LiteFold/GO · Datasets at Hugging Face

GO:0097627

97,627

high-affinity L-ornithine transmembrane transporter activity

molecular_function

Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

[ "GOC:krc", "PMID:8195186" ]

null

[ "high affinity L-ornithine transmembrane transporter activity" ]

[ "EXACT" ]

[]

[ "GO:0000064" ]

[]

[ "GO:0000064" ]

[]

pr

2014-08-20T14:26:33Z

false

true

4

GO:0097631

97,631

obsolete integral component of omegasome membrane

cellular_component

OBSOLETE. The component of the omegasome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

[ "GOC:mf", "PMID:18725538", "PMID:24591649" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "integral to omegasome membrane", "omegasome integral membrane protein" ]

[ "NARROW", "RELATED" ]

[]

[ "GO:1903349" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

null

true

2

GO:0097632

97,632

extrinsic component of phagophore assembly site membrane

cellular_component

The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

[ "GOC:mf" ]

null

[ "extrinsic component of pre-autophagosomal structure membrane", "extrinsic to phagophore assembly site membrane", "phagophore assembly site peripheral membrane" ]

[ "NARROW", "EXACT", "RELATED" ]

[]

[ "GO:0031312" ]

[ "part_of GO:0034045" ]

[ "part_of" ]

[ "GO:0034045" ]

[ "GO:0031312", "GO:0034045" ]

[ "GO:0019898", "part_of GO:0034045" ]

[]

null

false

true

7

GO:0097633

97,633

obsolete intrinsic component of phagophore assembly site membrane

cellular_component

OBSOLETE. The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.

[ "GOC:mf" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "intrinsic to phagophore assembly site membrane" ]

[ "NARROW" ]

[]

[ "GO:0034045" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

null

true

7

GO:0097634

97,634

obsolete integral component of phagophore assembly site membrane

cellular_component

OBSOLETE. The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

[ "GOC:mf" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "integral to phagophore assembly site membrane", "phagophore assembly site integral membrane protein" ]

[ "NARROW", "RELATED" ]

[]

[ "GO:0034045" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

null

true

2

GO:0097635

97,635

obsolete extrinsic component of autophagosome membrane

cellular_component

OBSOLETE. The component of the autophagosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

[ "GOC:autophagy", "GOC:mf" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "autophagic vacuole peripheral membrane", "extrinsic component of autophagic vacuole membrane", "extrinsic to autophagic vacuole membrane" ]

[ "RELATED", "EXACT", "EXACT" ]

[]

[ "GO:0000421" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

null

true

2

GO:0097637

97,637

obsolete integral component of autophagosome membrane

cellular_component

OBSOLETE. The component of the autophagosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

[ "GOC:autophagy", "GOC:mf" ]

This term was obsoleted because it represents protein topology, not a cellular component.

[ "autophagic vacuole integral membrane protein", "integral component of autophagic vacuole membrane", "integral to autophagic vacuole membrane" ]

[ "RELATED", "EXACT", "NARROW" ]

[]

[ "GO:0000421" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]

null

true

9

GO:0097638

97,638

L-arginine import across plasma membrane

biological_process

The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol.

[ "GOC:krc", "PMID:8195186" ]

null

[ "arginine import", "L-arginine import into cell" ]

[ "BROAD", "EXACT" ]

[ "GO:0090467", "GO:1902765" ]

[]

[ "GO:0015695", "GO:0089718", "GO:1902475" ]

[]

[ "GO:0015695", "GO:0089718", "GO:1902475" ]

[]

tb

2012-09-24T14:28:58Z

false

true

2

GO:0097639

97,639

L-lysine import across plasma membrane

biological_process

The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol.

[ "GOC:krc", "PMID:8195186" ]

null

[ "L-lysine import into cell" ]

[ "EXACT" ]

[ "GO:1903410" ]

[]

[ "GO:0089718", "GO:1903401" ]

[]

[ "GO:0089718", "GO:1903401" ]

[]

pr

2014-09-03T09:32:57Z

false

true

2

GO:0097640

97,640

L-ornithine import across plasma membrane

biological_process

The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol.

[ "GOC:krc", "PMID:8195186" ]

null

[ "L-ornithine import into cell" ]

[ "EXACT" ]

[ "GO:1903411" ]

[]

[ "GO:0089718", "GO:1903352" ]

[]

[ "GO:0089718", "GO:1903352" ]

[]

pr

2014-09-03T09:48:14Z

false

true

1

GO:0097641

97,641

alpha-ketoglutarate-dependent xanthine dioxygenase activity

molecular_function

Catalysis of the reaction: xanthine + 2-oxoglutarate + O2 = urate + succinate + CO2.

[ "PMID:15948966", "PMID:17429948", "RHEA:43120" ]

null

[ "2-oxoglutarate-dependent xanthine dioxygenase activity", "alpha-ketoglutarate- and Fe(II)-dependent xanthine dioxygenase activity", "alpha-ketoglutarate- and Fe(II)-dependent xanthine hydroxylase activity" ]

[ "EXACT", "RELATED", "RELATED" ]

[]

[ "EC:1.14.11.48", "MetaCyc:RXN-15841", "RHEA:43120" ]

[ "GO:0016706" ]

[]

[ "GO:0016706" ]

[]

[ "skos:exactMatch EC:1.14.11.48", "skos:exactMatch MetaCyc:RXN-15841", "skos:exactMatch RHEA:43120", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30910\" xsd:anyURI" ]

pr

2014-09-03T14:55:42Z

false

true

3

GO:0097642

97,642

calcitonin family receptor activity

molecular_function

Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.

[ "GOC:bhm", "InterPro:IPR003287", "PMID:10871296", "PMID:12037140", "PMID:18687416" ]

null

[]

[ "GO:0008528" ]

[]

[ "GO:0008528" ]

[]

pr

2014-09-08T15:32:19Z

false

true

9

GO:0097643

97,643

amylin receptor activity

molecular_function

Combining with amylin to initiate a change in cell activity.

[ "GOC:bhm", "PMID:10871296", "PMID:12037140", "PMID:18687416" ]

null

[]

[ "GO:0097642" ]

[]

[ "GO:0097642" ]

[]

pr

2014-09-08T15:34:16Z

false

true

3

GO:0097644

97,644

calcitonin family binding

molecular_function

Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).

[ "GOC:bhm", "InterPro:IPR021116", "PMID:10871296", "PMID:12037140", "PMID:18687416" ]

null

[]

[ "GO:0017046" ]

[]

[ "GO:0017046" ]

[]

pr

2014-09-08T20:50:52Z

false

true

9

GO:0097645

97,645

amylin binding

molecular_function

Binding to amylin.

[ "GOC:bhm", "PMID:10871296", "PMID:12037140", "PMID:18687416" ]

null

[]

[ "GO:0097644" ]

[]

[ "GO:0097644" ]

[]

pr

2014-09-08T20:53:03Z

false

true

3

GO:0097646

97,646

calcitonin family receptor signaling pathway

biological_process

A G protein-coupled receptor signaling pathway initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) binding to its receptor on the surface of a target cell, and ending with the regulation of a ...

[ "GOC:bhm", "PMID:10871296", "PMID:12037140", "PMID:18687416" ]

null

[ "calcitonin family receptor signalling pathway" ]

[ "EXACT" ]

[]

[ "GO:0007186" ]

[]

[ "GO:0007186" ]

[]

pr

2014-09-09T17:48:05Z

false

true

8

GO:0097647

97,647

amylin receptor signaling pathway

biological_process

A G protein-coupled receptor signaling pathway initiated by amylin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.

[ "GOC:bhm", "PMID:10871296", "PMID:12037140", "PMID:18687416" ]

null

[ "amilyn receptor signalling pathway" ]

[ "EXACT" ]

[]

[ "GO:0097646" ]

[]

[ "GO:0097646" ]

[]

pr

2014-09-09T17:49:52Z

false

true

8

GO:0097649

97,649

A axonemal microtubule

cellular_component

A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule.

[ "GOC:cilia", "ISBN:0716731363" ]

null

[ "A tubule" ]

[ "BROAD" ]

[]

[ "GO:0005879" ]

[ "part_of GO:0097545" ]

[ "part_of" ]

[ "GO:0097545" ]

[ "GO:0005879", "GO:0097545" ]

[]

pr

2014-09-10T20:41:28Z

false

true

6

GO:0097650

97,650

B axonemal microtubule

cellular_component

An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet.

[ "GOC:cilia", "ISBN:0716731363" ]

null

[ "B tubule" ]

[ "BROAD" ]

[]

[ "GO:0005879" ]

[ "part_of GO:0097545" ]

[ "part_of" ]

[ "GO:0097545" ]

[ "GO:0005879", "GO:0097545" ]

[]

pr

2014-09-10T20:43:18Z

false

true

1

GO:0097651

97,651

phosphatidylinositol 3-kinase complex, class I

cellular_component

A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4...

[ "GOC:ha", "PMID:24587488" ]

null

[ "class I phosphatidylinositol 3-kinase complex", "class I PI3K complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0005942" ]

[]

[ "GO:0005942" ]

[]

pr

2014-09-16T11:19:58Z

false

true

5

GO:0097652

97,652

phosphatidylinositol 3-kinase complex, class II

cellular_component

A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast.

[ "GOC:ha", "PMID:24587488" ]

null

[ "class II phosphatidylinositol 3-kinase complex", "class II PI3K complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0005942" ]

[]

[ "GO:0005942" ]

[]

pr

2014-09-16T13:14:17Z

false

true

3

GO:0097653

97,653

unencapsulated part of cell

cellular_component

The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures.

[ "GOC:curators" ]

null

[ "non-encapsulated part of cell" ]

[ "EXACT" ]

[]

[ "GO:0110165" ]

[ "has_part GO:0005622", "has_part GO:0005886" ]

[ "has_part", "has_part" ]

[ "GO:0005622", "GO:0005886" ]

[ "GO:0005622", "GO:0005886", "GO:0110165" ]

[]

pr

2014-09-23T12:57:14Z

false

true

4

GO:0097654

97,654

platelet SNARE complex

cellular_component

A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusi...

[ "GOC:bhm", "PMID:12130530", "PMID:19450911" ]

null

[]

[ "GO:0031201" ]

[]

[ "GO:0031201" ]

[]

pr

2014-09-24T13:50:49Z

false

true

6

GO:0097655

97,655

serpin family protein binding

molecular_function

Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority o...

[ "GOC:mr", "InterPro:IPR000215", "PMID:16737556" ]

null

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

pr

2014-09-24T16:19:31Z

false

true

9

GO:0097656

97,656

cell-cell self recognition

biological_process

A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development.

[ "GOC:pf", "PMID:21700835", "PMID:23910661" ]

Examples are the membrane proteins TgrB1 and TgrC1 in the social amoeba Dictyostelium discoideum.

[ "kin discrimination", "kin recognition", "self recognition" ]

[ "RELATED", "BROAD", "BROAD" ]

[]

[ "GO:0009988" ]

[]

[ "GO:0009988" ]

[]

pr

2014-09-24T20:58:35Z

false

true

6

GO:0097657

97,657

3',5'-nucleotide bisphosphate phosphatase activity

molecular_function

Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate.

[ "GOC:jh2", "PMID:24401123", "RHEA:43532" ]

null

[]

[ "EC:3.1.3.97", "RHEA:43532" ]

[ "GO:0016791" ]

[]

[ "GO:0016791" ]

[]

[ "skos:exactMatch EC:3.1.3.97", "skos:exactMatch RHEA:43532", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pr

2014-09-25T11:21:39Z

false

true

3

GO:0097658

97,658

Asi complex

cellular_component

A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1...

[ "GOC:mcc", "PMID:25236469" ]

null

[]

[ "GO:0000152", "GO:0098796" ]

[ "part_of GO:0005637" ]

[ "part_of" ]

[ "GO:0005637" ]

[ "GO:0000152", "GO:0005637", "GO:0098796" ]

[]

pr

2014-09-29T15:08:29Z

false

true

3

GO:0097659

97,659

obsolete nucleic acid-templated transcription

biological_process

OBSOLETE. The synthesis of an RNA transcript from a nucleic acid template (DNA or RNA).

[ "GOC:pr", "GOC:txnOH", "GOC:vw" ]

This term was obsoleted because it represents an unnecessary grouping class.

[]

[ "GO:0006366" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11369\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24383\" xsd:anyURI" ]

pr

2014-10-01T13:49:27Z

true

1

GO:0097660

97,660

SCF-Cdc4 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.

[ "GOC:jd", "GOC:vw", "PMID:9346238" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:23:13Z

false

true

1

GO:0097661

97,661

SCF-Ctf13 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae.

[ "GOC:jd", "GOC:vw", "PMID:14747994" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:25:56Z

false

true

4

GO:0097662

97,662

SCF-Das1 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae.

[ "GOC:jd", "GOC:vw", "PMID:14747994" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:26:27Z

false

true

1

GO:0097663

97,663

SCF-Dia2/Pof3 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe).

[ "GOC:jd", "GOC:vw", "PMID:14747994", "PMID:15147268" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:26:44Z

false

true

4

GO:0097664

97,664

SCF-Grr1/Pof2 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe).

[ "GOC:jd", "GOC:vw", "PMID:10213692", "PMID:15147268" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:27:10Z

false

true

8

GO:0097665

97,665

SCF-Mdm30 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae.

[ "GOC:jd", "GOC:vw", "PMID:14747994" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:27:30Z

false

true

9

GO:0097666

97,666

SCF-Met30/Pof1 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).

[ "GOC:jd", "GOC:vw", "PMID:15147268", "PMID:9499404" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:27:49Z

false

true

7

GO:0097667

97,667

SCF-Rcy1/Pof6 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe).

[ "GOC:jd", "GOC:vw", "PMID:14747994", "PMID:15147268" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:28:09Z

false

true

5

GO:0097668

97,668

SCF-Saf1/Pof9 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe).

[ "GOC:jd", "GOC:vw", "PMID:11283612", "PMID:15147268" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:28:30Z

false

true

7

GO:0097669

97,669

SCF-Skp2 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae.

[ "GOC:jd", "GOC:vw", "PMID:14747994" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:28:52Z

false

true

8

GO:0097670

97,670

SCF-Ufo1/Pof10 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe).

[ "GOC:jd", "GOC:vw", "PMID:14747994", "PMID:15147268" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:29:13Z

false

true

3

GO:0097671

97,671

SCF-YDR131C ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae.

[ "GOC:jd", "GOC:vw", "PMID:14747994" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:29:35Z

false

true

1

GO:0097672

97,672

SCF-Pof5 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae).

[ "GOC:jd", "GOC:vw", "PMID:14747994", "PMID:15147268" ]

null

[ "SCF-YDR306C ubiquitin ligase complex" ]

[ "RELATED" ]

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:30:10Z

false

true

3

GO:0097673

97,673

SCF-Ucc1 ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae.

[ "GOC:jd", "GOC:vw", "PMID:14747994", "PMID:25982115" ]

null

[ "SCF-YLR224W ubiquitin ligase complex" ]

[ "EXACT" ]

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:30:31Z

false

true

8

GO:0097674

97,674

SCF-YLR352W ubiquitin ligase complex

cellular_component

An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae.

[ "GOC:jd", "GOC:vw", "PMID:19882662" ]

null

[]

[ "GO:0019005" ]

[]

[ "GO:0019005" ]

[]

pr

2014-10-06T10:30:54Z

false

true

3

GO:0097676

97,676

obsolete histone H3-K36 dimethylation

biological_process

OBSOLETE. The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone.

[ "GOC:lb", "PMID:21187428" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

pr

2014-11-04T10:38:05Z

true

9

GO:0097677

97,677

STAT family protein binding

molecular_function

Binding to a member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell d...

[ "GOC:mr", "InterPro:IPR001217", "PMID:21447371", "PMID:24470978" ]

null

[ "signal transducers and activators of transcription family protein binding" ]

[ "EXACT" ]

[]

[ "GO:0061629" ]

[]

[ "GO:0061629" ]

[]

pr

2014-11-04T11:31:03Z

false

true

5

GO:0097678

97,678

SOCS family protein binding

molecular_function

Binding to a member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. ...

[ "GOC:mr", "InterPro:IPR028413", "PMID:23885323", "PMID:24705897" ]

null

[ "suppressor of cytokine signaling family protein binding" ]

[ "EXACT" ]

[]

[ "GO:0005515" ]

[]

[ "GO:0005515" ]

[]

pr

2014-11-04T11:32:49Z

false

true

8

GO:0097680

97,680

double-strand break repair via classical nonhomologous end joining

biological_process

An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).

[ "GOC:rph", "PMID:18584027" ]

null

[ "C-NHEJ", "canonical nonhomologous end joining" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0006303" ]

[]

[ "GO:0006303" ]

[]

pr

2014-12-17T15:15:18Z

false

true

3

GO:0097681

97,681

double-strand break repair via alternative nonhomologous end joining

biological_process

An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of non...

[ "GOC:rph", "PMID:18584027", "PMID:21655080", "Wikipedia:Microhomology-mediated_end_joining" ]

null

[ "A-NHEJ", "alt-NHEJ", "double-strand break repair via microhomology-mediated end joining", "MMEJ" ]

[ "RELATED", "RELATED", "EXACT", "RELATED" ]

[]

[ "GO:0006303" ]

[]

[ "GO:0006303" ]

[]

pr

2014-12-17T15:17:45Z

false

true

2

GO:0097682

97,682

intracellularly phosphatidylinositol-3,5-bisphosphate-gated monatomic cation channel activity

molecular_function

Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.

[ "GOC:ha", "PMID:24375408" ]

null

[ "intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity", "intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity" ]

[ "BROAD", "EXACT" ]

[]

[ "GO:0005217", "GO:0099094" ]

[]

[ "GO:0005217", "GO:0099094" ]

[]

pr

2014-12-17T16:50:30Z

false

true

2

GO:0097683

97,683

dinoflagellate apex

cellular_component

The anterior most point of a dinoflagellate epicone.

[ "GOC:at", "http://tolweb.org/Dinoflagellates/2445", "PMID:7002229", "Wikipedia:Dinoflagellate#Morphology" ]

The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.

[ "apex" ]

[ "BROAD" ]

[]

[ "GO:0110165" ]

[ "part_of GO:0097613" ]

[ "part_of" ]

[ "GO:0097613" ]

[ "GO:0097613", "GO:0110165" ]

[]

pr

2014-12-18T09:29:51Z

false

true

2

GO:0097684

97,684

dinoflagellate antapex

cellular_component

The anterior most point of a dinoflagellate hypocone.

[ "GOC:at", "http://tolweb.org/Dinoflagellates/2445", "Wikipedia:Dinoflagellate#Morphology" ]

The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.

[ "antapex" ]

[ "BROAD" ]

[]

[ "GO:0110165" ]

[ "part_of GO:0097614" ]

[ "part_of" ]

[ "GO:0097614" ]

[ "GO:0097614", "GO:0110165" ]

[]

pr

2014-12-18T09:32:10Z

false

true

6

GO:0097685

97,685

dinoflagellate apical groove

cellular_component

A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex.

[ "GOC:at", "http://tolweb.org/Dinoflagellates/2445", "PMID:20561119", "Wikipedia:Dinoflagellate#Morphology" ]

The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.

[ "apical groove" ]

[ "BROAD" ]

[]

[ "GO:0097610" ]

[ "part_of GO:0097613" ]

[ "part_of" ]

[ "GO:0097613" ]

[ "GO:0097610", "GO:0097613" ]

[]

pr

2014-12-18T09:34:52Z

false

true

1

GO:0097686

97,686

dinoflagellate apical horn

cellular_component

A horn-shaped dinoflagellate apex found in thecate species.

[ "GOC:at", "PMID:7002229" ]

null

[]

[ "GO:0097683" ]

[]

[ "GO:0097683" ]

[]

pr

2014-12-18T09:38:15Z

false

true

4

GO:0097687

97,687

dinoflagellate antapical horn

cellular_component

A horn-shaped dinoflagellate antapex found in thecate species.

[ "GOC:at", "PMID:7002229" ]

null

[]

[ "GO:0097684" ]

[]

[ "GO:0097684" ]

[]

pr

2014-12-18T09:39:57Z

false

true

6

GO:0097688

97,688

glutamate receptor clustering

biological_process

The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane.

[ "GOC:krc", "PMID:19723286" ]

null

[ "glutamatergic receptor clustering" ]

[ "EXACT" ]

[]

[ "GO:0072578" ]

[]

[ "GO:0072578" ]

[]

pr

2015-02-11T11:49:13Z

false

true

3

GO:0097690

97,690

iron ion transmembrane transporter inhibitor activity

molecular_function

Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter.

[ "GOC:BHF", "GOC:kom", "PMID:15514116" ]

An example of this is human hepcidin (UniProt symbol P81172), which regulates iron transport out of cells (see PMID:15514116).

[ "iron channel inhibitor activity" ]

[ "EXACT" ]

[]

[ "GO:0141110" ]

[ "negatively_regulates GO:0005381" ]

[ "negatively_regulates" ]

[ "GO:0005381" ]

[ "GO:0005381", "GO:0141110" ]

[]

null

false

true

2

GO:0097691

97,691

bacterial extracellular vesicle

cellular_component

Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells.

[ "GOC:aa", "PMID:25704309" ]

null

[]

[ "GO:1903561" ]

[]

[ "GO:1903561" ]

[]

pr

2015-09-24T11:31:44Z

false

true

2

GO:0097692

97,692

obsolete histone H3-K4 monomethylation

biological_process

OBSOLETE. The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone.

[ "GOC:jh2", "PMID:26320581" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

pr

2015-11-05T11:23:15Z

true

6

GO:0097693

97,693

ocelloid

cellular_component

Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastid...

[ "GOC:ar", "PMID:26131935" ]

null

[]

[ "GO:0043231" ]

[ "has_part GO:0005739", "has_part GO:0009536" ]

[ "has_part", "has_part" ]

[ "GO:0005739", "GO:0009536" ]

[ "GO:0005739", "GO:0009536", "GO:0043231" ]

[]

pr

2015-11-13T14:27:01Z

false

true

9

GO:0097694

97,694

establishment of RNA localization to telomere

biological_process

The directed movement of RNA to a specific location in the telomeric region of a chromosome.

[ "GOC:BHF", "GOC:BHF_telomere", "GOC:rph", "PMID:26586433" ]

null

[ "establishment of RNA localisation to telomere" ]

[ "EXACT" ]

[]

[ "GO:0051236" ]

[]

[ "GO:0051236" ]

[]

pr

2015-12-22T09:33:43Z

false

true

9

GO:0097695

97,695

establishment of protein-containing complex localization to telomere

biological_process

The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome.

[ "GOC:BHF", "GOC:BHF_telomere", "GOC:rph", "PMID:26586433" ]

null

[ "establishment of macromolecular complex localisation to telomere", "establishment of macromolecular complex localization to telomere" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0051234" ]

[ "part_of GO:0033036" ]

[ "part_of" ]

[ "GO:0033036" ]

[ "GO:0033036", "GO:0051234" ]

[]

pr

2015-12-22T09:38:13Z

false

true

5

GO:0097696

97,696

cell surface receptor signaling pathway via STAT

biological_process

An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA di...

[ "GOC:rjd", "PMID:21534947", "PMID:24587195" ]

In most species, STAT proteins are activated by members of the JAK (Janus Activated Kinase) family of tyrosine kinases; the term GO:0007259 'JAK-STAT cascade' describes this specificity. In other cases, such as D. discoideum, no JAK orthologs are known, and STAT proteins are activated by tyrosine kinase-like proteins.

[ "kinase activated-STAT cascade", "kinase-STAT cascade", "receptor signaling pathway via STAT", "STAT signalling pathway" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0007166" ]

[]

[ "GO:0007166" ]

[]

pr

2015-12-22T10:40:14Z

false

true

4

GO:0097697

97,697

tRNA (5-carboxymethoxyuridine(34)-5-O)-methyltransferase activity

molecular_function

Catalysis of the reaction: 5-carboxymethoxyuridine34 in tRNA + S-adenosyl-L-methionine = 5-methoxycarbonylmethoxyuridine34 in tRNA + S-adenosyl-L-homocysteine. The methylation occurs on the modified base.

[ "PMID:26681692", "RHEA:54080" ]

null

[ "tRNA 5-carboxymethoxyuridine methyltransferase activity" ]

[ "RELATED" ]

[]

[ "RHEA:54080" ]

[ "GO:0016300" ]

[]

[ "GO:0016300" ]

[]

[ "skos:exactMatch RHEA:54080", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26117\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pr

2016-01-07T10:36:46Z

false

true

3

GO:0097700

97,700

vascular endothelial cell response to laminar fluid shear stress

biological_process

Any response to laminar fluid shear stress in a vascular endothelial cell.

[ "GOC:bc", "GOC:BHF", "GOC:BHF_miRNA", "PMID:21768538" ]

null

[ "blood vessel endothelial cell response to laminar fluid shear stress" ]

[ "EXACT" ]

[]

[ "Reactome:R-HSA-9856530 \"High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells\"" ]

[ "GO:0071499", "GO:0097699" ]

[]

[ "GO:0071499", "GO:0097699" ]

[]

pr

2016-01-27T12:42:01Z

false

true

2

GO:0097701

97,701

response to pulsatile fluid shear stress

biological_process

Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhanc...

[ "GOC:bc", "GOC:BHF", "GOC:BHF_miRNA", "PMID:21768538" ]

null

[]

[ "GO:0034405" ]

[]

[ "GO:0034405" ]

[]

pr

2016-01-27T14:13:31Z

false

true

6

GO:0097703

97,703

cellular response to pulsatile fluid shear stress

biological_process

Any response to pulsatile fluid shear stress that occurs at the level of a cell.

[ "GOC:bc", "GOC:BHF", "GOC:BHF_miRNA", "PMID:21768538" ]

null

[]

[ "GO:0071498", "GO:0097701" ]

[]

[ "GO:0071498", "GO:0097701" ]

[]

pr

2016-01-27T14:18:23Z

false

true

6

GO:0097704

97,704

cellular response to oscillatory fluid shear stress

biological_process

Any response to oscillatory fluid shear stress that occurs at the level of a cell.

[ "GOC:bc", "GOC:BHF", "GOC:BHF_miRNA", "PMID:21768538" ]

null

[]

[ "GO:0071498", "GO:0097702" ]

[]

[ "GO:0071498", "GO:0097702" ]

[]

pr

2016-01-27T14:20:54Z

false

true

2

GO:0097705

97,705

vascular endothelial cell response to pulsatile fluid shear stress

biological_process

Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell.

[ "GOC:bc", "GOC:BHF", "GOC:BHF_miRNA", "PMID:21768538" ]

null

[ "blood vessel endothelial cell response to pulsatile fluid shear stress" ]

[ "EXACT" ]

[]

[ "GO:0097699", "GO:0097703" ]

[]

[ "GO:0097699", "GO:0097703" ]

[]

pr

2016-01-27T14:22:44Z

false

true

1

GO:0097707

97,707

ferroptosis

biological_process

A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-act...

[ "GOC:mtg_apoptosis", "PMID:25236395", "PMID:26794443" ]

null

[ "iron-dependent programmed cell death" ]

[ "RELATED" ]

[]

[ "GO:0012501" ]

[]

[ "GO:0012501" ]

[]

pr

2016-03-03T12:51:18Z

false

true

2

GO:0097708

97,708

intracellular vesicle

cellular_component

Any vesicle that is part of the intracellular region.

[ "GOC:vesicles" ]

null

[]

[ "GO:0031982", "GO:0043231" ]

[]

[ "GO:0031982", "GO:0043231" ]

[ "GO:0031982", "part_of GO:0005622" ]

[]

pr

2016-03-29T17:39:45Z

false

true

3

GO:0097709

97,709

connective tissue replacement

biological_process

The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared.

[ "GOC:bc", "GOC:BHF", "GOC:BHF_miRNA", "PMID:25590961" ]

null

[]

[ "GO:0048771" ]

[]

[ "GO:0048771" ]

[]

pr

2016-05-17T10:49:10Z

false

true

2

GO:0097710

97,710

viral terminase, small subunit

cellular_component

The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit.

[ "GOC:ch", "GOC:jh2", "PMID:18687036" ]

This term should only be used when the small subunit consists of more than one polypeptide.

[ "virus terminase, small subunit" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0043493" ]

[ "part_of" ]

[ "GO:0043493" ]

[ "GO:0032991", "GO:0043493" ]

[]

pr

2016-06-07T12:45:00Z

false

true

7

GO:0097711

97,711

ciliary basal body-plasma membrane docking

biological_process

The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by...

[ "GOC:cilia", "PMID:13978319", "PMID:23348840", "PMID:23530209", "PMID:25686250", "PMID:26981235" ]

Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through...

[ "anchoring of the basal body to the plasma membrane", "ciliary basal body docking" ]

[ "RELATED", "EXACT" ]

[]

[ "Reactome:R-HSA-5620912 \"Anchoring of the basal body to the plasma membrane\"" ]

[ "GO:0140056" ]

[ "part_of GO:0060271" ]

[ "part_of" ]

[ "GO:0060271" ]

[ "GO:0060271", "GO:0140056" ]

[]

pr

2016-08-05T16:12:33Z

false

true

4

GO:0097712

97,712

vesicle targeting, trans-Golgi to periciliary membrane compartment

biological_process

The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.

[ "GOC:cilia", "PMID:20106869", "PMID:23351793", "PMID:24814148", "PMID:26485645" ]

null

[]

[ "GO:0048199" ]

[ "part_of GO:0060271" ]

[ "part_of" ]

[ "GO:0060271" ]

[ "GO:0048199", "GO:0060271" ]

[]

pr

2016-08-05T16:16:28Z

false

true

5

GO:0097713

97,713

dolichol-phosphate-mannose synthase regulator activity

molecular_function

Binds to and modulates the activity of dolichol-phosphate-mannose synthase.

[ "GOC:vw", "PMID:10835346" ]

null

[]

[ "GO:0030234" ]

[ "regulates GO:0004169" ]

[ "regulates" ]

[ "GO:0004169" ]

[ "GO:0004169", "GO:0030234" ]

[]

pr

2016-08-23T11:19:37Z

false

true

4

GO:0097714

97,714

response to viscosity

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.

[ "GOC:sl", "PMID:7061416" ]

null

[]

[ "GO:0009628" ]

[]

[ "GO:0009628" ]

[]

pr

2016-08-23T14:32:46Z

false

true

1

GO:0097715

97,715

cellular response to viscosity

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.

[ "GOC:sl", "PMID:7061416" ]

null

[]

[ "GO:0071214", "GO:0097714" ]

[]

[ "GO:0071214", "GO:0097714" ]

[]

pr

2016-08-23T14:34:05Z

false

true

8

GO:0097716

97,716

copper ion transport across blood-brain barrier

biological_process

The directed movement of copper (Cu) ions passing through the blood-brain barrier.

[ "GOC:sl", "PMID:24614235" ]

null

[ "copper ion transport across BBB" ]

[ "RELATED" ]

[]

[ "GO:0006825", "GO:0150104" ]

[]

[ "GO:0006825", "GO:0150104" ]

[]

pr

2016-08-23T14:35:54Z

false

true

8

GO:0097717

97,717

copper ion transport across blood-cerebrospinal fluid barrier

biological_process

The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier.

[ "GOC:sl", "PMID:24614235" ]

null

[ "copper ion transport across BCB", "copper ion transport across BCSFB", "copper ion transport across blood-CSF barrier", "copper ion transport across blood/cerebrospinal fluid barrier", "copper ion transport across blood/CSF barrier" ]

[ "RELATED", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006825", "GO:0150195" ]

[]

[ "GO:0006825", "GO:0150195" ]

[]

pr

2016-08-23T14:37:33Z

false

true

3

GO:0097718

97,718

disordered domain specific binding

molecular_function

Binding to a disordered domain of a protein.

[ "GOC:gg", "PMID:11746698" ]

null

[ "disordered protein domain specific binding" ]

[ "RELATED" ]

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

pr

2016-08-23T16:42:51Z

false

true

5

GO:0097719

97,719

neural tissue regeneration

biological_process

The regrowth of neural tissue following its loss or destruction.

[ "Wikipedia:Neuroregeneration" ]

null

[ "neuroregeneration" ]

[ "RELATED" ]

[]

[ "GO:0042246" ]

[]

[ "GO:0042246" ]

[]

pr

2016-08-25T13:14:27Z

false

true

3

GO:0097720

97,720

calcineurin-mediated signaling

biological_process

Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodu...

[ "GOC:di", "PMID:25655284", "PMID:25878052", "PMID:26851544" ]

null

[ "calcineurin signaling", "calcineurin-mediated signalling" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0019722" ]

[]

[ "GO:0019722" ]

[]

pr

2016-08-25T15:22:21Z

false

true

1

GO:0097721

97,721

ciliary vesicle

cellular_component

A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicle...

[ "GOC:cilia", "PMID:13978319", "PMID:25686250" ]

null

[ "CV", "primary ciliary vesicle" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0031410" ]

[]

[ "GO:0031410" ]

[]

pr

2016-08-30T13:54:38Z

false

true

2

GO:0097723

97,723

amoeboid sperm motility

biological_process

Any process involved in the controlled movement of an amoeboid sperm cell.

[ "GOC:cilia", "GOC:krc" ]

null

[ "ameboid sperm motility", "ameboid sperm movement", "amoeboid sperm movement" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0097722" ]

[]

[ "GO:0097722" ]

[]

pr

2016-09-01T12:02:19Z

false

true

4

GO:0097725

97,725

obsolete histone H3-K79 dimethylation

biological_process

OBSOLETE. The modification of histone H3 by addition of two methyl groups to lysine at position 79 of the histone.

[ "GOC:hbye", "PMID:27541139" ]

This term was obsoleted because it represents a molecular function.

[ "histone H3 K79 dimethylation", "histone lysine H3 K79 dimethylation" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0031151" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24261\" xsd:anyURI" ]

pr

2016-09-15T12:41:13Z

true

3

GO:0097726

97,726

LEM domain binding

molecular_function

Binding to a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF).

[ "GOC:rz", "InterPro:IPR003887", "PMID:22399800" ]

null

[ "lamina-associated polypeptide, emerin, MAN1 domain binding", "LAP2, emerin, MAN1 domain binding" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

pr

2016-09-19T10:19:02Z

false

true

7

GO:0097727

97,727

blepharoplast

cellular_component

An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles,...

[ "GOC:cilia", "GOC:tb", "PMID:22691130", "PMID:25047614" ]

The blepharoplast should not be confused with a basal body; rather, it acts as the precursor assembly zone for multiple basal bodies.

[]

[ "GO:0043232" ]

[]

[ "GO:0043232" ]

[]

pr

2016-09-23T10:57:18Z

false

true

5

GO:0097728

97,728

9+0 motile cilium

cellular_component

A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).

[ "GOC:cilia", "PMID:10330409", "PMID:22118931" ]

This type of cilia may be present in solitary (classic nodal cilia in embryonic nodes) or in multiple copies (e.g. in the choroid plexus epithelium).

[ "motile 9+0 cilium", "nodal cilium" ]

[ "EXACT", "NARROW" ]

[]

[ "GO:0031514" ]

[ "has_part GO:0036156", "has_part GO:0036157", "has_part GO:0097545" ]

[ "has_part", "has_part", "has_part" ]

[ "GO:0036156", "GO:0036157", "GO:0097545" ]

[ "GO:0031514", "GO:0036156", "GO:0036157", "GO:0097545" ]

[]

pr

2016-09-27T15:24:37Z

false

true

2

GO:0097729

97,729

9+2 motile cilium

cellular_component

A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).

[ "GOC:cilia", "PMID:22118931" ]

This type of cilia may be present in solitary (so-called flagella, e.g. in sperm) or in multiple copies (so-called conventional motile cilia, e.g. in tracheal epithelium, ependyma or oviduct epithelium).

[ "conventional motile cilium", "motile 9+2 cilium", "sperm flagellum" ]

[ "NARROW", "EXACT", "NARROW" ]

[]

[ "GO:0031514" ]

[ "has_part GO:0001534", "has_part GO:0036156", "has_part GO:0036157", "has_part GO:0097540", "has_part GO:0097545" ]

[ "has_part", "has_part", "has_part", "has_part", "has_part" ]

[ "GO:0001534", "GO:0036156", "GO:0036157", "GO:0097540", "GO:0097545" ]

[ "GO:0001534", "GO:0031514", "GO:0036156", "GO:0036157", "GO:0097540", "GO:0097545" ]

[]

pr

2016-09-27T15:26:34Z

false

true

4

GO:0097730

97,730

non-motile cilium

cellular_component

A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.

[ "GOC:cilia", "GOC:dgh", "GOC:kmv", "PMID:17009929", "PMID:20144998", "PMID:22118931" ]

null

[ "immotile cilium", "immotile primary cilium", "nonmotile cilium", "nonmotile primary cilia", "nonmotile primary cilium", "sensory cilium" ]

[ "EXACT", "RELATED", "EXACT", "RELATED", "RELATED", "RELATED" ]

[ "GO:0031513" ]

[]

[ "GO:0005929" ]

[]

[ "GO:0005929" ]

[]

pr

2016-09-29T14:02:11Z

false

true

4

GO:0097731

97,731

9+0 non-motile cilium

cellular_component

A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).

[ "GOC:cilia", "PMID:22118931" ]

This type of cilia may be present in solitary (authentic primary cilia in many cell types) or in multiple copies (e.g. in Grueneberg ganglion neurons).

[ "9+0 immotile cilium", "non-motile 9+0 cilium", "primary cilium" ]

[ "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:0097730" ]

[]

[ "GO:0097730" ]

[]

pr

2016-09-29T14:05:03Z

false

true

3

GO:0097732

97,732

9+2 non-motile cilium

cellular_component

A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).

[ "GOC:cilia", "PMID:21307074", "PMID:22118931" ]

This type of cilia may be present in solitary (e.g. in inner hair cells) or in multiple copies (e.g. in olfactory neurons).

[ "9+2 immotile cilium", "non-motile 9+2 cilium" ]

[ "RELATED", "EXACT" ]

[]

[ "GO:0097730" ]

[ "has_part GO:0036157" ]

[ "has_part" ]

[ "GO:0036157" ]

[ "GO:0036157", "GO:0097730" ]

[]

pr

2016-09-29T14:07:33Z

false

true

7

GO:0097733

97,733

photoreceptor cell cilium

cellular_component

A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment.

[ "GOC:cilia", "Wikipedia:Photoreceptor_cell#Histology" ]

null

[ "photoreceptor cilium" ]

[ "EXACT" ]

[]

[ "GO:0043005", "GO:0097731" ]

[]

[ "GO:0043005", "GO:0097731" ]

[]

pr

2016-09-30T10:50:11Z

false

true

2

GO:0097734

97,734

extracellular exosome biogenesis

biological_process

The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.

[ "GOC:bf", "GOC:PARL", "PMID:19442504", "PMID:25392495" ]

null

[ "exosome assembly or secretion", "exosome biogenesis", "exosome production", "ILV assembly", "intraluminal vesicle assembly" ]

[ "EXACT", "EXACT", "EXACT", "RELATED", "RELATED" ]

[]

[ "GO:0140112" ]

[]

[ "GO:0140112" ]

[]

pr

2016-10-03T14:35:25Z

false

true

6

GO:0097735

97,735

DIM/DIP cell wall layer

cellular_component

A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds.

[ "GOC:pr" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0009275" ]

[ "part_of" ]

[ "GO:0009275" ]

[ "GO:0009275", "GO:0110165" ]

[]

pr

2016-10-05T14:55:30Z

false

true

4

GO:0097736

97,736

aerial mycelium formation

biological_process

The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aer...

[ "GOC:di", "PMID:12832397" ]

null

[ "aerial hyphal growth", "fertile mycelium formation" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0048856" ]

[ "part_of GO:0019954" ]

[ "part_of" ]

[ "GO:0019954" ]

[ "GO:0019954", "GO:0048856" ]

[]

pr

2016-10-14T14:25:22Z

false

true

2

GO:0097738

97,738

substrate mycelium formation

biological_process

The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate.

[ "GOC:di", "PMID:10021365" ]

null

[]

[ "GO:0048856" ]

[ "part_of GO:0019954" ]

[ "part_of" ]

[ "GO:0019954" ]

[ "GO:0019954", "GO:0048856" ]

[]

pr

2016-10-18T16:21:05Z

false

true

9

GO:0097739

97,739

negative regulation of ferrichrome biosynthetic process in response to iron

biological_process

Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus.

[ "GOC:al" ]

null

[]

[ "GO:1905569" ]

[ "part_of GO:0071281" ]

[ "part_of" ]

[ "GO:0071281" ]

[ "GO:0071281", "GO:1905569" ]

[]

pr

2016-10-18T17:00:24Z

false

true

5

GO:0097740

97,740

paraflagellar rod

cellular_component

A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signaling and metabolism, and in calcium signaling.

[ "GOC:cilia", "PMID:19879876", "PMID:26199333", "PMID:26688619" ]

null

[ "PFR" ]

[ "RELATED" ]

[]

[ "GO:0099080" ]

[ "part_of GO:0097729" ]

[ "part_of" ]

[ "GO:0097729" ]

[ "GO:0097729", "GO:0099080" ]

[]

pr

2016-10-19T11:30:08Z

false

true

9

GO:0097741

97,741

mastigoneme

cellular_component

A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by incr...

[ "GOC:cilia", "PMID:943397", "Wikipedia:Mastigoneme" ]

null

[]

[ "GO:0099080" ]

[ "part_of GO:0031514" ]

[ "part_of" ]

[ "GO:0031514" ]

[ "GO:0031514", "GO:0099080" ]

[]

pr

2016-10-19T11:33:38Z

false

true

3