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GO

Dataset card Data Studio Files
xet
 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0070602
70,602
regulation of centromeric sister chromatid cohesion
biological_process
Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.
[ "GOC:mah" ]
null
[ "regulation of sister chromatid cohesion at centromere" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007063" ]
[ "regulates GO:0070601" ]
[ "regulates" ]
[ "GO:0070601" ]
[ "GO:0007063", "GO:0070601" ]
[ "GO:0065007", "regulates GO:0070601" ]
[]
[]
[]
[]
[]
mah
2009-04-28T04:32:53Z
false
true
6
GO:0070603
70,603
SWI/SNF superfamily-type complex
cellular_component
A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.
[ "GOC:bhm", "GOC:krc", "GOC:mah", "PMID:16155938" ]
null
[ "BAF-type complex", "SWI-SNF global transcription activator complex", "SWI-SNF-type complex", "SWI/SNF-type complex", "SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex" ]
[ "EXACT", "RELATED", "EXACT", "RELATED", "RELATED" ]
[ "GO:0090544" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0140513", "GO:1904949" ]
[ "part_of GO:0000785" ]
[ "part_of" ]
[ "GO:0000785" ]
[ "GO:0000785", "GO:0140513", "GO:1904949" ]
[]
[]
[]
[]
[]
[]
mah
2009-04-29T12:55:46Z
false
true
9
GO:0070606
70,606
regulation of (1->3)-alpha-glucan biosynthetic process
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
[ "GOC:mah" ]
null
[ "regulation of 1,3-alpha-glucan anabolism", "regulation of 1,3-alpha-glucan biosynthesis", "regulation of 1,3-alpha-glucan biosynthetic process", "regulation of 1,3-alpha-glucan formation", "regulation of 1,3-alpha-glucan synthesis", "regulation of alpha-1,3 glucan anabolism", "regulation of alpha-1,3 g...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032949" ]
[ "regulates GO:0070596" ]
[ "regulates" ]
[ "GO:0070596" ]
[ "GO:0032949", "GO:0070596" ]
[ "GO:0065007", "regulates GO:0070596" ]
[]
[]
[]
[]
[]
mah
2009-04-29T01:22:45Z
false
true
3
GO:0070608
70,608
regulation of cell wall (1->3)-alpha-glucan biosynthetic process
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
[ "GOC:mah" ]
null
[ "regulation of cell wall 1,3-alpha-glucan anabolism", "regulation of cell wall 1,3-alpha-glucan biosynthesis", "regulation of cell wall 1,3-alpha-glucan biosynthetic process", "regulation of cell wall 1,3-alpha-glucan formation", "regulation of cell wall 1,3-alpha-glucan synthesis", "regulation of cell wa...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0010981", "GO:0070606" ]
[ "regulates GO:0070598" ]
[ "regulates" ]
[ "GO:0070598" ]
[ "GO:0010981", "GO:0070598", "GO:0070606" ]
[ "GO:0065007", "regulates GO:0070598" ]
[]
[]
[]
[]
[]
mah
2009-04-29T01:27:15Z
false
true
6
GO:0070609
70,609
obsolete regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
[ "GOC:mah" ]
This term was obsoleted because it is an unnecessary grouping class.
[ "regulation of ascospore wall 1,3-alpha-glucan metabolism", "regulation of ascospore wall alpha-1,3 glucan metabolic process", "regulation of ascospore wall alpha-1,3 glucan metabolism", "regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30570\" xsd:anyURI" ]
mah
2009-04-29T01:29:02Z
true
true
4
GO:0070610
70,610
regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
[ "GOC:mah" ]
null
[ "regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process", "regulation of fungal-type cell wall 1,3-alpha-glucan anabolism", "regulation of fungal-type cell wall 1,3-alpha-glucan biosynthesis", "regulation of fungal-type cell wall 1,3-alpha-glucan formation", "regulation of fungal-type cel...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032995", "GO:0070608" ]
[ "regulates GO:0070600" ]
[ "regulates" ]
[ "GO:0070600" ]
[ "GO:0032995", "GO:0070600", "GO:0070608" ]
[ "GO:0065007", "regulates GO:0070600" ]
[]
[]
[]
[]
[]
mah
2009-04-29T01:32:19Z
false
true
8
GO:0070612
70,612
histone H2AR3 methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H2A.
[ "GOC:mah", "PMID:17898714", "PMID:23451136" ]
Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue seems to be only present in animals. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across di...
[ "histone H2AR3 arginine methyltransferase activity", "histone methylase activity (H2A-R3 specific)", "histone methyltransferase activity (H2A-R3 specific)", "histone-arginine N-methyltransferase activity (H2A-R3 specific)", "histone-H2AR3 methyltransferase activity" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016274", "GO:0140940" ]
[]
[]
[]
[ "GO:0016274", "GO:0140940" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:48108", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]
mah
2009-04-29T02:06:45Z
false
true
6
GO:0070613
70,613
regulation of protein processing
biological_process
Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.
[ "GOC:mah" ]
null
[ "regulation of protein maturation by peptide bond cleavage" ]
[ "EXACT" ]
[ "GO:0010953" ]
[]
[]
[ "GO:0030162", "GO:1903317" ]
[ "regulates GO:0016485" ]
[ "regulates" ]
[ "GO:0016485" ]
[ "GO:0016485", "GO:0030162", "GO:1903317" ]
[ "GO:0065007", "regulates GO:0016485" ]
[]
[]
[]
[]
[]
mah
2009-04-29T02:49:14Z
false
true
6
GO:0070614
70,614
tungstate ion transport
biological_process
The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.
[ "GOC:dh" ]
null
[]
[]
[]
[]
[]
[ "GO:0015698" ]
[]
[]
[]
[ "GO:0015698" ]
[]
[]
[]
[]
[]
[]
mah
2009-04-29T03:07:40Z
false
true
8
GO:0070616
70,616
regulation of thiamine diphosphate biosynthetic process
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
[ "GOC:mah" ]
null
[ "regulation of thiamin diphosphate biosynthetic process", "regulation of thiamine diphosphate anabolism", "regulation of thiamine diphosphate biosynthesis", "regulation of thiamine diphosphate formation", "regulation of thiamine diphosphate synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009889", "GO:0030656", "GO:0042762", "GO:0051174" ]
[ "regulates GO:0009229" ]
[ "regulates" ]
[ "GO:0009229" ]
[ "GO:0009229", "GO:0009889", "GO:0030656", "GO:0042762", "GO:0051174" ]
[ "GO:0065007", "regulates GO:0009229" ]
[]
[]
[]
[]
[]
mah
2009-04-29T03:37:35Z
false
true
3
GO:0070617
70,617
negative regulation of thiamine diphosphate biosynthetic process
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
[ "GOC:mah" ]
null
[ "down regulation of thiamine diphosphate biosynthetic process", "down-regulation of thiamine diphosphate biosynthetic process", "downregulation of thiamine diphosphate biosynthetic process", "inhibition of thiamine diphosphate biosynthetic process", "negative regulation of thiamin diphosphate biosynthetic p...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009890", "GO:0045936", "GO:0046137", "GO:0070616" ]
[ "negatively_regulates GO:0009229" ]
[ "negatively_regulates" ]
[ "GO:0009229" ]
[ "GO:0009229", "GO:0009890", "GO:0045936", "GO:0046137", "GO:0070616" ]
[ "GO:0065007", "negatively_regulates GO:0009229" ]
[]
[]
[]
[]
[]
mah
2009-04-29T03:39:48Z
false
true
3
GO:0070618
70,618
Grb2-Sos complex
cellular_component
A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
[ "GOC:mah", "PMID:7798267", "PMID:8940013" ]
null
[ "Grb2-mSos1 complex" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[]
[]
[]
mah
2009-04-29T04:19:02Z
false
true
8
GO:0070619
70,619
Shc-Grb2-Sos complex
cellular_component
A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
[ "GOC:mah", "PMID:7970708", "PMID:8940013" ]
null
[ "Shc-Grb2-mSos1 complex, EGF stimulated" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[]
[]
[]
mah
2009-04-29T04:30:00Z
false
true
8
GO:0070620
70,620
EGFR-Grb2-Sos complex
cellular_component
A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
[ "GOC:mah", "PMID:7798267", "PMID:8940013" ]
null
[ "Egfr-Grb2-mSos1 complex, EGF stimulated" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[]
[]
[]
mah
2009-04-29T04:36:30Z
false
true
5
GO:0070621
70,621
EGFR-Shc-Grb2-Sos complex
cellular_component
A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
[ "GOC:mah", "PMID:7798267", "PMID:8940013" ]
null
[]
[]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[ "GO:0098797" ]
[]
[]
[]
[]
[]
[]
mah
2009-04-29T04:38:10Z
false
true
1
GO:0070622
70,622
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex
cellular_component
A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.
[ "GOC:mah", "PMID:8940155" ]
null
[ "N-acetylglucosamine-1-phosphotransferase complex", "UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase complex" ]
[ "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0061695" ]
[ "part_of GO:0005764" ]
[ "part_of" ]
[ "GO:0005764" ]
[ "GO:0005764", "GO:0061695" ]
[]
[]
[]
[]
[]
[]
mah
2009-04-29T04:50:35Z
false
true
9
GO:0070623
70,623
regulation of thiamine biosynthetic process
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
[ "GOC:mah" ]
null
[ "regulation of thiamin biosynthetic process", "regulation of thiamine anabolism", "regulation of thiamine biosynthesis", "regulation of thiamine formation", "regulation of thiamine synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030656", "GO:0042762", "GO:1902930" ]
[ "regulates GO:0009228" ]
[ "regulates" ]
[ "GO:0009228" ]
[ "GO:0009228", "GO:0030656", "GO:0042762", "GO:1902930" ]
[ "GO:0065007", "regulates GO:0009228" ]
[]
[]
[]
[]
[]
mah
2009-05-01T03:15:49Z
false
true
5
GO:0070624
70,624
negative regulation of thiamine biosynthetic process
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
[ "GOC:mah" ]
null
[ "down regulation of thiamine biosynthetic process", "down-regulation of thiamine biosynthetic process", "downregulation of thiamine biosynthetic process", "inhibition of thiamine biosynthetic process", "negative regulation of thiamin biosynthetic process", "negative regulation of thiamine anabolism", "n...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046137", "GO:0070623", "GO:1902931" ]
[ "negatively_regulates GO:0009228" ]
[ "negatively_regulates" ]
[ "GO:0009228" ]
[ "GO:0009228", "GO:0046137", "GO:0070623", "GO:1902931" ]
[ "GO:0065007", "negatively_regulates GO:0009228" ]
[]
[]
[]
[]
[]
mah
2009-05-01T03:20:41Z
false
true
8
GO:0070625
70,625
zymogen granule exocytosis
biological_process
The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.
[ "GOC:BHF", "GOC:vk", "PMID:17442889" ]
null
[]
[]
[]
[]
[]
[ "GO:0017156" ]
[]
[]
[]
[ "GO:0017156" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-01T03:56:02Z
false
true
7
GO:0070626
70,626
(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity
molecular_function
Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
[ "RHEA:23920" ]
null
[ "(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity", "adenylosuccinase activity", "adenylosuccinate lyase activity", "SAICAR-lyase (fumarate forming) activity", "succino AMP-lyase activity" ]
[ "RELATED", "BROAD", "BROAD", "RELATED", "BROAD" ]
[]
[]
[ "KEGG_REACTION:R04559", "MetaCyc:AICARSYN-RXN", "Reactome:R-HSA-73800 \"SAICAR => AICAR + Fumarate\"", "Reactome:R-HSA-73828 \"adenylosuccinate => adenosine 5'-monophosphate + fumarate\"", "RHEA:23920" ]
[ "GO:0016842" ]
[]
[]
[]
[ "GO:0016842" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:4.3.2.2", "skos:exactMatch RHEA:23920" ]
mah
2009-05-01T04:13:49Z
false
true
2
GO:0070628
70,628
proteasome binding
molecular_function
Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
[ "GOC:mah" ]
null
[]
[]
[]
[ "goslim_chembl" ]
[]
[ "GO:0044877" ]
[]
[]
[]
[ "GO:0044877" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-01T04:38:58Z
false
true
1
GO:0070629
70,629
(1->4)-alpha-glucan metabolic process
biological_process
The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
[ "GOC:mah" ]
null
[ "(1->4)-alpha-D-glucan metabolism", "1,4-alpha-D-glucan metabolism", "1,4-alpha-glucan metabolism", "alpha-1,4 glucan metabolic process", "alpha-1,4 glucan metabolism" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030978" ]
[]
[]
[]
[ "GO:0030978" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-01T04:45:42Z
false
true
2
GO:0070630
70,630
(1->4)-alpha-glucan biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
[ "GOC:mah" ]
null
[ "(1->4)-alpha-D-glucan anabolism", "(1->4)-alpha-D-glucan biosynthesis", "(1->4)-alpha-D-glucan formation", "(1->4)-alpha-D-glucan synthesis", "1,4-alpha-glucan anabolism", "1,4-alpha-glucan biosynthesis", "1,4-alpha-glucan biosynthetic process", "1,4-alpha-glucan formation", "1,4-alpha-glucan synth...
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030979", "GO:0070629" ]
[]
[]
[]
[ "GO:0030979", "GO:0070629" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-01T04:46:34Z
false
true
2
GO:0070631
70,631
spindle pole body localization
biological_process
Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.
[ "GOC:mah" ]
null
[ "maintenance of spindle pole body localization", "spindle pole body localisation" ]
[ "NARROW", "EXACT" ]
[ "GO:0071790", "GO:1990944" ]
[]
[]
[ "GO:0051641", "GO:0061842" ]
[]
[]
[]
[ "GO:0051641", "GO:0061842" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19149\" xsd:anyURI" ]
mah
2009-05-06T02:21:38Z
false
true
2
GO:0070633
70,633
transepithelial transport
biological_process
The directed movement of a substance from one side of an epithelium to the other.
[ "GOC:mah", "GOC:yaf", "ISBN:0716731363" ]
null
[]
[]
[]
[]
[]
[ "GO:0006810" ]
[]
[]
[]
[ "GO:0006810" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-06T03:31:02Z
false
true
3
GO:0070635
70,635
nicotinamide riboside hydrolase activity
molecular_function
Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.
[ "MetaCyc:RXN-8441", "PMID:19001417" ]
null
[ "N-ribosylnicotinamide hydrolase activity", "nicotinamide ribonucleoside hydrolase activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "MetaCyc:RXN-8441" ]
[ "GO:0016799" ]
[]
[]
[]
[ "GO:0016799" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-07T02:01:42Z
false
true
3
GO:0070636
70,636
nicotinic acid riboside hydrolase activity
molecular_function
Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.
[ "GOC:mah", "PMID:19001417" ]
null
[ "D-ribosylnicotinate hydrolase activity", "D-ribosylnicotinic acid hydrolase activity", "nicotinate ribonucleoside hydrolase activity", "nicotinate riboside hydrolase activity", "nicotinic acid ribonucleoside hydrolase activity" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016799" ]
[]
[]
[]
[ "GO:0016799" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-07T02:12:00Z
false
true
5
GO:0070637
70,637
pyridine nucleoside metabolic process
biological_process
The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.
[ "GOC:mah" ]
null
[ "pyridine nucleoside metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0009116", "GO:0072524" ]
[]
[]
[]
[ "GO:0009116", "GO:0072524" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-07T02:24:21Z
false
true
3
GO:0070638
70,638
pyridine nucleoside catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.
[ "GOC:mah" ]
null
[ "pyridine nucleoside breakdown", "pyridine nucleoside catabolism", "pyridine nucleoside degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009164", "GO:0070637", "GO:0072526" ]
[]
[]
[]
[ "GO:0009164", "GO:0070637", "GO:0072526" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-07T02:27:14Z
false
true
1
GO:0070639
70,639
obsolete vitamin D2 metabolic process
biological_process
OBSOLETE. The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.
[ "GOC:BHF", "GOC:mah" ]
This term was obsoleted because it is an unnecessary grouping class.
[ "calciferol metabolic process", "ergocalciferol metabolic process", "vitamin D2 metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]
mah
2009-05-08T02:11:35Z
true
true
1
GO:0070640
70,640
vitamin D3 metabolic process
biological_process
The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.
[ "GOC:BHF", "GOC:mah" ]
null
[ "calciol metabolic process", "cholecalciferol metabolic process", "vitamin D3 metabolism" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0042359", "GO:1902652" ]
[]
[]
[]
[ "GO:0042359", "GO:1902652" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-08T02:24:24Z
false
true
2
GO:0070641
70,641
obsolete vitamin D4 metabolic process
biological_process
OBSOLETE. The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.
[ "GOC:BHF", "GOC:mah" ]
This term was obsoleted because it is an unnecessary grouping class.
[ "vitamin D4 metabolism" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]
mah
2009-05-08T02:33:01Z
true
true
3
GO:0070642
70,642
obsolete vitamin D5 metabolic process
biological_process
OBSOLETE. The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol.
[ "GOC:BHF", "GOC:mah", "PubChem_Compound:9547700" ]
This term was obsoleted because it is an unnecessary grouping class.
[ "vitamin D5 metabolism" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30524\" xsd:anyURI" ]
mah
2009-05-08T02:47:41Z
true
true
1
GO:0070643
70,643
obsolete vitamin D 25-hydroxylase activity
molecular_function
OBSOLETE. Catalysis of the hydroxylation of C-25 of any form of vitamin D.
[ "GOC:BHF", "GOC:mah" ]
This term was obsoleted because it was an unnecessary grouping term.
[ "calciferol 25-hydroxylase activity", "cholecalciferol 25-hydroxylase activity", "ergocalciferol 25-hydroxylase activity", "vitamin D2 25-hydroxylase activity" ]
[ "NARROW", "NARROW", "NARROW", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0030343" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29330\" xsd:anyURI" ]
mah
2009-05-08T03:42:29Z
true
true
9
GO:0070644
70,644
vitamin D response element binding
molecular_function
Binding to a vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
[ "GOC:BHF", "GOC:vk", "PMID:17426122" ]
null
[ "VDRE binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0000978" ]
[]
[]
[]
[ "GO:0000978" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-08T04:23:44Z
false
true
3
GO:0070645
70,645
Ubisch body
cellular_component
A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development.
[ "GOC:ecd", "GOC:mah", "PMID:14612572", "PMID:16524248" ]
null
[ "orbicule" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0140047" ]
[ "part_of" ]
[ "GO:0140047" ]
[ "GO:0110165", "GO:0140047" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-11T11:35:33Z
false
true
1
GO:0070646
70,646
protein modification by small protein removal
biological_process
A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0070647" ]
[]
[]
[]
[ "GO:0070647" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-11T01:58:15Z
false
true
8
GO:0070647
70,647
protein modification by small protein conjugation or removal
biological_process
A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
[ "GOC:mah" ]
null
[]
[]
[]
[ "goslim_drosophila", "goslim_pombe", "goslim_yeast" ]
[]
[ "GO:0043687" ]
[]
[]
[]
[ "GO:0043687" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-11T02:54:03Z
false
true
7
GO:0070648
70,648
formin-nucleated actin cable
cellular_component
An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.
[ "PMID:14671023", "PMID:16959963" ]
null
[]
[]
[]
[]
[]
[ "GO:0097518" ]
[]
[]
[]
[ "GO:0097518" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-12T02:09:57Z
false
true
1
GO:0070649
70,649
formin-nucleated actin cable assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
[ "GOC:mah", "PMID:14671023", "PMID:16959963" ]
null
[ "formin-nucleated actin cable formation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030046", "GO:0110009" ]
[]
[]
[]
[ "GO:0030046", "GO:0110009" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-12T02:14:36Z
false
true
9
GO:0070650
70,650
actin filament bundle distribution
biological_process
Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0061572" ]
[]
[]
[]
[ "GO:0061572" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-12T02:20:58Z
false
true
3
GO:0070651
70,651
nonfunctional rRNA decay
biological_process
An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.
[ "GOC:mah", "GOC:rn", "PMID:17188037", "PMID:19390089" ]
null
[ "NRD" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0016075" ]
[]
[]
[]
[ "GO:0016075" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T02:22:49Z
false
true
3
GO:0070652
70,652
HAUS complex
cellular_component
A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.
[ "PMID:19427217" ]
null
[ "HAUS augmin complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0005875" ]
[]
[]
[]
[ "GO:0005875" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T03:21:01Z
false
true
6
GO:0070653
70,653
high-density lipoprotein particle receptor binding
molecular_function
Binding to a high-density lipoprotein receptor.
[ "GOC:BHF", "GOC:mah" ]
null
[ "HDL receptor binding", "high-density lipoprotein receptor binding" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0070325" ]
[]
[]
[]
[ "GO:0070325" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T03:44:33Z
false
true
7
GO:0070654
70,654
sensory epithelium regeneration
biological_process
The regrowth of a sensory epithelium following its loss or destruction.
[ "GOC:dsf", "PMID:19381250" ]
null
[]
[]
[]
[]
[]
[ "GO:1990399" ]
[]
[]
[]
[ "GO:1990399" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T04:02:27Z
false
true
5
GO:0070655
70,655
mechanosensory epithelium regeneration
biological_process
The regrowth of lost or destroyed mechanosensory epithelia.
[ "GOC:dsf", "PMID:19381250" ]
null
[]
[]
[]
[]
[]
[ "GO:0070654" ]
[]
[]
[]
[ "GO:0070654" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T04:05:18Z
false
true
1
GO:0070656
70,656
mechanoreceptor differentiation involved in mechanosensory epithelium regeneration
biological_process
Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.
[ "GOC:dsf", "PMID:19381250" ]
null
[]
[]
[]
[]
[]
[ "GO:0042490" ]
[ "part_of GO:0070655" ]
[ "part_of" ]
[ "GO:0070655" ]
[ "GO:0042490", "GO:0070655" ]
[ "GO:0042490", "part_of GO:0070655" ]
[]
[]
[]
[]
[]
mah
2009-05-28T04:08:13Z
false
true
9
GO:0070657
70,657
neuromast regeneration
biological_process
The regrowth of a neuromast following its loss or destruction.
[ "GOC:dsf", "PMID:19381250" ]
null
[]
[]
[]
[]
[]
[ "GO:0070655" ]
[]
[]
[]
[ "GO:0070655" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T04:11:44Z
false
true
6
GO:0070658
70,658
neuromast hair cell differentiation involved in neuromast regeneration
biological_process
Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury.
[ "GOC:dsf", "PMID:19381250" ]
null
[]
[]
[]
[]
[]
[ "GO:0048886", "GO:0070656" ]
[ "part_of GO:0070657" ]
[ "part_of" ]
[ "GO:0070657" ]
[ "GO:0048886", "GO:0070656", "GO:0070657" ]
[ "GO:0048886", "part_of GO:0070657" ]
[]
[]
[]
[]
[]
mah
2009-05-28T04:16:27Z
false
true
5
GO:0070659
70,659
inner ear sensory epithelium regeneration
biological_process
The regrowth of lost or destroyed inner ear sensory epithelia.
[ "GOC:dsf", "PMID:19381250" ]
null
[]
[]
[]
[]
[]
[ "GO:0070655" ]
[]
[]
[]
[ "GO:0070655" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T04:21:09Z
false
true
8
GO:0070660
70,660
inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration
biological_process
Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.
[ "GOC:dsf", "PMID:19381250" ]
null
[]
[]
[]
[]
[]
[ "GO:0060113", "GO:0070656" ]
[ "part_of GO:0070659" ]
[ "part_of" ]
[ "GO:0070659" ]
[ "GO:0060113", "GO:0070656", "GO:0070659" ]
[ "GO:0060113", "part_of GO:0070659" ]
[]
[]
[]
[]
[]
mah
2009-05-28T04:24:23Z
false
true
2
GO:0070661
70,661
leukocyte proliferation
biological_process
The expansion of a leukocyte population by cell division.
[ "GOC:add" ]
null
[]
[]
[]
[]
[]
[ "GO:0008283" ]
[]
[]
[]
[ "GO:0008283" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T05:25:28Z
false
true
5
GO:0070662
70,662
mast cell proliferation
biological_process
The expansion of a mast cell population by cell division.
[ "GOC:add" ]
null
[]
[]
[]
[]
[]
[ "GO:0070661" ]
[]
[]
[]
[ "GO:0070661" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-28T05:27:51Z
false
true
9
GO:0070663
70,663
regulation of leukocyte proliferation
biological_process
Any process that modulates the frequency, rate or extent of leukocyte proliferation.
[ "GOC:add", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0042127" ]
[ "regulates GO:0070661" ]
[ "regulates" ]
[ "GO:0070661" ]
[ "GO:0042127", "GO:0070661" ]
[ "GO:0065007", "regulates GO:0070661" ]
[]
[]
[]
[]
[]
mah
2009-05-28T05:30:39Z
false
true
1
GO:0070664
70,664
negative regulation of leukocyte proliferation
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.
[ "GOC:add", "GOC:mah" ]
null
[ "down regulation of leukocyte proliferation", "down-regulation of leukocyte proliferation", "downregulation of leukocyte proliferation", "inhibition of leukocyte proliferation" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0008285", "GO:0070663" ]
[ "negatively_regulates GO:0070661" ]
[ "negatively_regulates" ]
[ "GO:0070661" ]
[ "GO:0008285", "GO:0070661", "GO:0070663" ]
[ "GO:0065007", "negatively_regulates GO:0070661" ]
[]
[]
[]
[]
[]
mah
2009-05-28T05:34:50Z
false
true
4
GO:0070665
70,665
positive regulation of leukocyte proliferation
biological_process
Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.
[ "GOC:add", "GOC:mah" ]
null
[ "activation of leukocyte proliferation", "stimulation of leukocyte proliferation", "up regulation of leukocyte proliferation", "up-regulation of leukocyte proliferation", "upregulation of leukocyte proliferation" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008284", "GO:0070663" ]
[ "positively_regulates GO:0070661" ]
[ "positively_regulates" ]
[ "GO:0070661" ]
[ "GO:0008284", "GO:0070661", "GO:0070663" ]
[ "GO:0065007", "positively_regulates GO:0070661" ]
[]
[]
[]
[]
[]
mah
2009-05-28T05:36:46Z
false
true
6
GO:0070666
70,666
regulation of mast cell proliferation
biological_process
Any process that modulates the frequency, rate or extent of mast cell proliferation.
[ "GOC:add", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0070663" ]
[ "regulates GO:0070662" ]
[ "regulates" ]
[ "GO:0070662" ]
[ "GO:0070662", "GO:0070663" ]
[ "GO:0065007", "regulates GO:0070662" ]
[]
[]
[]
[]
[]
mah
2009-05-28T05:40:43Z
false
true
8
GO:0070667
70,667
negative regulation of mast cell proliferation
biological_process
Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.
[ "GOC:add", "GOC:mah" ]
null
[ "down regulation of mast cell proliferation", "down-regulation of mast cell proliferation", "downregulation of mast cell proliferation", "inhibition of mast cell proliferation" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0070664", "GO:0070666" ]
[ "negatively_regulates GO:0070662" ]
[ "negatively_regulates" ]
[ "GO:0070662" ]
[ "GO:0070662", "GO:0070664", "GO:0070666" ]
[ "GO:0065007", "negatively_regulates GO:0070662" ]
[]
[]
[]
[]
[]
mah
2009-05-28T05:45:11Z
false
true
1
GO:0070668
70,668
positive regulation of mast cell proliferation
biological_process
Any process that activates or increases the rate or extent of mast cell proliferation.
[ "GOC:add", "GOC:mah" ]
null
[ "activation of mast cell proliferation", "stimulation of mast cell proliferation", "up regulation of mast cell proliferation", "up-regulation of mast cell proliferation", "upregulation of mast cell proliferation" ]
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0070665", "GO:0070666" ]
[ "positively_regulates GO:0070662" ]
[ "positively_regulates" ]
[ "GO:0070662" ]
[ "GO:0070662", "GO:0070665", "GO:0070666" ]
[ "GO:0065007", "positively_regulates GO:0070662" ]
[]
[]
[]
[]
[]
mah
2009-05-28T05:48:30Z
false
true
8
GO:0070669
70,669
response to interleukin-2
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.
[ "GOC:mah" ]
null
[ "response to IL-2" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T09:59:43Z
false
true
1
GO:0070670
70,670
response to interleukin-4
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
[ "GOC:mah" ]
null
[ "response to IL-4" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T10:01:46Z
false
true
7
GO:0070671
70,671
response to interleukin-12
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.
[ "GOC:mah" ]
null
[ "response to IL-12" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T10:02:31Z
false
true
3
GO:0070672
70,672
response to interleukin-15
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.
[ "GOC:mah" ]
null
[ "response to IL-15" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T10:03:09Z
false
true
3
GO:0070673
70,673
response to interleukin-18
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.
[ "GOC:mah" ]
null
[ "response to IL-18" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[ "GO:0034097" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T10:03:52Z
false
true
3
GO:0070674
70,674
hypoxanthine dehydrogenase activity
molecular_function
Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+.
[ "GOC:mah", "GOC:pde" ]
null
[ "hypoxanthine oxidoreductase activity", "hypoxanthine-NAD oxidoreductase activity", "hypoxanthine/NAD(+) oxidoreductase activity", "hypoxanthine/NAD+ oxidoreductase activity", "hypoxanthine:NAD+ oxidoreductase activity", "NAD-hypoxanthine dehydrogenase activity" ]
[ "BROAD", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED" ]
[]
[]
[ "Reactome:R-HSA-9727347 \"XDH dehydrogenates hypoxanthine to form xanthine\"" ]
[ "GO:0016726" ]
[]
[]
[]
[ "GO:0016726" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T01:02:13Z
false
true
9
GO:0070675
70,675
hypoxanthine oxidase activity
molecular_function
Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.
[ "GOC:mah", "GOC:pde" ]
null
[ "hypoxanthine-xanthine oxidase activity", "hypoxanthine:O2 oxidoreductase activity", "hypoxanthine:oxygen oxidoreductase activity", "schardinger enzyme", "Schardinger enzyme activity", "xanthine oxidoreductase activity" ]
[ "BROAD", "RELATED", "RELATED", "RELATED", "RELATED", "BROAD" ]
[]
[]
[ "Reactome:R-HSA-74247 \"XDH oxidizes hypoxanthine to form xanthine\"" ]
[ "GO:0016727" ]
[]
[]
[]
[ "GO:0016727" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T01:12:55Z
false
true
9
GO:0070676
70,676
intralumenal vesicle formation
biological_process
The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
[ "GOC:jp", "PMID:19234443" ]
null
[ "endosome membrane budding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006900", "GO:0007032" ]
[ "occurs_in GO:0010008" ]
[ "occurs_in" ]
[ "GO:0010008" ]
[ "GO:0006900", "GO:0007032", "GO:0010008" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T02:02:30Z
false
true
6
GO:0070677
70,677
rRNA (cytosine-2'-O-ribose)-methyltransferase activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.
[ "GOC:mah", "PMID:19400805" ]
null
[ "rRNA (cytosine-2'-O-)-methyltransferase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0016434", "GO:0062105" ]
[]
[]
[]
[ "GO:0016434", "GO:0062105" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:58956", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
mah
2009-05-29T03:37:53Z
false
true
1
GO:0070678
70,678
preprotein binding
molecular_function
Binding to a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.
[ "GOC:imk", "GOC:mah", "PMID:12914940" ]
null
[ "unprocessed protein binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0005515" ]
[]
[]
[]
[ "GO:0005515" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T03:41:54Z
false
true
4
GO:0070679
70,679
inositol 1,4,5 trisphosphate binding
molecular_function
Binding to inositol 1,4,5 trisphosphate.
[ "GOC:BHF", "GOC:mah" ]
null
[ "InsP3 binding", "IP3 binding" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043168", "GO:0043178" ]
[]
[]
[]
[ "GO:0043168", "GO:0043178" ]
[]
[]
[]
[]
[]
[]
mah
2009-05-29T04:07:00Z
false
true
5
GO:0070681
70,681
glutaminyl-tRNAGln biosynthesis via transamidation
biological_process
A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glut...
[ "GOC:mah", "MetaCyc:PWY-5921" ]
null
[]
[]
[]
[]
[ "MetaCyc:PWY-5921" ]
[ "GO:0043039" ]
[]
[]
[]
[ "GO:0043039" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-02T03:15:57Z
false
true
5
GO:0070682
70,682
proteasome regulatory particle assembly
biological_process
The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.
[ "GOC:mah", "GOC:rb", "PMID:19412159" ]
null
[ "proteasome regulatory complex assembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0043248" ]
[]
[]
[]
[ "GO:0043248" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-02T03:46:29Z
false
true
9
GO:0070685
70,685
macropinocytic cup
cellular_component
A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in ...
[ "PMID:12538772", "PMID:16968738", "PMID:9044041" ]
null
[ "crown" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0120025" ]
[]
[]
[]
[ "GO:0120025" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-03T10:18:00Z
false
true
4
GO:0070686
70,686
macropinocytic cup membrane
cellular_component
The portion of the plasma membrane surrounding a macropinocytic cup.
[ "GOC:mah" ]
null
[ "crown membrane" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0031253" ]
[ "part_of GO:0070685" ]
[ "part_of" ]
[ "GO:0070685" ]
[ "GO:0031253", "GO:0070685" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-03T10:52:25Z
false
true
9
GO:0070687
70,687
macropinocytic cup cytoskeleton
cellular_component
The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup.
[ "GOC:mah" ]
null
[ "crown cytoskeleton" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0030864", "part_of GO:0070685" ]
[ "part_of", "part_of" ]
[ "GO:0030864", "GO:0070685" ]
[ "GO:0030864", "GO:0070685", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-03T10:59:50Z
false
true
1
GO:0070688
70,688
obsolete MLL5-L complex
cellular_component
OBSOLETE. A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N...
[ "GOC:mah", "PMID:19377461" ]
This term was made obsolete because there is no evidence for the existence of this complex.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
mah
2009-06-03T11:50:18Z
true
true
2
GO:0070689
70,689
obsolete L-threonine catabolic process to propionate
biological_process
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.
[ "GOC:bf", "GOC:mah" ]
This term was obsoleted because it represents a specific instance of a pathway that should be captured as a GO-CAM model.
[ "L-threonine breakdown to propionate", "L-threonine catabolism to propionate", "L-threonine degradation to propionate", "threonine catabolic process to propionate" ]
[ "EXACT", "EXACT", "EXACT", "BROAD" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006567" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI" ]
mah
2009-06-03T01:36:54Z
true
true
8
GO:0070690
70,690
obsolete L-threonine catabolic process to acetyl-CoA
biological_process
OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA.
[ "GOC:bf", "GOC:mah" ]
This term was obsoleted because it represents a specific instance of a pathway that should be captured as a GO-CAM model.
[ "L-threonine breakdown to acetyl-CoA", "L-threonine catabolism to acetyl-CoA", "L-threonine degradation to acetyl-CoA", "threonine catabolic process to acetyl-CoA" ]
[ "EXACT", "EXACT", "EXACT", "BROAD" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006567" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30202\" xsd:anyURI" ]
mah
2009-06-03T01:40:22Z
true
true
2
GO:0070691
70,691
P-TEFb complex
cellular_component
A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T.
[ "GOC:mah", "GOC:vw", "PMID:16721054", "PMID:19328067", "Wikipedia:P-TEFb" ]
null
[ "Bur1/Bur2 complex", "cyclin-dependent kinase 9 (Cdk9)-cyclin T1 complex", "cyclin-dependent kinase 9 (Cdk9)-cyclin T2 complex", "dimeric positive transcription elongation factor complex b", "Sgv1/Bur2 complex" ]
[ "NARROW", "NARROW", "NARROW", "RELATED", "NARROW" ]
[]
[]
[]
[ "GO:0008024" ]
[]
[]
[]
[ "GO:0008024" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-03T03:12:56Z
false
true
3
GO:0070692
70,692
CTDK-1 complex
cellular_component
A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).
[ "GOC:mah", "GOC:vw", "PMID:16721054", "PMID:19328067" ]
null
[ "C-terminal domain kinase I complex", "CTDK-I complex", "Ctk complex", "trimeric positive transcription elongation factor complex b" ]
[ "EXACT", "EXACT", "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0008024" ]
[]
[]
[]
[ "GO:0008024" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-03T03:18:04Z
false
true
7
GO:0070693
70,693
P-TEFb-cap methyltransferase complex
cellular_component
A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase.
[ "PMID:17332744", "PMID:19328067" ]
null
[ "Cdk9-Pcm1 complex", "P-TEFb-Pcm1 complex" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0140513" ]
[]
[]
[]
[ "GO:0140513" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-04T02:38:58Z
false
true
8
GO:0070694
70,694
5-hydroxymethyl-dUMP N-hydrolase activity
molecular_function
Catalysis of the reaction: 5-hydroxymethyl-dUMP + H2O = 2-deoxy-D-ribose 5-phosphate + 5-hydroxymethyluracil.
[ "PMID:17234634", "RHEA:77099" ]
null
[ "deoxynucleoside 5'-monophosphate N-glycosidase activity" ]
[ "BROAD" ]
[]
[]
[ "Reactome:R-HSA-8953339 \"DNPH1 hydrolyses dGMP\"", "RHEA:77099" ]
[ "GO:0016799" ]
[]
[]
[]
[ "GO:0016799" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:77099", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29145\" xsd:anyURI" ]
mah
2009-06-04T03:06:57Z
false
true
9
GO:0070695
70,695
FHF complex
cellular_component
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
[ "GOC:ab", "GOC:mah", "PMID:18799622" ]
Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.
[]
[]
[]
[]
[]
[ "GO:0032991" ]
[ "part_of GO:0005737" ]
[ "part_of" ]
[ "GO:0005737" ]
[ "GO:0005737", "GO:0032991" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-04T03:17:29Z
false
true
3
GO:0070696
70,696
transmembrane receptor protein serine/threonine kinase binding
molecular_function
Binding to a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.
[ "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0033612" ]
[]
[]
[]
[ "GO:0033612" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-04T03:57:42Z
false
true
6
GO:0070697
70,697
activin receptor binding
molecular_function
Binding to an activin receptor.
[ "GOC:BHF", "GOC:vk" ]
null
[]
[]
[]
[]
[]
[ "GO:0070696" ]
[]
[]
[]
[ "GO:0070696" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-04T04:02:13Z
false
true
4
GO:0070698
70,698
type I activin receptor binding
molecular_function
Binding to a type I activin receptor.
[ "GOC:BHF", "GOC:vk" ]
null
[]
[]
[]
[]
[]
[ "GO:0070697" ]
[]
[]
[]
[ "GO:0070697" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-04T04:15:21Z
false
true
6
GO:0070699
70,699
type II activin receptor binding
molecular_function
Binding to a type II activin receptor.
[ "GOC:BHF", "GOC:vk" ]
null
[]
[]
[]
[]
[]
[ "GO:0070697" ]
[]
[]
[]
[ "GO:0070697" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-04T04:16:26Z
false
true
4
GO:0070701
70,701
mucus layer
cellular_component
An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts...
[ "GOC:krc", "GOC:mah", "GOC:mm2", "PMID:18806221", "PMID:19432394", "Wikipedia:Mucin" ]
null
[ "extracellular proteinaceous gel", "mucous", "mucous layer", "mucus" ]
[ "BROAD", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005576" ]
[ "part_of" ]
[ "GO:0005576" ]
[ "GO:0005576", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T02:31:34Z
false
true
4
GO:0070702
70,702
inner mucus layer
cellular_component
The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria.
[ "GOC:mah", "GOC:mm2", "PMID:18806221", "PMID:19432394" ]
null
[]
[]
[]
[]
[]
[ "GO:0070701" ]
[]
[]
[]
[ "GO:0070701" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T02:38:55Z
false
true
7
GO:0070703
70,703
outer mucus layer
cellular_component
The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria.
[ "GOC:mah", "GOC:mm2", "PMID:18806221", "PMID:19432394" ]
null
[]
[]
[]
[]
[]
[ "GO:0070701" ]
[]
[]
[]
[ "GO:0070701" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T02:44:51Z
false
true
4
GO:0070704
70,704
sterol desaturase activity
molecular_function
Catalysis of the introduction of a double bond into a sterol molecule.
[ "GOC:mah", "GOC:vw" ]
null
[]
[]
[]
[]
[]
[ "GO:0016717" ]
[]
[]
[]
[ "GO:0016717" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29311\" xsd:anyURI" ]
mah
2009-06-08T03:53:44Z
false
true
4
GO:0070705
70,705
RNA nucleotide insertion
biological_process
The modification of an RNA molecule by insertion of one or more nucleotides.
[ "GOC:cb", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0009451" ]
[]
[]
[]
[ "GO:0009451" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T04:48:35Z
false
true
9
GO:0070707
70,707
RNA dinucleotide insertion
biological_process
The modification of an RNA molecule by insertion of a dinucleotide.
[ "GOC:cb", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0070705" ]
[]
[]
[]
[ "GO:0070705" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T04:50:59Z
false
true
1
GO:0070708
70,708
RNA cytidine insertion
biological_process
The modification of an RNA molecule by insertion of a cytidine nucleotide.
[ "GOC:cb", "GOC:mah" ]
null
[ "RNA C insertion" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070705" ]
[]
[]
[]
[ "GO:0070705" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T04:52:49Z
false
true
8
GO:0070709
70,709
RNA guanosine insertion
biological_process
The modification of an RNA molecule by insertion of a guanosine nucleotide.
[ "GOC:cb", "GOC:mah" ]
null
[ "RNA G insertion" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070705" ]
[]
[]
[]
[ "GO:0070705" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T04:57:26Z
false
true
3
GO:0070711
70,711
RNA adenosine-uridine insertion
biological_process
The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide.
[ "GOC:cb", "GOC:mah" ]
null
[ "RNA AU insertion" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070707" ]
[]
[]
[]
[ "GO:0070707" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T05:16:39Z
false
true
3
GO:0070713
70,713
RNA guanosine-cytidine insertion
biological_process
The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide.
[ "GOC:cb", "GOC:mah" ]
null
[ "RNA GC insertion" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070707" ]
[]
[]
[]
[ "GO:0070707" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T05:31:43Z
false
true
7
GO:0070714
70,714
RNA guanosine-uridine insertion
biological_process
The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide.
[ "GOC:cb", "GOC:mah" ]
null
[ "RNA GU insertion" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070707" ]
[]
[]
[]
[ "GO:0070707" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-08T05:33:20Z
false
true
6
GO:0070715
70,715
sodium-dependent organic cation transport
biological_process
The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
[ "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0015695" ]
[]
[]
[]
[ "GO:0015695" ]
[]
[]
[]
[]
[]
[]
mah
2009-06-09T03:26:27Z
false
true
4
GO:0070716
70,716
mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication
biological_process
A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.
[ "GOC:BHF", "GOC:mah" ]
null
[ "mismatch repair involved in maintenance of fidelity during DNA-dependent DNA replication" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0006298" ]
[ "part_of GO:0045005" ]
[ "part_of" ]
[ "GO:0045005" ]
[ "GO:0006298", "GO:0045005" ]
[ "GO:0006298", "part_of GO:0045005" ]
[]
[]
[]
[]
[]
mah
2009-06-09T04:00:29Z
false
true
7