row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:12838 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,838 | train | mutant | 3,786,979 | 225 | 3,790,924 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241D | T241D | 1 | 1 | 0 | 0 | 241 | T | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,081 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.743555 | 0.085956 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182844,"numValue":-0.743554840638508,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182845,"numValue":0.0859556289001576,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12839 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,839 | train | mutant | 3,786,980 | 225 | 3,790,925 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241E | T241E | 1 | 1 | 0 | 0 | 241 | T | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,207 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.334353 | 0.066501 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673096,"numValue":0.334352978616808,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673097,"numValue":0.0665006169564842,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12840 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,840 | train | mutant | 3,786,980 | 225 | 3,790,925 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241E | T241E | 1 | 1 | 0 | 0 | 241 | T | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,082 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.685698 | 0.053294 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182846,"numValue":-0.68569797724766,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182847,"numValue":0.0532941131261342,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12841 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,841 | train | mutant | 3,786,981 | 225 | 3,790,926 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241F | T241F | 1 | 1 | 0 | 0 | 241 | T | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,208 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.517848 | 0.064767 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673098,"numValue":0.517847786831933,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673099,"numValue":0.0647672211748773,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12842 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,842 | train | mutant | 3,786,981 | 225 | 3,790,926 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241F | T241F | 1 | 1 | 0 | 0 | 241 | T | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,083 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.679621 | 0.065669 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182848,"numValue":-0.679621370652541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182849,"numValue":0.0656690294806924,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12843 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,843 | train | mutant | 3,786,982 | 225 | 3,790,927 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241G | T241G | 1 | 1 | 0 | 0 | 241 | T | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,209 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.257676 | 0.085475 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673100,"numValue":0.257675985332345,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673101,"numValue":0.0854754724865995,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12844 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,844 | train | mutant | 3,786,982 | 225 | 3,790,927 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241G | T241G | 1 | 1 | 0 | 0 | 241 | T | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,084 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.457875 | 0.042928 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182850,"numValue":-0.457874841215542,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182851,"numValue":0.0429277894063261,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12845 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,845 | train | mutant | 3,786,983 | 225 | 3,790,928 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241H | T241H | 1 | 1 | 0 | 0 | 241 | T | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,210 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.244987 | 0.117304 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673102,"numValue":0.244987242209658,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673103,"numValue":0.117303973138363,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12846 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,846 | train | mutant | 3,786,983 | 225 | 3,790,928 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241H | T241H | 1 | 1 | 0 | 0 | 241 | T | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,085 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.587541 | 0.093081 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182852,"numValue":-0.587540677623233,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182853,"numValue":0.0930809551972979,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12847 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,847 | train | mutant | 3,786,984 | 225 | 3,790,929 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241I | T241I | 1 | 1 | 0 | 0 | 241 | T | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,211 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.579656 | 0.108132 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673104,"numValue":0.579655862042413,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673105,"numValue":0.108131799492718,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12848 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,848 | train | mutant | 3,786,984 | 225 | 3,790,929 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241I | T241I | 1 | 1 | 0 | 0 | 241 | T | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,086 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.758059 | 0.067553 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182854,"numValue":-0.758059000134961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182855,"numValue":0.067552579398316,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12849 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,849 | train | mutant | 3,786,985 | 225 | 3,790,930 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241K | T241K | 1 | 1 | 0 | 0 | 241 | T | K | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,212 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.407208 | 0.12745 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673106,"numValue":0.407207551149738,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673107,"numValue":0.12745035286066,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12850 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,850 | train | mutant | 3,786,985 | 225 | 3,790,930 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241K | T241K | 1 | 1 | 0 | 0 | 241 | T | K | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,087 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.597452 | 0.069451 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182856,"numValue":-0.597452192773635,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182857,"numValue":0.0694514145249501,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12851 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,851 | train | mutant | 3,786,986 | 225 | 3,790,931 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241L | T241L | 1 | 1 | 0 | 0 | 241 | T | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,213 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.333924 | 0.11999 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673108,"numValue":0.333924055400113,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673109,"numValue":0.119989562256991,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12852 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,852 | train | mutant | 3,786,986 | 225 | 3,790,931 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241L | T241L | 1 | 1 | 0 | 0 | 241 | T | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,088 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.395538 | 0.04771 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182858,"numValue":-0.395537605367834,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182859,"numValue":0.0477099432906413,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12853 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,853 | train | mutant | 3,786,987 | 225 | 3,790,932 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241M | T241M | 1 | 1 | 0 | 0 | 241 | T | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,214 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.286327 | 0.070046 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673110,"numValue":0.286326980439272,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673111,"numValue":0.0700455660109455,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12855 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,855 | train | mutant | 3,786,988 | 225 | 3,790,933 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241N | T241N | 1 | 1 | 0 | 0 | 241 | T | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,215 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.032406 | 0.092032 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673112,"numValue":0.0324058315039852,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673113,"numValue":0.0920319650725856,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12856 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,856 | train | mutant | 3,786,988 | 225 | 3,790,933 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241N | T241N | 1 | 1 | 0 | 0 | 241 | T | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,090 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.032917 | 0.081762 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182862,"numValue":-0.0329169084620035,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182863,"numValue":0.0817617049203291,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12857 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,857 | train | mutant | 3,786,989 | 225 | 3,790,934 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241P | T241P | 1 | 1 | 0 | 0 | 241 | T | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,216 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.810717 | 0.146486 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673114,"numValue":0.810717092574094,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673115,"numValue":0.146486196350212,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12858 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,858 | train | mutant | 3,786,989 | 225 | 3,790,934 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241P | T241P | 1 | 1 | 0 | 0 | 241 | T | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,091 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.866418 | 0.0614 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182864,"numValue":-0.866418400975933,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182865,"numValue":0.0613999764308602,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12859 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,859 | train | mutant | 3,786,990 | 225 | 3,790,935 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241Q | T241Q | 1 | 1 | 0 | 0 | 241 | T | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,217 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.386763 | 0.171327 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673116,"numValue":0.386762631258724,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673117,"numValue":0.171326901230768,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12860 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,860 | train | mutant | 3,786,990 | 225 | 3,790,935 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241Q | T241Q | 1 | 1 | 0 | 0 | 241 | T | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,092 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.691709 | 0.057728 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182866,"numValue":-0.691708859831104,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182867,"numValue":0.0577280331883025,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12861 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,861 | train | mutant | 3,786,991 | 225 | 3,790,936 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241R | T241R | 1 | 1 | 0 | 0 | 241 | T | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,218 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.674284 | 0.06591 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673118,"numValue":0.674283905786132,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673119,"numValue":0.0659098209962768,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12862 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,862 | train | mutant | 3,786,991 | 225 | 3,790,936 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241R | T241R | 1 | 1 | 0 | 0 | 241 | T | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,093 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.51832 | 0.0436 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182868,"numValue":-0.518320084872456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182869,"numValue":0.0435997975334423,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12863 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,863 | train | mutant | 3,786,992 | 225 | 3,790,937 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241S | T241S | 1 | 1 | 0 | 0 | 241 | T | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,219 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033279 | 0.095397 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673120,"numValue":-0.0332787229393612,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673121,"numValue":0.0953965879065276,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12864 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,864 | train | mutant | 3,786,992 | 225 | 3,790,937 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241S | T241S | 1 | 1 | 0 | 0 | 241 | T | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,094 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.072278 | 0.04571 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182870,"numValue":-0.0722781119670046,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182871,"numValue":0.0457100555068321,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12865 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,865 | train | mutant | 3,786,993 | 225 | 3,790,938 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241V | T241V | 1 | 1 | 0 | 0 | 241 | T | V | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,220 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.537371 | 0.092455 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673122,"numValue":0.537370820569059,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673123,"numValue":0.0924552281277252,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12866 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,866 | train | mutant | 3,786,993 | 225 | 3,790,938 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241V | T241V | 1 | 1 | 0 | 0 | 241 | T | V | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,715 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.639162 | 0.049703 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184112,"numValue":-0.639161796376167,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184113,"numValue":0.0497027176039374,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12867 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,867 | train | mutant | 3,786,994 | 225 | 3,790,939 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241W | T241W | 1 | 1 | 0 | 0 | 241 | T | W | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,221 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.682761 | 0.146408 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673124,"numValue":0.682760644751321,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673125,"numValue":0.146408416953256,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12869 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,869 | train | mutant | 3,786,995 | 225 | 3,790,940 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T241Y | T241Y | 1 | 1 | 0 | 0 | 241 | T | Y | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,840,222 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.731952 | 0.058675 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9673126,"numValue":0.731952321130641,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9673127,"numValue":0.0586749338543731,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12871 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,871 | train | mutant | 4,906,048 | 225 | 4,912,636 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delT241 | delT241 | 1 | 0 | 1 | 0 | 241 | T | - | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,078 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.200774 | 0.078118 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182838,"numValue":-1.20077447074735,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182839,"numValue":0.0781183906116703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16905,"numValue":7.0,"position":241,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12873 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,873 | train | mutant | 3,788,285 | 225 | 3,792,230 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242A | Q242A | 1 | 1 | 0 | 0 | 242 | Q | A | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,096 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.024249 | 0.05183 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182874,"numValue":0.024249454961155,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182875,"numValue":0.0518302340980684,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12874 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,874 | train | mutant | 3,788,286 | 225 | 3,792,231 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242C | Q242C | 1 | 1 | 0 | 0 | 242 | Q | C | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,516 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.0525 | 0.099675 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675714,"numValue":0.0525002771172337,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675715,"numValue":0.0996746977997548,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12875 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,875 | train | mutant | 3,788,286 | 225 | 3,792,231 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242C | Q242C | 1 | 1 | 0 | 0 | 242 | Q | C | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,097 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015066 | 0.053551 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182876,"numValue":-0.0150655985114354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182877,"numValue":0.053551081280738,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12876 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,876 | train | mutant | 3,788,287 | 225 | 3,792,232 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242D | Q242D | 1 | 1 | 0 | 0 | 242 | Q | D | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,517 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.19785 | 0.124798 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675716,"numValue":-0.197849698098573,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675717,"numValue":0.124798274599112,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12877 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,877 | train | mutant | 3,788,287 | 225 | 3,792,232 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242D | Q242D | 1 | 1 | 0 | 0 | 242 | Q | D | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,098 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.046856 | 0.053902 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182878,"numValue":0.0468558096304479,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182879,"numValue":0.0539023068980895,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12878 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,878 | train | mutant | 3,788,288 | 225 | 3,792,233 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242E | Q242E | 1 | 1 | 0 | 0 | 242 | Q | E | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,518 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.173284 | 0.081125 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675718,"numValue":-0.173284326881896,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675719,"numValue":0.0811246987221473,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12879 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,879 | train | mutant | 3,788,288 | 225 | 3,792,233 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242E | Q242E | 1 | 1 | 0 | 0 | 242 | Q | E | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,099 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035485 | 0.067397 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182880,"numValue":-0.0354853964727203,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182881,"numValue":0.0673968548665386,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12880 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,880 | train | mutant | 3,788,289 | 225 | 3,792,234 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242F | Q242F | 1 | 1 | 0 | 0 | 242 | Q | F | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,519 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.244098 | 0.106413 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675720,"numValue":0.244098124227637,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675721,"numValue":0.106412560866682,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12881 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,881 | train | mutant | 3,788,289 | 225 | 3,792,234 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242F | Q242F | 1 | 1 | 0 | 0 | 242 | Q | F | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,100 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.163186 | 0.048049 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182882,"numValue":-0.163185718913846,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182883,"numValue":0.0480489391494039,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12882 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,882 | train | mutant | 3,788,290 | 225 | 3,792,235 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242G | Q242G | 1 | 1 | 0 | 0 | 242 | Q | G | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,520 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.093175 | 0.09641 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675722,"numValue":-0.0931748113304425,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675723,"numValue":0.0964102857067933,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12883 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,883 | train | mutant | 3,788,290 | 225 | 3,792,235 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242G | Q242G | 1 | 1 | 0 | 0 | 242 | Q | G | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,101 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.008377 | 0.04743 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182884,"numValue":-0.00837702657274699,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182885,"numValue":0.0474301467837985,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12884 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,884 | train | mutant | 3,788,291 | 225 | 3,792,236 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242H | Q242H | 1 | 1 | 0 | 0 | 242 | Q | H | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,521 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079472 | 0.095157 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675724,"numValue":-0.0794724379243274,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675725,"numValue":0.0951571169362393,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12885 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,885 | train | mutant | 3,788,291 | 225 | 3,792,236 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242H | Q242H | 1 | 1 | 0 | 0 | 242 | Q | H | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,102 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011184 | 0.046801 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182886,"numValue":0.011184221647657,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182887,"numValue":0.0468006842124236,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12886 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,886 | train | mutant | 3,788,292 | 225 | 3,792,237 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242I | Q242I | 1 | 1 | 0 | 0 | 242 | Q | I | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,522 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.038168 | 0.073113 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675726,"numValue":-0.0381683148265668,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675727,"numValue":0.0731131170098507,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12887 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,887 | train | mutant | 3,788,292 | 225 | 3,792,237 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242I | Q242I | 1 | 1 | 0 | 0 | 242 | Q | I | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,103 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020383 | 0.049178 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182888,"numValue":-0.020383196211442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182889,"numValue":0.0491779360371134,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12889 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,889 | train | mutant | 3,788,293 | 225 | 3,792,238 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242K | Q242K | 1 | 1 | 0 | 0 | 242 | Q | K | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,104 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.024665 | 0.061446 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182890,"numValue":0.0246648052528509,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182891,"numValue":0.0614456410922403,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12890 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,890 | train | mutant | 3,788,294 | 225 | 3,792,239 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242L | Q242L | 1 | 1 | 0 | 0 | 242 | Q | L | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,524 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.065275 | 0.081777 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675730,"numValue":0.0652752876286488,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675731,"numValue":0.0817770081478442,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12892 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,892 | train | mutant | 3,788,295 | 225 | 3,792,240 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242M | Q242M | 1 | 1 | 0 | 0 | 242 | Q | M | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,525 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.059012 | 0.047059 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675732,"numValue":-0.059012079183108,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675733,"numValue":0.0470585910464342,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12893 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,893 | train | mutant | 3,788,295 | 225 | 3,792,240 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242M | Q242M | 1 | 1 | 0 | 0 | 242 | Q | M | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,106 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033885 | 0.056768 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182894,"numValue":-0.0338852634524132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182895,"numValue":0.0567675396172069,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12894 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,894 | train | mutant | 3,788,296 | 225 | 3,792,241 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242N | Q242N | 1 | 1 | 0 | 0 | 242 | Q | N | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,526 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.161295 | 0.103657 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675734,"numValue":-0.161294731865735,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675735,"numValue":0.103657025429544,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12895 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,895 | train | mutant | 3,788,296 | 225 | 3,792,241 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242N | Q242N | 1 | 1 | 0 | 0 | 242 | Q | N | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,107 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.038891 | 0.052651 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182896,"numValue":0.0388909505885408,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182897,"numValue":0.0526510999504154,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12896 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,896 | train | mutant | 3,788,297 | 225 | 3,792,242 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242P | Q242P | 1 | 1 | 0 | 0 | 242 | Q | P | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,527 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.137037 | 0.113482 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675736,"numValue":-0.137037338703935,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675737,"numValue":0.113482109400741,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12898 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,898 | train | mutant | 3,788,298 | 225 | 3,792,243 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242R | Q242R | 1 | 1 | 0 | 0 | 242 | Q | R | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,528 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.067084 | 0.069359 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675738,"numValue":-0.0670837362522525,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675739,"numValue":0.0693585281745299,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12899 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,899 | train | mutant | 3,788,298 | 225 | 3,792,243 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242R | Q242R | 1 | 1 | 0 | 0 | 242 | Q | R | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,709 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.059814 | 0.047874 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184100,"numValue":-0.059814420455273,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184101,"numValue":0.0478735292417327,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12900 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,900 | train | mutant | 3,788,299 | 225 | 3,792,244 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242S | Q242S | 1 | 1 | 0 | 0 | 242 | Q | S | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,529 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.181121 | 0.08947 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675740,"numValue":-0.181120758664559,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675741,"numValue":0.0894702074605849,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12901 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,901 | train | mutant | 3,788,299 | 225 | 3,792,244 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242S | Q242S | 1 | 1 | 0 | 0 | 242 | Q | S | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,710 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.068735 | 0.044411 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184102,"numValue":0.0687349034441663,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184103,"numValue":0.0444111787584386,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12902 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,902 | train | mutant | 3,788,300 | 225 | 3,792,245 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242T | Q242T | 1 | 1 | 0 | 0 | 242 | Q | T | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,530 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.147103 | 0.086698 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675742,"numValue":-0.147102591319409,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675743,"numValue":0.0866976060174535,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12903 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,903 | train | mutant | 3,788,300 | 225 | 3,792,245 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242T | Q242T | 1 | 1 | 0 | 0 | 242 | Q | T | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,711 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.062397 | 0.047416 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184104,"numValue":0.0623972308898416,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184105,"numValue":0.0474161665067389,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12904 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,904 | train | mutant | 3,788,301 | 225 | 3,792,246 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242V | Q242V | 1 | 1 | 0 | 0 | 242 | Q | V | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,531 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.017493 | 0.071474 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675744,"numValue":0.017493352691641,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675745,"numValue":0.0714744878615495,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12906 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,906 | train | mutant | 3,788,302 | 225 | 3,792,247 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242W | Q242W | 1 | 1 | 0 | 0 | 242 | Q | W | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,532 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.293355 | 0.056392 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675746,"numValue":0.293354538001444,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675747,"numValue":0.0563915594167515,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12907 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,907 | train | mutant | 3,788,302 | 225 | 3,792,247 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242W | Q242W | 1 | 1 | 0 | 0 | 242 | Q | W | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,713 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.276343 | 0.066557 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184108,"numValue":-0.27634321131412,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184109,"numValue":0.0665568128800348,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12908 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,908 | train | mutant | 3,788,303 | 225 | 3,792,248 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242Y | Q242Y | 1 | 1 | 0 | 0 | 242 | Q | Y | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,841,533 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.101128 | 0.045443 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9675748,"numValue":0.101127619635577,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9675749,"numValue":0.0454425260252709,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12909 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,909 | train | mutant | 3,788,303 | 225 | 3,792,248 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | Q242Y | Q242Y | 1 | 1 | 0 | 0 | 242 | Q | Y | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,714 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.182399 | 0.048918 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184110,"numValue":-0.182399250510742,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184111,"numValue":0.048918262535782,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12910 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,910 | train | mutant | 4,906,049 | 225 | 4,912,637 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delQ242 | delQ242 | 1 | 0 | 1 | 0 | 242 | Q | - | 2 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,095 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.24044 | 0.089026 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182872,"numValue":-1.24043963587099,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182873,"numValue":0.0890255608837227,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16906,"numValue":2.0,"position":242,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12911 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,911 | train | mutant | 3,789,594 | 225 | 3,793,539 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243A | D243A | 1 | 1 | 0 | 0 | 243 | D | A | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,826 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.088306 | 0.083764 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678334,"numValue":-0.0883061946741292,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678335,"numValue":0.0837643482591674,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12912 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,912 | train | mutant | 3,789,594 | 225 | 3,793,539 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243A | D243A | 1 | 1 | 0 | 0 | 243 | D | A | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,110 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.015733 | 0.046735 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182902,"numValue":0.0157331826009621,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182903,"numValue":0.0467345464418379,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12913 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,913 | train | mutant | 3,789,595 | 225 | 3,793,540 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243C | D243C | 1 | 1 | 0 | 0 | 243 | D | C | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,827 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015577 | 0.084497 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678336,"numValue":-0.0155767961076147,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678337,"numValue":0.084497029728386,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12914 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,914 | train | mutant | 3,789,595 | 225 | 3,793,540 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243C | D243C | 1 | 1 | 0 | 0 | 243 | D | C | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,111 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.086884 | 0.044903 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12182904,"numValue":-0.0868838015347614,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12182905,"numValue":0.0449027323019271,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12915 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,915 | train | mutant | 3,789,596 | 225 | 3,793,541 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243E | D243E | 1 | 1 | 0 | 0 | 243 | D | E | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,828 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.160239 | 0.11583 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678338,"numValue":-0.160239207384554,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678339,"numValue":0.115830277496881,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12916 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,916 | train | mutant | 3,789,596 | 225 | 3,793,541 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243E | D243E | 1 | 1 | 0 | 0 | 243 | D | E | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,692 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.031492 | 0.067363 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184066,"numValue":0.0314918272887713,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184067,"numValue":0.0673634915758666,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12917 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,917 | train | mutant | 3,789,597 | 225 | 3,793,542 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243F | D243F | 1 | 1 | 0 | 0 | 243 | D | F | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,829 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.167835 | 0.080161 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678340,"numValue":0.167834649068082,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678341,"numValue":0.0801609071177009,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12918 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,918 | train | mutant | 3,789,597 | 225 | 3,793,542 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243F | D243F | 1 | 1 | 0 | 0 | 243 | D | F | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,693 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.194019 | 0.044927 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184068,"numValue":-0.194018714705445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184069,"numValue":0.0449270804224747,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12919 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,919 | train | mutant | 3,789,598 | 225 | 3,793,543 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243G | D243G | 1 | 1 | 0 | 0 | 243 | D | G | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,830 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.117661 | 0.095003 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678342,"numValue":-0.117660940285347,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678343,"numValue":0.0950031785464294,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12920 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,920 | train | mutant | 3,789,598 | 225 | 3,793,543 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243G | D243G | 1 | 1 | 0 | 0 | 243 | D | G | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,694 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033238 | 0.047968 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184070,"numValue":-0.0332383673084501,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184071,"numValue":0.047967707135459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12921 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,921 | train | mutant | 3,789,599 | 225 | 3,793,544 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243H | D243H | 1 | 1 | 0 | 0 | 243 | D | H | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,831 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.018291 | 0.069905 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678344,"numValue":0.0182910978867282,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678345,"numValue":0.069904916060063,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12922 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,922 | train | mutant | 3,789,599 | 225 | 3,793,544 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243H | D243H | 1 | 1 | 0 | 0 | 243 | D | H | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,695 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.019412 | 0.04446 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184072,"numValue":-0.0194116584601763,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184073,"numValue":0.0444603603705646,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12923 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,923 | train | mutant | 3,789,600 | 225 | 3,793,545 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243I | D243I | 1 | 1 | 0 | 0 | 243 | D | I | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,832 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.136478 | 0.098457 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678346,"numValue":0.136478389310759,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678347,"numValue":0.0984567773195693,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12924 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,924 | train | mutant | 3,789,600 | 225 | 3,793,545 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243I | D243I | 1 | 1 | 0 | 0 | 243 | D | I | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,696 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.126274 | 0.046283 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184074,"numValue":-0.12627444557768,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184075,"numValue":0.0462829763316018,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12926 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,926 | train | mutant | 3,789,601 | 225 | 3,793,546 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243K | D243K | 1 | 1 | 0 | 0 | 243 | D | K | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,697 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.033809 | 0.06959 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184076,"numValue":0.0338088771918714,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184077,"numValue":0.0695899839757141,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12927 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,927 | train | mutant | 3,789,602 | 225 | 3,793,547 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243L | D243L | 1 | 1 | 0 | 0 | 243 | D | L | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,834 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.090768 | 0.096986 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678350,"numValue":0.0907682130377322,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678351,"numValue":0.096985517910645,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12928 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,928 | train | mutant | 3,789,602 | 225 | 3,793,547 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243L | D243L | 1 | 1 | 0 | 0 | 243 | D | L | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,698 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.118489 | 0.043185 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184078,"numValue":-0.118489412524131,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184079,"numValue":0.0431847018626149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12929 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,929 | train | mutant | 3,789,603 | 225 | 3,793,548 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243M | D243M | 1 | 1 | 0 | 0 | 243 | D | M | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,835 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.066744 | 0.08715 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678352,"numValue":0.0667438598674351,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678353,"numValue":0.0871503514250274,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12930 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,930 | train | mutant | 3,789,603 | 225 | 3,793,548 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243M | D243M | 1 | 1 | 0 | 0 | 243 | D | M | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,699 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015641 | 0.054529 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184080,"numValue":-0.0156408825361406,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184081,"numValue":0.0545294460540395,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12931 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,931 | train | mutant | 3,789,604 | 225 | 3,793,549 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243N | D243N | 1 | 1 | 0 | 0 | 243 | D | N | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,836 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.070164 | 0.114356 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678354,"numValue":-0.0701642369806162,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678355,"numValue":0.114356092358326,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12932 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,932 | train | mutant | 3,789,604 | 225 | 3,793,549 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243N | D243N | 1 | 1 | 0 | 0 | 243 | D | N | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,700 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.033681 | 0.047415 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184082,"numValue":0.0336807710674213,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184083,"numValue":0.0474146069539195,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12933 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,933 | train | mutant | 3,789,605 | 225 | 3,793,550 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243P | D243P | 1 | 1 | 0 | 0 | 243 | D | P | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,837 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.413446 | 0.04441 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678356,"numValue":0.413446219475359,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678357,"numValue":0.04440973108748,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12934 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,934 | train | mutant | 3,789,605 | 225 | 3,793,550 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243P | D243P | 1 | 1 | 0 | 0 | 243 | D | P | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,701 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.411729 | 0.048778 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184084,"numValue":-0.411729105532047,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184085,"numValue":0.0487784358944799,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12935 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,935 | train | mutant | 3,789,606 | 225 | 3,793,551 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243Q | D243Q | 1 | 1 | 0 | 0 | 243 | D | Q | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,838 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.06274 | 0.073082 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678358,"numValue":-0.0627398503305198,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678359,"numValue":0.0730816204050935,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12936 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,936 | train | mutant | 3,789,606 | 225 | 3,793,551 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243Q | D243Q | 1 | 1 | 0 | 0 | 243 | D | Q | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,702 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.031524 | 0.054811 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184086,"numValue":-0.0315244505875441,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184087,"numValue":0.0548113113554387,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12937 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,937 | train | mutant | 3,789,607 | 225 | 3,793,552 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243R | D243R | 1 | 1 | 0 | 0 | 243 | D | R | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,839 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.013259 | 0.09785 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678360,"numValue":-0.0132594224411209,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678361,"numValue":0.0978500597637666,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12938 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,938 | train | mutant | 3,789,607 | 225 | 3,793,552 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243R | D243R | 1 | 1 | 0 | 0 | 243 | D | R | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,703 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.109684 | 0.045489 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184088,"numValue":-0.109684304616265,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184089,"numValue":0.0454894663088114,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12939 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,939 | train | mutant | 3,789,608 | 225 | 3,793,553 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243S | D243S | 1 | 1 | 0 | 0 | 243 | D | S | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,840 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.049632 | 0.061408 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678362,"numValue":-0.0496322575033133,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678363,"numValue":0.0614081504755502,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12940 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,940 | train | mutant | 3,789,608 | 225 | 3,793,553 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243S | D243S | 1 | 1 | 0 | 0 | 243 | D | S | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,704 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.019081 | 0.042818 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184090,"numValue":0.0190806513311622,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184091,"numValue":0.0428176977083203,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12942 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,942 | train | mutant | 3,789,609 | 225 | 3,793,554 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243T | D243T | 1 | 1 | 0 | 0 | 243 | D | T | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,705 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.017603 | 0.046003 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184092,"numValue":0.0176030546038073,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184093,"numValue":0.0460034185318232,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12943 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,943 | train | mutant | 3,789,610 | 225 | 3,793,555 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243V | D243V | 1 | 1 | 0 | 0 | 243 | D | V | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,842 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.084044 | 0.074422 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678366,"numValue":0.084043991747849,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678367,"numValue":0.0744221334579358,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12944 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,944 | train | mutant | 3,789,610 | 225 | 3,793,555 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243V | D243V | 1 | 1 | 0 | 0 | 243 | D | V | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,706 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.144951 | 0.047012 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184094,"numValue":-0.144950886280141,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184095,"numValue":0.0470123218955371,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12945 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,945 | train | mutant | 3,789,611 | 225 | 3,793,556 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243W | D243W | 1 | 1 | 0 | 0 | 243 | D | W | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,843 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.227675 | 0.082909 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678368,"numValue":0.227674878528826,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678369,"numValue":0.0829090112015767,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12947 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,947 | train | mutant | 3,789,612 | 225 | 3,793,557 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243Y | D243Y | 1 | 1 | 0 | 0 | 243 | D | Y | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,842,844 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.139337 | 0.103349 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9678370,"numValue":0.139337119733102,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9678371,"numValue":0.103349126144312,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:12948 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 12,948 | train | mutant | 3,789,612 | 225 | 3,793,557 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | D243Y | D243Y | 1 | 1 | 0 | 0 | 243 | D | Y | 3 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,708 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.106089 | 0.045261 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12184098,"numValue":-0.106089376229518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12184099,"numValue":0.0452611668726172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16907,"numValue":3.0,"position":243,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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