Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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potassium ion transmembrane transport potassium ion transport protein homooligomerization | axon terminus; cytosol; intracellular membrane-bounded organelle; plasma membrane; potassium channel complex; voltage-gated potassium channel complex | delayed rectifier potassium channel activity voltage-gated potassium channel activity | Homo sapiens | Cell membrane Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MRSEKSLTLA | MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQE... | potassium ion transmembrane transport potassium ion transport protein homooligomerization axon terminus; cytosol; intracellular membrane-bounded organelle; plasma membrane; potassium channel complex; voltage-gated potassium channel complex delayed rectifier potassium channel activity voltage-gated potassium channel act... |
potassium ion transmembrane transport protein homooligomerization | axon; axon terminus; plasma membrane; potassium channel complex; voltage-gated potassium channel complex | delayed rectifier potassium channel activity | Rattus norvegicus | Cell membrane Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MRSEKSLTLA | MRSEKSLTLAAPGEVRGPEGEQQDAGEFQEAEGGGGCCSSERLVINISGLRYETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFMEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRADGRGGSNEGSGTRMSPASRGSHEEEDEDEDSYAFPGSIPSGGLGTGGTSSFSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIFPYFITLGTELVQRH... | potassium ion transmembrane transport protein homooligomerization axon; axon terminus; plasma membrane; potassium channel complex; voltage-gated potassium channel complex delayed rectifier potassium channel activity Rattus norvegicus Cell membrane Ion channel Ion transport Lipoprotein Membrane Palmitate Phosphoprotein ... |
cytoskeleton organization intermediate filament organization muscle contraction regulation of heart contraction skeletal muscle organ development | cardiac myofibril; cell-cell junction; cytosol; extracellular exosome; fascia adherens; intercalated disc; intermediate filament; intermediate filament cytoskeleton; neuromuscular junction; nucleus; sarcolemma; Z disc | cytoskeletal protein binding identical protein binding structural constituent of cytoskeleton | Homo sapiens | ADP-ribosylation Cardiomyopathy Cell membrane Coiled coil Cytoplasm Desmin-related myopathy Disease variant Intermediate filament Limb-girdle muscular dystrophy Membrane Methylation Muscle protein Myofibrillar myopathy Nucleus Phosphoprotein Reference proteome Ubl conjugation | MSQAYSSSQR | MSQAYSSSQRVSSYRRTFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQE... | cytoskeleton organization intermediate filament organization muscle contraction regulation of heart contraction skeletal muscle organ development cardiac myofibril; cell-cell junction; cytosol; extracellular exosome; fascia adherens; intercalated disc; intermediate filament; intermediate filament cytoskeleton; neuromus... |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Simian immunodeficiency virus | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by viru... | MGTKWSKSSL | MGTKWSKSSLVGWPEVRRRIREAPTAAEGVGEVSKDLERHGAITSRNTPETNQTLAWLEEMDNEEVGFPVRPQVPTRPMTYKAAFDLSHFLKEKGGLEGLVYSRRRQEILDLWVYHTQGFFPDWQNYTTGPGTRFPLCFGWCFKLVPLTEEQVEQANEGDNNCLLHPICQHGMEDEDKEVLVWRFDSRLALRHIAREQHPEYYKD | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membr... |
astrocyte differentiation axon choice point recognition axon regeneration cell fate commitment protein kinase C-activating G protein-coupled receptor signaling pathway radial glial cell differentiation regulation of filopodium assembly regulation of growth regulation of postsynaptic specialization assembly response to ... | cytoplasm; dendrite; filopodium membrane; GABA-ergic synapse; growth cone membrane; perikaryon; plasma membrane; postsynaptic density; presynapse | calmodulin binding lysophosphatidic acid binding phosphatidylinositol phosphate binding phosphatidylserine binding | Homo sapiens | Alternative splicing Calmodulin-binding Cell membrane Cell projection Cytoplasm Developmental protein Differentiation Growth regulation Lipoprotein Membrane Neurogenesis Palmitate Phosphoprotein Reference proteome Synapse | MLCCMRRTKQ | MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA | astrocyte differentiation axon choice point recognition axon regeneration cell fate commitment protein kinase C-activating G protein-coupled receptor signaling pathway radial glial cell differentiation regulation of filopodium assembly regulation of growth regulation of postsynaptic specialization assembly response to ... |
cell fate commitment negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription coactivator binding zinc ion binding | Gallus gallus | 3D-structure Acetylation Activator DNA-binding Metal-binding Nucleus Reference proteome Repeat Repressor Transcription Transcription regulation Zinc Zinc-finger | MEFVALGGPD | MEFVALGGPDAGSPTPFPDEAGAFLGLGGGERTEAGGLLASYPPSGRVSLVPWADTGTLGTPQWVPPATQMEPPHYLELLQPPRGSPPHPSSGPLLPLSSGPPPCEARECVNCGATATPLWRRDGTGHYLCNACGLYHRLNGQNRPLIRPKKRLLVSKRAGTVCSNCQTSTTTLWRRSPMGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKVSSKGKKRRPPGGGNPSATAGGGAPMGGGGDPSMPPPPPPPAAAPPQSDALYALGPVVLSGHFLPFGNSGGFFGGGAGGYTAPPGLSPQI | cell fate commitment negative regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription coactivator binding z... |
cellular response to oxidative stress glutathione metabolic process | cytoplasm; cytosol; mitochondrion; nucleus | disulfide oxidoreductase activity glutathione disulfide oxidoreductase activity glutathione peroxidase activity glutathione transferase activity | Saccharomyces cerevisiae | 3D-structure Alternative initiation Cytoplasm Direct protein sequencing Disulfide bond Electron transport Glutathionylation Mitochondrion Oxidoreductase Phosphoprotein Redox-active center Reference proteome Transferase Transit peptide Transport | METNFSFDSN | METNFSFDSNLIVIIIITLFATRIIAKRFLSTPKMVSQETVAHVKDLIGQKEVFVAAKTYCPYCKATLSTLFQELNVPKSKALVLELDEMSNGSEIQDALEEISGQKTVPNVYINGKHIGGNSDLETLKKNGKLAEILKPVFQ | cellular response to oxidative stress glutathione metabolic process cytoplasm; cytosol; mitochondrion; nucleus disulfide oxidoreductase activity glutathione disulfide oxidoreductase activity glutathione peroxidase activity glutathione transferase activity Saccharomyces cerevisiae 3D-structure Alternative initiation Cy... |
chaperone-mediated protein folding immune complex clearance intrinsic apoptotic signaling pathway negative regulation of amyloid fibril formation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of protein-containing complex assembly positive regulation of apopt... | chromaffin granule; cytoplasm; cytosol; extracellular space; intracellular membrane-bounded organelle; mitochondrial inner membrane; mitochondrion; nucleus; perinuclear endoplasmic reticulum lumen; perinuclear region of cytoplasm; spherical high-density lipoprotein particle | misfolded protein binding ubiquitin protein ligase binding unfolded protein binding | Bos taurus | Chaperone Cytoplasm Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Membrane Microsome Mitochondrion Nucleus Phosphoprotein Reference proteome Secreted Signal Ubl conjugation | MKTLLLLMGL | MKTLLLLMGLLLSWESGWAISDKELQEMSTEGSKYVNKEIKNALKEVKQIKTQIEQTNEERKLLLSSLEEAKKKKEDALNDTRDSENKLKASQGVCNETMTALWEECKPCLKQTCMKFYARVCRSGSGLVGHQLEEFLNQSSPFYFWINGDRIDSLMENDREQSHVMDVMEDSFTRASSIMDELFQDRFFLRRPQDTQYYSPFSSFPRGSLFFNPKSRFARNVMPFPLLEPFNFHDVFQPFYDMIHQAQQAMDAHLQRTPYHFPTMEFTENNDRTVCKEIRHNSTGCLRMKDQCEKCQEILEVDCSASNPTQTLLRQQLN... | chaperone-mediated protein folding immune complex clearance intrinsic apoptotic signaling pathway negative regulation of amyloid fibril formation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of protein-containing complex assembly positive regulation of apopt... |
polyamine metabolic process spermidine biosynthetic process spermine biosynthetic process | cytosol | adenosylmethionine decarboxylase activity identical protein binding putrescine binding | Homo sapiens | 3D-structure Alternative splicing Autocatalytic cleavage Decarboxylase Direct protein sequencing Lyase Phosphoprotein Polyamine biosynthesis Pyruvate Reference proteome S-adenosyl-L-methionine Schiff base Spermidine biosynthesis Zymogen | MEAAHFFEGT | MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNF... | polyamine metabolic process spermidine biosynthetic process spermine biosynthetic process cytosol adenosylmethionine decarboxylase activity identical protein binding putrescine binding Homo sapiens 3D-structure Alternative splicing Autocatalytic cleavage Decarboxylase Direct protein sequencing Lyase Phosphoprotein Poly... |
polyamine metabolic process S-adenosylmethionine metabolic process spermidine biosynthetic process spermine biosynthetic process | cytosol | adenosylmethionine decarboxylase activity identical protein binding putrescine binding | Rattus norvegicus | Autocatalytic cleavage Decarboxylase Lyase Phosphoprotein Polyamine biosynthesis Pyruvate Reference proteome S-adenosyl-L-methionine Schiff base Spermidine biosynthesis Zymogen | MEAAHFFEGT | MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDLPESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNF... | polyamine metabolic process S-adenosylmethionine metabolic process spermidine biosynthetic process spermine biosynthetic process cytosol adenosylmethionine decarboxylase activity identical protein binding putrescine binding Rattus norvegicus Autocatalytic cleavage Decarboxylase Lyase Phosphoprotein Polyamine biosynthes... |
carbohydrate phosphorylation glucose 6-phosphate metabolic process glucose import glucose metabolic process glycolytic process intracellular glucose homeostasis mannose metabolic process | cytosol; mitochondrion; plasma membrane | ATP binding fructokinase activity glucokinase activity glucose binding | Saccharomyces cerevisiae | 3D-structure Acetylation ATP-binding Glycolysis Kinase Nucleotide-binding Phosphoprotein Reference proteome Transferase | MSFDDLHKAT | MSFDDLHKATERAVIQAVDQICDDFEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNGTERGVLLAADLGGTNFRICSVNLHGDHTFSMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYHPDELAKGKDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSAQGMPMIKVVALTNDTVGTYLSHCYTSDNTDSMTSGEISEPVIGCIFGTGTNGCYMEEINKITKLPQELRDKLIKEGKTHMIINVEWGSFDNELKHLPTTKYDVVIDQKLSTNPGFH... | carbohydrate phosphorylation glucose 6-phosphate metabolic process glucose import glucose metabolic process glycolytic process intracellular glucose homeostasis mannose metabolic process cytosol; mitochondrion; plasma membrane ATP binding fructokinase activity glucokinase activity glucose binding Saccharomyces cerevisi... |
canonical glycolysis carbohydrate phosphorylation establishment of protein localization to mitochondrion fructose 6-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycolytic process inflammatory response innate immune response intracellular glucose homeostasis maintenance of... | caveola; cytosol; membrane raft; mitochondrial outer membrane; mitochondrion; protein-containing complex | ATP binding fructokinase activity glucokinase activity glucosamine kinase activity glucose binding hexokinase activity identical protein binding mannokinase activity peptidoglycan binding protein kinase activity protein-containing complex binding | Mus musculus | Allosteric enzyme Alternative initiation Alternative splicing ATP-binding Cytoplasm Direct protein sequencing Glycolysis Immunity Inflammatory response Innate immunity Kinase Membrane Mitochondrion Mitochondrion outer membrane Nucleotide-binding Phosphoprotein Reference proteome Repeat Transferase | MGWGAPLLSR | MGWGAPLLSRMLHGPGQAGETSPVPERQSGSENPASEDRRPLEKQCSHHLYTMGQNCQRGQAVDVEPKIRPPLTEEKIDKYLYAMRLSDEILIDILTRFKKEMKNGLSRDYNPTASVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKSQNVSMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAF... | canonical glycolysis carbohydrate phosphorylation establishment of protein localization to mitochondrion fructose 6-phosphate metabolic process glucose 6-phosphate metabolic process glucose metabolic process glycolytic process inflammatory response innate immune response intracellular glucose homeostasis maintenance of... |
glucose metabolic process glycolytic process | cytoplasm | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity NAD binding NADP binding | Thermotoga maritima | 3D-structure Cytoplasm Direct protein sequencing Glycolysis NAD Nucleotide-binding Oxidoreductase Reference proteome | MARVAINGFG | MARVAINGFGRIGRLVYRIIYERKNPDIEVVAINDLTDTKTLAHLLKYDSVHKKFPGKVEYTENSLIVDGKEIKVFAEPDPSKLPWKDLGVDFVIESTGVFRNREKAELHLQAGAKKVIITAPAKGEDITVVIGCNEDQLKPEHTIISCASCTTNSIAPIVKVLHEKFGIVSGMLTTVHSYTNDQRVLDLPHKDLRRARAAAVNIIPTTTGAAKAVALVVPEVKGKLDGMAIRVPTPDGSITDLTVLVEKETTVEEVNAVMKEATEGRLKGIIGYNDEPIVSSDIIGTTFSGIFDATITNVIGGKLVKVASWYDNEYGYS... | glucose metabolic process glycolytic process cytoplasm glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity NAD binding NADP binding Thermotoga maritima 3D-structure Cytoplasm Direct protein sequencing Glycolysis NAD Nucleotide-binding Oxidoreductase Reference proteome MARVAINGFG MARVAINGFGRIGRLVY... |
defense response | extracellular region | sodium channel inhibitor activity toxin activity | Leiurus hebraeus | 3D-structure Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin Voltage-gated sodium channel impairing toxin | MNHLVMISLA | MNHLVMISLALLLLLGVESVRDAYIAKNYNCVYECFRDAYCNELCTKNGASSGYCQWAGKYGNACWCYALPDNVPIRVPGKCHRK | defense response extracellular region sodium channel inhibitor activity toxin activity Leiurus hebraeus 3D-structure Direct protein sequencing Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin Voltage-gated sodium channel impairing toxin MNHLVMISLA MNHLVMISLALLLLLGVESVRDAYIAKNYNCVYECFRDAYCNEL... |
2-oxoglutarate metabolic process biosynthetic process glutamate metabolic process L-phenylalanine catabolic process response to dexamethasone response to mercury ion response to oxidative stress tyrosine catabolic process | cytosol | amino acid binding identical protein binding L-tyrosine:2-oxoglutarate aminotransferase activity pyridoxal phosphate binding | Homo sapiens | 3D-structure Acetylation Aminotransferase Disease variant Intellectual disability Palmoplantar keratoderma Phenylalanine catabolism Phosphoprotein Pyridoxal phosphate Reference proteome Transferase Tyrosine catabolism | MDPYMIQMSS | MDPYMIQMSSKGNLPSILDVHVNVGGRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIVDNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDGLVKLSQRILGPC... | 2-oxoglutarate metabolic process biosynthetic process glutamate metabolic process L-phenylalanine catabolic process response to dexamethasone response to mercury ion response to oxidative stress tyrosine catabolic process cytosol amino acid binding identical protein binding L-tyrosine:2-oxoglutarate aminotransferase ac... |
chemotaxis defense response to Gram-negative bacterium defense response to Gram-positive bacterium DNA geometric change DNA recombination DNA topological change double-strand break repair via nonhomologous end joining inflammatory response to antigenic stimulus innate immune response male gonad development negative reg... | chromatin; condensed chromosome; cytoplasm; extracellular space; nucleus; perinuclear region of cytoplasm | cis-regulatory region sequence-specific DNA binding DNA binding DNA binding, bending double-stranded DNA binding four-way junction DNA binding non-sequence-specific DNA binding, bending protein domain specific binding single-stranded DNA binding supercoiled DNA binding transcription factor binding | Sus scrofa | 3D-structure Acetylation Chemotaxis Chromosome Cytoplasm Disulfide bond DNA recombination DNA-binding Immunity Inflammatory response Innate immunity Nucleus Oxidation Phosphoprotein Reference proteome Repeat Secreted Transcription Transcription regulation | MGKGDPNKPR | MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKGEAGKKGPGRPTGSKKKNEPEDEEEEEEEEEDEDEEEEDEDEE | chemotaxis defense response to Gram-negative bacterium defense response to Gram-positive bacterium DNA geometric change DNA recombination DNA topological change double-strand break repair via nonhomologous end joining inflammatory response to antigenic stimulus innate immune response male gonad development negative reg... |
chloroplast organization leaf development | apoplast; chloroplast; chloroplast envelope; chloroplast nucleoid; chloroplast stroma; chloroplast thylakoid; chloroplast thylakoid membrane; nucleolus; nucleus; plastid | GTP binding GTPase activity mRNA binding translation elongation factor activity | Arabidopsis thaliana | Chloroplast Elongation factor GTP-binding Nucleotide-binding Phosphoprotein Plastid Protein biosynthesis Reference proteome Transit peptide | MAISAPAACS | MAISAPAACSSSSRILCSYSSPSPSLCPAISTSGKLKTLTLSSSFLPSYSLTTTSASQSTRRSFTVRAARGKFERKKPHVNIGTIGHVDHGKTTLTAALTMALASIGSSVAKKYDEIDAAPEERARGITINTATVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQTKEHILLAKQVGVPDMVVFLNKEDQVDDAELLELVELEVRELLSSYEFNGDDIPIISGSALLAVETLTENPKVKRGDNKWVDKIYELMDAVDDYIPIPQRQTELPFLLAVEDVFSITGRGTVATGRVERGTVKVGETV... | chloroplast organization leaf development apoplast; chloroplast; chloroplast envelope; chloroplast nucleoid; chloroplast stroma; chloroplast thylakoid; chloroplast thylakoid membrane; nucleolus; nucleus; plastid GTP binding GTPase activity mRNA binding translation elongation factor activity Arabidopsis thaliana Chlorop... |
canonical glycolysis gluconeogenesis glucose metabolic process glyceraldehyde-3-phosphate biosynthetic process glyceraldehyde-3-phosphate metabolic process glycerol catabolic process glycolytic process methylglyoxal biosynthetic process | cytosol | isomerase activity methylglyoxal synthase activity protein homodimerization activity triose-phosphate isomerase activity ubiquitin protein ligase binding | Mus musculus | Acetylation Alternative initiation Cytoplasm Direct protein sequencing Gluconeogenesis Glycolysis Isomerase Isopeptide bond Lyase Methylation Nitration Phosphoprotein Reference proteome Ubl conjugation | MAPTRKFFVG | MAPTRKFFVGGNWKMNGRKKCLGELICTLNAANVPAGTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDLGATWVVLGHSERRHVFGESDELIGQKVSHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVNDGVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDIINAKQ | canonical glycolysis gluconeogenesis glucose metabolic process glyceraldehyde-3-phosphate biosynthetic process glyceraldehyde-3-phosphate metabolic process glycerol catabolic process glycolytic process methylglyoxal biosynthetic process cytosol isomerase activity methylglyoxal synthase activity protein homodimerization... |
aromatic amino acid metabolic process bone remodeling circadian rhythm mammary gland alveolus development negative regulation of ossification platelet degranulation positive regulation of fat cell differentiation regulation of hemostasis response to immobilization stress serotonin biosynthetic process | cytosol; neuron projection | iron ion binding tryptophan 5-monooxygenase activity | Homo sapiens | 3D-structure Alternative splicing Iron Metal-binding Monooxygenase Oxidoreductase Phosphoprotein Reference proteome Serotonin biosynthesis Ubl conjugation | MIEDNKENKD | MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGL... | aromatic amino acid metabolic process bone remodeling circadian rhythm mammary gland alveolus development negative regulation of ossification platelet degranulation positive regulation of fat cell differentiation regulation of hemostasis response to immobilization stress serotonin biosynthetic process cytosol; neuron p... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 2 subtype A | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of host innate i... | MEPGRNQLLV | MEPGRNQLLVAILLTSACLIYCKQYVTVFYGIPAWRNASIPLFCATKNRDTWGTIQCLPDNDDYQEITLNVTEAFDAWDNTVTEQAIEDVWRLFETSIKPCVKLTPLCVAMNCNITSGTTATPSPPNITIIDENSTCIGDNNCTGLGKEEVVECEFNMTGLEQDKKRKYNDAWYSRDVVCDKTNGTGTCYMRHCNTSVIKESCDKHYWDAMKFRYCAPPGFALLRCNDTNYSGFEPKCSKVVAASCTRMMETQTSTWFGFNGTRAENRTYIYWHGKDNRTIISLNKYYNLTMHCKRPGNKTVVPITLMSGRRFHSRPVYN... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membra... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 2 subtype A | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral release from hos... | MGARNSVLRG | MGARNSVLRGKKADELEKVRLRPNGKKRYRLKHVVWAANELDRFGLAESLLESKEGCQKILKVLEPLVPTGSENLKSLFNTVCVIWCLHAEEKVKDTEEAKKLAQRHLVAETGTAEKMPNISRPTAPPSGKGGNFPVQQAGGNYIHVPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAADWDAQHPIPGPLPAGQLRDPRGSDIAGTTSTVDEQIQWMYRQPNPVPVGNIYRRWIQIGLQKCVRMYNPTNILDVKQGPKESFQSYVDRFYKSLRAEQTDPAVKNWMT... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 2 subtype A AIDS Capsid protein Host cell membrane Host cytoplasm Host e... |
acetyl-CoA biosynthetic process acetyl-CoA catabolic process adipose tissue development coenzyme A biosynthetic process coenzyme A metabolic process fatty acid beta-oxidation isoleucine catabolic process ketone body catabolic process liver development metanephric proximal convoluted tubule development propionyl-CoA bio... | endoplasmic reticulum; mitochondrial matrix; mitochondrion | acetyl-CoA C-acetyltransferase activity C-acetyltransferase activity cholesterol O-acyltransferase activity coenzyme A binding enzyme binding identical protein binding potassium ion binding | Rattus norvegicus | Acetylation Acyltransferase Direct protein sequencing Fatty acid metabolism Lipid metabolism Metal-binding Mitochondrion Phosphoprotein Potassium Reference proteome Transferase Transit peptide | MAALAVLHGV | MAALAVLHGVVRRPLLRGLLQEVRCLGRSYASKPTLNDVVIVSATRTPIGSFLGSLASQPATKLGTIAIQGAIEKAGIPKEEVKEVYMGNVIQGGEGQAPTRQATLGAGLPIATPCTTVNKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMSRGATPYGGVKLEDLIVKDGLTDVYNKIHMGNCAENTAKKLSISREEQDKYAIGSYTRSKEAWDAGKFANEITPITISVKGKPDVVVKEDEEYKRVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAAVVLMTAEAAQRLKVKPLARIAAFADAAVDPI... | acetyl-CoA biosynthetic process acetyl-CoA catabolic process adipose tissue development coenzyme A biosynthetic process coenzyme A metabolic process fatty acid beta-oxidation isoleucine catabolic process ketone body catabolic process liver development metanephric proximal convoluted tubule development propionyl-CoA bio... |
bone mineralization calcium ion homeostasis endocardial cell differentiation growth plate cartilage development positive regulation of calcium ion transport positive regulation of chondrocyte differentiation regulation of plasminogen activation transforming growth factor beta3 activation transforming growth factor beta... | basement membrane; calcium channel complex; collagen-containing extracellular matrix; cytoplasm; extracellular space; nucleus; plasma membrane; protein-containing complex; vesicle | calcium channel activity calcium ion binding calcium-dependent phospholipid binding cytoskeletal protein binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylserine binding phospholipase A2 inhibitor activity protease binding virion binding voltage-gated calcium channel activity involved in regulation of c... | Gallus gallus | 3D-structure Acetylation Annexin Basement membrane Calcium Calcium/phospholipid-binding Direct protein sequencing Extracellular matrix Phosphoprotein Reference proteome Repeat Secreted | MSTVHEILSK | MSTVHEILSKLSLEGDHSLPPSAYATVKAYSNFDADRDAAALEAAIKTKGVDEVTIINILTNRSNEQRQDIAFAYQRRTKKELSAALKSALSGHLEAVILGLLKTPSQYDASELKAAMKGLGTDEDTLIEIICSRTNQELNEINRVYREMYKTELEKDIISDTSGDFRKLMVALAKGKRCEDTSVIDYELIDQDARELYDAGVKRKGTDVPKWINIMTERSVPHLQKVFERYKSYSPYDMLESIKKEVKGDLENAFLNLVQCIQNKQLYFADRLYDSMKGKGTRDKVLIRIMVSRCEVDMLKIKSEFKRKYGKSLYYFIQ... | bone mineralization calcium ion homeostasis endocardial cell differentiation growth plate cartilage development positive regulation of calcium ion transport positive regulation of chondrocyte differentiation regulation of plasminogen activation transforming growth factor beta3 activation transforming growth factor beta... |
branch fusion, open tracheal system branching involved in open tracheal system development chitin-based cuticle development compound eye cone cell differentiation compound eye corneal lens morphogenesis dorsal appendage formation dorsal trunk growth, open tracheal system follicle cell of egg chamber development myoblas... | nucleus; polytene chromosome; transcription repressor complex | chromatin binding DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding promoter-specific chromatin binding protein homodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | 3D-structure Alternative splicing DNA-binding Isopeptide bond Metal-binding Nucleus Reference proteome Repeat Transcription Transcription regulation Ubl conjugation Zinc Zinc-finger | MKMASQRFCL | MKMASQRFCLRWNNHQSNLLSVFDQLLHAETFTDVTLAVEGQHLKAHKMVLSACSPYFNTLFVSHPEKHPIVILKDVPYSDMKSLLDFMYRGEVSVDQERLTAFLRVAESLRIKGLTEVNDDKPSPAAAAAGAGATGSESTATTPQLQRIQPYLVPQRNRSQAGGLLASAANAGNTPTLPVQPSLLSSALMPKRKRGRPRKLSGSSNGTGNDYDDFDRENMMNDSSDLGNGKMCNESYSGNDDGSDDNQPNAGHTDDLNESRDSLPSKRSKNSKDHRVVSHHEDNSTSDGNDSDGEGLDTSYMEPQLMLDEYDEPVEFKY... | branch fusion, open tracheal system branching involved in open tracheal system development chitin-based cuticle development compound eye cone cell differentiation compound eye corneal lens morphogenesis dorsal appendage formation dorsal trunk growth, open tracheal system follicle cell of egg chamber development myoblas... |
angiogenesis endothelial tube morphogenesis neural retina development neutrophil chemotaxis photoreceptor cell maintenance positive regulation of endothelial cell migration positive regulation of vascular endothelial growth factor production protein localization to plasma membrane | acrosomal membrane; basolateral plasma membrane; endoplasmic reticulum membrane; photoreceptor inner segment; photoreceptor outer segment; plasma membrane | signaling receptor activity | Gallus gallus | Alternative splicing Angiogenesis Cell membrane Cell projection Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Immunoglobulin domain Membrane Receptor Reference proteome Signal Transmembrane Transmembrane helix | MAAGADVPCA | MAAGADVPCAVLALLVLGSLAAGGDATAGFIKSPLSQRRLTQDSVELHCEAVGSPIPEIQWWFEGNEPNETSAQLWDGAWQDRVQINATYNLHSTSTIYIANLTSDDSGTYECRASNDPDRNHLSKSPKVKWIRSQANVLVIERPVITGQYSSSADKVVLSCNISAPPTLIKGHKWMLGDKVLKTDESDASSYISYTIEGKVEDHSGVYECIYNTNPVAKGNVSIEVEPQVVAYKKSEHGNEGDVGVLTCKSPSYPPVDHWAWYKSGQTVPLESSAGIYNISRTGNKTELRILKLNIEQDMGDYSCNGTNMKGSGSATVN... | angiogenesis endothelial tube morphogenesis neural retina development neutrophil chemotaxis photoreceptor cell maintenance positive regulation of endothelial cell migration positive regulation of vascular endothelial growth factor production protein localization to plasma membrane acrosomal membrane; basolateral plasma... |
cellular hyperosmotic response cellular response to glucose starvation cellular response to mechanical stimulus central nervous system development cerebral cortex development dehydroascorbic acid transport female pregnancy glucose import glucose import across plasma membrane glucose transmembrane transport long-chain f... | apical plasma membrane; basolateral plasma membrane; caveola; cell-cell junction; cortical actin cytoskeleton; cytoplasm; cytosol; female germ cell nucleus; female pronucleus; glucose transporter complex; Golgi membrane; intercalated disc; membrane; membrane raft; midbody; photoreceptor inner segment; plasma membrane; ... | D-glucose transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity glucose transmembrane transporter activity identical protein binding kinase binding long-chain fatty acid transporter activity protein self-association xenobiotic transmembrane transporter activity | Mus musculus | Acetylation Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Sugar transport Transmembrane Transmembrane helix Transport | MDPSSKKVTG | MDPSSKKVTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWNHRYGEPIPSTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVAAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAF... | cellular hyperosmotic response cellular response to glucose starvation cellular response to mechanical stimulus central nervous system development cerebral cortex development dehydroascorbic acid transport female pregnancy glucose import glucose import across plasma membrane glucose transmembrane transport long-chain f... |
cell adhesion detection of light stimulus involved in visual perception photoreceptor cell outer segment organization protein heterooligomerization protein homooligomerization protein localization to plasma membrane protein maturation protein polymerization regulation of membrane tubulation retina development in camera... | cytoplasm; membrane; photoreceptor inner segment; photoreceptor outer segment; protein-containing complex | identical protein binding protein homodimerization activity | Bos taurus | Cell adhesion Cell projection Direct protein sequencing Disulfide bond Glycoprotein Membrane Reference proteome Sensory transduction Transmembrane Transmembrane helix Vision | MALLKVKFDQ | MALLKVKFDQKKRVKLAQGLWLMNWFSVLAGIIIFGLGLFLKIELRKRSDVMNNSESHFVPNSLIGVGVLSCVFNSLAGKICYDALDPAKYAKWKPWLKPYLAVCVLFNVVLFLVALCCFLLRGSLESTLAHGLKNGMKFYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPNSPRPCIQYQLTNNSAHYSYDHQTEELNLWLRGCRAALLSYYSNLMNTTGAVTLLVWLFEVTITVGLRYLHTALEGMANPEDPECESEGWLLEKSVPETWKAFL... | cell adhesion detection of light stimulus involved in visual perception photoreceptor cell outer segment organization protein heterooligomerization protein homooligomerization protein localization to plasma membrane protein maturation protein polymerization regulation of membrane tubulation retina development in camera... |
fibrinolysis hemostasis proteolysis | cell outer membrane | aspartic-type endopeptidase activity | Yersinia pestis | 3D-structure Aspartyl protease Blood coagulation Cell outer membrane Fibrinolysis Hemostasis Hydrolase Membrane Plasmid Protease Reference proteome Signal Transmembrane Transmembrane beta strand | MKKSSIVATI | MKKSSIVATIITILSGSANAASSQLIPNISPDSFTVAASTGMLSGKSHEMLYDAETGRKISQLDWKIKNVAILKGDISWDPYSFLTLNARGWTSLASGSGNMDDYDWMNENQSEWTDHSSHPATNVNHANEYDLNVKGWLLQDENYKAGITAGYQETRFSWTATGGSYSYNNGAYTGNFPKGVRVIGYNQRFSMPYIGLAGQYRINDFELNALFKFSDWVRAHDNDEHYMRDLTFREKTSGSRYYGTVINAGYYVTPNAKVFAEFTYSKYDEGKGGTQTIDKNSGDSVSIGGDAAGISNKNYTVTAGLQYRF | fibrinolysis hemostasis proteolysis cell outer membrane aspartic-type endopeptidase activity Yersinia pestis3D-structure Aspartyl protease Blood coagulation Cell outer membrane Fibrinolysis Hemostasis Hydrolase Membrane Plasmid Protease Reference proteome Signal Transmembrane Transmembrane beta strand MKKSSIVATI MKKSSI... |
de novo' CTP biosynthetic process B cell proliferation CTP biosynthetic process glutamine metabolic process nucleobase-containing compound metabolic process pyrimidine nucleobase biosynthetic process response to xenobiotic stimulus T cell proliferation | cytoophidium; cytoplasm; cytosol; membrane | ATP binding CTP synthase activity identical protein binding | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Cytoplasm Glutamine amidotransferase Immunity Ligase Nucleotide-binding Phosphoprotein Pyrimidine biosynthesis Reference proteome | MKYILVTGGV | MKYILVTGGVISGIGKGIIASSVGTILKSCGLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQYVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGLEPQVCVIELGGTVGDIESMPFIEAFRQFQFKVKRENFCNIHVSLVPQPSSTGEQKTKPTQNSVRELRGLGLSPDLVVCRCSNPLDTSVKEKISMFCHVEPEQVICVHDVSSIYRVPLLLEEQGVVDYFLRRLDLPIERQPRKMLMKWKEMADRYDRLLETCSIALVGKYTKFSDSYASVIKA... | de novo' CTP biosynthetic process B cell proliferation CTP biosynthetic process glutamine metabolic process nucleobase-containing compound metabolic process pyrimidine nucleobase biosynthetic process response to xenobiotic stimulus T cell proliferation cytoophidium; cytoplasm; cytosol; membrane ATP binding CTP synthase... |
cell differentiation flower development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Arabidopsis thaliana | Activator Alternative splicing Coiled coil Developmental protein Differentiation DNA-binding Flowering Nucleus Reference proteome Transcription Transcription regulation | MAYQSELGGD | MAYQSELGGDSSPLRKSGRGKIEIKRIENTTNRQVTFCKRRNGLLKKAYELSVLCDAEVALIVFSSRGRLYEYSNNSVKGTIERYKKAISDNSNTGSVAEINAQYYQQESAKLRQQIISIQNSNRQLMGETIGSMSPKELRNLEGRLERSITRIRSKKNELLFSEIDYMQKREVDLHNDNQILRAKIAENERNNPSISLMPGGSNYEQLMPPPQTQSQPFDSRNYFQVAALQPNNHHYSSAGRQDQTALQLV | cell differentiation flower development positive regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II nucleus DNA-binding transcription factor activity, RNA polymerase II-specific protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA bin... |
alternative mRNA splicing, via spliceosome androgen receptor signaling pathway BMP signaling pathway epithelial to mesenchymal transition intracellular estrogen receptor signaling pathway intrinsic apoptotic signaling pathway by p53 class mediator miRNA transcription mRNA splicing, via spliceosome mRNA transcription my... | catalytic step 2 spliceosome; cytoplasm; cytosol; extracellular exosome; membrane; nuclear speck; nucleolus; nucleoplasm; nucleus; ribonucleoprotein complex | ATP binding ATP hydrolysis activity calcium-dependent protein binding calmodulin binding enzyme binding MH2 domain binding mRNA 3'-UTR binding nuclear androgen receptor binding pre-mRNA binding primary miRNA binding promoter-specific chromatin binding R-SMAD binding ribonucleoprotein complex binding RNA binding RNA hel... | Homo sapiens | 3D-structure Acetylation Alternative splicing ATP-binding Biological rhythms Cytoplasm Helicase Hydrolase Isopeptide bond mRNA processing mRNA splicing Nucleotide-binding Nucleus Phosphoprotein Reference proteome RNA-binding Spliceosome Transcription Transcription regulation Ubl conjugation | MSGYSSDRDR | MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVC... | alternative mRNA splicing, via spliceosome androgen receptor signaling pathway BMP signaling pathway epithelial to mesenchymal transition intracellular estrogen receptor signaling pathway intrinsic apoptotic signaling pathway by p53 class mediator miRNA transcription mRNA splicing, via spliceosome mRNA transcription my... |
cysteine biosynthetic process hydrogen sulfide biosynthetic process sulfate assimilation | sulfite reductase complex (NADPH) | 4 iron, 4 sulfur cluster binding heme binding metal ion binding NADP binding sulfite reductase (ferredoxin) activity sulfite reductase (NADPH) activity sulfite reductase activity | Escherichia coli | 3D-structure 4Fe-4S Amino-acid biosynthesis Cysteine biosynthesis Direct protein sequencing Heme Iron Iron-sulfur Metal-binding NADP Oxidoreductase Reference proteome | MSEKHPGPLV | MSEKHPGPLVVEGKLTDAERMKHESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFK... | cysteine biosynthetic process hydrogen sulfide biosynthetic process sulfate assimilation sulfite reductase complex (NADPH) 4 iron, 4 sulfur cluster binding heme binding metal ion binding NADP binding sulfite reductase (ferredoxin) activity sulfite reductase (NADPH) activity sulfite reductase activity Escherichia coli 3... |
hydrogen sulfide biosynthetic process sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) sulfur compound metabolic process | cytoplasm | phosphoadenylyl-sulfate reductase (thioredoxin) activity | Escherichia coli | 3D-structure Cytoplasm Direct protein sequencing Oxidoreductase Reference proteome | MSKLDLNALN | MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG | hydrogen sulfide biosynthetic process sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) sulfur compound metabolic process cytoplasm phosphoadenylyl-sulfate reductase (thioredoxin) activity Escherichia coli 3D-structure Cytoplasm Direct protein sequencing Oxidored... |
canonical glycolysis fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process glycolytic process negative regulation of insulin secretion response to glucose | 6-phosphofructokinase complex; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; secretory granule lumen | 6-phosphofructokinase activity AMP binding ATP binding fructose binding fructose-6-phosphate binding identical protein binding kinase binding metal ion binding monosaccharide binding | Homo sapiens | 3D-structure Acetylation Allosteric enzyme Alternative splicing ATP-binding Cytoplasm Direct protein sequencing Glycolysis Glycoprotein Kinase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Transferase | MAAVDLEKLR | MAAVDLEKLRASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEA... | canonical glycolysis fructose 1,6-bisphosphate metabolic process fructose 6-phosphate metabolic process glycolytic process negative regulation of insulin secretion response to glucose 6-phosphofructokinase complex; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; secretory g... |
cell division division septum assembly FtsZ-dependent cytokinesis protein polymerization | cell division site; cell septum; cytoplasm | GTP binding GTPase activity identical protein binding | Bacillus subtilis | 3D-structure Cell cycle Cell division Cytoplasm GTP-binding Nucleotide-binding Reference proteome Septation | MLEFETNIDG | MLEFETNIDGLASIKVIGVGGGGNNAVNRMIENEVQGVEYIAVNTDAQALNLSKAEVKMQIGAKLTRGLGAGANPEVGKKAAEESKEQIEEALKGADMVFVTAGMGGGTGTGAAPVIAQIAKDLGALTVGVVTRPFTFEGRKRQLQAAGGISAMKEAVDTLIVIPNDRILEIVDKNTPMLEAFREADNVLRQGVQGISDLIATPGLINLDFADVKTIMSNKGSALMGIGIATGENRAAEAAKKAISSPLLEAAIDGAQGVLMNITGGTNLSLYEVQEAADIVASASDQDVNMIFGSVINENLKDEIVVTVIATGFIEQEK... | cell division division septum assembly FtsZ-dependent cytokinesis protein polymerization cell division site; cell septum; cytoplasm GTP binding GTPase activity identical protein binding Bacillus subtilis 3D-structure Cell cycle Cell division Cytoplasm GTP-binding Nucleotide-binding Reference proteome Septation MLEFETNI... |
clathrin-dependent endocytosis desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor internalization negative regulation of Notch signaling pathway positive regulation of ERK1 and ERK2 cascade positive regulation of protein phosphorylation positive regulation of receptor internaliza... | clathrin coat of coated pit; cytoplasm; cytoplasmic vesicle; cytosol; nucleus; plasma membrane; pseudopodium | acetylcholine receptor binding AP-2 adaptor complex binding clathrin binding clathrin heavy chain binding G protein-coupled receptor binding inositol hexakisphosphate binding molecular adaptor activity phosphatidylinositol-3,4,5-trisphosphate binding small molecule binding | Bos taurus | 3D-structure Alternative splicing Cell membrane Cell projection Coated pit Cytoplasm Cytoplasmic vesicle Membrane Nucleus Phosphoprotein Protein transport Reference proteome Signal transduction inhibitor Transcription Transcription regulation Transport Ubl conjugation | MGDKGTRVFK | MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVEPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVS... | clathrin-dependent endocytosis desensitization of G protein-coupled receptor signaling pathway G protein-coupled receptor internalization negative regulation of Notch signaling pathway positive regulation of ERK1 and ERK2 cascade positive regulation of protein phosphorylation positive regulation of receptor internaliza... |
DNA-templated transcription initiation transcription initiation at RNA polymerase I promoter transcription initiation at RNA polymerase II promoter transcription initiation at RNA polymerase III promoter | nucleus; RNA polymerase I transcription regulator complex; transcription factor TFIID complex; transcription factor TFIIIB complex | RNA polymerase I general transcription initiation factor activity RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II general transcription initiation factor activity RNA polymerase III general transcription initiation factor activity RNA polymerase III type 3 promoter sequence-specific DNA ... | Schizosaccharomyces pombe | DNA-binding Nucleus Reference proteome Repeat Transcription | MDFALPTTAS | MDFALPTTASQASAFMNNSSLTFPVLPNANNEATNETADSGDAEVSKNEGVSGIVPTLQNIVATVNLDCRLDLKTIALHARNAEYNPKRFAAVIMRIREPKSTALIFASGKMVVLGGKSEDDSKLASRKYARIIQKLGFNAKFTDFKIQNIVGSCDVKFPIRLEGLAYSHGTFSSYEPELFPGLIYRMVKPKVVLLIFVSGKIVLTGAKVREEIYQAFEAIYPVLSEFRKH | DNA-templated transcription initiation transcription initiation at RNA polymerase I promoter transcription initiation at RNA polymerase II promoter transcription initiation at RNA polymerase III promoter nucleus; RNA polymerase I transcription regulator complex; transcription factor TFIID complex; transcription factor ... |
binding of sperm to zona pellucida chaperone cofactor-dependent protein refolding negative regulation of apoptotic process positive regulation of microtubule nucleation positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein folding protein refolding regulation of mitotic spindle assemb... | aggresome; apical plasma membrane; basolateral plasma membrane; cell body; centriole; centrosome; cytoplasm; cytosol; inclusion body; membrane raft; mitochondrial matrix; mitochondrion; nuclear speck; nucleus; perinuclear region of cytoplasm; protein-containing complex; ribonucleoprotein complex; zona pellucida recepto... | ATP binding ATP hydrolysis activity ATP-dependent protein disaggregase activity ATP-dependent protein folding chaperone C3HC4-type RING finger domain binding enzyme binding G protein-coupled receptor binding heat shock protein binding histone deacetylase binding NF-kappaB binding protease binding protein folding chaper... | Mus musculus | Acetylation ATP-binding Chaperone Cytoplasm Cytoskeleton Methylation Nucleotide-binding Phosphoprotein Reference proteome Stress response | MAKNTAIGID | MAKNTAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDAVVQSDMKHWPFQVVNDGDKPKVQVNYKGESRSFFPEEISSMVLTKMKEIAEAYLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRGTLEPVEKA... | binding of sperm to zona pellucida chaperone cofactor-dependent protein refolding negative regulation of apoptotic process positive regulation of microtubule nucleation positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein folding protein refolding regulation of mitotic spindle assemb... |
axon ensheathment glial cell migration Malpighian tubule morphogenesis mRNA splicing, via spliceosome oenocyte development regulation of alternative mRNA splicing, via spliceosome spliceosomal complex assembly | catalytic step 2 spliceosome; cytosol; nuclear speck; nucleus; post-mRNA release spliceosomal complex; precatalytic spliceosome; Prp19 complex; U2-type catalytic step 2 spliceosome | RNA binding | Drosophila melanogaster | Developmental protein Differentiation mRNA processing mRNA splicing Neurogenesis Nucleus Reference proteome Repeat | MERPQKMPKV | MERPQKMPKVAKVKNKAPAEVQITAEQLLREAKERDLEILPPPPKQKISDPAELADYQQRKRKTFEDNLRKNRMVVSHWIKYAQWEEQQQEIQRARSIWERALDNEHRNVTLWLKYAEMEMKNKQVNHARNLWDRAVTIMPRVNQFWYKYTYMEEMLENVAGARQVFERWMEWQPEEQAWQTYVNFELRYKEIDRAREIYERFVYVHPDVKNWIKFARFEESHGFIHGSRRVFERAVEFFGDDYIEERLFIAFARFEEGQKEHDRARIIYKYALDHLPKDRTQELFKAYTKHEKKYGDRAGIEDVIVSKRKYQYEQEVAA... | axon ensheathment glial cell migration Malpighian tubule morphogenesis mRNA splicing, via spliceosome oenocyte development regulation of alternative mRNA splicing, via spliceosome spliceosomal complex assembly catalytic step 2 spliceosome; cytosol; nuclear speck; nucleus; post-mRNA release spliceosomal complex; precata... |
DNA recombination DNA replication DNA replication initiation DNA replication, synthesis of RNA primer DNA unwinding involved in DNA replication DNA-templated DNA replication double-strand break repair plasmid maintenance replication fork processing response to antibiotic response to gamma radiation | DnaB-DnaC-DnaT-PriA-PriB complex; DnaB-DnaC-DnaT-PriA-PriC complex; primosome complex | 3'-5' DNA helicase activity ATP binding DNA binding helicase activity hydrolase activity zinc ion binding | Escherichia coli | 3D-structure ATP-binding Direct protein sequencing DNA replication DNA-binding Helicase Hydrolase Metal-binding Nucleotide-binding Primosome Reference proteome Zinc Zinc-finger | MPVAHVALPV | MPVAHVALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIGIVVSVSDASELPLNELKAVVEVLDSEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPILLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEFNDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAVGAIHSAADTFSAWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVID... | DNA recombination DNA replication DNA replication initiation DNA replication, synthesis of RNA primer DNA unwinding involved in DNA replication DNA-templated DNA replication double-strand break repair plasmid maintenance replication fork processing response to antibiotic response to gamma radiation DnaB-DnaC-DnaT-PriA-... |
termination of RNA polymerase III transcription transcription by RNA polymerase III transcription initiation at RNA polymerase III promoter tRNA transcription by RNA polymerase III | nucleoplasm; nucleus; RNA polymerase III complex | DNA binding nucleotidyltransferase activity | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing DNA-binding DNA-directed RNA polymerase Nucleotidyltransferase Nucleus Phosphoprotein Reference proteome Transcription Transferase | MSSYRGGSRG | MSSYRGGSRGGGSNYMSNLPFGLGYGDVGKNHITEFPSIPLPINGPITNKERSLAVKYINFGKTVKDGPFYTGSMSLIIDQQENSKSGKRKPNIILDEDDTNDGIERYSDKYLKKRKIGISIDDHPYNLNLFPNELYNVMGINKKKLLAISKFNNADDVFTGTGLQDENIGLSMLAKLKELAEDVDDASTGDGAAKGSKTGEGEDDDLADDDFEEDEDEEDDDDYNAEKYFNNGDDDDYGDEEDPNEEAAF | termination of RNA polymerase III transcription transcription by RNA polymerase III transcription initiation at RNA polymerase III promoter tRNA transcription by RNA polymerase III nucleoplasm; nucleus; RNA polymerase III complex DNA binding nucleotidyltransferase activity Saccharomyces cerevisiae 3D-structure Direct ... |
clathrin coat assembly clathrin-dependent endocytosis endocytosis intracellular protein transport positive regulation of endocytosis protein-containing complex assembly | clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin complex; clathrin vesicle coat; plasma membrane; trans-Golgi network | calmodulin binding clathrin heavy chain binding structural molecule activity | Saccharomyces cerevisiae | Calcium Calmodulin-binding Coated pit Coiled coil Cytoplasmic vesicle Direct protein sequencing Membrane Phosphoprotein Reference proteome | MSEKFPPLED | MSEKFPPLEDQNIDFTPNDKKDDDTDFLKREAEILGDEFKTEQDDILETEASPAKDDDEIRDFEEQFPDINSANGAVSSDQNGSATVSSGNDNGEADDDFSTFEGANQSTESVKEDRSEVVDQWKQRRAVEIHEKDLKDEELKKELQDEAIKHIDDFYDSYNKKKEQQLEDAAKEAEAFLKKRDEFFGQDNTTWDRALQLINQDDADIIGGRDRSKLKEILLRLKGNAKAPGA | clathrin coat assembly clathrin-dependent endocytosis endocytosis intracellular protein transport positive regulation of endocytosis protein-containing complex assembly clathrin coat of coated pit; clathrin coat of trans-Golgi network vesicle; clathrin complex; clathrin vesicle coat; plasma membrane; trans-Golgi networ... |
cellular defense response galactolipid catabolic process intestinal lipid catabolic process phosphatidylcholine catabolic process phospholipid catabolic process phospholipid metabolic process response to bacterium triglyceride catabolic process | extracellular space; neuron projection; zymogen granule membrane | 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity acylglycerol lipase activity calcium ion binding galactolipase activity lipase activity phospholipase activity triglyceride lipase activity | Mus musculus | Calcium Cell projection Cytoplasmic vesicle Disulfide bond Glycoprotein Hydrolase Lipid degradation Lipid metabolism Membrane Metal-binding Reference proteome Secreted Signal | MPMDVRGCLF | MPMDVRGCLFPSVQMLLCWLVSLLLATVGGKEVCYGHLGCFSNDKPWAGMIQRPSKIFPWSPEDIDTRFLLYTNENPNNYQIISATDPATINASNFQLDRKTRFIIHGFIDKGEEGWLLDMCKKMFQVEKVNCICVDWKRGSRTEYTQASYNTRVVGAEIAFLVQVLSTEMGYSPENVHLIGHSLGSHVAGEAGRRLEGHVGRITGLDPAEPCFQGLPEEVRLDPSDAMFVDVIHTDSAPIIPYLGFGMSQKVGHLDFFPNGGKEMPGCQKNILSTIVDINGIWEGTRNFAACNHLRSYKYYASSILNPDGFLGYPCSSY... | cellular defense response galactolipid catabolic process intestinal lipid catabolic process phosphatidylcholine catabolic process phospholipid catabolic process phospholipid metabolic process response to bacterium triglyceride catabolic process extracellular space; neuron projection; zymogen granule membrane 1-18:1-2-1... |
defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium killing of cells of another organism metabolic process | endoplasmic reticulum lumen; extracellular space; Golgi cis cisterna; Golgi stack; microvillus; rough endoplasmic reticulum lumen; secretory granule; trans-Golgi network transport vesicle | hydrolase activity, acting on glycosyl bonds identical protein binding lysozyme activity | Mus musculus | Antimicrobial Bacteriolytic enzyme Direct protein sequencing Disulfide bond Glycosidase Hydrolase Reference proteome Secreted Signal | MKALLTLGLL | MKALLTLGLLLLSVTAQAKVYNRCELARILKRNGMDGYRGVKLADWVCLAQHESNYNTRATNYNRGDRSTDYGIFQINSRYWCNDGKTPRSKNACGINCSALLQDDITAAIQCAKRVVRDPQGIRAWVAWRTQCQNRDLSQYIRNCGV | defense response to bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium killing of cells of another organism metabolic process endoplasmic reticulum lumen; extracellular space; Golgi cis cisterna; Golgi stack; microvillus; rough endoplasmic reticulum lumen; secretory granul... |
CDP-choline pathway | endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; mitochondrial outer membrane | diacylglycerol cholinephosphotransferase activity metal ion binding | Saccharomyces cerevisiae | Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Magnesium Membrane Metal-binding Microsome Mitochondrion Mitochondrion outer membrane Phospholipid biosynthesis Phospholipid metabolism Reference proteome Transferase Transmembrane Transmembrane helix | MGFFIPQSSL | MGFFIPQSSLGNLKLYKYQSDDRSFLSNHVLRPFWRKFATIFPLWMAPNLVTLLGFCFIIFNVLTTLYYDPYFDQESPRWTYFSYAIGLFLYQTFDACDGMHARRTGQQGPLGELFDHCIDSINTTLSMIPVCSMTGMGYTYMTIFSQFAILCSFYLSTWEEYHTHKLYLAEFCGPVEGIIVLCISFIAVGIYGPQTIWHTKVAQFSWQDFVFDVETVHLMYAFCTGALIFNIVTAHTNVVRYYESQSTKSATPSKTAENISKAVNGLLPFFAYFSSIFTLVLIQPSFISLALILSIGFSVAFVVGRMIIAHLTMQPFPM... | CDP-choline pathway endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; mitochondrial outer membrane diacylglycerol cholinephosphotransferase activity metal ion binding Saccharomyces cerevisiae Endoplasmic reticulum Lipid biosynthesis Lipid metabolism Magnesium Membrane Metal-binding Microsome Mito... |
ganglioside catabolic process glycosphingolipid catabolic process learning or memory lipid storage lipid transport maintenance of location in cell neuromuscular process controlling balance oligosaccharide catabolic process | apical plasma membrane; azurophil granule lumen; basolateral plasma membrane; cytoplasmic side of plasma membrane; cytosol; extracellular exosome; extracellular region; intracellular membrane-bounded organelle; lysosomal lumen | beta-N-acetylgalactosaminidase activity lipid transporter activity phospholipase activator activity sphingolipid activator protein activity | Homo sapiens | 3D-structure Direct protein sequencing Disease variant Disulfide bond Gangliosidosis Glycoprotein Hydrolase Lipid metabolism Lysosome Reference proteome Signal Sphingolipid metabolism | MQSLMQAPLL | MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIIVPGNVTLSVMGSTSVPLSSPLKVDLVLEKEVAGLWIKIPCTDYIGSCTFEHFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI | ganglioside catabolic process glycosphingolipid catabolic process learning or memory lipid storage lipid transport maintenance of location in cell neuromuscular process controlling balance oligosaccharide catabolic process apical plasma membrane; azurophil granule lumen; basolateral plasma membrane; cytoplasmic side of... |
DNA damage response DNA replication DNA-templated DNA replication eggshell chorion gene amplification leading strand elongation mismatch repair mitotic spindle organization nucleotide-excision repair positive regulation of DNA repair positive regulation of DNA replication response to hydrogen peroxide response to methy... | chromatin; cytoplasm; nuclear replication fork; nucleus; PCNA complex | chromatin binding DNA binding DNA polymerase processivity factor activity | Drosophila melanogaster | 3D-structure Chromosome Cytoplasm Direct protein sequencing DNA replication DNA-binding Nucleus Reference proteome | MFEARLGQAT | MFEARLGQATILKKILDAIKDLLNEATFDCSDSGIQLQAMDNSHVSLVSLTLRSDGFDKFRCDRNLSMGMNLGSMAKILKCANNEDNVTMKAQDNADTVTIMFESANQEKVSDYEMKLMNLDQEHLGIPETDFSCVVRMPAMEFARICRDLAQFSESVVICCTKEGVKFSASGDVGTANIKLAQTGSVDKEEEAVIIEMQEPVTLTFACRYLNAFTKATPLSTQVQLSMCADVPLVVEYAIKDLGHIRYYLAPKIEDNET | DNA damage response DNA replication DNA-templated DNA replication eggshell chorion gene amplification leading strand elongation mismatch repair mitotic spindle organization nucleotide-excision repair positive regulation of DNA repair positive regulation of DNA replication response to hydrogen peroxide response to methy... |
base-excision repair, gap-filling cellular response to hydrogen peroxide cellular response to UV cellular response to xenobiotic stimulus epithelial cell differentiation estrous cycle heart development leading strand elongation liver regeneration mismatch repair mitotic telomere maintenance via semi-conservative replic... | centrosome; chromatin; cyclin-dependent protein kinase holoenzyme complex; male germ cell nucleus; nuclear body; nuclear lamina; nuclear replication fork; nucleoplasm; nucleus; PCNA complex; PCNA-p21 complex; replication fork | chromatin binding damaged DNA binding dinucleotide insertion or deletion binding DNA polymerase binding DNA polymerase processivity factor activity enzyme binding histone acetyltransferase binding identical protein binding MutLalpha complex binding nuclear estrogen receptor binding protein-containing complex binding pu... | Mus musculus | Acetylation DNA damage DNA repair DNA replication DNA-binding Isopeptide bond Methylation Nucleus Phosphoprotein Reference proteome Ubl conjugation | MFEARLIQGS | MFEARLIQGSILKKVLEALKDLINEACWDVSSGGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVIKMPSGEFARICRDLSHIGDAVVISCAKNGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVHLTFALRYLNFFTKATPLSPTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEAS | base-excision repair, gap-filling cellular response to hydrogen peroxide cellular response to UV cellular response to xenobiotic stimulus epithelial cell differentiation estrous cycle heart development leading strand elongation liver regeneration mismatch repair mitotic telomere maintenance via semi-conservative replic... |
anatomical structure formation involved in morphogenesis anatomical structure morphogenesis anterior/posterior pattern specification embryonic skeletal system morphogenesis facial nerve structural organization facial nucleus development positive regulation of transcription by RNA polymerase II regulation of transcripti... | nucleoplasm; nucleus | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific protein domain specific binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-spec... | Mus musculus | Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MDYNRMSSFL | MDYNRMSSFLEYPLCNRGPSAYSAPTSFPPCSAPAVDSYAGESRYGGGLPSSALQQNSGYPVQQPPSSLGVSFPSPAPSGYAPAACNPSYGPSQYYSVGQSEGDGSYFHPSSYGAQLGGLPDSYGAGGVGSGPYPPPQPPYGTEQTATFASAYDLLSEDKESPCSSEPSTLTPRTFDWMKVKRNPPKTAKVSELGLGAPGGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGGRMPAGPPGCPKEAAGDASDQSACTSPEASPSSITS | anatomical structure formation involved in morphogenesis anatomical structure morphogenesis anterior/posterior pattern specification embryonic skeletal system morphogenesis facial nerve structural organization facial nucleus development positive regulation of transcription by RNA polymerase II regulation of transcripti... |
cellular response to estradiol stimulus muscle cell fate commitment myoblast differentiation negative regulation of cell population proliferation positive regulation of muscle atrophy positive regulation of myoblast differentiation positive regulation of myotube differentiation positive regulation of skeletal muscle fi... | nucleus; protein-DNA complex; transcription regulator complex | bHLH transcription factor binding DNA-binding transcription activator activity DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific E-box binding identical protein binding protein dimerization activity RNA polymerase II cis-regulatory region sequence-specific D... | Gallus gallus | Activator Developmental protein Differentiation DNA-binding Myogenesis Nucleus Reference proteome Transcription Transcription regulation | MELFETNPYF | MELFETNPYFFPEQRFYDGENFLGSRLQGYEAAAFPERPEVTLCPESRGALEEKDSTLPEHCPGQCLPWACKICKRKTVSIDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQSLLSSLNQQEREQRELRYRPAAPQPAAPSECGSGSSSCSPEWSTQLEFGTNPADHLLSDDQAEDRNLHSLSSIVESIAVEDVAVTFPEERVQN | cellular response to estradiol stimulus muscle cell fate commitment myoblast differentiation negative regulation of cell population proliferation positive regulation of muscle atrophy positive regulation of myoblast differentiation positive regulation of myotube differentiation positive regulation of skeletal muscle fi... |
anterior commissure morphogenesis chondrocyte differentiation club cell differentiation commissural neuron axon guidance DNA replication glial cell differentiation lung ciliated cell differentiation negative regulation of epithelial cell proliferation involved in lung morphogenesis negative regulation of mesenchymal ce... | cerebellar mossy fiber; nucleus | DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding | Gallus gallus | Activator Alternative splicing Direct protein sequencing DNA replication DNA-binding Nucleus Reference proteome Transcription Transcription regulation | MMYSPICLTQ | MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQKWASRLLAKLRKDIRQEFREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSGQPGSPSHNDPAKNPPVYLEDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIGELPSQPYYHDMNSGINLQRSLSSPPSSKRPKTISIDENMEPSPTGDFYPSPNSPAAGSRTWHERDQDMSSPTMKKPEK... | anterior commissure morphogenesis chondrocyte differentiation club cell differentiation commissural neuron axon guidance DNA replication glial cell differentiation lung ciliated cell differentiation negative regulation of epithelial cell proliferation involved in lung morphogenesis negative regulation of mesenchymal ce... |
eosinophil chemotaxis epithelial cell differentiation innate immune response macrophage chemotaxis monocyte chemotaxis mononuclear cell migration mRNA processing negative regulation of endocytosis negative regulation of extrinsic apoptotic signaling pathway negative regulation of immunological synapse formation negativ... | cell surface; collagen-containing extracellular matrix; cytoplasm; cytosol; extracellular exosome; extracellular region; extracellular space; ficolin-1-rich granule membrane; immunological synapse; membrane; mitochondrial inner membrane; nucleoplasm; nucleus; plasma membrane; secretory granule membrane; spliceosomal co... | carbohydrate binding chemoattractant activity IgE binding laminin binding molecular condensate scaffold activity protein phosphatase binding protein phosphatase inhibitor activity RNA binding | Homo sapiens | 3D-structure Acetylation Cytoplasm Differentiation Disulfide bond IgE-binding protein Immunity Innate immunity Lectin mRNA processing mRNA splicing Nucleus Phosphoprotein Reference proteome Repeat Secreted Spliceosome | MADNFSLHDA | MADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI | eosinophil chemotaxis epithelial cell differentiation innate immune response macrophage chemotaxis monocyte chemotaxis mononuclear cell migration mRNA processing negative regulation of endocytosis negative regulation of extrinsic apoptotic signaling pathway negative regulation of immunological synapse formation negativ... |
arachidonic acid secretion lipid catabolic process phospholipid metabolic process | extracellular region | calcium ion binding phospholipase A2 activity toxin activity | Vipera ammodytes ammodytes | 3D-structure Direct protein sequencing Disulfide bond Myotoxin Neurotoxin Presynaptic neurotoxin Secreted Signal Toxin | MRILWIVAVC | MRILWIVAVCLIGVEGSVIEFGKMIQEETDKNPLTSYSFYGCHCGLGNKGKPKDATDRCCFVHSCCYAKLPDCSPKTNRYEYHRENGAIVCGSSTPCKKQICECDRAAAICFRENLKTYNKKYKVYLRFKCKGVSEKC | arachidonic acid secretion lipid catabolic process phospholipid metabolic process extracellular region calcium ion binding phospholipase A2 activity toxin activity Vipera ammodytes ammodytes 3D-structure Direct protein sequencing Disulfide bond Myotoxin Neurotoxin Presynaptic neurotoxin Secreted Signal Toxin MRILWIVAVC... |
apoptotic process MAPK cascade negative regulation of cell population proliferation negative regulation of protein phosphorylation negative regulation of signal transduction negative regulation of smooth muscle cell migration negative regulation of smooth muscle cell proliferation osteoblast differentiation positive re... | endoplasmic reticulum lumen; extracellular region; extracellular space; insulin-like growth factor binding protein complex; insulin-like growth factor ternary complex; nucleus | fibronectin binding insulin-like growth factor binding insulin-like growth factor I binding insulin-like growth factor II binding metal ion binding protein tyrosine phosphatase activator activity | Homo sapiens | 3D-structure Alternative splicing Apoptosis Direct protein sequencing Disulfide bond Glycoprotein Growth factor binding Phosphoprotein Reference proteome Secreted Signal | MQRARPTLWA | MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK | apoptotic process MAPK cascade negative regulation of cell population proliferation negative regulation of protein phosphorylation negative regulation of signal transduction negative regulation of smooth muscle cell migration negative regulation of smooth muscle cell proliferation osteoblast differentiation positive re... |
cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape | cytoplasm | ATP binding magnesium ion binding protein homodimerization activity UDP-N-acetylmuramate-L-alanine ligase activity | Escherichia coli | 3D-structure ATP-binding Cell cycle Cell division Cell shape Cell wall biogenesis/degradation Cytoplasm Direct protein sequencing Ligase Nucleotide-binding Peptidoglycan synthesis Reference proteome | MNTQQLAKLR | MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALES... | cell cycle cell division cell wall organization peptidoglycan biosynthetic process regulation of cell shape cytoplasm ATP binding magnesium ion binding protein homodimerization activity UDP-N-acetylmuramate-L-alanine ligase activity Escherichia coli 3D-structure ATP-binding Cell cycle Cell division Cell shape Cell wall... |
cell surface receptor signaling pathway cellular senescence centriole assembly centrosome cycle mitotic centrosome separation mitotic metaphase chromosome alignment mRNA transport negative regulation of apoptotic process negative regulation of cell population proliferation negative regulation of epidermal growth factor... | annulate lamellae; centrosome; cytoplasm; Flemming body; mitotic spindle; nuclear envelope; nuclear membrane; nuclear pore; nuclear pore central transport channel; protein-containing complex; ribonucleoprotein complex; spindle pole | Hsp70 protein binding Hsp90 protein binding kinesin binding nuclear thyroid hormone receptor binding phospholipid binding protein-containing complex binding PTB domain binding SH2 domain binding signaling receptor complex adaptor activity structural constituent of nuclear pore ubiquitin binding | Rattus norvegicus | 3D-structure Acetylation Coiled coil Cytoplasm Cytoskeleton Direct protein sequencing Disulfide bond Glycoprotein mRNA transport Nuclear pore complex Nucleus Phosphoprotein Protein transport Reference proteome Repeat Translocation Transport | MSGFNFGGTG | MSGFNFGGTGAPAGGFTFGTAKTATTTPATGFSFSASGTGTGGFNFGTPSQPAATTPSTSLFSLATQTSTTQTPGFNFGTTPASGGTGFSLGISTPKLSLSSTAATPATANTGSFGLGSSTLTNAISGASTSSQGTAPTGFVFGSSTTSAPSTGTTGFSFTSGSASQPGASGFNIGSVGSLAQPTALSGSPFTPATLATTTAGATQPAAATPTAATTSAGSTLFASIAAAPASSSTTVLSLSAPATTAATPTAGTLGFSLKAPGAAPGASTTSTTTTTTTTTTTASTSSSTTTTGFALSLKPLVPAGPSSVAATALPASS... | cell surface receptor signaling pathway cellular senescence centriole assembly centrosome cycle mitotic centrosome separation mitotic metaphase chromosome alignment mRNA transport negative regulation of apoptotic process negative regulation of cell population proliferation negative regulation of epidermal growth factor... |
mannose trimming involved in glycoprotein ERAD pathway positive regulation of endoplasmic reticulum unfolded protein response protein alpha-1,2-demannosylation protein folding response to endoplasmic reticulum stress | endoplasmic reticulum; endoplasmic reticulum lumen; mannosyl-oligosaccharide 1,2-alpha-mannosidase complex | protein disulfide isomerase activity protein-disulfide reductase activity unfolded protein binding | Saccharomyces cerevisiae | 3D-structure Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Isomerase Redox-active center Reference proteome Repeat Signal | MKFSAGAVLS | MKFSAGAVLSWSSLLLASSVFAQQEAVAPEDSAVVKLATDSFNEYIQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEKNITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQPAVAVVADLPAYLANETFVTPVIVQSGKIDADFNATFYSMANKHFNDYDFVSAENADDDFKLSIYLPSAMDEPVVYNGKKADIADADVFEKWLQVEALPYFGEIDGSVFAQYVESGLPLGYLFYNDEEELEEYKPLFTELAKKNRGLMNFVSIDARKFGRHAGNLNMKEQFPLFAIHDMT... | mannose trimming involved in glycoprotein ERAD pathway positive regulation of endoplasmic reticulum unfolded protein response protein alpha-1,2-demannosylation protein folding response to endoplasmic reticulum stress endoplasmic reticulum; endoplasmic reticulum lumen; mannosyl-oligosaccharide 1,2-alpha-mannosidase comp... |
action potential chemical synaptic transmission larval locomotory behavior positive regulation of circadian sleep/wake cycle, sleep potassium ion transmembrane transport potassium ion transport protein homooligomerization regulation of heart contraction regulation of synaptic activity | plasma membrane; synapse; voltage-gated potassium channel complex | delayed rectifier potassium channel activity voltage-gated potassium channel activity | Drosophila melanogaster | Alternative splicing Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MVGQLQGGQA | MVGQLQGGQAAGQQQQQQQATQQQQHSKQQQQQQQQQQQQLQLKQHQQQQQDILYQQHNEAIAIARGLQAATPADIGDNQPYYDTSGNVDWERAMGAGGAGAYGGIGIGSLPAAGGAAYHLGPANPAGLVSRHLDYGDGGHLAGPSAGLPAGAVGSGAGAGAGAGASVTGSGSGAGTGTGTGAGSGSGSGAAGKEVRYAPFPVASPTHSIPTTSQQIVGSVGGVGVGGASSQSISGGVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCD... | action potential chemical synaptic transmission larval locomotory behavior positive regulation of circadian sleep/wake cycle, sleep potassium ion transmembrane transport potassium ion transport protein homooligomerization regulation of heart contraction regulation of synaptic activity plasma membrane; synapse; voltage-... |
associative learning chemical synaptic transmission potassium ion transmembrane transport potassium ion transport protein homooligomerization | dendrite; perikaryon; plasma membrane; synapse; voltage-gated potassium channel complex | A-type (transient outward) potassium channel activity voltage-gated potassium channel activity | Drosophila melanogaster | Alternative splicing Cell projection Glycoprotein Ion channel Ion transport Membrane Potassium Potassium channel Potassium transport Reference proteome Transmembrane Transmembrane helix Transport Voltage-gated channel | MASVAAWLPF | MASVAAWLPFARAAAIGWVPIATHPLPPPPMPKDRRKTDDEKLLINVSGRRFETWRNTLEKYPDTLLGSNEREFFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSC... | associative learning chemical synaptic transmission potassium ion transmembrane transport potassium ion transport protein homooligomerization dendrite; perikaryon; plasma membrane; synapse; voltage-gated potassium channel complex A-type (transient outward) potassium channel activity voltage-gated potassium channel acti... |
biofilm matrix disassembly defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium monocyte chemotaxis negative regulation of T cell activation neutrophil activation neutrophil-mediated killing of gram-positive bacterium platelet activation positive regulation ... | cytoplasmic stress granule; cytosol; extracellular space; lysosome; membrane; nucleus; plasma membrane; secretory granule | caspase binding heparin binding peptidase activity receptor ligand activity serine-type endopeptidase activity serine-type peptidase activity | Rattus norvegicus | Antibiotic Antimicrobial Cell membrane Chemotaxis Cytoplasm Direct protein sequencing Disulfide bond Glycoprotein Hydrolase Lysosome Membrane Nucleus Protease Reference proteome Secreted Serine protease Signal Zymogen | MQPLLFLLIF | MQPLLFLLIFVLFQEDEAGKIIGGREARPNSHPYMAFLLIQSPEGLSACGGFLVREDFVLTAGHCFGSSINVTLGAHNIRRQEGTQQHITVLRAIRHPDYNPPPVIQNDIMLLQLRSRARRSRAVKPVALPQATKRVQPGALCTVAGWGLVSQRRGTNVLQEVKLRVQTDQTCANRFQFYNSQTQICVGNPRERKSAFKGDSGGPLVCNNVAQGIVSYGSSSGNPPAVFTRIQSFMPWIKRTMRRLSSRY | biofilm matrix disassembly defense response to fungus defense response to Gram-negative bacterium defense response to Gram-positive bacterium monocyte chemotaxis negative regulation of T cell activation neutrophil activation neutrophil-mediated killing of gram-positive bacterium platelet activation positive regulation ... |
modulation by host of viral transcription positive regulation of proteasomal protein catabolic process positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process | cytosol; extracellular region; ficolin-1-rich granule lumen; membrane; nucleoplasm; nucleus; P-body; proteasome accessory complex; proteasome complex; proteasome regulatory particle, base subcomplex; secretory granule lumen | ATP binding ATP hydrolysis activity identical protein binding proteasome-activating activity | Homo sapiens | 3D-structure Acetylation ATP-binding Cataract Cytoplasm Deafness Direct protein sequencing Host-virus interaction Intellectual disability Neuropathy Nucleotide-binding Nucleus Phosphoprotein Proteasome Reference proteome Ubl conjugation | MNLLPNIESP | MNLLPNIESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGF... | modulation by host of viral transcription positive regulation of proteasomal protein catabolic process positive regulation of transcription by RNA polymerase II proteasome-mediated ubiquitin-dependent protein catabolic process cytosol; extracellular region; ficolin-1-rich granule lumen; membrane; nucleoplasm; nucleus; ... |
NAD catabolic process | external side of plasma membrane | hydrolase activity, acting on glycosyl bonds NAD glycohydrolase activity NAD+ ADP-ribosyltransferase activity NAD+-protein-arginine ADP-ribosyltransferase activity nucleotidyltransferase activity | Mus musculus | Cell membrane Disulfide bond Glycoprotein Glycosyltransferase GPI-anchor Hydrolase Lipoprotein Membrane NAD NADP Nucleotidyltransferase Reference proteome Signal Transferase | MPSNNFKFFL | MPSNNFKFFLTWWLTQQVTGLAVPFMLDMAPNAFDDQYEGCVEDMEKKAPQLLQEDFNMNEELKLEWEKAEIKWKEIKNCMSYPAGFHDFHGTALVAYTGNIHRSLNEATREFKINPGNFHYKAFHYYLTRALQLLSDQGCRSVYRGTNVRFRYTGKGSVRFGHFASSSLNRSVATSSPFFNGQGTLFIIKTCLGAHIKHCSYYTHEEEVLIPGYEVFHKVKTQSVERYIQISLDSPKRKKSNFNCFYSGSTQAANVSSLGSRESCVSLFLVVLLGLLVQQLTLAEP | NAD catabolic process external side of plasma membrane hydrolase activity, acting on glycosyl bonds NAD glycohydrolase activity NAD+ ADP-ribosyltransferase activity NAD+-protein-arginine ADP-ribosyltransferase activity nucleotidyltransferase activity Mus musculus Cell membrane Disulfide bond Glycoprotein Glycosyltransf... |
NAD catabolic process | external side of plasma membrane | hydrolase activity, acting on glycosyl bonds NAD glycohydrolase activity NAD+ ADP-ribosyltransferase activity NAD+-protein-arginine ADP-ribosyltransferase activity nucleotidyltransferase activity | Rattus norvegicus | Cell membrane Disulfide bond Glycoprotein Glycosyltransferase GPI-anchor Hydrolase Lipoprotein Membrane NAD NADP Nucleotidyltransferase Reference proteome Signal Transferase | MPSNICKFFL | MPSNICKFFLTWWLIQQVTGLTGPLMLDTAPNAFDDQYEGCVNKMEEKAPLLLKEDFNKSEKLKVAWEEAKKRWNNIKPSMSYPKGFNDFHGTALVAYTGSIGVDFNRAVREFKENPGQFHYKAFHYYLTRALQLLSNGDCHSVYRGTKTRFHYTGAGSVRFGQFTSSSLSKTVAQSPEFFSDDGTLFIIKTCLGVYIKEFSFYPDQEEVLIPGYEVYQKVRTQGYNEIFLDSPKRKKSNYNCLYSSAGTRESCVSLFLVVLTSLLVQLLCLAEP | NAD catabolic process external side of plasma membrane hydrolase activity, acting on glycosyl bonds NAD glycohydrolase activity NAD+ ADP-ribosyltransferase activity NAD+-protein-arginine ADP-ribosyltransferase activity nucleotidyltransferase activity Rattus norvegicus Cell membrane Disulfide bond Glycoprotein Glycosylt... |
binding of sperm to zona pellucida chaperone-mediated protein folding positive regulation of establishment of protein localization to telomere positive regulation of protein localization to Cajal body positive regulation of telomerase activity positive regulation of telomerase RNA localization to Cajal body positive re... | acrosomal vesicle; cell body; centrosome; chaperonin-containing T-complex; cytosol; extracellular exosome; Golgi apparatus; heterochromatin; microtubule; pericentriolar material; zona pellucida receptor complex | ATP binding ATP hydrolysis activity ATP-dependent protein folding chaperone protein folding chaperone RNA binding ubiquitin protein ligase binding unfolded protein binding | Homo sapiens | 3D-structure Acetylation ATP-binding Chaperone Cytoplasm Cytoskeleton Direct protein sequencing Nucleotide-binding Phosphoprotein Reference proteome | MEGPLSVFGD | MEGPLSVFGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIA... | binding of sperm to zona pellucida chaperone-mediated protein folding positive regulation of establishment of protein localization to telomere positive regulation of protein localization to Cajal body positive regulation of telomerase activity positive regulation of telomerase RNA localization to Cajal body positive re... |
3'-phosphoadenosine 5'-phosphosulfate metabolic process 4-nitrophenol metabolic process catecholamine metabolic process estrogen metabolic process ethanol catabolic process flavonoid metabolic process regulation of blood pressure response to activity response to glucocorticoid response to insecticide sulfation thyroid ... | cytoplasm | 3'-phosphoadenosine 5'-phosphosulfate binding aryl sulfotransferase activity flavonol 3-sulfotransferase activity identical protein binding steroid sulfotransferase activity sulfotransferase activity | Rattus norvegicus | Cytoplasm Direct protein sequencing Lipid metabolism Phosphoprotein Reference proteome Steroid metabolism Transferase | MEFSRPPLVH | MEFSRPPLVHVKGIPLIKYFAETIGPLQNFTAWPDDLLISTYPKSGTTWMSEILDMIYQGGKLEKCGRAPIYARVPFLEFKCPGVPSGLETLEETPAPRLLKTHLPLSLLPQSLLDQKVKVIYIARNAKDVVVSYYNFYNMAKLHPDPGTWDSFLENFMDGEVSYGSWYQHVKEWWELRHTHPVLYLFYEDIKENPKREIKKILEFLGRSLPEETVDSIVHHTSFKKMKENCMTNYTTIPTEIMDHNVSPFMRKGTTGDWKNTFTVAQNERFDAHYAKTMTDCDFKFRCEL | 3'-phosphoadenosine 5'-phosphosulfate metabolic process 4-nitrophenol metabolic process catecholamine metabolic process estrogen metabolic process ethanol catabolic process flavonoid metabolic process regulation of blood pressure response to activity response to glucocorticoid response to insecticide sulfation thyroid ... |
negative regulation by symbiont of host translation protein autoubiquitination protein polyubiquitination suppression by symbiont of host cell-mediated immune response suppression of host innate immune response ubiquitin-dependent protein catabolic process | extracellular region; host cell cytoplasm | ubiquitin-protein transferase activity | Shigella flexneri | Direct protein sequencing Host cytoplasm Leucine-rich repeat Plasmid Reference proteome Repeat Secreted Transferase Ubl conjugation Ubl conjugation pathway Virulence | MKPINNHSFF | MKPINNHSFFRSLCGLSCISRLSVEEQCTRDYHRIWDDWAREGTTTENRIQAVRLLKICLDTREPVLNLSLLKLRSLPPLPLHIRELNISNNELISLPENSPLLTELHVNGNNLNILPTLPSQLIKLNISFNRNLSCLPSLPPYLQSLSARFNSLETLPELPSTLTILRIEGNRLTVLPELPHRLQELFVSGNRLQELPEFPQSLKYLKVGENQLRRLSRLPQELLALDVSNNLLTSLPENIITLPICTNVNISGNPLSTHVLQSLQRLTSSPDYHGPQIYFSMSDGQQNTLHRPLADAVTAWFPENKQSDVSQIWHAFE... | negative regulation by symbiont of host translation protein autoubiquitination protein polyubiquitination suppression by symbiont of host cell-mediated immune response suppression of host innate immune response ubiquitin-dependent protein catabolic process extracellular region; host cell cytoplasm ubiquitin-protein tra... |
effector-mediated activation of programmed cell death in host protein ubiquitination symbiont-mediated suppression of host programmed cell death ubiquitin-dependent protein catabolic process | extracellular region; host cell cytoplasm | ubiquitin protein ligase activity | Shigella flexneri | 3D-structure Direct protein sequencing Host cytoplasm Leucine-rich repeat Plasmid Reference proteome Repeat Secreted Transferase Ubl conjugation Ubl conjugation pathway Virulence | MFSVNNTHSS | MFSVNNTHSSVSCSPSINSNSTSNEHYLRILTEWEKNSSPGEERGIAFNRLSQCFQNQEAVLNLSDLNLTSLPELPKHISALIVENNKLTSLPKLPAFLKELNADNNRLSVIPELPESLTTLSVRSNQLENLPVLPNHLTSLFVENNRLYNLPALPEKLKFLHVYYNRLTTLPDLPDKLEILCAQRNNLVTFPQFSDRNNIRQKEYYFHFNQITTLPESFSQLDSSYRINISGNPLSTRVLQSLQRLTSSPDYHGPQIYFSMSDGQQNTLHRPLADAVTAWFPENKQSDVSQIWHAFEHEEHANTFSAFLDRLSDTVSAR... | effector-mediated activation of programmed cell death in host protein ubiquitination symbiont-mediated suppression of host programmed cell death ubiquitin-dependent protein catabolic process extracellular region; host cell cytoplasm ubiquitin protein ligase activity Shigella flexneri3D-structure Direct protein sequenci... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 2 subtype A | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of h... | MCGKSLLCVA | MCGKSLLCVASLLASAYLVYCTQYVTVFYGVPVWRNASIPLFCATKNRDTWGTIQCKPDNDDYQEITLNVTEAFDAWDNTVTEQAVEDVWSLFETSIKPCVKLTPLCVAMSCNSTTNNTTTTGSTTGMSEINETSPSYSDNCTGLGKEEIVNCQFYMTGLERDKKKQYNETWYSKDVVCESNNTKDGKNRCYMNHCNTSVITESCDKHYWDAIKFRYCAPPGYALLRCNDTNYSGFEPKCSKVVASTCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLSIHCKRPGNKTVVPITLMSGLVFHSQPI... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membra... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 2 subtype A | 3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral rel... | MGARNSVLRG | MGARNSVLRGKKADELEKIRLRPSGKKKYRLKHIVWAANELDKFGLAESLLESKEGCQKILTVLDPLVPTGSENLKSLFNTVCVIWCLHAEEKVKDTEEAKKLVQRHLGAETGTAEKMPSTSRPTAPPSGRGRNFPVQQTGGGNYIHVPLSPRTLNAWVKLVEDKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINDEAADWDAQHPIPGPLPAGQLRDPRGSDIAGTTSTVEEQIQWMYRPQNPVPVGNIYRRWIQIGLQKCVRMYNPTNILDVKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWM... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 2 subtype A 3D-structure AIDS Capsid protein Host cell membrane Host cyt... |
dephosphorylation insulin receptor signaling pathway integrin-mediated signaling pathway modulation of chemical synaptic transmission positive regulation of oligodendrocyte differentiation regulation of focal adhesion assembly | focal adhesion; membrane; receptor complex; Schaffer collateral - CA1 synapse; synaptic membrane | protein tyrosine phosphatase activity protein-containing complex binding | Mus musculus | 3D-structure Alternative splicing Cell junction Cell membrane Direct protein sequencing Glycoprotein Hydrolase Membrane Phosphoprotein Protein phosphatase Reference proteome Repeat Signal Transmembrane Transmembrane helix | MDSWFILVLF | MDSWFILVLFGSGLIHVSANNATTVSPSLGTTRLIKTSTTELAKEENKTSNSTSSVISLSVAPTFSPNLTLEPTYVTTVNSSHSDNGTRRAASTESGGTTISPNGSWLIENQFTDAITEPWEGNSSTAATTPETFPPADETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPFLSLAVSKDAVKALNKTTPLLERRFIGKSNSRGCLSDDHSRVHLTPVEGVPDS... | dephosphorylation insulin receptor signaling pathway integrin-mediated signaling pathway modulation of chemical synaptic transmission positive regulation of oligodendrocyte differentiation regulation of focal adhesion assembly focal adhesion; membrane; receptor complex; Schaffer collateral - CA1 synapse; synaptic membr... |
arachidonic acid metabolic process establishment of skin barrier fatty acid oxidation hepoxilin biosynthetic process leukotriene A4 metabolic process linoleic acid metabolic process lipid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxin B4 biosynthetic process lipoxygenase pathway negative regu... | cytoplasm; cytosol; extracellular exosome; membrane; sarcolemma | arachidonate 12(S)-lipoxygenase activity arachidonate 15-lipoxygenase activity hepoxilin-epoxide hydrolase activity iron ion binding linoleate 13S-lipoxygenase activity | Homo sapiens | 3D-structure Cytoplasm Dioxygenase Fatty acid metabolism Hydrolase Iron Lipid metabolism Membrane Metal-binding Oxidoreductase Phosphoprotein Reference proteome | MGRYRIRVAT | MGRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAEDLGLLQFVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARLPGDNALDMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFEWTLKAGALEMALKRVYTLLSSWNCLEDFDQIFWGQKSALAEKVRQCWQDDELFSYQFLNGANPMLLRRSTSLPSRLVLPSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPLVMLKMEPNGKLQPMVIQIQP... | arachidonic acid metabolic process establishment of skin barrier fatty acid oxidation hepoxilin biosynthetic process leukotriene A4 metabolic process linoleic acid metabolic process lipid metabolic process lipid oxidation lipoxin A4 biosynthetic process lipoxin B4 biosynthetic process lipoxygenase pathway negative regu... |
abscisic acid-activated signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway blue light signaling pathway cell death G protein-coupled receptor signaling pathway gibberellic acid mediated signaling pathway L-phenylalanine biosynthetic process positive regulation of abscisic acid-a... | endoplasmic reticulum membrane; heterotrimeric G-protein complex; peroxisome; plasma membrane; plasmodesma | channel regulator activity G protein-coupled receptor binding G-protein beta/gamma-subunit complex binding GTP binding GTPase activity GTPase binding GTPase inhibitor activity metal ion binding | Arabidopsis thaliana | 3D-structure Abscisic acid signaling pathway Cell membrane GTP-binding Lipoprotein Magnesium Membrane Metal-binding Myristate Nucleotide-binding Palmitate Reference proteome Transducer | MGLLCSRSRH | MGLLCSRSRHHTEDTDENTQAAEIERRIEQEAKAEKHIRKLLLLGAGESGKSTIFKQIKLLFQTGFDEGELKSYVPVIHANVYQTIKLLHDGTKEFAQNETDSAKYMLSSESIAIGEKLSEIGGRLDYPRLTKDIAEGIETLWKDPAIQETCARGNELQVPDCTKYLMENLKRLSDINYIPTKEDVLYARVRTTGVVEIQFSPVGENKKSGEVYRLFDVGGQRNERRKWIHLFEGVTAVIFCAAISEYDQTLFEDEQKNRMMETKELFDWVLKQPCFEKTSFMLFLNKFDIFEKKVLDVPLNVCEWFRDYQPVSSGKQEI... | abscisic acid-activated signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway blue light signaling pathway cell death G protein-coupled receptor signaling pathway gibberellic acid mediated signaling pathway L-phenylalanine biosynthetic process positive regulation of abscisic acid-a... |
cellular response to hormone stimulus female pregnancy negative regulation of canonical Wnt signaling pathway positive regulation of activated T cell proliferation regulation of insulin-like growth factor receptor signaling pathway response to estradiol response to estrogen response to glucocorticoid response to mechan... | apical plasma membrane; extracellular exosome; extracellular region; extracellular space | insulin-like growth factor I binding insulin-like growth factor II binding signaling receptor binding | Homo sapiens | 3D-structure Direct protein sequencing Disulfide bond Glycoprotein Growth factor binding Growth regulation Reference proteome Secreted Signal | MLPRVGCPAL | MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAPPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELPLQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKPLKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERISTMRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEARGVH... | cellular response to hormone stimulus female pregnancy negative regulation of canonical Wnt signaling pathway positive regulation of activated T cell proliferation regulation of insulin-like growth factor receptor signaling pathway response to estradiol response to estrogen response to glucocorticoid response to mechan... |
amyloid-beta clearance by transcytosis canonical Wnt signaling pathway early endosome to late endosome transport endocytosis intracellular protein transport modulation by host of viral process phagocytosis positive regulation of exocytosis receptor internalization regulation of endosome size regulation of filopodium as... | actin cytoskeleton; axon; cytoplasmic side of early endosome membrane; cytosol; dendrite; early endosome; early phagosome; endomembrane system; exocytic vesicle; lipid droplet; melanosome; membrane raft; nucleoplasm; phagocytic vesicle; phagocytic vesicle membrane; plasma membrane; postsynaptic early endosome; ruffle; ... | G protein activity GDP binding GTP binding GTPase activity | Canis lupus familiaris | Cell membrane Cell projection Cytoplasm Cytoplasmic vesicle Endocytosis Endosome GTP-binding Hydrolase Lipoprotein Membrane Nucleotide-binding Phagocytosis Phosphoprotein Prenylation Protein transport Reference proteome Transport | MANRGATRPN | MANRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVDLTEPTQPTRSQCCSN | amyloid-beta clearance by transcytosis canonical Wnt signaling pathway early endosome to late endosome transport endocytosis intracellular protein transport modulation by host of viral process phagocytosis positive regulation of exocytosis receptor internalization regulation of endosome size regulation of filopodium as... |
early endosome to late endosome transport endosome to lysosome transport endosome to plasma membrane protein transport epidermal growth factor catabolic process lipid catabolic process lipophagy phagosome acidification phagosome-lysosome fusion | autophagosome membrane; cytosol; exocytic vesicle; late endosome; late endosome membrane; lipid droplet; lysosomal membrane; lysosome; melanosome membrane; mitochondrial membrane; mitochondrion; phagocytic vesicle; phagocytic vesicle membrane; synaptic vesicle membrane | G protein activity GTP binding | Canis lupus familiaris | Acetylation Autophagy Cytoplasmic vesicle Endosome GTP-binding Hydrolase Isopeptide bond Lipid degradation Lipid droplet Lipid metabolism Lipoprotein Lysosome Membrane Methylation Mitochondrion Nucleotide-binding Phosphoprotein Prenylation Protein transport Reference proteome Transport Ubl conjugation | MTSRKKVLLK | MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKTSAESCSC | early endosome to late endosome transport endosome to lysosome transport endosome to plasma membrane protein transport epidermal growth factor catabolic process lipid catabolic process lipophagy phagosome acidification phagosome-lysosome fusion autophagosome membrane; cytosol; exocytic vesicle; late endosome; late endo... |
apoptotic process bone mineralization central nervous system myelin formation chromosome segregation determination of adult lifespan embryonic cleavage embryonic organ development erythrocyte maturation extracellular matrix organization hair cell differentiation hair follicle maturation hematopoietic stem cell differen... | CAK-ERCC2 complex; cytoplasm; cytosol; MMXD complex; nucleoplasm; nucleus; spindle; transcription factor TFIID complex; transcription factor TFIIH core complex; transcription factor TFIIH holo complex | 4 iron, 4 sulfur cluster binding 5'-3' DNA helicase activity ATP binding ATP hydrolysis activity damaged DNA binding DNA helicase activity metal ion binding protein-macromolecule adaptor activity | Homo sapiens | 3D-structure 4Fe-4S Alternative splicing ATP-binding Cataract Chromosome partition Cockayne syndrome Cytoplasm Cytoskeleton Deafness Disease variant DNA damage DNA repair DNA-binding Dwarfism Helicase Host-virus interaction Hydrolase Ichthyosis Iron Iron-sulfur Magnesium Metal-binding Nucleotide-binding Nucleus Referen... | MKLNVDGLLV | MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVP... | apoptotic process bone mineralization central nervous system myelin formation chromosome segregation determination of adult lifespan embryonic cleavage embryonic organ development erythrocyte maturation extracellular matrix organization hair cell differentiation hair follicle maturation hematopoietic stem cell differen... |
cytoplasmic translation ribosomal large subunit biogenesis rRNA processing translation | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; extracellular exosome; membrane; synapse | RNA binding structural constituent of ribosome tRNA binding | Homo sapiens | 3D-structure Acetylation Cytoplasm Diamond-Blackfan anemia Disease variant Reference proteome Ribonucleoprotein Ribosomal protein RNA-binding tRNA-binding | MSGRLWSKAI | MSGRLWSKAIFAGYKRGLRNQREHTALLKIEGVYARDETEFYLGKRCAYVYKAKNNTVTPGGKPNKTRVIWGKVTRAHGNSGMVRAKFRSNLPAKAIGHRIRVMLYPSRI | cytoplasmic translation ribosomal large subunit biogenesis rRNA processing translation cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; extracellular exosome; membrane; synapse RNA binding structural constituent of ribosome tRNA binding Homo sapiens 3D-structure Acetylation Cytoplasm Diamond-B... |
cell migration cell-matrix adhesion endodermal cell differentiation epithelial cell-cell adhesion integrin-mediated signaling pathway stress fiber assembly transforming growth factor beta receptor signaling pathway wound healing, spreading of epidermal cells | cell surface; extracellular exosome; focal adhesion; integrin alphav-beta5 complex; integrin complex; phagocytic vesicle; plasma membrane; receptor complex | integrin binding metal ion binding virus receptor activity | Homo sapiens | 3D-structure Calcium Cell adhesion Cell membrane Disulfide bond EGF-like domain Glycoprotein Host cell receptor for virus entry Host-virus interaction Integrin Magnesium Membrane Metal-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane Transmembrane helix | MPRAPAPLYA | MPRAPAPLYACLLGLCALLPRLAGLNICTSGSATSCEECLLIHPKCAWCSKEDFGSPRSITSRCDLRANLVKNGCGGEIESPASSFHVLRSLPLSSKGSGSAGWDVIQMTPQEIAVNLRPGDKTTFQLQVRQVEDYPVDLYYLMDLSLSMKDDLDNIRSLGTKLAEEMRKLTSNFRLGFGSFVDKDISPFSYTAPRYQTNPCIGYKLFPNCVPSFGFRHLLPLTDRVDSFNEEVRKQRVSRNRDAPEGGFDAVLQAAVCKEKIGWRKDALHLLVFTTDDVPHIALDGKLGGLVQPHDGQCHLNEANEYTASNQMDYPSLA... | cell migration cell-matrix adhesion endodermal cell differentiation epithelial cell-cell adhesion integrin-mediated signaling pathway stress fiber assembly transforming growth factor beta receptor signaling pathway wound healing, spreading of epidermal cells cell surface; extracellular exosome; focal adhesion; integrin... |
apical protein localization cell migration cilium assembly dendritic spine development endoplasmic reticulum to Golgi vesicle-mediated transport establishment or maintenance of epithelial cell apical/basal polarity intracellular protein transport learning negative regulation of apoptotic process positive regulation of ... | cytosol; dendritic spine; extracellular exosome; glutamatergic synapse; Golgi membrane; membrane; plasma membrane; ruffle membrane | epidermal growth factor receptor binding GTP binding GTPase activity guanyl-nucleotide exchange factor activity NAD+-protein-arginine ADP-ribosyltransferase activity phospholipase D activator activity | Homo sapiens | 3D-structure ER-Golgi transport Golgi apparatus GTP-binding Lipoprotein Membrane Myristate Nucleotide-binding Phosphoprotein Protein transport Reference proteome Transport | MGLTISSLFS | MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAVLLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR | apical protein localization cell migration cilium assembly dendritic spine development endoplasmic reticulum to Golgi vesicle-mediated transport establishment or maintenance of epithelial cell apical/basal polarity intracellular protein transport learning negative regulation of apoptotic process positive regulation of ... |
gamma-aminobutyric acid biosynthetic process glutamate catabolic process locomotory exploration behavior response to ethanol response to morphine response to xenobiotic stimulus social behavior | axon; axon terminus; cell cortex; cytoplasm; GABA-ergic synapse; inhibitory synapse; neuron projection terminus; presynapse; presynaptic active zone; synapse | glutamate binding glutamate decarboxylase activity identical protein binding protein-containing complex binding pyridoxal phosphate binding | Rattus norvegicus | Decarboxylase Lyase Neurotransmitter biosynthesis Phosphoprotein Pyridoxal phosphate Reference proteome | MASSTPSPAT | MASSTPSPATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFRERQASKNLLSCENSDPGARFRRTETDFSNLFAQDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIIGWSNKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIP... | gamma-aminobutyric acid biosynthetic process glutamate catabolic process locomotory exploration behavior response to ethanol response to morphine response to xenobiotic stimulus social behavior axon; axon terminus; cell cortex; cytoplasm; GABA-ergic synapse; inhibitory synapse; neuron projection terminus; presynapse; p... |
activation of protein kinase B activity adenylate cyclase-activating adrenergic receptor signaling pathway adrenergic receptor signaling pathway angiogenesis cell-cell signaling female pregnancy G protein-coupled receptor signaling pathway MAPK cascade negative regulation of epinephrine secretion negative regulation of... | cell surface; cytosol; intracellular membrane-bounded organelle; plasma membrane | alpha2-adrenergic receptor activity epinephrine binding | Homo sapiens | 3D-structure Cell membrane Disulfide bond Epilepsy G-protein coupled receptor Lipoprotein Membrane Palmitate Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MDHQDPYSVQ | MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPA... | activation of protein kinase B activity adenylate cyclase-activating adrenergic receptor signaling pathway adrenergic receptor signaling pathway angiogenesis cell-cell signaling female pregnancy G protein-coupled receptor signaling pathway MAPK cascade negative regulation of epinephrine secretion negative regulation of... |
actin cytoskeleton organization actin filament bundle assembly muscle cell development sarcomere organization | cell junction; cell projection; cortical actin cytoskeleton; focal adhesion; plasma membrane; Z disc | actin binding actin filament binding calcium ion binding | Drosophila melanogaster | Actin-binding Alternative splicing Calcium Cytoplasm Metal-binding Reference proteome Repeat | MMMENGLSME | MMMENGLSMEYGDGYMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVGNNTALPDERAVMTYVSSYYHCFSGAQKAETAANRICKVLKVNQENERLMEEYERLASDLLE... | actin cytoskeleton organization actin filament bundle assembly muscle cell development sarcomere organization cell junction; cell projection; cortical actin cytoskeleton; focal adhesion; plasma membrane; Z disc actin binding actin filament binding calcium ion binding Drosophila melanogaster Actin-binding Alternative sp... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 2 subtype A | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Inhibition of h... | MEPGRNQLFV | MEPGRNQLFVVILLTSACLVYCSQYVTVFYGIPAWKNASIPLFCATKNRDTWGTIQCLPDNDDYQEIILNVTEAFDAWNNTVTEQAVEDVWHLFETSIKPCVKLTPLCVAMNCSRVQGNTTTPNPRTSSSTTSRPPTSAASIINETSNCIENNTCAGLGYEEMMQCEFNMKGLEQDKKRRYKDTWYLEDVVCDNTTAGTCYMRHCNTSIIKESCDKHYWDAMRFRYCAPPGFALLRCNDTNYSGFEPKCTKVVAASCTRMMETQTSTWFGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLTMRCKRPGNKTVLPITLMS... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane suppression by virus of host tetherin activity suppression by virus of host type I interferon-mediated signaling pathway virion attachment to host cell host cell endosome membrane; host cell plasma membrane; membra... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 2 subtype A | 3D-structure AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Phosphoprotein Reference proteome Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucl... | MGARNSVLRG | MGARNSVLRGKKADELEKVRLRPGGKKKYRLKHIVWAANELDKFGLAESLLESKEGCQKILRVLDPLVPTGSENLKSLFNTVCVIWCLHAEEKVKDTEEAKKLAQRHLVAETGTAEKMPNTSRPTAPPSGKRGNYPVQQAGGNYVHVPLSPRTLNAWVKLVEEKKFGAEVVPGFQALSEGCTPYDINQMLNCVGDHQAAMQIIREIINEEAADWDSQHPIPGPLPAGQLRDPRGSDIAGTTSTVDEQIQWMYRPQNPVPVGNIYRRWIQIGLQKCVRKYNPTNILDIKQGPKEPFQSYVDRFYKSLRAEQTDPAVKNWMT... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 2 subtype A 3D-structure AIDS Capsid protein Host cell membrane Host cyt... |
cytoplasmic translation modification-dependent protein catabolic process protein modification process protein ubiquitination translation ubiquitin-dependent protein catabolic process | cytosol; cytosolic large ribosomal subunit; cytosolic small ribosomal subunit; nucleus | protein tag activity structural constituent of ribosome ubiquitin protein ligase binding | Drosophila melanogaster | 3D-structure Cytoplasm Isopeptide bond Nucleus Reference proteome Ribonucleoprotein Ribosomal protein Ubl conjugation | MQIFVKTLTG | MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLRILAQKYNCDKMICRKCYARLHPRATNCRKKKCGHTNNLRPKKKLK | cytoplasmic translation modification-dependent protein catabolic process protein modification process protein ubiquitination translation ubiquitin-dependent protein catabolic process cytosol; cytosolic large ribosomal subunit; cytosolic small ribosomal subunit; nucleus protein tag activity structural constituent of rib... |
anatomical structure development Bolwig's organ morphogenesis cell differentiation cell fate commitment cell fate specification insect visual primordium development inter-male aggressive behavior mushroom body development negative regulation of transcription by RNA polymerase II neuroblast development neuroblast divisi... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific nuclear receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription corepressor binding zinc ion binding | Drosophila melanogaster | Activator Developmental protein DNA-binding Metal-binding Nucleus Receptor Reference proteome Repressor Transcription Transcription regulation Zinc Zinc-finger | MQSSEGSPDM | MQSSEGSPDMMDQKYNSVRLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKRSIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRHMAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPSAAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHLFKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMNFAQLLFVYESENANREIMGMVTREVHAFQEVLNQL... | anatomical structure development Bolwig's organ morphogenesis cell differentiation cell fate commitment cell fate specification insect visual primordium development inter-male aggressive behavior mushroom body development negative regulation of transcription by RNA polymerase II neuroblast development neuroblast divisi... |
angiogenesis blood vessel diameter maintenance blood vessel remodeling c-di-GMP signaling cellular response to glycoprotein cGMP biosynthetic process chromosome organization cumulus cell differentiation gastric emptying growth plate cartilage chondrocyte differentiation growth plate cartilage chondrocyte proliferation ... | extracellular region; protein-containing complex | hormone activity hormone receptor binding signaling receptor binding | Sus scrofa | Cleavage on pair of basic residues Direct protein sequencing Disulfide bond Hormone Osteogenesis Reference proteome Secreted Signal Vasoactive | MHLSQLLACA | MHLSQLLACALLLTLLSLRPSEAKPGAPPKVPRTPPGEEVAEPQAAGGGQKKGDKTPGGGGANLKGDRSRLLRDLRVDTKSRAAWARLLHEHPNARKYKGGNKKGLSKGCFGLKLDRIGSMSGLGC | angiogenesis blood vessel diameter maintenance blood vessel remodeling c-di-GMP signaling cellular response to glycoprotein cGMP biosynthetic process chromosome organization cumulus cell differentiation gastric emptying growth plate cartilage chondrocyte differentiation growth plate cartilage chondrocyte proliferation ... |
distributive segregation establishment of meiotic spindle orientation female meiotic nuclear division meiotic chromosome segregation microtubule-based movement positive regulation of microtubule polymerization spindle assembly involved in female meiosis I | cytoplasm; kinesin complex; microtubule | ATP binding ATP hydrolysis activity microtubule binding microtubule motor activity microtubule plus-end binding | Drosophila melanogaster | 3D-structure ATP-binding Coiled coil Cytoplasm Cytoskeleton Microtubule Motor protein Nucleotide-binding Reference proteome | MEGAKLSAVR | MEGAKLSAVRIAVREAPYRQFLGRREPSVVQFPPWSDGKSLIVDQNEFHFDHAFPATISQDEMYQALILPLVDKLLEGFQCTALAYGQTGTGKSYSMGMTPPGEILPEHLGILPRALGDIFERVTARQENNKDAIQVYASFIEIYNEKPFDLLGSTPHMPMVAARCQRCTCLPLHSQADLHHILELGTRNRRVRPTNMNSNSSRSHAIVTIHVKSKTHHSRMNIVDLAGSEGVRRTGHEGVARQEGVNINLGLLSINKVVMSMAAGHTVIPYRDSVLTTVLQASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKL... | distributive segregation establishment of meiotic spindle orientation female meiotic nuclear division meiotic chromosome segregation microtubule-based movement positive regulation of microtubule polymerization spindle assembly involved in female meiosis I cytoplasm; kinesin complex; microtubule ATP binding ATP hydrolys... |
animal organ morphogenesis anterior/posterior axis specification anterior/posterior pattern specification bone morphogenesis cell differentiation pattern specification process positive regulation of transcription by RNA polymerase II regulation of somitogenesis regulation of transcription by RNA polymerase II | nucleus | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity methyl-CpG binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding sequence-specific double-stranded DN... | Mus musculus | Activator Developmental protein DNA-binding Homeobox Nucleus Reference proteome Transcription Transcription regulation | MYVGYVLDKD | MYVGYVLDKDSPVYPGPARPSSLGLGPPTYAPPGPAPAPPQYPDFAGYTHVEPAPAPPPTWAAPFPAPKDDWAAAYGPGPTASAASPAPLAFGPPPDFSPVPAPPGPGPGILAQSLGAPGAPSSPGAPRRTPYEWMRRSVAAAGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPLPPTQLPLPLDGTPTPSGPPLGSLCPTNAGLLGTPSPVPVKEEFLP | animal organ morphogenesis anterior/posterior axis specification anterior/posterior pattern specification bone morphogenesis cell differentiation pattern specification process positive regulation of transcription by RNA polymerase II regulation of somitogenesis regulation of transcription by RNA polymerase II nucleus D... |
positive regulation of DNA-templated transcription | nucleus | nuclear receptor activity nuclear retinoid X receptor binding protein heterodimerization activity protein homodimerization activity sequence-specific DNA binding thyroid hormone binding zinc ion binding | Xenopus laevis | DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MDQNLSGLDC | MDQNLSGLDCLSEPDEKRWPDGKRKRKNSQCMGKSGMSGDSLVSLPPAGYIPSYLDKDEPCVVCSDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYDGCCIIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEENRVRRRKEEMIKTLQQRPEPSSEEWELIRIVTEAHRSTNAQGSHWKQRRKFLPEDIGQSPMASMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELTCEDQIILLKGCCMEIMSLRAAVRYDPDSETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGRSLAAFNLD... | positive regulation of DNA-templated transcription nucleus nuclear receptor activity nuclear retinoid X receptor binding protein heterodimerization activity protein homodimerization activity sequence-specific DNA binding thyroid hormone binding zinc ion binding Xenopus laevis DNA-binding Metal-binding Nucleus Receptor ... |
negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II | nucleus | nuclear receptor activity protein heterodimerization activity sequence-specific DNA binding thyroid hormone binding zinc ion binding | Xenopus laevis | Alternative splicing DNA-binding Metal-binding Nucleus Receptor Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MPSSMSGYIP | MPSSMSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDNKRLAKRKLIEENREKRRKDEIQKSLVQKPEPTQEEWELIQVVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFSLDDTEVALLQAVLLMSSDRPGLASVERIEKCQEGFLLAFEHYIN... | negative regulation of DNA-templated transcription negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II nucleus nuclear receptor activity protein heterodimerization activity sequence-specific DNA binding th... |
circadian rhythm cold acclimation hydrogen peroxide catabolic process regulation of cellular response to heat response to abscisic acid response to absence of light response to auxin response to cadmium ion response to heat response to hydrogen peroxide response to oxidative stress response to reactive oxygen species r... | cytoplasm; peroxisome; plasma membrane | catalase activity heme binding metal ion binding | Zea mays | Heme Hydrogen peroxide Iron Metal-binding Oxidoreductase Peroxidase Peroxisome Reference proteome | MDPYKHRPSS | MDPYKHRPSSGSNSSFWTTNSGAPVWNNNSALTVGQRGPILLEDYHLIEKLAQFDRERIPERVVHARGASAKGFFEVTHDVSHLTCADFLRAPGVQTPVIVRFSTVVHERGSPETLRDPRGFAVKFYTREGNFDLVGNNMPVFFIRDGMKFPDMVHAFKPNPKTNLQENWRIVDFFSHHPESLHMFTFLFDDVGIPLNYRHMEGFGVNTYSLINRDGKPHLVKFHWKPTCGVKCLLDNEAVTVGGTCHSHATKDLYDSIAAGNYPEWKLYIQTIDLDHEDKFDFDPLDVTKTWPEDIIPLQPVGRMVLNKNVDNFFAENE... | circadian rhythm cold acclimation hydrogen peroxide catabolic process regulation of cellular response to heat response to abscisic acid response to absence of light response to auxin response to cadmium ion response to heat response to hydrogen peroxide response to oxidative stress response to reactive oxygen species r... |
circadian rhythm cold acclimation hydrogen peroxide catabolic process response to auxin response to hydrogen peroxide response to oxidative stress response to reactive oxygen species response to xenobiotic stimulus | cytoplasm; mitochondrion; peroxisome; plasma membrane | catalase activity heme binding metal ion binding | Zea mays | Heme Hydrogen peroxide Iron Metal-binding Mitochondrion Oxidoreductase Peroxidase Reference proteome | MTMDPTKFRP | MTMDPTKFRPSSSHDTTVTTTNAGAPVWNDNEALTVGPRGPILLEDYHLIEKVAHFARERIPERVVHARGASAKGFFECTHDVTSLTCADFLRAPGVRTPVIVRFSTVIHERGSPETIRDPRGFAVKFYTREGNWDLLGNNFPVFFIRDGIKFPDVIHAFKPNPRSHVQEYWRVFDFLSHLPESLHTFFFLFDDVGVPSDYRHMEGFGVNTYTFVSAAGKAQYVKFHWKPTCGVRCILTDEEAALVGGRNHSHATQDLYDSIAAGSFPEWTLYVQVMDPDTEEQYDFDPLDDTKTWPEDLLPLRPVGRLVLDRNVDNFFN... | circadian rhythm cold acclimation hydrogen peroxide catabolic process response to auxin response to hydrogen peroxide response to oxidative stress response to reactive oxygen species response to xenobiotic stimulus cytoplasm; mitochondrion; peroxisome; plasma membrane catalase activity heme binding metal ion binding Ze... |
cytoplasmic translation maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal large subunit biogenesis rRNA processing translation | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; focal adhesion; membrane; nucleolus; nucleus; postsynaptic density; ribonucleoprotein complex | DNA binding identical protein binding mRNA binding RNA binding structural constituent of ribosome | Homo sapiens | 3D-structure Acetylation Cytoplasm Direct protein sequencing Phosphoprotein Reference proteome Repeat Ribonucleoprotein Ribosomal protein RNA-binding | MEGVEEKKKE | MEGVEEKKKEVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQINRLIRRMN | cytoplasmic translation maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal large subunit biogenesis rRNA processing translation cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; focal adhesion; membrane; nucleolus; nucleus; postsynaptic density; r... |
bile acid and bile salt transport bile acid biosynthetic process bile acid signaling pathway cellular response to cholesterol cellular response to glucose stimulus cholesterol catabolic process cholesterol homeostasis negative regulation of collagen biosynthetic process negative regulation of fatty acid biosynthetic pr... | endoplasmic reticulum membrane; intracellular membrane-bounded organelle | 24-hydroxycholesterol 7alpha-hydroxylase activity cholesterol 7-alpha-monooxygenase activity heme binding iron ion binding | Rattus norvegicus | Cholesterol metabolism Direct protein sequencing Endoplasmic reticulum Heme Iron Lipid metabolism Membrane Metal-binding Microsome Monooxygenase Oxidoreductase Reference proteome Steroid metabolism Sterol metabolism Transmembrane Transmembrane helix | MMTISLIWGI | MMTISLIWGIAVLVSCCIWFIVGIRRRKAGEPPLENGLIPYLGCALKFGSNPLEFLRANQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSIDPNDGNTTENINNTFTKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSNAWVTEGMYAFCYRVMFEAGYLTLFGRDISKTDTQKALILNNLDNFKQFDQVFPALVAGLPIHLFKTAHKAREKLAEGLKHKNLCVRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLAILWASQANTIPATFWSLFQMIRSPEAMKAASEEVSGALQ... | bile acid and bile salt transport bile acid biosynthetic process bile acid signaling pathway cellular response to cholesterol cellular response to glucose stimulus cholesterol catabolic process cholesterol homeostasis negative regulation of collagen biosynthetic process negative regulation of fatty acid biosynthetic pr... |
adenylate cyclase-activating adrenergic receptor signaling pathway cell-cell signaling phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of heart rate by epinephrine-norepinephrine positive regulation of MAPK cascade po... | caveola; cytoplasm; nuclear membrane; nucleus; plasma membrane | alpha1-adrenergic receptor activity protein heterodimerization activity | Bos taurus | Cell membrane Cytoplasm Disulfide bond G-protein coupled receptor Glycoprotein Lipoprotein Membrane Nucleus Palmitate Phosphoprotein Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MVFLSGNASD | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFRPSETVFKIAFWLGYLNSC... | adenylate cyclase-activating adrenergic receptor signaling pathway cell-cell signaling phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of heart rate by epinephrine-norepinephrine positive regulation of MAPK cascade po... |
fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell | host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | metal ion binding | Tacaribe virus | Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endoplasmic reticulum Host Golgi apparatus Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Transmembrane Transmembran... | MGQFISFMQE | MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTKFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSEVNLTSINLTRSIDVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGEQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNEAPGGYCLEKWMLVASELKCFGNTAIAKCNQNHDSEFCDMLRLFDY... | fusion of virus membrane with host endosome membrane receptor-mediated endocytosis of virus by host cell virion attachment to host cell host cell endoplasmic reticulum membrane; host cell Golgi membrane; host cell plasma membrane; membrane; viral envelope; virion membrane metal ion binding Tacaribe virus Disulfide bon... |
tetrahydrofolate interconversion tetrahydrofolate metabolic process | mitochondrion | magnesium ion binding methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity phosphate ion binding | Mus musculus | Acetylation Direct protein sequencing Hydrolase Isopeptide bond Magnesium Mitochondrion Multifunctional enzyme NAD NADP One-carbon metabolism Oxidoreductase Reference proteome Transit peptide Ubl conjugation | MASVSLLSAL | MASVSLLSALAVRLLRPTHGCHPRLQPFHLAAVRNEAVVISGRKLAQQIKQEVQQEVEEWVASGNKRPHLSVILVGDNPASHSYVLNKTRAAAEVGINSETIVKPASVSEEELLNSIRKLNNDENVDGLLVQLPLPEHIDERKVCNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVQDPVTAKPKLVGDVDFEGVKKKAGYITPVPGGVGPMTVAML... | tetrahydrofolate interconversion tetrahydrofolate metabolic process mitochondrion magnesium ion binding methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity phosphate ion binding Mus musculus Acetylation Direct ... |
adiponectin-activated signaling pathway fatty acid metabolic process fatty acid transport lipid biosynthetic process long-chain fatty acid import into cell long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process positive regulation of cold-induced thermogenesis positive regulation of long... | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial outer membrane; mitochondrion; peroxisomal membrane | acetate-CoA ligase activity arachidonate-CoA ligase activity ATP binding long-chain fatty acid-CoA ligase activity oleoyl-CoA ligase activity phytanate-CoA ligase activity pristanate-CoA ligase activity protein serine/threonine kinase activator activity | Rattus norvegicus | Acetylation ATP-binding Direct protein sequencing Endoplasmic reticulum Fatty acid metabolism Glycoprotein Ligase Lipid metabolism Magnesium Membrane Microsome Mitochondrion Mitochondrion outer membrane Nitration Nucleotide-binding Peroxisome Phosphoprotein Reference proteome Signal-anchor Transmembrane Transmembrane h... | MEVHELFRYF | MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEVTGTTEGVRRSAVLEDDKLLLYYYDDVRTMYDGFQRGIQVSNDGPCLGSRKPNQPYEWISYKQVAEMAECIGSALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCFTYSMVVVPLYDTLGTDAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVERGQKCGVEIIGLKALEDLGRVNRTKPKPPEPEDLAIICFTSGTTGNPKGAMVTHQNIMNDCSGFIKATESAFIASPEDVLISF... | adiponectin-activated signaling pathway fatty acid metabolic process fatty acid transport lipid biosynthetic process long-chain fatty acid import into cell long-chain fatty acid metabolic process long-chain fatty-acyl-CoA biosynthetic process positive regulation of cold-induced thermogenesis positive regulation of long... |
chorion-containing eggshell formation egg chorion assembly response to starvation | egg chorion; extracellular region; nucleus | cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific structural constituent of egg chorion | Drosophila melanogaster | Alternative splicing Direct protein sequencing Reference proteome Repeat Secreted Signal | MRLFSLLPLL | MRLFSLLPLLALLVVQAAGQSEVTSDDPATDAGSTTNSTTDTKPRIPSQDEILGQMPSINPIRTGNPQMDAFYMMFPALGSLLKWGSLFPAYSILGAIPDNLQPTAAASKVVLVLADDATAKTRVARQNPPPNPLGQLMNWPALPQDFQLPSMDLGPQVGSFLAQLPAMPTVPGLLGAAAPVPAPAPAPAAAPPPAPAPAADPPAAPVPDAPQPAILGQAALQNAFTFFNPANFDASSLLGQSVPTFAPPNLDFVAQMQRQFFPGMTPAQPAAAGTDAQASDISEVRVRPEDPYSQEAQMKIKSALEMEQERQQQAQVKD... | chorion-containing eggshell formation egg chorion assembly response to starvation egg chorion; extracellular region; nucleus cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific structural constituent of egg chorion Drosophila melanogaster Alternative... |
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