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GO

Dataset card Data Studio Files
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 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0070832
70,832
phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline
biological_process
The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidy...
[ "MetaCyc:PWY4FS-2" ]
null
[]
[]
[]
[]
[ "MetaCyc:PWY4FS-2" ]
[ "GO:0006656" ]
[]
[]
[]
[ "GO:0006656" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-29T03:49:14Z
false
true
8
GO:0070833
70,833
phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine
biological_process
The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl...
[ "MetaCyc:PWY4FS-3" ]
null
[]
[]
[]
[]
[ "MetaCyc:PWY4FS-3" ]
[ "GO:0006656" ]
[]
[]
[]
[ "GO:0006656" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-29T03:51:39Z
false
true
8
GO:0070834
70,834
phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine
biological_process
The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethan...
[ "MetaCyc:PWY4FS-4" ]
null
[]
[]
[]
[]
[ "MetaCyc:PWY4FS-4" ]
[ "GO:0006656" ]
[]
[]
[]
[ "GO:0006656" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-29T03:54:47Z
false
true
9
GO:0070835
70,835
chromium ion transmembrane transporter activity
molecular_function
Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.
[ "GOC:mah", "GOC:yaf" ]
null
[]
[]
[]
[]
[]
[ "GO:0022857" ]
[]
[]
[]
[ "GO:0022857" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-30T03:04:09Z
false
true
8
GO:0070836
70,836
caveola assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.
[ "GOC:BHF", "GOC:mah", "GOC:vk", "PMID:12633858" ]
null
[ "caveola formation", "caveolar biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0044854" ]
[]
[]
[]
[ "GO:0044854" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-30T04:45:54Z
false
true
7
GO:0070837
70,837
dehydroascorbic acid transport
biological_process
The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.
[ "GOC:sl" ]
null
[ "dehydroascorbate transport" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0015711", "GO:0051180" ]
[]
[]
[]
[ "GO:0015711", "GO:0051180" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-30T05:24:31Z
false
true
2
GO:0070840
70,840
dynein complex binding
molecular_function
Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
[ "GOC:bf", "GOC:BHF", "GOC:mah" ]
null
[ "dynein binding" ]
[ "RELATED" ]
[ "GO:0045502" ]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-31T01:22:47Z
false
true
3
GO:0070841
70,841
inclusion body assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form an inclusion body.
[ "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0022607" ]
[]
[]
[]
[ "GO:0022607" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-31T01:28:14Z
false
true
1
GO:0070843
70,843
misfolded protein transport
biological_process
The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
[ "GOC:BHF", "GOC:mah", "PMID:14675537" ]
null
[]
[]
[]
[]
[]
[ "GO:0006886" ]
[]
[]
[]
[ "GO:0006886" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-31T12:50:00Z
false
true
6
GO:0070844
70,844
polyubiquitinated protein transport
biological_process
The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
[ "GOC:BHF", "GOC:mah", "PMID:14675537" ]
null
[ "polyubiquitylated protein transport" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006886" ]
[]
[]
[]
[ "GO:0006886" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-31T12:51:10Z
false
true
9
GO:0070845
70,845
polyubiquitinated misfolded protein transport
biological_process
The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
[ "GOC:BHF", "GOC:mah", "PMID:14675537" ]
null
[ "misfolded polyubiquitinated protein transport", "polyubiquitylated misfolded protein transport" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0070843", "GO:0070844" ]
[]
[]
[]
[ "GO:0070843", "GO:0070844" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-31T12:52:26Z
false
true
5
GO:0070846
70,846
Hsp90 deacetylation
biological_process
The modification of an Hsp90 protein by removal of acetyl groups.
[ "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[ "gocheck_obsoletion_candidate" ]
[]
[ "GO:0006476" ]
[]
[]
[]
[ "GO:0006476" ]
[]
[]
[]
[]
[]
[]
mah
2009-07-31T12:58:47Z
false
true
9
GO:0070847
70,847
core mediator complex
cellular_component
A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of t...
[ "PMID:11454195", "PMID:16168358", "PMID:17870225" ]
null
[ "C mediator complex", "S mediator complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0090575" ]
[]
[]
[]
[ "GO:0090575" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15979\" xsd:anyURI" ]
mah
2009-08-04T02:56:11Z
false
true
2
GO:0070848
70,848
response to growth factor
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
[ "GOC:BHF", "GOC:mah" ]
null
[ "response to growth factor stimulus" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0009719" ]
[]
[]
[]
[ "GO:0009719" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-04T04:24:18Z
false
true
9
GO:0070849
70,849
response to epidermal growth factor
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
[ "GOC:BHF", "GOC:mah" ]
null
[ "response to EGF stimulus", "response to epidermal growth factor stimulus" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0070848" ]
[]
[]
[]
[ "GO:0070848" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-04T04:26:26Z
false
true
4
GO:0070850
70,850
TACC/TOG complex
cellular_component
A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with micro...
[ "GOC:mah", "GOC:vw", "PMID:19606211" ]
null
[]
[]
[]
[]
[]
[ "GO:0140535" ]
[]
[]
[]
[ "GO:0140535" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-05T03:06:08Z
false
true
2
GO:0070851
70,851
growth factor receptor binding
molecular_function
Binding to a growth factor receptor.
[ "GOC:mah", "GOC:vw" ]
null
[]
[]
[]
[]
[]
[ "GO:0005102" ]
[]
[]
[]
[ "GO:0005102" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-07T11:23:02Z
false
true
9
GO:0070852
70,852
cell body fiber
cellular_component
A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.
[ "GOC:dos", "GOC:mah" ]
null
[ "cell body fibre", "primary neurite" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0043005" ]
[]
[]
[]
[ "GO:0043005" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-11T04:38:53Z
false
true
5
GO:0070853
70,853
myosin VI binding
molecular_function
Binding to a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
[ "GOC:mah", "PMID:15473855" ]
null
[]
[]
[]
[]
[]
[ "GO:0017022" ]
[]
[]
[]
[ "GO:0017022" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-13T01:28:36Z
false
true
5
GO:0070854
70,854
myosin VI heavy chain binding
molecular_function
Binding to a heavy chain of a myosin VI complex.
[ "GOC:sart" ]
null
[]
[]
[]
[]
[]
[ "GO:0032036", "GO:0070853" ]
[]
[]
[]
[ "GO:0032036", "GO:0070853" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-13T01:44:05Z
false
true
2
GO:0070855
70,855
myosin VI head/neck binding
molecular_function
Binding to the head/neck region of a myosin VI heavy chain.
[ "GOC:sart" ]
null
[]
[]
[]
[]
[]
[ "GO:0032028", "GO:0070854" ]
[]
[]
[]
[ "GO:0032028", "GO:0070854" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-13T01:45:08Z
false
true
3
GO:0070856
70,856
myosin VI light chain binding
molecular_function
Binding to a light chain of a myosin VI complex.
[ "GOC:sart" ]
null
[]
[]
[]
[]
[]
[ "GO:0032027", "GO:0070853" ]
[]
[]
[]
[ "GO:0032027", "GO:0070853" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-13T01:46:13Z
false
true
5
GO:0070857
70,857
regulation of bile acid biosynthetic process
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
[ "GOC:BHF", "GOC:mah" ]
null
[ "regulation of bile acid anabolism", "regulation of bile acid biosynthesis", "regulation of bile acid formation", "regulation of bile acid synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0010565", "GO:0050810", "GO:0062012" ]
[ "regulates GO:0006699" ]
[ "regulates" ]
[ "GO:0006699" ]
[ "GO:0006699", "GO:0010565", "GO:0050810", "GO:0062012" ]
[ "GO:0065007", "regulates GO:0006699" ]
[]
[]
[]
[]
[]
mah
2009-08-14T03:09:02Z
false
true
9
GO:0070858
70,858
negative regulation of bile acid biosynthetic process
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
[ "GOC:BHF", "GOC:mah" ]
null
[ "down regulation of bile acid biosynthetic process", "down-regulation of bile acid biosynthetic process", "downregulation of bile acid biosynthetic process", "inhibition of bile acid biosynthetic process", "negative regulation of bile acid anabolism", "negative regulation of bile acid biosynthesis", "ne...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0010894", "GO:0062014", "GO:0070857" ]
[ "negatively_regulates GO:0006699" ]
[ "negatively_regulates" ]
[ "GO:0006699" ]
[ "GO:0006699", "GO:0010894", "GO:0062014", "GO:0070857" ]
[ "GO:0065007", "negatively_regulates GO:0006699" ]
[]
[]
[]
[]
[]
mah
2009-08-14T03:16:40Z
false
true
8
GO:0070859
70,859
positive regulation of bile acid biosynthetic process
biological_process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
[ "GOC:BHF", "GOC:mah" ]
null
[ "activation of bile acid biosynthetic process", "positive regulation of bile acid anabolism", "positive regulation of bile acid biosynthesis", "positive regulation of bile acid formation", "positive regulation of bile acid synthesis", "stimulation of bile acid biosynthetic process", "up regulation of bi...
[ "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0010893", "GO:0062013", "GO:0070857" ]
[ "positively_regulates GO:0006699" ]
[ "positively_regulates" ]
[ "GO:0006699" ]
[ "GO:0006699", "GO:0010893", "GO:0062013", "GO:0070857" ]
[ "GO:0065007", "positively_regulates GO:0006699" ]
[]
[]
[]
[]
[]
mah
2009-08-14T03:22:58Z
false
true
3
GO:0070860
70,860
RNA polymerase I core factor complex
cellular_component
A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.
[ "PMID:8702872" ]
Note that, although this complex can be considered analogous to the mammalian transcription factor SL complex, the core factor complex does not include TBP, whereas SL1 does.
[]
[]
[]
[]
[]
[ "GO:0000120" ]
[]
[]
[]
[ "GO:0000120" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-14T05:00:44Z
false
true
9
GO:0070861
70,861
regulation of protein exit from endoplasmic reticulum
biological_process
Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
[ "GOC:mah" ]
null
[ "regulation of protein exit from ER", "regulation of protein export from endoplasmic reticulum", "regulation of protein export from ER" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0033157" ]
[ "regulates GO:0032527" ]
[ "regulates" ]
[ "GO:0032527" ]
[ "GO:0032527", "GO:0033157" ]
[ "GO:0065007", "regulates GO:0032527" ]
[]
[]
[]
[]
[]
mah
2009-08-17T03:39:18Z
false
true
6
GO:0070862
70,862
negative regulation of protein exit from endoplasmic reticulum
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
[ "GOC:mah" ]
null
[ "down regulation of protein exit from endoplasmic reticulum", "down-regulation of protein exit from endoplasmic reticulum", "downregulation of protein exit from endoplasmic reticulum", "inhibition of protein exit from endoplasmic reticulum", "negative regulation of protein exit from ER", "negative regulat...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0070861", "GO:0090317" ]
[ "negatively_regulates GO:0032527" ]
[ "negatively_regulates" ]
[ "GO:0032527" ]
[ "GO:0032527", "GO:0070861", "GO:0090317" ]
[ "GO:0065007", "negatively_regulates GO:0032527" ]
[]
[]
[]
[]
[]
mah
2009-08-17T03:45:56Z
false
true
8
GO:0070863
70,863
positive regulation of protein exit from endoplasmic reticulum
biological_process
Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
[ "GOC:mah" ]
null
[ "activation of protein exit from endoplasmic reticulum", "positive regulation of protein exit from ER", "positive regulation of protein export from endoplasmic reticulum", "positive regulation of protein export from ER", "stimulation of protein exit from endoplasmic reticulum", "up regulation of protein e...
[ "NARROW", "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0070861", "GO:0090316" ]
[ "positively_regulates GO:0032527" ]
[ "positively_regulates" ]
[ "GO:0032527" ]
[ "GO:0032527", "GO:0070861", "GO:0090316" ]
[ "GO:0065007", "positively_regulates GO:0032527" ]
[]
[]
[]
[]
[]
mah
2009-08-17T03:50:04Z
false
true
4
GO:0070864
70,864
sperm individualization complex
cellular_component
A cellular structure that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus...
[ "GOC:sart", "PMID:10588662", "PMID:9550716" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26172\" xsd:anyURI" ]
mah
2009-08-19T01:25:33Z
false
true
2
GO:0070865
70,865
investment cone
cellular_component
A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.
[ "GOC:sart", "PMID:15829565", "PMID:9550716" ]
null
[ "F-actin cone" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005856", "part_of GO:0070864" ]
[ "part_of", "part_of" ]
[ "GO:0005856", "GO:0070864" ]
[ "GO:0005856", "GO:0070864", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-19T01:29:33Z
false
true
7
GO:0070867
70,867
mating projection tip membrane
cellular_component
The portion of the plasma membrane surrounding a mating projection tip.
[ "GOC:mah" ]
null
[ "mating projection membrane fusion domain", "shmoo tip membrane" ]
[ "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0031520" ]
[ "part_of GO:0043332" ]
[ "part_of" ]
[ "GO:0043332" ]
[ "GO:0031520", "GO:0043332" ]
[ "GO:0098590", "part_of GO:0043332" ]
[]
[]
[]
[]
[]
mah
2009-08-19T04:05:58Z
false
true
9
GO:0070868
70,868
obsolete heterochromatin organization involved in chromatin silencing
biological_process
OBSOLETE. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing.
[ "GOC:mah" ]
This term was obsoleted because it was not clearly defined, and used incorrectly.
[ "heterochromatin organisation involved in chromatin silencing" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22046\" xsd:anyURI" ]
mah
2009-08-20T12:45:52Z
true
true
3
GO:0070871
70,871
obsolete cell wall organization involved in conjugation with cellular fusion
biological_process
OBSOLETE. A process of cell wall organization that contributes to conjugation with cellular fusion.
[ "GOC:mah" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "cell wall organisation involved in conjugation with cellular fusion" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
mah
2009-08-20T02:23:19Z
true
true
1
GO:0070873
70,873
regulation of glycogen metabolic process
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
[ "GOC:mah" ]
null
[ "regulation of glycogen metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032881", "GO:0043467" ]
[ "regulates GO:0005977" ]
[ "regulates" ]
[ "GO:0005977" ]
[ "GO:0005977", "GO:0032881", "GO:0043467" ]
[ "GO:0065007", "regulates GO:0005977" ]
[]
[]
[]
[]
[]
mah
2009-08-20T02:44:53Z
false
true
9
GO:0070875
70,875
positive regulation of glycogen metabolic process
biological_process
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
[ "GOC:mah" ]
null
[ "positive regulation of glycogen metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0010604", "GO:0010907", "GO:0070873" ]
[ "positively_regulates GO:0005977" ]
[ "positively_regulates" ]
[ "GO:0005977" ]
[ "GO:0005977", "GO:0010604", "GO:0010907", "GO:0070873" ]
[ "GO:0065007", "positively_regulates GO:0005977" ]
[]
[]
[]
[]
[]
mah
2009-08-20T02:53:55Z
false
true
8
GO:0070876
70,876
SOSS complex
cellular_component
A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.
[ "PMID:19683501" ]
null
[]
[]
[]
[]
[]
[ "GO:0140513" ]
[]
[]
[]
[ "GO:0140513" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-20T03:30:48Z
false
true
7
GO:0070877
70,877
microprocessor complex
cellular_component
A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bou...
[ "PMID:16963499", "PMID:17159994" ]
null
[]
[]
[]
[]
[]
[ "GO:0140513", "GO:1903095" ]
[]
[]
[]
[ "GO:0140513", "GO:1903095" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-20T03:56:26Z
false
true
6
GO:0070878
70,878
primary miRNA binding
molecular_function
Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.
[ "GOC:sl", "PMID:15531877", "PMID:15574589" ]
null
[ "pri-miRNA binding", "primary microRNA binding" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0003723" ]
[]
[]
[]
[ "GO:0003723" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-20T04:11:36Z
false
true
3
GO:0070881
70,881
regulation of proline transport
biological_process
Any process that modulates the frequency, rate or extent of proline transport.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0032890", "GO:0051955" ]
[ "regulates GO:0015824" ]
[ "regulates" ]
[ "GO:0015824" ]
[ "GO:0015824", "GO:0032890", "GO:0051955" ]
[ "GO:0065007", "regulates GO:0015824" ]
[]
[]
[]
[]
[]
mah
2009-08-21T04:48:34Z
false
true
6
GO:0070883
70,883
pre-miRNA binding
molecular_function
Binding to a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.
[ "PMID:18951094" ]
null
[ "pre-microRNA binding", "precursor microRNA binding" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0003723" ]
[]
[]
[]
[ "GO:0003723" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-24T04:36:24Z
false
true
4
GO:0070884
70,884
regulation of calcineurin-NFAT signaling cascade
biological_process
Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.
[ "GOC:ai" ]
null
[ "NFAT protein import into nucleus", "regulation of calcineurin-NFAT signaling pathway", "regulation of calcineurin-NFAT signalling cascade", "regulation of NFAT protein import into nucleus" ]
[ "NARROW", "RELATED", "EXACT", "NARROW" ]
[ "GO:0051531", "GO:0051532" ]
[]
[]
[ "GO:0106056" ]
[ "regulates GO:0033173" ]
[ "regulates" ]
[ "GO:0033173" ]
[ "GO:0033173", "GO:0106056" ]
[ "GO:0065007", "regulates GO:0033173" ]
[]
[]
[]
[]
[]
mah
2009-08-26T03:25:30Z
false
true
9
GO:0070885
70,885
negative regulation of calcineurin-NFAT signaling cascade
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.
[ "GOC:mah" ]
null
[ "down regulation of calcineurin-NFAT signaling cascade", "down-regulation of calcineurin-NFAT signaling cascade", "downregulation of calcineurin-NFAT signaling cascade", "inhibition of calcineurin-NFAT signaling cascade", "inhibition of NFAT protein import into nucleus", "negative regulation of calcineuri...
[ "EXACT", "EXACT", "EXACT", "NARROW", "NARROW", "RELATED", "EXACT", "NARROW", "NARROW" ]
[ "GO:0051534" ]
[]
[]
[ "GO:0070884", "GO:0106057" ]
[ "negatively_regulates GO:0033173" ]
[ "negatively_regulates" ]
[ "GO:0033173" ]
[ "GO:0033173", "GO:0070884", "GO:0106057" ]
[ "GO:0065007", "negatively_regulates GO:0033173" ]
[]
[]
[]
[]
[]
mah
2009-08-26T03:29:33Z
false
true
8
GO:0070886
70,886
positive regulation of calcineurin-NFAT signaling cascade
biological_process
Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.
[ "GOC:mah" ]
null
[ "activation of calcineurin-NFAT signaling cascade", "positive regulation of calcineurin-NFAT signaling pathway", "positive regulation of calcineurin-NFAT signalling cascade", "positive regulation of NFAT protein import into nucleus", "stimulation of calcineurin-NFAT signaling cascade", "up regulation of c...
[ "NARROW", "RELATED", "EXACT", "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[ "GO:0051533" ]
[]
[]
[ "GO:0070884", "GO:0106058" ]
[ "positively_regulates GO:0033173" ]
[ "positively_regulates" ]
[ "GO:0033173" ]
[ "GO:0033173", "GO:0070884", "GO:0106058" ]
[ "GO:0065007", "positively_regulates GO:0033173" ]
[]
[]
[]
[]
[]
mah
2009-08-26T03:37:10Z
false
true
3
GO:0070887
70,887
cellular response to chemical stimulus
biological_process
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
[ "GOC:mah" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
[]
[]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0042221", "GO:0051716" ]
[]
[]
[]
[ "GO:0042221", "GO:0051716" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-27T04:41:45Z
false
true
8
GO:0070888
70,888
E-box binding
molecular_function
Binding to an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.
[ "GOC:BHF", "GOC:vk", "PMID:11812799" ]
null
[ "E-box promoter binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000978" ]
[]
[]
[]
[ "GO:0000978" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-28T10:37:01Z
false
true
1
GO:0070889
70,889
platelet alpha granule organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets.
[ "GOC:rph", "PMID:16123220" ]
null
[ "platelet alpha granule organisation", "platelet alpha granule organization and biogenesis", "platelet alpha-granule organization" ]
[ "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0033363" ]
[]
[]
[]
[ "GO:0033363" ]
[]
[]
[]
[]
[]
[]
mah
2009-08-28T10:43:31Z
false
true
5
GO:0070891
70,891
lipoteichoic acid binding
molecular_function
Binding to lipoteichoic acid.
[ "GOC:add", "PMID:14665680" ]
null
[]
[]
[]
[]
[]
[ "GO:0097367" ]
[]
[]
[]
[ "GO:0097367" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-01T02:56:36Z
false
true
4
GO:0070892
70,892
lipoteichoic acid immune receptor activity
molecular_function
Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response.
[ "GOC:add", "PMID:14665680" ]
null
[ "lipoteichoic acid receptor activity" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0038187" ]
[ "has_part GO:0070891" ]
[ "has_part" ]
[ "GO:0070891" ]
[ "GO:0038187", "GO:0070891" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-01T02:59:24Z
false
true
8
GO:0070893
70,893
obsolete transposon integration
biological_process
OBSOLETE. Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome.
[ "GOC:jp", "PMID:10882723" ]
This term was obsoleted because it represents a readout.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006313", "GO:0032197" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24560\" xsd:anyURI" ]
mah
2009-09-01T04:08:19Z
true
true
2
GO:0070894
70,894
obsolete regulation of transposon integration
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.
[ "GOC:mah" ]
This term was obsoleted because it represents a readout.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006313", "GO:0032197" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24560\" xsd:anyURI" ]
mah
2009-09-01T04:14:09Z
true
true
1
GO:0070895
70,895
obsolete negative regulation of transposon integration
biological_process
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.
[ "GOC:mah" ]
This term was obsoleted because it represents a readout.
[ "down regulation of transposon integration", "down-regulation of transposon integration", "downregulation of transposon integration", "inhibition of transposon integration" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006313", "GO:0032197" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24560\" xsd:anyURI" ]
mah
2009-09-01T04:20:36Z
true
true
5
GO:0070896
70,896
obsolete positive regulation of transposon integration
biological_process
OBSOLETE. Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.
[ "GOC:mah" ]
This term was obsoleted because it represents a readout.
[ "activation of transposon integration", "stimulation of transposon integration", "up regulation of transposon integration", "up-regulation of transposon integration", "upregulation of transposon integration" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006313", "GO:0032197" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24560\" xsd:anyURI" ]
mah
2009-09-01T04:25:06Z
true
true
6
GO:0070897
70,897
transcription preinitiation complex assembly
biological_process
The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC). The PIC engages the RNA polymerase on its DNA template strand and sparks polymerization of the first few RNA nucleotid...
[ "GOC:txnOH" ]
null
[ "bacterial-type RNA polymerase preinitiation complex assembly", "bacterial-type RNA polymerase transcription PIC formation", "bacterial-type RNA polymerase transcriptional preinitiation complex formation", "DNA-dependent transcriptional preinitiation complex assembly", "DNA-templated transcriptional preinit...
[ "NARROW", "NARROW", "NARROW", "EXACT", "EXACT", "BROAD", "BROAD", "BROAD" ]
[ "GO:0001126" ]
[]
[]
[ "GO:0065004" ]
[ "part_of GO:0006352" ]
[ "part_of" ]
[ "GO:0006352" ]
[ "GO:0006352", "GO:0065004" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25954\" xsd:anyURI" ]
mah
2009-09-01T04:33:47Z
false
true
1
GO:0070898
70,898
RNA polymerase III preinitiation complex assembly
biological_process
The formation of a large multiprotein-DNA complex that self-assembles on a tRNA gene through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC), (which includes BDP1, BRF1, TBP, TFIIIC in human). The PIC engages RNA polymerase III on its DNA template strand and spa...
[ "GOC:txnOH", "PMID:11387215", "PMID:12381659" ]
null
[ "RNA polymerase III hybrid type promoter transcriptional preinitiation complex assembly", "RNA polymerase III transcription PIC biosynthesis", "RNA polymerase III transcription PIC formation", "RNA polymerase III transcriptional preinitiation complex assembly", "RNA polymerase III transcriptional preinitiat...
[ "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "NARROW", "NARROW", "NARROW" ]
[ "GO:0000999", "GO:0001020", "GO:0001021", "GO:0001043" ]
[]
[]
[ "GO:0070897" ]
[ "part_of GO:0006384" ]
[ "part_of" ]
[ "GO:0006384" ]
[ "GO:0006384", "GO:0070897" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25954\" xsd:anyURI" ]
mah
2010-08-19T04:16:04Z
false
true
2
GO:0070899
70,899
mitochondrial tRNA wobble uridine modification
biological_process
The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified.
[ "GOC:mah", "GOC:mcc" ]
null
[]
[]
[]
[]
[]
[ "GO:0002098", "GO:0070900" ]
[]
[]
[]
[ "GO:0002098", "GO:0070900" ]
[ "GO:0002098", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
mah
2009-09-02T03:14:13Z
false
true
9
GO:0070900
70,900
mitochondrial tRNA modification
biological_process
The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.
[ "GOC:mah", "GOC:mcc" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-6787450 \"tRNA modification in the mitochondrion\"" ]
[ "GO:0006400", "GO:0090646", "GO:1900864" ]
[]
[]
[]
[ "GO:0006400", "GO:0090646", "GO:1900864" ]
[ "GO:0006400", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
mah
2009-09-02T03:16:53Z
false
true
5
GO:0070901
70,901
mitochondrial tRNA methylation
biological_process
The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.
[ "GOC:mah", "GOC:mcc" ]
null
[]
[]
[]
[]
[]
[ "GO:0030488", "GO:0070900" ]
[]
[]
[]
[ "GO:0030488", "GO:0070900" ]
[ "GO:0030488", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
mah
2009-09-02T04:08:00Z
false
true
1
GO:0070903
70,903
mitochondrial tRNA thio-modification
biological_process
The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.
[ "GOC:mah", "GOC:mcc" ]
null
[]
[]
[]
[]
[]
[ "GO:0034227", "GO:0070900" ]
[]
[]
[]
[ "GO:0034227", "GO:0070900" ]
[ "GO:0034227", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
mah
2009-09-02T04:11:17Z
false
true
7
GO:0070904
70,904
obsolete transepithelial L-ascorbic acid transport
biological_process
OBSOLETE. The directed movement of L-ascorbic acid from one side of an epithelium to the other.
[ "GOC:mah", "GOC:yaf" ]
This term was obsoleted because it represents a combination of a process and an anatomical entity.
[ "transepithelial L-ascorbate transport", "transepithelial vitamin C transport" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0015882", "GO:0070633" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20569\" xsd:anyURI" ]
mah
2009-09-03T02:21:25Z
true
true
1
GO:0070905
70,905
serine binding
molecular_function
Binding to 2-amino-3-hydroxypropanoic acid.
[ "GOC:rph" ]
null
[ "Ser binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0016597", "GO:0031406", "GO:0043169" ]
[]
[]
[]
[ "GO:0016597", "GO:0031406", "GO:0043169" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-04T03:28:29Z
false
true
3
GO:0070906
70,906
aspartate:alanine antiporter activity
molecular_function
Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out).
[ "GOC:dh" ]
null
[ "aspartate-alanine antiporter activity", "aspartate/alanine antiporter activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "RHEA:33139" ]
[ "GO:0005310", "GO:0015297", "GO:0015556", "GO:0022858" ]
[]
[]
[]
[ "GO:0005310", "GO:0015297", "GO:0015556", "GO:0022858" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:33139", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
mah
2009-09-04T03:44:15Z
false
true
7
GO:0070908
70,908
tyrosine:tyramine antiporter activity
molecular_function
Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out).
[ "GOC:dh" ]
null
[ "tyrosine-tyramine antiporter activity", "tyrosine/tyramine antiporter activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0005302", "GO:0008504", "GO:0015297" ]
[]
[]
[]
[ "GO:0005302", "GO:0008504", "GO:0015297" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-04T03:49:45Z
false
true
1
GO:0070909
70,909
glutamate:gamma-aminobutyric acid antiporter activity
molecular_function
Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out).
[ "GOC:dh" ]
null
[ "glutamate-gamma-aminobutyric acid antiporter activity", "glutamate/gamma-aminobutyric acid antiporter activity", "glutamate: GABA antiporter activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0015185", "GO:0015297", "GO:0015355" ]
[]
[]
[]
[ "GO:0015185", "GO:0015297", "GO:0015355" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-04T03:51:32Z
false
true
6
GO:0070910
70,910
obsolete cell wall macromolecule catabolic process involved in cell wall disassembly
biological_process
OBSOLETE. The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.
[ "GOC:mah" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
mah
2009-09-09T02:40:57Z
true
true
9
GO:0070911
70,911
global genome nucleotide-excision repair
biological_process
The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.
[ "PMID:10197977", "PMID:18794354" ]
null
[ "GG-NER", "GGR", "global genome NER", "global genomic nucleotide-excision repair", "global genomic repair" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-5696399 \"Global Genome Nucleotide Excision Repair (GG-NER)\"" ]
[ "GO:0006289" ]
[]
[]
[]
[ "GO:0006289" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-09T03:13:11Z
false
true
6
GO:0070912
70,912
Ddb1-Ckn1 complex
cellular_component
A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.
[ "PMID:18794354" ]
null
[]
[]
[]
[]
[]
[ "GO:0000109" ]
[]
[]
[]
[ "GO:0000109" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-09T03:41:04Z
false
true
3
GO:0070913
70,913
Ddb1-Wdr21 complex
cellular_component
A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.
[ "PMID:18794354" ]
null
[]
[]
[]
[]
[]
[ "GO:0000109" ]
[]
[]
[]
[ "GO:0000109" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-09T03:47:54Z
false
true
5
GO:0070915
70,915
lysophosphatidic acid receptor activity
molecular_function
Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.
[ "GOC:bf", "GOC:mah", "PMID:15755723" ]
null
[ "LPA receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0045125" ]
[ "has_part GO:0035727" ]
[ "has_part" ]
[ "GO:0035727" ]
[ "GO:0035727", "GO:0045125" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-10T05:05:13Z
false
true
9
GO:0070916
70,916
inositol phosphoceramide synthase complex
cellular_component
A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).
[ "GOC:mah", "PMID:19726565" ]
null
[ "IPC synthase complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:1990234" ]
[ "part_of GO:0005794" ]
[ "part_of" ]
[ "GO:0005794" ]
[ "GO:0005794", "GO:1990234" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-10T05:23:21Z
false
true
1
GO:0070917
70,917
inositol phosphoceramide synthase regulator activity
molecular_function
Binds to and modulates the activity of inositol phosphoceramide synthase.
[ "GOC:mah" ]
See also the molecular function term 'histone acetyltransferase activity ; GO:0004402'.
[ "IPC synthase regulator activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030234" ]
[ "regulates GO:0045140" ]
[ "regulates" ]
[ "GO:0045140" ]
[ "GO:0030234", "GO:0045140" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-10T05:27:06Z
false
true
2
GO:0070918
70,918
regulatory ncRNA processing
biological_process
A process leading to the generation of a functional regulatory non-coding RNA.
[ "GOC:mah", "PMID:15196465", "PMID:19239886" ]
null
[ "gene silencing by RNA, production of guide RNA", "gene silencing by RNA, production of small RNA", "primary sncRNA processing", "production of small RNA involved in gene silencing by RNA", "small regulatory ncRNA maturation", "small regulatory ncRNA processing", "sncRNA processing", "sncRNA productio...
[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW" ]
[ "GO:0031051" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0006396" ]
[ "part_of GO:0031047" ]
[ "part_of" ]
[ "GO:0031047" ]
[ "GO:0006396", "GO:0031047" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19303\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23081\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24199\" xsd:anyURI" ]
mah
2009-09-11T03:32:19Z
false
true
6
GO:0070920
70,920
regulation of regulatory ncRNA processing
biological_process
Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing.
[ "GOC:mah" ]
null
[ "regulation of gene silencing by RNA, production of guide RNA", "regulation of gene silencing by RNA, production of small RNA", "regulation of production of small RNA involved in gene silencing by RNA" ]
[ "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0060966", "GO:0080090" ]
[ "regulates GO:0070918" ]
[ "regulates" ]
[ "GO:0070918" ]
[ "GO:0060966", "GO:0070918", "GO:0080090" ]
[ "GO:0065007", "regulates GO:0070918" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25084\" xsd:anyURI" ]
mah
2009-09-11T03:41:59Z
false
true
7
GO:0070921
70,921
regulation of siRNA processing
biological_process
Any process that modulates the frequency, rate or extent of siRNA processing.
[ "GOC:mah" ]
null
[ "regulation of chromatin silencing by small RNA, production of siRNA", "regulation of production of siRNA involved in chromatin silencing by small RNA", "regulation of production of siRNA involved in gene silencing by small RNA", "regulation of production of siRNA involved in post-transcriptional gene silenci...
[ "EXACT", "EXACT", "RELATED", "RELATED", "RELATED", "EXACT", "EXACT", "RELATED" ]
[ "GO:0090065" ]
[]
[]
[ "GO:0070920" ]
[ "regulates GO:0030422" ]
[ "regulates" ]
[ "GO:0030422" ]
[ "GO:0030422", "GO:0070920" ]
[ "GO:0065007", "regulates GO:0030422" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19303\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22470\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25084\" xsd:anyURI" ]
tb
2009-08-12T11:41:09Z
false
true
1
GO:0070922
70,922
RISC complex assembly
biological_process
The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pa...
[ "PMID:14512631", "PMID:14744438", "PMID:19239886", "PMID:22233755", "PMID:27184117" ]
null
[ "gene silencing by RNA, small RNA loading onto RISC", "miRISC assembly", "miRNA loading onto RISC", "RISC assembly", "siRNA loading onto RISC involved in gene silencing by small RNA", "siRNA loading onto RISC involved in RNA interference", "small RNA loading onto RISC" ]
[ "RELATED", "BROAD", "NARROW", "RELATED", "NARROW", "NARROW", "RELATED" ]
[ "GO:0035087", "GO:0035280", "GO:0070923" ]
[]
[]
[ "GO:0022618" ]
[ "part_of GO:0031047" ]
[ "part_of" ]
[ "GO:0031047" ]
[ "GO:0022618", "GO:0031047" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22653\" xsd:anyURI" ]
mah
2009-09-11T03:57:38Z
false
true
5
GO:0070925
70,925
organelle assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
[ "GOC:mah" ]
null
[]
[]
[]
[ "gocheck_do_not_annotate", "goslim_yeast" ]
[]
[ "GO:0006996", "GO:0022607" ]
[]
[]
[]
[ "GO:0006996", "GO:0022607" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-15T03:00:51Z
false
true
1
GO:0070926
70,926
obsolete regulation of ATP:ADP antiporter activity
biological_process
OBSOLETE. Any process that modulates the activity of an ATP:ADP antiporter.
[ "GOC:BHF", "GOC:mah" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]
mah
2009-09-16T02:56:35Z
true
true
4
GO:0070927
70,927
obsolete negative regulation of ATP:ADP antiporter activity
biological_process
OBSOLETE. Any process that stops or reduces the activity of an ATP:ADP antiporter.
[ "GOC:BHF", "GOC:mah" ]
This term was obsoleted because it represents a molecular function.
[ "down regulation of ATP:ADP antiporter activity", "down-regulation of ATP:ADP antiporter activity", "downregulation of ATP:ADP antiporter activity", "inhibition of ATP:ADP antiporter activity" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]
mah
2009-09-16T02:58:02Z
true
true
2
GO:0070928
70,928
obsolete regulation of mRNA stability, ncRNA-mediated
biological_process
OBSOLETE. Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
[ "GOC:jh2" ]
This term was obsoleted because it represents the same process as regulatory ncRNA-mediated post-transcriptional gene silencing ; GO:0035194.
[ "ncRNA-mediated regulation of mRNA stability", "regulation of mRNA stability, non-coding RNA-mediated" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0035194" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25425\" xsd:anyURI" ]
mah
2009-09-16T03:26:21Z
true
true
7
GO:0070929
70,929
trans-translation
biological_process
A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.
[ "GOC:jh2", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0006414" ]
[]
[]
[]
[ "GO:0006414" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-16T04:06:12Z
false
true
7
GO:0070930
70,930
trans-translation-dependent protein tagging
biological_process
A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.
[ "PMID:11395451", "PMID:35264790" ]
Note that this term is not a child of 'co-translational protein modification process ; GO:0043686' because co-translational protein modification implies modification of a previously incorporated amino acid in a nascent chain, rather than addition of new sequence to the C-terminus.
[ "co-translational protein tagging", "cotranslational protein tagging", "protein modification by trans-translation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0072344" ]
[ "has_part GO:0070929" ]
[ "has_part" ]
[ "GO:0070929" ]
[ "GO:0070929", "GO:0072344" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/8059\" xsd:anyURI" ]
mah
2009-09-16T04:10:49Z
false
true
4
GO:0070931
70,931
Golgi-associated vesicle lumen
cellular_component
The volume enclosed by the membrane of a Golgi-associated vesicle.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0060205" ]
[ "part_of GO:0005794", "part_of GO:0005798" ]
[ "part_of", "part_of" ]
[ "GO:0005794", "GO:0005798" ]
[ "GO:0005794", "GO:0005798", "GO:0060205" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-16T04:26:50Z
false
true
8
GO:0070932
70,932
obsolete histone H3 deacetylation
biological_process
OBSOLETE. The modification of histone H3 by the removal of one or more acetyl groups.
[ "GOC:BHF", "GOC:rl" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
mah
2009-09-16T04:50:55Z
true
true
7
GO:0070933
70,933
obsolete histone H4 deacetylation
biological_process
OBSOLETE. The modification of histone H4 by the removal of one or more acetyl groups.
[ "GOC:BHF", "GOC:rl" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]
mah
2009-09-16T04:53:06Z
true
true
7
GO:0070934
70,934
CRD-mediated mRNA stabilization
biological_process
An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).
[ "GOC:mah", "PMID:19029303" ]
null
[ "coding region determinant-mediated mRNA stabilization" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0048255" ]
[]
[]
[]
[ "GO:0048255" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-21T02:57:06Z
false
true
7
GO:0070935
70,935
3'-UTR-mediated mRNA stabilization
biological_process
An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
[ "GOC:mah", "PMID:19029303" ]
null
[ "3'-untranslated region-mediated mRNA stabilization" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0048255" ]
[]
[]
[]
[ "GO:0048255" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-21T03:08:20Z
false
true
4
GO:0070936
70,936
protein K48-linked ubiquitination
biological_process
A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
[ "GOC:cvs", "PMID:15556404" ]
null
[ "protein K48-linked polyubiquitination" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000209" ]
[]
[]
[]
[ "GO:0000209" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-21T03:25:27Z
false
true
1
GO:0070937
70,937
CRD-mediated mRNA stability complex
cellular_component
A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.
[ "GOC:mah", "PMID:19029303" ]
See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'.
[ "coding-region determinant of instability-mediated mRNA stability complex", "coding-region instability determinant -mediated mRNA stability complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0140535" ]
[]
[]
[]
[ "GO:0140535" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-22T02:00:22Z
false
true
1
GO:0070938
70,938
contractile ring
cellular_component
A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.
[ "GOC:mah", "ISBN:0123645859", "ISBN:0792354923", "PMID:10791428", "PMID:17913889" ]
null
[ "constriction ring", "cytokinetic ring" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-22T02:41:32Z
false
true
9
GO:0070941
70,941
eisosome assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The ...
[ "GOC:al", "GOC:jp", "GOC:mah", "PMID:19564405" ]
null
[]
[]
[]
[]
[]
[ "GO:0022607" ]
[]
[]
[]
[ "GO:0022607" ]
[]
[]
[]
[]
[]
[]
mah
2009-09-30T02:49:30Z
false
true
1
GO:0070942
70,942
neutrophil mediated cytotoxicity
biological_process
The directed killing of a target cell by a neutrophil.
[ "GOC:add", "ISBN:0781765196" ]
null
[ "neutrophil mediated cell killing" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001909", "GO:0002446" ]
[]
[]
[]
[ "GO:0001909", "GO:0002446" ]
[]
[]
[]
[]
[]
[]
mah
2009-10-01T01:49:30Z
false
true
3
GO:0070943
70,943
neutrophil-mediated killing of symbiont cell
biological_process
The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
[ "GOC:add", "ISBN:0781765196" ]
null
[ "neutrophil mediated killing of symbiont cell" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0031640", "GO:0070942" ]
[]
[]
[]
[ "GO:0031640", "GO:0070942" ]
[]
[]
[]
[]
[]
[]
mah
2009-10-01T01:52:03Z
false
true
2
GO:0070944
70,944
neutrophil-mediated killing of bacterium
biological_process
The directed killing of a bacterium by a neutrophil.
[ "GOC:add", "ISBN:0781765196" ]
null
[ "neutrophil mediated killing of bacterium" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070943" ]
[ "part_of GO:0042742" ]
[ "part_of" ]
[ "GO:0042742" ]
[ "GO:0042742", "GO:0070943" ]
[]
[]
[]
[]
[]
[]
mah
2009-10-01T01:55:56Z
false
true
4
GO:0070945
70,945
neutrophil-mediated killing of gram-negative bacterium
biological_process
The directed killing of a gram-negative bacterium by a neutrophil.
[ "GOC:add", "ISBN:0781765196" ]
null
[ "neutrophil mediated killing of gram-negative bacterium" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070944" ]
[ "part_of GO:0050829" ]
[ "part_of" ]
[ "GO:0050829" ]
[ "GO:0050829", "GO:0070944" ]
[]
[]
[]
[]
[]
[]
mah
2009-10-01T01:59:12Z
false
true
3
GO:0070946
70,946
neutrophil-mediated killing of gram-positive bacterium
biological_process
The directed killing of a gram-positive bacterium by a neutrophil.
[ "GOC:add", "ISBN:0781765196" ]
null
[ "neutrophil mediated killing of gram-positive bacterium" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070944" ]
[ "part_of GO:0050830" ]
[ "part_of" ]
[ "GO:0050830" ]
[ "GO:0050830", "GO:0070944" ]
[]
[]
[]
[]
[]
[]
mah
2009-10-01T02:04:15Z
false
true
5
GO:0070947
70,947
neutrophil-mediated killing of fungus
biological_process
The directed killing of a fungal cell by a neutrophil.
[ "GOC:add", "ISBN:0781765196" ]
null
[ "neutrophil mediated killing of fungus" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070943" ]
[ "part_of GO:0050832" ]
[ "part_of" ]
[ "GO:0050832" ]
[ "GO:0050832", "GO:0070943" ]
[]
[]
[]
[]
[]
[]
mah
2009-10-01T02:07:44Z
false
true
9
GO:0070948
70,948
regulation of neutrophil mediated cytotoxicity
biological_process
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.
[ "GOC:add", "GOC:mah" ]
null
[ "regulation of neutrophil mediated cell killing" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0001910", "GO:0002886" ]
[ "regulates GO:0070942" ]
[ "regulates" ]
[ "GO:0070942" ]
[ "GO:0001910", "GO:0002886", "GO:0070942" ]
[ "GO:0065007", "regulates GO:0070942" ]
[]
[]
[]
[]
[]
mah
2009-10-01T02:14:36Z
false
true
9
GO:0070949
70,949
regulation of neutrophil mediated killing of symbiont cell
biological_process
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.
[ "GOC:add", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0043903", "GO:0051709", "GO:0070948" ]
[ "regulates GO:0070943" ]
[ "regulates" ]
[ "GO:0070943" ]
[ "GO:0043903", "GO:0051709", "GO:0070943", "GO:0070948" ]
[ "GO:0065007", "regulates GO:0070943" ]
[]
[]
[]
[]
[]
mah
2009-10-01T02:14:36Z
false
true
2
GO:0070951
70,951
regulation of neutrophil mediated killing of gram-negative bacterium
biological_process
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.
[ "GOC:add", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0070950" ]
[ "regulates GO:0070945" ]
[ "regulates" ]
[ "GO:0070945" ]
[ "GO:0070945", "GO:0070950" ]
[ "GO:0065007", "regulates GO:0070945" ]
[]
[]
[]
[]
[]
mah
2009-10-01T02:14:36Z
false
true
2
GO:0070952
70,952
regulation of neutrophil mediated killing of gram-positive bacterium
biological_process
Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.
[ "GOC:add", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0070950" ]
[ "regulates GO:0070946" ]
[ "regulates" ]
[ "GO:0070946" ]
[ "GO:0070946", "GO:0070950" ]
[ "GO:0065007", "regulates GO:0070946" ]
[]
[]
[]
[]
[]
mah
2009-10-01T02:14:36Z
false
true
9