go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0099548
99,548
trans-synaptic signaling by nitric oxide
biological_process
Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099163", "GO:0099543" ]
[]
[]
[]
[ "GO:0099163", "GO:0099543" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099549
99,549
trans-synaptic signaling by carbon monoxide
biological_process
Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099543" ]
[]
[]
[]
[ "GO:0099543" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099550
99,550
trans-synaptic signaling, modulating synaptic transmission
biological_process
Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0050804", "GO:0099537" ]
[]
[]
[]
[ "GO:0050804", "GO:0099537" ]
[ "GO:0099537", "regulates GO:0007268" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099551
99,551
trans-synaptic signaling by neuropeptide, modulating synaptic transmission
biological_process
Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099540", "GO:0099550" ]
[]
[]
[]
[ "GO:0099540", "GO:0099550" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0099552
99,552
trans-synaptic signaling by lipid, modulating synaptic transmission
biological_process
Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse.
[ "GOC:dos", "PMID:21531987" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099541", "GO:0099550" ]
[]
[]
[]
[ "GO:0099541", "GO:0099550" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0099553
99,553
trans-synaptic signaling by endocannabinoid, modulating synaptic transmission
biological_process
Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.
[ "GOC:dos", "PMID:21531987" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099542", "GO:0099552" ]
[]
[]
[]
[ "GO:0099542", "GO:0099552" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099554
99,554
trans-synaptic signaling by soluble gas, modulating synaptic transmission
biological_process
Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099543", "GO:0099550" ]
[]
[]
[]
[ "GO:0099543", "GO:0099550" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0099555
99,555
trans-synaptic signaling by nitric oxide, modulating synaptic transmission
biological_process
Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099548", "GO:0099554" ]
[]
[]
[]
[ "GO:0099548", "GO:0099554" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099556
99,556
trans-synaptic signaling by carbon monoxide, modulating synaptic transmission
biological_process
Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099549", "GO:0099554" ]
[]
[]
[]
[ "GO:0099549", "GO:0099554" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0099557
99,557
trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
biological_process
Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.
[ "GOC:dos", "PMID:19029886" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099545", "GO:0099550" ]
[]
[]
[]
[ "GO:0099545", "GO:0099550" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099558
99,558
maintenance of synapse structure
biological_process
A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds.
[ "GOC:dos", "PMID:24449494", "PMID:25611509" ]
null
[ "synaptic maintenance" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0034331", "GO:0050808" ]
[]
[]
[]
[ "GO:0034331", "GO:0050808" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099559
99,559
maintenance of alignment of postsynaptic density and presynaptic active zone
biological_process
The process by which alignment between postsynaptic density and presynaptic active zone is maintained.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099558" ]
[]
[]
[]
[ "GO:0099558" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099560
99,560
synaptic membrane adhesion
biological_process
The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
[ "GOC:dos" ]
null
[ "synapse adhesion between pre- and post-synapse" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098609" ]
[ "part_of GO:0050808" ]
[ "part_of" ]
[ "GO:0050808" ]
[ "GO:0050808", "GO:0098609" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099561
99,561
synaptic membrane adhesion to extracellular matrix
biological_process
The binding of a synaptic membrane to the extracellular matrix via adhesion molecules.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0007160" ]
[ "part_of GO:0050808" ]
[ "part_of" ]
[ "GO:0050808" ]
[ "GO:0007160", "GO:0050808" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0099562
99,562
maintenance of postsynaptic density structure
biological_process
A process which maintains the organization and the arrangement of proteins in the presynaptic density.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098880" ]
[]
[]
[]
[ "GO:0098880" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099563
99,563
modification of synaptic structure
biological_process
Any process that modifies the structure/morphology of a synapse.
[ "GOC:dos" ]
This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones.
[ "synapse remodelling" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0050808" ]
[]
[]
[]
[ "GO:0050808" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0099564
99,564
modification of synaptic structure, modulating synaptic transmission
biological_process
Any process that modulates synaptic transmission via modification of the structure of the synapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099563" ]
[ "regulates GO:0007268" ]
[ "regulates" ]
[ "GO:0007268" ]
[ "GO:0007268", "GO:0099563" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0099565
99,565
chemical synaptic transmission, postsynaptic
biological_process
The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.
[ "GOC:dos" ]
null
[ "postsynaptic process involved in chemical synaptic transmission" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0007166", "GO:0050877" ]
[ "occurs_in GO:0098794", "part_of GO:0007268" ]
[ "occurs_in", "part_of" ]
[ "GO:0098794", "GO:0007268" ]
[ "GO:0007166", "GO:0007268", "GO:0050877", "GO:0098794" ]
[ "GO:0007166", "occurs_in GO:0098794", "part_of GO:0007268" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099566
99,566
regulation of postsynaptic cytosolic calcium ion concentration
biological_process
Any process that regulates the concentration of calcium in the postsynaptic cytosol.
[ "GOC:dos" ]
null
[ "regulation of postsynaptic cytosolic calcium levels" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0051480" ]
[ "occurs_in GO:0098794" ]
[ "occurs_in" ]
[ "GO:0098794" ]
[ "GO:0051480", "GO:0098794" ]
[ "GO:0051480", "occurs_in GO:0098794" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099567
99,567
calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration
molecular_function
The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations.
[ "PMID:24442513", "PMID:26190970" ]
null
[ "calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels", "postsynaptic calcium ion buffering", "regulation of postsynaptic cytosolic calcium ion concentration by calcium ion buffering" ]
[ "EXACT", "EXACT", "RELATED" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0005509" ]
[ "occurs_in GO:0099524", "part_of GO:0099566" ]
[ "occurs_in", "part_of" ]
[ "GO:0099524", "GO:0099566" ]
[ "GO:0005509", "GO:0099524", "GO:0099566" ]
[ "GO:0005509", "part_of GO:0099566" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099568
99,568
cytoplasmic region
cellular_component
Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.
[ "GOC:dos" ]
null
[]
[]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0005737" ]
[]
[]
[]
[ "GO:0005737" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31276\" xsd:anyURI" ]
null
null
false
true
2
GO:0099569
99,569
presynaptic cytoskeleton
cellular_component
The portion of the cytoskeleton contained within the presynapse.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0005856" ]
[ "part_of GO:0098793" ]
[ "part_of" ]
[ "GO:0098793" ]
[ "GO:0005856", "GO:0098793" ]
[ "GO:0005856", "part_of GO:0098793" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0099571
99,571
postsynaptic cytoskeleton
cellular_component
The portion of the cytoskeleton contained within the postsynapse.
[ "GOC:dos", "PMID:19889835" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0005856" ]
[ "part_of GO:0098794" ]
[ "part_of" ]
[ "GO:0098794" ]
[ "GO:0005856", "GO:0098794" ]
[ "GO:0005856", "part_of GO:0098794" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099572
99,572
postsynaptic specialization
cellular_component
A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
[ "PMID:22046028" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0043226" ]
[ "part_of GO:0098794" ]
[ "part_of" ]
[ "GO:0098794" ]
[ "GO:0043226", "GO:0098794" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099573
99,573
glutamatergic postsynaptic density
cellular_component
The post-synaptic specialization of a glutamatergic excitatory synapse.
[ "GOC:dos" ]
null
[ "postsynaptic specialization, glutamatergic neuron-to-neuron synapse" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0014069" ]
[]
[]
[]
[ "GO:0014069" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099574
99,574
regulation of protein catabolic process at synapse, modulating synaptic transmission
biological_process
Any process that modulates synaptic transmission by regulating protein degradation at the synapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0050804", "GO:0140250" ]
[]
[]
[]
[ "GO:0050804", "GO:0140250" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099575
99,575
regulation of protein catabolic process at presynapse, modulating synaptic transmission
biological_process
Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0042176", "GO:0099171" ]
[]
[]
[]
[ "GO:0042176", "GO:0099171" ]
[ "GO:0042176", "occurs_in GO:0098793", "regulates GO:0007268" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099577
99,577
regulation of translation at presynapse, modulating synaptic transmission
biological_process
Any process that modulates synaptic transmission by regulating translation occurring at the presynapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099171", "GO:0099547", "GO:0140244" ]
[]
[]
[]
[ "GO:0099171", "GO:0099547", "GO:0140244" ]
[ "GO:0065007", "occurs_in GO:0098793", "regulates GO:0006412", "regulates GO:0007268" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099578
99,578
regulation of translation at postsynapse, modulating synaptic transmission
biological_process
Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse.
[ "GOC:dos" ]
Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099170", "GO:0099547", "GO:0140245" ]
[]
[]
[]
[ "GO:0099170", "GO:0099547", "GO:0140245" ]
[ "GO:0065007", "occurs_in GO:0098794", "regulates GO:0006412", "regulates GO:0007268" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099579
99,579
obsolete G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
molecular_function
OBSOLETE. A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential.
[ "GOC:dos" ]
The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
[ "G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0099528" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31205\" xsd:anyURI" ]
null
null
true
true
8
GO:0099580
99,580
obsolete monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential
molecular_function
OBSOLETE. Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.
[ "GOC:dos" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "ion antiporter activity involved in regulation of post-synaptic membrane potential", "ion antiporter activity involved in regulation of postsynaptic membrane potential" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24479\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
2
GO:0099581
99,581
obsolete ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential
molecular_function
OBSOLETE. Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.
[ "GOC:dos" ]
The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
[ "ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential", "ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0042625" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31205\" xsd:anyURI" ]
null
null
true
true
2
GO:0099582
99,582
obsolete neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration
molecular_function
OBSOLETE. Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol.
[ "GOC:dos" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0030594", "GO:0099509" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
null
null
true
true
2
GO:0099583
99,583
obsolete neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
molecular_function
OBSOLETE. Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol.
[ "GOC:dos" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[ "neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
null
null
true
true
3
GO:0099585
99,585
release of sequestered calcium ion into presynaptic cytosol
biological_process
The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0051209", "GO:0051649" ]
[ "occurs_in GO:0098793" ]
[ "occurs_in" ]
[ "GO:0098793" ]
[ "GO:0051209", "GO:0051649", "GO:0098793" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099586
99,586
release of sequestered calcium ion into postsynaptic cytosol
biological_process
The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0051209", "GO:0051649" ]
[ "occurs_in GO:0098794" ]
[ "occurs_in" ]
[ "GO:0098794" ]
[ "GO:0051209", "GO:0051649", "GO:0098794" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0099587
99,587
inorganic ion import across plasma membrane
biological_process
The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol.
[ "GOC:dos" ]
null
[ "inorganic ion import into cell" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0098739" ]
[]
[]
[]
[ "GO:0098739" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099588
99,588
positive regulation of postsynaptic cytosolic calcium concentration
biological_process
Any process that increases the concentration of calcium ions in the postsynaptic cytosol.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0007204" ]
[ "occurs_in GO:0098794" ]
[ "occurs_in" ]
[ "GO:0098794" ]
[ "GO:0007204", "GO:0098794" ]
[ "GO:0007204", "occurs_in GO:0098794" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0099589
99,589
serotonin receptor activity
molecular_function
Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0004888" ]
[]
[]
[]
[ "GO:0004888" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099590
99,590
neurotransmitter receptor internalization
biological_process
A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0031623" ]
[]
[]
[]
[ "GO:0031623" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099592
99,592
endocytosed synaptic vesicle processing via endosome
biological_process
The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.
[ "GOC:dos" ]
null
[ "synaptic vesicle processing via endosome involved in synaptic vesicle recycling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0099003", "GO:0099532" ]
[ "part_of GO:0036466" ]
[ "part_of" ]
[ "GO:0036466" ]
[ "GO:0036466", "GO:0099003", "GO:0099532" ]
[ "GO:0099532", "part_of GO:0036466" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099593
99,593
endocytosed synaptic vesicle to endosome fusion
biological_process
Fusion of an endocytosed synaptic vesicle with an endosome.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0016189" ]
[ "part_of GO:0036466" ]
[ "part_of" ]
[ "GO:0036466" ]
[ "GO:0016189", "GO:0036466" ]
[ "GO:0016189", "part_of GO:0036466" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099601
99,601
regulation of neurotransmitter receptor activity
biological_process
Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors.
[ "GOC:dos" ]
null
[]
[]
[]
[ "gocheck_obsoletion_candidate", "goslim_synapse" ]
[]
[ "GO:0010469" ]
[ "regulates GO:0030594" ]
[ "regulates" ]
[ "GO:0030594" ]
[ "GO:0010469", "GO:0030594" ]
[ "GO:0065007", "regulates GO:0030594" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099602
99,602
neurotransmitter receptor regulator activity
molecular_function
A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.
[ "GOC:dos", "PMID:12740117", "PMID:18387948" ]
null
[]
[]
[]
[]
[]
[ "GO:0030545" ]
[ "regulates GO:0030594" ]
[ "regulates" ]
[ "GO:0030594" ]
[ "GO:0030545", "GO:0030594" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099604
99,604
ligand-gated calcium channel activity
molecular_function
Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-1168376 \"STIM1 oligomerizes\"", "Reactome:R-HSA-169680 \"IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel\"", "Reactome:R-HSA-169683 \"IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol\"", "Reactome:R-HSA-4420052 \"Decreasing cGMP concentration pro...
[ "GO:0005262", "GO:0099094" ]
[ "part_of GO:0019722" ]
[ "part_of" ]
[ "GO:0019722" ]
[ "GO:0005262", "GO:0019722", "GO:0099094" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099605
99,605
regulation of action potential firing rate
biological_process
Any process that regulates the frequency of action potentials in a spike train.
[ "ISBN:978-0071390118" ]
null
[]
[]
[]
[]
[]
[ "GO:0098900" ]
[]
[]
[]
[ "GO:0098900" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099606
99,606
microtubule plus-end directed mitotic chromosome migration
biological_process
The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.
[ "GOC:dos", "PMID:26258632", "PMID:26705896" ]
null
[ "plus-end directed chromosome gliding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007018", "GO:0050000", "GO:0051649", "GO:0051656", "GO:1903047" ]
[ "part_of GO:0007080" ]
[ "part_of" ]
[ "GO:0007080" ]
[ "GO:0007018", "GO:0007080", "GO:0050000", "GO:0051649", "GO:0051656", "GO:1903047" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099607
99,607
lateral attachment of mitotic spindle microtubules to kinetochore
biological_process
The cellular process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).
[ "PMID:26258632", "PMID:26705896" ]
null
[]
[]
[]
[]
[]
[ "GO:0051315" ]
[]
[]
[]
[ "GO:0051315" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099608
99,608
regulation of action potential firing pattern
biological_process
Any process that regulates the temporal pattern of a sequence of action potentials in a neuron.
[ "ISBN:978-0071390118" ]
null
[ "spike train sculpting" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0098900" ]
[ "regulates GO:0098874" ]
[ "regulates" ]
[ "GO:0098874" ]
[ "GO:0098874", "GO:0098900" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099609
99,609
microtubule lateral binding
molecular_function
Binding to the side of a microtubule.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0008017" ]
[]
[]
[]
[ "GO:0008017" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0099610
99,610
action potential initiation
biological_process
The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.
[ "ISBN:978-0071390118", "PMID:19439602" ]
null
[ "action potential firing", "action potential triggering" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0001508" ]
[]
[]
[]
[ "GO:0001508" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099611
99,611
regulation of action potential firing threshold
biological_process
Any process that regulates the potential at which an axon potential is triggered.
[ "ISBN:978-0071390118" ]
null
[]
[]
[]
[]
[]
[ "GO:0098900" ]
[]
[]
[]
[ "GO:0098900" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099612
99,612
protein localization to axon
biological_process
A process in which a protein is transported to or maintained in a location within an axon.
[ "GOC:dos", "PMID:26157139" ]
null
[]
[]
[]
[]
[]
[ "GO:0008104" ]
[]
[]
[]
[ "GO:0008104" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099613
99,613
protein localization to cell wall
biological_process
The process of directing proteins towards the cell-wall.
[ "ISBN:0716731363" ]
null
[]
[]
[]
[]
[]
[ "GO:0008104", "GO:0071692" ]
[]
[]
[]
[ "GO:0008104", "GO:0071692" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099616
99,616
extrinsic component of matrix side of mitochondrial inner membrane
cellular_component
The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0031314" ]
[ "part_of GO:0099617" ]
[ "part_of" ]
[ "GO:0099617" ]
[ "GO:0031314", "GO:0099617" ]
[ "GO:0019898", "part_of GO:0099617" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099617
99,617
matrix side of mitochondrial inner membrane
cellular_component
The leaflet of a mitochondrial inner membrane that faces the matrix, including any protein embedded in, attached to, or peripherally associated with it.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0098576" ]
[ "part_of GO:0005743" ]
[ "part_of" ]
[ "GO:0005743" ]
[ "GO:0005743", "GO:0098576" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31515\" xsd:anyURI" ]
null
null
false
true
1
GO:0099618
99,618
UDP-glucuronate dehydrogenase activity
molecular_function
Catalysis of the reaction: UDP-alpha-D-glucuronate + NAD+ = UDP-beta-L-threo-pentopyranos-4-ulose + CO2 + NADH.
[ "RHEA:24702" ]
null
[ "UDP-GlcUA decarboxylase activity", "UDP-glucuronic acid dehydrogenase activity" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "EC:1.1.1.305", "MetaCyc:RXN0-1861", "RHEA:24702" ]
[ "GO:0016616" ]
[]
[]
[]
[ "GO:0016616" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.1.1.305", "skos:exactMatch MetaCyc:RXN0-1861", "skos:exactMatch RHEA:24702", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29382\" xsd:anyURI" ]
null
null
false
true
6
GO:0099619
99,619
UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity
molecular_function
Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
[ "PMID:15695810", "PMID:15807526", "PMID:15809294", "PMID:15939024", "PMID:17928292" ]
null
[ "10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity", "ArnAFT activity", "UDP-L-Ara4N formyltransferase activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "EC:2.1.2.13", "RHEA:24706" ]
[ "GO:0016742" ]
[]
[]
[]
[ "GO:0016742" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.1.2.13", "skos:exactMatch RHEA:24706", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
null
null
false
true
3
GO:0099620
99,620
UDP-4-amino-4-deoxy-L-arabinose:2-oxoglutarate transaminase activity
molecular_function
Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinose + 2-oxoglutarate = UDP-beta-L-threo-pentopyranos-4-ulose + L-glutamate.
[ "PMID:12429098", "PMID:12704196", "RHEA:24710" ]
null
[ "UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase", "UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase", "UDP-4-amino-4-deoxy-L-arabinose aminotransferase", "UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase", "UDP-Ara4O aminotransferase", "UDP-L-Ar...
[ "EXACT", "EXACT", "BROAD", "EXACT", "EXACT", "EXACT" ]
[]
[]
[ "EC:2.6.1.87", "RHEA:24710" ]
[ "GO:0008483" ]
[]
[]
[]
[ "GO:0008483" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.6.1.87", "skos:exactMatch RHEA:24710", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31140\" xsd:anyURI" ]
null
null
false
true
3
GO:0099621
99,621
undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity
molecular_function
Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate.
[ "GOC:al", "GOC:dos", "PMID:11706007", "PMID:15695810" ]
null
[ "Ara4FN transferase activity", "undecaprenyl phosphate-L-Ara4FN transferase activity", "undecaprenyl-phosphate Ara4FN transferase activity" ]
[ "EXACT", "EXACT", "EXACT" ]
[ "GO:0103019" ]
[]
[ "EC:2.4.2.53", "MetaCyc:RXN0-3521", "RHEA:27722" ]
[ "GO:0016763" ]
[]
[]
[]
[ "GO:0016763" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.2.53", "skos:exactMatch RHEA:27722", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
null
null
false
true
6
GO:0099622
99,622
cardiac muscle cell membrane repolarization
biological_process
The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative res...
[ "GOC:BHF" ]
null
[]
[]
[]
[]
[]
[ "GO:0086009" ]
[]
[]
[]
[ "GO:0086009" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099623
99,623
regulation of cardiac muscle cell membrane repolarization
biological_process
Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.
[ "GOC:BHF", "GOC:dos", "GOC:rl" ]
null
[ "heart repolarization", "regulation of cardiac muscle cell repolarization", "regulation of cardiomyocyte membrane repolarization" ]
[ "RELATED", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0060306" ]
[ "regulates GO:0099622" ]
[ "regulates" ]
[ "GO:0099622" ]
[ "GO:0060306", "GO:0099622" ]
[ "GO:0065007", "regulates GO:0099622" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0099624
99,624
atrial cardiac muscle cell membrane repolarization
biological_process
The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a nega...
[ "GOC:BHF" ]
null
[]
[]
[]
[]
[]
[ "GO:0099622" ]
[]
[]
[]
[ "GO:0099622" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099625
99,625
ventricular cardiac muscle cell membrane repolarization
biological_process
The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a ...
[ "GOC:BHF", "GOC:mtg_cardiac_conduct_nov11" ]
null
[]
[]
[]
[]
[]
[ "GO:0099622" ]
[]
[]
[]
[ "GO:0099622" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099626
99,626
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
molecular_function
Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels.
[ "GOC:dos", "PMID:15548655" ]
null
[ "voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099511" ]
[ "occurs_in GO:0098793", "part_of GO:0099509" ]
[ "occurs_in", "part_of" ]
[ "GO:0098793", "GO:0099509" ]
[ "GO:0098793", "GO:0099509", "GO:0099511" ]
[ "GO:0005245", "part_of GO:0099509" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099627
99,627
neurotransmitter receptor cycle
biological_process
The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back t...
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0099637" ]
[]
[]
[]
[ "GO:0099637" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099628
99,628
neurotransmitter receptor diffusion trapping
biological_process
The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane.
[ "PMID:18832033" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098953" ]
[ "occurs_in GO:0098590" ]
[ "occurs_in" ]
[ "GO:0098590" ]
[ "GO:0098590", "GO:0098953" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0099629
99,629
postsynaptic specialization of symmetric synapse
cellular_component
A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electr...
[ "PMID:18832033" ]
null
[ "postsynaptic density of inhibitory synapse" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099572" ]
[ "part_of GO:0032280" ]
[ "part_of" ]
[ "GO:0032280" ]
[ "GO:0032280", "GO:0099572" ]
[ "GO:0099572", "part_of GO:0032280" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099630
99,630
postsynaptic neurotransmitter receptor cycle
biological_process
The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome...
[ "PMID:18832033" ]
null
[]
[]
[]
[]
[]
[ "GO:0051649", "GO:0099627" ]
[ "occurs_in GO:0098794" ]
[ "occurs_in" ]
[ "GO:0098794" ]
[ "GO:0051649", "GO:0098794", "GO:0099627" ]
[ "GO:0099627", "occurs_in GO:0098794" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099631
99,631
postsynaptic endocytic zone cytoplasmic component
cellular_component
The cytoplasmic component of the postsynaptic endocytic zone.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099738" ]
[ "part_of GO:0098843" ]
[ "part_of" ]
[ "GO:0098843" ]
[ "GO:0098843", "GO:0099738" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099632
99,632
protein transport within plasma membrane
biological_process
A process in which protein is transported from one region of the plasma membrane to another.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0032594" ]
[ "occurs_in GO:0005886" ]
[ "occurs_in" ]
[ "GO:0005886" ]
[ "GO:0005886", "GO:0032594" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099633
99,633
protein localization to postsynaptic specialization membrane
biological_process
A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density).
[ "GOC:dos" ]
null
[ "protein localisation in postsynaptic specialization membrane" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0033365", "GO:1903539" ]
[]
[]
[]
[ "GO:0033365", "GO:1903539" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0099634
99,634
postsynaptic specialization membrane
cellular_component
The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0097060" ]
[ "part_of GO:0045211", "part_of GO:0099572" ]
[ "part_of", "part_of" ]
[ "GO:0045211", "GO:0099572" ]
[ "GO:0045211", "GO:0097060", "GO:0099572" ]
[ "GO:0016020", "part_of GO:0045211", "part_of GO:0099572" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099635
99,635
voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels
molecular_function
Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[ "Reactome:R-HSA-9659515 \"CACNA1D:CACNA2D2:CACNB2 (Cav1.3 channel) transports Ca2+ into the cytosol of an inner hair cell\"" ]
[ "GO:0005245" ]
[ "occurs_in GO:0098793", "part_of GO:0099703" ]
[ "occurs_in", "part_of" ]
[ "GO:0098793", "GO:0099703" ]
[ "GO:0005245", "GO:0098793", "GO:0099703" ]
[ "GO:0005245", "part_of GO:0099533" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0099636
99,636
cytoplasmic streaming
biological_process
The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.
[ "GOC:dos", "Wikipedia:Cytoplasmic_streaming&oldid=706214009" ]
null
[]
[]
[]
[]
[ "Wikipedia:Cytoplasmic_streaming" ]
[ "GO:0046907" ]
[]
[]
[]
[ "GO:0046907" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0099637
99,637
neurotransmitter receptor transport
biological_process
The directed movement of neurotransmitter receptors.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0015031", "GO:0031503" ]
[]
[]
[]
[ "GO:0015031", "GO:0031503" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099638
99,638
endosome to plasma membrane protein transport
biological_process
The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.
[ "GOC:dos" ]
null
[]
[]
[]
[]
[]
[ "GO:0006886", "GO:0032456", "GO:0061951", "GO:0072659" ]
[]
[]
[]
[ "GO:0006886", "GO:0032456", "GO:0061951", "GO:0072659" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099639
99,639
neurotransmitter receptor transport, endosome to plasma membrane
biological_process
The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0098877", "GO:0099638" ]
[]
[]
[]
[ "GO:0098877", "GO:0099638" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099640
99,640
axo-dendritic protein transport
biological_process
The directed movement of proteins along microtubules in neuron projections.
[ "ISBN:0815316194" ]
null
[ "axonal protein transport" ]
[ "NARROW" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0008088", "GO:0098840" ]
[]
[]
[]
[ "GO:0008088", "GO:0098840" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099641
99,641
anterograde axonal protein transport
biological_process
The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.
[ "GOC:dos" ]
null
[ "anterograde axon cargo transport" ]
[ "BROAD" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0008089", "GO:0099640", "GO:1905383" ]
[]
[]
[]
[ "GO:0008089", "GO:0099640", "GO:1905383" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0099642
99,642
retrograde axonal protein transport
biological_process
The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons.
[ "ISBN:0815316194" ]
null
[ "retrograde axon cargo transport" ]
[ "BROAD" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0008090", "GO:0099640" ]
[]
[]
[]
[ "GO:0008090", "GO:0099640" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0099643
99,643
signal release from synapse
biological_process
Any signal release from a synapse.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0023061" ]
[ "occurs_in GO:0045202", "part_of GO:0099536" ]
[ "occurs_in", "part_of" ]
[ "GO:0045202", "GO:0099536" ]
[ "GO:0023061", "GO:0045202", "GO:0099536" ]
[ "GO:0023061", "occurs_in GO:0045202" ]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0099644
99,644
protein localization to presynaptic membrane
biological_process
A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane.
[ "GOC:dos" ]
null
[ "protein localisation in presynaptic membrane", "protein localisation to presynaptic membrane", "protein localization in presynaptic membrane" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0072657", "GO:1905383", "GO:1990778" ]
[]
[]
[]
[ "GO:0072657", "GO:1905383", "GO:1990778" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0099645
99,645
neurotransmitter receptor localization to postsynaptic specialization membrane
biological_process
A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
[ "GOC:dos" ]
null
[ "neurotransmitter receptor localisation in postsynaptic specialization membrane" ]
[ "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0031503", "GO:0097120", "GO:0099072", "GO:0099633" ]
[]
[]
[]
[ "GO:0031503", "GO:0097120", "GO:0099072", "GO:0099633" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0099646
99,646
neurotransmitter receptor transport, plasma membrane to endosome
biological_process
Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome.
[ "GOC:dos" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0036010", "GO:0048227", "GO:0072594", "GO:0099637" ]
[]
[]
[]
[ "GO:0036010", "GO:0048227", "GO:0072594", "GO:0099637" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099699
99,699
obsolete integral component of synaptic membrane
cellular_component
OBSOLETE. The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
[ "GOC:dos" ]
This term was obsoleted because it represents protein topology, not a cellular component.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0097060" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23424\" xsd:anyURI" ]
dos
2017-05-25T17:22:18Z
true
true
3
GO:0099703
99,703
induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration
biological_process
The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission.
[ "GOC:dos", "ISBN:9780071120005" ]
null
[]
[]
[]
[ "goslim_synapse" ]
[]
[ "GO:0099171", "GO:0099533", "GO:2000302" ]
[ "part_of GO:0007268" ]
[ "part_of" ]
[ "GO:0007268" ]
[ "GO:0007268", "GO:0099171", "GO:0099533", "GO:2000302" ]
[ "GO:0099533", "positively_regulates GO:0016079" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0099738
99,738
cell cortex region
cellular_component
The complete extent of cell cortex that underlies some some region of the plasma membrane.
[ "GOC:dos" ]
null
[ "perimembrane region" ]
[ "EXACT" ]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0005938", "GO:0099568" ]
[]
[]
[]
[ "GO:0005938", "GO:0099568" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31276\" xsd:anyURI" ]
null
null
false
true
8
GO:0100001
100,001
regulation of skeletal muscle contraction by action potential
biological_process
Any action potential process that regulates skeletal muscle contraction.
[ "GOC:cjm", "GOC:obol" ]
null
[]
[]
[]
[]
[]
[ "GO:0001508", "GO:0014819" ]
[]
[]
[]
[ "GO:0001508", "GO:0014819" ]
[ "GO:0001508", "regulates GO:0003009" ]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
false
true
4
GO:0100002
100,002
obsolete negative regulation of protein kinase activity by protein phosphorylation
biological_process
OBSOLETE. Any protein phosphorylation process that negatively regulates protein kinase activity.
[ "GOC:cjm", "GOC:obol" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0004860" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12351\" xsd:anyURI" ]
cjm
2015-04-02T04:13:19Z
true
true
2
GO:0100003
100,003
obsolete positive regulation of sodium ion transport by transcription from RNA polymerase II promoter
biological_process
OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sodium ion transport.
[ "GOC:cjm", "GOC:obol" ]
This term was obsoleted because it represents a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
true
true
6
GO:0100005
100,005
obsolete positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter
biological_process
OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates ethanol catabolic process.
[ "GOC:cjm", "GOC:obol" ]
This term was obsoleted because it represents a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12739\" xsd:anyURI" ]
cjm
2015-04-02T04:13:19Z
true
true
4
GO:0100006
100,006
obsolete positive regulation of sulfite transport by transcription from RNA polymerase II promoter
biological_process
OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfite transport.
[ "GOC:cjm", "GOC:obol" ]
This term was obsoleted because it represents a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
true
true
1
GO:0100007
100,007
obsolete negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter
biological_process
OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates ceramide biosynthetic process.
[ "GOC:cjm", "GOC:obol" ]
This term was obsoleted because it represents a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
true
true
9
GO:0100008
100,008
regulation of fever generation by prostaglandin biosynthetic process
biological_process
Any prostaglandin biosynthetic process process that regulates fever generation.
[ "GOC:cjm", "GOC:obol" ]
null
[]
[]
[]
[]
[]
[ "GO:0001516" ]
[ "regulates GO:0001660" ]
[ "regulates" ]
[ "GO:0001660" ]
[ "GO:0001516", "GO:0001660" ]
[ "GO:0001516", "regulates GO:0001660" ]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
false
true
3
GO:0100009
100,009
regulation of fever generation by prostaglandin secretion
biological_process
Any prostaglandin secretion process that regulates fever generation.
[ "GOC:cjm", "GOC:obol" ]
null
[]
[]
[]
[]
[]
[ "GO:0032310" ]
[ "regulates GO:0001660" ]
[ "regulates" ]
[ "GO:0001660" ]
[ "GO:0001660", "GO:0032310" ]
[ "GO:0032310", "regulates GO:0001660" ]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
false
true
6
GO:0100010
100,010
positive regulation of fever generation by prostaglandin biosynthetic process
biological_process
Any prostaglandin biosynthetic process process that positively_regulates fever generation.
[ "GOC:cjm", "GOC:obol" ]
null
[]
[]
[]
[]
[]
[ "GO:0100008" ]
[ "positively_regulates GO:0001660" ]
[ "positively_regulates" ]
[ "GO:0001660" ]
[ "GO:0001660", "GO:0100008" ]
[ "GO:0001516", "positively_regulates GO:0001660" ]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
false
true
9
GO:0100011
100,011
positive regulation of fever generation by prostaglandin secretion
biological_process
Any prostaglandin secretion process that positively_regulates fever generation.
[ "GOC:cjm", "GOC:obol" ]
null
[]
[]
[]
[]
[]
[ "GO:0100009" ]
[ "positively_regulates GO:0001660" ]
[ "positively_regulates" ]
[ "GO:0001660" ]
[ "GO:0001660", "GO:0100009" ]
[ "GO:0032310", "positively_regulates GO:0001660" ]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
false
true
5
GO:0100012
100,012
obsolete regulation of heart induction by canonical Wnt signaling pathway
biological_process
OBSOLETE. Any canonical Wnt signaling pathway process that regulates heart induction.
[ "GOC:cjm", "GOC:obol" ]
This term was obsoleted because it represents a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0060070", "GO:0090381" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25766\" xsd:anyURI" ]
cjm
2015-04-02T04:13:19Z
true
true
6
GO:0100013
100,013
obsolete positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter
biological_process
OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates fatty acid beta-oxidation.
[ "GOC:cjm", "GOC:obol" ]
This term was obsoleted because it represents a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
cjm
2015-04-02T04:13:19Z
true
true
4