Biological Process stringlengths 7 1.01k | Cellular Component stringlengths 6 867 | Molecular Function stringlengths 11 871 | Organism stringlengths 8 73 | Keywords stringlengths 1 810 | Sequence 10 stringlengths 5 10 | Sequence stringlengths 5 1.02k | Combined stringlengths 136 3.91k |
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cell division cell morphogenesis division septum assembly regulation of cell division regulation of division septum assembly | cell pole; cytosol | identical protein binding | Escherichia coli | 3D-structure Cell cycle Cell division Reference proteome Septation | MSNTPIELKG | MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLKHAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGKEKAPRPAPTPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARLQLVENALTVQPLN | cell division cell morphogenesis division septum assembly regulation of cell division regulation of division septum assembly cell pole; cytosol identical protein binding Escherichia coli 3D-structure Cell cycle Cell division Reference proteome Septation MSNTPIELKG MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLKHAPVVLNVSAL... |
glycerophospholipid biosynthetic process phosphatidylglycerol biosynthetic process phospholipid catabolic process phospholipid dephosphorylation response to magnesium ion | plasma membrane | lipid phosphatase activity metal ion binding phosphatidylglycerophosphatase activity | Escherichia coli | Cell inner membrane Cell membrane Hydrolase Lipid degradation Lipid metabolism Magnesium Membrane Metal-binding Phospholipid degradation Phospholipid metabolism Reference proteome Transmembrane Transmembrane helix | MTILPRHKDV | MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAAIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITLMALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIGHHWPLGILS | glycerophospholipid biosynthetic process phosphatidylglycerol biosynthetic process phospholipid catabolic process phospholipid dephosphorylation response to magnesium ion plasma membrane lipid phosphatase activity metal ion binding phosphatidylglycerophosphatase activity Escherichia coli Cell inner membrane Cell membra... |
amyloid fibril formation cytokine-mediated signaling pathway heart morphogenesis heart trabecula formation muscle contraction negative regulation of phosphoprotein phosphatase activity negative regulation of protein phosphorylation negative regulation of release of sequestered calcium ion into cytosol negative regulati... | cytoplasm; cytoplasmic side of membrane; cytosol; extracellular exosome; membrane; ryanodine receptor complex; sarcoplasmic reticulum; sarcoplasmic reticulum membrane; Z disc | activin binding calcium channel inhibitor activity FK506 binding peptidyl-prolyl cis-trans isomerase activity protein homodimerization activity SMAD binding transmembrane transporter binding | Bos taurus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Isomerase Membrane Reference proteome Rotamase Sarcoplasmic reticulum | MGVQVETISP | MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFVLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPNATLIFDVELLKLE | amyloid fibril formation cytokine-mediated signaling pathway heart morphogenesis heart trabecula formation muscle contraction negative regulation of phosphoprotein phosphatase activity negative regulation of protein phosphorylation negative regulation of release of sequestered calcium ion into cytosol negative regulati... |
anaerobic respiration heme transport mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport transmembrane transport | mitochondrial inner membrane; mitochondrion | ATP:ADP antiporter activity identical protein binding | Saccharomyces cerevisiae | 3D-structure Antiport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MSSDAKQQET | MSSDAKQQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKEEGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKFK | anaerobic respiration heme transport mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport transmembrane transport mitochondrial inner membrane; mitochondrion ATP:ADP antiporter activity identical protein binding Saccharomyces cerevisiae 3D-structure Antiport Membrane Mitochondrion Mitoch... |
ADP transport aerobic respiration anaerobic respiration apoptotic process ATP transport heme transport mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport mitochondrial transport transmembrane transport | membrane; mitochondrial inner membrane; mitochondrion | ATP:ADP antiporter activity | Saccharomyces cerevisiae | 3D-structure Antiport Membrane Mitochondrion Mitochondrion inner membrane Reference proteome Repeat Transmembrane Transmembrane helix Transport | MSSNAQVKTP | MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK | ADP transport aerobic respiration anaerobic respiration apoptotic process ATP transport heme transport mitochondrial ADP transmembrane transport mitochondrial ATP transmembrane transport mitochondrial transport transmembrane transport membrane; mitochondrial inner membrane; mitochondrion ATP:ADP antiporter activity Sac... |
autophagosome assembly insulin catabolic process insulin receptor recycling lipoprotein catabolic process positive regulation of apoptotic process protein catabolic process proteolysis regulation of establishment of protein localization | collagen-containing extracellular matrix; endosome lumen; endosome membrane; extracellular space; GABA-ergic synapse; lysosomal membrane; lysosome; melanosome; membrane raft; mitochondrion; presynaptic endosome | aspartic-type endopeptidase activity aspartic-type peptidase activity endopeptidase activity hydrolase activity peptidase activity peptide binding | Mus musculus | Aspartyl protease Disulfide bond Glycoprotein Hydrolase Lysosome Protease Reference proteome Secreted Signal Zymogen | MKTPGVLLLI | MKTPGVLLLILGLLASSSFAIIRIPLRKFTSIRRTMTEVGGSVEDLILKGPITKYSMQSSPKTTEPVSELLKNYLDAQYYGDIGIGTPPQCFTVVFDTGSSNLWVPSIHCKILDIACWVHHKYNSDKSSTYVKNGTSFDIHYGSGSLSGYLSQDTVSVPCKSDQSKARGIKVEKQIFGEATKQPGIVFVAAKFDGILGMGYPHISVNNVLPVFDNLMQQKLVDKNIFSFYLNRDPEGQPGGELMLGGTDSKYYHGELSYLNVTRKAYWQVHMDQLEVGNELTLCKGGCEAIVDTGTSLLVGPVEEVKELQKAIGAVPLIQ... | autophagosome assembly insulin catabolic process insulin receptor recycling lipoprotein catabolic process positive regulation of apoptotic process protein catabolic process proteolysis regulation of establishment of protein localization collagen-containing extracellular matrix; endosome lumen; endosome membrane; extrac... |
adult heart development ATP transport blood vessel morphogenesis bone development bone remodeling cell communication cell communication by electrical coupling cell-cell signaling embryonic heart tube development epithelial cell maturation heart development heart looping in utero embryonic development microtubule-based ... | apical plasma membrane; cell junction; connexin complex; cytoplasm; early endosome; endoplasmic reticulum; fascia adherens; gap junction; intercalated disc; late endosome; lysosome; mitochondrion; multivesicular body; plasma membrane | gap junction channel activity gap junction hemi-channel activity PDZ domain binding SH3 domain binding tubulin binding | Bos taurus | Acetylation Cell junction Cell membrane Disulfide bond Endoplasmic reticulum Gap junction Isopeptide bond Membrane Phosphoprotein Reference proteome S-nitrosylation Transmembrane Transmembrane helix Ubl conjugation | MGDWSALGKL | MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVVAQTDGANVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGKSDPYHTTTGPLSPSKDCGSPKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNR... | adult heart development ATP transport blood vessel morphogenesis bone development bone remodeling cell communication cell communication by electrical coupling cell-cell signaling embryonic heart tube development epithelial cell maturation heart development heart looping in utero embryonic development microtubule-based ... |
cell population proliferation cochlea morphogenesis cranial ganglion formation gene expression insulin-like growth factor receptor signaling pathway negative regulation of apoptotic process negative regulation of insulin secretion negative regulation of neuron apoptotic process negative regulation of release of cytochr... | extracellular space | growth factor activity hormone activity insulin-like growth factor receptor binding | Gallus gallus | Direct protein sequencing Disulfide bond Growth factor Reference proteome Secreted Signal | MEKINSLSTQ | MEKINSLSTQLVKCCFCDFLKVKMHTVSYIHFFYLGLCLLTLTSSAAAGPETLCGAELVDALQFVCGDRGFYFSKPTGYGSSSRRLHHKGIVDECCFQSCDLRRLEMYCAPIKPPKSARSVRAQRHTDMPKAQKEVHLKNTSRGNTGNRNYRM | cell population proliferation cochlea morphogenesis cranial ganglion formation gene expression insulin-like growth factor receptor signaling pathway negative regulation of apoptotic process negative regulation of insulin secretion negative regulation of neuron apoptotic process negative regulation of release of cytochr... |
microtubule-based process | cytoplasm; microtubule | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Paracentrotus lividus | Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding | MRECISIHVG | MRECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTVGKELIDIVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFSSLLMERLSVDYGKKSKLEFAVYPAPQISTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVSEITNACFEPANQMVKCDPRHGKYMACCLLYR... | microtubule-based process cytoplasm; microtubule GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Paracentrotus lividus Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding MRECISIHVG MRECISIHVGQAGVQMGNACWELYCLEHGIQPDGQMPS... |
viral RNA genome packaging | helical viral capsid; host cell cytoplasm; ribonucleoprotein complex; viral nucleocapsid | RNA binding | Zaire ebolavirus | 3D-structure Acetylation Capsid protein Helical capsid protein Host cytoplasm Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding Virion | MDSRPQKIWM | MDSRPQKIWMAPSLTESDMDYHKILTAGLSVQQGIVRQRVIPVYQVNNLEEICQLIIQAFEAGVDFQESADSFLLMLCLHHAYQGDYKLFLESGAVKYLEGHGFRFEVKKRDGVKRLEELLPAVSSGKNIKRTLAAMPEEETTEANAGQFLSFASLFLPKLVVGEKACLEKVQRQIQVHAEQGLIQYPTAWQSVGHMMVIFRLMRTNFLIKFLLIHQGMHMVAGHDANDAVISNSVAQARFSGLLIVKTVLDHILQKTERGVRLHPLARTAKVKNEVNSFKAALSSLAKHGEYAPFARLLNLSGVNNLEHGLFPQLSAIA... | viral RNA genome packaging helical viral capsid; host cell cytoplasm; ribonucleoprotein complex; viral nucleocapsid RNA binding Zaire ebolavirus 3D-structure Acetylation Capsid protein Helical capsid protein Host cytoplasm Phosphoprotein Reference proteome Ribonucleoprotein RNA-binding Virion MDSRPQKIWM MDSRPQKIWMAPS... |
response to oxidative stress | cytoplasm; cytosol; intercellular bridge; mitotic spindle | electron transfer activity glutathione peroxidase activity phospholipid-hydroperoxide glutathione peroxidase activity | Homo sapiens | 3D-structure Cytoplasm Oxidoreductase Peroxidase Reference proteome Selenocysteine | MAFIAKSFYD | MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI | response to oxidative stress cytoplasm; cytosol; intercellular bridge; mitotic spindle electron transfer activity glutathione peroxidase activity phospholipid-hydroperoxide glutathione peroxidase activity Homo sapiens 3D-structure Cytoplasm Oxidoreductase Peroxidase Reference proteome Selenocysteine MAFIAKSFYD MAFIAKSF... |
cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle assembly intermediate-density lipoprotein particle clearance lipoprotein biosynthetic process melanosome organization triglyceride-rich lipoprotein particle clearance very-low-density lipoprotein particle clearance | chylomicron; extracellular exosome; extracellular matrix; high-density lipoprotein particle; intermediate-density lipoprotein particle; low-density lipoprotein particle; multivesicular body, internal vesicle; very-low-density lipoprotein particle | amyloid-beta binding heparan sulfate proteoglycan binding heparin binding identical protein binding lipid binding low-density lipoprotein particle receptor binding peptide binding protein homodimerization activity | Oryctolagus cuniculus | Chylomicron Endosome Extracellular matrix Glycoprotein HDL Heparin-binding Lipid transport Lipid-binding Oxidation Phosphoprotein Reference proteome Repeat Secreted Signal Transport VLDL | MKVWWAVLAA | MKVWWAVLAAAILAGCRAQTEQEVEVPEQARWKAGQPWELALGRFWDYLRWVQSLSDQVQEELLSSQVTQELTMLMEETMKEVKAYKSELEEQLSPMAQEHRARLSKELQVAGALEADMEDVCNRLAQYRGEAQAMLGQSTEELARAFSSHLRKLRKRLLRDAEDLQKRMAVYGAGAREGAERGVSAVRERLGSRLERGRLRVATVGTLAGRPLRERAQAWGERLRGHLEEVGSRARDRLNEVREQVEEVRVKVEEQAPQMRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKLQAAMPSKAPAAAPIENQ | cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle assembly intermediate-density lipoprotein particle clearance lipoprotein biosynthetic process melanosome organization triglyceride-rich lipoprotein particle clearance very-low-density lipoprotein particle clearance chylomicron; extracell... |
microtubule-based process | cytoplasm; microtubule | GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton | Oncorhynchus mykiss | Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding | MRECISIHVG | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRVRKLSDQCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEMLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYR... | microtubule-based process cytoplasm; microtubule GTP binding hydrolase activity metal ion binding structural constituent of cytoskeleton Oncorhynchus mykiss Acetylation Cytoplasm Cytoskeleton GTP-binding Hydrolase Magnesium Metal-binding Microtubule Nucleotide-binding MRECISIHVG MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSD... |
chorion micropyle formation dorsal appendage formation dorsal closure imaginal disc fusion, thorax closure JNK cascade modulation by host of viral genome replication negative regulation of antimicrobial humoral response positive regulation of transcription by RNA polymerase II R3/R4 cell fate commitment regulation of c... | cytosol; nucleoplasm; nucleus; transcription factor AP-1 complex; transcription regulator complex | DNA-binding transcription factor activity, RNA polymerase II-specific protein heterodimerization activity RNA polymerase II cis-regulatory region sequence-specific DNA binding | Drosophila melanogaster | Activator Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MKTPVSAAAN | MKTPVSAAANLSIQNAGSSGATAIQIIPKTEPVGEEGPMSLDFQSPNLNTSTPNPNKRPGSLDLNSKSAKNKRIFAPLVINSPDLSSKTVNTPDLEKILLSNNLMQTPQPGKVFPTKAGPVTVEQLDFGRGFEEALHNLHTNSQAFPSANSAANSAANNTTAAAMTAVNNGISGGTFTYTNMTEGFSVIKDEPVNQASSPTVNPIDMEAQEKIKLERKRQRNRVAASKCRKRKLERISKLEDRVKVLKGENVDLASIVKNLKDHVAQLKQQVMEHIAAGCTVPPNSTDQ | chorion micropyle formation dorsal appendage formation dorsal closure imaginal disc fusion, thorax closure JNK cascade modulation by host of viral genome replication negative regulation of antimicrobial humoral response positive regulation of transcription by RNA polymerase II R3/R4 cell fate commitment regulation of c... |
defense response to bacterium granzyme-mediated programmed cell death signaling pathway killing of cells of another organism natural killer cell mediated cytotoxicity negative regulation of translation neuron apoptotic process positive regulation of necroptotic process protein maturation proteolysis involved in protein... | cytolytic granule; cytoplasm; early endosome; extracellular space; intracellular membrane-bounded organelle | serine-type endopeptidase activity serine-type peptidase activity | Rattus norvegicus | 3D-structure Apoptosis Cytolysis Direct protein sequencing Disulfide bond Hydrolase Lysosome Protease Reference proteome Secreted Serine protease Signal Zymogen | MKLLLLLLSF | MKLLLLLLSFSLAPKTEAGEIIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKINVTLGAHNIKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPGDVCYVAGWGKLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQNDGSTPRAFTKVSTFLSWIKKTMKKS | defense response to bacterium granzyme-mediated programmed cell death signaling pathway killing of cells of another organism natural killer cell mediated cytotoxicity negative regulation of translation neuron apoptotic process positive regulation of necroptotic process protein maturation proteolysis involved in protein... |
cell morphogenesis involved in neuron differentiation dopamine metabolic process L-phenylalanine metabolic process nitric oxide biosynthetic process norepinephrine metabolic process pteridine metabolic process regulation of multicellular organism growth response to organic substance serotonin metabolic process tetrahyd... | cytoplasm | protein homodimerization activity sepiapterin reductase activity | Rattus norvegicus | Acetylation Cytoplasm Direct protein sequencing NADP Oxidoreductase Phosphoprotein Reference proteome | MEGGRLGCAV | MEGGRLGCAVCVLTGASRGFGRALAPQLAGLLSPGSVLLLSARSDSMLRQLKEELCTQQPGLQVVLAAADLGTESGVQQLLSAVRELPRPERLQRLLLINNAGTLGDVSKGFLNINDLAEVNNYWALNLTSMLCLTTGTLNAFSNSPGLSKTVVNISSLCALQPFKGWGLYCAGKAARDMLYQVLAVEEPSVRVLSYAPGPLDTNMQQLARETSMDPELRSRLQKLNSEGELVDCGTSAQKLLSLLQRDTFQSGAHVDFYDI | cell morphogenesis involved in neuron differentiation dopamine metabolic process L-phenylalanine metabolic process nitric oxide biosynthetic process norepinephrine metabolic process pteridine metabolic process regulation of multicellular organism growth response to organic substance serotonin metabolic process tetrahyd... |
cellular response to leukemia inhibitory factor circadian rhythm one-carbon metabolic process protein heterooligomerization protein hexamerization response to cAMP response to hormone response to light stimulus response to xenobiotic stimulus S-adenosylmethionine biosynthetic process | cytosol; methionine adenosyltransferase complex | amino acid binding ATP binding identical protein binding metal ion binding methionine adenosyltransferase activity small molecule binding | Rattus norvegicus | Acetylation ATP-binding Isopeptide bond Magnesium Metal-binding Nucleotide-binding One-carbon metabolism Phosphoprotein Potassium Reference proteome Transferase Ubl conjugation | MNGQLNGFHE | MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQINDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVIPIRVHTIVISVQHDEEVCLDEMRDALKEKLIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSY... | cellular response to leukemia inhibitory factor circadian rhythm one-carbon metabolic process protein heterooligomerization protein hexamerization response to cAMP response to hormone response to light stimulus response to xenobiotic stimulus S-adenosylmethionine biosynthetic process cytosol; methionine adenosyltransfe... |
urea catabolic process | cytoplasm | nickel cation binding urease activity | Klebsiella aerogenes | 3D-structure Cytoplasm Hydrolase Metal-binding Nickel | MSNISRQAYA | MSNISRQAYADMFGPTVGDKVRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLAADCVDLVLTNALIVDHWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICPQQAEEALVSGVTTMVGGGTGPAAGTHATTCTPGPWYISRMLQAADSLPVNIGLLGKGNVSQPDALREQVAAGVIGLKIHEDWGATPAAIDCALTVADEMDIQVALHSDTLNESGFVEDTLAAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTLNTIDEHLDMLMVCH... | urea catabolic process cytoplasm nickel cation binding urease activity Klebsiella aerogenes 3D-structure Cytoplasm Hydrolase Metal-binding Nickel MSNISRQAYA MSNISRQAYADMFGPTVGDKVRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLAADCVDLVLTNALIVDHWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGAATEVIAAEGKIVTAGGIDTHIHWICPQQAEEALVSGVTTMVGGGTGPAA... |
vitamin D3 metabolic process | cytoplasm | heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | Streptomyces griseolus | 3D-structure Cytoplasm Direct protein sequencing Heme Iron Metal-binding Monooxygenase Oxidoreductase | MTDTATTPQT | MTDTATTPQTTDAPAFPSNRSCPYQLPDGYAQLRDTPGPLHRVTLYDGRQAWVVTKHEAARKLLGDPRLSSNRTDDNFPATSPRFEAVRESPQAFIGLDPPEHGTRRRMTISEFTVKRIKGMRPEVEEVVHGFLDEMLAAGPTADLVSQFALPVPSMVICRLLGVPYADHEFFQDASKRLVQSTDAQSALTARNDLAGYLDGLITQFQTEPGAGLVGALVADQLANGEIDREELISTAMLLLIAGHETTASMTSLSVITLLDHPEQYAALRADRSLVPGAVEELLRYLAIADIAGGRVATADIEVEGHLIRAGEGVIVVN... | vitamin D3 metabolic process cytoplasm heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen Streptomyces griseolus3D-structure Cytoplasm Direct protein sequencing Heme Iron Metal... |
peptidyl-serine phosphorylation regulation of cell cycle response to hermaphrodite contact vulval location Wnt signaling pathway | axon; cilium; cytosol; dendrite; neuronal cell body; non-motile cilium; nucleus; perikaryon; protein kinase CK2 complex | ATP binding protein kinase activity protein serine kinase activity protein serine/threonine kinase activity | Caenorhabditis elegans | ATP-binding Behavior Cell projection Cilium Kinase Nucleotide-binding Reference proteome Serine/threonine-protein kinase Transferase Wnt signaling pathway | MPPIPSRARV | MPPIPSRARVYAEVNPSRPREYWDYEAHMIEWGQIDDYQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIKREIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQTLSDYDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVRVASRYFKGPELLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMGH... | peptidyl-serine phosphorylation regulation of cell cycle response to hermaphrodite contact vulval location Wnt signaling pathway axon; cilium; cytosol; dendrite; neuronal cell body; non-motile cilium; nucleus; perikaryon; protein kinase CK2 complex ATP binding protein kinase activity protein serine kinase activity prot... |
arginine biosynthetic process via ornithine lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate | cytoplasm | identical protein binding N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity pyridoxal phosphate binding succinyldiaminopimelate transaminase activity | Escherichia coli | Amino-acid biosynthesis Aminotransferase Arginine biosynthesis Cytoplasm Direct protein sequencing Lysine biosynthesis Pyridoxal phosphate Reference proteome Transferase | MAIEQTAITR | MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD... | arginine biosynthetic process via ornithine lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate cytoplasm identical protein binding N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity pyridoxal phosphate binding succinyldiaminopimelate transaminase activity Escherichia col... |
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling positive regulation of neutrophil chemotaxis regulation of apoptotic process response to ATP response to cytokine | cell surface; external side of plasma membrane; extracellular space; plasma membrane | calcium ion binding cell adhesion molecule binding glycolipid binding oligosaccharide binding protease binding sialic acid binding | Mus musculus | Calcium Cell adhesion Cell membrane Disulfide bond EGF-like domain Glycoprotein Lectin Membrane Metal-binding Reference proteome Repeat Signal Sushi Transmembrane Transmembrane helix | MVFPWRCEGT | MVFPWRCEGTYWGSRNILKLWVWTLLCCDFLIHHGTHCWTYHYSEKPMNWENARKFCKQNYTDLVAIQNKREIEYLENTLPKSPYYYWIGIRKIGKMWTWVGTNKTLTKEAENWGAGEPNNKKSKEDCVEIYIKRERDSGKWNDDACHKRKAALCYTASCQPGSCNGRGECVETINNHTCICDAGYYGPQCQYVVQCEPLEAPELGTMDCIHPLGNFSFQSKCAFNCSEGRELLGTAETQCGASGNWSSPEPICQVVQCEPLEAPELGTMDCIHPLGNFSFQSKCAFNCSEGRELLGTAETQCGASGNWSSPEPICQETN... | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling positive regulation of neutrophil chemotaxis regulation of apoptotic process response to ATP response to cytokine cell surface; exte... |
adenylate cyclase-activating G protein-coupled receptor signaling pathway antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide chemokine-mediated signaling pathway chemotaxis defense response to virus inflammatory response killing of cells of another organism n... | external side of plasma membrane; extracellular space | chemokine activity CXCR chemokine receptor binding CXCR3 chemokine receptor binding | Mus musculus | Cytokine Disulfide bond Glycoprotein Inflammatory response Reference proteome Secreted Signal | MKSAVLFLLG | MKSAVLFLLGIIFLEQCGVRGTLVIRNARCSCISTSRGTIHYKSLKDLKQFAPSPNCNKTEIIATLKNGDQTCLDPDSANVKKLMKEWEKKISQKKKQKRGKKHQKNMKNRKPKTPQSRRRSRKTT | adenylate cyclase-activating G protein-coupled receptor signaling pathway antimicrobial humoral immune response mediated by antimicrobial peptide cellular response to lipopolysaccharide chemokine-mediated signaling pathway chemotaxis defense response to virus inflammatory response killing of cells of another organism n... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane virion attachment to host cell | extracellular region; host cell endoplasmic reticulum membrane; membrane; viral envelope; viral nucleocapsid; virion membrane | protein dimerization activity | Dengue virus type 2 | 3D-structure Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host endoplasmic reticulum Host membrane Host-virus interaction Membrane Secreted Suppressor of RNA... | SAGMIIMLIP | SAGMIIMLIPTVMAFHLTTRNGEPHMIVSRQEKGKSLLFKTEDGVNMCTLMAMDLGELCEDTITYKCPLLRQNEPEDIDCWCNSTSTWVTYGTCTTTGEHRREKRSVALVPHVGMGLETRTETWMSSEGAWKHAQRIEIWILRHPGFTIMAAILAYTIGTTHFQRALIFILLTAVAPSMTMRCIGISNRDFVEGVSGGSWVDIVLEHGSCVTTMAKNKPTLDFELIKTEAKQPATLRKYCIEAKLTNTTTESRCPTQGEPSLNEEQDKRFVCKHSMVDRGWGNGCGLFGKGGIVTCAMFTCKKNMEGKVVQPENLEYTIV... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane virion attachment to host cell extracellular region; host cell endoplasmic reticulum membrane; membrane; viral envelope; viral nucleocapsid; virion membrane protein dimerization activity Dengue virus type 2 3D-str... |
suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway | cytoplasm | peptidase inhibitor activity protein sequestering activity protein serine/threonine kinase inhibitor activity RNA binding | Vaccinia virus ) | 3D-structure Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Inhibition of host PKR by virus Reference proteome RNA-binding Viral immunoevasion | MLAFCYSLPN | MLAFCYSLPNAGDVIKGRVYEKDYALYIYLFDYPHFEAILAESVKMHMDRYVEYRDKLVGKTVKVKVIRVDYTKGYIDVNYKRMCRHQ | suppression by virus of host PKR signaling suppression by virus of host type I interferon-mediated signaling pathway cytoplasm peptidase inhibitor activity protein sequestering activity protein serine/threonine kinase inhibitor activity RNA binding Vaccinia virus )3D-structure Host-virus interaction Inhibition of hos... |
androgen biosynthetic process androgen catabolic process bone development cell differentiation cellular response to cAMP cellular response to dexamethasone stimulus cellular response to epinephrine stimulus cellular response to estradiol stimulus cellular response to growth factor stimulus cellular response to insulin ... | cell body fiber; endoplasmic reticulum membrane; neuronal cell body; perinuclear region of cytoplasm | 3-oxo-5-alpha-steroid 4-dehydrogenase activity 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) amide binding electron transfer activity NADPH binding | Homo sapiens | Differentiation Endoplasmic reticulum Lipid metabolism Membrane Microsome NADP Oxidoreductase Reference proteome Sexual differentiation Transmembrane Transmembrane helix | MATATGVAEE | MATATGVAEERLLAALAYLQCAVGCAVFARNRQTNSVYGRHALPSHRLRVPARAAWVVQELPSLALPLYQYASESAPRLRSAPNCILLAMFLVHYGHRCLIYPFLMRGGKPMPLLACTMAIMFCTCNGYLQSRYLSHCAVYADDWVTDPRFLIGFGLWLTGMLINIHSDHILRNLRKPGDTGYKIPRGGLFEYVTAANYFGEIMEWCGYALASWSVQGAAFAFFTFCFLSGRAKEHHEWYLRKFEEYPKFRKIIIPFLF | androgen biosynthetic process androgen catabolic process bone development cell differentiation cellular response to cAMP cellular response to dexamethasone stimulus cellular response to epinephrine stimulus cellular response to estradiol stimulus cellular response to growth factor stimulus cellular response to insulin ... |
lipid metabolic process negative regulation of phospholipid biosynthetic process nuclear envelope organization regulation of phospholipid biosynthetic process reticulophagy sporulation resulting in formation of a cellular spore | endoplasmic reticulum; endoplasmic reticulum membrane; membrane; Nem1-Spo7 phosphatase complex; nuclear membrane | protein phosphatase regulator activity | Saccharomyces cerevisiae | Endoplasmic reticulum Lipid metabolism Membrane Nucleus Reference proteome Sporulation Transmembrane Transmembrane helix | MEPESIGDVG | MEPESIGDVGNHAQDDSASIVSGPRRRSTSKTSSAKNIRNSSNISPASMIFRNLLILEDDLRRQAHEQKILKWQFTLFLASMAGVGAFTFYELYFTSDYVKGLHRVILQFTLSFISITVVLFHISGQYRRTIVIPRRFFTSTNKGIRQFNVKLVKVQSTWDEKYTDSVRFVSRTIAYCNIYCLKKFLWLKDDNAIVKFWKSVTIQSQPRIGAVDVKLVLNPRAFSAEIREGWEIYRDEFWAREGARRRKQAHELRPKSE | lipid metabolic process negative regulation of phospholipid biosynthetic process nuclear envelope organization regulation of phospholipid biosynthetic process reticulophagy sporulation resulting in formation of a cellular spore endoplasmic reticulum; endoplasmic reticulum membrane; membrane; Nem1-Spo7 phosphatase compl... |
invasive growth in response to glucose limitation negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of pseudohyphal growth positive regulation of transcription by RNA polymerase II pseudohyphal growth regulation of filamentous growth regulat... | nucleus; Tec1p-Ste12p-Dig1p complex; transcription regulator complex | DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding | Saccharomyces cerevisiae | Acetylation Activator DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MSLKEDDFGK | MSLKEDDFGKDNSRNIESYTGRIFDVYIQKDSYSQSALDDMFPEAVVSTAACVKNEAEDNINLIDTHPQFELVNTGLGAKSDDLKSPSAKATFTDKQRKNEVPNISVSNYFPGQSSETSSTTESWTIGCDKWSEKVEEAFLEALRLIMKNGTTKIKIRNANFGRNELISLYIKHKTNEFRTKKQISSHIQVWKKTIQNKIKDSLTLSSKEKELLHLIEHGAEQTTENSNLFYDIFEEIIDSLPSVSDSGSLTPKNLYVSNNSSGLSVHSKLLTPITASNEKKIENFIKTNAASQAKTPLIYAKHIYENIDGYKCVPSKRP... | invasive growth in response to glucose limitation negative regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of pseudohyphal growth positive regulation of transcription by RNA polymerase II pseudohyphal growth regulation of filamentous growth regulat... |
immune system process negative regulation of inflammatory response to antigenic stimulus proteasomal protein catabolic process ubiquitin-dependent protein catabolic process | centrosome; cytoplasm; nucleoplasm; nucleus; proteasome complex; proteasome core complex; proteasome core complex, alpha-subunit complex | lipopolysaccharide binding | Rattus norvegicus | 3D-structure Acetylation Cytoplasm Direct protein sequencing Glycoprotein Immunity Isopeptide bond Nucleus Phosphoprotein Proteasome Reference proteome Ubl conjugation | MFRNQYDNDV | MFRNQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHVFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMQCNLDELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEERPQRKAQPSQAADEPAEKADEPMEH | immune system process negative regulation of inflammatory response to antigenic stimulus proteasomal protein catabolic process ubiquitin-dependent protein catabolic process centrosome; cytoplasm; nucleoplasm; nucleus; proteasome complex; proteasome core complex; proteasome core complex, alpha-subunit complex lipopolysa... |
aflatoxin metabolic process cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid metabolic process lipoprotein biosynthetic process lipoprotein metabolic process phosphatidylcholine biosynthetic process phosphatidylcholine metabolic process phosp... | extracellular space; high-density lipoprotein particle | 1-alkyl-2-acetylglycerophosphocholine esterase activity apolipoprotein A-I binding phosphatidylcholine-sterol O-acyltransferase activity phospholipase A2 activity platelet-activating factor acetyltransferase activity sterol esterase activity | Rattus norvegicus | Acyltransferase Cholesterol metabolism Disulfide bond Glycoprotein Hydrolase Lipid metabolism Reference proteome Secreted Signal Steroid metabolism Sterol metabolism Transferase | MGLPGSPWQW | MGLPGSPWQWVLLLLGLLLPPATSFWLLNVLFPPHTTPKAELSNHTRPVILVPGCMGNRLEAKLDKPNVVNWLCYRKTEDFFTIWLDFNMFLPLGVDCWIDNTRVVYNRSSGHMSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLAPRQQDEYYQKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLHFLLRQPQSWKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPIMSNIKLREEQRITTTSPWMFPAHHVWPEDHVFISTPNFNYTGQDFERFFADLHFEEGWHMFLQ... | aflatoxin metabolic process cholesterol homeostasis cholesterol metabolic process cholesterol transport high-density lipoprotein particle remodeling lipid metabolic process lipoprotein biosynthetic process lipoprotein metabolic process phosphatidylcholine biosynthetic process phosphatidylcholine metabolic process phosp... |
cellular response to heat cellular response to lipopolysaccharide connective tissue replacement involved in inflammatory response wound healing cytokine-mediated signaling pathway ectopic germ cell programmed cell death extrinsic apoptotic signaling pathway in absence of ligand fever generation immune response inflamma... | cytosol; extracellular space; nucleus | copper ion binding cytokine activity interleukin-1 receptor binding | Sus scrofa | Acetylation Cytokine Cytoplasm Glycoprotein Inflammatory response Mitogen Nucleus Phosphoprotein Pyrogen Reference proteome Secreted | MAKVPDLFED | MAKVPDLFEDLKNCYSENEEYSSDIDHLSLNQKSFYDASYEPLPGDGMDKFMPLSTSKTSKTSRLNFKDSVVMAAANGKILKKRRLSLNQFITDDDLEAIANDTEEEIIKPRSATYSFQSNMKYNFMRVINHQCILNDARNQSIIRDPSGQYLMAAVLNNLDEAVKFDMAAYTSNDDSQLPVTLRISETRLFVSAQNEDEPVLLKELPETPKTIKDETSLLFFWEKHGNMDYFKSAAHPKLFIATRQEKLVHMAPGLPSVTDFQILENQS | cellular response to heat cellular response to lipopolysaccharide connective tissue replacement involved in inflammatory response wound healing cytokine-mediated signaling pathway ectopic germ cell programmed cell death extrinsic apoptotic signaling pathway in absence of ligand fever generation immune response inflamma... |
flight locomotion muscle system process myofibril assembly post-embryonic development | cytoplasm; myofibril; myosin II complex | calcium ion binding myosin heavy chain binding | Drosophila melanogaster | Acetylation Calcium Metal-binding Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Repeat | MADEKKKVKK | MADEKKKVKKKKTKEEGGTSETASEAASEAATPAPAATPAPAASATGSKRASGGSRGSRKSKRAGSSVFSVFSQKQIAEFKEAFQLMDADKDGIIGKNDLRAAFDSVGKIANDKELDAMLGEASGPINFTQLLTLFANRMATSGANDEDEVVIAAFKTFDNDGLIDGDKFREMLMNFGDKFTMKEVDDAYDQMVIDDKNQIDTAALIEMLTGKGEEEEEEAA | flight locomotion muscle system process myofibril assembly post-embryonic development cytoplasm; myofibril; myosin II complex calcium ion binding myosin heavy chain binding Drosophila melanogaster Acetylation Calcium Metal-binding Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Repeat MADEKKKVKK M... |
dephosphorylation insulin receptor signaling pathway integrin-mediated signaling pathway modulation of chemical synaptic transmission regulation of focal adhesion assembly | extracellular exosome; focal adhesion; membrane; plasma membrane; receptor complex; Schaffer collateral - CA1 synapse; synaptic membrane | protein tyrosine phosphatase activity transmembrane receptor protein tyrosine phosphatase activity | Homo sapiens | 3D-structure Alternative splicing Cell junction Cell membrane Glycoprotein Hydrolase Membrane Phosphoprotein Protein phosphatase Reference proteome Repeat Signal Transmembrane Transmembrane helix | MDSWFILVLL | MDSWFILVLLGSGLICVSANNATTVAPSVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITLGPTYLTTVNSSDSDNGTTRTASTNSIGITISPNGTWLPDNQFTDARTEPWEGNSSTAATTPETFPPSGNSDSKDRRDETPIIAVMVALSSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKLEEEINRRMADDNKLFREEFNALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEET... | dephosphorylation insulin receptor signaling pathway integrin-mediated signaling pathway modulation of chemical synaptic transmission regulation of focal adhesion assembly extracellular exosome; focal adhesion; membrane; plasma membrane; receptor complex; Schaffer collateral - CA1 synapse; synaptic membrane protein tyr... |
cell adhesion intracellular potassium ion homeostasis intracellular sodium ion homeostasis potassium ion import across plasma membrane potassium ion transmembrane transport proton transmembrane transport sodium ion export across plasma membrane | apical plasma membrane; potassium:proton exchanging ATPase complex; sodium:potassium-exchanging ATPase complex | ATPase activator activity | Sus scrofa | 3D-structure Cell adhesion Cell membrane Direct protein sequencing Disulfide bond Glycoprotein Hydrogen ion transport Ion transport Membrane Potassium Potassium transport Reference proteome Signal-anchor Transmembrane Transmembrane helix Transport | MAALQEKKSC | MAALQEKKSCSQRMEEFQRYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMSGIFALCIYVLMRTIDPYTPDYQDQLKSPGVTLRPDVYGEKGLDISYNVSDSTTWAGLAHTLHRFLAGYSPAAQEGSINCTSEKYFFQESFLAPNHTKFSCKFTADMLQNCSGRPDPTFGFAEGKPCFIIKMNRIVKFLPGNSTAPRVDCAFLDQPRDGPPLQVEYFPANGTYSLHYFPYYGKKAQPHYSNPLVAAKLLNVPRNRDVVIVCKILAEHVSFDNPHDPYEGKVEFKLKIQK | cell adhesion intracellular potassium ion homeostasis intracellular sodium ion homeostasis potassium ion import across plasma membrane potassium ion transmembrane transport proton transmembrane transport sodium ion export across plasma membrane apical plasma membrane; potassium:proton exchanging ATPase complex; sodium:... |
xenobiotic metabolic process | cytosol | arylamine N-acetyltransferase activity | Homo sapiens | 3D-structure Acetylation Acyltransferase Cytoplasm Reference proteome Transferase | MDIEAYLERI | MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI | xenobiotic metabolic process cytosol arylamine N-acetyltransferase activity Homo sapiens 3D-structure Acetylation Acyltransferase Cytoplasm Reference proteome Transferase MDIEAYLERI MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQPLELI... |
adult chitin-containing cuticle pigmentation adult locomotory behavior catecholamine metabolic process courtship behavior cuticle pigmentation developmental pigmentation dopamine biosynthetic process dopamine biosynthetic process from tyrosine dopamine metabolic process male courtship behavior regulation of adult chiti... | axon; cytoplasm; perikaryon; perinuclear region of cytoplasm | iron ion binding tyrosine 3-monooxygenase activity | Drosophila melanogaster | Alternative splicing Catecholamine biosynthesis Cell projection Cytoplasm Iron Metal-binding Monooxygenase Neurotransmitter biosynthesis Oxidoreductase Reference proteome | MMAVAAAQKN | MMAVAAAQKNREMFAIKKSYSIENGYPSRRRSLVDDARFETLVVKQTKQTVLEEARSKANDDSLEDCIVQAQEHIPSEQDVELQDEHANLENLPLEEYVPVEEDVEFESVEQEQSESQSQEPEGNQQPTKNDYGLTEDEILLANAASESSDAEAAMQSAALVVRLKEGISSLGRILKAIETFHGTVQHVESRQSRVEGVDHDVLIKLDMTRGNLLQLIRSLRQSGSFSSMNLMADNNLNVKAPWFPKHASELDNCNHLMTKYEPDLDMNHPGFADKVYRQRRKEIAEIAFAYKYGDPIPFIDYSDVEVKTWRSVFKTVQD... | adult chitin-containing cuticle pigmentation adult locomotory behavior catecholamine metabolic process courtship behavior cuticle pigmentation developmental pigmentation dopamine biosynthetic process dopamine biosynthetic process from tyrosine dopamine metabolic process male courtship behavior regulation of adult chiti... |
apoptotic process cell differentiation phosphorylation positive regulation of cell population proliferation positive regulation of MAPK cascade regulation of macromolecule metabolic process transmembrane receptor protein tyrosine kinase signaling pathway | plasma membrane; receptor complex | ATP binding fibroblast growth factor binding fibroblast growth factor receptor activity | Gallus gallus | Apoptosis ATP-binding Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MRAAWGSVWC | MRAAWGSVWCLCLAAAVGALPAARRRGAERSGGQAAEYLRSETAFLEELVFGSGDTIELSCNTQSSSVSVFWFKDGIGIAPSNRTHIGQKLLKIINVSYDDSGLYSCKPRHSNEVLGNFTVRVTDSPSSGDDEDDDDESEDTGVPFWTRPDKMEKKLLAVPAANTVRFRCPAGGNPTPTIYWLKNGKEFKGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKYGNIRHTYQLDVLERSPHRPILQAGLPANQTVVVGSNVEFHCKVYSDAQPHIQWLKHVEVNGSKYGPDGTPYVTVLKTAGVNTTDKELEILYL... | apoptotic process cell differentiation phosphorylation positive regulation of cell population proliferation positive regulation of MAPK cascade regulation of macromolecule metabolic process transmembrane receptor protein tyrosine kinase signaling pathway plasma membrane; receptor complex ATP binding fibroblast growth f... |
apoptotic process phosphorylation positive regulation of cell population proliferation transmembrane receptor protein tyrosine kinase signaling pathway | cytoplasmic vesicle; Golgi apparatus; plasma membrane; receptor complex | ATP binding fibroblast growth factor binding fibroblast growth factor receptor activity | Gallus gallus | Apoptosis ATP-binding Cell membrane Cytoplasmic vesicle Disulfide bond Glycoprotein Golgi apparatus Immunoglobulin domain Kinase Membrane Nucleotide-binding Phosphoprotein Receptor Reference proteome Repeat Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase Ubl conjugation | MVSWDSGCLI | MVSWDSGCLICLVVVTMAGLSLARPSFNLVVEDATLEPEEPPTKYQISQPDVHSALPGEPLELRCQLKDAVMISWTKDGVPLGPDNRTVIIGEYLQIKDASPRDSGLYACTAIRTLDSDTLYFIVNVTDALSSGDDEDDNDGSEDFVNDSNQMRAPYWTHTDKMEKRLHAVPAANTVKFRCPAMGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCIVENQYGSINHTYHLDVVERSPHRPILQAGLPANASAVVGGDVEFVCKVYSDAQPHIQWIKHVERNGSKYGPDGLPYLQVLKAAGVN... | apoptotic process phosphorylation positive regulation of cell population proliferation transmembrane receptor protein tyrosine kinase signaling pathway cytoplasmic vesicle; Golgi apparatus; plasma membrane; receptor complex ATP binding fibroblast growth factor binding fibroblast growth factor receptor activity Gallus g... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation | late endosome membrane; lysosomal membrane; MHC class II protein complex | MHC class II protein complex binding peptide antigen binding | Pan troglodytes | Adaptive immunity Disulfide bond Endosome Glycoprotein Immunity Lysosome Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix | MGSGWVPWVV | MGSGWVPWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVYPERTPLLHQHNLLHCSVTGFYPGDIKIRWFLNGQEERARVMSTGPIRNGDWTFQTVVMLEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWKKMLSGIAAFLLGLIFLLVGIVIQLRAQKGYVRTQMSGNEVSRAVLLPQSC | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation late endosome membrane; lysosomal membrane; MHC class II protein complex M... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation response to type II interferon | cell surface; external side of plasma membrane; immunological synapse; late endosome membrane; lysosomal membrane; MHC class II protein complex; plasma membrane | CD4 receptor binding MHC class II protein complex binding MHC class II receptor activity peptide antigen binding polysaccharide binding T cell receptor binding | Mus musculus | 3D-structure Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MVWLPRVPCV | MVWLPRVPCVAAVILLLTVLSPPVALVRDSRPWFLEYCKSECHFYNGTQRVRFLKRYFYNLEENLRFDSDVGEFRAVTELGRPDAENWNSQPEILDEKRAAVDTYCRHNYEIFDNFLVPRRVEPTVTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDWTFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKAQSTSAQNKMLSGVGGFVLGLLFLRAGLFIYFRNQKGQSGLQPTGLLS | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation response to type II interferon cell surface; external side of plasma membr... |
adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation | cell surface; external side of plasma membrane; immunological synapse; late endosome membrane; lysosomal membrane; MHC class II protein complex; plasma membrane | CD4 receptor binding MHC class II protein complex binding MHC class II receptor activity peptide antigen binding polysaccharide binding T cell receptor binding | Mus musculus | Adaptive immunity Disulfide bond Glycoprotein Immunity Membrane MHC II Reference proteome Signal Transmembrane Transmembrane helix Ubl conjugation | MVWLPRVPCV | MVWLPRVPCVAAVILLLTVLSPPVALVRNSRPRFLEYSTSECHFYNGTQRVRFLERYIYNREEYVRFDSDVGEYRAVTELGRPDAEYWNSQPEILEDARATVDTYCRHNYEIFDNFLVPRRVEPTVTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDWTFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKAQSTSAQNKMLSGVGGFVLGLLFLGAGLFIYFRNQKGQSGLQPTGLLS | adaptive immune response antigen processing and presentation of exogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex positive regulation of immune response positive regulation of T cell activation cell surface; external side of plasma membrane; immunological synapse; lat... |
chorion-containing eggshell pattern formation gastrulation metamorphosis negative phototaxis negative regulation of hippo signaling negative regulation of multicellular organism growth peptidyl-tyrosine autophosphorylation pole cell fate determination pole cell migration positive regulation of MAPK cascade positive reg... | plasma membrane; receptor complex | ATP binding metal ion binding transmembrane receptor protein tyrosine kinase activity | Drosophila melanogaster | Alternative splicing ATP-binding Developmental protein Glycoprotein Kinase Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Receptor Reference proteome Signal Transferase Transmembrane Transmembrane helix Tyrosine-protein kinase | MLIFYAKYAF | MLIFYAKYAFIFWFFVGSNQGEMLLMDKISHDKTLLNVTACTQNCLEKGQMDFRSCLKDCRINGTFPGALRKVQENYQMNMICRTESEIVFQIDWVQHSRGTEPAPNATYIIRVDAVKDDNKETALYLSDDNFLILPGLESNSTHNITALAMHGDGSYSLIAKDQTFATLIRGYQPSKMGAVNLLRFVPQPDDLHHIAAEIEWKPSAESNCYFDMVSYSTNSVNMDEPLEVQFRDRKKLYRHTVDNLEFDKQYHVGVRTVNIMNRLESDLQWLPIAVPSCLDWYPYNYTLCPPHKPENLTVTQKQYLPNILALNITWARP... | chorion-containing eggshell pattern formation gastrulation metamorphosis negative phototaxis negative regulation of hippo signaling negative regulation of multicellular organism growth peptidyl-tyrosine autophosphorylation pole cell fate determination pole cell migration positive regulation of MAPK cascade positive reg... |
carbon catabolite activation of transcription from RNA polymerase II promoter chromatin remodeling double-strand break repair via homologous recombination positive regulation of invasive growth in response to glucose limitation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA... | chromatin; cytosol; nuclear chromosome; nucleus; SWI/SNF complex | RNA polymerase II-specific DNA-binding transcription factor binding | Saccharomyces cerevisiae | 3D-structure Activator Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MNNQPQGTNS | MNNQPQGTNSVPNSIGNIFSNIGTPSFNMAQIPQQLYQSLTPQQLQMIQQRHQQLLRSRLQQQQQQQQQTSPPPQTHQSPPPPPQQSQPIANQSATSTPPPPPAPHNLHPQIGQVPLAPAPINLPPQIAQLPLATQQQVLNKLRQQAIAKNNPQVVNAITVAQQQVQRQIEQQKGQQTAQTQLEQQRQLLVQQQQQQQLRNQIQRQQQQQFRHHVQIQQQQQKQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGQIPQSQQVPQVRSMSGQPPTNVQPTIGQLPQLPKLNLPKYQTIQYDPPETK... | carbon catabolite activation of transcription from RNA polymerase II promoter chromatin remodeling double-strand break repair via homologous recombination positive regulation of invasive growth in response to glucose limitation positive regulation of transcription by RNA polymerase II regulation of transcription by RNA... |
clathrin-dependent endocytosis intracellular protein transport | AP-2 adaptor complex; cytoplasmic vesicle; membrane coat; plasma membrane; synaptic vesicle | clathrin adaptor activity disordered domain specific binding kinase binding phosphatidylinositol binding protein domain specific binding protein kinase binding protein serine/threonine kinase binding protein-containing complex binding | Rattus norvegicus | 3D-structure Cell membrane Coated pit Direct protein sequencing Endocytosis Lipid-binding Membrane Protein transport Reference proteome Transport | MPAVSKGEGM | MPAVSKGEGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHD... | clathrin-dependent endocytosis intracellular protein transport AP-2 adaptor complex; cytoplasmic vesicle; membrane coat; plasma membrane; synaptic vesicle clathrin adaptor activity disordered domain specific binding kinase binding phosphatidylinositol binding protein domain specific binding protein kinase binding prote... |
amino acid metabolic process catecholamine metabolic process chitin-based cuticle development cuticle development | cytoplasm | 3,4-dihydroxyphenylacetaldehyde synthase activity aromatic-L-amino-acid decarboxylase activity carboxy-lyase activity pyridoxal phosphate binding structural constituent of cuticle | Drosophila melanogaster | 3D-structure Alternative splicing Catecholamine metabolism Cuticle Lyase Pyridoxal phosphate Reference proteome | MDAKEFREFG | MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIKPGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPAHFQHASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSCIEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSAVCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDAN... | amino acid metabolic process catecholamine metabolic process chitin-based cuticle development cuticle development cytoplasm 3,4-dihydroxyphenylacetaldehyde synthase activity aromatic-L-amino-acid decarboxylase activity carboxy-lyase activity pyridoxal phosphate binding structural constituent of cuticle Drosophila melan... |
anterior head segmentation axonogenesis brain development brain segmentation cell differentiation dendrite morphogenesis embryonic development via the syncytial blastoderm neuroblast development open tracheal system development pattern specification process regulation of gene expression regulation of transcription by R... | nucleus | DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding | Drosophila melanogaster | Developmental protein DNA-binding Homeobox Nucleus Reference proteome | MTKMIPPVPT | MTKMIPPVPTAAAAVMMPTPKQKIGFSIESIVGNDVSTAGGNSTPDLSGPQSPPPGERNVPGSPPQTPPATLTLIPGSPPHHLMAPPAHGLPYPHPHAQQQQQQHLQAPHPHPHLSPAQQHVLHQHLLMQHQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSLKRERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQ... | anterior head segmentation axonogenesis brain development brain segmentation cell differentiation dendrite morphogenesis embryonic development via the syncytial blastoderm neuroblast development open tracheal system development pattern specification process regulation of gene expression regulation of transcription by R... |
neurotransmitter secretion positive regulation of vesicle fusion synaptic vesicle docking vesicle fusion vesicle-mediated transport | plasma membrane; SNARE complex; synaptic vesicle; synaptic vesicle membrane | SNAP receptor activity SNARE binding syntaxin binding | Drosophila melanogaster | Alternative splicing Cell membrane Coiled coil Cytoplasmic vesicle Membrane Reference proteome Synapse Transmembrane Transmembrane helix Ubl conjugation | MENNEAPSPS | MENNEAPSPSGSNNNDFPILPPPPNANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERADQLEQGASQFEQQAGKLKRKQWWANMKMMIILGVIAVVLLIIVLVSVWPSSSDSGSGGGNKAITQAPPH | neurotransmitter secretion positive regulation of vesicle fusion synaptic vesicle docking vesicle fusion vesicle-mediated transport plasma membrane; SNARE complex; synaptic vesicle; synaptic vesicle membrane SNAP receptor activity SNARE binding syntaxin binding Drosophila melanogaster Alternative splicing Cell membrane... |
cell differentiation chaeta morphogenesis chorion-containing eggshell pattern formation circadian regulation of gene expression compound eye cone cell differentiation determination of left/right symmetry dorsal appendage formation dorsal closure head involution hindgut development imaginal disc-derived wing morphogenes... | cytoplasm; nucleoplasm; nucleus | protein heterodimerization activity transcription corepressor activity | Drosophila melanogaster | Nucleus Phosphoprotein Reference proteome Repressor Transcription Transcription regulation | MKSLTAVCQT | MKSLTAVCQTGASGMPALNASGRIQRHPTHRGDGENAEMKMYLSKLKDLVPFMPKNRKLTKLEIIQHVIDYICDLQTELETHPEMGNFDAAAALTAVNGLHEDEDSDMEDADAEAEAEVDPDILAQRLNAEQPAKVSSPAARLPLTDRQTPNTLVAPAHPQQHQQQQQLQLQQQQLQSQQQLSNSLATPQNAEKDSRQS | cell differentiation chaeta morphogenesis chorion-containing eggshell pattern formation circadian regulation of gene expression compound eye cone cell differentiation determination of left/right symmetry dorsal appendage formation dorsal closure head involution hindgut development imaginal disc-derived wing morphogenes... |
apoptotic process ATP generation from poly-ADP-D-ribose decidualization DNA ADP-ribosylation DNA damage response double-strand break repair innate immune response negative regulation of innate immune response negative regulation of transcription by RNA polymerase II positive regulation of cardiac muscle hypertrophy pos... | chromatin; cytosol; nuclear envelope; nuclear replication fork; nucleolus; nucleus; site of DNA damage; site of double-strand break | damaged DNA binding NAD binding NAD+ ADP-ribosyltransferase activity NAD+- protein-aspartate ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-histidine ADP-ribosyltransferase activity NAD+-protein-serine ADP-ribosyltransfera... | Bos taurus | Acetylation ADP-ribosylation Allosteric enzyme Apoptosis Chromosome Cytoplasm DNA damage DNA repair DNA-binding Glycosyltransferase Immunity Innate immunity Isopeptide bond Metal-binding NAD Nucleotidyltransferase Nucleus Phosphoprotein Reference proteome Repeat Transcription Transcription regulation Transferase Ubl co... | MAESSDKLYR | MAESSDKLYRVEYAKSGRASCKKCKESIPKDSIRMAFMVESPMFDGKIPHWYHLSCFWKVGFSIWHPDVEVEGFSELRWDDQQTIKKMAETGGRTDVSGKGQDGVGSKTEKTLIDFGAGYAKSNRSTCKSCMEKIDKGQVRLSKKVVYPDKPQLGMVDCWYHPKCFVQKREELGFRPEFSATHLMGFSVLTAEDQETLKKQLPAIKGERKRKGDEVDGIDEVTKKKSKKEKDKEIKLEKALKAQNDLIWNVKDELKKACSTNDLKELLIFNKQEVPSGESAILDRVADGMVFGALLPCEECSGQLVFKGDAYYCTGDVTA... | apoptotic process ATP generation from poly-ADP-D-ribose decidualization DNA ADP-ribosylation DNA damage response double-strand break repair innate immune response negative regulation of innate immune response negative regulation of transcription by RNA polymerase II positive regulation of cardiac muscle hypertrophy pos... |
negative regulation of transcription by RNA polymerase II nitrate assimilation nitrogen catabolite activation of transcription from RNA polymerase II promoter positive regulation of transcription by RNA polymerase II | cytosol; nucleus | DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding zinc ion binding | Saccharomyces cerevisiae | Activator DNA-binding Metal-binding Nitrate assimilation Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation Zinc Zinc-finger | MQDDPENSKL | MQDDPENSKLYDLLNSHLDVHGRSNEEPRQTGDSRSQSSGNTGENEEDIAFASGLNGGTFDSMLEALPDDLYFTDFVSPFTAAATTSVTTKTVKDTTPATNHMDDDIAMFDSLATTQPIDIAASNQQNGEIAQLWDFNVDQFNMTPSNSSGSATISAPNSFTSDIPQYNHGSLGNSVSKSSLFPYNSSTSNSNINQPSINNNSNTNAQSHHSFNIYKLQNNNSSSSAMNITNNNNSNNSNIQHPFLKKSDSIGLSSSNTTNSVRKNSLIKPMSSTSLANFKRAASVSSSISNMEPSGQNKKPLIQCFNCKTFKTPLWRRS... | negative regulation of transcription by RNA polymerase II nitrate assimilation nitrogen catabolite activation of transcription from RNA polymerase II promoter positive regulation of transcription by RNA polymerase II cytosol; nucleus DNA-binding transcription factor activity DNA-binding transcription factor activity, R... |
cellular response to histamine central nervous system neuron development chloride transmembrane transport gamma-aminobutyric acid signaling pathway monoatomic ion transport ovulation cycle response to progesterone response to toxic substance signal transduction | chloride channel complex; dendrite; GABA-A receptor complex; GABA-ergic synapse; neuron projection; nuclear envelope; plasma membrane; postsynaptic specialization membrane; presynaptic active zone membrane; Schaffer collateral - CA1 synapse; synapse | G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential GABA receptor binding GABA-A receptor activity GABA-gated chloride ion channel activity ligand-gated monoatomic ion channel activity ligand-gated monoatomic ion channel activity involved in regulation of presyn... | Homo sapiens | Alternative splicing Cell membrane Chloride Chloride channel Disease variant Disulfide bond Epilepsy Glycoprotein Ion channel Ion transport Ligand-gated ion channel Membrane Postsynaptic cell membrane Receptor Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MWTVQNRESL | MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLA... | cellular response to histamine central nervous system neuron development chloride transmembrane transport gamma-aminobutyric acid signaling pathway monoatomic ion transport ovulation cycle response to progesterone response to toxic substance signal transduction chloride channel complex; dendrite; GABA-A receptor comple... |
chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway synaptic transmission, GABAergic | axon; chloride channel complex; dendrite; GABA-A receptor complex; GABA-ergic synapse; glutamatergic synapse; neuron projection; neuronal cell body; postsynaptic membrane; synapse | chloride channel activity GABA-A receptor activity neurotransmitter receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | Cell membrane Chloride Chloride channel Disulfide bond Glycoprotein Ion channel Ion transport Membrane Phosphoprotein Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MDVLGWLLLP | MDVLGWLLLPLLLLCTQPHHGARAMNDIGDYVGSNLEISWLPNLDGLMEGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYNHTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSENQEQIHGLDRLQLAQFTITSYRFTTELMNFKSAGQFPRLSLHFQLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVF... | chemical synaptic transmission chloride transmembrane transport gamma-aminobutyric acid signaling pathway synaptic transmission, GABAergic axon; chloride channel complex; dendrite; GABA-A receptor complex; GABA-ergic synapse; glutamatergic synapse; neuron projection; neuronal cell body; postsynaptic membrane; synapse c... |
adult behavior cellular response to histamine chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly post-embryonic development regulation of postsynaptic membrane potential synaptic transmission, GABAergic | axon; chloride channel complex; cytoplasmic vesicle membrane; dendrite membrane; GABA-A receptor complex; GABA-ergic synapse; neuron projection; plasma membrane; postsynapse; postsynaptic membrane; synapse | benzodiazepine receptor activity chloride channel activity GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity neurotransmitter receptor activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic m... | Homo sapiens | 3D-structure Alternative splicing Cell membrane Cell projection Chloride Chloride channel Cytoplasmic vesicle Disease variant Disulfide bond Epilepsy Glycoprotein Ion channel Ion transport Lipoprotein Membrane Palmitate Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Trans... | MSSPNIWSTG | MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLST... | adult behavior cellular response to histamine chloride transmembrane transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly post-embryonic development regulation of postsynaptic membrane potential synaptic transmission, GABAergic axon; chloride channel complex; cytoplasmic vesicle membrane; den... |
adult behavior cellular response to histamine chemical synaptic transmission chloride transmembrane transport chloride transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly post-embryonic development regulation of postsynaptic membrane potential synaptic transmission, GABAergic | axon; chloride channel complex; cytoplasmic vesicle membrane; dendrite membrane; GABA receptor complex; GABA-A receptor complex; GABA-ergic synapse; glutamatergic synapse; inhibitory synapse; neuron projection; plasma membrane; postsynapse; postsynaptic specialization membrane; synapse | chloride channel activity GABA-A receptor activity GABA-gated chloride ion channel activity inhibitory extracellular ligand-gated monoatomic ion channel activity transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | Rattus norvegicus | 3D-structure Cell membrane Cell projection Chloride Chloride channel Cytoplasmic vesicle Disulfide bond Glycoprotein Ion channel Ion transport Lipoprotein Membrane Palmitate Postsynaptic cell membrane Reference proteome Signal Synapse Transmembrane Transmembrane helix Transport | MSSPNTWSTG | MSSPNTWSTGSTVYSPVFSQKMTLWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI... | adult behavior cellular response to histamine chemical synaptic transmission chloride transmembrane transport chloride transport gamma-aminobutyric acid signaling pathway inhibitory synapse assembly post-embryonic development regulation of postsynaptic membrane potential synaptic transmission, GABAergic axon; chloride ... |
activation of adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway cAMP-mediated signaling cell-cell signaling female pregnancy insulin secretion negative regulation of cell cycle neuron projection development neuropeptide signaling pathway positive regulation of chemokin... | extracellular region; neuron projection; perikaryon | neuropeptide hormone activity peptide hormone receptor binding pituitary adenylate cyclase activating polypeptide activity signaling receptor binding | Homo sapiens | 3D-structure Amidation Cleavage on pair of basic residues Hormone Neurogenesis Reference proteome Secreted Signal | MTMCSGARLA | MTMCSGARLALLVYGIIMHSSVYSSPAAAGLRFPGIRPEEEAYGEDGNPLPDFDGSEPPGAGSPASAPRAAAAWYRPAGRRDVAHGILNEAYRKVLDQLSAGKHLQSLVARGVGGSLGGGAGDDAEPLSKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNKGRRIAYL | activation of adenylate cyclase activity adenylate cyclase-activating G protein-coupled receptor signaling pathway cAMP-mediated signaling cell-cell signaling female pregnancy insulin secretion negative regulation of cell cycle neuron projection development neuropeptide signaling pathway positive regulation of chemokin... |
acute-phase response immune response inflammatory response to antigenic stimulus insulin secretion lipid metabolic process negative regulation of heterotypic cell-cell adhesion negative regulation of interleukin-1-mediated signaling pathway response to glucocorticoid | centrosome; cytosol; extracellular exosome; extracellular space; nucleoplasm; plasma membrane | cytokine activity interleukin-1 receptor antagonist activity interleukin-1 receptor binding interleukin-1 type I receptor antagonist activity interleukin-1 type II receptor antagonist activity interleukin-1, type I receptor binding interleukin-1, type II receptor binding | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Disulfide bond Glycoprotein Pharmaceutical Reference proteome Secreted Signal | MEICRGLRSH | MEICRGLRSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE | acute-phase response immune response inflammatory response to antigenic stimulus insulin secretion lipid metabolic process negative regulation of heterotypic cell-cell adhesion negative regulation of interleukin-1-mediated signaling pathway response to glucocorticoid centrosome; cytosol; extracellular exosome; extracel... |
apoptotic process cell differentiation circadian regulation of gene expression nervous system development Rho protein signal transduction | cell surface; dendritic spine; growth cone; perikaryon; plasma membrane | coreceptor activity death receptor activity nerve growth factor binding neurotrophin binding | Gallus gallus | Apoptosis Biological rhythms Cell membrane Cell projection Developmental protein Differentiation Disulfide bond Glycoprotein Membrane Neurogenesis Phosphoprotein Receptor Reference proteome Repeat Signal Synapse Transmembrane Transmembrane helix | MAGFVPLLLL | MAGFVPLLLLLLPAGPTWGSKEKCLTKMYTTSGECCKACNLGEGVVQPCGVNQTVCEPCLDSVTYSDTVSATEPCKPCTQCVGLHSMSAPCVESDDAVCRCAYGYFQDELSGSCKECSICEVGFGLMFPCRDSQDTVCEECPEGTFSDEANFVDPCLPCTICEENEVMVKECTATSDAECRDLHPRWTTHTPSLAGSDSPEPITRDPFNTEGMATTLADIVTTVMGSSQPVVSRGTADNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANNRPVNQTPSPEGEKLHSDSGISVDSQSLHDQQPPNQSTQGPAPKG... | apoptotic process cell differentiation circadian regulation of gene expression nervous system development Rho protein signal transduction cell surface; dendritic spine; growth cone; perikaryon; plasma membrane coreceptor activity death receptor activity nerve growth factor binding neurotrophin binding Gallus gallus Apo... |
viral budding from plasma membrane viral budding via host ESCRT complex | host cell perinuclear region of cytoplasm; host cell plasma membrane; membrane; virion component | RNA binding zinc ion binding | Lymphocytic choriomeningitis virus | 3D-structure Host cell membrane Host cytoplasm Host membrane Host-virus interaction Lipoprotein Membrane Metal-binding Myristate Reference proteome Viral budding Viral budding via the host ESCRT complexes Viral release from host cell Virion Zinc Zinc-finger | MGQGKSREEK | MGQGKSREEKGTNSTNRAEILPDTTYLGPLSCKSCWQKFDSLVRCHDHYLCRHCLNLLLSVSDRCPLCKYPLPTRLKISTAPSSPPPYEE | viral budding from plasma membrane viral budding via host ESCRT complex host cell perinuclear region of cytoplasm; host cell plasma membrane; membrane; virion component RNA binding zinc ion binding Lymphocytic choriomeningitis virus 3D-structure Host cell membrane Host cytoplasm Host membrane Host-virus interaction Li... |
positive regulation of epidermal growth factor receptor signaling pathway positive regulation of G protein-coupled receptor signaling pathway positive regulation of MAPK cascade response to stimulus visual perception | photoreceptor disc membrane; photoreceptor outer segment membrane; plasma membrane | 3',5'-cyclic-GMP phosphodiesterase activity cGMP binding enzyme inhibitor activity spectrin binding | Homo sapiens | 3D-structure Acetylation cGMP Hydrolase Reference proteome Retinitis pigmentosa Sensory transduction Vision | MNLEPPKAEF | MNLEPPKAEFRSATRVAGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII | positive regulation of epidermal growth factor receptor signaling pathway positive regulation of G protein-coupled receptor signaling pathway positive regulation of MAPK cascade response to stimulus visual perception photoreceptor disc membrane; photoreceptor outer segment membrane; plasma membrane 3',5'-cyclic-GMP pho... |
pyrimidine-containing compound salvage UMP salvage | cytoplasm | GTP binding uracil phosphoribosyltransferase activity | Saccharomyces cerevisiae | Allosteric enzyme Glycosyltransferase GTP-binding Nucleotide-binding Phosphoprotein Reference proteome Transferase | MSSEPFKNVY | MSSEPFKNVYLLPQTNQLLGLYTIIRNKNTTRPDFIFYSDRIIRLLVEEGLNHLPVQKQIVETDTNENFEGVSFMGKICGVSIVRAGESMEQGLRDCCRSVRIGKILIQRDEETALPKLFYEKLPEDISERYVFLLDPMLATGGSAIMATEVLIKRGVKPERIYFLNLICSKEGIEKYHAAFPEVRIVTGALDRGLDENKYLVPGLGDFGDRYYCV | pyrimidine-containing compound salvage UMP salvage cytoplasm GTP binding uracil phosphoribosyltransferase activity Saccharomyces cerevisiae Allosteric enzyme Glycosyltransferase GTP-binding Nucleotide-binding Phosphoprotein Reference proteome Transferase MSSEPFKNVY MSSEPFKNVYLLPQTNQLLGLYTIIRNKNTTRPDFIFYSDRIIRLLVEEGLNH... |
bone development bronchiole development cell adhesion cell adhesion mediated by integrin cell morphogenesis cell-matrix adhesion cellular response to ionizing radiation enamel mineralization hard palate development immune response inflammatory response integrin-mediated signaling pathway Langerhans cell differentiation... | cell junction; cell surface; centrosome; external side of plasma membrane; focal adhesion; integrin alphav-beta6 complex; integrin complex; nucleoplasm; plasma membrane; receptor complex | integrin binding metal ion binding molecular function activator activity virus receptor activity | Homo sapiens | 3D-structure Alternative splicing Amelogenesis imperfecta Calcium Cell adhesion Cell junction Cell membrane Disease variant Disulfide bond EGF-like domain Glycoprotein Host cell receptor for virus entry Host-virus interaction Integrin Magnesium Membrane Metal-binding Receptor Reference proteome Repeat Signal Transmembr... | MGIELLCLFF | MGIELLCLFFLFLGRNDHVQGGCALGGAETCEDCLLIGPQCAWCAQENFTHPSGVGERCDTPANLLAKGCQLNFIENPVSQVEILKNKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLV... | bone development bronchiole development cell adhesion cell adhesion mediated by integrin cell morphogenesis cell-matrix adhesion cellular response to ionizing radiation enamel mineralization hard palate development immune response inflammatory response integrin-mediated signaling pathway Langerhans cell differentiation... |
angiogenesis cell differentiation decidualization embryo implantation endothelial tube morphogenesis neural retina development neutrophil chemotaxis odontogenesis of dentin-containing tooth photoreceptor cell maintenance positive regulation of endothelial cell migration positive regulation of interleukin-6 production p... | acrosomal membrane; basolateral plasma membrane; endoplasmic reticulum membrane; endosome; intracellular membrane-bounded organelle; photoreceptor inner segment; photoreceptor outer segment; plasma membrane; sarcolemma | mannose binding signaling receptor activity virus receptor activity | Mus musculus | 3D-structure Alternative splicing Angiogenesis Cell membrane Cell projection Differentiation Direct protein sequencing Disulfide bond Endoplasmic reticulum Glycoprotein Immunoglobulin domain Lectin Mannose-binding Membrane Phosphoprotein Receptor Reference proteome Signal Spermatogenesis Transmembrane Transmembrane hel... | MAAALLLALA | MAAALLLALAFTLLSGQGACAAAGFLKAPLSQERWAGGSVVLHCEAVGSPIPEIQWWFEGNAPNDSCSQLWDGARLDRVHIHAAYRQHAASSLSVDGLTAEDTGTYECRASSDPDRNHLTRPPRVKWVRAQASVVVLEPGTIQTSVQEVNSKTQLTCSLNSSGVDIVGHRWMRGGKVLQEDTLPDLHTKYIVDADDRSGEYSCIFLPEPVGRSEINVEGPPRIKVGKKSEHSSEGELAKLVCKSDASYPPITDWFWFKTSDTGEEEAITNSTEANGKYVVVSTPEKSQLTISNLDVNVDPGTYVCNATNAQGTTRETISL... | angiogenesis cell differentiation decidualization embryo implantation endothelial tube morphogenesis neural retina development neutrophil chemotaxis odontogenesis of dentin-containing tooth photoreceptor cell maintenance positive regulation of endothelial cell migration positive regulation of interleukin-6 production p... |
positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of histone acetylation regulation of transcription by RNA polymerase II rhythmic process transcription by RNA polymerase II | CCAAT-binding factor complex; nucleoplasm; nucleus; protein-DNA complex; RNA polymerase II transcription regulator complex | DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding sequence-specific DNA binding transcription coregulat... | Rattus norvegicus | Activator Biological rhythms Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome Transcription Transcription regulation | MEQYTANSNS | MEQYTANSNSSTEQIVVQAGQIQQQQQGGVTAVQLQTEAQVASASGQQVQTLQVVQGQPLMVQVSGGQLITSTGQPIMVQAVPGGQGQTIMQVPVSGTQGLQQIQLVPPGQIQIQGGQAVQVQGQQGQTQQIIIQQPQTAVTAGQTQTQQQIAVQGQQVAQTAEGQTIVYQPVNADGTILQQGMITIPAASLAGAQIVQTGANTNTTSSGQGTVTVTLPVAGNVVNSGGMVMMVPGAGSVPAIQRIPLPGAEMLEEEPLYVNAKQYHRILKRRQARAKLEAEGKIPKERRKYLHESRHRHAMARKRGEGGRFFSPKEKDS... | positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of histone acetylation regulation of transcription by RNA polymerase II rhythmic process transcription by RNA polymerase II CCAAT-binding factor complex; nucl... |
ammonium homeostasis ammonium transmembrane transport | ankyrin-1 complex; plasma membrane | ammonium transmembrane transporter activity | Homo sapiens | 3D-structure Alternative splicing Blood group antigen Direct protein sequencing Membrane Reference proteome Transmembrane Transmembrane helix | MSSKYPRSVR | MSSKYPRSVRRCLPLCALTLEAALILLFYFFTHYDASLEDQKGLVASYQVGQDLTVMAALGLGFLTSNFRRHSWSSVAFNLFMLALGVQWAILLDGFLSQFPPGKVVITLFSIRLATMSAMSVLISAGAVLGKVNLAQLVVMVLVEVTALGTLRMVISNIFNTDYHMNLRHFYVFAAYFGLTVAWCLPKPLPKGTEDNDQRATIPSLSAMLGALFLWMFWPSVNSALLRSPIQRKNAMFNTYYALAVSVVTAISGSSLAHPQRKISMTYVHSAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLISIGGAKCLPVCCNRVL... | ammonium homeostasis ammonium transmembrane transport ankyrin-1 complex; plasma membrane ammonium transmembrane transporter activity Homo sapiens 3D-structure Alternative splicing Blood group antigen Direct protein sequencing Membrane Reference proteome Transmembrane Transmembrane helix MSSKYPRSVR MSSKYPRSVRRCLPLCALTLE... |
amino acid import across plasma membrane establishment of localization in cell L-alpha-amino acid transmembrane transport L-amino acid transport L-arginine import across plasma membrane L-arginine transmembrane transport L-ornithine transmembrane transport macrophage activation nitric oxide biosynthetic process nitric ... | cell junction; membrane; plasma membrane | amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-arginine transmembrane transporter activity L-lysine transmembrane transporter activity L-ornithine transmembrane transporter activity | Mus musculus | Alternative splicing Amino-acid transport Cell membrane Glycoprotein Membrane Phosphoprotein Reference proteome Transmembrane Transmembrane helix Transport | MIPCRAVLTF | MIPCRAVLTFARCLIRRKIVTLDSLEDSKLCRCLTTVDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLNKQIGQFFKTYFKMNYTGLAEYPDFFAVCLVLLLAGLLSFGVKESAWVNKFFTAINILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYLLD... | amino acid import across plasma membrane establishment of localization in cell L-alpha-amino acid transmembrane transport L-amino acid transport L-arginine import across plasma membrane L-arginine transmembrane transport L-ornithine transmembrane transport macrophage activation nitric oxide biosynthetic process nitric ... |
defense response to virus innate immune response interleukin-27-mediated signaling pathway negative regulation of viral genome replication response to virus | cytoplasm; endoplasmic reticulum membrane; membrane; microtubule; nucleus; perinuclear region of cytoplasm | GTP binding GTPase activity identical protein binding microtubule binding | Rattus norvegicus | Antiviral defense Cytoplasm Direct protein sequencing Endoplasmic reticulum GTP-binding Immunity Innate immunity Membrane Nucleotide-binding Nucleus Reference proteome Ubl conjugation | MKERTSACRH | MKERTSACRHGTPQKHPDTSEESQAMESVDNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKQLKQGEKWSGKVIYKDTEIEISHPSLVEREINKAQNLIAGEGLKISSDLISLEVSSPHVPDLTLIDLPGITRVAVGDQPADIEHKIKRLITEYIQKQETINLVVVPSNVDIATTEALKMAQEVDPQGDRTIGILTKPDLVDRGTEDKVVDVVRNLVCHLKKGYMIVKCRGQQDIQEQLSLAEALQKEQVFFKEHPQFRVLLEDGKATVPCLAKRLTM... | defense response to virus innate immune response interleukin-27-mediated signaling pathway negative regulation of viral genome replication response to virus cytoplasm; endoplasmic reticulum membrane; membrane; microtubule; nucleus; perinuclear region of cytoplasm GTP binding GTPase activity identical protein binding mi... |
calcium ion transmembrane transport calcium ion transport from cytosol to endoplasmic reticulum endoplasmic reticulum calcium ion homeostasis intracellular calcium ion homeostasis intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress liver regeneration | endoplasmic reticulum; organelle membrane; sarcoplasmic reticulum; sarcoplasmic reticulum membrane | ATP binding ATP hydrolysis activity calcium ion binding calcium ion transmembrane transporter activity calcium-dependent ATPase activity cysteine-type endopeptidase activator activity involved in apoptotic process P-type calcium transporter activity transmembrane transporter binding | Rattus norvegicus | Acetylation Alternative splicing ATP-binding Calcium Calcium transport Endoplasmic reticulum Ion transport Magnesium Membrane Metal-binding Nucleotide-binding Phosphoprotein Reference proteome Sarcoplasmic reticulum Translocase Transmembrane Transmembrane helix Transport | MEEAHLLSAA | MEEAHLLSAADVLRRFSVTAEGGLTLEQVTDARERYGPNELPTEEGKSLWELVVEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTDAIPDPRAVNQDKKNMLFSGTNIASGKALGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAIPEGLPAVITTCLA... | calcium ion transmembrane transport calcium ion transport from cytosol to endoplasmic reticulum endoplasmic reticulum calcium ion homeostasis intracellular calcium ion homeostasis intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress liver regeneration endoplasmic reticulum; organelle membra... |
cell adhesion pH reduction regulation of proton transport sodium ion transport | apical plasma membrane; endoplasmic reticulum; plasma membrane; sodium:potassium-exchanging ATPase complex | P-type potassium:proton transporter activity | Oryctolagus cuniculus | Cell adhesion Cell membrane Disulfide bond Glycoprotein Hydrogen ion transport Ion transport Membrane Potassium Potassium transport Reference proteome Signal-anchor Transmembrane Transmembrane helix Transport | MAALQEKKSC | MAALQEKKSCSQRMEEFRHYCWNPDTGQMLGRTLSRWVWISLYYVAFYVVMTGLFALCIYVLMQTIDPYTPDYQDQLKSPGVTLRPDVYGEKGLEIHYNISDNRTWTSLTHTLRSFLAGYSPAAQVDNINCTSKTYFFQESFGAPNHTKFSCKFTADMLENCSGLTDPSFGFKEGKPCFIIKMNRIVRFLPSNSTPPRVDCTFLDMPHQALTPLQVEYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNVPTNTEVVVLCKILADHVTFDNPHDPYEGKVEFKLKIQK | cell adhesion pH reduction regulation of proton transport sodium ion transport apical plasma membrane; endoplasmic reticulum; plasma membrane; sodium:potassium-exchanging ATPase complex P-type potassium:proton transporter activity Oryctolagus cuniculus Cell adhesion Cell membrane Disulfide bond Glycoprotein Hydrogen io... |
cell adhesion intracellular potassium ion homeostasis intracellular sodium ion homeostasis pH reduction potassium ion import across plasma membrane potassium ion transmembrane transport proton transmembrane transport response to lipopolysaccharide response to organonitrogen compound sodium ion export across plasma memb... | apical plasma membrane; potassium:proton exchanging ATPase complex; sodium:potassium-exchanging ATPase complex | ATPase activator activity | Rattus norvegicus | Cell adhesion Cell membrane Disulfide bond Glycoprotein Hydrogen ion transport Ion transport Membrane Potassium Potassium transport Reference proteome Signal-anchor Transmembrane Transmembrane helix Transport | MAALQEKKSC | MAALQEKKSCSQRMAEFRQYCWNPDTGQMLGRTPARWVWISLYYAAFYVVMTGLFALCIYVLMQTIDPYTPDYQDQLKSPGVTLRPDVYGERGLQISYNISENSSWAGLTHTLHSFLAGYTPASQQDSINCSSEKYFFQETFSAPNHTKFSCKFTADMLQNCSGLVDPSFGFEEGKPCFIIKMNRIVKFLPSNNTAPRVDCTFQDDPQKPRKDIEPLQVQYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKFLNVPKNTQVLIVCKIMADHVTFDNPHDPYEGKVEFKLTIQK | cell adhesion intracellular potassium ion homeostasis intracellular sodium ion homeostasis pH reduction potassium ion import across plasma membrane potassium ion transmembrane transport proton transmembrane transport response to lipopolysaccharide response to organonitrogen compound sodium ion export across plasma memb... |
behavior glycolytic process intracellular calcium ion homeostasis phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of ERK1 and ERK2 cascade positive regulation of fat cell differentiation positive regulation of glycolytic process positive regulation of peptidyl-tyrosine phosphoryla... | axon; caveola; cytoplasmic vesicle; dendrite; G protein-coupled serotonin receptor complex; presynapse | 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding Gq/11-coupled serotonin receptor activity identical protein binding protein tyrosine kinase activator activity serotonin binding | Cricetulus griseus | Behavior Cell membrane Cell projection Cytoplasmic vesicle Disulfide bond G-protein coupled receptor Glycoprotein Membrane Phosphoprotein Receptor Synapse Transducer Transmembrane Transmembrane helix | MEILCEDNTS | MEILCEDNTSLSSIPNSLMQVDGDSGLYRNDFNSRDANSSDASNWTIDGENRTNLSFEGYLPPTCLSILHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGVSMPIPVFGLQDDSKVFKQGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQK... | behavior glycolytic process intracellular calcium ion homeostasis phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of ERK1 and ERK2 cascade positive regulation of fat cell differentiation positive regulation of glycolytic process positive regulation of peptidyl-tyrosine phosphoryla... |
chromatin organization post-embryonic camera-type eye morphogenesis pyrimidine dimer repair by nucleotide-excision repair regulation of development, heterochronic regulation of epithelial cell proliferation regulation of transcription by RNA polymerase II response to UV-B response to UV-C transcription-coupled nucleoti... | chromatin; cytoplasm; female germ cell nucleus; nucleoplasm; nucleus | chromatin binding nucleosomal DNA binding | Mus musculus | Acetylation ADP-ribosylation Cytoplasm Direct protein sequencing DNA-binding Nucleus Phosphoprotein Reference proteome | MPKRKVSADG | MPKRKVSADGAAKAEPKRRSARLSAKPAPAKVDAKPKKAAGKDKASDKKVQIKGKRGAKGKQADVADQQTTELPAENGETENQSPASEEEKEAKSD | chromatin organization post-embryonic camera-type eye morphogenesis pyrimidine dimer repair by nucleotide-excision repair regulation of development, heterochronic regulation of epithelial cell proliferation regulation of transcription by RNA polymerase II response to UV-B response to UV-C transcription-coupled nucleoti... |
actomyosin structure organization cellular response to cGMP chemotaxis hyperosmotic response microtubule cytoskeleton organization involved in mitosis mitotic cytokinesis negative regulation of cell migration negative regulation of pinocytosis nucleus organization positive regulation of actin filament polymerization po... | cell cortex; cell pole; cytosol; extracellular matrix; leading edge membrane; lipid droplet; pathogen-containing vacuole; phagocytic vesicle; plasma membrane; vesicle | G protein activity GDP binding GTP binding GTPase activator activity GTPase activity guanylate cyclase activator activity small GTPase binding | Dictyostelium discoideum | Cell membrane GTP-binding Hydrolase Lipoprotein Membrane Methylation Nucleotide-binding Prenylation Reference proteome | MPLREFKIVV | MPLREFKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDSNQCMLEILDTAGTEQFTAMRDLYMKNGQGFVLVYSIISNSTFNELPDLREQILRVKDCEDVPMVLVGNKCDLHDQRVISTEQGEELARKFGDCYFLEASAKNKVNVEQIFYNLIRQINRKNPVGPPSKAKSKCALL | actomyosin structure organization cellular response to cGMP chemotaxis hyperosmotic response microtubule cytoskeleton organization involved in mitosis mitotic cytokinesis negative regulation of cell migration negative regulation of pinocytosis nucleus organization positive regulation of actin filament polymerization po... |
localization negative regulation of transcription by RNA polymerase II negative regulation of transcription elongation by RNA polymerase II positive regulation of ERK1 and ERK2 cascade positive regulation of protein modification process positive regulation of transcription by RNA polymerase II | chromatin; NELF complex; nuclear body; nucleoplasm; nucleus; plasma membrane | chromatin binding mRNA binding RNA binding | Homo sapiens | 3D-structure ADP-ribosylation Alternative splicing Chromosome Coiled coil Direct protein sequencing Isopeptide bond Nucleus Phosphoprotein Reference proteome Repeat Repressor RNA-binding Transcription Transcription regulation Ubl conjugation | MLVIPPGLSE | MLVIPPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSSTTSQGGVKRSLSEQPVMDTATATEQAKQLVKSGAISAIKAETKNSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSISADDDLQESSRRPQRKSLYESFVSSSDRLRELGPDGEEAEGPGAGDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNTLYVYGEDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQV... | localization negative regulation of transcription by RNA polymerase II negative regulation of transcription elongation by RNA polymerase II positive regulation of ERK1 and ERK2 cascade positive regulation of protein modification process positive regulation of transcription by RNA polymerase II chromatin; NELF complex; ... |
cytoplasmic translation translation | cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; nucleus | RNA binding structural constituent of ribosome | Homo sapiens | 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein | MVRYSLDPEN | MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE | cytoplasmic translation translation cytoplasm; cytosol; cytosolic large ribosomal subunit; cytosolic ribosome; nucleus RNA binding structural constituent of ribosome Homo sapiens 3D-structure Alternative splicing Cytoplasm Direct protein sequencing Reference proteome Ribonucleoprotein Ribosomal protein MVRYSLDPEN MVRYS... |
adaptive immune response cell surface receptor signaling pathway natural killer cell mediated cytotoxicity negative regulation of interleukin-2 production negative regulation of regulatory T cell differentiation plasmacytoid dendritic cell activation positive regulation of natural killer cell mediated cytotoxicity regu... | external side of plasma membrane; extracellular region; plasma membrane | antigen binding MHC class II protein binding transmembrane signaling receptor activity | Homo sapiens | 3D-structure Adaptive immunity Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunity Immunoglobulin domain Membrane Reference proteome Repeat Secreted Signal Transmembrane Transmembrane helix | MWEAQFLGLL | MWEAQFLGLLFLQPLWVAPVKPLQPGAEVPVVWAQEGAPAQLPCSPTIPLQDLSLLRRAGVTWQHQPDSGPPAAAPGHPLAPGPHPAAPSSWGPRPRRYTVLSVGPGGLRSGRLPLQPRVQLDERGRQRGDFSLWLRPARRADAGEYRAAVHLRDRALSCRLRLRLGQASMTASPPGSLRASDWVILNCSFSRPDRPASVHWFRNRGQGRVPVRESPHHHLAESFLFLPQVSPMDSGPWGCILTYRDGFNVSIMYNLTVLGLEPPTPLTVYAGAGSRVGLPCRLPAGVGTRSFLTAKWTPPGGGPDLLVTGDNGDFTLRL... | adaptive immune response cell surface receptor signaling pathway natural killer cell mediated cytotoxicity negative regulation of interleukin-2 production negative regulation of regulatory T cell differentiation plasmacytoid dendritic cell activation positive regulation of natural killer cell mediated cytotoxicity regu... |
cholesterol metabolic process lipid transport lipoprotein metabolic process peptidyl-methionine modification phosphatidylcholine metabolic process positive regulation of cholesterol efflux positive regulation of phagocytosis positive regulation of phospholipid efflux protein oxidation protein stabilization regulation o... | extracellular space; high-density lipoprotein particle | high-density lipoprotein particle receptor binding lipid binding protein homodimerization activity | Sus scrofa | Cholesterol metabolism Direct protein sequencing Glycoprotein HDL Lipid metabolism Lipid transport Lipoprotein Oxidation Palmitate Phosphoprotein Reference proteome Repeat Secreted Signal Steroid metabolism Sterol metabolism Transport | MKAVVLTLAV | MKAVVLTLAVLFLTGSQARHFWQQDDPQSPWDRVKDFATVYVDAIKDSGRDYVAQFEASALGKHLNLKLLDNWDSLGSTFTKVREQLGPVTQEFWDNLEKETEALRQEMSKDLEEVKKKVQPYLDDFQNKWQEEMETYRQKMAPLGAEFREGARQKVQELQEKLSPLAEELRDRLRAHVEALRQHVAPYSDDLRQRMAARFEALKEGGGSLAEYQAKAQEQLKALGEKAKPALEDLRQGLLPVLENLKVSILAAIDEASKKLNAQ | cholesterol metabolic process lipid transport lipoprotein metabolic process peptidyl-methionine modification phosphatidylcholine metabolic process positive regulation of cholesterol efflux positive regulation of phagocytosis positive regulation of phospholipid efflux protein oxidation protein stabilization regulation o... |
cholesterol catabolic process cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle assembly intermediate-density lipoprotein particle clearance lipoprotein biosynthetic process lipoprotein catabolic process melanosome organization negative regulation of amyloid fibril formation negative re... | chylomicron; extracellular exosome; extracellular matrix; extracellular space; high-density lipoprotein particle; intermediate-density lipoprotein particle; low-density lipoprotein particle; multivesicular body, internal vesicle; very-low-density lipoprotein particle | amyloid-beta binding heparan sulfate proteoglycan binding heparin binding identical protein binding lipid binding low-density lipoprotein particle receptor binding very-low-density lipoprotein particle receptor binding | Sus scrofa | Chylomicron Direct protein sequencing Endosome Extracellular matrix Glycoprotein HDL Heparin-binding Lipid transport Lipid-binding Oxidation Reference proteome Repeat Secreted Signal Transport VLDL | MRVLWVALVV | MRVLWVALVVTLLAGCRTEDEPGPPPEVHVWWEESKWQGSQPWEQALGRFWDYLRWVQSLSDQVQEELLSTKVTQELTELIEESMKEVKAYREELEAQLGPVTQETQARLSKELQAAQARVGADMEDVRNRLVLYRSEVHNMLGQTTEELRSRLASHLRNVRKRLVRDTEDLQKRLAVYQAGLREGAERSVSALRERLGPLVEQGRLRAATLSTRAGQPLRERAEAWGQKLRGRLEEMGSRTRDRLDEMRDELEEVRTKVEEQGSQLRLQAEAFQARLKGWFEPLVEDMRRQWAGLVERMQSAVSISSSTSAPSDNQ | cholesterol catabolic process cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle assembly intermediate-density lipoprotein particle clearance lipoprotein biosynthetic process lipoprotein catabolic process melanosome organization negative regulation of amyloid fibril formation negative re... |
activation of protein kinase B activity angiogenesis branch elongation involved in ureteric bud branching cell differentiation cellular response to heat fibroblast growth factor receptor signaling pathway mesonephric epithelium development positive regulation of angiogenesis positive regulation of cell division positiv... | cell cortex; cytosol; extracellular region; extracellular space; nucleus | fibroblast growth factor receptor binding growth factor activity heparin binding integrin binding S100 protein binding | Canis lupus familiaris | Angiogenesis Cytoplasm Developmental protein Differentiation Direct protein sequencing Growth factor Heparin-binding Mitogen Nucleus Phosphoprotein Reference proteome Secreted | NYMKPKLLYX | NYMKPKLLYXSNGGH | activation of protein kinase B activity angiogenesis branch elongation involved in ureteric bud branching cell differentiation cellular response to heat fibroblast growth factor receptor signaling pathway mesonephric epithelium development positive regulation of angiogenesis positive regulation of cell division positiv... |
hepatocyte proliferation intracellular signal transduction negative regulation of apoptotic process negative regulation of TOR signaling phosphorylation positive regulation of DNA-templated transcription positive regulation of hepatic stellate cell activation positive regulation of transcription by RNA polymerase II | cytoplasm; cytosol; nucleoplasm; spindle; synapse | ATP binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process DNA-binding transcription factor binding kinase activity magnesium ion binding protein serine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity ribosomal protein S6 kinase ac... | Mus musculus | ATP-binding Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Transferase | MPLAQLKEPW | MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKDEAILKEISITHHVKAGSEKADPSQFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYR... | hepatocyte proliferation intracellular signal transduction negative regulation of apoptotic process negative regulation of TOR signaling phosphorylation positive regulation of DNA-templated transcription positive regulation of hepatic stellate cell activation positive regulation of transcription by RNA polymerase II cy... |
cell cycle intracellular signal transduction phosphorylation positive regulation of transcription by RNA polymerase II response to lipopolysaccharide toll-like receptor signaling pathway | cytoplasm; cytosol; nucleolus; nucleoplasm | ATP binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process magnesium ion binding protein kinase binding protein serine kinase activity protein serine/threonine kinase activity ribosomal protein S6 kinase activity | Mus musculus | 3D-structure ATP-binding Cell cycle Cytoplasm Kinase Nucleotide-binding Nucleus Phosphoprotein Reference proteome Repeat Serine/threonine-protein kinase Stress response Transferase | MPLAQLADPW | MPLAQLADPWQKMAVESPSDSAENGQQIMDEPMGEEEINPQTEEGSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEE... | cell cycle intracellular signal transduction phosphorylation positive regulation of transcription by RNA polymerase II response to lipopolysaccharide toll-like receptor signaling pathway cytoplasm; cytosol; nucleolus; nucleoplasm ATP binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process m... |
cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle clearance lipid catabolic process negative regulation of cholesterol transport negative regulation of lipid metabolic process negative regulation of receptor-mediated endocytosis negative regulation of very-low-density lipoprotein partic... | chylomicron; intermediate-density lipoprotein particle; low-density lipoprotein particle; spherical high-density lipoprotein particle; very-low-density lipoprotein particle | lipase inhibitor activity lipid binding lipoprotein lipase activator activity phospholipase activator activity phospholipase binding | Macaca fascicularis | Chylomicron Direct protein sequencing Glycoprotein HDL LDL Lipid degradation Lipid metabolism Lipid transport Reference proteome Secreted Sialic acid Signal Transport VLDL | MGTRFLLALC | MGTRFLLALCLVLLVLGFEVQGAQLPQQDEPPSPALLSRVQESLSSYWESAKAAAQKLYEKTYLPAVDEKLRDLYSKSTAAMSTYTGIFTDQVLSVLKGEE | cholesterol efflux chylomicron remnant clearance high-density lipoprotein particle clearance lipid catabolic process negative regulation of cholesterol transport negative regulation of lipid metabolic process negative regulation of receptor-mediated endocytosis negative regulation of very-low-density lipoprotein partic... |
regulation of cell shape | apical part of cell; cell cortex; cytoplasm; myofibril; myosin II complex; protein-containing complex; stress fiber; Z disc | calcium ion binding GTPase binding myosin heavy chain binding | Rattus norvegicus | Calcium Metal-binding Motor protein Muscle protein Myosin Phosphoprotein Reference proteome Repeat | MSSKKAKTKT | MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAPGRINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD | regulation of cell shape apical part of cell; cell cortex; cytoplasm; myofibril; myosin II complex; protein-containing complex; stress fiber; Z disc calcium ion binding GTPase binding myosin heavy chain binding Rattus norvegicus Calcium Metal-binding Motor protein Muscle protein Myosin Phosphoprotein Reference proteome... |
canonical glycolysis gluconeogenesis glycolytic process regulation of glycolytic process regulation of pentose-phosphate shunt respiratory burst | cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; secretory granule lumen | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity bisphosphoglycerate mutase activity hydrolase activity phosphoglycerate mutase activity protein kinase binding | Homo sapiens | 3D-structure Acetylation Direct protein sequencing Glycolysis Hydrolase Isomerase Phosphoprotein Reference proteome | MAAYKLVLIR | MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQKRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDVPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVRKAMEAVAAQGKAKK | canonical glycolysis gluconeogenesis glycolytic process regulation of glycolytic process regulation of pentose-phosphate shunt respiratory burst cytoplasm; cytosol; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; membrane; secretory granule lumen 2,3-bisphosphoglycerate-dependent phosphoglyce... |
cellular response to interleukin-7 positive regulation of interferon-alpha production positive regulation of T cell activation positive regulation of type II interferon production protein refolding response to cold T cell activation | cytoplasm; migrasome; mitochondrial matrix; protein-containing complex; secretory granule; sperm plasma membrane | ATP binding ATP-dependent protein folding chaperone isomerase activity lipopolysaccharide binding | Cricetulus griseus | Acetylation ATP-binding Chaperone Isomerase Isopeptide bond Mitochondrion Nucleotide-binding Phosphoprotein Transit peptide Ubl conjugation | MLRLPTVLRQ | MLRLPTVLRQMRPVSRALAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKAIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIAT... | cellular response to interleukin-7 positive regulation of interferon-alpha production positive regulation of T cell activation positive regulation of type II interferon production protein refolding response to cold T cell activation cytoplasm; migrasome; mitochondrial matrix; protein-containing complex; secretory granu... |
cytoplasmic microtubule organization meiotic spindle organization microtubule nucleation microtubule nucleation by spindle pole body mitotic cell cycle mitotic cytokinesis, division site positioning mitotic sister chromatid segregation mitotic spindle midzone assembly mitotic spindle organization | cytoplasm; equatorial microtubule organizing center; gamma-tubulin complex; gamma-tubulin ring complex; gamma-tubulin small complex; half bridge of mitotic spindle pole body; inner plaque of mitotic spindle pole body; interphase microtubule organizing center; mating projection tip; microtubule; microtubule organizing c... | GTP binding structural constituent of cytoskeleton | Emericella nidulans | Cytoplasm Cytoskeleton GTP-binding Microtubule Nucleotide-binding Reference proteome | MPREIITIQA | MPREIITIQAGQCGNNVGSQFWQQLCLEHGISQDGNLEEFATEGGDRKDVFFYQSDDTRYIPRAILLDLEPRVLNGIQSGPYKNIYNPENFFIGQQGIGAGNNWGAGYAAGEVVQEEVFDMIDREADGSDSLEGFMFLHSIAGGTGSGLGSFLLERMNDRFPKKLIQTYSVFPDTQAADVVVNPYNSLLAMRRLTQNADSVVVLDNAALSRIVADRLHVQEPSFQQTNRLVSTVMSASTTTLRYPGYMHNDLVGIIASLIPTPRSHFLLTSYTPFTGDNIDQAKTVRKTTVLDVMRRLLQPKNRMVSINPSKSSCYISIL... | cytoplasmic microtubule organization meiotic spindle organization microtubule nucleation microtubule nucleation by spindle pole body mitotic cell cycle mitotic cytokinesis, division site positioning mitotic sister chromatid segregation mitotic spindle midzone assembly mitotic spindle organization cytoplasm; equatorial ... |
intracellular protein transport positive regulation of protein catabolic process positive regulation of receptor recycling potassium ion transport SNARE complex disassembly | cytosol; Golgi apparatus; midbody; plasma membrane | ATP binding ATP hydrolysis activity ATP-dependent protein disaggregase activity identical protein binding ionotropic glutamate receptor binding metal ion binding PDZ domain binding protein kinase binding protein-containing complex binding SNARE binding syntaxin-1 binding | Cricetulus griseus | 3D-structure Acetylation ATP-binding Cytoplasm Direct protein sequencing Hydrolase Magnesium Metal-binding Nucleotide-binding Phosphoprotein Protein transport Repeat Transport | MAGRSMQAAR | MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMDPSILKGEPASGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANS... | intracellular protein transport positive regulation of protein catabolic process positive regulation of receptor recycling potassium ion transport SNARE complex disassembly cytosol; Golgi apparatus; midbody; plasma membrane ATP binding ATP hydrolysis activity ATP-dependent protein disaggregase activity identical protei... |
cell division chromosome segregation G1/S transition of mitotic cell cycle mitotic nuclear membrane reassembly mitotic spindle organization regulation of mitotic nuclear division spindle assembly viral process | chromatin; chromosome; condensed nuclear chromosome; cytoplasm; nucleoplasm; nucleus; protein-containing complex | chromatin binding guanyl-nucleotide exchange factor activity histone binding nucleosomal DNA binding nucleosome binding protein heterodimerization activity small GTPase binding sulfate binding | Homo sapiens | 3D-structure Alternative splicing Cell cycle Cell division Chromosome Cytoplasm Direct protein sequencing DNA-binding Guanine-nucleotide releasing factor Methylation Mitosis Nucleus Phosphoprotein Reference proteome Repeat | MSPKRIAKRR | MSPKRIAKRRSPPADAIPKSKKVKVSHRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPEDVVQAEAGGMHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIGLLEPMKKSMVPVQVQLDVPVVKVASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPGTESCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGR... | cell division chromosome segregation G1/S transition of mitotic cell cycle mitotic nuclear membrane reassembly mitotic spindle organization regulation of mitotic nuclear division spindle assembly viral process chromatin; chromosome; condensed nuclear chromosome; cytoplasm; nucleoplasm; nucleus; protein-containing compl... |
cellular response to leukemia inhibitory factor cysteine biosynthetic process cysteine biosynthetic process via cystathionine glutathione metabolic process homocysteine metabolic process hydrogen sulfide biosynthetic process lipid metabolic process negative regulation of apoptotic process negative regulation of apoptot... | cytoplasm; cytosol | calmodulin binding cystathionine beta-lyase activity cystathionine gamma-lyase activity homocysteine desulfhydrase activity identical protein binding L-cysteine desulfhydrase activity L-cystine L-cysteine-lyase (deaminating) pyridoxal phosphate binding selenocystathionine gamma-lyase activity | Rattus norvegicus | Amino-acid biosynthesis Calmodulin-binding Cysteine biosynthesis Cytoplasm Direct protein sequencing Lipid metabolism Lyase Phosphoprotein Pyridoxal phosphate Reference proteome | MQKDASSSGF | MQKDASSSGFLPSFQHFATQAIHVGPEPEQWSSRAVVLPISLATTFKQDSPGQSSGFVYSRSGNPTRNCLEKAVAALDGAKHCLTFARGLAATTTITHLLKAGDEVICMDEVYGGTNRYFRRVASEFGLKISFVDCSKTKLLEAAITPQTKLVWIETPTNPTLKLADIKACAQIVHKHKDIILVVDNTFMSAYFQRPLALGADICMCSATKYMNGHSDVVMGLVSVTSDDLNERLRFLQNSLGAVPSPFDCYLCCRGLKTLQIRMEKHFRNGMAVARFLESNPRVEKVIYPGLPSHPQHELAKRQCTGCPGMVSFYIKGT... | cellular response to leukemia inhibitory factor cysteine biosynthetic process cysteine biosynthetic process via cystathionine glutathione metabolic process homocysteine metabolic process hydrogen sulfide biosynthetic process lipid metabolic process negative regulation of apoptotic process negative regulation of apoptot... |
autophagosome assembly endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to plasma membrane protein transport inter-Golgi cisterna vesicle-mediated transport intra-Golgi vesicle-mediated transport macroautophagy SNARE complex disassembly vacuole fusion, non-autophagic vesicle fusion with Golgi apparatus | cytosol; Golgi apparatus; Golgi stack; mating projection tip | ATP binding ATP hydrolysis activity phosphatidic acid binding SNARE binding | Saccharomyces cerevisiae | 3D-structure ATP-binding Cytoplasm ER-Golgi transport Nucleotide-binding Phosphoprotein Protein transport Reference proteome Repeat Transport | MFKIPGFGKA | MFKIPGFGKAAANHTPPDMTNMDTRTRHLKVSNCPNNSYALANVAAVSPNDFPNNIYIIIDNLFVFTTRHSNDIPPGTIGFNGNQRTWGGWSLNQDVQAKAFDLFKYSGKQSYLGSIDIDISFRARGKAVSTVFDQDELAKQFVRCYESQIFSPTQYLIMEFQGHFFDLKIRNVQAIDLGDIEPTSAVATGIETKGILTKQTQINFFKGRDGLVNLKSSNSLRPRSNAVIRPDFKFEDLGVGGLDKEFTKIFRRAFASRIFPPSVIEKLGISHVKGLLLYGPPGTGKTLIARKIGTMLNAKEPKIVNGPEILSKYVGSSE... | autophagosome assembly endoplasmic reticulum to Golgi vesicle-mediated transport Golgi to plasma membrane protein transport inter-Golgi cisterna vesicle-mediated transport intra-Golgi vesicle-mediated transport macroautophagy SNARE complex disassembly vacuole fusion, non-autophagic vesicle fusion with Golgi apparatus c... |
detection of chemical stimulus involved in sensory perception of bitter taste one-carbon metabolic process | cytoplasm; cytosol; extracellular space | carbonate dehydratase activity zinc ion binding | Mus musculus | Direct protein sequencing Disulfide bond Glycoprotein Lyase Metal-binding Reference proteome Secreted Signal Zinc | MRALVSVVSL | MRALVSVVSLFFLGIQAHSDWSYSGDDGVGESQWSEQYPSCGGERQSPIDVKTEEVMFNPSLKPLSLVNYEKENLEFTMTNNGHTVSIDLPPSMYLETSDGTEFISKAFHFHWGGRDWELSGSEHTIDGIRSIMEAHFVHFNKEYGTYENAKDQKNGLAVLAVLFKIDEYAENTYYSDIISALKNIEKPGETTTLKDTTIRNLLPKDVHHYYTYPGSLTTPPCTENVQWFVLRDKVTLSKAQVVTIENSVMDHNNNTIQNGYRSTQPNNHRVVEANFLNVQDMYSSYHLYLKNMQKEILQPKKQKKTKKNRHFWSRK | detection of chemical stimulus involved in sensory perception of bitter taste one-carbon metabolic process cytoplasm; cytosol; extracellular space carbonate dehydratase activity zinc ion binding Mus musculus Direct protein sequencing Disulfide bond Glycoprotein Lyase Metal-binding Reference proteome Secreted Signal Zin... |
anaerobic electron transport chain anaerobic respiration dimethyl sulfoxide metabolic process | dimethyl sulfoxide reductase complex; outer membrane-bounded periplasmic space; plasma membrane | 4 iron, 4 sulfur cluster binding dimethyl sulfoxide reductase activity electron transfer activity molybdenum ion binding molybdopterin cofactor binding | Escherichia coli | 4Fe-4S Cell membrane Direct protein sequencing Iron Iron-sulfur Membrane Metal-binding Molybdenum Oxidoreductase Reference proteome Signal | MKTKIPDAVL | MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAHAVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVRACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGNESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYGGWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTDTGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCV... | anaerobic electron transport chain anaerobic respiration dimethyl sulfoxide metabolic process dimethyl sulfoxide reductase complex; outer membrane-bounded periplasmic space; plasma membrane 4 iron, 4 sulfur cluster binding dimethyl sulfoxide reductase activity electron transfer activity molybdenum ion binding molybdopt... |
anaerobic electron transport chain anaerobic respiration dimethyl sulfoxide metabolic process | dimethyl sulfoxide reductase complex; plasma membrane | 4 iron, 4 sulfur cluster binding dimethyl sulfoxide reductase activity metal ion binding | Escherichia coli | 4Fe-4S Direct protein sequencing Electron transport Iron Iron-sulfur Metal-binding Reference proteome Repeat Transport | MTTQYGFFID | MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRKKHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV | anaerobic electron transport chain anaerobic respiration dimethyl sulfoxide metabolic process dimethyl sulfoxide reductase complex; plasma membrane 4 iron, 4 sulfur cluster binding dimethyl sulfoxide reductase activity metal ion binding Escherichia coli 4Fe-4S Direct protein sequencing Electron transport Iron Iron-sulf... |
clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... | host cell endosome membrane; host cell plasma membrane; membrane; viral envelope; virion membrane | structural molecule activity | Human immunodeficiency virus type 1 group M subtype D | AIDS Apoptosis Clathrin-mediated endocytosis of virus by host Cleavage on pair of basic residues Coiled coil Disulfide bond Fusion of virus membrane with host endosomal membrane Fusion of virus membrane with host membrane Glycoprotein Host cell membrane Host endosome Host membrane Host-virus interaction Lipoprotein Mem... | MRAREKERNC | MRAREKERNCQNLWKWGIMLLGMLMTCSAAEDLWVTVYYGVPIWKEATTTLFCASDAKAYKKEAHNIWATHACVPTDPNPQEIELENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDELRNSKGNGKVEEEEKRKNCSFNVRDKREQVYALFYKLDIVPIDNNNRTNSTNYRLINCDTSTITQACPKISFEPIPIHFCAPAGFAILKCRDKKFNGTGPCSNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIIIRSENLTNNVKTIIVQLNASIVINCTRPYKYTRQRTSIGLRQSLYTITGKKKKT... | clathrin-dependent endocytosis of virus by host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane positive regulation of establishment of T cell polarity positive regulation of plasma membrane raft polarization positive regulation of receptor clustering viral p... |
viral budding via host ESCRT complex | host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane | RNA binding structural molecule activity zinc ion binding | Human immunodeficiency virus type 1 group M subtype D | AIDS Capsid protein Host cell membrane Host cytoplasm Host endosome Host membrane Host nucleus Host-virus interaction Lipoprotein Membrane Metal-binding Methylation Myristate Phosphoprotein Repeat Ribosomal frameshifting RNA-binding Viral budding Viral budding via the host ESCRT complexes Viral nucleoprotein Viral rele... | MGARASVLSG | MGARASVLSGGKLDTWERIRLRPGGKKKYALKHLIWASRELERFTLNPGLLETSEGCKQIIGQLQPSIQTGSEEIRSLYNTVATLYCVHERIEVKDTKEAVEKMEEEQNKSKKKTQQAAADSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINDEAAEWDRLHPVHAGPVAPGQMREPRGSDIAGTTSTLQEQIAWMTSNPPIPVGEIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFYKTLRAEQASQDVKNWMTETLLV... | viral budding via host ESCRT complex host cell nucleus; host cell plasma membrane; host multivesicular body; membrane; viral nucleocapsid; virion membrane RNA binding structural molecule activity zinc ion binding Human immunodeficiency virus type 1 group M subtype D AIDS Capsid protein Host cell membrane Host cytoplas... |
suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy | extracellular region; host cell Golgi membrane; host cell plasma membrane; membrane; virion component | GTP binding SH3 domain binding | Human immunodeficiency virus type 1 group M subtype D | AIDS Apoptosis Early protein Host cell membrane Host Golgi apparatus Host membrane Host-virus interaction Inhibition of host adaptive immune response by virus Inhibition of host autophagy by virus Inhibition of host MHC class I molecule presentation by virus Inhibition of host MHC class II molecule presentation by viru... | MGGKWSKSSL | MGGKWSKSSLVGWPAIRERIRKTDPAADGVGAVSRDLEKHGAITSSNTASTNDTCAWLEAQEESEEVGFPVRPQVPLRPMTYKEAVDLSHFLKEKGGLEGLIWSKKRQEILDLWVYNTQGIFPDWQNYTPGPGIRYPLTFGWCFQLVPVDPQEVEEATEREDNCLLHPMCQQGMEDPERQVLMWRFNSRLALEHKARELHPEFYKDC | suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II suppression by virus of host autophagy extracellular region; host cell Golgi membrane; host cell plasma membrane; membr... |
DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... | extracellular region; host cell cytoplasm; host cell nucleolus | actinin binding cyclin binding metal ion binding protein domain specific binding protein serine/threonine phosphatase inhibitor activity RNA-binding transcription regulator activity trans-activation response element binding | Human immunodeficiency virus type 1 group M subtype D | Acetylation Activator AIDS Alternative splicing Apoptosis Host cytoplasm Host nucleus Host-virus interaction Inhibition of host innate immune response by virus Inhibition of host interferon signaling pathway by virus Isopeptide bond Metal-binding Methylation Modulation of host chromatin by virus Modulation of host PP1 ... | MDPVDPNLES | MDPVDPNLESWNHPGSQPRTACNKCHCKKCCYHCQVCFITKGLGISYGRKKRRQRRKPPQGDQAHQVPIPEQPSSQSRGDPTGPKK | DNA-templated transcription modulation by virus of host chromatin organization negative regulation of peptidyl-threonine phosphorylation positive regulation of transcription elongation by RNA polymerase II positive regulation of viral transcription suppression by virus of host translation initiation suppression by viru... |
fatty acid biosynthetic process malonyl-CoA biosynthetic process | acetyl-CoA carboxylase complex; chloroplast inner membrane; chloroplast stroma | acetyl-CoA carboxylase activity ATP binding carboxyl- or carbamoyltransferase activity zinc ion binding | Pisum sativum | ATP-binding Chloroplast Direct protein sequencing Disulfide bond Fatty acid biosynthesis Fatty acid metabolism Lipid biosynthesis Lipid metabolism Membrane Metal-binding Nucleotide-binding Plastid Plastid inner membrane RNA editing Transferase Zinc Zinc-finger | MINEDPSSLT | MINEDPSSLTDMDNNIDSWKNNSENSSYSHADSLADVSNIDNLLSDKIFSIRDSNSNIYDIYYAYDTNDTNITKYKWTNNINRCIESYLRSQICEDIDFNSDICDKVQRTIIILIRSTNDTNDISDTNDISDTNDTNDTNAIYDPFDISDTNDTNEIYDPFFILDINDTNDTNDIYGIYDPDDIYETNIKDICERYSEIYPRNREKSTFVPIDYSDPNCMEKLARLWVQCETCYGLNFKQFFRPKMNICEHCGEHLKMSSSDRIDLLIDRDTWNPMDEDMVSVDPIKFDSIKELGSEEESSKDRLDEDMLSPDPIELDSE... | fatty acid biosynthetic process malonyl-CoA biosynthetic process acetyl-CoA carboxylase complex; chloroplast inner membrane; chloroplast stroma acetyl-CoA carboxylase activity ATP binding carboxyl- or carbamoyltransferase activity zinc ion binding Pisum sativum ATP-binding Chloroplast Direct protein sequencing Disulfi... |
activation of protein kinase B activity adenylate cyclase-activating adrenergic receptor signaling pathway adrenergic receptor signaling pathway cell-cell signaling G protein-coupled receptor signaling pathway negative regulation of epinephrine secretion negative regulation of norepinephrine secretion platelet activati... | cytoplasm; endosome; plasma membrane | alpha-2A adrenergic receptor binding alpha2-adrenergic receptor activity epinephrine binding protein heterodimerization activity protein homodimerization activity | Homo sapiens | 3D-structure Cell membrane Disulfide bond G-protein coupled receptor Glycoprotein Membrane Receptor Reference proteome Transducer Transmembrane Transmembrane helix | MASPALAAAL | MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADG... | activation of protein kinase B activity adenylate cyclase-activating adrenergic receptor signaling pathway adrenergic receptor signaling pathway cell-cell signaling G protein-coupled receptor signaling pathway negative regulation of epinephrine secretion negative regulation of norepinephrine secretion platelet activati... |
canonical Wnt signaling pathway cell migration myoblast development positive regulation of exosomal secretion positive regulation of extracellular exosome assembly receptor-mediated endocytosis response to calcium ion response to cAMP response to glucocorticoid response to hydrogen peroxide response to toxic substance ... | cell surface; external side of plasma membrane; extracellular exosome; Golgi lumen; lysosomal lumen; plasma membrane; protein-containing complex | cargo receptor activity identical protein binding | Homo sapiens | 3D-structure Glycoprotein Heparan sulfate Membrane Phosphoprotein Proteoglycan Reference proteome Secreted Signal Transmembrane Transmembrane helix | MRRAALWLWL | MRRAALWLWLCALALSLQPALPQIVATNLPPEDQDGSGDDSDNFSGSGAGALQDITLSQQTPSTWKDTQLLTAIPTSPEPTGLEATAASTSTLPAGEGPKEGEAVVLPEVEPGLTAREQEATPRPRETTQLPTTHLASTTTATTAQEPATSHPHRDMQPGHHETSTPAGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVAVEPDRRNQSPVDQGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA | canonical Wnt signaling pathway cell migration myoblast development positive regulation of exosomal secretion positive regulation of extracellular exosome assembly receptor-mediated endocytosis response to calcium ion response to cAMP response to glucocorticoid response to hydrogen peroxide response to toxic substance ... |
canonical Wnt signaling pathway cell migration myoblast development positive regulation of exosomal secretion positive regulation of extracellular exosome assembly receptor-mediated endocytosis response to calcium ion response to cAMP response to glucocorticoid response to hydrogen peroxide response to toxic substance ... | cell surface; external side of plasma membrane; extracellular region; Golgi lumen; plasma membrane; protein-containing complex | cargo receptor activity identical protein binding | Mus musculus | Alternative splicing Glycoprotein Heparan sulfate Membrane Phosphoprotein Proteoglycan Reference proteome Secreted Signal Transmembrane Transmembrane helix | MRRAALWLWL | MRRAALWLWLCALALRLQPALPQIVAVNVPPEDQDGSGDDSDNFSGSGTGALPDTLSRQTPSTWKDVWLLTATPTAPEPTSSNTETAFTSVLPAGEKPEEGEPVLHVEAEPGFTARDKEKEVTTRPRETVQLPITQRASTVRVTTAQAAVTSHPHGGMQPGLHETSAPTAPGQPDHQPPRVEGGGTSVIKEVVEDGTANQLPAGEGSGEQDFTFETSGENTAVAAVEPGLRNQPPVDEGATGASQSLLDRKEVLGGVIAGGLVGLIFAVCLVAFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA | canonical Wnt signaling pathway cell migration myoblast development positive regulation of exosomal secretion positive regulation of extracellular exosome assembly receptor-mediated endocytosis response to calcium ion response to cAMP response to glucocorticoid response to hydrogen peroxide response to toxic substance ... |
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