row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:13284 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,284 | train | mutant | 3,801,460 | 225 | 3,805,405 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252P | K252P | 1 | 1 | 0 | 0 | 252 | K | P | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,712 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.245268 | 0.068147 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702106,"numValue":0.245267774670035,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702107,"numValue":0.0681469835343785,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13285 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,285 | train | mutant | 3,801,460 | 225 | 3,805,405 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252P | K252P | 1 | 1 | 0 | 0 | 252 | K | P | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,609 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.177075 | 0.057334 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183900,"numValue":-0.177075287289024,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183901,"numValue":0.0573341506185797,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13286 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,286 | train | mutant | 3,801,461 | 225 | 3,805,406 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252Q | K252Q | 1 | 1 | 0 | 0 | 252 | K | Q | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,713 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.017682 | 0.065792 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702108,"numValue":0.0176824122151085,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702109,"numValue":0.065791883709575,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13287 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,287 | train | mutant | 3,801,461 | 225 | 3,805,406 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252Q | K252Q | 1 | 1 | 0 | 0 | 252 | K | Q | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,610 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.040388 | 0.060872 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183902,"numValue":0.040387643881031,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183903,"numValue":0.0608719166203545,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13288 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,288 | train | mutant | 3,801,462 | 225 | 3,805,407 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252R | K252R | 1 | 1 | 0 | 0 | 252 | K | R | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,714 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.042205 | 0.083108 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702110,"numValue":-0.0422045107652638,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702111,"numValue":0.0831083276579617,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13289 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,289 | train | mutant | 3,801,462 | 225 | 3,805,407 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252R | K252R | 1 | 1 | 0 | 0 | 252 | K | R | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,611 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.021775 | 0.045336 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183904,"numValue":-0.0217748583956873,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183905,"numValue":0.0453362084166973,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13290 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,290 | train | mutant | 3,801,463 | 225 | 3,805,408 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252S | K252S | 1 | 1 | 0 | 0 | 252 | K | S | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,715 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.009729 | 0.095127 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702112,"numValue":-0.00972883309274421,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702113,"numValue":0.0951267748694057,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13291 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,291 | train | mutant | 3,801,463 | 225 | 3,805,408 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252S | K252S | 1 | 1 | 0 | 0 | 252 | K | S | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,612 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.056705 | 0.052897 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183906,"numValue":-0.056704863099052,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183907,"numValue":0.0528968807006106,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13292 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,292 | train | mutant | 3,801,464 | 225 | 3,805,409 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252T | K252T | 1 | 1 | 0 | 0 | 252 | K | T | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,716 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.063391 | 0.0944 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702114,"numValue":-0.0633910097194156,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702115,"numValue":0.0943997918212835,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13293 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,293 | train | mutant | 3,801,464 | 225 | 3,805,409 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252T | K252T | 1 | 1 | 0 | 0 | 252 | K | T | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,613 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.094266 | 0.060991 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183908,"numValue":-0.0942662153400376,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183909,"numValue":0.060990928005659,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13294 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,294 | train | mutant | 3,801,465 | 225 | 3,805,410 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252V | K252V | 1 | 1 | 0 | 0 | 252 | K | V | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,717 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020207 | 0.075043 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702116,"numValue":-0.0202073731505976,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702117,"numValue":0.0750428832631604,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13295 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,295 | train | mutant | 3,801,465 | 225 | 3,805,410 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252V | K252V | 1 | 1 | 0 | 0 | 252 | K | V | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,614 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079996 | 0.045705 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183910,"numValue":-0.0799963070425789,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183911,"numValue":0.0457045732012578,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13296 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,296 | train | mutant | 3,801,466 | 225 | 3,805,411 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252W | K252W | 1 | 1 | 0 | 0 | 252 | K | W | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,718 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.193914 | 0.083344 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702118,"numValue":0.19391373653175,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702119,"numValue":0.0833442922538155,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13297 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,297 | train | mutant | 3,801,466 | 225 | 3,805,411 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252W | K252W | 1 | 1 | 0 | 0 | 252 | K | W | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,615 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.203592 | 0.055074 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183912,"numValue":-0.203591663669799,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183913,"numValue":0.0550735708499654,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13298 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,298 | train | mutant | 3,801,467 | 225 | 3,805,412 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252Y | K252Y | 1 | 1 | 0 | 0 | 252 | K | Y | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,854,719 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.1594 | 0.081328 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9702120,"numValue":0.159399781795033,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9702121,"numValue":0.0813283137505284,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13299 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,299 | train | mutant | 3,801,467 | 225 | 3,805,412 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K252Y | K252Y | 1 | 1 | 0 | 0 | 252 | K | Y | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,616 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.219953 | 0.096883 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183914,"numValue":-0.219952645849589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183915,"numValue":0.0968828426087001,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13300 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,300 | train | mutant | 4,906,058 | 225 | 4,912,646 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delK252 | delK252 | 1 | 0 | 1 | 0 | 252 | K | - | 4 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,197 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.239855 | 0.098536 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183076,"numValue":-1.2398547319516,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183077,"numValue":0.0985362073043224,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16916,"numValue":4.0,"position":252,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13301 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,301 | train | mutant | 3,802,758 | 225 | 3,806,703 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253A | N253A | 1 | 1 | 0 | 0 | 253 | N | A | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,012 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.006585 | 0.10206 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704706,"numValue":0.00658546428607188,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704707,"numValue":0.102059667073528,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13302 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,302 | train | mutant | 3,802,758 | 225 | 3,806,703 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253A | N253A | 1 | 1 | 0 | 0 | 253 | N | A | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,207 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.083579 | 0.047381 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183096,"numValue":0.0835785043859022,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183097,"numValue":0.0473810049561833,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13303 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,303 | train | mutant | 3,802,759 | 225 | 3,806,704 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253C | N253C | 1 | 1 | 0 | 0 | 253 | N | C | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,013 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.030046 | 0.06684 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704708,"numValue":0.0300462226797083,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704709,"numValue":0.0668404201980608,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13304 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,304 | train | mutant | 3,802,759 | 225 | 3,806,704 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253C | N253C | 1 | 1 | 0 | 0 | 253 | N | C | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,208 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.066142 | 0.051713 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183098,"numValue":0.066141749036816,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183099,"numValue":0.0517126708689534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13305 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,305 | train | mutant | 3,802,760 | 225 | 3,806,705 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253D | N253D | 1 | 1 | 0 | 0 | 253 | N | D | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,014 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.152615 | 0.063974 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704710,"numValue":0.152615082297838,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704711,"numValue":0.06397378130347,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13306 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,306 | train | mutant | 3,802,760 | 225 | 3,806,705 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253D | N253D | 1 | 1 | 0 | 0 | 253 | N | D | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,209 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.011082 | 0.064689 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183100,"numValue":-0.0110823733002679,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183101,"numValue":0.0646886913956602,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13307 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,307 | train | mutant | 3,802,761 | 225 | 3,806,706 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253E | N253E | 1 | 1 | 0 | 0 | 253 | N | E | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,015 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.154411 | 0.058468 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704712,"numValue":0.15441064758354,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704713,"numValue":0.0584678405835731,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13308 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,308 | train | mutant | 3,802,761 | 225 | 3,806,706 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253E | N253E | 1 | 1 | 0 | 0 | 253 | N | E | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,210 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079946 | 0.050471 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183102,"numValue":-0.0799461785590982,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183103,"numValue":0.0504711554280855,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13309 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,309 | train | mutant | 3,802,762 | 225 | 3,806,707 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253F | N253F | 1 | 1 | 0 | 0 | 253 | N | F | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,016 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.150083 | 0.094872 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704714,"numValue":0.150083054600009,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704715,"numValue":0.0948721171117718,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13310 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,310 | train | mutant | 3,802,762 | 225 | 3,806,707 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253F | N253F | 1 | 1 | 0 | 0 | 253 | N | F | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,211 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.316489 | 0.07214 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183104,"numValue":0.316488965370102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183105,"numValue":0.0721401790684117,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13311 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,311 | train | mutant | 3,802,763 | 225 | 3,806,708 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253G | N253G | 1 | 1 | 0 | 0 | 253 | N | G | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,017 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.080174 | 0.096481 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704716,"numValue":0.0801742304403277,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704717,"numValue":0.0964808408021228,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13312 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,312 | train | mutant | 3,802,763 | 225 | 3,806,708 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253G | N253G | 1 | 1 | 0 | 0 | 253 | N | G | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,212 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.070782 | 0.042147 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183106,"numValue":0.0707822143647284,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183107,"numValue":0.04214705021147,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13313 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,313 | train | mutant | 3,802,764 | 225 | 3,806,709 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253H | N253H | 1 | 1 | 0 | 0 | 253 | N | H | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,018 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.020537 | 0.08456 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704718,"numValue":0.0205372412895161,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704719,"numValue":0.0845601354659631,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13314 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,314 | train | mutant | 3,802,764 | 225 | 3,806,709 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253H | N253H | 1 | 1 | 0 | 0 | 253 | N | H | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,213 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.146287 | 0.079691 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183108,"numValue":-0.146286850149408,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183109,"numValue":0.079690602862369,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13315 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,315 | train | mutant | 3,802,765 | 225 | 3,806,710 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253I | N253I | 1 | 1 | 0 | 0 | 253 | N | I | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,019 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.293412 | 0.12403 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704720,"numValue":0.293412309908847,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704721,"numValue":0.124030399978276,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13316 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,316 | train | mutant | 3,802,765 | 225 | 3,806,710 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253I | N253I | 1 | 1 | 0 | 0 | 253 | N | I | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,214 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.084848 | 0.084564 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183110,"numValue":0.0848476302771952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183111,"numValue":0.0845642054229765,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13317 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,317 | train | mutant | 3,802,766 | 225 | 3,806,711 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253K | N253K | 1 | 1 | 0 | 0 | 253 | N | K | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,020 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.006959 | 0.132192 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704722,"numValue":0.00695928341067391,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704723,"numValue":0.132191812806093,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13318 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,318 | train | mutant | 3,802,766 | 225 | 3,806,711 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253K | N253K | 1 | 1 | 0 | 0 | 253 | N | K | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,215 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.040988 | 0.075647 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183112,"numValue":-0.0409875943023695,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183113,"numValue":0.0756469608932542,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13319 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,319 | train | mutant | 3,802,767 | 225 | 3,806,712 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253L | N253L | 1 | 1 | 0 | 0 | 253 | N | L | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,021 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.000326 | 0.111454 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704724,"numValue":0.000325770924637713,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704725,"numValue":0.111453999247012,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13320 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,320 | train | mutant | 3,802,767 | 225 | 3,806,712 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253L | N253L | 1 | 1 | 0 | 0 | 253 | N | L | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,216 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.221379 | 0.048356 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183114,"numValue":0.221379318403249,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183115,"numValue":0.0483555185888491,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13321 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,321 | train | mutant | 3,802,768 | 225 | 3,806,713 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253M | N253M | 1 | 1 | 0 | 0 | 253 | N | M | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,022 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.096328 | 0.116558 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704726,"numValue":0.0963281334693191,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704727,"numValue":0.116557737663989,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13322 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,322 | train | mutant | 3,802,768 | 225 | 3,806,713 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253M | N253M | 1 | 1 | 0 | 0 | 253 | N | M | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,217 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.182097 | 0.071886 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183116,"numValue":0.182096888229431,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183117,"numValue":0.0718859640019483,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13323 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,323 | train | mutant | 3,802,769 | 225 | 3,806,714 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253P | N253P | 1 | 1 | 0 | 0 | 253 | N | P | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,023 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.887752 | 0.116044 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704728,"numValue":0.887752116395733,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704729,"numValue":0.116044193344124,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13325 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,325 | train | mutant | 3,802,770 | 225 | 3,806,715 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253Q | N253Q | 1 | 1 | 0 | 0 | 253 | N | Q | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,024 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.072297 | 0.083724 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704730,"numValue":0.0722971197629892,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704731,"numValue":0.0837236356060729,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13326 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,326 | train | mutant | 3,802,770 | 225 | 3,806,715 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253Q | N253Q | 1 | 1 | 0 | 0 | 253 | N | Q | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,599 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.026826 | 0.058561 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183880,"numValue":-0.0268258998740116,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183881,"numValue":0.0585612163251618,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13327 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,327 | train | mutant | 3,802,771 | 225 | 3,806,716 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253R | N253R | 1 | 1 | 0 | 0 | 253 | N | R | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,025 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.085664 | 0.091335 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704732,"numValue":0.0856643620926922,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704733,"numValue":0.0913354906328298,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13328 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,328 | train | mutant | 3,802,771 | 225 | 3,806,716 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253R | N253R | 1 | 1 | 0 | 0 | 253 | N | R | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,600 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.024813 | 0.043224 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183882,"numValue":0.0248128036326504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183883,"numValue":0.0432242556231517,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13329 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,329 | train | mutant | 3,802,772 | 225 | 3,806,717 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253S | N253S | 1 | 1 | 0 | 0 | 253 | N | S | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,026 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.057337 | 0.085535 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704734,"numValue":-0.0573370652110048,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704735,"numValue":0.085534966073363,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13330 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,330 | train | mutant | 3,802,772 | 225 | 3,806,717 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253S | N253S | 1 | 1 | 0 | 0 | 253 | N | S | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,601 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.076299 | 0.049254 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183884,"numValue":-0.0762987346182289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183885,"numValue":0.0492544416511872,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13331 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,331 | train | mutant | 3,802,773 | 225 | 3,806,718 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253T | N253T | 1 | 1 | 0 | 0 | 253 | N | T | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,027 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.180886 | 0.143658 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704736,"numValue":-0.180886486490769,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704737,"numValue":0.143657758482356,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13332 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,332 | train | mutant | 3,802,773 | 225 | 3,806,718 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253T | N253T | 1 | 1 | 0 | 0 | 253 | N | T | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,602 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.104773 | 0.055177 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183886,"numValue":-0.1047733046156,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183887,"numValue":0.0551766366033818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13333 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,333 | train | mutant | 3,802,774 | 225 | 3,806,719 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253V | N253V | 1 | 1 | 0 | 0 | 253 | N | V | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,028 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.287077 | 0.059713 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704738,"numValue":0.287077430089595,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704739,"numValue":0.059713383327316,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13334 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,334 | train | mutant | 3,802,774 | 225 | 3,806,719 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253V | N253V | 1 | 1 | 0 | 0 | 253 | N | V | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,603 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.014743 | 0.045326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183888,"numValue":-0.0147425482845608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183889,"numValue":0.045326397556359,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13335 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,335 | train | mutant | 3,802,775 | 225 | 3,806,720 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253W | N253W | 1 | 1 | 0 | 0 | 253 | N | W | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,029 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.302477 | 0.156761 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704740,"numValue":0.30247689547372,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704741,"numValue":0.156760514853426,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13336 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,336 | train | mutant | 3,802,775 | 225 | 3,806,720 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253W | N253W | 1 | 1 | 0 | 0 | 253 | N | W | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,604 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.15451 | 0.048646 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183890,"numValue":0.154509512820644,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183891,"numValue":0.0486464945431983,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13337 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,337 | train | mutant | 3,802,776 | 225 | 3,806,721 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253Y | N253Y | 1 | 1 | 0 | 0 | 253 | N | Y | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,856,030 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.127785 | 0.074461 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9704742,"numValue":0.12778479751589,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9704743,"numValue":0.0744607868474824,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13338 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,338 | train | mutant | 3,802,776 | 225 | 3,806,721 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | N253Y | N253Y | 1 | 1 | 0 | 0 | 253 | N | Y | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,605 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.296257 | 0.053855 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183892,"numValue":0.296256950299315,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183893,"numValue":0.0538552099943242,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13339 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,339 | train | mutant | 4,906,059 | 225 | 4,912,647 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delN253 | delN253 | 1 | 0 | 1 | 0 | 253 | N | - | 5 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,206 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.218503 | 0.094349 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183094,"numValue":-1.21850344730597,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183095,"numValue":0.0943493649673982,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16917,"numValue":5.0,"position":253,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13340 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,340 | train | mutant | 3,804,064 | 225 | 3,808,009 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254A | K254A | 1 | 1 | 0 | 0 | 254 | K | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,323 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.027168 | 0.066466 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707328,"numValue":0.0271683028468292,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707329,"numValue":0.0664662418838825,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13341 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,341 | train | mutant | 3,804,064 | 225 | 3,808,009 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254A | K254A | 1 | 1 | 0 | 0 | 254 | K | A | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,219 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.014182 | 0.049997 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183120,"numValue":-0.0141823823739212,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183121,"numValue":0.0499967728794147,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13343 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,343 | train | mutant | 3,804,065 | 225 | 3,808,010 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254C | K254C | 1 | 1 | 0 | 0 | 254 | K | C | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,220 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.00117 | 0.063361 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183122,"numValue":0.00117046030475986,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183123,"numValue":0.0633608753941844,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13344 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,344 | train | mutant | 3,804,066 | 225 | 3,808,011 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254D | K254D | 1 | 1 | 0 | 0 | 254 | K | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,325 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.180496 | 0.133881 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707332,"numValue":0.180496396708521,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707333,"numValue":0.133881459927473,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13345 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,345 | train | mutant | 3,804,066 | 225 | 3,808,011 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254D | K254D | 1 | 1 | 0 | 0 | 254 | K | D | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,221 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.534747 | 0.078116 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183124,"numValue":-0.53474679106392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183125,"numValue":0.0781159478427133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13346 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,346 | train | mutant | 3,804,067 | 225 | 3,808,012 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254E | K254E | 1 | 1 | 0 | 0 | 254 | K | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,326 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.036421 | 0.100798 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707334,"numValue":0.0364207236298469,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707335,"numValue":0.10079795179661,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13347 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,347 | train | mutant | 3,804,067 | 225 | 3,808,012 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254E | K254E | 1 | 1 | 0 | 0 | 254 | K | E | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,222 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.182457 | 0.053496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183126,"numValue":-0.182456540206149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183127,"numValue":0.0534964889751571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13348 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,348 | train | mutant | 3,804,068 | 225 | 3,808,013 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254F | K254F | 1 | 1 | 0 | 0 | 254 | K | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,327 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.322208 | 0.069872 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707336,"numValue":0.322208128632503,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707337,"numValue":0.0698724550898082,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13349 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,349 | train | mutant | 3,804,068 | 225 | 3,808,013 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254F | K254F | 1 | 1 | 0 | 0 | 254 | K | F | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,223 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.358387 | 0.079491 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183128,"numValue":-0.358386829277261,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183129,"numValue":0.0794907493513245,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13350 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,350 | train | mutant | 3,804,069 | 225 | 3,808,014 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254G | K254G | 1 | 1 | 0 | 0 | 254 | K | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,328 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.071557 | 0.101804 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707338,"numValue":-0.0715572545022461,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707339,"numValue":0.101803755753276,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13351 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,351 | train | mutant | 3,804,069 | 225 | 3,808,014 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254G | K254G | 1 | 1 | 0 | 0 | 254 | K | G | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,224 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.040567 | 0.042513 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183130,"numValue":0.0405666741791758,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183131,"numValue":0.0425132745893549,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13352 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,352 | train | mutant | 3,804,070 | 225 | 3,808,015 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254H | K254H | 1 | 1 | 0 | 0 | 254 | K | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,329 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.049063 | 0.104187 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707340,"numValue":-0.0490634765332977,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707341,"numValue":0.104186953835342,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13353 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,353 | train | mutant | 3,804,070 | 225 | 3,808,015 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254H | K254H | 1 | 1 | 0 | 0 | 254 | K | H | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,225 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.001932 | 0.086568 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183132,"numValue":0.00193193583953563,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183133,"numValue":0.0865684695029625,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13354 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,354 | train | mutant | 3,804,071 | 225 | 3,808,016 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254I | K254I | 1 | 1 | 0 | 0 | 254 | K | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,330 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.587252 | 0.108065 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707342,"numValue":0.587251663815742,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707343,"numValue":0.108065138993639,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13355 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,355 | train | mutant | 3,804,071 | 225 | 3,808,016 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254I | K254I | 1 | 1 | 0 | 0 | 254 | K | I | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,226 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.752261 | 0.133026 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183134,"numValue":-0.752261044252777,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183135,"numValue":0.133025797474251,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13356 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,356 | train | mutant | 3,804,072 | 225 | 3,808,017 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254L | K254L | 1 | 1 | 0 | 0 | 254 | K | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,331 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.147878 | 0.054999 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707344,"numValue":0.147878157233333,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707345,"numValue":0.0549985689018567,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13357 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,357 | train | mutant | 3,804,072 | 225 | 3,808,017 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254L | K254L | 1 | 1 | 0 | 0 | 254 | K | L | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,587 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.317749 | 0.051188 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183856,"numValue":-0.317748542978827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183857,"numValue":0.0511882394058234,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13358 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,358 | train | mutant | 3,804,073 | 225 | 3,808,018 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254M | K254M | 1 | 1 | 0 | 0 | 254 | K | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,332 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.007682 | 0.067481 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707346,"numValue":-0.00768194346821036,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707347,"numValue":0.0674805023244618,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13359 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,359 | train | mutant | 3,804,073 | 225 | 3,808,018 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254M | K254M | 1 | 1 | 0 | 0 | 254 | K | M | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,588 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.131419 | 0.05345 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183858,"numValue":-0.131418582811039,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183859,"numValue":0.0534500604511716,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13360 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,360 | train | mutant | 3,804,074 | 225 | 3,808,019 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254N | K254N | 1 | 1 | 0 | 0 | 254 | K | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,333 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.139114 | 0.158676 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707348,"numValue":-0.139113936074613,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707349,"numValue":0.15867559619455,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13361 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,361 | train | mutant | 3,804,074 | 225 | 3,808,019 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254N | K254N | 1 | 1 | 0 | 0 | 254 | K | N | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,589 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.084794 | 0.08247 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183860,"numValue":0.0847935233426448,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183861,"numValue":0.0824702670558753,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13362 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,362 | train | mutant | 3,804,075 | 225 | 3,808,020 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254P | K254P | 1 | 1 | 0 | 0 | 254 | K | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,334 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.654758 | 0.077809 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707350,"numValue":0.654758205133919,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707351,"numValue":0.0778091943875854,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13363 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,363 | train | mutant | 3,804,075 | 225 | 3,808,020 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254P | K254P | 1 | 1 | 0 | 0 | 254 | K | P | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,590 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.600125 | 0.068496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183862,"numValue":-0.600125393616511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183863,"numValue":0.0684961725092667,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13364 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,364 | train | mutant | 3,804,076 | 225 | 3,808,021 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254Q | K254Q | 1 | 1 | 0 | 0 | 254 | K | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,335 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.123414 | 0.092437 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707352,"numValue":-0.123414106284335,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707353,"numValue":0.0924365777266089,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13365 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,365 | train | mutant | 3,804,076 | 225 | 3,808,021 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254Q | K254Q | 1 | 1 | 0 | 0 | 254 | K | Q | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,591 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.05999 | 0.058822 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183864,"numValue":0.0599902679925619,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183865,"numValue":0.0588218287409456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13366 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,366 | train | mutant | 3,804,077 | 225 | 3,808,022 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254R | K254R | 1 | 1 | 0 | 0 | 254 | K | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,336 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.195533 | 0.09469 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707354,"numValue":-0.195533217904897,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707355,"numValue":0.0946899904422489,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13367 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,367 | train | mutant | 3,804,077 | 225 | 3,808,022 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254R | K254R | 1 | 1 | 0 | 0 | 254 | K | R | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,592 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.052362 | 0.04379 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183866,"numValue":0.0523619859111669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183867,"numValue":0.0437897128737143,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13368 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,368 | train | mutant | 3,804,078 | 225 | 3,808,023 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254S | K254S | 1 | 1 | 0 | 0 | 254 | K | S | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,337 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.008959 | 0.086469 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707356,"numValue":-0.00895924354423185,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707357,"numValue":0.086469477875888,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13371 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,371 | train | mutant | 3,804,079 | 225 | 3,808,024 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254T | K254T | 1 | 1 | 0 | 0 | 254 | K | T | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,594 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.251078 | 0.07992 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183870,"numValue":-0.25107845563993,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183871,"numValue":0.0799196025059515,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13373 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,373 | train | mutant | 3,804,080 | 225 | 3,808,025 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254V | K254V | 1 | 1 | 0 | 0 | 254 | K | V | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,595 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.536901 | 0.048599 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183872,"numValue":-0.536901361025326,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183873,"numValue":0.0485986894751426,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13374 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,374 | train | mutant | 3,804,081 | 225 | 3,808,026 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254W | K254W | 1 | 1 | 0 | 0 | 254 | K | W | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,340 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.425794 | 0.055802 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707362,"numValue":0.425794452680236,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707363,"numValue":0.0558015747838763,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13375 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,375 | train | mutant | 3,804,081 | 225 | 3,808,026 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254W | K254W | 1 | 1 | 0 | 0 | 254 | K | W | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,596 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.348088 | 0.048508 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183874,"numValue":-0.34808821083776,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183875,"numValue":0.0485084104634648,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13376 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,376 | train | mutant | 3,804,082 | 225 | 3,808,027 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254Y | K254Y | 1 | 1 | 0 | 0 | 254 | K | Y | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,857,341 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.226468 | 0.028497 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9707364,"numValue":0.226468172595372,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9707365,"numValue":0.0284968597930068,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13377 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,377 | train | mutant | 3,804,082 | 225 | 3,808,027 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | K254Y | K254Y | 1 | 1 | 0 | 0 | 254 | K | Y | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,597 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.365216 | 0.097928 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183876,"numValue":-0.365216238383823,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183877,"numValue":0.0979278225667158,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13378 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,378 | train | mutant | 4,906,060 | 225 | 4,912,648 | 504 | 503 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | delK254 | delK254 | 1 | 0 | 1 | 0 | 254 | K | - | 7 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,218 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.002878 | 0.076022 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183118,"numValue":-1.00287831784469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183119,"numValue":0.0760217628116459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16918,"numValue":7.0,"position":254,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13379 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,379 | train | mutant | 3,805,373 | 225 | 3,809,318 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255A | T255A | 1 | 1 | 0 | 0 | 255 | T | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,634 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.035081 | 0.075796 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709950,"numValue":0.0350811378082415,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709951,"numValue":0.0757955564680031,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13380 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,380 | train | mutant | 3,805,373 | 225 | 3,809,318 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255A | T255A | 1 | 1 | 0 | 0 | 255 | T | A | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,228 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011632 | 0.091096 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183138,"numValue":0.011632195238126,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183139,"numValue":0.0910955489753831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13381 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,381 | train | mutant | 3,805,374 | 225 | 3,809,319 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255C | T255C | 1 | 1 | 0 | 0 | 255 | T | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,635 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.09987 | 0.081247 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709952,"numValue":-0.0998701185346082,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709953,"numValue":0.0812474443329694,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13382 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,382 | train | mutant | 3,805,374 | 225 | 3,809,319 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255C | T255C | 1 | 1 | 0 | 0 | 255 | T | C | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,229 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.284932 | 0.175543 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183140,"numValue":0.284931891483784,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183141,"numValue":0.175543185782012,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13384 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,384 | train | mutant | 3,805,375 | 225 | 3,809,320 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255D | T255D | 1 | 1 | 0 | 0 | 255 | T | D | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,230 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.648923 | 0.146428 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183142,"numValue":-0.648923244352212,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183143,"numValue":0.146428164731411,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13385 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,385 | train | mutant | 3,805,376 | 225 | 3,809,321 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255E | T255E | 1 | 1 | 0 | 0 | 255 | T | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,637 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.068105 | 0.066344 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709956,"numValue":0.0681049655557564,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709957,"numValue":0.0663437809690591,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13386 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,386 | train | mutant | 3,805,376 | 225 | 3,809,321 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255E | T255E | 1 | 1 | 0 | 0 | 255 | T | E | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,231 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183144,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183145,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13388 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,388 | train | mutant | 3,805,377 | 225 | 3,809,322 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255F | T255F | 1 | 1 | 0 | 0 | 255 | T | F | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,232 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.428961 | 0.169715 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183146,"numValue":-0.428960572805927,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183147,"numValue":0.169714993671697,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13389 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,389 | train | mutant | 3,805,378 | 225 | 3,809,323 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255G | T255G | 1 | 1 | 0 | 0 | 255 | T | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 3,858,639 | Domainome DDG | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.314619 | 0.06767 | DOMAINOME_DDG|DOMAINOME_DDG_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":9709960,"numValue":0.314619202323807,"references":[],"strValue":null,"type":"DOMAINOME_DDG"},{"datasets":[],"id":9709961,"numValue":0.0676703034078626,"references":[],"strValue":null,"type":"DOMAINOME_DDG_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||
fireprotdb:13390 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 13,390 | train | mutant | 3,805,378 | 225 | 3,809,323 | 504 | 504 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | 29 | Transcriptional coactivator YAP1 | Homo sapiens | 1 | P46937 | IPR053819|IPR001202|IPR036020|IPR051583 | T255G | T255G | 1 | 1 | 0 | 0 | 255 | T | G | 6 | CONSERVATION | 1K9Q | 347 | null | false | false | null | null | 5,095,233 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.369232 | 0.118133 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12183148,"numValue":-0.369232086893764,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12183149,"numValue":0.118133420722398,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":16919,"numValue":6.0,"position":255,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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