIILGLL | MKALIILGLLCLSVAVQGKVFERCELARTLKELGLDGYKGVSLANWLCLTKWESSYNTKATNYNPGSESTDYGIFQINSKWWCNDGKTPNAVDGCHVSCSELMENNIAKAVACAKHIVSEQGITAWVAWKSHCRDHDVSSYVEGCSL | defense response to bacterium digestion killing of cells of another organism metabolic process extracellular region lysozyme activity Ovis aries Antimicrobial Bacteriolytic enzyme Digestion Disulfide bond Glycosidase Hydrolase Reference proteome Secreted Signal MKALIILGLL MKALIILGLLCLSVAVQGKVFERCELARTLKELGLDGYKGVSLANWL... |
intra-Golgi vesicle-mediated transport intracellular protein transport positive regulation of TORC2 signaling protein localization to phagophore assembly site retrograde transport, endosome to Golgi retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum | cytosol; endomembrane system; endosome membrane; Golgi apparatus; Golgi membrane; nucleus; plasma membrane | GTP binding GTPase activity | Schizosaccharomyces pombe | Cell membrane Cytoplasm Endosome Golgi apparatus GTP-binding Lipoprotein Membrane Methylation Nucleotide-binding Nucleus Prenylation Protein transport Reference proteome Transport | MSENYSFSLR | MSENYSFSLRKFKLVFLGEQSVGKTSLITRFMYDQFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAIIVYDITNHNSFVNTEKWIEDVRAERGDDVIIVLVGNKTDLADKRQVTQEEGEKKAKELKIMHMETSAKAGHNVKLLFRKIAQMLPGMENVETQSTQMIDVSIQPNENESSCNC | intra-Golgi vesicle-mediated transport intracellular protein transport positive regulation of TORC2 signaling protein localization to phagophore assembly site retrograde transport, endosome to Golgi retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum cytosol; endomembrane system; endosome membrane; Go... |
exocytosis intracellular protein transport membrane addition at site of mitotic cytokinesis mitotic cytokinesis positive regulation of ascospore-type prospore membrane formation positive regulation of exocytosis protein localization to cell cortex of cell tip protein localization to meiotic spindle pole body vacuole fu... | cleavage furrow leading edge; cortical dynamic polarity patch; cytoplasm; cytosol; endosome membrane; Golgi apparatus; Golgi membrane; growing cell tip; meiotic spindle pole; meiotic spindle pole body; nucleus; prospore membrane; recycling endosome | GTP binding GTPase activity | Schizosaccharomyces pombe | Cell membrane Cytoplasm Endosome Golgi apparatus GTP-binding Lipoprotein Membrane Nucleotide-binding Nucleus Phosphoprotein Prenylation Protein transport Reference proteome Transport | MCQEDEYDYL | MCQEDEYDYLFKTVLIGDSGVGKSNLLMRFTRNEFNIESKSTIGVEFATRNIVLDNKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDITKQSSFDNVGRWLKELREHADSNIVIMLVGNKTDLLHLRAVSTEEAQAFAAENNLSFIETSAMDASNVEEAFQTVLTEIFRIVSNRSLEAGDDGVHPTAGQTLNIAPTMNDLNKKKSSSQCC | exocytosis intracellular protein transport membrane addition at site of mitotic cytokinesis mitotic cytokinesis positive regulation of ascospore-type prospore membrane formation positive regulation of exocytosis protein localization to cell cortex of cell tip protein localization to meiotic spindle pole body vacuole fu... |
glycogen biosynthetic process glycogen metabolic process response to glucose | cell cortex; cortical actin cytoskeleton; cytoplasm; cytoskeleton; cytosol | glucose binding glycogen (starch) synthase activity | Rattus norvegicus | Allosteric enzyme Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Transferase | MLRGRSLSVT | MLRGRSLSVTSLGGLPAWEAERLPVEDLLLFEVSWEVTNKVGGICTVIQSKAKTTANEWGENYFLIGPYFEHNVKTQVEPCEPANDAVRKAVDAMNKHGCQVHFGRWLIEGSPYVVLFDISSSVWNLDRWKGDFWEACGVGIPHDDREANDMLIFGSLTAWFLKEVTDHADGKHVIAQFHEWQAGTGLILSRARKLPIATIFTTHATLLGRYLCAANIDFYNQLDKFNIDKEAGERQIYHRYCMERASVHCAHVFTTVSEITAIEADHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHATYKARIQDFVRGHFYGHLDFDL... | glycogen biosynthetic process glycogen metabolic process response to glucose cell cortex; cortical actin cytoskeleton; cytoplasm; cytoskeleton; cytosol glucose binding glycogen (starch) synthase activity Rattus norvegicus Allosteric enzyme Glycogen biosynthesis Glycosyltransferase Phosphoprotein Reference proteome Tran... |
DNA recombination mRNA 3'-end processing mRNA export from nucleus positive regulation of transcription by RNA polymerase I positive regulation of transcription elongation by RNA polymerase I transcription elongation by RNA polymerase II transcription-coupled nucleotide-excision repair | Cdc73/Paf1 complex; chromosome, telomeric region; nucleoplasmic THO complex; THO complex part of transcription export complex; transcription export complex | molecular adaptor activity nucleic acid binding | Saccharomyces cerevisiae | 3D-structure Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSNTEELIQN | MSNTEELIQNSIGFLQKTFKALPVSFDSIRHEPLPSSMLHASVLNFEWEPLEKNISAIHDRDSLIDIILKRFIIDSMTNAIEDEEENNLEKGLLNSCIGLDFVYNSRFNRSNPASWGNTFFELFSTIIDLLNSPSTFLKFWPYAESRIEWFKMNTSVEPVSLGESNLISYKQPLYEKLRHWNDILAKLENNDILNTVKHYNMKYKLENFLSELLPINEESNFNRSASISALQESDNEWNRSARERESNRSSDVIFAADYNFVFYHLIICPIEFAFSDLEYKNDVDRSLSPLLDAILEIEENFYSKIKMNNRTRYSLEEAL... | DNA recombination mRNA 3'-end processing mRNA export from nucleus positive regulation of transcription by RNA polymerase I positive regulation of transcription elongation by RNA polymerase I transcription elongation by RNA polymerase II transcription-coupled nucleotide-excision repair Cdc73/Paf1 complex; chromosome, te... |
NADPH oxidation | endoplasmic reticulum membrane; membrane | flavin adenine dinucleotide binding hypotaurine dehydrogenase activity N,N-dimethylaniline monooxygenase activity NADP binding | Oryctolagus cuniculus | Acetylation Direct protein sequencing Endoplasmic reticulum FAD Flavoprotein Isopeptide bond Magnesium Membrane Microsome Monooxygenase NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix Ubl conjugation | MAKKVAVIGA | MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDGRASIYQSVITNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDFASSGQWEVVTQSNSKQQSAVFDAVMVCSGHHILPNIPLKSFPGIEKFKGQYFHSRQYKHPAGLEGKRILVIGIGNSASDIAVELSKKAAQVYISTRKGSWVMSRISEDGYPWDMVFHTRFSSMLRNVLPRMIVKWMMEQQMNRWFNHENYGLAPENKYLMKEPVLNDDLPSRILYGTIKVKRRVKELTESAAIFEDGTVEE... | NADPH oxidation endoplasmic reticulum membrane; membrane flavin adenine dinucleotide binding hypotaurine dehydrogenase activity N,N-dimethylaniline monooxygenase activity NADP binding Oryctolagus cuniculus Acetylation Direct protein sequencing Endoplasmic reticulum FAD Flavoprotein Isopeptide bond Magnesium Membrane Mi... |
taurine biosynthetic process | endoplasmic reticulum membrane | flavin adenine dinucleotide binding hypotaurine dehydrogenase activity N,N-dimethylaniline monooxygenase activity NADP binding trimethylamine monooxygenase activity | Oryctolagus cuniculus | Acetylation Direct protein sequencing Endoplasmic reticulum FAD Flavoprotein Membrane Monooxygenase NADP Oxidoreductase Reference proteome Transmembrane Transmembrane helix | MAKRVAIVGA | MAKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLDYLKMYADRFSLLKSIQFKTTVFSITKCQDFNVSGQWEVVTLHEGKQESAIFDAVMVCTGFLTNPHLPLGCFPGIKTFKGQYFHSRQYKHPDIFKDKRVLVVGMGNSGTDIAVEASHVAKKVFLSTTGGAWVISRVFDSGYPWDMVFTTRFQNFIRNSLPTPIVTWLVAKKMNSWFNHANYGLVPKDRIQLKEPVLNDELPGRIITGKVFIRPSIKEVKENSVVFGNAHNTP... | taurine biosynthetic process endoplasmic reticulum membrane flavin adenine dinucleotide binding hypotaurine dehydrogenase activity N,N-dimethylaniline monooxygenase activity NADP binding trimethylamine monooxygenase activity Oryctolagus cuniculus Acetylation Direct protein sequencing Endoplasmic reticulum FAD Flavoprot... |
acetoacetic acid metabolic process melanin biosynthetic process melanocyte differentiation melanosome organization positive regulation of melanin biosynthetic process | clathrin-coated endocytic vesicle membrane; cytoplasm; endosome membrane; intracellular vesicle; melanosome; melanosome membrane | metal ion binding oxidoreductase activity protein homodimerization activity tyrosinase activity | Homo sapiens | 3D-structure Albinism Copper Direct protein sequencing Disease variant Disulfide bond Glycoprotein Melanin biosynthesis Membrane Metal-binding Monooxygenase Oxidoreductase Reference proteome Signal Transmembrane Transmembrane helix Zinc | MSAPKLLSLG | MSAPKLLSLGCIFFPLLLFQQARAQFPRQCATVEALRSGMCCPDLSPVSGPGTDRCGSSSGRGRCEAVTADSRPHSPQYPHDGRDDREVWPLRFFNRTCHCNGNFSGHNCGTCRPGWRGAACDQRVLIVRRNLLDLSKEEKNHFVRALDMAKRTTHPLFVIATRRSEEILGPDGNTPQFENISIYNYFVWTHYYSVKKTFLGVGQESFGEVDFSHEGPAFLTWHRYHLLRLEKDMQEMLQEPSFSLPYWNFATGKNVCDICTDDLMGSRSNFDSTLISPNSVFSQWRVVCDSLEDYDTLGTLCNSTEDGPIRRNPAGNVA... | acetoacetic acid metabolic process melanin biosynthetic process melanocyte differentiation melanosome organization positive regulation of melanin biosynthetic process clathrin-coated endocytic vesicle membrane; cytoplasm; endosome membrane; intracellular vesicle; melanosome; melanosome membrane metal ion binding oxidor... |
monoatomic cation transmembrane transport synaptic transmission, cholinergic | acetylcholine-gated channel complex; neuron projection; postsynaptic membrane; synapse | acetylcholine-gated monoatomic cation-selective channel activity excitatory extracellular ligand-gated monoatomic ion channel activity transmembrane signaling receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Drosophila melanogaster | Cell membrane Disulfide bond Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MAPGCCTTRP | MAPGCCTTRPRPIALLAHIWRHCKPLCLLLVLLLLCETVQANPDAKRLYDDLLSNYNRLIRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYGGVTELYVPSEHIWLPDIVLYNNADGEYVVTTMTKAILHYTGKVVWTPPAIFKSSCEIDVRYFPFDQQTCFMKFGSWTYDGDQIDLKHISQKNDKDNKVEIGIDLREYYPSVEWDILGVPAERHEKYYPCCAEPYPDIFFNITLRRKTLFYTVNLIIPCVGISYLSVLVFYLPADSGEKIALCISILLSQTMFFLLISEIIPSTSLA... | monoatomic cation transmembrane transport synaptic transmission, cholinergic acetylcholine-gated channel complex; neuron projection; postsynaptic membrane; synapse acetylcholine-gated monoatomic cation-selective channel activity excitatory extracellular ligand-gated monoatomic ion channel activity transmembrane signali... |
gamma-aminobutyric acid catabolic process | cytosol; mitochondrion | 4-aminobutyrate transaminase activity 4-aminobutyrate:2-oxoglutarate transaminase activity pyridoxal phosphate binding | Saccharomyces cerevisiae | Aminotransferase Cytoplasm Pyridoxal phosphate Reference proteome Transferase | MSICEQYYPE | MSICEQYYPEEPTKPTVKTESIPGPESQKQLKELGEVFDTRPAYFLADYEKSLGNYITDVDGNTYLDLYAQISSIALGYNNPALIKAAQSPEMIRALVDRPALGNFPSKDLDKILKQILKSAPKGQDHVWSGLSGADANELAFKAAFIYYRAKQRGYDADFSEKENLSVMDNDAPGAPHLAVLSFKRAFHGRLFASGSTTCSKPIHKLDFPAFHWPHAEYPSYQYPLDENSDANRKEDDHCLAIVEELIKTWSIPVAALIIEPIQSEGGDNHASKYFLQKLRDITLKYNVVYIIDEVQTGVGATGKLWCHEYADIQPPVD... | gamma-aminobutyric acid catabolic process cytosol; mitochondrion 4-aminobutyrate transaminase activity 4-aminobutyrate:2-oxoglutarate transaminase activity pyridoxal phosphate binding Saccharomyces cerevisiae Aminotransferase Cytoplasm Pyridoxal phosphate Reference proteome Transferase MSICEQYYPE MSICEQYYPEEPTKPTVKTES... |
behavioral response to pain blastocyst development cellular response to amino acid stimulus cellular response to interferon-beta cellular response to lipopolysaccharide female pregnancy myoblast fusion positive regulation of cardiac muscle cell apoptotic process positive regulation of myoblast fusion positive regulatio... | calpain complex; chromatin; cortical actin cytoskeleton; cytoplasm; cytosol; dendrite; endoplasmic reticulum; external side of plasma membrane; extracellular exosome; focal adhesion; Golgi apparatus; lysosome; membrane raft; neuronal cell body; nucleus; perinuclear endoplasmic reticulum; plasma membrane; pseudopodium | calcium ion binding calcium-dependent cysteine-type endopeptidase activity cysteine-type peptidase activity cytoskeletal protein binding enzyme binding protein-containing complex binding | Homo sapiens | 3D-structure Acetylation Alternative splicing Calcium Cell membrane Cytoplasm Direct protein sequencing Hydrolase Membrane Metal-binding Protease Reference proteome Repeat Thiol protease | MAGIAAKLAK | MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHE... | behavioral response to pain blastocyst development cellular response to amino acid stimulus cellular response to interferon-beta cellular response to lipopolysaccharide female pregnancy myoblast fusion positive regulation of cardiac muscle cell apoptotic process positive regulation of myoblast fusion positive regulatio... |
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