LiteFold/GO · Datasets at Hugging Face

GO:0070717

70,717

poly-purine tract binding

molecular_function

Binding to a stretch of purines (adenine or guanine) in an RNA molecule.

[ "GOC:mah" ]

null

[]

[ "GO:0003727" ]

[]

[ "GO:0003727" ]

[]

mah

2009-06-10T03:32:15Z

false

true

8

GO:0070718

70,718

alphaPDGFR-SHP-2 complex

cellular_component

A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.

[ "GOC:mah", "PMID:8943348" ]

null

[ "PDGFRA-SHP-2 complex, PDGF stimulated" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

mah

2009-06-10T05:00:43Z

false

true

7

GO:0070719

70,719

alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex

cellular_component

A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.

[ "GOC:mah", "PMID:8943348" ]

null

[ "PDGFRA-PLC-gamma-1-PI3K-SHP-2 complex, PDGF stimulated" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

mah

2009-06-10T05:04:20Z

false

true

9

GO:0070720

70,720

Grb2-SHP-2 complex

cellular_component

A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.

[ "GOC:mah", "PMID:8943348" ]

null

[ "GRB2-SHP-2 complex, PDGF stimulated" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

mah

2009-06-10T05:08:21Z

false

true

4

GO:0070721

70,721

ISGF3 complex

cellular_component

A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein.

[ "GOC:mah", "PMID:8943351" ]

null

[ "interferon-stimulated gene factor 3 transcription complex" ]

[ "EXACT" ]

[]

[ "GO:0090575" ]

[]

[ "GO:0090575" ]

[]

mah

2009-06-10T05:22:05Z

false

true

6

GO:0070722

70,722

Tle3-Aes complex

cellular_component

A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product.

[ "GOC:mah", "PMID:8955148" ]

null

[ "Grg3b-Grg5 complex" ]

[ "EXACT" ]

[]

[ "GO:0090571" ]

[]

[ "GO:0090571" ]

[]

mah

2009-06-10T05:45:28Z

false

true

8

GO:0070723

70,723

response to cholesterol

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.

[ "GOC:BHF", "GOC:vk" ]

null

[]

[ "GO:0036314", "GO:0097305" ]

[]

[ "GO:0036314", "GO:0097305" ]

[]

mah

2009-06-15T02:28:27Z

false

true

8

GO:0070724

70,724

BMP receptor complex

cellular_component

A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.

[ "GOC:mah", "GOC:mh", "PMID:19377468" ]

null

[ "bone morphogenetic protein receptor complex" ]

[ "EXACT" ]

[]

[ "GO:0098802" ]

[]

[ "GO:0098802" ]

[]

mah

2009-06-15T02:34:27Z

false

true

6

GO:0070725

70,725

Yb body

cellular_component

A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell.

[ "GOC:sart", "PMID:19433453", "PMID:28595904", "PMID:31267711" ]

null

[]

[ "GO:0036464" ]

[]

[ "GO:0036464" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27969\" xsd:anyURI" ]

mah

2009-06-15T05:17:28Z

false

true

4

GO:0070728

70,728

L-leucine binding

molecular_function

Binding to L-leucine, 2-amino-4-methylpentanoic acid.

[ "GOC:BHF", "GOC:mah" ]

null

[ "Leu binding", "leucine binding" ]

[ "BROAD", "BROAD" ]

[]

[ "GO:0016597", "GO:0031406", "GO:0043169" ]

[]

[ "GO:0016597", "GO:0031406", "GO:0043169" ]

[]

mah

2009-06-17T03:16:30Z

false

true

2

GO:0070729

70,729

cyclic nucleotide transport

biological_process

The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.

[ "GOC:mah", "ISBN:0198506732" ]

null

[]

[ "GO:0006862" ]

[]

[ "GO:0006862" ]

[]

mah

2009-06-17T03:49:56Z

false

true

7

GO:0070731

70,731

cGMP transport

biological_process

The directed movement of cyclic GMP (cGMP), into, out of or within a cell.

[ "GOC:mah", "ISBN:0198506732" ]

null

[ "cyclic GMP transport" ]

[ "EXACT" ]

[]

[ "GO:0001408", "GO:0015711", "GO:0015868", "GO:0070729" ]

[]

[ "GO:0001408", "GO:0015711", "GO:0015868", "GO:0070729" ]

[]

mah

2009-06-17T04:40:27Z

false

true

5

GO:0070732

70,732

spindle envelope

cellular_component

An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during pro...

[ "GOC:mah", "GOC:sart", "PMID:19417004", "PMID:6428889" ]

null

[]

[ "goslim_candida" ]

[]

[ "GO:0031967" ]

[]

[ "GO:0031967" ]

[]

mah

2009-06-18T12:00:59Z

false

true

6

GO:0070733

70,733

AMPylase activity

molecular_function

Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to L-serine, L-threonine, and L-tyrosine residues in target proteins.

[ "GOC:mah", "PMID:19039103", "PMID:19362538", "PMID:33947243" ]

null

[ "adenosine monophosphate-protein transferase activity", "AMPylator", "protein adenylyltransferase activity" ]

[ "EXACT", "RELATED", "RELATED" ]

[]

[ "EC:2.7.7.108", "RHEA:54288", "RHEA:54292", "RHEA:58120" ]

[ "GO:0070566" ]

[]

[ "GO:0070566" ]

[]

[ "skos:exactMatch EC:2.7.7.108", "skos:narrowMatch RHEA:54288", "skos:narrowMatch RHEA:54292", "skos:narrowMatch RHEA:58120", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25168\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25802\" xsd:anyU...

mah

2009-06-18T01:09:15Z

false

true

5

GO:0070734

70,734

obsolete histone H3-K27 methylation

biological_process

OBSOLETE. The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.

[ "GOC:mah", "GOC:pr" ]

This term was obsoleted because it represents a molecular function.

[ "histone H3 K27 methylation", "histone H3K27me", "histone lysine H3 K27 methylation" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

mah

2009-06-19T11:44:37Z

true

8

GO:0070735

70,735

protein-glycine ligase activity

molecular_function

Catalysis of the reaction: ATP + glycine + L-glutamyl-[protein] = ADP + glycyl-L-glutamyl-[protein] + H+ + phosphate.

[ "RHEA:67180" ]

null

[ "protein glycylase activity" ]

[ "EXACT" ]

[]

[ "Reactome:R-HSA-8867370 \"TTLL3, TTLL8, TTLL10 polyglycylate tubulin\"", "RHEA:67180" ]

[ "GO:0016881", "GO:0140096" ]

[]

[ "GO:0016881", "GO:0140096" ]

[]

[ "skos:exactMatch RHEA:67180", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25720\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

mah

2009-06-19T01:51:21Z

false

true

6

GO:0070736

70,736

protein-glycine ligase activity, initiating

molecular_function

Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein.

[ "GOC:mah", "PMID:19524510" ]

null

[ "protein glycylase activity, initiating" ]

[ "EXACT" ]

[]

[ "GO:0070735" ]

[]

[ "GO:0070735" ]

[]

mah

2009-06-19T01:56:32Z

false

true

8

GO:0070737

70,737

protein-glycine ligase activity, elongating

molecular_function

Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain.

[ "GOC:mah", "PMID:19524510" ]

null

[ "protein glycylase activity, elongating" ]

[ "EXACT" ]

[]

[ "GO:0070735" ]

[]

[ "GO:0070735" ]

[]

mah

2009-06-19T02:00:21Z

false

true

9

GO:0070738

70,738

tubulin-glycine ligase activity

molecular_function

Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.

[ "GOC:mah", "PMID:19524510" ]

null

[ "tubulin glycylase activity" ]

[ "EXACT" ]

[]

[ "GO:0070735" ]

[]

[ "GO:0070735" ]

[]

[ "skos:broadMatch RHEA:67180", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]

mah

2009-06-19T02:02:01Z

false

true

7

GO:0070739

70,739

protein-glutamic acid ligase activity

molecular_function

Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein.

[ "GOC:mah", "PMID:19524510" ]

null

[ "protein glutamylase activity", "protein-glutamate ligase activity" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0016881", "GO:0140096" ]

[]

[ "GO:0016881", "GO:0140096" ]

[]

mah

2009-06-19T02:23:22Z

false

true

3

GO:0070740

70,740

tubulin-glutamic acid ligase activity

molecular_function

Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule.

[ "GOC:mah", "PMID:19524510" ]

null

[ "tubulin glutamylase activity", "tubulin-glutamate ligase activity" ]

[ "EXACT", "EXACT" ]

[]

[ "EC:6.3.2.61", "Reactome:R-HSA-8865774 \"TTLLs polyglutamylate tubulin\"", "Reactome:R-HSA-8955869 \"Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin\"" ]

[ "GO:0070739" ]

[]

[ "GO:0070739" ]

[]

[ "skos:exactMatch EC:6.3.2.61", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23409\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

mah

2009-06-19T02:26:15Z

false

true

7

GO:0070741

70,741

response to interleukin-6

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.

[ "GOC:mah" ]

null

[ "response to IL-6" ]

[ "EXACT" ]

[]

[ "GO:0034097" ]

[]

[ "GO:0034097" ]

[]

mah

2009-06-19T03:39:12Z

false

true

7

GO:0070742

70,742

C2H2 zinc finger domain binding

molecular_function

Binding to a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.

[ "GOC:BHF", "GOC:mah", "Pfam:PF00096" ]

null

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

mah

2009-06-23T11:26:02Z

false

true

8

GO:0070743

70,743

interleukin-23 complex

cellular_component

A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.

[ "GOC:add", "PMID:11114383", "PMID:15999093" ]

Note that this heterodimeric cytokine utilizes the same beta subunit as IL-12.

[ "IL-23 complex", "IL12B", "IL23A", "p19", "p40" ]

[ "EXACT", "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0140392" ]

[]

[ "GO:0140392" ]

[]

mah

2009-06-23T01:06:02Z

false

true

9

GO:0070745

70,745

interleukin-35 complex

cellular_component

A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.

[ "GOC:add", "PMID:19161428", "PMID:19161429" ]

Note that this heterodimeric cytokine utilizes the same IL-12p35 subunit as its alpha chain as IL-12 uses and the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-27 uses. IL-35 requires both subunits -- there is no separate IL35 gene.

[ "EBI3", "IL-35 complex", "IL12A", "p35" ]

[ "NARROW", "EXACT", "NARROW", "NARROW" ]

[]

[ "GO:0140392" ]

[]

[ "GO:0140392" ]

[]

mah

2009-06-23T01:13:14Z

false

true

3

GO:0070746

70,746

interleukin-35 binding

molecular_function

Binding to interleukin-35.

[ "GOC:add" ]

null

[ "IL-35 binding" ]

[ "EXACT" ]

[]

[ "GO:0019955" ]

[]

[ "GO:0019955" ]

[]

mah

2009-06-23T01:15:36Z

false

true

1

GO:0070747

70,747

interleukin-35 receptor activity

molecular_function

Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

[ "GOC:add", "GOC:signaling" ]

null

[ "IL-35 receptor activity", "IL-35R" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0004896" ]

[ "has_part GO:0070746", "part_of GO:0070757" ]

[ "has_part", "part_of" ]

[ "GO:0070746", "GO:0070757" ]

[ "GO:0004896", "GO:0070746", "GO:0070757" ]

[]

mah

2009-06-23T01:18:09Z

false

true

8

GO:0070748

70,748

interleukin-35 receptor binding

molecular_function

Binding to an interleukin-35 receptor.

[ "GOC:add" ]

null

[ "IL-35", "interleukin-35 receptor ligand" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0005126" ]

[]

[ "GO:0005126" ]

[]

mah

2009-06-23T01:21:54Z

false

true

7

GO:0070753

70,753

interleukin-35 production

biological_process

The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

[ "GOC:mah" ]

null

[ "IL-35 production", "interleukin-35 biosynthetic process", "interleukin-35 secretion" ]

[ "EXACT", "NARROW", "NARROW" ]

[ "GO:0070749", "GO:0072626" ]

[ "gocheck_do_not_annotate" ]

[]

[ "GO:0001816" ]

[]

[ "GO:0001816" ]

[]

mah

2009-06-23T01:25:11Z

false

true

7

GO:0070754

70,754

regulation of interleukin-35 production

biological_process

Any process that modulates the frequency, rate, or extent of interleukin-35 production.

[ "GOC:mah" ]

null

[ "regulation of IL-35 production", "regulation of interleukin-35 biosynthetic process" ]

[ "EXACT", "NARROW" ]

[ "GO:0070750" ]

[]

[ "GO:0001817" ]

[ "regulates GO:0070753" ]

[ "regulates" ]

[ "GO:0070753" ]

[ "GO:0001817", "GO:0070753" ]

[ "GO:0065007", "regulates GO:0070753" ]

[]

mah

2009-06-23T01:29:17Z

false

true

5

GO:0070755

70,755

negative regulation of interleukin-35 production

biological_process

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.

[ "GOC:mah" ]

null

[ "down regulation of interleukin-35 production", "down-regulation of interleukin-35 production", "downregulation of interleukin-35 production", "inhibition of interleukin-35 production", "negative regulation of IL-35 production", "negative regulation of interleukin-35 biosynthetic process" ]

[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "NARROW" ]

[ "GO:0070751" ]

[]

[ "GO:0001818", "GO:0070754" ]

[ "negatively_regulates GO:0070753" ]

[ "negatively_regulates" ]

[ "GO:0070753" ]

[ "GO:0001818", "GO:0070753", "GO:0070754" ]

[ "GO:0065007", "negatively_regulates GO:0070753" ]

[]

mah

2009-06-23T01:34:54Z

false

true

9

GO:0070756

70,756

positive regulation of interleukin-35 production

biological_process

Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.

[ "GOC:mah" ]

null

[ "activation of interleukin-35 production", "positive regulation of IL-35 production", "positive regulation of interleukin-35 biosynthetic process", "stimulation of interleukin-35 production", "up regulation of interleukin-35 production", "up-regulation of interleukin-35 production", "upregulation of int...

[ "NARROW", "EXACT", "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]

[ "GO:0070752" ]

[]

[ "GO:0001819", "GO:0070754" ]

[ "positively_regulates GO:0070753" ]

[ "positively_regulates" ]

[ "GO:0070753" ]

[ "GO:0001819", "GO:0070753", "GO:0070754" ]

[ "GO:0065007", "positively_regulates GO:0070753" ]

[]

mah

2009-06-23T01:39:45Z

false

true

5

GO:0070757

70,757

interleukin-35-mediated signaling pathway

biological_process

The series of molecular signals initiated by interleukin-35 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

[ "GOC:add", "GOC:mah", "GOC:signaling" ]

null

[ "IL-35-mediated signaling pathway", "interleukin-35-mediated signalling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "Reactome:R-HSA-8984722 \"Interleukin-35 Signalling\"" ]

[ "GO:0019221" ]

[]

[ "GO:0019221" ]

[]

mah

2009-06-23T01:55:02Z

false

true

2

GO:0070758

70,758

regulation of interleukin-35-mediated signaling pathway

biological_process

Any process that modulates the rate, frequency or extent of an interleukin-35-mediated signaling pathway.

[ "GOC:mah" ]

null

[ "regulation of IL-35-mediated signaling pathway", "regulation of interleukin-35-mediated signalling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0001959" ]

[ "regulates GO:0070757" ]

[ "regulates" ]

[ "GO:0070757" ]

[ "GO:0001959", "GO:0070757" ]

[ "GO:0065007", "regulates GO:0070757" ]

[]

mah

2009-06-23T01:58:43Z

false

true

5

GO:0070759

70,759

negative regulation of interleukin-35-mediated signaling pathway

biological_process

Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.

[ "GOC:mah" ]

null

[ "negative regulation of IL-35-mediated signaling pathway", "negative regulation of interleukin-35-mediated signalling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0001960", "GO:0070758" ]

[ "negatively_regulates GO:0070757" ]

[ "negatively_regulates" ]

[ "GO:0070757" ]

[ "GO:0001960", "GO:0070757", "GO:0070758" ]

[ "GO:0065007", "negatively_regulates GO:0070757" ]

[]

mah

2009-06-23T02:02:07Z

false

true

4

GO:0070760

70,760

positive regulation of interleukin-35-mediated signaling pathway

biological_process

Any process that increases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.

[ "GOC:mah" ]

null

[ "positive regulation of IL-35-mediated signaling pathway", "positive regulation of interleukin-35-mediated signalling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0001961", "GO:0070758" ]

[ "positively_regulates GO:0070757" ]

[ "positively_regulates" ]

[ "GO:0070757" ]

[ "GO:0001961", "GO:0070757", "GO:0070758" ]

[ "GO:0065007", "positively_regulates GO:0070757" ]

[]

mah

2009-06-23T02:06:16Z

false

true

2

GO:0070761

70,761

pre-snoRNP complex

cellular_component

A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.

[ "GOC:BHF", "GOC:mah", "GOC:rl", "PMID:17636026", "PMID:17709390" ]

null

[ "pre-small nucleolar ribonucleoprotein complex" ]

[ "EXACT" ]

[]

[ "GO:1990904" ]

[]

[ "GO:1990904" ]

[]

mah

2009-06-23T02:32:10Z

false

true

6

GO:0070762

70,762

nuclear pore transmembrane ring

cellular_component

A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes...

[ "GOC:dgf", "PMID:18046406", "PMID:19524430", "PMID:20947011", "PMID:22419078" ]

null

[ "NDC1 complex", "NDC1 subcomplex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0140513" ]

[ "part_of GO:0005643" ]

[ "part_of" ]

[ "GO:0005643" ]

[ "GO:0005643", "GO:0140513" ]

[]

mah

2009-06-29T11:02:56Z

false

true

7

GO:0070763

70,763

Delta1 complex

cellular_component

A protein complex that consists of homodimer of the Notch ligand Delta1.

[ "PMID:12794186" ]

null

[ "Delta1 homodimer complex" ]

[ "EXACT" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

mah

2009-06-29T01:04:12Z

false

true

4

GO:0070764

70,764

gamma-secretase-Delta1 complex

cellular_component

A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex.

[ "PMID:12794186" ]

null

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

mah

2009-06-29T01:11:51Z

false

true

1

GO:0070765

70,765

gamma-secretase complex

cellular_component

A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different sub...

[ "GOC:krc", "PMID:15286082", "PMID:15890777", "PMID:17047368", "PMID:22122073", "PMID:25565961", "PMID:28320827", "PMID:32616437" ]

null

[ "CD147-gamma-secretase complex (APH-1a, PS-1, PEN-2, NCT variant)", "gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN variant)", "gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN)", "gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN)", "gamma-secretase complex (APH1B, PSEN2, PSENEN, NCSTN)", "p...

[ "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "EXACT", "NARROW", "NARROW" ]

[]

[ "GO:0098797", "GO:1902494" ]

[]

[ "GO:0098797", "GO:1902494" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20317\" xsd:anyURI" ]

mah

2009-06-29T01:33:19Z

false

true

3

GO:0070766

70,766

endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex

cellular_component

A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof).

[ "PMID:8973549" ]

null

[ "SNARE complex (Stx4, Napa, Vamp3, Nsf, Vamp2)", "Stx4-Napa-Vamp3-Nsf-Vamp2 complex" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0031201" ]

[]

[ "GO:0031201" ]

[]

mah

2009-06-29T04:41:55Z

false

true

1

GO:0070768

70,768

synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex

cellular_component

A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).

[ "PMID:8999968" ]

null

[ "Snap25-Syt1-Unc13b-Vamp2-Stx1b2-Stx1a complex", "SNARE complex (Snap25, Syt1, Unc13b, Vamp2, Stx1b2, Stx1a)" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0031201" ]

[]

[ "GO:0031201" ]

[]

mah

2009-06-29T05:14:04Z

false

true

5

GO:0070769

70,769

alphaIIb-beta3 integrin-CIB complex

cellular_component

A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.

[ "PMID:9030514" ]

null

[ "ITGA2B-ITGB3-CIB1 complex" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

mah

2009-06-29T05:20:01Z

false

true

2

GO:0070770

70,770

alphaIIb-beta3 integrin-CD47-FAK complex

cellular_component

A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.

[ "PMID:9169439" ]

null

[ "ITGA2b-ITGB3-CD47-FAK complex" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

mah

2009-06-29T05:43:59Z

false

true

5

GO:0070771

70,771

alphaIIb-beta3 integrin-CD47-Src complex

cellular_component

A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.

[ "PMID:9169439" ]

null

[ "ITGA2b-ITGB3-CD47-SRC complex" ]

[ "NARROW" ]

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

mah

2009-06-29T05:46:53Z

false

true

6

GO:0070772

70,772

PAS complex

cellular_component

A phosphatidylinositol kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKFYVE in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate....

[ "PMID:18950639", "PMID:19037259", "PMID:19158662" ]

null

[ "autophagy-specific phosphatidylinositol 3-kinase complex" ]

[ "RELATED" ]

[]

[ "GO:0061695", "GO:0098796" ]

[ "part_of GO:0005774" ]

[ "part_of" ]

[ "GO:0005774" ]

[ "GO:0005774", "GO:0061695", "GO:0098796" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27700\" xsd:anyURI" ]

mah

2009-06-30T11:13:32Z

false

true

5

GO:0070773

70,773

protein-N-terminal glutamine amidohydrolase activity

molecular_function

Catalysis of the reaction: N-terminal L-glutaminyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + NH4+. This reaction is the deamidation of an N-terminal glutamine residue of a protein.

[ "PMID:19560421", "RHEA:50680" ]

null

[ "NtQ-amidase activity" ]

[ "EXACT" ]

[]

[ "EC:3.5.1.122", "RHEA:50680" ]

[ "GO:0016811", "GO:0140096" ]

[]

[ "GO:0016811", "GO:0140096" ]

[]

[ "skos:exactMatch EC:3.5.1.122", "skos:exactMatch RHEA:50680", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23341\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

mah

2009-06-30T11:34:08Z

false

true

2

GO:0070774

70,774

obsolete phytoceramidase activity

molecular_function

OBSOLETE. Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine.

[ "GOC:pde", "PMID:11356846" ]

The reason for obsoletion is that this term represents a specific substrate of GO:0017040 N-acylsphingosine amidohydrolase activity.

[]

[ "GO:0017040" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28294\" xsd:anyURI" ]

mah

2009-07-02T10:52:42Z

true

1

GO:0070775

70,775

H3 histone acetyltransferase complex

cellular_component

A multisubunit complex that catalyzes the acetylation of histone H3.

[ "GOC:mah" ]

null

[ "H3 HAT complex" ]

[ "EXACT" ]

[]

[ "GO:0000123" ]

[]

[ "GO:0000123" ]

[]

mah

2009-07-02T11:56:48Z

false

true

2

GO:0070776

70,776

MOZ/MORF histone acetyltransferase complex

cellular_component

A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.

[ "PMID:18794358" ]

null

[]

[ "GO:0070775" ]

[]

[ "GO:0070775" ]

[]

mah

2009-07-02T12:06:04Z

false

true

5

GO:0070777

70,777

D-aspartate transmembrane transport

biological_process

The process in which D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid is transported across a lipid bilayer, from one side of a membrane to the other, by means of some agent such as a transporter or pore.

[ "GOC:mah", "GOC:rph" ]

null

[]

[ "GO:0015810", "GO:0042940" ]

[]

[ "GO:0015810", "GO:0042940" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26844\" xsd:anyURI" ]

mah

2009-07-02T01:42:57Z

false

true

7

GO:0070778

70,778

L-aspartate transmembrane transport

biological_process

The directed movement of L-aspartate across a membrane by means of some agent such as a transporter or a pore.

[ "PMID:21307582" ]

null

[ "L-aspartate transport" ]

[ "BROAD" ]

[ "GO:0089712" ]

[]

[ "GO:0015810", "GO:1902475" ]

[]

[ "GO:0015810", "GO:1902475" ]

[]

mah

2009-07-02T01:46:31Z

false

true

4

GO:0070779

70,779

D-aspartate import across plasma membrane

biological_process

The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.

[ "PMID:7914198" ]

null

[ "D-aspartate import", "D-aspartate import into cell", "D-aspartate uptake" ]

[ "BROAD", "EXACT", "EXACT" ]

[ "GO:0140016" ]

[]

[ "GO:0070777", "GO:0089718" ]

[]

[ "GO:0070777", "GO:0089718" ]

[]

mah

2009-07-02T01:57:00Z

false

true

9

GO:0070781

70,781

response to biotin

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.

[ "GOC:sl" ]

null

[ "response to Bios IIB", "response to coenzyme R", "response to vitamin B7", "response to vitamin H" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0033273", "GO:1901698", "GO:1901700" ]

[]

[ "GO:0033273", "GO:1901698", "GO:1901700" ]

[]

mah

2009-07-02T02:34:43Z

false

true

1

GO:0070782

70,782

phosphatidylserine exposure on apoptotic cell surface

biological_process

A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.

[ "GOC:mah", "GOC:mtg_apoptosis", "GOC:rk", "PMID:11536005" ]

In normal cells, phosphatidylserine residues are found exclusively on the inner side of the cellular membrane. During apoptosis, phosphatidylserine is transported to the outer cell surface by scramblase proteins. This event acts as an "eat-me" signal for macrophages to dispose of the dying cell. When annotating to this...

[ "externalization of phosphatidylserine" ]

[ "EXACT" ]

[]

[ "GO:0017121" ]

[ "has_part GO:0017128", "part_of GO:0097194" ]

[ "has_part", "part_of" ]

[ "GO:0017128", "GO:0097194" ]

[ "GO:0017121", "GO:0017128", "GO:0097194" ]

[]

mah

2009-07-02T02:41:44Z

false

true

8

GO:0070783

70,783

growth of unicellular organism as a thread of attached cells

biological_process

A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.

[ "GOC:mah", "GOC:mcc" ]

null

[]

[ "goslim_candida" ]

[]

[ "GO:0044182" ]

[]

[ "GO:0044182" ]

[]

mah

2009-07-07T02:21:14Z

false

true

3

GO:0070784

70,784

regulation of growth of unicellular organism as a thread of attached cells

biological_process

Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.

[ "GOC:mah" ]

null

[]

[ "GO:1900428" ]

[ "regulates GO:0070783" ]

[ "regulates" ]

[ "GO:0070783" ]

[ "GO:0070783", "GO:1900428" ]

[ "GO:0065007", "regulates GO:0070783" ]

[]

mah

2009-07-07T02:34:59Z

false

true

3

GO:0070785

70,785

negative regulation of growth of unicellular organism as a thread of attached cells

biological_process

Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.

[ "GOC:mah" ]

null

[]

[ "GO:0070784", "GO:1900429" ]

[ "negatively_regulates GO:0070783" ]

[ "negatively_regulates" ]

[ "GO:0070783" ]

[ "GO:0070783", "GO:0070784", "GO:1900429" ]

[ "GO:0065007", "negatively_regulates GO:0070783" ]

[]

mah

2009-07-07T02:37:21Z

false

true

1

GO:0070786

70,786

positive regulation of growth of unicellular organism as a thread of attached cells

biological_process

Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.

[ "GOC:mah" ]

null

[]

[ "GO:0070784", "GO:1900430" ]

[ "positively_regulates GO:0070783" ]

[ "positively_regulates" ]

[ "GO:0070783" ]

[ "GO:0070783", "GO:0070784", "GO:1900430" ]

[ "GO:0065007", "positively_regulates GO:0070783" ]

[]

mah

2009-07-07T02:39:48Z

false

true

9

GO:0070787

70,787

conidiophore development

biological_process

The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.

[ "PMID:9529886" ]

null

[]

[ "GO:0075259" ]

[]

[ "GO:0075259" ]

[]

mah

2009-07-08T01:30:36Z

false

true

6

GO:0070788

70,788

conidiophore stalk development

biological_process

The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.

[ "PMID:9529886" ]

null

[]

[ "GO:0003006", "GO:0048856" ]

[ "part_of GO:0070787" ]

[ "part_of" ]

[ "GO:0070787" ]

[ "GO:0003006", "GO:0048856", "GO:0070787" ]

[]

mah

2009-07-08T01:31:44Z

false

true

2

GO:0070789

70,789

metula development

biological_process

The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.

[ "PMID:9529886" ]

null

[ "development of primary sterigmata" ]

[ "EXACT" ]

[]

[ "GO:0003006", "GO:0048468" ]

[ "part_of GO:0070787" ]

[ "part_of" ]

[ "GO:0070787" ]

[ "GO:0003006", "GO:0048468", "GO:0070787" ]

[]

mah

2009-07-08T01:33:46Z

false

true

4

GO:0070790

70,790

phialide development

biological_process

The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips.

[ "PMID:9529886" ]

null

[ "development of secondary sterigmata" ]

[ "EXACT" ]

[]

[ "GO:0003006", "GO:0048468" ]

[ "part_of GO:0070787" ]

[ "part_of" ]

[ "GO:0070787" ]

[ "GO:0003006", "GO:0048468", "GO:0070787" ]

[]

mah

2009-07-08T02:32:30Z

false

true

3

GO:0070792

70,792

Hulle cell development

biological_process

The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fru...

[ "PMID:19210625" ]

null

[ "Huelle cell development", "Hulle cell formation" ]

[ "EXACT", "NARROW" ]

[]

[ "GO:0003006", "GO:0048468" ]

[ "part_of GO:0070791" ]

[ "part_of" ]

[ "GO:0070791" ]

[ "GO:0003006", "GO:0048468", "GO:0070791" ]

[]

mah

2009-07-08T02:54:30Z

false

true

3

GO:0070793

70,793

regulation of conidiophore development

biological_process

Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.

[ "GOC:mah" ]

null

[]

[ "GO:0075260" ]

[ "regulates GO:0070787" ]

[ "regulates" ]

[ "GO:0070787" ]

[ "GO:0070787", "GO:0075260" ]

[ "GO:0065007", "regulates GO:0070787" ]

[]

mah

2009-07-08T03:04:29Z

false

true

8

GO:0070794

70,794

negative regulation of conidiophore development

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.

[ "GOC:mah" ]

null

[]

[ "GO:0070793", "GO:0075262" ]

[ "negatively_regulates GO:0070787" ]

[ "negatively_regulates" ]

[ "GO:0070787" ]

[ "GO:0070787", "GO:0070793", "GO:0075262" ]

[ "GO:0065007", "negatively_regulates GO:0070787" ]

[]

mah

2009-07-08T03:06:48Z

false

true

6

GO:0070795

70,795

positive regulation of conidiophore development

biological_process

Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.

[ "GOC:mah" ]

null

[]

[ "GO:0070793", "GO:0075261" ]

[ "positively_regulates GO:0070787" ]

[ "positively_regulates" ]

[ "GO:0070787" ]

[ "GO:0070787", "GO:0070793", "GO:0075261" ]

[ "GO:0065007", "positively_regulates GO:0070787" ]

[]

mah

2009-07-08T03:08:29Z

false

true

2

GO:0070797

70,797

negative regulation of cleistothecium development

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as me...

[ "GOC:mah" ]

null

[]

[ "GO:0070796", "GO:1902059" ]

[ "negatively_regulates GO:0070791" ]

[ "negatively_regulates" ]

[ "GO:0070791" ]

[ "GO:0070791", "GO:0070796", "GO:1902059" ]

[ "GO:0065007", "negatively_regulates GO:0070791" ]

[]

mah

2009-07-08T03:36:12Z

false

true

4

GO:0070798

70,798

positive regulation of cleistothecium development

biological_process

Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members...

[ "GOC:mah" ]

null

[]

[ "GO:0070796", "GO:1902060" ]

[ "positively_regulates GO:0070791" ]

[ "positively_regulates" ]

[ "GO:0070791" ]

[ "GO:0070791", "GO:0070796", "GO:1902060" ]

[ "GO:0065007", "positively_regulates GO:0070791" ]

[]

mah

2009-07-08T03:36:43Z

false

true

5

GO:0070799

70,799

regulation of conidiophore stalk development

biological_process

Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, ...

[ "GOC:mah" ]

null

[]

[ "GO:0050793", "GO:2000241" ]

[ "regulates GO:0070788" ]

[ "regulates" ]

[ "GO:0070788" ]

[ "GO:0050793", "GO:0070788", "GO:2000241" ]

[ "GO:0065007", "regulates GO:0070788" ]

[]

mah

2009-07-08T04:03:40Z

false

true

8

GO:0070800

70,800

negative regulation of conidiophore stalk development

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, o...

[ "GOC:mah" ]

null

[]

[ "GO:0051093", "GO:0070799", "GO:2000242" ]

[ "negatively_regulates GO:0070788" ]

[ "negatively_regulates" ]

[ "GO:0070788" ]

[ "GO:0051093", "GO:0070788", "GO:0070799", "GO:2000242" ]

[ "GO:0065007", "negatively_regulates GO:0070788" ]

[]

mah

2009-07-08T04:10:42Z

false

true

3

GO:0070801

70,801

positive regulation of conidiophore stalk development

biological_process

Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or ase...

[ "GOC:mah" ]

null

[]

[ "GO:0070795", "GO:0070799" ]

[ "positively_regulates GO:0070788" ]

[ "positively_regulates" ]

[ "GO:0070788" ]

[ "GO:0070788", "GO:0070795", "GO:0070799" ]

[ "GO:0065007", "positively_regulates GO:0070788" ]

[]

mah

2009-07-08T04:11:22Z

false

true

4

GO:0070802

70,802

regulation of metula development

biological_process

Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.

[ "GOC:mah" ]

null

[]

[ "GO:0060284", "GO:0070793" ]

[ "regulates GO:0070789" ]

[ "regulates" ]

[ "GO:0070789" ]

[ "GO:0060284", "GO:0070789", "GO:0070793" ]

[ "GO:0065007", "regulates GO:0070789" ]

[]

mah

2009-07-08T04:14:34Z

false

true

5

GO:0070803

70,803

negative regulation of metula development

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.

[ "GOC:mah" ]

null

[]

[ "GO:0010721", "GO:0070802", "GO:2000242" ]

[ "negatively_regulates GO:0070789" ]

[ "negatively_regulates" ]

[ "GO:0070789" ]

[ "GO:0010721", "GO:0070789", "GO:0070802", "GO:2000242" ]

[ "GO:0065007", "negatively_regulates GO:0070789" ]

[]

mah

2009-07-08T04:38:04Z

false

true

1

GO:0070804

70,804

positive regulation of metula development

biological_process

Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.

[ "GOC:mah" ]

null

[]

[ "GO:0010720", "GO:0070802", "GO:2000243" ]

[ "positively_regulates GO:0070789" ]

[ "positively_regulates" ]

[ "GO:0070789" ]

[ "GO:0010720", "GO:0070789", "GO:0070802", "GO:2000243" ]

[ "GO:0065007", "positively_regulates GO:0070789" ]

[]

mah

2009-07-08T04:38:33Z

false

true

2

GO:0070805

70,805

regulation of phialide development

biological_process

Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.

[ "GOC:mah" ]

null

[]

[ "GO:0060284", "GO:2000241" ]

[ "regulates GO:0070790" ]

[ "regulates" ]

[ "GO:0070790" ]

[ "GO:0060284", "GO:0070790", "GO:2000241" ]

[ "GO:0065007", "regulates GO:0070790" ]

[]

mah

2009-07-08T04:45:03Z

false

true

9

GO:0070806

70,806

negative regulation of phialide development

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.

[ "GOC:mah" ]

null

[]

[ "GO:0010721", "GO:0070794", "GO:0070805" ]

[ "negatively_regulates GO:0070790" ]

[ "negatively_regulates" ]

[ "GO:0070790" ]

[ "GO:0010721", "GO:0070790", "GO:0070794", "GO:0070805" ]

[ "GO:0065007", "negatively_regulates GO:0070790" ]

[]

mah

2009-07-08T04:47:16Z

false

true

4

GO:0070807

70,807

positive regulation of phialide development

biological_process

Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.

[ "GOC:mah" ]

null

[]

[ "GO:0010720", "GO:0070805", "GO:2000243" ]

[ "positively_regulates GO:0070790" ]

[ "positively_regulates" ]

[ "GO:0070790" ]

[ "GO:0010720", "GO:0070790", "GO:0070805", "GO:2000243" ]

[ "GO:0065007", "positively_regulates GO:0070790" ]

[]

mah

2009-07-08T04:48:08Z

false

true

1

GO:0070808

70,808

regulation of Hulle cell development

biological_process

Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothec...

[ "GOC:mah" ]

null

[]

[ "GO:0060284", "GO:2000241" ]

[ "regulates GO:0070792" ]

[ "regulates" ]

[ "GO:0070792" ]

[ "GO:0060284", "GO:0070792", "GO:2000241" ]

[ "GO:0065007", "regulates GO:0070792" ]

[]

mah

2009-07-08T04:51:33Z

false

true

9

GO:0070809

70,809

negative regulation of Hulle cell development

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the deve...

[ "GOC:mah" ]

null

[]

[ "GO:0010721", "GO:0070808", "GO:2000242" ]

[ "negatively_regulates GO:0070792" ]

[ "negatively_regulates" ]

[ "GO:0070792" ]

[ "GO:0010721", "GO:0070792", "GO:0070808", "GO:2000242" ]

[ "GO:0065007", "negatively_regulates GO:0070792" ]

[]

mah

2009-07-08T04:53:11Z

false

true

6

GO:0070810

70,810

positive regulation of Hulle cell development

biological_process

Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developin...

[ "GOC:mah" ]

null

[]

[ "GO:0010720", "GO:0070808", "GO:2000243" ]

[ "positively_regulates GO:0070792" ]

[ "positively_regulates" ]

[ "GO:0070792" ]

[ "GO:0010720", "GO:0070792", "GO:0070808", "GO:2000243" ]

[ "GO:0065007", "positively_regulates GO:0070792" ]

[]

mah

2009-07-08T04:54:12Z

false

true

4

GO:0070811

70,811

glycerol-2-phosphate transmembrane transport

biological_process

The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol.

[ "GOC:mah" ]

null

[ "glycerol-2-phosphate transport" ]

[ "RELATED" ]

[]

[ "GO:0015711", "GO:0015748", "GO:0055085", "GO:1901264" ]

[]

[ "GO:0015711", "GO:0015748", "GO:0055085", "GO:1901264" ]

[]

mah

2009-07-08T04:57:38Z

false

true

5

GO:0070813

70,813

hydrogen sulfide metabolic process

biological_process

The chemical reactions and pathways involving hydrogen sulfide, H2S.

[ "GOC:mah" ]

null

[ "hydrogen sulfide metabolism", "hydrogen sulphide metabolic process", "hydrogen sulphide metabolism" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006790" ]

[]

[ "GO:0006790" ]

[]

mah

2009-07-09T10:37:32Z

false

true

1

GO:0070814

70,814

hydrogen sulfide biosynthetic process

biological_process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

[ "GOC:mah" ]

null

[ "hydrogen sulfide anabolism", "hydrogen sulfide biosynthesis", "hydrogen sulfide formation", "hydrogen sulfide synthesis", "hydrogen sulphide biosynthesis", "hydrogen sulphide biosynthetic process" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0044272", "GO:0070813" ]

[]

[ "GO:0044272", "GO:0070813" ]

[]

mah

2009-07-09T10:45:02Z

false

true

7

GO:0070815

70,815

peptidyl-lysine 5-dioxygenase activity

molecular_function

Catalysis of the reaction: L-lysyl-[protein] + 2-oxoglutarate + O2 = (5S)-5-hydroxy-L-lysyl-[protein] + succinate + CO2.

[ "PMID:19574390", "RHEA:58360" ]

null

[ "lysine hydroxylase activity", "lysine,2-oxoglutarate 5-dioxygenase activity", "lysine-2-oxoglutarate dioxygenase activity", "lysyl hydroxylase activity", "peptide-lysine 5-dioxygenase activity", "peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity", "peptidyllysine, 2-oxoglutarate:oxygen 5-...

[ "BROAD", "BROAD", "BROAD", "BROAD", "EXACT", "RELATED", "RELATED", "EXACT" ]

[]

[ "Reactome:R-HSA-9630022 \"JMJD6 dimer hydroxylates lysine residues of U2AF2\"", "RHEA:58360" ]

[ "GO:0016706", "GO:0140096" ]

[]

[ "GO:0016706", "GO:0140096" ]

[]

[ "skos:exactMatch RHEA:58360", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29801\" xsd:anyURI" ]

mah

2009-07-09T11:42:07Z

false

true

1

GO:0070816

70,816

obsolete phosphorylation of RNA polymerase II C-terminal domain

biological_process

OBSOLETE. The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively p...

[ "GOC:krc", "GOC:mah", "PMID:17079683" ]

This term was obsoleted because it represents a molecular function.

[ "CTD domain phosphorylation of RNA polymerase II", "generation of hyperphosphorylated CTD of RNA polymerase II", "generation of II(0) form of RNA polymerase II", "hyperphosphorylation of RNA polymerase II C-terminal domain" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[ "GO:0016245" ]

[]

[ "GO:0008353" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19105\" xsd:anyURI" ]

mah

2009-07-13T04:01:19Z

true

2

GO:0070817

70,817

P-TEFb-cap methyltransferase complex localization

biological_process

Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.

[ "GOC:mah" ]

null

[ "establishment and maintenance of P-TEFb-cap methyltransferase complex localization", "P-TEFb-cap methyltransferase complex localisation" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0031503" ]

[]

[ "GO:0031503" ]

[]

mah

2009-07-13T04:20:17Z

false

true

6

GO:0070818

70,818

protoporphyrinogen oxidase activity

molecular_function

Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.

[ "GOC:mah", "PMID:19583219" ]

null

[ "protoporphyrinogen IX oxidase activity", "protoporphyrinogen-IX oxidase activity", "protoporphyrinogenase activity" ]

[ "RELATED", "RELATED", "RELATED" ]

[]

[ "GO:0016627" ]

[]

[ "GO:0016627" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28776\" xsd:anyURI" ]

mah

2009-07-20T02:41:12Z

false

true

6

GO:0070819

70,819

menaquinone-dependent protoporphyrinogen oxidase activity

molecular_function

Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone.

[ "GOC:mah", "PMID:19583219" ]

null

[ "protoporphyrinogen-IX:menaquinone oxidoreductase activity" ]

[ "EXACT" ]

[]

[ "GO:0016635", "GO:0070818" ]

[]

[ "GO:0016635", "GO:0070818" ]

[]

[ "skos:broadMatch EC:1.3.3.4", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24056\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]

mah

2009-07-20T02:46:06Z

false

true

7

GO:0070820

70,820

tertiary granule

cellular_component

A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.

[ "GOC:BHF", "GOC:mah", "GOC:rl", "PMID:12070036" ]

null

[ "gelatinase granule" ]

[ "EXACT" ]

[]

[ "GO:0030141" ]

[]

[ "GO:0030141" ]

[]

mah

2009-07-20T03:57:00Z

false

true

1

GO:0070822

70,822

Sin3-type complex

cellular_component

Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1...

[ "PMID:15565322", "PMID:18292778" ]

null

[]

[ "GO:0000118" ]

[ "part_of GO:0000228", "part_of GO:0000785" ]

[ "part_of", "part_of" ]

[ "GO:0000228", "GO:0000785" ]

[ "GO:0000118", "GO:0000228", "GO:0000785" ]

[]

mah

2009-07-20T04:32:33Z

false

true

9

GO:0070823

70,823

HDA1 complex

cellular_component

A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.

[ "GOC:dgf", "GOC:mah", "PMID:11287668", "PMID:8663039" ]

null

[]

[ "GO:0000118" ]

[ "part_of GO:0000785" ]

[ "part_of" ]

[ "GO:0000785" ]

[ "GO:0000118", "GO:0000785" ]

[]

mah

2009-07-20T04:47:11Z

false

true

5

GO:0070824

70,824

SHREC complex

cellular_component

A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.

[ "GOC:mah", "PMID:17289569" ]

null

[ "Snf2/HDAC containing repressor complex", "Snf2/Hdac repressive complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0016581" ]

[]

[ "GO:0016581" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20938\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23685\" xsd:anyURI" ]

mah

2009-07-20T05:02:12Z

false

true

7

GO:0070825

70,825

chrorion micropyle

cellular_component

A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization.

[ "GOC:cvs", "GOC:mah", "PMID:18649270" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0042600" ]

[ "part_of" ]

[ "GO:0042600" ]

[ "GO:0042600", "GO:0110165" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22603\" xsd:anyURI" ]

mah

2009-07-21T05:33:09Z

false

true

3

GO:0070826

70,826

paraferritin complex

cellular_component

A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.

[ "GOC:mah", "GOC:rph", "PMID:11842004", "PMID:8639593" ]

null

[]

[ "GO:0032991" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0032991" ]

[]

mah

2009-07-23T03:05:08Z

false

true

7

GO:0070828

70,828

heterochromatin organization

biological_process

Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.

[ "GOC:mah" ]

null

[ "heterochromatin organisation" ]

[ "EXACT" ]

[]

[ "GO:0006325" ]

[]

[ "GO:0006325" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26702\" xsd:anyURI" ]

mah

2009-07-23T04:12:48Z

false

true

2

GO:0070829

70,829

obsolete heterochromatin maintenance

biological_process

OBSOLETE. The chromatin organization process that preserves heterochromatin in a stable functional or structural state.

[ "GOC:mah" ]

This term was obsoleted because it is redundant with heterochromatin organization and assembly terms.

[ "heterochromatin maintenance involved in chromatin silencing", "maintenance of chromatin silencing", "maintenance of heterochromatic silencing" ]

[ "RELATED", "RELATED", "RELATED" ]

[ "GO:0006344", "GO:0070870" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22013\" xsd:anyURI" ]

mah

2009-07-23T04:14:49Z

true

5

GO:0070830

70,830

bicellular tight junction assembly

biological_process

The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.

[ "GOC:mah" ]

null

[ "tight junction formation" ]

[ "EXACT" ]

[]

[ "Reactome:R-HSA-420029 \"Tight junction interactions\"" ]

[ "GO:0120192" ]

[ "part_of GO:0043297" ]

[ "part_of" ]

[ "GO:0043297" ]

[ "GO:0043297", "GO:0120192" ]

[]

mah

2009-07-23T04:32:38Z

false

true

3

GO:0070831

70,831

basement membrane assembly

biological_process

The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.

[ "GOC:mah" ]

Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer.

[]

[ "GO:0071711", "GO:0085029" ]

[]

[ "GO:0071711", "GO:0085029" ]

[]

mah

2009-07-23T05:01:51Z

false

true

8