Datasets:
LiteFold
/
GO

Dataset card Data Studio Files
xet
 Community
go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0106402
106,402
Lewis x epitope biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3)...
[ "PMID:16973732", "PMID:23000574" ]
null
[ "sialyl-Lewis X biosynthetic process", "sLeX biosynthetic process" ]
[ "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:1901137" ]
[]
[]
[]
[ "GO:1901137" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18144\" xsd:anyURI" ]
hjd
2021-10-12T20:20:55Z
false
true
1
GO:0106405
106,405
isoprenoid diphosphate phosphatase activity
molecular_function
Catalysis of the dephosphorylation of isoprenoid diphosphates.
[ "PMID:33246356" ]
null
[]
[]
[]
[]
[]
[ "GO:0016462" ]
[]
[]
[]
[ "GO:0016462" ]
[]
[]
[]
[]
[]
[]
hjd
2021-10-13T20:29:36Z
false
true
6
GO:0106407
106,407
Glc2Man9GlcNAc2 oligosaccharide glucosidase activity
molecular_function
Catalysis of the reaction: Glc(2)Man(9)GlcNAc(2)-[protein] + H2O = GlcMan(9)GlcNAc(2)-[protein] + beta-D-glucopyranose.
[ "EC:3.2.1.207", "PMID:30389790" ]
Trims Glc alpha 1,3 Glc bond in Glc2Man9GlcNAc2 oligosaccharide in inmature glycoproteins.
[ "glucosidase II" ]
[ "BROAD" ]
[]
[]
[ "EC:3.2.1.207", "RHEA:55996", "RHEA:56000" ]
[ "GO:0090599" ]
[]
[]
[]
[ "GO:0090599" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.2.1.207", "skos:narrowMatch RHEA:55996", "skos:narrowMatch RHEA:56000", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28029\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28242\" xsd:anyURI", "term_tracker_item \"https...
hjd
2021-10-28T00:35:46Z
false
true
3
GO:0106409
106,409
cyclic-di-AMP phosphodiesterase activity
molecular_function
Catalysis of the reaction: 3',3'-c-di-AMP + H2O = 5'-O-phosphonoadenylyl-(3'-5')-adenosine + H+.
[ "PMID:21909268", "RHEA:54420" ]
null
[]
[]
[]
[]
[ "EC:3.1.4.59", "MetaCyc:RXN-19814", "RHEA:54420" ]
[ "GO:0016779" ]
[]
[]
[]
[ "GO:0016779" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.1.4.59", "skos:exactMatch RHEA:54420", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2021-10-29T14:57:11Z
false
true
4
GO:0106410
106,410
box C/D sno(s)RNA 5'-end processing
biological_process
Any process involved in forming the mature 5' end of a box C/D RNA molecule.
[ "PMID:34352089" ]
null
[]
[]
[]
[]
[]
[ "GO:0034963", "GO:0180031" ]
[]
[]
[]
[ "GO:0034963", "GO:0180031" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26930\" xsd:anyURI" ]
hjd
2021-11-02T14:11:42Z
false
true
3
GO:0106413
106,413
RNA dihydrouridine synthase activity
molecular_function
Catalysis of the reaction: RNA-uracil + NAD(P)+ = RNA-dihydrouridine + NAD(P)H + H+.
[ "PMID:12581659", "PMID:25073379" ]
null
[]
[]
[]
[]
[ "RHEA:69843", "RHEA:69847" ]
[ "GO:0016628" ]
[]
[]
[]
[ "GO:0016628" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch RHEA:69843", "skos:narrowMatch RHEA:69847", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27519\" xsd:anyURI" ]
hjd
2021-12-08T16:34:41Z
false
true
6
GO:0106414
106,414
mRNA dihydrouridine synthase activity
molecular_function
Catalysis of the reaction: mRNA-uracil + NAD(P)+ = mRNA-dihydrouridine + NAD(P)H+ + H+.
[ "PMID:34798057" ]
null
[]
[]
[]
[]
[ "RHEA:69851", "RHEA:69855" ]
[ "GO:0106413" ]
[]
[]
[]
[ "GO:0106413" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch RHEA:69851", "skos:narrowMatch RHEA:69855", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27519\" xsd:anyURI" ]
hjd
2021-12-08T16:36:19Z
false
true
7
GO:0106415
106,415
muramoyltetrapeptide carboxypeptidase activity
molecular_function
GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelyl-D-alanine + H2O = GlcNAc-MurNAc-L-alanyl-gamma-D-glutamyl-meso-diaminopimelate + D-alanine.
[ "PMID:10428950", "PMID:15361936" ]
null
[]
[]
[]
[]
[ "EC:3.4.17.13", "RHEA:48688" ]
[ "GO:0004180" ]
[]
[]
[]
[ "GO:0004180" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.4.17.13", "skos:exactMatch RHEA:48688", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2021-12-21T14:33:53Z
false
true
2
GO:0106417
106,417
dopaminechrome tautomerase activity
molecular_function
Catalysis of the reaction: dopaminechrome = 5,6-dihydroxyindole.
[ "PMID:34388859", "RHEA:70199" ]
null
[]
[]
[]
[]
[ "RHEA:70199" ]
[ "GO:0016863" ]
[]
[]
[]
[ "GO:0016863" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:70199", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2022-01-06T14:51:16Z
false
true
6
GO:0106419
106,419
NAD-dependent protein lipoamidase activity
molecular_function
Catalysis of the reaction: (R)-N6-lipoyl-L-lysyl-[protein] + H2O + NAD+ = 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
[ "PMID:25525879", "RHEA:63640" ]
null
[]
[]
[]
[]
[ "EC:2.3.1.313", "MetaCyc:RXN-22964", "RHEA:63640" ]
[ "GO:0016747" ]
[]
[]
[]
[ "GO:0016747" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.3.1.313", "skos:exactMatch RHEA:63640", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27533\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2022-02-24T17:53:27Z
false
true
9
GO:0106420
106,420
NAD-dependent protein biotinidase activity
molecular_function
Catalysis of the reaction: H2O + N6-biotinyl-L-lysyl-[protein] + NAD+ = 2''-O-biotinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
[ "PMID:25525879", "RHEA:70479" ]
null
[]
[]
[]
[]
[ "RHEA:70479" ]
[ "GO:0016747" ]
[]
[]
[]
[ "GO:0016747" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:70479" ]
hjd
2022-02-24T17:55:29Z
false
true
8
GO:0106421
106,421
L-glutamate:proton antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamate(out) + H+(in) = L-glutamate(in) + H+(out).
[ "PMID:29273736" ]
null
[]
[]
[]
[]
[]
[ "GO:0005313", "GO:0015078", "GO:0140848" ]
[]
[]
[]
[ "GO:0005313", "GO:0015078", "GO:0140848" ]
[]
[]
[]
[]
[]
[]
hjd
2022-04-01T20:09:58Z
false
true
9
GO:0106423
106,423
tubulin-tyrosine carboxypeptidase activity
molecular_function
Catalysis of the reaction: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine.
[ "PMID:29146869", "PMID:35482892", "RHEA:57444" ]
null
[ "tubulinyl-Tyr carboxypeptidase" ]
[ "EXACT" ]
[]
[]
[ "EC:3.4.17.17", "RHEA:57444" ]
[ "GO:0004181" ]
[]
[]
[]
[ "GO:0004181" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.4.17.17", "skos:exactMatch RHEA:57444", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23419\" xsd:anyURI" ]
hjd
2022-05-31T13:19:27Z
false
true
2
GO:0106425
106,425
3,4-dihydroxyphenylacetaldehyde synthase activity
molecular_function
Catalysis of the reaction: L-dopa + O2 + H2O + H+ = 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2.
[ "PMID:21283636", "RHEA:55524" ]
null
[ "DHPAA synthase" ]
[ "EXACT" ]
[]
[]
[ "EC:4.1.1.107", "RHEA:55524" ]
[ "GO:0016831" ]
[]
[]
[]
[ "GO:0016831" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:4.1.1.107", "skos:exactMatch RHEA:55524", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23528\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2022-06-22T13:25:19Z
false
true
1
GO:0106426
106,426
regulation of kainate selective glutamate receptor signaling pathway
biological_process
Any process that modulates the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.
[ "PMID:12597860" ]
null
[]
[]
[]
[]
[]
[ "GO:1900449" ]
[ "regulates GO:0098991" ]
[ "regulates" ]
[ "GO:0098991" ]
[ "GO:0098991", "GO:1900449" ]
[ "GO:0065007", "regulates GO:0098991" ]
[]
[]
[]
[]
[]
hjd
2022-07-06T18:26:41Z
false
true
6
GO:0106427
106,427
negative regulation of kainate selective glutamate receptor signaling pathway
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.
[ "PMID:12597860" ]
null
[]
[]
[]
[]
[]
[ "GO:0106426", "GO:1900450" ]
[ "negatively_regulates GO:0098991" ]
[ "negatively_regulates" ]
[ "GO:0098991" ]
[ "GO:0098991", "GO:0106426", "GO:1900450" ]
[ "GO:0065007", "negatively_regulates GO:0098991" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31276\" xsd:anyURI" ]
hjd
2022-07-06T18:32:46Z
false
true
9
GO:0106428
106,428
positive regulation of kainate selective glutamate receptor signaling pathway
biological_process
Any process that activates or increases the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.
[ "PMID:12597860" ]
null
[]
[]
[]
[]
[]
[ "GO:0106426", "GO:1900451" ]
[ "positively_regulates GO:0098991" ]
[ "positively_regulates" ]
[ "GO:0098991" ]
[ "GO:0098991", "GO:0106426", "GO:1900451" ]
[ "GO:0065007", "positively_regulates GO:0098991" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23558\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31276\" xsd:anyURI" ]
hjd
2022-07-06T18:36:50Z
false
true
2
GO:0106429
106,429
11-cis-retinol dehydrogenase (NAD+) activity
molecular_function
Catalysis of the reaction: 11-cis-retinol--[retinol-binding protein] + NAD+ = 11-cis-retinal--[retinol-binding protein] + NADH + H+.
[ "RHEA:55668" ]
null
[ "11-cis-retinol dehydrogenase activity" ]
[ "BROAD" ]
[]
[]
[ "EC:1.1.1.315", "RHEA:55668" ]
[ "GO:0004022" ]
[]
[]
[]
[ "GO:0004022" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.1.1.315", "skos:exactMatch RHEA:55668", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23669\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30275\" xsd:anyURI" ]
hjd
2022-07-15T17:58:20Z
false
true
7
GO:0106430
106,430
dihydroorotate dehydrogenase (quinone) activity
molecular_function
(S)-dihydroorotate + a quinone = orotate + a quinol.
[ "RHEA:30187" ]
null
[]
[]
[]
[]
[ "EC:1.3.5.2", "RHEA:28691", "RHEA:29195", "RHEA:30187" ]
[ "GO:0004152", "GO:0016635" ]
[]
[]
[]
[ "GO:0004152", "GO:0016635" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.3.5.2", "skos:exactMatch RHEA:30187", "skos:narrowMatch RHEA:28691", "skos:narrowMatch RHEA:29195", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23786\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI"...
hjd
2022-07-26T19:27:20Z
false
true
3
GO:0106432
106,432
queuosine nucleosidase activity
molecular_function
Catalysis of the reaction: queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate.
[ "PMID:35940128", "RHEA:75387" ]
null
[ "queuosine nucleoside glycosylase", "tRNA queuosine nucleoside glycosylase" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "RHEA:75387" ]
[ "GO:0008477" ]
[]
[]
[]
[ "GO:0008477" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:75387", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23846\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29892\" xsd:anyURI" ]
hjd
2022-08-17T17:39:10Z
false
true
1
GO:0106433
106,433
O6-methyl-dGTP hydrolase activity
molecular_function
Catalysis of the reaction O6-methyl-dGTP + H2O = O6-methyl-dGMP + diphosphate + H+.
[ "PMID:30304478", "RHEA:67600" ]
null
[]
[]
[]
[]
[ "RHEA:67600" ]
[ "GO:0016818" ]
[]
[]
[]
[ "GO:0016818" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:67600", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21497\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2022-09-16T18:24:35Z
false
true
7
GO:0106434
106,434
retinal isomerization
biological_process
The reactions involved in isomerization of all trans to all cis retnal.
[ "PMID:21447403" ]
This process term replaces 'retinal isomerase' because the Enzyme Commission has determined that the reaction is known to be catalyzed by a pathway involving multiple steps, catalyzed by EC:1.1.1.300, EC:2.3.1.135, EC:3.1.1.64, and EC:1.1.1.315.
[]
[]
[]
[]
[]
[ "GO:0042574" ]
[]
[]
[]
[ "GO:0042574" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23669\" xsd:anyURI" ]
hjd
2022-09-28T16:44:26Z
false
true
6
GO:0106435
106,435
carboxylesterase activity
molecular_function
Catalysis of the reaction: a carboxylic ester + H2O = a carboxylate + an alcohol + H+.
[ "RHEA:21164" ]
Note: This covers a broad range of specificity; also hydrolyzes vitamin A esters.
[ "ali-esterase activity", "alpha-carboxylesterase activity", "B-esterase activity", "cocaine esterase", "nonspecific carboxylesterase activity", "procaine esterase", "serine esterase activity", "triacetin esterase", "vitamin A esterase" ]
[ "RELATED", "NARROW", "NARROW", "NARROW", "RELATED", "NARROW", "NARROW", "NARROW", "NARROW" ]
[]
[]
[ "EC:3.1.1.1", "MetaCyc:CARBOXYLESTERASE-RXN", "Reactome:R-HSA-9619024 \"CES1 trimer hydrolyses ACEI pro-drugs to ACEIs\"", "Reactome:R-HSA-9727567 \"CES1 hydrolyses sacubitril to sacubitrilat\"", "Reactome:R-HSA-9749647 \"CES2 hydrolyzes ASA-\"", "RHEA:21164", "RHEA:31779", "RHEA:38555", "RHEA:50148...
[ "GO:0052689" ]
[]
[]
[]
[ "GO:0052689" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.1.1.1", "skos:exactMatch RHEA:21164", "skos:narrowMatch RHEA:31779", "skos:narrowMatch RHEA:38555", "skos:narrowMatch RHEA:50148", "skos:narrowMatch RHEA:59388", "skos:narrowMatch RHEA:63052", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21843\" xsd:any...
hjd
2022-10-03T21:37:41Z
false
true
3
GO:0106436
106,436
glutathione-dependent sulfide quinone oxidoreductase activity
molecular_function
Catalysis of the reaction: a quinone + glutathione + H+ + hydrogen sulfide = a quinol + S-sulfanylglutathione.
[ "RHEA:55156" ]
null
[ "eukaryotic sulfide quinone oxidoreductase" ]
[ "RELATED" ]
[]
[]
[ "EC:1.8.5.8", "RHEA:55156", "RHEA:62608" ]
[ "GO:0016672" ]
[]
[]
[]
[ "GO:0016672" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.8.5.8", "skos:exactMatch RHEA:55156", "skos:narrowMatch RHEA:62608", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23325\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2022-10-07T00:15:41Z
false
true
6
GO:0106437
106,437
protein-glutamic acid ligase activity, initiating
molecular_function
Catalytic reaction: ATP + L-glutamate + L-glutamyl-[protein] = ADP + H+ + L-gamma-glutamyl-L-glutamyl-[protein] + phosphate.
[ "PMID:32747782", "RHEA:60144" ]
null
[]
[]
[]
[]
[ "RHEA:60144", "RHEA:69192" ]
[ "GO:0070739" ]
[]
[]
[]
[ "GO:0070739" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:60144", "skos:narrowMatch RHEA:69192", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21309\" xsd:anyURI" ]
hjd
2022-10-21T21:11:47Z
false
true
1
GO:0106438
106,438
protein-glutamic acid ligase activity, elongating
molecular_function
Catalytic reaction :(L-glutamyl)n-L-gamma-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate = (L-glutamyl)n+1-L-gamma-glutamyl-L-glutamyl-[protein] + ADP + H+ + phosphate.
[ "PMID:32747782", "RHEA:60148" ]
null
[]
[]
[]
[]
[ "RHEA:60148", "RHEA:69208" ]
[ "GO:0070739" ]
[]
[]
[]
[ "GO:0070739" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:60148", "skos:narrowMatch RHEA:69208", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21309\" xsd:anyURI" ]
hjd
2022-10-21T21:15:15Z
false
true
7
GO:0106439
106,439
L-lysine:L-arginine antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out).
[ "PMID:10903140", "RHEA:70827" ]
L-arginine:L-lysine antiporter activity
[]
[]
[]
[]
[ "RHEA:70827" ]
[ "GO:0015189", "GO:0015297", "GO:0061459" ]
[]
[]
[]
[ "GO:0015189", "GO:0015297", "GO:0061459" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:70827", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24324\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2022-11-08T21:55:18Z
false
true
8
GO:0110001
110,001
toxin-antitoxin complex
cellular_component
A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon.
[ "GOC:bhm", "PMID:16109374", "PMID:25093388" ]
An example is YoeB (P69348) in Escherichia coli in PMID:16109374 (inferred by direct evidence).
[]
[]
[]
[]
[]
[ "GO:0017053" ]
[]
[]
[]
[ "GO:0017053" ]
[]
[]
[]
[]
[]
[]
kmv
null
false
true
8
GO:0110002
110,002
regulation of tRNA methylation
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation.
[ "GOC:vw", "PMID:23074192" ]
null
[]
[]
[]
[]
[]
[ "GO:2000235" ]
[ "regulates GO:0030488" ]
[ "regulates" ]
[ "GO:0030488" ]
[ "GO:0030488", "GO:2000235" ]
[ "GO:0065007", "regulates GO:0030488" ]
[]
[]
[]
[]
[]
kmv
null
false
true
5
GO:0110003
110,003
regulation of tRNA C5-cytosine methylation
biological_process
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation.
[ "GOC:vw", "PMID:23074192" ]
null
[]
[]
[]
[]
[]
[ "GO:0110002" ]
[ "regulates GO:0002946" ]
[ "regulates" ]
[ "GO:0002946" ]
[ "GO:0002946", "GO:0110002" ]
[ "GO:0065007", "regulates GO:0002946" ]
[]
[]
[]
[]
[]
kmv
null
false
true
6
GO:0110004
110,004
positive regulation of tRNA methylation
biological_process
Any process that activates or increases the frequency, rate or extent of tRNA methylation.
[ "GOC:vw", "PMID:23074192" ]
null
[]
[]
[]
[]
[]
[ "GO:0110002", "GO:2000237" ]
[ "positively_regulates GO:0030488" ]
[ "positively_regulates" ]
[ "GO:0030488" ]
[ "GO:0030488", "GO:0110002", "GO:2000237" ]
[ "GO:0065007", "positively_regulates GO:0030488" ]
[]
[]
[]
[]
[]
kmv
null
false
true
5
GO:0110005
110,005
positive regulation of tRNA C5-cytosine methylation
biological_process
Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation.
[ "GOC:vw", "PMID:23074192" ]
null
[]
[]
[]
[]
[]
[ "GO:0110003", "GO:0110004" ]
[ "positively_regulates GO:0002946" ]
[ "positively_regulates" ]
[ "GO:0002946" ]
[ "GO:0002946", "GO:0110003", "GO:0110004" ]
[ "GO:0065007", "positively_regulates GO:0002946" ]
[]
[]
[]
[]
[]
kmv
null
false
true
4
GO:0110009
110,009
formin-nucleated actin cable organization
biological_process
A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0061572" ]
[]
[]
[]
[ "GO:0061572" ]
[]
[]
[]
[]
[]
[]
kmv
null
false
true
4
GO:0110010
110,010
basolateral protein secretion
biological_process
The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base.
[ "GOC:ha", "PMID:27404358" ]
null
[]
[]
[]
[]
[]
[ "GO:0009306" ]
[]
[]
[]
[ "GO:0009306" ]
[]
[]
[]
[]
[]
[]
kmv
null
false
true
1
GO:0110011
110,011
regulation of basement membrane organization
biological_process
Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.
[ "GOC:ha", "PMID:27404358" ]
null
[]
[]
[]
[]
[]
[ "GO:1903053" ]
[ "regulates GO:0071711" ]
[ "regulates" ]
[ "GO:0071711" ]
[ "GO:0071711", "GO:1903053" ]
[ "GO:0065007", "regulates GO:0071711" ]
[]
[]
[]
[]
[]
kmv
null
false
true
9
GO:0110012
110,012
protein localization to P-body
biological_process
Any process in which a protein is transported to, or maintained at, a P-body.
[ "GOC:mah", "PMID:28031482" ]
null
[ "protein localisation to P-body", "protein localization to cytoplasmic mRNA processing body", "protein localization to P body" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0033365" ]
[]
[]
[]
[ "GO:0033365" ]
[]
[]
[]
[]
[]
[]
kmv
2017-05-03T14:04:51Z
false
true
5
GO:0110013
110,013
positive regulation of aggregation involved in sorocarp development
biological_process
Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins ...
[ "GOC:rjd", "PMID:28257811" ]
null
[]
[]
[]
[]
[]
[ "GO:0032109", "GO:0048522", "GO:0051094", "GO:0060176" ]
[ "positively_regulates GO:0031152" ]
[ "positively_regulates" ]
[ "GO:0031152" ]
[ "GO:0031152", "GO:0032109", "GO:0048522", "GO:0051094", "GO:0060176" ]
[ "GO:0065007", "positively_regulates GO:0031152" ]
[]
[]
[]
[]
[]
kmv
2017-05-10T12:52:46Z
false
true
5
GO:0110014
110,014
negative regulation of aggregation involved in sorocarp development
biological_process
Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins ...
[ "GOC:rjd", "PMID:28257811" ]
null
[]
[]
[]
[]
[]
[ "GO:0032108", "GO:0048523", "GO:0051093", "GO:0060176" ]
[ "negatively_regulates GO:0031152" ]
[ "negatively_regulates" ]
[ "GO:0031152" ]
[ "GO:0031152", "GO:0032108", "GO:0048523", "GO:0051093", "GO:0060176" ]
[ "GO:0065007", "negatively_regulates GO:0031152" ]
[]
[]
[]
[]
[]
kmv
2017-05-10T12:53:12Z
false
true
9
GO:0110016
110,016
B-WICH complex
cellular_component
A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during earl...
[ "GOC:bhm", "PMID:16603771", "PMID:21559432", "PMID:23555303", "PMID:26044184" ]
An example is BAZ1B (Q9UIG0) in human in PMID:16603771 (by IPI).
[]
[]
[]
[]
[]
[ "GO:0070603" ]
[ "part_of GO:0005730" ]
[ "part_of" ]
[ "GO:0005730" ]
[ "GO:0005730", "GO:0070603" ]
[]
[]
[]
[]
[]
[]
kmv
2017-05-26T19:53:53Z
false
true
3
GO:0110018
110,018
cap-independent translational initiation of circular RNA
biological_process
The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.
[ "GOC:sp", "PMID:28281539", "PMID:28344080", "PMID:28344082" ]
null
[ "cap-independent translational initiation of circRNA" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0002190" ]
[]
[]
[]
[ "GO:0002190" ]
[]
[]
[]
[]
[]
[]
kmv
2017-06-08T15:22:35Z
false
true
9
GO:0110019
110,019
IRES-dependent translational initiation of circular RNA
biological_process
The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.
[ "GOC:sp", "PMID:28281539", "PMID:28344080", "PMID:28344082" ]
null
[ "IRES-dependent translational initiation of circRNA" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0110018" ]
[ "has_part GO:0160297" ]
[ "has_part" ]
[ "GO:0160297" ]
[ "GO:0110018", "GO:0160297" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30674\" xsd:anyURI" ]
kmv
2017-06-08T15:36:38Z
false
true
9
GO:0110020
110,020
regulation of actomyosin structure organization
biological_process
Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.
[ "GOC:lf", "PMID:22790195" ]
null
[]
[]
[]
[]
[]
[ "GO:0032956" ]
[ "regulates GO:0031032" ]
[ "regulates" ]
[ "GO:0031032" ]
[ "GO:0031032", "GO:0032956" ]
[ "GO:0065007", "regulates GO:0031032" ]
[]
[]
[]
[]
[]
kmv
2017-06-20T19:28:58Z
false
true
3
GO:0110021
110,021
cardiac muscle myoblast proliferation
biological_process
The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:26512644" ]
null
[]
[]
[]
[]
[]
[ "GO:0051450" ]
[]
[]
[]
[ "GO:0051450" ]
[]
[]
[]
[]
[]
[]
kmv
2017-06-29T14:35:24Z
false
true
4
GO:0110022
110,022
regulation of cardiac muscle myoblast proliferation
biological_process
Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:26512644" ]
null
[]
[]
[]
[]
[]
[ "GO:2000291" ]
[ "regulates GO:0110021" ]
[ "regulates" ]
[ "GO:0110021" ]
[ "GO:0110021", "GO:2000291" ]
[ "GO:0065007", "regulates GO:0110021" ]
[]
[]
[]
[]
[]
kmv
2017-06-29T15:11:47Z
false
true
7
GO:0110023
110,023
negative regulation of cardiac muscle myoblast proliferation
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:26512644" ]
null
[]
[]
[]
[]
[]
[ "GO:0110022", "GO:2000818" ]
[ "negatively_regulates GO:0110021" ]
[ "negatively_regulates" ]
[ "GO:0110021" ]
[ "GO:0110021", "GO:0110022", "GO:2000818" ]
[ "GO:0065007", "negatively_regulates GO:0110021" ]
[]
[]
[]
[]
[]
kmv
2017-06-29T15:18:30Z
false
true
9
GO:0110024
110,024
positive regulation of cardiac muscle myoblast proliferation
biological_process
Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:26512644" ]
null
[]
[]
[]
[]
[]
[ "GO:0110022", "GO:2000288" ]
[ "positively_regulates GO:0110021" ]
[ "positively_regulates" ]
[ "GO:0110021" ]
[ "GO:0110021", "GO:0110022", "GO:2000288" ]
[ "GO:0065007", "positively_regulates GO:0110021" ]
[]
[]
[]
[]
[]
kmv
2017-06-29T15:24:16Z
false
true
6
GO:0110026
110,026
regulation of DNA strand resection involved in replication fork processing
biological_process
Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing.
[ "GOC:mah", "PMID:28475874" ]
null
[]
[]
[]
[]
[]
[ "GO:0051052" ]
[ "regulates GO:0110025" ]
[ "regulates" ]
[ "GO:0110025" ]
[ "GO:0051052", "GO:0110025" ]
[ "GO:0065007", "regulates GO:0110025" ]
[]
[]
[]
[]
[]
kmv
2017-07-05T18:21:06Z
false
true
6
GO:0110027
110,027
negative regulation of DNA strand resection involved in replication fork processing
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.
[ "GOC:mah", "PMID:28475874" ]
null
[]
[]
[]
[]
[]
[ "GO:0110026", "GO:2000104" ]
[ "negatively_regulates GO:0110025" ]
[ "negatively_regulates" ]
[ "GO:0110025" ]
[ "GO:0110025", "GO:0110026", "GO:2000104" ]
[ "GO:0065007", "negatively_regulates GO:0110025" ]
[]
[]
[]
[]
[]
kmv
2017-07-05T18:39:49Z
false
true
4
GO:0110028
110,028
positive regulation of mitotic spindle organization
biological_process
Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.
[ "GOC:bhm", "PMID:17576815" ]
null
[]
[]
[]
[]
[]
[ "GO:0045931", "GO:0051495", "GO:0060236", "GO:0090068" ]
[ "positively_regulates GO:0007052" ]
[ "positively_regulates" ]
[ "GO:0007052" ]
[ "GO:0007052", "GO:0045931", "GO:0051495", "GO:0060236", "GO:0090068" ]
[ "GO:0065007", "positively_regulates GO:0007052" ]
[]
[]
[]
[]
[]
kmv
2017-07-06T14:14:08Z
false
true
9
GO:0110029
110,029
negative regulation of meiosis I
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
[ "GOC:vw" ]
null
[]
[]
[]
[]
[]
[ "GO:0045835", "GO:0060631" ]
[ "negatively_regulates GO:0007127" ]
[ "negatively_regulates" ]
[ "GO:0007127" ]
[ "GO:0007127", "GO:0045835", "GO:0060631" ]
[ "GO:0065007", "negatively_regulates GO:0007127" ]
[]
[]
[]
[]
[]
kmv
2017-07-12T18:47:33Z
false
true
9
GO:0110030
110,030
regulation of G2/MI transition of meiotic cell cycle
biological_process
Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
[ "GOC:vw" ]
null
[]
[]
[]
[]
[]
[ "GO:1901993", "GO:1902749" ]
[ "regulates GO:0008315" ]
[ "regulates" ]
[ "GO:0008315" ]
[ "GO:0008315", "GO:1901993", "GO:1902749" ]
[ "GO:0065007", "regulates GO:0008315" ]
[]
[]
[]
[]
[]
kmv
2017-07-12T19:02:19Z
false
true
6
GO:0110031
110,031
negative regulation of G2/MI transition of meiotic cell cycle
biological_process
Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
[ "GOC:vw", "PMID:25492408" ]
null
[]
[]
[]
[]
[]
[ "GO:0110030", "GO:1901994", "GO:1902750" ]
[ "negatively_regulates GO:0008315" ]
[ "negatively_regulates" ]
[ "GO:0008315" ]
[ "GO:0008315", "GO:0110030", "GO:1901994", "GO:1902750" ]
[ "GO:0065007", "negatively_regulates GO:0008315" ]
[]
[]
[]
[]
[]
kmv
2017-07-12T20:36:35Z
false
true
8
GO:0110032
110,032
positive regulation of G2/MI transition of meiotic cell cycle
biological_process
Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
[ "GOC:vw", "PMID:25492408" ]
null
[]
[]
[]
[]
[]
[ "GO:0110030", "GO:1901995", "GO:1902751" ]
[ "positively_regulates GO:0008315" ]
[ "positively_regulates" ]
[ "GO:0008315" ]
[ "GO:0008315", "GO:0110030", "GO:1901995", "GO:1902751" ]
[ "GO:0065007", "positively_regulates GO:0008315" ]
[]
[]
[]
[]
[]
kmv
2017-07-12T20:40:54Z
false
true
1
GO:0110033
110,033
regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway
biological_process
Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenyl...
[ "GOC:al", "PMID:24297439" ]
null
[ "regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0106070", "GO:1902659" ]
[ "regulates GO:0010619" ]
[ "regulates" ]
[ "GO:0010619" ]
[ "GO:0010619", "GO:0106070", "GO:1902659" ]
[ "GO:0065007", "regulates GO:0010619" ]
[]
[]
[]
[]
[]
kmv
2017-07-17T20:22:20Z
false
true
1
GO:0110034
110,034
negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway.
[ "GOC:al", "PMID:24297439" ]
null
[ "negative regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0106072", "GO:0110033", "GO:1902660" ]
[ "negatively_regulates GO:0010619" ]
[ "negatively_regulates" ]
[ "GO:0010619" ]
[ "GO:0010619", "GO:0106072", "GO:0110033", "GO:1902660" ]
[ "GO:0065007", "negatively_regulates GO:0010619" ]
[]
[]
[]
[]
[]
kmv
2017-07-17T20:35:55Z
false
true
2
GO:0110035
110,035
obsolete rDNA spacer replication fork barrier binding, bending
molecular_function
OBSOLETE. The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
[ "GOC:al", "GOC:vw", "PMID:27035982" ]
This term was obsoleted because it is precomposed.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0008301", "GO:0043110" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31529\" xsd:anyURI" ]
kmv
2017-07-17T21:09:50Z
true
true
2
GO:0110036
110,036
C2 domain binding
molecular_function
Binding to the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes.
[ "GOC:sl", "PMID:24882364" ]
null
[]
[]
[]
[]
[]
[ "GO:0019904" ]
[]
[]
[]
[ "GO:0019904" ]
[]
[]
[]
[]
[]
[]
kmv
2017-07-20T20:45:56Z
false
true
2
GO:0110037
110,037
regulation of nematode male tail tip morphogenesis
biological_process
Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized.
[ "GOC:rz", "PMID:28068334" ]
null
[]
[]
[]
[]
[]
[ "GO:0022603" ]
[ "regulates GO:0045138" ]
[ "regulates" ]
[ "GO:0045138" ]
[ "GO:0022603", "GO:0045138" ]
[ "GO:0065007", "regulates GO:0045138" ]
[]
[]
[]
[]
[]
kmv
2017-07-24T20:21:34Z
false
true
2
GO:0110038
110,038
negative regulation of nematode male tail tip morphogenesis
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.
[ "GOC:rz", "PMID:28068334" ]
null
[]
[]
[]
[]
[]
[ "GO:0051093", "GO:0051241", "GO:0110037" ]
[ "negatively_regulates GO:0045138" ]
[ "negatively_regulates" ]
[ "GO:0045138" ]
[ "GO:0045138", "GO:0051093", "GO:0051241", "GO:0110037" ]
[ "GO:0065007", "negatively_regulates GO:0045138" ]
[]
[]
[]
[]
[]
kmv
2017-07-24T20:29:00Z
false
true
2
GO:0110039
110,039
positive regulation of nematode male tail tip morphogenesis
biological_process
Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis.
[ "GOC:rz", "PMID:28068334" ]
null
[]
[]
[]
[]
[]
[ "GO:0051094", "GO:0051240", "GO:0110037" ]
[ "positively_regulates GO:0045138" ]
[ "positively_regulates" ]
[ "GO:0045138" ]
[ "GO:0045138", "GO:0051094", "GO:0051240", "GO:0110037" ]
[ "GO:0065007", "positively_regulates GO:0045138" ]
[]
[]
[]
[]
[]
kmv
2017-07-24T20:32:58Z
false
true
3
GO:0110040
110,040
nematode pharynx morphogenesis
biological_process
The process in which the anatomical structures of the nematode pharynx are generated and organized.
[ "GOC:rz", "PMID:20805556" ]
null
[]
[]
[]
[]
[]
[ "GO:0009887" ]
[]
[]
[]
[ "GO:0009887" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18285\" xsd:anyURI" ]
kmv
2017-07-24T20:51:28Z
false
true
7
GO:0110042
110,042
negative regulation of nematode pharynx morphogenesis
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of nematode pharynx morphogenesis.
[ "GOC:rz", "PMID:20805556" ]
null
[]
[]
[]
[]
[]
[ "GO:0110041", "GO:0110111" ]
[ "negatively_regulates GO:0110040" ]
[ "negatively_regulates" ]
[ "GO:0110040" ]
[ "GO:0110040", "GO:0110041", "GO:0110111" ]
[ "GO:0065007", "negatively_regulates GO:0110040" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18285\" xsd:anyURI" ]
kmv
2017-07-24T21:05:08Z
false
true
7
GO:0110044
110,044
regulation of cell cycle switching, mitotic to meiotic cell cycle
biological_process
Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.
[ "GOC:al", "PMID:17674143" ]
null
[ "sexual differentiation" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0007346", "GO:0010564", "GO:0051445" ]
[ "regulates GO:0051728" ]
[ "regulates" ]
[ "GO:0051728" ]
[ "GO:0007346", "GO:0010564", "GO:0051445", "GO:0051728" ]
[ "GO:0065007", "regulates GO:0051728" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20926\" xsd:anyURI" ]
kmv
2017-08-08T21:24:45Z
false
true
7
GO:0110045
110,045
negative regulation of cell cycle switching, mitotic to meiotic cell cycle
biological_process
Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.
[ "GOC:al", "PMID:17674143" ]
null
[]
[]
[]
[]
[]
[ "GO:0010948", "GO:0045931", "GO:0110044" ]
[ "negatively_regulates GO:0051728" ]
[ "negatively_regulates" ]
[ "GO:0051728" ]
[ "GO:0010948", "GO:0045931", "GO:0051728", "GO:0110044" ]
[ "GO:0065007", "negatively_regulates GO:0051728" ]
[]
[]
[]
[]
[]
kmv
2017-08-08T21:33:28Z
false
true
3
GO:0110050
110,050
deaminated glutathione amidase activity
molecular_function
Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H2O = 2-oxoglutarate + L-cysteinylglycine.
[ "GOC:ka", "PMID:28373563", "RHEA:54532" ]
N-(4-oxoglutarate)-L-cysteinylglycine = deaminated glutathione
[]
[]
[]
[]
[ "EC:3.5.1.128", "RHEA:54532" ]
[ "GO:0016811" ]
[]
[]
[]
[ "GO:0016811" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:3.5.1.128", "skos:exactMatch RHEA:54532", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23261\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
kmv
2017-08-31T19:19:11Z
false
true
5
GO:0110051
110,051
metabolite repair
biological_process
A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.
[ "GOC:ka", "PMID:23334546", "PMID:28373563" ]
null
[]
[]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[]
[]
[]
kmv
2017-09-08T15:16:01Z
false
true
2
GO:0110052
110,052
toxic metabolite repair
biological_process
A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.
[ "GOC:ka", "GOC:vw", "PMID:23334546" ]
null
[]
[]
[]
[]
[]
[ "GO:0110051", "GO:1990748" ]
[]
[]
[]
[ "GO:0110051", "GO:1990748" ]
[]
[]
[]
[]
[]
[]
kmv
2017-09-08T15:19:16Z
false
true
8
GO:0110053
110,053
regulation of actin filament organization
biological_process
Any process that modulates the frequency, rate or extent of actin filament organization.
[ "GOC:kmv" ]
null
[]
[]
[]
[]
[]
[ "GO:0032956", "GO:1902903" ]
[ "regulates GO:0007015" ]
[ "regulates" ]
[ "GO:0007015" ]
[ "GO:0007015", "GO:0032956", "GO:1902903" ]
[ "GO:0065007", "regulates GO:0007015" ]
[]
[]
[]
[]
[]
kmv
2017-09-20T19:52:57Z
false
true
8
GO:0110054
110,054
regulation of actin filament annealing
biological_process
Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
[ "GOC:mah", "PMID:10585915", "PMID:11575927", "PMID:15743909", "PMID:19244341" ]
null
[]
[]
[]
[]
[]
[ "GO:0110053" ]
[]
[]
[]
[ "GO:0110053" ]
[]
[]
[]
[]
[]
[]
kmv
2017-09-20T20:07:58Z
false
true
3
GO:0110055
110,055
negative regulation of actin filament annealing
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
[ "GOC:mah", "PMID:15743909" ]
null
[]
[]
[]
[]
[]
[ "GO:0110054" ]
[]
[]
[]
[ "GO:0110054" ]
[]
[]
[]
[]
[]
[]
kmv
2017-09-20T20:10:55Z
false
true
2
GO:0110057
110,057
regulation of blood vessel endothelial cell differentiation
biological_process
Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:23072816" ]
null
[]
[]
[]
[]
[]
[ "GO:0045601" ]
[ "regulates GO:0060837" ]
[ "regulates" ]
[ "GO:0060837" ]
[ "GO:0045601", "GO:0060837" ]
[ "GO:0065007", "regulates GO:0060837" ]
[]
[]
[]
[]
[]
kmv
2017-10-23T14:32:09Z
false
true
3
GO:0110058
110,058
positive regulation of blood vessel endothelial cell differentiation
biological_process
Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:23072816" ]
null
[]
[]
[]
[]
[]
[ "GO:0045603", "GO:0110057" ]
[ "positively_regulates GO:0060837" ]
[ "positively_regulates" ]
[ "GO:0060837" ]
[ "GO:0045603", "GO:0060837", "GO:0110057" ]
[ "GO:0065007", "positively_regulates GO:0060837" ]
[]
[]
[]
[]
[]
kmv
2017-10-23T14:38:19Z
false
true
7
GO:0110059
110,059
negative regulation of blood vessel endothelial cell differentiation
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:23072816" ]
null
[]
[]
[]
[]
[]
[ "GO:0045602", "GO:0110057" ]
[ "negatively_regulates GO:0060837" ]
[ "negatively_regulates" ]
[ "GO:0060837" ]
[ "GO:0045602", "GO:0060837", "GO:0110057" ]
[ "GO:0065007", "negatively_regulates GO:0060837" ]
[]
[]
[]
[]
[]
kmv
2017-10-23T14:47:29Z
false
true
7
GO:0110061
110,061
regulation of angiotensin-activated signaling pathway
biological_process
Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway.
[ "GOC:lf", "PMID:28784619" ]
null
[]
[]
[]
[]
[]
[ "GO:0008277" ]
[ "regulates GO:0038166" ]
[ "regulates" ]
[ "GO:0038166" ]
[ "GO:0008277", "GO:0038166" ]
[ "GO:0065007", "regulates GO:0038166" ]
[]
[]
[]
[]
[]
kmv
2017-10-26T17:37:37Z
false
true
9
GO:0110062
110,062
negative regulation of angiotensin-activated signaling pathway
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway.
[ "GOC:lf", "PMID:28784619" ]
null
[]
[]
[]
[]
[]
[ "GO:0045744", "GO:0110061" ]
[ "negatively_regulates GO:0038166" ]
[ "negatively_regulates" ]
[ "GO:0038166" ]
[ "GO:0038166", "GO:0045744", "GO:0110061" ]
[ "GO:0065007", "negatively_regulates GO:0038166" ]
[]
[]
[]
[]
[]
kmv
2017-10-26T17:42:17Z
false
true
3
GO:0110063
110,063
positive regulation of angiotensin-activated signaling pathway
biological_process
Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway.
[ "GOC:lf", "PMID:28784619" ]
null
[]
[]
[]
[]
[]
[ "GO:0045745", "GO:0110061" ]
[ "positively_regulates GO:0038166" ]
[ "positively_regulates" ]
[ "GO:0038166" ]
[ "GO:0038166", "GO:0045745", "GO:0110061" ]
[ "GO:0065007", "positively_regulates GO:0038166" ]
[]
[]
[]
[]
[]
kmv
2017-10-26T17:47:37Z
false
true
8
GO:0110064
110,064
lncRNA catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length.
[ "GOC:al", "PMID:24493644" ]
null
[ "lncRNA breakdown", "lncRNA catabolism", "lncRNA degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006401" ]
[]
[]
[]
[ "GO:0006401" ]
[]
[]
[]
[]
[]
[]
kmv
2017-11-06T13:49:49Z
false
true
5
GO:0110065
110,065
regulation of interphase mitotic telomere clustering
biological_process
Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.
[ "GOC:vw", "PMID:25778919" ]
null
[ "regulation of mitotic telomere clustering during interphase" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032879" ]
[ "regulates GO:0120110" ]
[ "regulates" ]
[ "GO:0120110" ]
[ "GO:0032879", "GO:0120110" ]
[ "GO:0065007", "regulates GO:0120110" ]
[]
[]
[]
[]
[]
kmv
2017-11-17T22:03:40Z
false
true
4
GO:0110066
110,066
negative regulation of interphase mitotic telomere clustering
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase.
[ "GOC:vw", "PMID:25778919" ]
null
[ "negative regulation of mitotic telomere clustering during interphase", "telomere dispersion during interphase" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0048519", "GO:0110065" ]
[ "negatively_regulates GO:0120110" ]
[ "negatively_regulates" ]
[ "GO:0120110" ]
[ "GO:0048519", "GO:0110065", "GO:0120110" ]
[ "GO:0065007", "negatively_regulates GO:0120110" ]
[]
[]
[]
[]
[]
kmv
2017-11-17T22:11:59Z
false
true
8
GO:0110067
110,067
ammonium transmembrane transporter complex
cellular_component
High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other.
[ "GOC:bhm", "PMID:17026539", "PMID:23463773" ]
null
[ "AMT1 complex" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:1902495" ]
[]
[]
[]
[ "GO:1902495" ]
[]
[]
[]
[]
[]
[]
kmv
2017-11-20T15:21:10Z
false
true
8
GO:0110068
110,068
glucosylglycerate phosphorylase activity
molecular_function
Catalysis of the reaction: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + phosphate = (R)-glycerate + alpha-D-glucose 1-phosphate.
[ "PMID:28754708", "RHEA:55268" ]
null
[]
[]
[]
[]
[ "EC:2.4.1.352", "MetaCyc:RXN-18999", "RHEA:55268" ]
[ "GO:0004645" ]
[]
[]
[]
[ "GO:0004645" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.4.1.352", "skos:exactMatch MetaCyc:RXN-18999", "skos:exactMatch RHEA:55268", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30910\" xsd:anyURI" ]
kmv
2017-11-21T21:50:10Z
false
true
2
GO:0110069
110,069
syncytial embryo cellularization
biological_process
The separation of a syncytial embryo into individual cells.
[ "GOC:ha", "PMID:27226317" ]
null
[]
[]
[]
[]
[]
[ "GO:0007349", "GO:0051301" ]
[ "part_of GO:0009790" ]
[ "part_of" ]
[ "GO:0009790" ]
[ "GO:0007349", "GO:0009790", "GO:0051301" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14543\" xsd:anyURI" ]
kmv
2017-11-22T19:59:19Z
false
true
6
GO:0110070
110,070
cellularization cleavage furrow
cellular_component
A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells.
[ "GOC:ha", "PMID:27226317" ]
null
[]
[]
[]
[]
[]
[ "GO:0098590" ]
[]
[]
[]
[ "GO:0098590" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14543\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21737\" xsd:anyURI" ]
kmv
2017-11-22T20:10:14Z
false
true
4
GO:0110071
110,071
cellularization cleavage furrow invagination front
cellular_component
The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane.
[ "GOC:ha", "PMID:27226317" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0110070" ]
[ "part_of" ]
[ "GO:0110070" ]
[ "GO:0110070", "GO:0110165" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14543\" xsd:anyURI" ]
kmv
2017-11-22T20:13:21Z
false
true
7
GO:0110072
110,072
apical constriction involved in ventral furrow formation
biological_process
The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.
[ "GOC:ha", "PMID:28495958" ]
null
[]
[]
[]
[]
[]
[ "GO:0003384" ]
[ "part_of GO:0007370" ]
[ "part_of" ]
[ "GO:0007370" ]
[ "GO:0003384", "GO:0007370" ]
[ "GO:0003383", "part_of GO:0007370" ]
[]
[]
[]
[]
[]
kmv
2017-12-06T17:04:49Z
false
true
8
GO:0110073
110,073
regulation of apical constriction involved in ventral furrow formation
biological_process
Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation.
[ "GOC:ha", "PMID:28495958" ]
null
[]
[]
[]
[]
[]
[ "GO:0010470", "GO:0022604", "GO:1903115" ]
[ "regulates GO:0110072" ]
[ "regulates" ]
[ "GO:0110072" ]
[ "GO:0010470", "GO:0022604", "GO:0110072", "GO:1903115" ]
[ "GO:0065007", "regulates GO:0110072" ]
[]
[]
[]
[]
[]
kmv
2017-12-06T17:30:29Z
false
true
1
GO:0110074
110,074
positive regulation of apical constriction involved in ventral furrow formation
biological_process
Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation.
[ "GOC:ha", "PMID:28495958" ]
null
[]
[]
[]
[]
[]
[ "GO:0110073", "GO:1903116" ]
[ "positively_regulates GO:0110072" ]
[ "positively_regulates" ]
[ "GO:0110072" ]
[ "GO:0110072", "GO:0110073", "GO:1903116" ]
[ "GO:0065007", "positively_regulates GO:0110072" ]
[]
[]
[]
[]
[]
kmv
2017-12-06T17:39:00Z
false
true
5
GO:0110075
110,075
regulation of ferroptosis
biological_process
Any process that modulates the frequency, rate or extent of ferroptosis.
[ "GOC:sp", "PMID:24439385", "PMID:25402683", "PMID:29290465" ]
null
[]
[]
[]
[]
[]
[ "GO:0043067" ]
[ "regulates GO:0097707" ]
[ "regulates" ]
[ "GO:0097707" ]
[ "GO:0043067", "GO:0097707" ]
[ "GO:0065007", "regulates GO:0097707" ]
[]
[]
[]
[]
[]
kmv
2018-01-11T17:51:48Z
false
true
8
GO:0110077
110,077
vesicle-mediated intercellular transport
biological_process
A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.
[ "GOC:sp", "PMID:29328915", "PMID:29328916" ]
null
[ "endosomal trafficking" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0010496", "GO:0016192" ]
[]
[]
[]
[ "GO:0010496", "GO:0016192" ]
[]
[]
[]
[]
[]
[]
kmv
2018-01-29T14:46:52Z
false
true
6
GO:0110078
110,078
TTT Hsp90 cochaperone complex
cellular_component
A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family.
[ "PMID:20810650", "PMID:22505622", "PMID:28827813", "PMID:34233195" ]
null
[ "Tel2-Tti1-Tti2", "TELO2-TTI1-TTI2", "Triple T complex", "TTT complex" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26026\" xsd:anyURI" ]
kmv
2018-01-29T21:39:52Z
false
true
1
GO:0110080
110,080
positive regulation of placenta blood vessel development
biological_process
Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:27748453" ]
null
[]
[]
[]
[]
[]
[ "GO:0051094", "GO:0110079" ]
[ "positively_regulates GO:0060674" ]
[ "positively_regulates" ]
[ "GO:0060674" ]
[ "GO:0051094", "GO:0060674", "GO:0110079" ]
[ "GO:0065007", "positively_regulates GO:0060674" ]
[]
[]
[]
[]
[]
kmv
2018-02-01T14:55:30Z
false
true
1
GO:0110081
110,081
negative regulation of placenta blood vessel development
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:27748453" ]
null
[]
[]
[]
[]
[]
[ "GO:0051093", "GO:0110079" ]
[ "negatively_regulates GO:0060674" ]
[ "negatively_regulates" ]
[ "GO:0060674" ]
[ "GO:0051093", "GO:0060674", "GO:0110079" ]
[ "GO:0065007", "negatively_regulates GO:0060674" ]
[]
[]
[]
[]
[]
kmv
2018-02-01T15:01:11Z
false
true
6
GO:0110082
110,082
regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly
biological_process
Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
[ "GOC:vw", "PMID:29343550" ]
null
[]
[]
[]
[]
[]
[ "GO:1901900" ]
[ "regulates GO:1903476" ]
[ "regulates" ]
[ "GO:1903476" ]
[ "GO:1901900", "GO:1903476" ]
[ "GO:0065007", "regulates GO:1903476" ]
[]
[]
[]
[]
[]
kmv
2018-02-01T19:25:06Z
false
true
9
GO:0110083
110,083
positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly
biological_process
Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
[ "GOC:vw", "PMID:29343550" ]
null
[]
[]
[]
[]
[]
[ "GO:0110082", "GO:1903829" ]
[ "positively_regulates GO:1903476" ]
[ "positively_regulates" ]
[ "GO:1903476" ]
[ "GO:0110082", "GO:1903476", "GO:1903829" ]
[ "GO:0065007", "positively_regulates GO:1903476" ]
[]
[]
[]
[]
[]
kmv
2018-02-01T19:30:03Z
false
true
7
GO:0110084
110,084
obsolete negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly
biological_process
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
[ "GOC:vw", "PMID:29343550" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:1903475" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
kmv
2018-02-01T19:33:51Z
true
true
8
GO:0110085
110,085
mitotic actomyosin contractile ring
cellular_component
A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centri...
[ "GOC:vw", "PMID:27505246" ]
null
[]
[]
[]
[]
[]
[ "GO:0005826" ]
[]
[]
[]
[ "GO:0005826" ]
[]
[]
[]
[]
[]
[]
kmv
2018-02-12T17:04:02Z
false
true
3
GO:0110086
110,086
meiotic actomyosin contractile ring
cellular_component
A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centri...
[ "GOC:vw", "PMID:22526418" ]
null
[]
[]
[]
[]
[]
[ "GO:0005826" ]
[]
[]
[]
[ "GO:0005826" ]
[]
[]
[]
[]
[]
[]
kmv
2018-02-12T17:26:17Z
false
true
4
GO:0110087
110,087
obsolete suppression by virus of host protease activator activity
biological_process
OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protease activator activity.
[ "PMID:23303392" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22163\" xsd:anyURI" ]
kmv
2018-02-12T20:17:29Z
true
true
4
GO:0110088
110,088
hippocampal neuron apoptotic process
biological_process
Any apoptotic process that occurs in a hippocampal neuron.
[ "GOC:sl", "PMID:18940801" ]
null
[]
[]
[]
[]
[]
[ "GO:0051402" ]
[]
[]
[]
[ "GO:0051402" ]
[]
[]
[]
[]
[]
[]
kmv
2018-02-13T21:06:23Z
false
true
6
GO:0110089
110,089
regulation of hippocampal neuron apoptotic process
biological_process
Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.
[ "GOC:sl", "PMID:18940801" ]
null
[]
[]
[]
[]
[]
[ "GO:0043523" ]
[ "regulates GO:0110088" ]
[ "regulates" ]
[ "GO:0110088" ]
[ "GO:0043523", "GO:0110088" ]
[ "GO:0065007", "regulates GO:0110088" ]
[]
[]
[]
[]
[]
kmv
2018-02-13T21:18:29Z
false
true
6