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GO

Dataset card Data Studio Files
xet
 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0002406
2,406
antigen sampling by M cells in mucosal-associated lymphoid tissue
biological_process
The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.
[ "GOC:jal", "PMID:11896763" ]
null
[ "antigen sampling by M cells in MALT" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002404" ]
[]
[]
[]
[ "GO:0002404" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002407
2,407
dendritic cell chemotaxis
biological_process
The movement of a dendritic cell in response to an external stimulus.
[ "CL:0000451", "GOC:add", "ISBN:0781735149", "PMID:15814331", "PMID:16056255" ]
null
[]
[]
[]
[]
[]
[ "GO:0030595", "GO:0036336" ]
[]
[]
[]
[ "GO:0030595", "GO:0036336" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002408
2,408
myeloid dendritic cell chemotaxis
biological_process
The movement of a myeloid dendritic cell in response to an external stimulus.
[ "GOC:add", "ISBN:0781735149", "PMID:15814331", "PMID:16056255" ]
null
[]
[]
[]
[]
[]
[ "GO:0002407", "GO:0097529" ]
[]
[]
[]
[ "GO:0002407", "GO:0097529" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002409
2,409
Langerhans cell chemotaxis
biological_process
The movement of a Langerhans cell in response to an external stimulus.
[ "GOC:add", "PMID:16056255", "PMID:16387601" ]
null
[]
[]
[]
[]
[]
[ "GO:0002408" ]
[]
[]
[]
[ "GO:0002408" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002410
2,410
plasmacytoid dendritic cell chemotaxis
biological_process
The movement of a plasmacytoid dendritic cell in response to an external stimulus.
[ "GOC:add", "PMID:15159375", "PMID:15814331" ]
null
[]
[]
[]
[]
[]
[ "GO:0002407" ]
[]
[]
[]
[ "GO:0002407" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002411
2,411
T cell tolerance induction to tumor cell
biological_process
A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.
[ "GOC:add", "ISBN:0781735149", "PMID:16730260" ]
null
[]
[]
[]
[]
[]
[ "GO:0002413", "GO:0002424", "GO:0002458" ]
[]
[]
[]
[ "GO:0002413", "GO:0002424", "GO:0002458" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002412
2,412
antigen transcytosis by M cells in mucosal-associated lymphoid tissue
biological_process
The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a micr...
[ "GOC:jal", "ISBN:0781735149", "PMID:12843411" ]
null
[ "antigen transcytosis by M cells in MALT", "antigen transport by M cells in MALT", "antigen transport by M cells in mucosal-associated lymphoid tissue" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0045056" ]
[ "part_of GO:0002406" ]
[ "part_of" ]
[ "GO:0002406" ]
[ "GO:0002406", "GO:0045056" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002413
2,413
tolerance induction to tumor cell
biological_process
A process of tolerance induction which leads to immunological tolerance of a tumor.
[ "GOC:add" ]
null
[]
[]
[]
[]
[]
[ "GO:0002418", "GO:0002465" ]
[]
[]
[]
[ "GO:0002418", "GO:0002465" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002414
2,414
immunoglobulin transcytosis in epithelial cells
biological_process
The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other.
[ "GOC:add", "ISBN:0781735149", "ISBN:081533642X", "PMID:16048543" ]
null
[]
[]
[]
[]
[]
[ "GO:0045056" ]
[]
[]
[]
[ "GO:0045056" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002415
2,415
immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
biological_process
The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to...
[ "GOC:add", "ISBN:0781735149", "ISBN:081533642X", "PMID:16048543" ]
null
[ "antibody transcytosis mediated by pIgR", "immunoglobulin transcytosis mediated by pIgR" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002414" ]
[ "part_of GO:0002385" ]
[ "part_of" ]
[ "GO:0002385" ]
[ "GO:0002385", "GO:0002414" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002416
2,416
IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor
biological_process
The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rode...
[ "GOC:add", "ISBN:0781735149", "ISBN:081533642X" ]
null
[ "IgG antibody transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor", "IgG immunoglobulin transcytosis in epithelial cells mediated by neonatal immunoglobulin receptor" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002414" ]
[]
[]
[]
[ "GO:0002414" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002417
2,417
B cell antigen processing and presentation mediated by B cell receptor uptake of antigen
biological_process
B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[ "B lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen", "B-cell antigen processing and presentation mediated by B cell receptor uptake of antigen", "B-lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002450", "GO:0002751" ]
[]
[]
[]
[ "GO:0002450", "GO:0002751" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002419
2,419
T cell mediated cytotoxicity directed against tumor cell target
biological_process
The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
[ "GOC:add", "ISBN:0781735149", "PMID:16730260" ]
Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.
[ "T lymphocyte mediated cytotoxicity directed against tumor cell target", "T-cell mediated cytotoxicity directed against tumor cell target", "T-lymphocyte mediated cytotoxicity directed against tumor cell target" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001913", "GO:0002424" ]
[]
[]
[]
[ "GO:0001913", "GO:0002424" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002420
2,420
natural killer cell mediated cytotoxicity directed against tumor cell target
biological_process
The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
[ "GOC:add", "ISBN:0781735149", "PMID:16730260" ]
Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.
[ "NK cell mediated cytotoxicity directed against tumor cell target" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002423", "GO:0042267" ]
[]
[]
[]
[ "GO:0002423", "GO:0042267" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002421
2,421
B cell antigen processing and presentation following pinocytosis
biological_process
B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
[ "GOC:add", "PMID:7543530" ]
null
[ "B lymphocyte antigen processing and presentation following pinocytosis", "B-cell antigen processing and presentation following pinocytosis", "B-lymphocyte antigen processing and presentation following pinocytosis" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002450", "GO:0002746" ]
[]
[]
[]
[ "GO:0002450", "GO:0002746" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002423
2,423
natural killer cell mediated immune response to tumor cell
biological_process
An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.
[ "GOC:add", "ISBN:0781735149", "PMID:16730260" ]
null
[]
[]
[]
[]
[]
[ "GO:0002228", "GO:0002418" ]
[]
[]
[]
[ "GO:0002228", "GO:0002418" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002424
2,424
T cell mediated immune response to tumor cell
biological_process
An immune response mediated by a T cell triggered in response to the presence of a tumor cell.
[ "GOC:add", "ISBN:0781735149", "PMID:16730260" ]
Note that this term includes tolerogenic responses to tumor cells mediated by responding T cells.
[]
[]
[]
[]
[]
[ "GO:0002418", "GO:0002456" ]
[]
[]
[]
[ "GO:0002418", "GO:0002456" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002425
2,425
tolerance induction in urogenital tract
biological_process
Tolerance induction taking place in the urogenital tract.
[ "GOC:jal" ]
null
[]
[]
[]
[]
[]
[ "GO:0002427" ]
[]
[]
[]
[ "GO:0002427" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002426
2,426
immunoglobulin production in mucosal tissue
biological_process
The synthesis and release of immunoglobulin in the mucosal tissue.
[ "GOC:jal" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "antibody production in mucosal tissue" ]
[ "EXACT" ]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0002381" ]
[ "part_of GO:0002385" ]
[ "part_of" ]
[ "GO:0002385" ]
[ "GO:0002381", "GO:0002385" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002427
2,427
mucosal tolerance induction
biological_process
Tolerance induction taking place in the mucosal tissues.
[ "GOC:jal" ]
null
[]
[]
[]
[]
[]
[ "GO:0002385", "GO:0002462" ]
[]
[]
[]
[ "GO:0002385", "GO:0002462" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002428
2,428
antigen processing and presentation of peptide antigen via MHC class Ib
biological_process
The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.
[ "GOC:add", "PMID:15928678" ]
null
[ "peptide antigen processing and presentation via MHC class Ib" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002475", "GO:0048002" ]
[]
[]
[]
[ "GO:0002475", "GO:0048002" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002429
2,429
immune response-activating cell surface receptor signaling pathway
biological_process
The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a cell, leading to the activation or perpetuation of an immune response.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "activation of immune response by cell surface receptor signaling pathway", "immune response-activating cell surface receptor signalling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002757", "GO:0002768" ]
[]
[]
[]
[ "GO:0002757", "GO:0002768" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002430
2,430
complement receptor mediated signaling pathway
biological_process
The series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "complement receptor mediated signalling pathway", "immune response-regulating cell surface receptor signalling pathway" ]
[ "EXACT", "BROAD" ]
[]
[]
[]
[ "GO:0002429" ]
[]
[]
[]
[ "GO:0002429" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002432
2,432
granuloma formation
biological_process
The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by v...
[ "GO_REF:0000022", "GOC:add", "ISBN:068340007X", "ISBN:0721601464", "ISBN:081533642X" ]
null
[]
[]
[]
[]
[]
[ "GO:0002252" ]
[ "part_of GO:0002544" ]
[ "part_of" ]
[ "GO:0002544" ]
[ "GO:0002252", "GO:0002544" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002433
2,433
obsolete immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
biological_process
OBSOLETE. An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
[ "GO_REF:0000022", "GOC:add", "GOC:bf", "ISBN:0781735149" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "immune response-regulating cell surface receptor signalling pathway involved in phagocytosis", "phagocytosis triggered by activation of immune response cell surface activating receptor" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
null
null
true
true
1
GO:0002434
2,434
immune complex clearance
biological_process
A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution.
[ "GO_REF:0000022", "GOC:add", "ISBN:068340007X" ]
null
[]
[]
[]
[]
[]
[ "GO:0002252" ]
[]
[]
[]
[ "GO:0002252" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002435
2,435
immune complex clearance by erythrocytes
biological_process
The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The pro...
[ "GOC:add", "PMID:11414352", "PMID:24022490" ]
null
[ "immune complex clearance by RBCs", "immune complex clearance by red blood cells" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "Wikipedia:Immune_complex" ]
[ "GO:0002434" ]
[]
[]
[]
[ "GO:0002434" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19884\" xsd:anyURI" ]
null
null
false
true
9
GO:0002436
2,436
immune complex clearance by monocytes and macrophages
biological_process
The process of immune complex clearance by monocytes or macrophages.
[ "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002434" ]
[]
[]
[]
[ "GO:0002434" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002437
2,437
inflammatory response to antigenic stimulus
biological_process
An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.
[ "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0006954", "GO:0006955" ]
[]
[]
[]
[ "GO:0006954", "GO:0006955" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002438
2,438
acute inflammatory response to antigenic stimulus
biological_process
An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002437", "GO:0002526" ]
[]
[]
[]
[ "GO:0002437", "GO:0002526" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002439
2,439
chronic inflammatory response to antigenic stimulus
biological_process
A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual.
[ "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002437", "GO:0002544" ]
[]
[]
[]
[ "GO:0002437", "GO:0002544" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002440
2,440
production of molecular mediator of immune response
biological_process
The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "production of cellular mediator of immune response" ]
[ "RELATED" ]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0002376", "GO:0010467" ]
[]
[]
[]
[ "GO:0002376", "GO:0010467" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002442
2,442
serotonin secretion involved in inflammatory response
biological_process
The regulated release of serotonin by a cell as part of an inflammatory response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "serotonin release involved in inflammatory response", "serotonin secretion involved in acute inflammatory response" ]
[ "RELATED", "BROAD" ]
[]
[]
[]
[ "GO:0001820" ]
[ "part_of GO:0002351" ]
[ "part_of" ]
[ "GO:0002351" ]
[ "GO:0001820", "GO:0002351" ]
[ "GO:0001820", "part_of GO:0006954" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002443
2,443
leukocyte mediated immunity
biological_process
Any process involved in the carrying out of an immune response by a leukocyte.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "cell-mediated immune response", "cellular immune response", "immune cell effector process", "immune cell mediated immunity", "leucocyte immune effector process", "leucocyte mediated immunity", "leukocyte immune effector process" ]
[ "RELATED", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[ "GO:0019723", "GO:0042087" ]
[]
[]
[ "GO:0002252" ]
[]
[]
[]
[ "GO:0002252" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002444
2,444
myeloid leukocyte mediated immunity
biological_process
Any process involved in the carrying out of an immune response by a myeloid leukocyte.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "myeloid leucocyte immune effector process", "myeloid leucocyte mediated immunity", "myeloid leukocyte immune effector process" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002443" ]
[]
[]
[]
[ "GO:0002443" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002445
2,445
type II hypersensitivity
biological_process
An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the dir...
[ "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[ "Wikipedia:Type_II_hypersensitivity" ]
[ "GO:0002444", "GO:0002524", "GO:0016064" ]
[]
[]
[]
[ "GO:0002444", "GO:0002524", "GO:0016064" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002446
2,446
neutrophil mediated immunity
biological_process
Any process involved in the carrying out of an immune response by a neutrophil.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002444" ]
[]
[]
[]
[ "GO:0002444" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002447
2,447
eosinophil mediated immunity
biological_process
Any process involved in the carrying out of an immune response by an eosinophil.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002444" ]
[]
[]
[]
[ "GO:0002444" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002448
2,448
mast cell mediated immunity
biological_process
Any process involved in the carrying out of an immune response by a mast cell.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002444" ]
[]
[]
[]
[ "GO:0002444" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002449
2,449
lymphocyte mediated immunity
biological_process
Any process involved in the carrying out of an immune response by a lymphocyte.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "cell-mediated immunity", "cellular immune response" ]
[ "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0002443" ]
[]
[]
[]
[ "GO:0002443" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002450
2,450
B cell antigen processing and presentation
biological_process
The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[ "B lymphocyte antigen processing and presentation", "B-cell antigen processing and presentation", "B-lymphocyte antigen processing and presentation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0019882" ]
[ "part_of GO:0019724" ]
[ "part_of" ]
[ "GO:0019724" ]
[ "GO:0019724", "GO:0019882" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002451
2,451
peripheral B cell tolerance induction
biological_process
Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.
[ "GOC:jal", "ISBN:0781735149" ]
null
[ "peripheral B lymphocyte tolerance induction", "peripheral B-cell tolerance induction", "peripheral B-lymphocyte tolerance induction" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002465", "GO:0002514", "GO:0019724" ]
[]
[]
[]
[ "GO:0002465", "GO:0002514", "GO:0019724" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002452
2,452
B cell receptor editing
biological_process
The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.
[ "GOC:jal", "ISBN:0781735149" ]
null
[ "B lymphocyte receptor editing", "B-cell receptor editing", "B-lymphocyte receptor editing" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016447" ]
[]
[]
[]
[ "GO:0016447" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002453
2,453
peripheral B cell anergy
biological_process
Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells.
[ "GOC:jal", "ISBN:0781735149" ]
null
[ "peripheral B lymphocyte anergy", "peripheral B-cell anergy", "peripheral B-lymphocyte anergy" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002515" ]
[ "part_of GO:0002451" ]
[ "part_of" ]
[ "GO:0002451" ]
[ "GO:0002451", "GO:0002515" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002454
2,454
peripheral B cell deletion
biological_process
The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.
[ "GOC:add", "GOC:jal", "GOC:mtg_apoptosis", "ISBN:0781735149" ]
null
[ "peripheral B lymphocyte deletion", "peripheral B-cell deletion", "peripheral B-lymphocyte deletion" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002516" ]
[ "part_of GO:0002451" ]
[ "part_of" ]
[ "GO:0002451" ]
[ "GO:0002451", "GO:0002516" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002455
2,455
humoral immune response mediated by circulating immunoglobulin
biological_process
An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "circulating antibody mediated immune response", "circulating immunoglobulin mediated immune response", "humoral defence mechanism", "humoral immune response mediated by circulating antibody" ]
[ "EXACT", "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0006959", "GO:0016064" ]
[]
[]
[]
[ "GO:0006959", "GO:0016064" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002456
2,456
T cell mediated immunity
biological_process
Any process involved in the carrying out of an immune response by a T cell.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "cell-mediated immunity", "cellular immune response", "T lymphocyte mediated immunity", "T-cell mediated immunity", "T-lymphocyte mediated immunity" ]
[ "BROAD", "BROAD", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002449", "GO:0002460" ]
[]
[]
[]
[ "GO:0002449", "GO:0002460" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002457
2,457
T cell antigen processing and presentation
biological_process
The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
[ "GOC:add", "PMID:11417857", "PMID:15120183" ]
null
[ "T lymphocyte antigen processing and presentation", "T-cell antigen processing and presentation", "T-lymphocyte antigen processing and presentation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0019882" ]
[ "part_of GO:0002456" ]
[ "part_of" ]
[ "GO:0002456" ]
[ "GO:0002456", "GO:0019882" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002458
2,458
peripheral T cell tolerance induction
biological_process
Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus.
[ "GOC:jal", "ISBN:0781735149" ]
null
[ "peripheral T lymphocyte tolerance induction", "peripheral T-cell tolerance induction", "peripheral T-lymphocyte tolerance induction" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002456", "GO:0002465", "GO:0002517" ]
[]
[]
[]
[ "GO:0002456", "GO:0002465", "GO:0002517" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002459
2,459
adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains
biological_process
An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposure...
[ "GOC:add", "GOC:mtg_sensu", "PMID:16373579" ]
null
[ "adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains", "adaptive immune response based on somatic recombination of VLR built from LRR domains", "adaptive immune response in jawless fish" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002250" ]
[]
[]
[]
[ "GO:0002250" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002460
2,460
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
biological_process
An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domain...
[ "GOC:add", "GOC:mtg_sensu", "ISBN:0781735149", "ISBN:1405196831" ]
null
[]
[]
[]
[]
[]
[ "GO:0002250" ]
[]
[]
[]
[ "GO:0002250" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002461
2,461
tolerance induction dependent upon immune response
biological_process
Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.
[ "GO_REF:0000022", "GOC:jal", "ISBN:0781735149" ]
null
[ "immune response-dependent tolerance induction" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002460", "GO:0002507" ]
[]
[]
[]
[ "GO:0002460", "GO:0002507" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002462
2,462
tolerance induction to nonself antigen
biological_process
Tolerance induction in response to nonself antigens.
[ "GO_REF:0000022", "GOC:jal", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002461" ]
[]
[]
[]
[ "GO:0002461" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002463
2,463
central tolerance induction to nonself antigen
biological_process
Tolerance induction to nonself antigens in the central lymphoid organs.
[ "GOC:jal", "PMID:12547504" ]
null
[]
[]
[]
[]
[]
[ "GO:0002462", "GO:0002508" ]
[]
[]
[]
[ "GO:0002462", "GO:0002508" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002464
2,464
peripheral tolerance induction to nonself antigen
biological_process
Tolerance induction to nonself antigens in the periphery.
[ "GOC:jal", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002462", "GO:0002465" ]
[]
[]
[]
[ "GO:0002462", "GO:0002465" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002465
2,465
peripheral tolerance induction
biological_process
Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.
[ "GO_REF:0000022", "GOC:jal", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002461" ]
[]
[]
[]
[ "GO:0002461" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002466
2,466
peripheral tolerance induction to self antigen
biological_process
Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.
[ "GOC:jal", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002465", "GO:0002513" ]
[]
[]
[]
[ "GO:0002465", "GO:0002513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002468
2,468
dendritic cell antigen processing and presentation
biological_process
The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002469
2,469
myeloid dendritic cell antigen processing and presentation
biological_process
The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0002468" ]
[]
[]
[]
[ "GO:0002468" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002470
2,470
plasmacytoid dendritic cell antigen processing and presentation
biological_process
The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0002468" ]
[]
[]
[]
[ "GO:0002468" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002471
2,471
monocyte antigen processing and presentation
biological_process
The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
[ "GOC:add", "PMID:11200054" ]
null
[]
[]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002472
2,472
macrophage antigen processing and presentation
biological_process
The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002473
2,473
non-professional antigen presenting cell antigen processing and presentation
biological_process
The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002474
2,474
antigen processing and presentation of peptide antigen via MHC class I
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
[ "GOC:add", "ISBN:0781735149", "PMID:15224092", "PMID:15771591" ]
null
[ "peptide antigen processing and presentation via MHC class I" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-983169 \"Class I MHC mediated antigen processing & presentation\"" ]
[ "GO:0048002" ]
[]
[]
[]
[ "GO:0048002" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002475
2,475
antigen processing and presentation via MHC class Ib
biological_process
The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
[ "GOC:add", "PMID:15928678", "PMID:15928680" ]
null
[]
[]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002476
2,476
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical clas...
[ "GOC:add", "PMID:15928678" ]
null
[ "endogenous peptide antigen processing and presentation via MHC class Ib" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002428", "GO:0002483" ]
[]
[]
[]
[ "GO:0002428", "GO:0002483" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002477
2,477
antigen processing and presentation of exogenous peptide antigen via MHC class Ib
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class ...
[ "GOC:add", "PMID:15928678" ]
null
[ "exogenous peptide antigen processing and presentation via MHC class Ib" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002428", "GO:0002478" ]
[]
[]
[]
[ "GO:0002428", "GO:0002478" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002478
2,478
antigen processing and presentation of exogenous peptide antigen
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "exogenous peptide antigen processing and presentation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019884", "GO:0048002" ]
[]
[]
[]
[ "GO:0019884", "GO:0048002" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002479
2,479
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exo...
[ "GOC:add", "PMID:15224093", "PMID:15771591", "PMID:16181335" ]
null
[ "cross presentation", "cross-presentation", "exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent", "TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I", "TAP-dependent exogenous peptide antigen processing and presentation via MHC c...
[ "BROAD", "BROAD", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1236973 \"Cross-presentation of particulate exogenous antigens (phagosomes)\"", "Reactome:R-HSA-1236974 \"ER-Phagosome pathway\"", "Reactome:R-HSA-1236978 \"Cross-presentation of soluble exogenous antigens (endosomes)\"" ]
[ "GO:0042590" ]
[]
[]
[]
[ "GO:0042590" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002480
2,480
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment o...
[ "GOC:add", "PMID:15224093", "PMID:15771591", "PMID:16181335" ]
null
[ "cross presentation", "cross-presentation", "exogenous peptide antigen processing and presentation via MHC class I, TAP-independent", "TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I", "TAP-independent exogenous peptide antigen processing and presentation via...
[ "BROAD", "BROAD", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1236977 \"Endosomal/Vacuolar pathway\"" ]
[ "GO:0042590" ]
[]
[]
[]
[ "GO:0042590" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002481
2,481
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger ex...
[ "GOC:add", "PMID:15928678" ]
null
[ "exogenous peptide antigen processing and presentation via MHC class Ib, TAP-dependent", "TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class Ib", "TAP-dependent exogenous peptide antigen processing and presentation via MHC class Ib" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002477" ]
[]
[]
[]
[ "GO:0002477" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002482
2,482
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment ...
[ "GOC:add", "PMID:15928678" ]
null
[ "exogenous peptide antigen processing and presentation via MHC class Ib, TAP-independent", "TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class Ib", "TAP-independent exogenous peptide antigen processing and presentation via MHC class Ib" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002477" ]
[]
[]
[]
[ "GO:0002477" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002483
2,483
antigen processing and presentation of endogenous peptide antigen
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "endogenous peptide antigen processing and presentation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019883", "GO:0048002" ]
[]
[]
[]
[ "GO:0019883", "GO:0048002" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002484
2,484
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within t...
[ "GOC:add", "ISBN:0781735149", "PMID:14647477", "PMID:15771591" ]
null
[ "endogenous peptide antigen processing and presentation via MHC class I via ER pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019885" ]
[]
[]
[]
[ "GO:0019885" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002485
2,485
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degr...
[ "GOC:add", "ISBN:0781735149", "PMID:14647477", "PMID:15771591" ]
null
[ "endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent", "TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway", "TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER p...
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002484" ]
[]
[]
[]
[ "GO:0002484" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002487
2,487
antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I ...
[ "GOC:add", "PMID:10631943" ]
null
[ "endogenous peptide antigen processing and presentation via MHC class I via endolysosomal pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019885" ]
[]
[]
[]
[ "GO:0019885" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002488
2,488
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within ...
[ "GOC:add", "PMID:15928678" ]
null
[ "endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002476" ]
[]
[]
[]
[ "GO:0002476" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002489
2,489
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger e...
[ "GOC:add", "PMID:15928678" ]
null
[ "endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-dependent", "TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway", "TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via E...
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002488" ]
[]
[]
[]
[ "GO:0002488" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002490
2,490
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment...
[ "GOC:add", "PMID:15928678" ]
null
[ "endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent", "TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway", "TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib...
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002488" ]
[]
[]
[]
[ "GO:0002488" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002492
2,492
peptide antigen assembly with MHC class Ib protein complex
biological_process
The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
[ "GOC:add", "PMID:15928678" ]
null
[]
[]
[]
[]
[]
[ "GO:0002501" ]
[ "part_of GO:0002398", "part_of GO:0002428" ]
[ "part_of", "part_of" ]
[ "GO:0002398", "GO:0002428" ]
[ "GO:0002398", "GO:0002428", "GO:0002501" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002493
2,493
lipid antigen assembly with MHC class Ib protein complex
biological_process
The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.
[ "GOC:add", "PMID:15928678", "PMID:15928680" ]
null
[]
[]
[]
[]
[]
[ "GO:0065005" ]
[ "part_of GO:0002398", "part_of GO:0048003" ]
[ "part_of", "part_of" ]
[ "GO:0002398", "GO:0048003" ]
[ "GO:0002398", "GO:0048003", "GO:0065005" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002494
2,494
lipid antigen transport
biological_process
The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
[ "GOC:add", "PMID:15928678", "PMID:15928680" ]
null
[]
[]
[]
[]
[]
[ "GO:0006869" ]
[ "part_of GO:0048003" ]
[ "part_of" ]
[ "GO:0048003" ]
[ "GO:0006869", "GO:0048003" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002495
2,495
antigen processing and presentation of peptide antigen via MHC class II
biological_process
The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
[ "GOC:add", "ISBN:0781735149", "PMID:15531770", "PMID:15771591" ]
null
[ "peptide antigen processing and presentation via MHC class II" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002504", "GO:0048002" ]
[]
[]
[]
[ "GO:0002504", "GO:0048002" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002496
2,496
proteolysis associated with antigen processing and presentation
biological_process
The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.
[ "GOC:add", "ISBN:0781735149", "PMID:15224092", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0006508" ]
[ "part_of GO:0048002" ]
[ "part_of" ]
[ "GO:0048002" ]
[ "GO:0006508", "GO:0048002" ]
[ "GO:0006508", "part_of GO:0048002" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002497
2,497
proteasomal proteolysis associated with antigen processing and presentation
biological_process
The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.
[ "GOC:add", "ISBN:0781735149", "PMID:15224092", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0002496" ]
[]
[]
[]
[ "GO:0002496" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002498
2,498
proteolysis within endoplasmic reticulum associated with antigen processing and presentation
biological_process
The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.
[ "GOC:add", "ISBN:0781735149", "PMID:15224092", "PMID:15771591" ]
null
[ "endoplasmic reticulum proteolysis associated with antigen processing and presentation", "ER proteolysis associated with antigen processing and presentation", "proteolysis within ER associated with antigen processing and presentation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002496" ]
[]
[]
[]
[ "GO:0002496" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002499
2,499
proteolysis within endosome associated with antigen processing and presentation
biological_process
The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[ "endosomal proteolysis associated with antigen processing and presentation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002496" ]
[ "occurs_in GO:0005768" ]
[ "occurs_in" ]
[ "GO:0005768" ]
[ "GO:0002496", "GO:0005768" ]
[ "GO:0002496", "occurs_in GO:0005768" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002500
2,500
proteolysis within lysosome associated with antigen processing and presentation
biological_process
The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[ "lysosomal proteolysis associated with antigen processing and presentation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002496" ]
[ "occurs_in GO:0005764" ]
[ "occurs_in" ]
[ "GO:0005764" ]
[ "GO:0002496", "GO:0005764" ]
[ "GO:0002496", "occurs_in GO:0005764" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002501
2,501
peptide antigen assembly with MHC protein complex
biological_process
The binding of a peptide to the antigen binding groove of an MHC protein complex.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0065003" ]
[ "part_of GO:0002396", "part_of GO:0048002" ]
[ "part_of", "part_of" ]
[ "GO:0002396", "GO:0048002" ]
[ "GO:0002396", "GO:0048002", "GO:0065003" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002502
2,502
peptide antigen assembly with MHC class I protein complex
biological_process
The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0002501" ]
[ "part_of GO:0002397", "part_of GO:0002474" ]
[ "part_of", "part_of" ]
[ "GO:0002397", "GO:0002474" ]
[ "GO:0002397", "GO:0002474", "GO:0002501" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002503
2,503
peptide antigen assembly with MHC class II protein complex
biological_process
The binding of a peptide to the antigen binding groove of an MHC class II protein complex.
[ "GOC:add", "ISBN:0781735149", "PMID:15771591" ]
null
[]
[]
[]
[]
[]
[ "GO:0002501" ]
[ "part_of GO:0002399", "part_of GO:0002495" ]
[ "part_of", "part_of" ]
[ "GO:0002399", "GO:0002495" ]
[ "GO:0002399", "GO:0002495", "GO:0002501" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002504
2,504
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
biological_process
The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.
[ "GOC:add", "ISBN:0781735149", "PMID:15531770", "PMID:15771591", "PMID:16153240" ]
null
[ "peptide or polysaccharide antigen processing and presentation of via MHC class II" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[ "GO:0019882" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002505
2,505
antigen processing and presentation of polysaccharide antigen via MHC class II
biological_process
The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.
[ "GOC:add", "PMID:16153240" ]
null
[ "polysaccharide antigen processing and presentation via MHC class II" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002504" ]
[]
[]
[]
[ "GO:0002504" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002507
2,507
tolerance induction
biological_process
A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.
[ "GO_REF:0000022", "GOC:jal", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002376" ]
[ "part_of GO:0002520" ]
[ "part_of" ]
[ "GO:0002520" ]
[ "GO:0002376", "GO:0002520" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002508
2,508
central tolerance induction
biological_process
Tolerance induction in the central lymphoid organs: the thymus and bone marrow.
[ "GO_REF:0000022", "GOC:jal", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002507" ]
[]
[]
[]
[ "GO:0002507" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002509
2,509
central tolerance induction to self antigen
biological_process
Tolerance induction in the central lymphoid organs directed at self antigens.
[ "GOC:jal", "ISBN:0781735149", "PMID:16460922" ]
null
[]
[]
[]
[]
[]
[ "GO:0002508", "GO:0002513" ]
[]
[]
[]
[ "GO:0002508", "GO:0002513" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002510
2,510
central B cell tolerance induction
biological_process
Tolerance induction of B cells in the bone marrow.
[ "GOC:jal", "PMID:16460922" ]
null
[ "central B lymphocyte tolerance induction", "central B-cell tolerance induction", "central B-lymphocyte tolerance induction" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002508", "GO:0002514" ]
[]
[]
[]
[ "GO:0002508", "GO:0002514" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002511
2,511
central B cell receptor editing
biological_process
Receptor editing occurring in B cells in the bone marrow.
[ "GOC:jal", "PMID:16460922" ]
null
[ "central B lymphocyte receptor editing", "central B-cell receptor editing", "central B-lymphocyte receptor editing" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002452" ]
[]
[]
[]
[ "GO:0002452" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002512
2,512
central T cell tolerance induction
biological_process
Tolerance induction of T cells in the thymus.
[ "GOC:jal", "ISBN:0781735149" ]
null
[ "central T lymphocyte tolerance induction", "central T-cell tolerance induction", "central T-lymphocyte tolerance induction" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002508", "GO:0002517" ]
[]
[]
[]
[ "GO:0002508", "GO:0002517" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002513
2,513
tolerance induction to self antigen
biological_process
Tolerance induction directed at self antigens.
[ "GO_REF:0000022", "GOC:jal", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002507" ]
[]
[]
[]
[ "GO:0002507" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7