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GO

Dataset card Data Studio Files
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 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0002167
2,167
VRK3/VHR/ERK complex
cellular_component
A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway.
[ "GOC:hjd", "PMID:16845380" ]
null
[]
[]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
hjd
2010-03-04T01:15:05Z
false
true
6
GO:0002168
2,168
instar larval development
biological_process
The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster.
[ "GOC:bf", "GOC:mtg_sensu" ]
null
[]
[]
[]
[]
[]
[ "GO:0002164", "GO:0002165" ]
[]
[]
[]
[ "GO:0002164", "GO:0002165" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002169
2,169
obsolete 3-methylcrotonyl-CoA carboxylase complex, mitochondrial
cellular_component
OBSOLETE. A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity ...
[ "GOC:bf", "GOC:hjd", "PMID:15868465", "PMID:17360195", "PMID:22869039" ]
The reason for obsoletion is that this term is equivalent to GO:1905202 methylcrotonoyl-CoA carboxylase complex.
[ "mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme", "mitochondrial MCCC complex", "mitochondrial methylcrotonoyl-CoA carboxylase complex" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:1905202" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28023\" xsd:anyURI" ]
hjd
2010-03-15T04:58:08Z
true
true
4
GO:0002170
2,170
high-affinity IgA receptor activity
molecular_function
Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
[ "GOC:hjd", "GOC:signaling" ]
null
[ "high affinity IgA receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019766" ]
[]
[]
[]
[ "GO:0019766" ]
[]
[]
[]
[]
[]
[]
hjd
2010-05-06T05:00:11Z
false
true
1
GO:0002171
2,171
low-affinity IgA receptor activity
molecular_function
Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
[ "GOC:hjd", "GOC:signaling" ]
null
[ "low affinity IgA receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0019766" ]
[]
[]
[]
[ "GO:0019766" ]
[]
[]
[]
[]
[]
[]
hjd
2010-05-06T05:01:41Z
false
true
2
GO:0002172
2,172
high-affinity IgM receptor activity
molecular_function
Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
[ "GOC:hjd", "GOC:signaling" ]
null
[ "high affinity IgM receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001793" ]
[]
[]
[]
[ "GO:0001793" ]
[]
[]
[]
[]
[]
[]
hjd
2010-05-06T05:03:26Z
false
true
7
GO:0002173
2,173
low-affinity IgM receptor activity
molecular_function
Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
[ "GOC:hjd", "GOC:signaling" ]
null
[ "low affinity IgM receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001793" ]
[]
[]
[]
[ "GO:0001793" ]
[]
[]
[]
[]
[]
[]
hjd
2010-05-06T05:04:24Z
false
true
9
GO:0002174
2,174
mammary stem cell proliferation
biological_process
The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ.
[ "PMID:15987436" ]
null
[]
[]
[]
[]
[]
[ "GO:0008283" ]
[ "part_of GO:0030879" ]
[ "part_of" ]
[ "GO:0030879" ]
[ "GO:0008283", "GO:0030879" ]
[]
[]
[]
[]
[]
[]
hjd
2010-09-14T01:19:45Z
false
true
5
GO:0002175
2,175
protein localization to paranode region of axon
biological_process
A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon.
[ "PMID:18803321" ]
null
[ "protein localisation to paranode region of axon" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0099612" ]
[]
[]
[]
[ "GO:0099612" ]
[]
[]
[]
[]
[]
[]
hjd
2010-11-15T10:28:20Z
false
true
1
GO:0002177
2,177
manchette
cellular_component
A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments.
[ "GOC:krc", "PMID:15018141", "PMID:22319670", "PMID:24440897", "PMID:26792866" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0015630" ]
[ "part_of" ]
[ "GO:0015630" ]
[ "GO:0015630", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
hjd
2010-12-01T02:31:43Z
false
true
8
GO:0002178
2,178
palmitoyltransferase complex
cellular_component
A protein complex with palmitoyltransferase activity.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[ "GO:1990234" ]
[]
[]
[]
[]
[]
[]
hjd
2010-12-03T10:49:17Z
false
true
1
GO:0002179
2,179
homodimeric serine palmitoyltransferase complex
cellular_component
A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine.
[ "GOC:hjd" ]
This complex occurs primarily in bacteria.
[]
[]
[]
[]
[]
[ "GO:0002178" ]
[]
[]
[]
[ "GO:0002178" ]
[]
[]
[]
[]
[]
[]
hjd
2010-12-03T10:50:59Z
false
true
7
GO:0002180
2,180
5-lipoxygenase complex
cellular_component
An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.
[ "PMID:19075240" ]
null
[]
[]
[]
[]
[]
[ "GO:0098796", "GO:0140513", "GO:1990204" ]
[ "part_of GO:0031965" ]
[ "part_of" ]
[ "GO:0031965" ]
[ "GO:0031965", "GO:0098796", "GO:0140513", "GO:1990204" ]
[]
[]
[]
[]
[]
[]
hjd
2011-06-09T01:05:53Z
false
true
5
GO:0002181
2,181
cytoplasmic translation
biological_process
The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
[ "GOC:hjd" ]
Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms.
[]
[]
[]
[ "goslim_generic", "goslim_pombe", "goslim_yeast" ]
[]
[ "GO:0006412" ]
[]
[]
[]
[ "GO:0006412" ]
[]
[]
[]
[]
[]
[]
hjd
2011-06-09T03:11:53Z
false
true
2
GO:0002183
2,183
cytoplasmic translational initiation
biological_process
The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0006413" ]
[ "part_of GO:0002181" ]
[ "part_of" ]
[ "GO:0002181" ]
[ "GO:0002181", "GO:0006413" ]
[ "GO:0006413", "part_of GO:0002181" ]
[]
[]
[]
[]
[]
hjd
2011-06-09T03:15:48Z
false
true
8
GO:0002184
2,184
cytoplasmic translational termination
biological_process
The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0006415" ]
[ "occurs_in GO:0005829", "part_of GO:0002181" ]
[ "occurs_in", "part_of" ]
[ "GO:0005829", "GO:0002181" ]
[ "GO:0002181", "GO:0005829", "GO:0006415" ]
[ "GO:0006415", "occurs_in GO:0005829" ]
[]
[]
[]
[]
[]
hjd
2011-06-09T03:17:13Z
false
true
6
GO:0002185
2,185
creatine kinase complex
cellular_component
A protein complex having creatine kinase activity.
[ "GOC:hjd" ]
null
[]
[]
[]
[]
[]
[ "GO:0061695" ]
[]
[]
[]
[ "GO:0061695" ]
[]
[]
[]
[]
[]
[]
hjd
2011-06-14T02:12:19Z
false
true
5
GO:0002186
2,186
cytosolic creatine kinase complex
cellular_component
A dimeric protein complex having creatine kinase activity.
[ "PMID:173175" ]
null
[]
[]
[]
[]
[]
[ "GO:0002185" ]
[ "part_of GO:0005829" ]
[ "part_of" ]
[ "GO:0005829" ]
[ "GO:0002185", "GO:0005829" ]
[ "GO:0002185", "part_of GO:0005829" ]
[]
[]
[]
[]
[]
hjd
2011-06-14T02:14:16Z
false
true
6
GO:0002187
2,187
mitochondrial creatine kinase complex
cellular_component
An octomeric protein complex having creatine kinase activity.
[ "PMID:16236486" ]
null
[]
[]
[]
[]
[]
[ "GO:0002185", "GO:0098798" ]
[]
[]
[]
[ "GO:0002185", "GO:0098798" ]
[ "GO:0002185", "part_of GO:0005739" ]
[]
[]
[]
[]
[]
hjd
2011-06-14T02:15:29Z
false
true
4
GO:0002188
2,188
translation reinitiation
biological_process
A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is ...
[ "PMID:18056426", "PMID:18765792" ]
null
[]
[]
[]
[]
[]
[ "GO:0002183" ]
[]
[]
[]
[ "GO:0002183" ]
[]
[]
[]
[]
[]
[]
hjd
2011-06-22T12:31:13Z
false
true
9
GO:0002189
2,189
ribose phosphate diphosphokinase complex
cellular_component
A protein complex having ribose phosphate diphosphokinase activity.
[ "GO:hjd", "PMID:9348095" ]
In mammals, the complex consists of two non-identical catalytic subunits and two non-identical regulatory subunits.
[ "phosphoribosylpyrophosphate synthetase complex", "PRPP synthetase complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0061695" ]
[]
[]
[]
[ "GO:0061695" ]
[]
[]
[]
[]
[]
[]
hjd
2011-06-27T02:49:33Z
false
true
6
GO:0002190
2,190
cap-independent translational initiation
biological_process
The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation.
[ "PMID:17284590" ]
null
[]
[]
[]
[]
[]
[ "GO:0002183" ]
[]
[]
[]
[ "GO:0002183" ]
[]
[]
[]
[]
[]
[]
hjd
2011-08-11T02:16:05Z
false
true
1
GO:0002191
2,191
cap-dependent translational initiation
biological_process
The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codo...
[ "PMID:17284590", "PMID:19604130" ]
null
[]
[]
[]
[]
[]
[ "GO:0002183" ]
[ "has_part GO:0160296" ]
[ "has_part" ]
[ "GO:0160296" ]
[ "GO:0002183", "GO:0160296" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30674\" xsd:anyURI" ]
hjd
2011-08-11T02:20:24Z
false
true
3
GO:0002192
2,192
IRES-dependent translational initiation of linear mRNA
biological_process
The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.
[ "PMID:17284590" ]
null
[]
[]
[]
[]
[]
[ "GO:0110017" ]
[ "has_part GO:0160297" ]
[ "has_part" ]
[ "GO:0160297" ]
[ "GO:0110017", "GO:0160297" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30674\" xsd:anyURI" ]
hjd
2011-08-11T02:32:45Z
false
true
6
GO:0002193
2,193
MAML1-RBP-Jkappa- ICN1 complex
cellular_component
A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
[ "CORUM:2949", "PMID:16510869" ]
null
[ "MAML1-CSL-ICN1", "MAML1-CSL-Notch1 complex", "MAML1-RBP-Jkappa-Notch1 complex" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
hjd
2011-08-11T04:08:18Z
false
true
2
GO:0002194
2,194
hepatocyte cell migration
biological_process
The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes.
[ "CL:0000182", "PMID:9794819" ]
null
[]
[]
[]
[]
[]
[ "GO:0016477" ]
[]
[]
[]
[ "GO:0016477" ]
[]
[]
[]
[]
[]
[]
hjd
2011-08-30T04:27:39Z
false
true
5
GO:0002196
2,196
Ser-tRNA(Ala) deacylase activity
molecular_function
Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).
[ "GOC:hjd", "PMID:21285375" ]
null
[]
[]
[]
[]
[]
[ "GO:0002161" ]
[]
[]
[]
[ "GO:0002161" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29746\" xsd:anyURI" ]
hjd
2011-09-30T02:18:50Z
false
true
4
GO:0002197
2,197
xanthine dehydrogenase complex
cellular_component
A homodimeric protein complex having xanthine dehydrogenase activity.
[ "GOC:hjd", "PMID:8224915" ]
null
[]
[]
[]
[]
[]
[ "GO:1990204" ]
[]
[]
[]
[ "GO:1990204" ]
[]
[]
[]
[]
[]
[]
hjd
2011-10-03T03:55:57Z
false
true
2
GO:0002198
2,198
obsolete S/G2 transition of mitotic cell cycle
biological_process
OBSOLETE. The transition from a cell in the S phase to the G2 phase.
[ "GOC:hjd", "GOC:mtg_cell_cycle", "PMID:15161931" ]
This term was made obsolete because it does not refer to a real biological process.
[ "S/G2 transition of mitotic cell cycle" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
hjd
2011-11-02T10:36:58Z
true
true
1
GO:0002199
2,199
zona pellucida receptor complex
cellular_component
A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction.
[ "GOC:hjd", "PMID:21880732" ]
null
[ "sperm protein complex I" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0032991" ]
[ "has_part GO:0005832" ]
[ "has_part" ]
[ "GO:0005832" ]
[ "GO:0005832", "GO:0032991" ]
[]
[]
[]
[]
[]
[]
hjd
2011-12-23T01:33:23Z
false
true
5
GO:0002201
2,201
somatic diversification of DSCAM-based immune receptors
biological_process
The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects.
[ "GOC:add", "PMID:16261174" ]
Note that this type of immune receptor may not be limited to insects.
[]
[]
[]
[]
[]
[ "GO:0002200" ]
[]
[]
[]
[ "GO:0002200" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002202
2,202
somatic diversification of variable lymphocyte receptors of jawless fish
biological_process
The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish.
[ "GOC:add", "PMID:16373579" ]
Note that jawless fish refers to both lampreys (Petremyzontidae, ncbi_taxonomy_id:7746) and hagfish (Myxinidae, ncbi_taxonomy_id:7762).
[]
[]
[]
[]
[]
[ "GO:0002200" ]
[]
[]
[]
[ "GO:0002200" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002203
2,203
proteolysis by cytosolic proteases associated with antigen processing and presentation
biological_process
The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation.
[ "GOC:add", "ISBN:0781735149", "PMID:15224092", "PMID:15771591" ]
Note that a separate term covers proteolysis by the proteasome complex (proteasomal proteolysis associated with antigen processing and presentation ; GO:0002497).
[]
[]
[]
[]
[]
[ "GO:0002496" ]
[]
[]
[]
[ "GO:0002496" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002204
2,204
somatic recombination of immunoglobulin genes involved in immune response
biological_process
The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "somatic recombination of antibody genes during immune response", "somatic recombination of immunoglobulin genes during immune response" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0002208", "GO:0016447" ]
[]
[]
[]
[ "GO:0002208", "GO:0016447" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002205
2,205
obsolete somatic hypermutation of immunoglobulin genes involved in immune response
biological_process
OBSOLETE. Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response.
[ "GOC:add", "ISBN:0781735149", "PMID:11205333", "PMID:14991701" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "somatic hypermutation of antibody genes during immune response", "somatic hypermutation of immunoglobulin genes during immune response" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31306\" xsd:anyURI" ]
null
null
true
true
2
GO:0002206
2,206
gene conversion of immunoglobulin genes
biological_process
The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion.
[ "GOC:add", "PMID:14991701" ]
null
[ "gene conversion of antibody genes" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002565", "GO:0016445", "GO:0035822" ]
[]
[]
[]
[ "GO:0002565", "GO:0016445", "GO:0035822" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002207
2,207
obsolete gene conversion of immunoglobulin genes involved in immune response
biological_process
OBSOLETE. The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response.
[ "GOC:add", "PMID:14991701" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "gene conversion of antibody genes during immune response", "gene conversion of immunoglobulin genes during immune response" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31306\" xsd:anyURI" ]
null
null
true
true
3
GO:0002209
2,209
behavioral defense response
biological_process
A behavioral response seeking to protect an organism from an perceived external threat to that organism.
[ "GO_REF:0000022", "GOC:add" ]
null
[ "behavioural defense response" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006952", "GO:0007610" ]
[]
[]
[]
[ "GO:0006952", "GO:0007610" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002210
2,210
behavioral response to wounding
biological_process
A behavioral response resulting from wounding.
[ "GO_REF:0000022", "GOC:add" ]
null
[ "behavioural response to wounding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007610", "GO:0009611" ]
[]
[]
[]
[ "GO:0007610", "GO:0009611" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002211
2,211
behavioral defense response to insect
biological_process
A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.
[ "GOC:add" ]
null
[ "behavioural defense response to insect" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002209", "GO:0002213" ]
[]
[]
[]
[ "GO:0002209", "GO:0002213" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002213
2,213
defense response to insect
biological_process
A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.
[ "GOC:add" ]
null
[ "physiological defense response to insect" ]
[ "EXACT" ]
[ "GO:0002214" ]
[]
[]
[ "GO:0006952", "GO:0051707" ]
[]
[]
[]
[ "GO:0006952", "GO:0051707" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002215
2,215
defense response to nematode
biological_process
A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
[ "GOC:add", "PMID:11516579", "PMID:14506883" ]
null
[ "physiological defense response to nematode" ]
[ "EXACT" ]
[ "GO:0002216" ]
[]
[]
[ "GO:0006952", "GO:0051707" ]
[]
[]
[]
[ "GO:0006952", "GO:0051707" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002218
2,218
activation of innate immune response
biological_process
Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any ...
[ "GO_REF:0000022", "GOC:add", "GOC:mtg_sensu", "ISBN:0781735149", "PMID:15199967", "PMID:16177805" ]
null
[]
[]
[ "GO:0002219" ]
[]
[]
[ "GO:0002253", "GO:0045089" ]
[]
[]
[]
[ "GO:0002253", "GO:0045089" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002220
2,220
innate immune response activating cell surface receptor signaling pathway
biological_process
The series of molecular signals initiated by a ligand binding to a cell surface receptor that leads to the activation of an innate immune response.
[ "GOC:add", "ISBN:0781735149", "PMID:15199967" ]
null
[ "activation of innate immune response by cell surface receptor signaling pathway", "innate immune response activating cell surface receptor signalling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002429", "GO:0002758" ]
[]
[]
[]
[ "GO:0002429", "GO:0002758" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002222
2,222
stimulatory killer cell immunoglobulin-like receptor signaling pathway
biological_process
The series of molecular signals initiated by a ligand binding to a killer cell immunoglobulin-like receptor capable of cellular activation.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "stimulatory killer cell immunoglobulin-like receptor signalling pathway", "stimulatory KIR signaling pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002220" ]
[]
[]
[]
[ "GO:0002220" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002223
2,223
stimulatory C-type lectin receptor signaling pathway
biological_process
The series of molecular signals initiated by the binding of C-type lectin to its receptor on the surface of a target cell, and resulting in cellular activation.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "stimulatory C-type lectin receptor signalling pathway", "stimulatory Ly49 family receptor signaling pathway" ]
[ "EXACT", "NARROW" ]
[]
[]
[ "Reactome:R-HSA-5621481 \"C-type lectin receptors (CLRs)\"" ]
[ "GO:0002220", "GO:1990858" ]
[]
[]
[]
[ "GO:0002220", "GO:1990858" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002225
2,225
positive regulation of antimicrobial peptide production
biological_process
Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.
[ "GOC:add", "PMID:11807545" ]
null
[ "activation of antimicrobial peptide production", "antimicrobial peptide induction", "stimulation of antimicrobial peptide production", "up regulation of antimicrobial peptide production", "up-regulation of antimicrobial peptide production", "upregulation of antimicrobial peptide production" ]
[ "NARROW", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002702", "GO:0002760", "GO:0002784" ]
[ "positively_regulates GO:0002775" ]
[ "positively_regulates" ]
[ "GO:0002775" ]
[ "GO:0002702", "GO:0002760", "GO:0002775", "GO:0002784" ]
[ "GO:0065007", "positively_regulates GO:0002775" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002227
2,227
innate immune response in mucosa
biological_process
Any process of the innate immune response that takes place in the mucosal tissues.
[ "GOC:add", "PMID:10719665", "PMID:15971105" ]
null
[]
[]
[]
[]
[]
[ "GO:0002385", "GO:0045087" ]
[]
[]
[]
[ "GO:0002385", "GO:0045087" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002228
2,228
natural killer cell mediated immunity
biological_process
The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "NK cell mediated immunity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002449", "GO:0045087" ]
[]
[]
[]
[ "GO:0002449", "GO:0045087" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002229
2,229
defense response to oomycetes
biological_process
Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.
[ "GOC:add", "PMID:16497589" ]
null
[]
[]
[]
[]
[]
[ "GO:0002239", "GO:0006952" ]
[]
[]
[]
[ "GO:0002239", "GO:0006952" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002230
2,230
positive regulation of defense response to virus by host
biological_process
Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
[ "GOC:add", "GOC:dph", "GOC:tb", "ISBN:0781735149" ]
null
[ "activation of antiviral response by host", "positive regulation of antiviral response by host", "stimulation of antiviral response by host", "up regulation of antiviral response by host", "up-regulation of antiviral response by host", "upregulation of antiviral response by host" ]
[ "NARROW", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0050691" ]
[]
[]
[]
[ "GO:0050691" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002231
2,231
detection of oomycetes
biological_process
The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal.
[ "GOC:add", "PMID:15922649" ]
null
[]
[]
[]
[]
[]
[ "GO:0002239", "GO:0098543" ]
[]
[]
[]
[ "GO:0002239", "GO:0098543" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002232
2,232
leukocyte chemotaxis involved in inflammatory response
biological_process
The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "immune cell chemotaxis during inflammatory response", "leucocyte chemotaxis during inflammatory response", "leukocyte chemotaxis during inflammatory response" ]
[ "RELATED", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0002523", "GO:0030595" ]
[]
[]
[]
[ "GO:0002523", "GO:0030595" ]
[ "GO:0030595", "part_of GO:0006954" ]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002233
2,233
leukocyte chemotaxis involved in immune response
biological_process
The movement of an immune cell in response to an external stimulus a part of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "immune cell chemotaxis during immune response", "leucocyte chemotaxis during immune response" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002522", "GO:0030595" ]
[]
[]
[]
[ "GO:0002522", "GO:0030595" ]
[ "GO:0030595", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002234
2,234
detection of endoplasmic reticulum overloading
biological_process
The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.
[ "GOC:add", "PMID:10390516" ]
null
[ "detection of ER overloading" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006983", "GO:0009595" ]
[]
[]
[]
[ "GO:0006983", "GO:0009595" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002235
2,235
detection of unfolded protein
biological_process
The series of events in which an unfolded protein stimulus is received and converted into a molecular signal.
[ "GOC:add", "PMID:15226511", "PMID:7765470" ]
null
[]
[]
[]
[]
[]
[ "GO:0006986", "GO:0009593" ]
[]
[]
[]
[ "GO:0006986", "GO:0009593" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002236
2,236
detection of misfolded protein
biological_process
The series of events in which a misfolded protein stimulus is received and converted into a molecular signal.
[ "GOC:add", "PMID:15226511" ]
null
[]
[]
[]
[]
[]
[ "GO:0009593", "GO:0051788" ]
[]
[]
[]
[ "GO:0009593", "GO:0051788" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002237
2,237
response to molecule of bacterial origin
biological_process
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
[ "GOC:rl", "GOC:sm" ]
null
[ "response to bacteria associated molecule", "response to bacterial associated molecule", "response to bacterium associated molecule" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043207" ]
[ "part_of GO:0009617" ]
[ "part_of" ]
[ "GO:0009617" ]
[ "GO:0009617", "GO:0043207" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002239
2,239
response to oomycetes
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.
[ "GOC:add", "PMID:16497589" ]
null
[]
[]
[]
[]
[]
[ "GO:0051707" ]
[]
[]
[]
[ "GO:0051707" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002241
2,241
response to parasitic plant
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant.
[ "GOC:add", "PMID:16547862" ]
null
[]
[]
[]
[]
[]
[ "GO:0009608" ]
[]
[]
[]
[ "GO:0009608" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002242
2,242
defense response to parasitic plant
biological_process
Reactions triggered in response to the presence of a parasitic plant that act to protect an organism.
[ "GOC:add" ]
null
[]
[]
[]
[]
[]
[ "GO:0002241", "GO:0098542" ]
[]
[]
[]
[ "GO:0002241", "GO:0098542" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002243
2,243
detection of parasitic plant
biological_process
The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal.
[ "GOC:add", "PMID:16547862" ]
null
[]
[]
[]
[]
[]
[ "GO:0002241", "GO:0009602" ]
[]
[]
[]
[ "GO:0002241", "GO:0009602" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002244
2,244
hematopoietic progenitor cell differentiation
biological_process
The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
[ "GOC:add", "GOC:rl", "ISBN:0781735149", "PMID:16551251" ]
null
[ "haematopoietic progenitor cell differentiation", "haemopoietic progenitor cell differentiation", "hemopoietic progenitor cell differentiation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030154" ]
[ "part_of GO:0030097" ]
[ "part_of" ]
[ "GO:0030097" ]
[ "GO:0030097", "GO:0030154" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002246
2,246
wound healing involved in inflammatory response
biological_process
The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.
[ "GOC:jal", "ISBN:0721601871" ]
null
[ "healing during inflammatory response", "inflammatory response wound healing" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0042060" ]
[ "part_of GO:0090594" ]
[ "part_of" ]
[ "GO:0090594" ]
[ "GO:0042060", "GO:0090594" ]
[ "GO:0042060", "part_of GO:0006954" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002247
2,247
obsolete clearance of damaged tissue involved in inflammatory response wound healing
biological_process
OBSOLETE. The series of events leading to removal of necrotic debris that contribute to an inflammatory response.
[ "GOC:jal", "ISBN:0721601871" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "clearance of damaged tissue during inflammatory response" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
3
GO:0002248
2,248
connective tissue replacement involved in inflammatory response wound healing
biological_process
The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared, as part of an inflammatory response.
[ "GOC:jal", "PMID:9639571" ]
null
[ "connective tissue replacement during inflammatory response", "fibrosis during inflammatory response", "tissue fibrosis development" ]
[ "RELATED", "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0097709" ]
[ "part_of GO:0002246" ]
[ "part_of" ]
[ "GO:0002246" ]
[ "GO:0002246", "GO:0097709" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12035\" xsd:anyURI" ]
null
null
false
true
2
GO:0002249
2,249
lymphocyte anergy
biological_process
Any process contributing to lymphocyte anergy, a state of functional inactivation.
[ "GOC:add" ]
null
[]
[]
[]
[]
[]
[ "GO:0002507" ]
[]
[]
[]
[ "GO:0002507" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002250
2,250
adaptive immune response
biological_process
An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "acquired immune response", "immune memory response" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-1280218 \"Adaptive Immune System\"", "Wikipedia:Adaptive_immune_system" ]
[ "GO:0006955" ]
[]
[]
[]
[ "GO:0006955" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002251
2,251
organ or tissue specific immune response
biological_process
An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues.
[ "GO_REF:0000022", "GOC:jal" ]
null
[ "immune response in organ or tissue" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006955" ]
[]
[]
[]
[ "GO:0006955" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002253
2,253
activation of immune response
biological_process
Any process that initiates an immune response.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002376", "GO:0050778" ]
[]
[]
[]
[ "GO:0002376", "GO:0050778" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002254
2,254
kinin cascade
biological_process
A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increas...
[ "GOC:jal", "ISBN:0721601871", "PMID:11842287", "PMID:14501145" ]
null
[]
[]
[]
[]
[]
[ "GO:0002526", "GO:0072376" ]
[]
[]
[]
[ "GO:0002526", "GO:0072376" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002255
2,255
tissue kallikrein-kinin cascade
biological_process
A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ult...
[ "GOC:add", "PMID:11842287", "PMID:14501145" ]
null
[ "glandular kallikrein-kinin cascade" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002254" ]
[]
[]
[]
[ "GO:0002254" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002256
2,256
regulation of kinin cascade
biological_process
Any process that modulates the frequency, rate, or extent of the kinin cascade.
[ "GOC:jal" ]
null
[]
[]
[]
[]
[]
[ "GO:0002673", "GO:2000257" ]
[ "regulates GO:0002254" ]
[ "regulates" ]
[ "GO:0002254" ]
[ "GO:0002254", "GO:0002673", "GO:2000257" ]
[ "GO:0065007", "regulates GO:0002254" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002257
2,257
negative regulation of kinin cascade
biological_process
Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade.
[ "GOC:jal" ]
null
[ "down regulation of kinin cascade", "down-regulation of kinin cascade", "downregulation of kinin cascade", "inhibition of kinin cascade" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0002256", "GO:0002674", "GO:2000258" ]
[ "negatively_regulates GO:0002254" ]
[ "negatively_regulates" ]
[ "GO:0002254" ]
[ "GO:0002254", "GO:0002256", "GO:0002674", "GO:2000258" ]
[ "GO:0065007", "negatively_regulates GO:0002254" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002258
2,258
positive regulation of kinin cascade
biological_process
Any process that activates or increases the frequency, rate, or extent of the kinin cascade.
[ "GOC:jal" ]
null
[ "activation of kinin cascade", "stimulation of kinin cascade", "up regulation of kinin cascade", "up-regulation of kinin cascade", "upregulation of kinin cascade" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002256", "GO:0002675", "GO:2000259" ]
[ "positively_regulates GO:0002254" ]
[ "positively_regulates" ]
[ "GO:0002254" ]
[ "GO:0002254", "GO:0002256", "GO:0002675", "GO:2000259" ]
[ "GO:0065007", "positively_regulates GO:0002254" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002259
2,259
obsolete endothelial cell activation within high endothelial venule involved in immune response
biological_process
OBSOLETE. A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "endothelial cell activation within high endothelial venule during immune response" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
3
GO:0002260
2,260
lymphocyte homeostasis
biological_process
The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.
[ "GOC:add", "PMID:15826826", "PMID:16319493", "PMID:16551252", "PMID:16551262" ]
null
[]
[]
[]
[]
[]
[ "GO:0001776" ]
[]
[]
[]
[ "GO:0001776" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002261
2,261
mucosal lymphocyte homeostasis
biological_process
The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.
[ "GOC:add", "PMID:15609020" ]
null
[]
[]
[]
[]
[]
[ "GO:0002260" ]
[]
[]
[]
[ "GO:0002260" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002262
2,262
myeloid cell homeostasis
biological_process
The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
[ "CL:0000763", "GOC:add" ]
null
[]
[]
[]
[]
[]
[ "GO:0002376", "GO:0048872" ]
[]
[]
[]
[ "GO:0002376", "GO:0048872" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0002263
2,263
cell activation involved in immune response
biological_process
A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
[ "GO_REF:0000022", "GOC:add", "ISBN:0781735149" ]
null
[ "cell activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0001775", "GO:0002252" ]
[ "part_of GO:0006955" ]
[ "part_of" ]
[ "GO:0006955" ]
[ "GO:0001775", "GO:0002252", "GO:0006955" ]
[ "GO:0001775", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002264
2,264
endothelial cell activation involved in immune response
biological_process
A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "endothelial cell activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002263", "GO:0042118" ]
[]
[]
[]
[ "GO:0002263", "GO:0042118" ]
[ "GO:0042118", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002265
2,265
astrocyte activation involved in immune response
biological_process
A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "PMID:11138785" ]
null
[ "astrocyte activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002263", "GO:0048143" ]
[]
[]
[]
[ "GO:0002263", "GO:0048143" ]
[ "GO:0048143", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002266
2,266
follicular dendritic cell activation
biological_process
A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
[ "GOC:add", "PMID:15606789" ]
null
[]
[]
[]
[]
[]
[ "GO:0001775" ]
[]
[]
[]
[ "GO:0001775" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0002267
2,267
obsolete follicular dendritic cell activation involved in immune response
biological_process
OBSOLETE. A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "PMID:15606789" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "follicular dendritic cell activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0002266", "GO:0006955" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
8
GO:0002268
2,268
follicular dendritic cell differentiation
biological_process
The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.
[ "GOC:add", "ISBN:0781735149" ]
null
[]
[]
[]
[]
[]
[ "GO:0002266", "GO:0030154" ]
[]
[]
[]
[ "GO:0002266", "GO:0030154" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0002269
2,269
leukocyte activation involved in inflammatory response
biological_process
A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "immune cell activation during inflammatory response", "leukocyte activation during inflammatory response" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0045321" ]
[ "part_of GO:0006954" ]
[ "part_of" ]
[ "GO:0006954" ]
[ "GO:0006954", "GO:0045321" ]
[ "GO:0045321", "part_of GO:0006954" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002270
2,270
plasmacytoid dendritic cell activation
biological_process
A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
[ "GOC:add", "PMID:15990333", "PMID:16174109" ]
null
[]
[]
[]
[]
[]
[ "GO:0045321" ]
[]
[]
[]
[ "GO:0045321" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0002271
2,271
obsolete plasmacytoid dendritic cell activation involved in immune response
biological_process
OBSOLETE. A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "PMID:15990333", "PMID:16174109" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "plasmacytoid dendritic cell activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
null
null
true
true
4
GO:0002272
2,272
obsolete plasmacytoid dendritic cell differentiation involved in immune response
biological_process
OBSOLETE. The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response.
[ "GOC:add", "PMID:15990333" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "plasmacytoid dendritic cell differentiation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0002273", "GO:0006955" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
5
GO:0002273
2,273
plasmacytoid dendritic cell differentiation
biological_process
The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell.
[ "GOC:add", "PMID:15990333", "PMID:16174108" ]
null
[]
[]
[]
[]
[]
[ "GO:0002270", "GO:0097028" ]
[]
[]
[]
[ "GO:0002270", "GO:0097028" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0002274
2,274
myeloid leukocyte activation
biological_process
A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "myeloid leucocyte activation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0045321" ]
[]
[]
[]
[ "GO:0045321" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002275
2,275
myeloid cell activation involved in immune response
biological_process
A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "myeloid cell activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002274", "GO:0002366" ]
[]
[]
[]
[ "GO:0002274", "GO:0002366" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002276
2,276
basophil activation involved in immune response
biological_process
A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "basophil activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002366", "GO:0045575" ]
[ "part_of GO:0002275" ]
[ "part_of" ]
[ "GO:0002275" ]
[ "GO:0002275", "GO:0002366", "GO:0045575" ]
[ "GO:0045575", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002278
2,278
eosinophil activation involved in immune response
biological_process
The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "eosinophil activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002275", "GO:0043307" ]
[]
[]
[]
[ "GO:0002275", "GO:0043307" ]
[ "GO:0043307", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0002279
2,279
mast cell activation involved in immune response
biological_process
The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "mast cell activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002275", "GO:0045576" ]
[]
[]
[]
[ "GO:0002275", "GO:0045576" ]
[ "GO:0045576", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002280
2,280
monocyte activation involved in immune response
biological_process
The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149", "PMID:16551245" ]
null
[ "monocyte activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002275", "GO:0042117" ]
[]
[]
[]
[ "GO:0002275", "GO:0042117" ]
[ "GO:0042117", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0002281
2,281
macrophage activation involved in immune response
biological_process
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "macrophage activation during immune response", "macrophage polarization involved in immune response" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0002366", "GO:0042116" ]
[ "part_of GO:0002275" ]
[ "part_of" ]
[ "GO:0002275" ]
[ "GO:0002275", "GO:0002366", "GO:0042116" ]
[ "GO:0042116", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0002282
2,282
microglial cell activation involved in immune response
biological_process
The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "microglial cell activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0001774", "GO:0002281" ]
[]
[]
[]
[ "GO:0001774", "GO:0002281" ]
[ "GO:0001774", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0002284
2,284
obsolete myeloid dendritic cell differentiation involved in immune response
biological_process
OBSOLETE. The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "myeloid dendritic cell differentiation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006955", "GO:0043011" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
2
GO:0002285
2,285
lymphocyte activation involved in immune response
biological_process
A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
[ "GOC:add", "ISBN:0781735149" ]
null
[ "lymphocyte activation during immune response" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002366", "GO:0046649" ]
[]
[]
[]
[ "GO:0002366", "GO:0046649" ]
[ "GO:0046649", "part_of GO:0006955" ]
[]
[]
[]
[]
[]
null
null
false
true
7