go_id string | go_numeric_id int64 | name string | namespace string | definition string | definition_xrefs list | comment string | synonyms list | synonym_scopes list | alt_ids list | subsets list | xrefs list | is_a_ids list | relationship_edges list | relationship_types list | relationship_target_ids list | parent_ids list | intersection_of list | union_of list | disjoint_from list | replaced_by list | consider list | property_values list | created_by string | creation_date string | is_obsolete bool | in_go_basic bool | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GO:0099548 | 99,548 | trans-synaptic signaling by nitric oxide | biological_process | Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099163",
"GO:0099543"
] | [] | [] | [] | [
"GO:0099163",
"GO:0099543"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099549 | 99,549 | trans-synaptic signaling by carbon monoxide | biological_process | Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099543"
] | [] | [] | [] | [
"GO:0099543"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099550 | 99,550 | trans-synaptic signaling, modulating synaptic transmission | biological_process | Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0050804",
"GO:0099537"
] | [] | [] | [] | [
"GO:0050804",
"GO:0099537"
] | [
"GO:0099537",
"regulates GO:0007268"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099551 | 99,551 | trans-synaptic signaling by neuropeptide, modulating synaptic transmission | biological_process | Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099540",
"GO:0099550"
] | [] | [] | [] | [
"GO:0099540",
"GO:0099550"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0099552 | 99,552 | trans-synaptic signaling by lipid, modulating synaptic transmission | biological_process | Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. | [
"GOC:dos",
"PMID:21531987"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099541",
"GO:0099550"
] | [] | [] | [] | [
"GO:0099541",
"GO:0099550"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0099553 | 99,553 | trans-synaptic signaling by endocannabinoid, modulating synaptic transmission | biological_process | Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse. | [
"GOC:dos",
"PMID:21531987"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099542",
"GO:0099552"
] | [] | [] | [] | [
"GO:0099542",
"GO:0099552"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099554 | 99,554 | trans-synaptic signaling by soluble gas, modulating synaptic transmission | biological_process | Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099543",
"GO:0099550"
] | [] | [] | [] | [
"GO:0099543",
"GO:0099550"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0099555 | 99,555 | trans-synaptic signaling by nitric oxide, modulating synaptic transmission | biological_process | Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099548",
"GO:0099554"
] | [] | [] | [] | [
"GO:0099548",
"GO:0099554"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099556 | 99,556 | trans-synaptic signaling by carbon monoxide, modulating synaptic transmission | biological_process | Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099549",
"GO:0099554"
] | [] | [] | [] | [
"GO:0099549",
"GO:0099554"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0099557 | 99,557 | trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission | biological_process | Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse. | [
"GOC:dos",
"PMID:19029886"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099545",
"GO:0099550"
] | [] | [] | [] | [
"GO:0099545",
"GO:0099550"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099558 | 99,558 | maintenance of synapse structure | biological_process | A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds. | [
"GOC:dos",
"PMID:24449494",
"PMID:25611509"
] | null | [
"synaptic maintenance"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0034331",
"GO:0050808"
] | [] | [] | [] | [
"GO:0034331",
"GO:0050808"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099559 | 99,559 | maintenance of alignment of postsynaptic density and presynaptic active zone | biological_process | The process by which alignment between postsynaptic density and presynaptic active zone is maintained. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099558"
] | [] | [] | [] | [
"GO:0099558"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099560 | 99,560 | synaptic membrane adhesion | biological_process | The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane. | [
"GOC:dos"
] | null | [
"synapse adhesion between pre- and post-synapse"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0098609"
] | [
"part_of GO:0050808"
] | [
"part_of"
] | [
"GO:0050808"
] | [
"GO:0050808",
"GO:0098609"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099561 | 99,561 | synaptic membrane adhesion to extracellular matrix | biological_process | The binding of a synaptic membrane to the extracellular matrix via adhesion molecules. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0007160"
] | [
"part_of GO:0050808"
] | [
"part_of"
] | [
"GO:0050808"
] | [
"GO:0007160",
"GO:0050808"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0099562 | 99,562 | maintenance of postsynaptic density structure | biological_process | A process which maintains the organization and the arrangement of proteins in the presynaptic density. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0098880"
] | [] | [] | [] | [
"GO:0098880"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099563 | 99,563 | modification of synaptic structure | biological_process | Any process that modifies the structure/morphology of a synapse. | [
"GOC:dos"
] | This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones. | [
"synapse remodelling"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0050808"
] | [] | [] | [] | [
"GO:0050808"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0099564 | 99,564 | modification of synaptic structure, modulating synaptic transmission | biological_process | Any process that modulates synaptic transmission via modification of the structure of the synapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099563"
] | [
"regulates GO:0007268"
] | [
"regulates"
] | [
"GO:0007268"
] | [
"GO:0007268",
"GO:0099563"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0099565 | 99,565 | chemical synaptic transmission, postsynaptic | biological_process | The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. | [
"GOC:dos"
] | null | [
"postsynaptic process involved in chemical synaptic transmission"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0007166",
"GO:0050877"
] | [
"occurs_in GO:0098794",
"part_of GO:0007268"
] | [
"occurs_in",
"part_of"
] | [
"GO:0098794",
"GO:0007268"
] | [
"GO:0007166",
"GO:0007268",
"GO:0050877",
"GO:0098794"
] | [
"GO:0007166",
"occurs_in GO:0098794",
"part_of GO:0007268"
] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099566 | 99,566 | regulation of postsynaptic cytosolic calcium ion concentration | biological_process | Any process that regulates the concentration of calcium in the postsynaptic cytosol. | [
"GOC:dos"
] | null | [
"regulation of postsynaptic cytosolic calcium levels"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0051480"
] | [
"occurs_in GO:0098794"
] | [
"occurs_in"
] | [
"GO:0098794"
] | [
"GO:0051480",
"GO:0098794"
] | [
"GO:0051480",
"occurs_in GO:0098794"
] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099567 | 99,567 | calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration | molecular_function | The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations. | [
"PMID:24442513",
"PMID:26190970"
] | null | [
"calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels",
"postsynaptic calcium ion buffering",
"regulation of postsynaptic cytosolic calcium ion concentration by calcium ion buffering"
] | [
"EXACT",
"EXACT",
"RELATED"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0005509"
] | [
"occurs_in GO:0099524",
"part_of GO:0099566"
] | [
"occurs_in",
"part_of"
] | [
"GO:0099524",
"GO:0099566"
] | [
"GO:0005509",
"GO:0099524",
"GO:0099566"
] | [
"GO:0005509",
"part_of GO:0099566"
] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099568 | 99,568 | cytoplasmic region | cellular_component | Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. | [
"GOC:dos"
] | null | [] | [] | [] | [
"gocheck_do_not_annotate"
] | [] | [
"GO:0005737"
] | [] | [] | [] | [
"GO:0005737"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31276\" xsd:anyURI"
] | null | null | false | true | 2 |
GO:0099569 | 99,569 | presynaptic cytoskeleton | cellular_component | The portion of the cytoskeleton contained within the presynapse. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0005856"
] | [
"part_of GO:0098793"
] | [
"part_of"
] | [
"GO:0098793"
] | [
"GO:0005856",
"GO:0098793"
] | [
"GO:0005856",
"part_of GO:0098793"
] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0099571 | 99,571 | postsynaptic cytoskeleton | cellular_component | The portion of the cytoskeleton contained within the postsynapse. | [
"GOC:dos",
"PMID:19889835"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0005856"
] | [
"part_of GO:0098794"
] | [
"part_of"
] | [
"GO:0098794"
] | [
"GO:0005856",
"GO:0098794"
] | [
"GO:0005856",
"part_of GO:0098794"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099572 | 99,572 | postsynaptic specialization | cellular_component | A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. | [
"PMID:22046028"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0043226"
] | [
"part_of GO:0098794"
] | [
"part_of"
] | [
"GO:0098794"
] | [
"GO:0043226",
"GO:0098794"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099573 | 99,573 | glutamatergic postsynaptic density | cellular_component | The post-synaptic specialization of a glutamatergic excitatory synapse. | [
"GOC:dos"
] | null | [
"postsynaptic specialization, glutamatergic neuron-to-neuron synapse"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0014069"
] | [] | [] | [] | [
"GO:0014069"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099574 | 99,574 | regulation of protein catabolic process at synapse, modulating synaptic transmission | biological_process | Any process that modulates synaptic transmission by regulating protein degradation at the synapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0050804",
"GO:0140250"
] | [] | [] | [] | [
"GO:0050804",
"GO:0140250"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099575 | 99,575 | regulation of protein catabolic process at presynapse, modulating synaptic transmission | biological_process | Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0042176",
"GO:0099171"
] | [] | [] | [] | [
"GO:0042176",
"GO:0099171"
] | [
"GO:0042176",
"occurs_in GO:0098793",
"regulates GO:0007268"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099577 | 99,577 | regulation of translation at presynapse, modulating synaptic transmission | biological_process | Any process that modulates synaptic transmission by regulating translation occurring at the presynapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099171",
"GO:0099547",
"GO:0140244"
] | [] | [] | [] | [
"GO:0099171",
"GO:0099547",
"GO:0140244"
] | [
"GO:0065007",
"occurs_in GO:0098793",
"regulates GO:0006412",
"regulates GO:0007268"
] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099578 | 99,578 | regulation of translation at postsynapse, modulating synaptic transmission | biological_process | Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse. | [
"GOC:dos"
] | Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099170",
"GO:0099547",
"GO:0140245"
] | [] | [] | [] | [
"GO:0099170",
"GO:0099547",
"GO:0140245"
] | [
"GO:0065007",
"occurs_in GO:0098794",
"regulates GO:0006412",
"regulates GO:0007268"
] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099579 | 99,579 | obsolete G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | molecular_function | OBSOLETE. A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential. | [
"GOC:dos"
] | The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model. | [
"G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0099528"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31205\" xsd:anyURI"
] | null | null | true | true | 8 |
GO:0099580 | 99,580 | obsolete monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential | molecular_function | OBSOLETE. Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential. | [
"GOC:dos"
] | This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model. | [
"ion antiporter activity involved in regulation of post-synaptic membrane potential",
"ion antiporter activity involved in regulation of postsynaptic membrane potential"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24479\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI"
] | null | null | true | true | 2 |
GO:0099581 | 99,581 | obsolete ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential | molecular_function | OBSOLETE. Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential. | [
"GOC:dos"
] | The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model. | [
"ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential",
"ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0042625"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31205\" xsd:anyURI"
] | null | null | true | true | 2 |
GO:0099582 | 99,582 | obsolete neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration | molecular_function | OBSOLETE. Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol. | [
"GOC:dos"
] | This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model. | [
"neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0030594",
"GO:0099509"
] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI"
] | null | null | true | true | 2 |
GO:0099583 | 99,583 | obsolete neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration | molecular_function | OBSOLETE. Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol. | [
"GOC:dos"
] | This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model. | [
"neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels"
] | [
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI"
] | null | null | true | true | 3 |
GO:0099585 | 99,585 | release of sequestered calcium ion into presynaptic cytosol | biological_process | The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0051209",
"GO:0051649"
] | [
"occurs_in GO:0098793"
] | [
"occurs_in"
] | [
"GO:0098793"
] | [
"GO:0051209",
"GO:0051649",
"GO:0098793"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099586 | 99,586 | release of sequestered calcium ion into postsynaptic cytosol | biological_process | The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0051209",
"GO:0051649"
] | [
"occurs_in GO:0098794"
] | [
"occurs_in"
] | [
"GO:0098794"
] | [
"GO:0051209",
"GO:0051649",
"GO:0098794"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0099587 | 99,587 | inorganic ion import across plasma membrane | biological_process | The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol. | [
"GOC:dos"
] | null | [
"inorganic ion import into cell"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0098739"
] | [] | [] | [] | [
"GO:0098739"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099588 | 99,588 | positive regulation of postsynaptic cytosolic calcium concentration | biological_process | Any process that increases the concentration of calcium ions in the postsynaptic cytosol. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0007204"
] | [
"occurs_in GO:0098794"
] | [
"occurs_in"
] | [
"GO:0098794"
] | [
"GO:0007204",
"GO:0098794"
] | [
"GO:0007204",
"occurs_in GO:0098794"
] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0099589 | 99,589 | serotonin receptor activity | molecular_function | Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0004888"
] | [] | [] | [] | [
"GO:0004888"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099590 | 99,590 | neurotransmitter receptor internalization | biological_process | A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0031623"
] | [] | [] | [] | [
"GO:0031623"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099592 | 99,592 | endocytosed synaptic vesicle processing via endosome | biological_process | The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles. | [
"GOC:dos"
] | null | [
"synaptic vesicle processing via endosome involved in synaptic vesicle recycling"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0099003",
"GO:0099532"
] | [
"part_of GO:0036466"
] | [
"part_of"
] | [
"GO:0036466"
] | [
"GO:0036466",
"GO:0099003",
"GO:0099532"
] | [
"GO:0099532",
"part_of GO:0036466"
] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099593 | 99,593 | endocytosed synaptic vesicle to endosome fusion | biological_process | Fusion of an endocytosed synaptic vesicle with an endosome. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0016189"
] | [
"part_of GO:0036466"
] | [
"part_of"
] | [
"GO:0036466"
] | [
"GO:0016189",
"GO:0036466"
] | [
"GO:0016189",
"part_of GO:0036466"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099601 | 99,601 | regulation of neurotransmitter receptor activity | biological_process | Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors. | [
"GOC:dos"
] | null | [] | [] | [] | [
"gocheck_obsoletion_candidate",
"goslim_synapse"
] | [] | [
"GO:0010469"
] | [
"regulates GO:0030594"
] | [
"regulates"
] | [
"GO:0030594"
] | [
"GO:0010469",
"GO:0030594"
] | [
"GO:0065007",
"regulates GO:0030594"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099602 | 99,602 | neurotransmitter receptor regulator activity | molecular_function | A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing. | [
"GOC:dos",
"PMID:12740117",
"PMID:18387948"
] | null | [] | [] | [] | [] | [] | [
"GO:0030545"
] | [
"regulates GO:0030594"
] | [
"regulates"
] | [
"GO:0030594"
] | [
"GO:0030545",
"GO:0030594"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099604 | 99,604 | ligand-gated calcium channel activity | molecular_function | Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [
"Reactome:R-HSA-1168376 \"STIM1 oligomerizes\"",
"Reactome:R-HSA-169680 \"IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel\"",
"Reactome:R-HSA-169683 \"IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol\"",
"Reactome:R-HSA-4420052 \"Decreasing cGMP concentration pro... | [
"GO:0005262",
"GO:0099094"
] | [
"part_of GO:0019722"
] | [
"part_of"
] | [
"GO:0019722"
] | [
"GO:0005262",
"GO:0019722",
"GO:0099094"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099605 | 99,605 | regulation of action potential firing rate | biological_process | Any process that regulates the frequency of action potentials in a spike train. | [
"ISBN:978-0071390118"
] | null | [] | [] | [] | [] | [] | [
"GO:0098900"
] | [] | [] | [] | [
"GO:0098900"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099606 | 99,606 | microtubule plus-end directed mitotic chromosome migration | biological_process | The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression. | [
"GOC:dos",
"PMID:26258632",
"PMID:26705896"
] | null | [
"plus-end directed chromosome gliding"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0007018",
"GO:0050000",
"GO:0051649",
"GO:0051656",
"GO:1903047"
] | [
"part_of GO:0007080"
] | [
"part_of"
] | [
"GO:0007080"
] | [
"GO:0007018",
"GO:0007080",
"GO:0050000",
"GO:0051649",
"GO:0051656",
"GO:1903047"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099607 | 99,607 | lateral attachment of mitotic spindle microtubules to kinetochore | biological_process | The cellular process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate). | [
"PMID:26258632",
"PMID:26705896"
] | null | [] | [] | [] | [] | [] | [
"GO:0051315"
] | [] | [] | [] | [
"GO:0051315"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099608 | 99,608 | regulation of action potential firing pattern | biological_process | Any process that regulates the temporal pattern of a sequence of action potentials in a neuron. | [
"ISBN:978-0071390118"
] | null | [
"spike train sculpting"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0098900"
] | [
"regulates GO:0098874"
] | [
"regulates"
] | [
"GO:0098874"
] | [
"GO:0098874",
"GO:0098900"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099609 | 99,609 | microtubule lateral binding | molecular_function | Binding to the side of a microtubule. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0008017"
] | [] | [] | [] | [
"GO:0008017"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 7 |
GO:0099610 | 99,610 | action potential initiation | biological_process | The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate. | [
"ISBN:978-0071390118",
"PMID:19439602"
] | null | [
"action potential firing",
"action potential triggering"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0001508"
] | [] | [] | [] | [
"GO:0001508"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099611 | 99,611 | regulation of action potential firing threshold | biological_process | Any process that regulates the potential at which an axon potential is triggered. | [
"ISBN:978-0071390118"
] | null | [] | [] | [] | [] | [] | [
"GO:0098900"
] | [] | [] | [] | [
"GO:0098900"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099612 | 99,612 | protein localization to axon | biological_process | A process in which a protein is transported to or maintained in a location within an axon. | [
"GOC:dos",
"PMID:26157139"
] | null | [] | [] | [] | [] | [] | [
"GO:0008104"
] | [] | [] | [] | [
"GO:0008104"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099613 | 99,613 | protein localization to cell wall | biological_process | The process of directing proteins towards the cell-wall. | [
"ISBN:0716731363"
] | null | [] | [] | [] | [] | [] | [
"GO:0008104",
"GO:0071692"
] | [] | [] | [] | [
"GO:0008104",
"GO:0071692"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099616 | 99,616 | extrinsic component of matrix side of mitochondrial inner membrane | cellular_component | The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0031314"
] | [
"part_of GO:0099617"
] | [
"part_of"
] | [
"GO:0099617"
] | [
"GO:0031314",
"GO:0099617"
] | [
"GO:0019898",
"part_of GO:0099617"
] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099617 | 99,617 | matrix side of mitochondrial inner membrane | cellular_component | The leaflet of a mitochondrial inner membrane that faces the matrix, including any protein embedded in, attached to, or peripherally associated with it. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0098576"
] | [
"part_of GO:0005743"
] | [
"part_of"
] | [
"GO:0005743"
] | [
"GO:0005743",
"GO:0098576"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31515\" xsd:anyURI"
] | null | null | false | true | 1 |
GO:0099618 | 99,618 | UDP-glucuronate dehydrogenase activity | molecular_function | Catalysis of the reaction: UDP-alpha-D-glucuronate + NAD+ = UDP-beta-L-threo-pentopyranos-4-ulose + CO2 + NADH. | [
"RHEA:24702"
] | null | [
"UDP-GlcUA decarboxylase activity",
"UDP-glucuronic acid dehydrogenase activity"
] | [
"EXACT",
"EXACT"
] | [] | [] | [
"EC:1.1.1.305",
"MetaCyc:RXN0-1861",
"RHEA:24702"
] | [
"GO:0016616"
] | [] | [] | [] | [
"GO:0016616"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:1.1.1.305",
"skos:exactMatch MetaCyc:RXN0-1861",
"skos:exactMatch RHEA:24702",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29382\" xsd:anyURI"
] | null | null | false | true | 6 |
GO:0099619 | 99,619 | UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity | molecular_function | Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose. | [
"PMID:15695810",
"PMID:15807526",
"PMID:15809294",
"PMID:15939024",
"PMID:17928292"
] | null | [
"10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity",
"ArnAFT activity",
"UDP-L-Ara4N formyltransferase activity"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"EC:2.1.2.13",
"RHEA:24706"
] | [
"GO:0016742"
] | [] | [] | [] | [
"GO:0016742"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:2.1.2.13",
"skos:exactMatch RHEA:24706",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI"
] | null | null | false | true | 3 |
GO:0099620 | 99,620 | UDP-4-amino-4-deoxy-L-arabinose:2-oxoglutarate transaminase activity | molecular_function | Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinose + 2-oxoglutarate = UDP-beta-L-threo-pentopyranos-4-ulose + L-glutamate. | [
"PMID:12429098",
"PMID:12704196",
"RHEA:24710"
] | null | [
"UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase",
"UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase",
"UDP-4-amino-4-deoxy-L-arabinose aminotransferase",
"UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase",
"UDP-Ara4O aminotransferase",
"UDP-L-Ar... | [
"EXACT",
"EXACT",
"BROAD",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [
"EC:2.6.1.87",
"RHEA:24710"
] | [
"GO:0008483"
] | [] | [] | [] | [
"GO:0008483"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:2.6.1.87",
"skos:exactMatch RHEA:24710",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31140\" xsd:anyURI"
] | null | null | false | true | 3 |
GO:0099621 | 99,621 | undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity | molecular_function | Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate. | [
"GOC:al",
"GOC:dos",
"PMID:11706007",
"PMID:15695810"
] | null | [
"Ara4FN transferase activity",
"undecaprenyl phosphate-L-Ara4FN transferase activity",
"undecaprenyl-phosphate Ara4FN transferase activity"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [
"GO:0103019"
] | [] | [
"EC:2.4.2.53",
"MetaCyc:RXN0-3521",
"RHEA:27722"
] | [
"GO:0016763"
] | [] | [] | [] | [
"GO:0016763"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:2.4.2.53",
"skos:exactMatch RHEA:27722",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI"
] | null | null | false | true | 6 |
GO:0099622 | 99,622 | cardiac muscle cell membrane repolarization | biological_process | The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative res... | [
"GOC:BHF"
] | null | [] | [] | [] | [] | [] | [
"GO:0086009"
] | [] | [] | [] | [
"GO:0086009"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099623 | 99,623 | regulation of cardiac muscle cell membrane repolarization | biological_process | Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte. | [
"GOC:BHF",
"GOC:dos",
"GOC:rl"
] | null | [
"heart repolarization",
"regulation of cardiac muscle cell repolarization",
"regulation of cardiomyocyte membrane repolarization"
] | [
"RELATED",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0060306"
] | [
"regulates GO:0099622"
] | [
"regulates"
] | [
"GO:0099622"
] | [
"GO:0060306",
"GO:0099622"
] | [
"GO:0065007",
"regulates GO:0099622"
] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0099624 | 99,624 | atrial cardiac muscle cell membrane repolarization | biological_process | The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a nega... | [
"GOC:BHF"
] | null | [] | [] | [] | [] | [] | [
"GO:0099622"
] | [] | [] | [] | [
"GO:0099622"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099625 | 99,625 | ventricular cardiac muscle cell membrane repolarization | biological_process | The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a ... | [
"GOC:BHF",
"GOC:mtg_cardiac_conduct_nov11"
] | null | [] | [] | [] | [] | [] | [
"GO:0099622"
] | [] | [] | [] | [
"GO:0099622"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099626 | 99,626 | voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels | molecular_function | Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels. | [
"GOC:dos",
"PMID:15548655"
] | null | [
"voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099511"
] | [
"occurs_in GO:0098793",
"part_of GO:0099509"
] | [
"occurs_in",
"part_of"
] | [
"GO:0098793",
"GO:0099509"
] | [
"GO:0098793",
"GO:0099509",
"GO:0099511"
] | [
"GO:0005245",
"part_of GO:0099509"
] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099627 | 99,627 | neurotransmitter receptor cycle | biological_process | The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back t... | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0099637"
] | [] | [] | [] | [
"GO:0099637"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099628 | 99,628 | neurotransmitter receptor diffusion trapping | biological_process | The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane. | [
"PMID:18832033"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0098953"
] | [
"occurs_in GO:0098590"
] | [
"occurs_in"
] | [
"GO:0098590"
] | [
"GO:0098590",
"GO:0098953"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0099629 | 99,629 | postsynaptic specialization of symmetric synapse | cellular_component | A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electr... | [
"PMID:18832033"
] | null | [
"postsynaptic density of inhibitory synapse"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099572"
] | [
"part_of GO:0032280"
] | [
"part_of"
] | [
"GO:0032280"
] | [
"GO:0032280",
"GO:0099572"
] | [
"GO:0099572",
"part_of GO:0032280"
] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099630 | 99,630 | postsynaptic neurotransmitter receptor cycle | biological_process | The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome... | [
"PMID:18832033"
] | null | [] | [] | [] | [] | [] | [
"GO:0051649",
"GO:0099627"
] | [
"occurs_in GO:0098794"
] | [
"occurs_in"
] | [
"GO:0098794"
] | [
"GO:0051649",
"GO:0098794",
"GO:0099627"
] | [
"GO:0099627",
"occurs_in GO:0098794"
] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099631 | 99,631 | postsynaptic endocytic zone cytoplasmic component | cellular_component | The cytoplasmic component of the postsynaptic endocytic zone. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099738"
] | [
"part_of GO:0098843"
] | [
"part_of"
] | [
"GO:0098843"
] | [
"GO:0098843",
"GO:0099738"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099632 | 99,632 | protein transport within plasma membrane | biological_process | A process in which protein is transported from one region of the plasma membrane to another. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0032594"
] | [
"occurs_in GO:0005886"
] | [
"occurs_in"
] | [
"GO:0005886"
] | [
"GO:0005886",
"GO:0032594"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099633 | 99,633 | protein localization to postsynaptic specialization membrane | biological_process | A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density). | [
"GOC:dos"
] | null | [
"protein localisation in postsynaptic specialization membrane"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0033365",
"GO:1903539"
] | [] | [] | [] | [
"GO:0033365",
"GO:1903539"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 8 |
GO:0099634 | 99,634 | postsynaptic specialization membrane | cellular_component | The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0097060"
] | [
"part_of GO:0045211",
"part_of GO:0099572"
] | [
"part_of",
"part_of"
] | [
"GO:0045211",
"GO:0099572"
] | [
"GO:0045211",
"GO:0097060",
"GO:0099572"
] | [
"GO:0016020",
"part_of GO:0045211",
"part_of GO:0099572"
] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099635 | 99,635 | voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels | molecular_function | Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [
"Reactome:R-HSA-9659515 \"CACNA1D:CACNA2D2:CACNB2 (Cav1.3 channel) transports Ca2+ into the cytosol of an inner hair cell\""
] | [
"GO:0005245"
] | [
"occurs_in GO:0098793",
"part_of GO:0099703"
] | [
"occurs_in",
"part_of"
] | [
"GO:0098793",
"GO:0099703"
] | [
"GO:0005245",
"GO:0098793",
"GO:0099703"
] | [
"GO:0005245",
"part_of GO:0099533"
] | [] | [] | [] | [] | [] | null | null | false | true | 9 |
GO:0099636 | 99,636 | cytoplasmic streaming | biological_process | The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains. | [
"GOC:dos",
"Wikipedia:Cytoplasmic_streaming&oldid=706214009"
] | null | [] | [] | [] | [] | [
"Wikipedia:Cytoplasmic_streaming"
] | [
"GO:0046907"
] | [] | [] | [] | [
"GO:0046907"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 3 |
GO:0099637 | 99,637 | neurotransmitter receptor transport | biological_process | The directed movement of neurotransmitter receptors. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0015031",
"GO:0031503"
] | [] | [] | [] | [
"GO:0015031",
"GO:0031503"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099638 | 99,638 | endosome to plasma membrane protein transport | biological_process | The directed movement of proteins from the endosome to the plasma membrane in transport vesicles. | [
"GOC:dos"
] | null | [] | [] | [] | [] | [] | [
"GO:0006886",
"GO:0032456",
"GO:0061951",
"GO:0072659"
] | [] | [] | [] | [
"GO:0006886",
"GO:0032456",
"GO:0061951",
"GO:0072659"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099639 | 99,639 | neurotransmitter receptor transport, endosome to plasma membrane | biological_process | The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0098877",
"GO:0099638"
] | [] | [] | [] | [
"GO:0098877",
"GO:0099638"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099640 | 99,640 | axo-dendritic protein transport | biological_process | The directed movement of proteins along microtubules in neuron projections. | [
"ISBN:0815316194"
] | null | [
"axonal protein transport"
] | [
"NARROW"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0008088",
"GO:0098840"
] | [] | [] | [] | [
"GO:0008088",
"GO:0098840"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099641 | 99,641 | anterograde axonal protein transport | biological_process | The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons. | [
"GOC:dos"
] | null | [
"anterograde axon cargo transport"
] | [
"BROAD"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0008089",
"GO:0099640",
"GO:1905383"
] | [] | [] | [] | [
"GO:0008089",
"GO:0099640",
"GO:1905383"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 6 |
GO:0099642 | 99,642 | retrograde axonal protein transport | biological_process | The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons. | [
"ISBN:0815316194"
] | null | [
"retrograde axon cargo transport"
] | [
"BROAD"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0008090",
"GO:0099640"
] | [] | [] | [] | [
"GO:0008090",
"GO:0099640"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 2 |
GO:0099643 | 99,643 | signal release from synapse | biological_process | Any signal release from a synapse. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0023061"
] | [
"occurs_in GO:0045202",
"part_of GO:0099536"
] | [
"occurs_in",
"part_of"
] | [
"GO:0045202",
"GO:0099536"
] | [
"GO:0023061",
"GO:0045202",
"GO:0099536"
] | [
"GO:0023061",
"occurs_in GO:0045202"
] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0099644 | 99,644 | protein localization to presynaptic membrane | biological_process | A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane. | [
"GOC:dos"
] | null | [
"protein localisation in presynaptic membrane",
"protein localisation to presynaptic membrane",
"protein localization in presynaptic membrane"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0072657",
"GO:1905383",
"GO:1990778"
] | [] | [] | [] | [
"GO:0072657",
"GO:1905383",
"GO:1990778"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 5 |
GO:0099645 | 99,645 | neurotransmitter receptor localization to postsynaptic specialization membrane | biological_process | A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density). | [
"GOC:dos"
] | null | [
"neurotransmitter receptor localisation in postsynaptic specialization membrane"
] | [
"EXACT"
] | [] | [
"goslim_synapse"
] | [] | [
"GO:0031503",
"GO:0097120",
"GO:0099072",
"GO:0099633"
] | [] | [] | [] | [
"GO:0031503",
"GO:0097120",
"GO:0099072",
"GO:0099633"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 4 |
GO:0099646 | 99,646 | neurotransmitter receptor transport, plasma membrane to endosome | biological_process | Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome. | [
"GOC:dos"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0036010",
"GO:0048227",
"GO:0072594",
"GO:0099637"
] | [] | [] | [] | [
"GO:0036010",
"GO:0048227",
"GO:0072594",
"GO:0099637"
] | [] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099699 | 99,699 | obsolete integral component of synaptic membrane | cellular_component | OBSOLETE. The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | [
"GOC:dos"
] | This term was obsoleted because it represents protein topology, not a cellular component. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0097060"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI"
] | dos | 2017-05-25T17:22:18Z | true | true | 3 |
GO:0099703 | 99,703 | induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration | biological_process | The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission. | [
"GOC:dos",
"ISBN:9780071120005"
] | null | [] | [] | [] | [
"goslim_synapse"
] | [] | [
"GO:0099171",
"GO:0099533",
"GO:2000302"
] | [
"part_of GO:0007268"
] | [
"part_of"
] | [
"GO:0007268"
] | [
"GO:0007268",
"GO:0099171",
"GO:0099533",
"GO:2000302"
] | [
"GO:0099533",
"positively_regulates GO:0016079"
] | [] | [] | [] | [] | [] | null | null | false | true | 1 |
GO:0099738 | 99,738 | cell cortex region | cellular_component | The complete extent of cell cortex that underlies some some region of the plasma membrane. | [
"GOC:dos"
] | null | [
"perimembrane region"
] | [
"EXACT"
] | [] | [
"gocheck_do_not_annotate"
] | [] | [
"GO:0005938",
"GO:0099568"
] | [] | [] | [] | [
"GO:0005938",
"GO:0099568"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31276\" xsd:anyURI"
] | null | null | false | true | 8 |
GO:0100001 | 100,001 | regulation of skeletal muscle contraction by action potential | biological_process | Any action potential process that regulates skeletal muscle contraction. | [
"GOC:cjm",
"GOC:obol"
] | null | [] | [] | [] | [] | [] | [
"GO:0001508",
"GO:0014819"
] | [] | [] | [] | [
"GO:0001508",
"GO:0014819"
] | [
"GO:0001508",
"regulates GO:0003009"
] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | false | true | 4 |
GO:0100002 | 100,002 | obsolete negative regulation of protein kinase activity by protein phosphorylation | biological_process | OBSOLETE. Any protein phosphorylation process that negatively regulates protein kinase activity. | [
"GOC:cjm",
"GOC:obol"
] | This term was obsoleted because it represents a molecular function. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0004860"
] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12351\" xsd:anyURI"
] | cjm | 2015-04-02T04:13:19Z | true | true | 2 |
GO:0100003 | 100,003 | obsolete positive regulation of sodium ion transport by transcription from RNA polymerase II promoter | biological_process | OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sodium ion transport. | [
"GOC:cjm",
"GOC:obol"
] | This term was obsoleted because it represents a GO-CAM model. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | true | true | 6 |
GO:0100005 | 100,005 | obsolete positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter | biological_process | OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates ethanol catabolic process. | [
"GOC:cjm",
"GOC:obol"
] | This term was obsoleted because it represents a GO-CAM model. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12739\" xsd:anyURI"
] | cjm | 2015-04-02T04:13:19Z | true | true | 4 |
GO:0100006 | 100,006 | obsolete positive regulation of sulfite transport by transcription from RNA polymerase II promoter | biological_process | OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfite transport. | [
"GOC:cjm",
"GOC:obol"
] | This term was obsoleted because it represents a GO-CAM model. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | true | true | 1 |
GO:0100007 | 100,007 | obsolete negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter | biological_process | OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates ceramide biosynthetic process. | [
"GOC:cjm",
"GOC:obol"
] | This term was obsoleted because it represents a GO-CAM model. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | true | true | 9 |
GO:0100008 | 100,008 | regulation of fever generation by prostaglandin biosynthetic process | biological_process | Any prostaglandin biosynthetic process process that regulates fever generation. | [
"GOC:cjm",
"GOC:obol"
] | null | [] | [] | [] | [] | [] | [
"GO:0001516"
] | [
"regulates GO:0001660"
] | [
"regulates"
] | [
"GO:0001660"
] | [
"GO:0001516",
"GO:0001660"
] | [
"GO:0001516",
"regulates GO:0001660"
] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | false | true | 3 |
GO:0100009 | 100,009 | regulation of fever generation by prostaglandin secretion | biological_process | Any prostaglandin secretion process that regulates fever generation. | [
"GOC:cjm",
"GOC:obol"
] | null | [] | [] | [] | [] | [] | [
"GO:0032310"
] | [
"regulates GO:0001660"
] | [
"regulates"
] | [
"GO:0001660"
] | [
"GO:0001660",
"GO:0032310"
] | [
"GO:0032310",
"regulates GO:0001660"
] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | false | true | 6 |
GO:0100010 | 100,010 | positive regulation of fever generation by prostaglandin biosynthetic process | biological_process | Any prostaglandin biosynthetic process process that positively_regulates fever generation. | [
"GOC:cjm",
"GOC:obol"
] | null | [] | [] | [] | [] | [] | [
"GO:0100008"
] | [
"positively_regulates GO:0001660"
] | [
"positively_regulates"
] | [
"GO:0001660"
] | [
"GO:0001660",
"GO:0100008"
] | [
"GO:0001516",
"positively_regulates GO:0001660"
] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | false | true | 9 |
GO:0100011 | 100,011 | positive regulation of fever generation by prostaglandin secretion | biological_process | Any prostaglandin secretion process that positively_regulates fever generation. | [
"GOC:cjm",
"GOC:obol"
] | null | [] | [] | [] | [] | [] | [
"GO:0100009"
] | [
"positively_regulates GO:0001660"
] | [
"positively_regulates"
] | [
"GO:0001660"
] | [
"GO:0001660",
"GO:0100009"
] | [
"GO:0032310",
"positively_regulates GO:0001660"
] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | false | true | 5 |
GO:0100012 | 100,012 | obsolete regulation of heart induction by canonical Wnt signaling pathway | biological_process | OBSOLETE. Any canonical Wnt signaling pathway process that regulates heart induction. | [
"GOC:cjm",
"GOC:obol"
] | This term was obsoleted because it represents a GO-CAM model. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0060070",
"GO:0090381"
] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25766\" xsd:anyURI"
] | cjm | 2015-04-02T04:13:19Z | true | true | 6 |
GO:0100013 | 100,013 | obsolete positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter | biological_process | OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates fatty acid beta-oxidation. | [
"GOC:cjm",
"GOC:obol"
] | This term was obsoleted because it represents a GO-CAM model. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | cjm | 2015-04-02T04:13:19Z | true | true | 4 |
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