go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0110090
110,090
positive regulation of hippocampal neuron apoptotic process
biological_process
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.
[ "GOC:sl", "PMID:18940801" ]
null
[]
[]
[]
[]
[]
[ "GO:0043525", "GO:0110089" ]
[ "positively_regulates GO:0110088" ]
[ "positively_regulates" ]
[ "GO:0110088" ]
[ "GO:0043525", "GO:0110088", "GO:0110089" ]
[ "GO:0065007", "positively_regulates GO:0110088" ]
[]
[]
[]
[]
[]
kmv
2018-02-13T21:22:18Z
false
true
7
GO:0110092
110,092
nucleus leading edge
cellular_component
The area of a motile nucleus closest to the direction of movement.
[ "GOC:al", "GOC:mah", "GOC:vw", "PMID:15030757", "PMID:24335254" ]
null
[ "horsetail nucleus leading edge" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005634" ]
[ "part_of" ]
[ "GO:0005634" ]
[ "GO:0005634", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
kmv
2018-02-14T22:39:58Z
false
true
7
GO:0110093
110,093
nucleus lagging edge
cellular_component
The area of a motile nucleus furthest from the direction of movement.
[ "GOC:kmv", "PMID:24335254" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005634" ]
[ "part_of" ]
[ "GO:0005634" ]
[ "GO:0005634", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
kmv
2018-02-14T22:56:12Z
false
true
5
GO:0110094
110,094
polyphosphate-mediated signaling
biological_process
Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.
[ "GOC:rjd", "PMID:27519410", "PMID:28584190" ]
null
[ "polyphosphate signaling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007267" ]
[]
[]
[]
[ "GO:0007267" ]
[]
[]
[]
[]
[]
[]
kmv
2018-02-15T16:42:30Z
false
true
8
GO:0110095
110,095
cellular detoxification of aldehyde
biological_process
Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
[ "GOC:vw", "PMID:25656103" ]
null
[]
[]
[]
[]
[]
[ "GO:1990748" ]
[ "part_of GO:0110096" ]
[ "part_of" ]
[ "GO:0110096" ]
[ "GO:0110096", "GO:1990748" ]
[]
[]
[]
[]
[]
[]
kmv
2018-02-16T21:19:20Z
false
true
7
GO:0110096
110,096
cellular response to aldehyde
biological_process
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.
[ "GOC:vw", "PMID:25656103" ]
null
[]
[]
[]
[]
[]
[ "GO:1901701" ]
[]
[]
[]
[ "GO:1901701" ]
[]
[]
[]
[]
[]
[]
kmv
2018-02-16T21:29:18Z
false
true
1
GO:0110097
110,097
regulation of calcium import into the mitochondrion
biological_process
Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion.
[ "GOC:sl", "PMID:24085037" ]
null
[]
[]
[]
[]
[]
[ "GO:1903169" ]
[ "regulates GO:0036444" ]
[ "regulates" ]
[ "GO:0036444" ]
[ "GO:0036444", "GO:1903169" ]
[ "GO:0065007", "regulates GO:0036444" ]
[]
[]
[]
[]
[]
kmv
2018-02-28T00:33:51Z
false
true
4
GO:0110098
110,098
positive regulation of calcium import into the mitochondrion
biological_process
Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.
[ "GOC:sl", "PMID:24085037" ]
null
[]
[]
[]
[]
[]
[ "GO:0110097", "GO:1904427" ]
[ "positively_regulates GO:0036444" ]
[ "positively_regulates" ]
[ "GO:0036444" ]
[ "GO:0036444", "GO:0110097", "GO:1904427" ]
[ "GO:0065007", "positively_regulates GO:0036444" ]
[]
[]
[]
[]
[]
kmv
2018-02-28T00:39:13Z
false
true
1
GO:0110099
110,099
negative regulation of calcium import into the mitochondrion
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.
[ "GOC:sl", "PMID:24085037" ]
null
[]
[]
[]
[]
[]
[ "GO:0110097", "GO:1903170" ]
[ "negatively_regulates GO:0036444" ]
[ "negatively_regulates" ]
[ "GO:0036444" ]
[ "GO:0036444", "GO:0110097", "GO:1903170" ]
[ "GO:0065007", "negatively_regulates GO:0036444" ]
[]
[]
[]
[]
[]
kmv
2018-02-28T00:42:06Z
false
true
4
GO:0110100
110,100
spindle pole body separation
biological_process
The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are acr...
[ "GOC:vw" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
[]
[]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0022402" ]
[ "part_of GO:0051300" ]
[ "part_of" ]
[ "GO:0051300" ]
[ "GO:0022402", "GO:0051300" ]
[]
[]
[]
[]
[]
[]
kmv
2018-03-06T15:09:28Z
false
true
4
GO:0110101
110,101
L-valine transmembrane import into vacuole
biological_process
The directed movement of L-valine into the vacuole across the vacuolar membrane.
[ "GOC:al", "PMID:20944394" ]
null
[]
[]
[]
[]
[]
[ "GO:0034491", "GO:1903785" ]
[]
[]
[]
[ "GO:0034491", "GO:1903785" ]
[]
[]
[]
[]
[]
[]
kmv
2018-03-14T19:56:06Z
false
true
2
GO:0110102
110,102
ribulose bisphosphate carboxylase complex assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex.
[ "GOC:krc", "GOC:tb", "PMID:29396988", "PMID:29589905" ]
null
[ "RuBisCO assembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19828\" xsd:anyURI" ]
kmv
2018-03-15T17:24:14Z
false
true
8
GO:0110103
110,103
RNA polymerase II termination complex
cellular_component
A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end.
[ "GOC:lnp", "PMID:23200120", "PMID:25722373" ]
In S. cerevisiae, this complex is formed by RAI1 and RAT1; in H. sapiens it is formed by Twi12, Xrn2 and Tan1.
[ "TXT complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0140513", "GO:1905354" ]
[]
[]
[]
[ "GO:0140513", "GO:1905354" ]
[]
[]
[]
[]
[]
[]
kmv
2018-03-16T18:55:17Z
false
true
6
GO:0110104
110,104
mRNA alternative polyadenylation
biological_process
The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).
[ "GOC:ans", "PMID:28453393", "PMID:29276085" ]
null
[]
[]
[]
[]
[]
[ "GO:0031124" ]
[]
[]
[]
[ "GO:0031124" ]
[]
[]
[]
[]
[]
[]
kmv
2018-03-27T19:26:56Z
false
true
9
GO:0110105
110,105
mRNA cleavage and polyadenylation specificity factor complex assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex.
[ "GOC:mah", "PMID:27401558" ]
null
[]
[]
[]
[]
[]
[ "GO:0065003" ]
[ "part_of GO:0031123" ]
[ "part_of" ]
[ "GO:0031123" ]
[ "GO:0031123", "GO:0065003" ]
[]
[]
[]
[]
[]
[]
kmv
2018-04-13T19:05:17Z
false
true
4
GO:0110107
110,107
regulation of imaginal disc-derived wing vein specification
biological_process
Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification.
[ "GOC:ha", "PMID:11861482" ]
null
[]
[]
[]
[]
[]
[ "GO:0051239" ]
[ "regulates GO:0007474" ]
[ "regulates" ]
[ "GO:0007474" ]
[ "GO:0007474", "GO:0051239" ]
[ "GO:0065007", "regulates GO:0007474" ]
[]
[]
[]
[]
[]
kmv
2018-07-05T13:44:08Z
false
true
1
GO:0110109
110,109
negative regulation of imaginal disc-derived wing vein specification
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification.
[ "GOC:ha", "PMID:11861482" ]
null
[]
[]
[]
[]
[]
[ "GO:0051241", "GO:0110107" ]
[ "negatively_regulates GO:0007474" ]
[ "negatively_regulates" ]
[ "GO:0007474" ]
[ "GO:0007474", "GO:0051241", "GO:0110107" ]
[ "GO:0065007", "negatively_regulates GO:0007474" ]
[]
[]
[]
[]
[]
kmv
2018-07-05T13:55:37Z
false
true
7
GO:0110110
110,110
positive regulation of animal organ morphogenesis
biological_process
Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.
[ "GOC:kmv" ]
null
[]
[]
[]
[]
[]
[ "GO:0051094", "GO:0051240", "GO:2000027" ]
[ "positively_regulates GO:0009887" ]
[ "positively_regulates" ]
[ "GO:0009887" ]
[ "GO:0009887", "GO:0051094", "GO:0051240", "GO:2000027" ]
[ "GO:0065007", "positively_regulates GO:0009887" ]
[]
[]
[]
[]
[]
kmv
2018-07-05T14:10:14Z
false
true
9
GO:0110111
110,111
negative regulation of animal organ morphogenesis
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.
[ "GOC:kmv" ]
null
[]
[]
[]
[]
[]
[ "GO:0051093", "GO:0051241", "GO:2000027" ]
[ "negatively_regulates GO:0009887" ]
[ "negatively_regulates" ]
[ "GO:0009887" ]
[ "GO:0009887", "GO:0051093", "GO:0051241", "GO:2000027" ]
[ "GO:0065007", "negatively_regulates GO:0009887" ]
[]
[]
[]
[]
[]
kmv
2018-07-05T14:25:21Z
false
true
8
GO:0110114
110,114
obsolete negative regulation of lipid transporter activity
biological_process
OBSOLETE. Any process that decreases the frequency, rate, or extent of lipid transporter activity.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:27365390" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]
kmv
2018-07-06T19:21:44Z
true
true
5
GO:0110115
110,115
Cdr2 medial cortical node complex
cellular_component
A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase.
[ "GOC:vw", "PMID:29514920" ]
null
[ "interphase cortical node", "interphase node" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1902911" ]
[ "part_of GO:0071341" ]
[ "part_of" ]
[ "GO:0071341" ]
[ "GO:0071341", "GO:1902911" ]
[]
[]
[]
[]
[]
[]
kmv
2018-07-10T14:02:26Z
false
true
9
GO:0110117
110,117
positive regulation of compound eye photoreceptor cell differentiation
biological_process
Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.
[ "GOC:ha", "PMID:16377567" ]
null
[]
[]
[]
[]
[]
[ "GO:0046534", "GO:0110116" ]
[ "positively_regulates GO:0001751" ]
[ "positively_regulates" ]
[ "GO:0001751" ]
[ "GO:0001751", "GO:0046534", "GO:0110116" ]
[ "GO:0065007", "positively_regulates GO:0001751" ]
[]
[]
[]
[]
[]
kmv
2018-07-16T18:13:28Z
false
true
1
GO:0110118
110,118
negative regulation of compound eye photoreceptor cell differentiation
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.
[ "GOC:ha", "PMID:16377567" ]
null
[]
[]
[]
[]
[]
[ "GO:0046533", "GO:0110116" ]
[ "negatively_regulates GO:0001751" ]
[ "negatively_regulates" ]
[ "GO:0001751" ]
[ "GO:0001751", "GO:0046533", "GO:0110116" ]
[ "GO:0065007", "negatively_regulates GO:0001751" ]
[]
[]
[]
[]
[]
kmv
2018-07-16T18:15:52Z
false
true
9
GO:0110119
110,119
positive regulation of very-low-density lipoprotein particle clearance
biological_process
Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph", "PMID:25510864" ]
null
[]
[]
[]
[]
[]
[ "GO:0010915", "GO:0010986" ]
[ "positively_regulates GO:0034447" ]
[ "positively_regulates" ]
[ "GO:0034447" ]
[ "GO:0010915", "GO:0010986", "GO:0034447" ]
[ "GO:0065007", "positively_regulates GO:0034447" ]
[]
[]
[]
[]
[]
kmv
2018-07-27T14:13:47Z
false
true
5
GO:0110121
110,121
gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body
biological_process
Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body.
[ "GOC:vw", "PMID:19001497" ]
null
[]
[]
[]
[]
[]
[ "GO:1990735" ]
[]
[]
[]
[ "GO:1990735" ]
[]
[]
[]
[]
[]
[]
kmv
2018-07-27T15:49:05Z
false
true
6
GO:0110122
110,122
myotube cell migration
biological_process
The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse.
[ "GOC:ha", "PMID:29122742" ]
null
[]
[]
[]
[]
[]
[ "GO:0014812" ]
[]
[]
[]
[ "GO:0014812" ]
[]
[]
[]
[]
[]
[]
kmv
2018-08-22T20:58:09Z
false
true
8
GO:0110123
110,123
regulation of myotube cell migration
biological_process
Any process that modulates the frequency, rate or extent of myotube cell migration.
[ "GOC:ha", "PMID:29122742" ]
null
[]
[]
[]
[]
[]
[ "GO:0030334" ]
[ "regulates GO:0110122" ]
[ "regulates" ]
[ "GO:0110122" ]
[ "GO:0030334", "GO:0110122" ]
[ "GO:0065007", "regulates GO:0110122" ]
[]
[]
[]
[]
[]
kmv
2018-08-22T21:06:53Z
false
true
1
GO:0110124
110,124
positive regulation of myotube cell migration
biological_process
Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.
[ "GOC:ha", "PMID:29122742" ]
null
[]
[]
[]
[]
[]
[ "GO:0030335", "GO:0110123" ]
[ "positively_regulates GO:0110122" ]
[ "positively_regulates" ]
[ "GO:0110122" ]
[ "GO:0030335", "GO:0110122", "GO:0110123" ]
[ "GO:0065007", "positively_regulates GO:0110122" ]
[]
[]
[]
[]
[]
kmv
2018-08-22T21:09:38Z
false
true
2
GO:0110125
110,125
negative regulation of myotube cell migration
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.
[ "GOC:ha", "PMID:29122742" ]
null
[]
[]
[]
[]
[]
[ "GO:0030336", "GO:0110123" ]
[ "negatively_regulates GO:0110122" ]
[ "negatively_regulates" ]
[ "GO:0110122" ]
[ "GO:0030336", "GO:0110122", "GO:0110123" ]
[ "GO:0065007", "negatively_regulates GO:0110122" ]
[]
[]
[]
[]
[]
kmv
2018-08-22T21:12:47Z
false
true
1
GO:0110126
110,126
phloem loading
biological_process
The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
[ "GOC:lr", "PMID:19025382" ]
null
[]
[]
[]
[]
[]
[ "GO:0010233" ]
[]
[]
[]
[ "GO:0010233" ]
[]
[]
[]
[]
[]
[]
kmv
2018-09-07T21:24:54Z
false
true
6
GO:0110127
110,127
phloem unloading
biological_process
The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.
[ "GOC:lr", "PMID:19025382" ]
null
[]
[]
[]
[]
[]
[ "GO:0010233" ]
[]
[]
[]
[ "GO:0010233" ]
[]
[]
[]
[]
[]
[]
kmv
2018-09-07T21:33:07Z
false
true
2
GO:0110128
110,128
phloem sucrose unloading
biological_process
The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.
[ "GOC:lr", "PMID:30018170" ]
null
[]
[]
[]
[]
[]
[ "GO:0015770", "GO:0110127" ]
[]
[]
[]
[ "GO:0015770", "GO:0110127" ]
[]
[]
[]
[]
[]
[]
kmv
2018-09-07T21:38:52Z
false
true
8
GO:0110129
110,129
obsolete SHREC2 complex
cellular_component
OBSOLETE. A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subun...
[ "GOC:mah", "PMID:19111658" ]
This term was added in error.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23685\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26068\" xsd:anyURI" ]
kmv
2018-09-25T21:25:41Z
true
true
6
GO:0110130
110,130
ribitol-5-phosphatase activity
molecular_function
Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate.
[ "GOC:rn", "PMID:30240188" ]
null
[]
[]
[]
[]
[ "RHEA:47648" ]
[ "GO:0016791" ]
[]
[]
[]
[ "GO:0016791" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:47648", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
kmv
2018-10-08T19:47:57Z
false
true
9
GO:0110131
110,131
Aim21-Tda2 complex
cellular_component
A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables.
[ "GOC:rn", "PMID:28706108", "PMID:29467252" ]
null
[ "Aim21/Tda2 complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[ "part_of GO:0030479" ]
[ "part_of" ]
[ "GO:0030479" ]
[ "GO:0030479", "GO:0032991" ]
[]
[]
[]
[]
[]
[]
kmv
2018-10-09T21:08:36Z
false
true
1
GO:0110132
110,132
obsolete regulation of CRISPR-cas system
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of a CRISPR-cas system.
[ "PMID:30190307", "PMID:30190308" ]
This term was obsoleted because it does not accurately capture the process described in the literature.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16423\" xsd:anyURI" ]
kmv
2018-11-14T17:13:16Z
true
true
1
GO:0110133
110,133
obsolete negative regulation of CRISPR-cas system
biological_process
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a CRISPR-cas system.
[ "PMID:30190307", "PMID:30190308" ]
This term was obsoleted because it does not accurately capture the process described in the literature.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0098672" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/16423\" xsd:anyURI" ]
kmv
2018-11-14T17:23:07Z
true
true
1
GO:0110134
110,134
meiotic drive
biological_process
A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in o...
[ "GOC:mah", "PMID:26920473", "PMID:29322557", "PMID:29499907" ]
null
[]
[]
[]
[ "goslim_pombe" ]
[]
[ "GO:0022414" ]
[]
[]
[]
[ "GO:0022414" ]
[]
[]
[]
[]
[]
[]
kmv
2019-01-02T17:37:09Z
false
true
4
GO:0110136
110,136
protein-RNA complex remodeling
biological_process
The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex.
[ "GOC:rn", "PMID:19737519", "PMID:20542003", "PMID:24240281" ]
null
[ "protein-RNA complex remodelling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0034367", "GO:0071826" ]
[]
[]
[]
[ "GO:0034367", "GO:0071826" ]
[]
[]
[]
[]
[]
[]
kmv
2019-01-22T19:23:17Z
false
true
3
GO:0110138
110,138
positive regulation of imaginal disc-derived leg joint morphogenesis
biological_process
Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.
[ "GOC:ha", "PMID:25329825" ]
null
[]
[]
[]
[]
[]
[ "GO:0051094", "GO:0110137" ]
[ "positively_regulates GO:0007480" ]
[ "positively_regulates" ]
[ "GO:0007480" ]
[ "GO:0007480", "GO:0051094", "GO:0110137" ]
[ "GO:0065007", "positively_regulates GO:0007480" ]
[]
[]
[]
[]
[]
kmv
2019-02-12T15:37:05Z
false
true
8
GO:0110139
110,139
negative regulation of imaginal disc-derived leg joint morphogenesis
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.
[ "GOC:ha", "PMID:25329825" ]
null
[]
[]
[]
[]
[]
[ "GO:0051093", "GO:0110137" ]
[ "negatively_regulates GO:0007480" ]
[ "negatively_regulates" ]
[ "GO:0007480" ]
[ "GO:0007480", "GO:0051093", "GO:0110137" ]
[ "GO:0065007", "negatively_regulates GO:0007480" ]
[]
[]
[]
[]
[]
kmv
2019-02-12T15:40:09Z
false
true
6
GO:0110140
110,140
flagellum attachment zone organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid spe...
[ "GOC:ach", "PMID:26776656" ]
null
[ "FAZ organization", "flagellum attachment zone organisation" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0034330" ]
[]
[]
[]
[ "GO:0034330" ]
[]
[]
[]
[]
[]
[]
kmv
2019-03-04T19:55:50Z
false
true
6
GO:0110141
110,141
L-glutamate import into mitochondrion
biological_process
The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix.
[ "GOC:vw", "PMID:30297026" ]
null
[]
[]
[]
[]
[]
[ "GO:0010496", "GO:0015813" ]
[]
[]
[]
[ "GO:0010496", "GO:0015813" ]
[]
[]
[]
[]
[]
[]
kmv
2019-04-24T19:13:46Z
false
true
9
GO:0110142
110,142
ubiquinone biosynthesis complex
cellular_component
A protein complex composed of enzymes and accessory factors of the ubiquinone (CoQ) biosynthesis pathway. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K. In eukaryotes, the complex is located on the matrix face of the inner mitochondrial membrane and includes COQ3, COQ4, COQ5, COQ6, CO...
[ "GOC:imk", "PMID:27060254", "PMID:28927698", "PMID:30686758" ]
null
[ "complex Q", "CoQ Biosynthetic Complex", "CoQ metabolon", "CoQ-synthome", "Ubi complex" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1902494" ]
[]
[]
[]
[ "GO:1902494" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27958\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28022\" xsd:anyURI" ]
kmv
2019-04-25T15:48:21Z
false
true
7
GO:0110143
110,143
magnetosome
cellular_component
A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane...
[ "GOC:aa", "PMID:27620945" ]
null
[]
[]
[]
[]
[]
[ "GO:0043231" ]
[]
[]
[]
[ "GO:0043231" ]
[]
[]
[]
[]
[]
[]
kmv
2019-05-30T17:31:21Z
false
true
4
GO:0110144
110,144
obsolete magnetosome part
cellular_component
OBSOLETE. Any constituent part of a magnetosome, a membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria.
[ "GOC:aa", "PMID:27620945" ]
null
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0110143" ]
[]
kmv
2019-05-30T17:36:02Z
true
true
5
GO:0110145
110,145
magnetosome lumen
cellular_component
The volume enclosed by the membrane of a magnetosome.
[ "GOC:aa", "PMID:27620945" ]
null
[]
[]
[]
[]
[]
[ "GO:0070013" ]
[ "part_of GO:0110143" ]
[ "part_of" ]
[ "GO:0110143" ]
[ "GO:0070013", "GO:0110143" ]
[ "GO:0031974", "part_of GO:0110143" ]
[]
[]
[]
[]
[]
kmv
2019-05-30T17:42:14Z
false
true
9
GO:0110146
110,146
magnetosome membrane
cellular_component
The lipid bilayer surrounding a magnetosome.
[ "GOC:aa", "PMID:27620945" ]
null
[]
[]
[]
[]
[]
[ "GO:0031090" ]
[ "part_of GO:0110143" ]
[ "part_of" ]
[ "GO:0110143" ]
[ "GO:0031090", "GO:0110143" ]
[ "GO:0016020", "part_of GO:0110143" ]
[]
[]
[]
[]
[]
kmv
2019-05-30T17:51:09Z
false
true
7
GO:0110147
110,147
obsolete protein maturation by nickel ion transfer
biological_process
OBSOLETE. A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation.
[ "GOC:al", "PMID:24115911" ]
The reason for obsoletion is that these BP terms represent MFs.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0051604" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29105\" xsd:anyURI" ]
kmv
2019-05-31T14:41:20Z
true
true
3
GO:0110149
110,149
obsolete regulation of biomineralization
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.
[ "PMID:22992051" ]
This term was obsoleted because it grouped multicellular organism processes and cellular processes.
[ "regulation of biomineral formation", "regulation of biomineralisation", "regulation of mineralisation", "regulation of mineralization" ]
[ "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24213\" xsd:anyURI" ]
kmv
2019-06-10T18:06:59Z
true
true
6
GO:0110150
110,150
obsolete negative regulation of biomineralization
biological_process
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.
[ "PMID:22992051" ]
This term was obsoleted because it grouped multicellular organism processes and cellular processes.
[ "negative regulation of biomineral formation", "negative regulation of biomineralisation", "negative regulation of mineralisation", "negative regulation of mineralization" ]
[ "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24213\" xsd:anyURI" ]
kmv
2019-06-10T18:12:24Z
true
true
2
GO:0110151
110,151
obsolete positive regulation of biomineralization
biological_process
OBSOLETE. Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.
[ "PMID:22992051" ]
This term was obsoleted because it grouped multicellular organism processes and cellular processes.
[ "positive regulation of biomineral formation", "positive regulation of biomineralisation", "positive regulation of mineralisation", "positive regulation of mineralization" ]
[ "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24213\" xsd:anyURI" ]
kmv
2019-06-10T18:18:01Z
true
true
8
GO:0110152
110,152
RNA NAD+-cap (NAD+-forming) hydrolase activity
molecular_function
Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+.
[ "GOC:sp", "PMID:28283058", "RHEA:60880" ]
This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
[ "RNA NAD-cap (NAD-forming) hydrolase activity" ]
[ "EXACT" ]
[]
[]
[ "RHEA:60880" ]
[ "GO:0016818", "GO:0140098" ]
[]
[]
[]
[ "GO:0016818", "GO:0140098" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:60880", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17594\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27180\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
kmv
2019-07-08T15:55:11Z
false
true
2
GO:0110153
110,153
RNA NAD-cap (NMN-forming) hydrolase activity
molecular_function
Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H+.
[ "GOC:sp", "PMID:25533955", "PMID:31101919", "RHEA:60876" ]
This reaction specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.
[]
[]
[]
[]
[ "RHEA:60876" ]
[ "GO:0016462", "GO:0140098" ]
[]
[]
[]
[ "GO:0016462", "GO:0140098" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:60876", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17594\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23401\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
kmv
2019-07-08T17:15:59Z
false
true
6
GO:0110154
110,154
RNA decapping
biological_process
Cleavage of the 5'-cap of an RNA.
[ "GOC:sp", "PMID:25533955", "PMID:31101919" ]
null
[]
[]
[]
[]
[]
[ "GO:0016070" ]
[]
[]
[]
[ "GO:0016070" ]
[]
[]
[]
[]
[]
[]
kmv
2019-07-08T17:23:59Z
false
true
7
GO:0110155
110,155
NAD-cap decapping
biological_process
Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.
[ "GOC:sp", "PMID:25533955", "PMID:28283058", "PMID:31101919" ]
null
[]
[]
[]
[]
[]
[ "GO:0110154" ]
[]
[]
[]
[ "GO:0110154" ]
[]
[]
[]
[]
[]
[]
kmv
2019-07-08T17:27:56Z
false
true
2
GO:0110156
110,156
mRNA methylguanosine-cap decapping
biological_process
Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.
[ "PMID:23287066" ]
null
[]
[]
[]
[]
[]
[ "GO:0016071", "GO:0110154" ]
[]
[]
[]
[ "GO:0016071", "GO:0110154" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26915\" xsd:anyURI" ]
kmv
2019-07-08T17:31:07Z
false
true
1
GO:0110157
110,157
reelin complex
cellular_component
An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the em...
[ "GOC:bhm", "PMID:21844191", "PMID:28887403" ]
null
[]
[]
[]
[]
[]
[ "GO:0140392" ]
[]
[]
[]
[ "GO:0140392" ]
[]
[]
[]
[]
[]
[]
kmv
2019-07-15T15:10:58Z
false
true
7
GO:0110158
110,158
calpain complex
cellular_component
A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate.
[ "GOC:bhm", "PMID:10639123" ]
null
[ "M-calpain", "mu-calpain" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0008303" ]
[ "part_of GO:0005737" ]
[ "part_of" ]
[ "GO:0005737" ]
[ "GO:0005737", "GO:0008303" ]
[]
[]
[]
[]
[]
[]
kmv
2019-07-15T18:30:51Z
false
true
9
GO:0110159
110,159
regulation of mitotic spindle formation (spindle phase one)
biological_process
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).
[ "GOC:vw", "PMID:27697865" ]
null
[]
[]
[]
[]
[]
[ "GO:1901673" ]
[ "part_of GO:0032888", "regulates GO:0061804" ]
[ "part_of", "regulates" ]
[ "GO:0032888", "GO:0061804" ]
[ "GO:0032888", "GO:0061804", "GO:1901673" ]
[ "GO:0065007", "regulates GO:0061804" ]
[]
[]
[]
[]
[]
kmv
2019-08-12T15:10:26Z
false
true
6
GO:0110160
110,160
negative regulation of mitotic spindle formation (spindle phase one)
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).
[ "GOC:vw" ]
null
[]
[]
[]
[]
[]
[ "GO:0110159", "GO:1905831" ]
[ "negatively_regulates GO:0061804" ]
[ "negatively_regulates" ]
[ "GO:0061804" ]
[ "GO:0061804", "GO:0110159", "GO:1905831" ]
[ "GO:0065007", "negatively_regulates GO:0061804" ]
[]
[]
[]
[]
[]
kmv
2019-08-12T15:18:32Z
false
true
8
GO:0110162
110,162
regulation of mitotic spindle elongation (spindle phase three)
biological_process
Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
[ "GOC:vw", "PMID:27697865" ]
null
[]
[]
[]
[]
[]
[ "GO:0032888", "GO:0060236" ]
[ "regulates GO:0061805" ]
[ "regulates" ]
[ "GO:0061805" ]
[ "GO:0032888", "GO:0060236", "GO:0061805" ]
[ "GO:0065007", "regulates GO:0061805" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19745\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23317\" xsd:anyURI" ]
kmv
2019-08-12T15:26:01Z
false
true
8
GO:0110163
110,163
negative regulation of mitotic spindle elongation (spindle phase three)
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
[ "GOC:vw", "PMID:27697865" ]
null
[]
[]
[]
[]
[]
[ "GO:0051494", "GO:0110162", "GO:1902845" ]
[ "negatively_regulates GO:0061805" ]
[ "negatively_regulates" ]
[ "GO:0061805" ]
[ "GO:0051494", "GO:0061805", "GO:0110162", "GO:1902845" ]
[ "GO:0065007", "negatively_regulates GO:0061805" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23317\" xsd:anyURI" ]
kmv
2019-08-12T15:29:43Z
false
true
6
GO:0110164
110,164
positive regulation of mitotic spindle elongation (spindle phase three)
biological_process
Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
[ "GOC:vw", "PMID:27697865" ]
null
[]
[]
[]
[]
[]
[ "GO:0110028", "GO:0110162", "GO:1902846" ]
[ "positively_regulates GO:0061805" ]
[ "positively_regulates" ]
[ "GO:0061805" ]
[ "GO:0061805", "GO:0110028", "GO:0110162", "GO:1902846" ]
[ "GO:0065007", "positively_regulates GO:0061805" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23317\" xsd:anyURI" ]
kmv
2019-08-12T15:32:20Z
false
true
8
GO:0110165
110,165
cellular anatomical structure
cellular_component
A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
[ "GOC:kmv" ]
null
[ "cellular anatomical entity" ]
[ "EXACT" ]
[]
[ "gocheck_do_not_annotate", "goslim_pir" ]
[]
[ "GO:0005575" ]
[]
[]
[]
[ "GO:0005575" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24200\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26424\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28978\" xsd:anyURI" ]
kmv
2019-08-12T18:01:37Z
false
true
1
GO:0110166
110,166
DNA synthesis involved in mitochondrial DNA replication
biological_process
Any DNA biosynthetic process that is involved in mitochondrial DNA replication.
[ "PMID:28408491", "PMID:29931097" ]
null
[ "DNA biosynthetic process involved in mitochondrial DNA replication" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032042", "GO:0090592" ]
[ "part_of GO:0006264" ]
[ "part_of" ]
[ "GO:0006264" ]
[ "GO:0006264", "GO:0032042", "GO:0090592" ]
[ "GO:0071897", "part_of GO:0006264" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17716\" xsd:anyURI" ]
kmv
2020-03-18T13:30:39Z
false
true
1
GO:0120002
120,002
fusiform vesicle
cellular_component
A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder.
[ "GOC:krc", "PMID:21468280", "PMID:21887288" ]
null
[]
[]
[]
[]
[]
[ "GO:0031410" ]
[]
[]
[]
[ "GO:0031410" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12996\" xsd:anyURI" ]
krc
2017-02-23T21:12:27Z
false
true
3
GO:0120003
120,003
hinge region between urothelial plaques of apical plasma membrane
cellular_component
A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane.
[ "GOC:krc", "PMID:21468280", "PMID:21887288" ]
null
[]
[]
[]
[]
[]
[ "GO:0098590" ]
[ "part_of GO:0016324" ]
[ "part_of" ]
[ "GO:0016324" ]
[ "GO:0016324", "GO:0098590" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12996\" xsd:anyURI" ]
krc
2017-02-23T22:13:27Z
false
true
4
GO:0120006
120,006
regulation of glutamatergic neuron differentiation
biological_process
Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation.
[ "PMID:24030726" ]
null
[]
[]
[]
[]
[]
[ "GO:0045664" ]
[ "regulates GO:1905962" ]
[ "regulates" ]
[ "GO:1905962" ]
[ "GO:0045664", "GO:1905962" ]
[ "GO:0065007", "regulates GO:1905962" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13107\" xsd:anyURI" ]
krc
2017-03-01T16:10:27Z
false
true
2
GO:0120007
120,007
negative regulation of glutamatergic neuron differentiation
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.
[ "PMID:24030726" ]
null
[]
[]
[]
[]
[]
[ "GO:0045665", "GO:0120006" ]
[ "negatively_regulates GO:1905962" ]
[ "negatively_regulates" ]
[ "GO:1905962" ]
[ "GO:0045665", "GO:0120006", "GO:1905962" ]
[ "GO:0065007", "negatively_regulates GO:1905962" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13107\" xsd:anyURI" ]
krc
2017-03-01T16:25:50Z
false
true
2
GO:0120008
120,008
positive regulation of glutamatergic neuron differentiation
biological_process
Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.
[ "PMID:24030726" ]
null
[]
[]
[]
[]
[]
[ "GO:0045666", "GO:0120006" ]
[ "positively_regulates GO:1905962" ]
[ "positively_regulates" ]
[ "GO:1905962" ]
[ "GO:0045666", "GO:0120006", "GO:1905962" ]
[ "GO:0065007", "positively_regulates GO:1905962" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13107\" xsd:anyURI" ]
krc
2017-03-01T16:35:45Z
false
true
1
GO:0120009
120,009
intermembrane lipid transfer
biological_process
The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[]
[]
[]
[]
[]
[ "GO:0006869", "GO:0061024" ]
[]
[]
[]
[ "GO:0006869", "GO:0061024" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2017-03-16T20:30:42Z
false
true
5
GO:0120010
120,010
intermembrane phospholipid transfer
biological_process
The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[]
[]
[]
[]
[]
[ "GO:0015914", "GO:0120009" ]
[]
[]
[]
[ "GO:0015914", "GO:0120009" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2017-03-16T20:56:03Z
false
true
1
GO:0120011
120,011
intermembrane sterol transfer
biological_process
The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs...
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[]
[]
[]
[]
[]
[ "GO:0015918", "GO:0120009" ]
[]
[]
[]
[ "GO:0015918", "GO:0120009" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2017-03-16T22:15:40Z
false
true
3
GO:0120012
120,012
intermembrane sphingolipid transfer
biological_process
The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer pr...
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[]
[]
[]
[]
[]
[ "GO:0071705", "GO:0120009" ]
[]
[]
[]
[ "GO:0071705", "GO:0120009" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2017-03-16T22:20:45Z
false
true
1
GO:0120013
120,013
lipid transfer activity
molecular_function
Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[ "intermembrane lipid transfer activity", "lipid carrier activity" ]
[ "EXACT", "BROAD" ]
[]
[]
[ "Reactome:R-HSA-8856630 \"CIDEA:CIDEC binds lipid droplets\"", "Reactome:R-HSA-8858270 \"HILPDA binds lipid droplets\"", "Reactome:R-HSA-8862380 \"HSD17B13 binds lipid droplets\"", "Reactome:R-HSA-8874705 \"TTPA transports alpha-TOH from lysosomal membrane to plasma membrane\"", "Reactome:R-HSA-9856502 \"mi...
[ "GO:0005215", "GO:0005319" ]
[ "part_of GO:0120009" ]
[ "part_of" ]
[ "GO:0120009" ]
[ "GO:0005215", "GO:0005319", "GO:0120009" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17648\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31454\" xsd:anyURI" ]
krc
2017-03-17T03:17:29Z
false
true
7
GO:0120014
120,014
phospholipid transfer activity
molecular_function
Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[ "intermembrane phospholipid transfer activity", "phospholipid carrier activity" ]
[ "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0120013" ]
[ "has_part GO:0005543", "part_of GO:0015914" ]
[ "has_part", "part_of" ]
[ "GO:0005543", "GO:0015914" ]
[ "GO:0005543", "GO:0015914", "GO:0120013" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2017-03-17T03:34:17Z
false
true
6
GO:0120015
120,015
sterol transfer activity
molecular_function
Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[ "intermembrane sterol transfer activity", "sterol carrier activity" ]
[ "NARROW", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-5250531 \"ARV1 transports CHOL from ER membrane to plasma membrane\"", "Reactome:R-HSA-8867667 \"OSBPs transport 25OH-CHOL from ER membrane to plasma membrane\"", "Reactome:R-HSA-8868402 \"OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane\"" ]
[ "GO:0120013" ]
[ "has_part GO:0032934", "part_of GO:0015918" ]
[ "has_part", "part_of" ]
[ "GO:0032934", "GO:0015918" ]
[ "GO:0015918", "GO:0032934", "GO:0120013" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2017-03-17T03:46:28Z
false
true
6
GO:0120016
120,016
sphingolipid transfer activity
molecular_function
Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[ "intermembrane sphingolipid transfer activity", "sphingolipid carrier activity" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0120013" ]
[ "has_part GO:0046625" ]
[ "has_part" ]
[ "GO:0046625" ]
[ "GO:0046625", "GO:0120013" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2017-03-17T03:52:30Z
false
true
8
GO:0120017
120,017
ceramide transfer activity
molecular_function
Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[ "ceramide carrier activity", "ceramide transporter activity", "intermembrane ceramide transfer activity" ]
[ "EXACT", "BROAD", "NARROW" ]
[ "GO:0035620" ]
[]
[ "Reactome:R-HSA-9956909 \"CERT1-2 transfers CERA from the ER membrane to the Golgi membrane\"" ]
[ "GO:0120016" ]
[ "has_part GO:0097001" ]
[ "has_part" ]
[ "GO:0097001" ]
[ "GO:0097001", "GO:0120016" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2010-12-08T12:32:50Z
false
true
6
GO:0120021
120,021
oxysterol transfer activity
molecular_function
Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
[ "GOC:krc", "PMID:20823909", "PMID:24220498", "PMID:25797198" ]
null
[ "intermembrane oxysterol transfer activity", "oxysterol carrier activity" ]
[ "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0120015" ]
[ "has_part GO:0008142" ]
[ "has_part" ]
[ "GO:0008142" ]
[ "GO:0008142", "GO:0120015" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12329\" xsd:anyURI" ]
krc
2017-03-17T04:50:30Z
false
true
9
GO:0120022
120,022
glucagon family peptide binding
molecular_function
Binding to a member of the glucagon family peptide hormone (e.g. glucagon, glucagon-like peptides, oxyntomodulin, glicentin, ADCYAP1, GHRH, secretin, VIP, GIP).
[ "PMID:17715056" ]
null
[ "glucagon binding", "glucagon-like peptide binding" ]
[ "NARROW", "NARROW" ]
[ "GO:0120024" ]
[]
[]
[ "GO:0017046" ]
[]
[]
[]
[ "GO:0017046" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13143\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21327\" xsd:anyURI" ]
krc
2017-03-17T14:46:29Z
false
true
8
GO:0120023
120,023
somatostatin binding
molecular_function
Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatost...
[ "GOC:cvs", "PMID:20472043" ]
null
[]
[]
[]
[]
[]
[ "GO:0017046" ]
[]
[]
[]
[ "GO:0017046" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13143\" xsd:anyURI" ]
krc
2017-03-17T14:54:21Z
false
true
6
GO:0120025
120,025
plasma membrane bounded cell projection
cellular_component
A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0042995" ]
[ "has_part GO:0098590" ]
[ "has_part" ]
[ "GO:0098590" ]
[ "GO:0042995", "GO:0098590" ]
[ "GO:0042995", "has_part GO:0098590" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13193\" xsd:anyURI" ]
krc
2017-03-21T17:26:07Z
false
true
3
GO:0120026
120,026
host cell uropod
cellular_component
A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.
[ "PMID:24965475" ]
null
[ "host cell uropodium" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0044157" ]
[]
[]
[]
[ "GO:0044157" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13201\" xsd:anyURI" ]
krc
2017-03-22T21:33:31Z
false
true
5
GO:0120027
120,027
obsolete regulation of osmosensory signaling pathway
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of osmosensory signaling pathway.
[ "GOC:vw" ]
This term was obsoleted because it is an unnecessary grouping term.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13252\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26789\" xsd:anyURI" ]
krc
2017-03-31T14:45:01Z
true
true
2
GO:0120028
120,028
obsolete negative regulation of osmosensory signaling pathway
biological_process
OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway.
[ "GOC:vw" ]
This term was obsoleted because it is an unnecessary grouping term.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13252\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26789\" xsd:anyURI" ]
krc
2017-03-31T15:00:28Z
true
true
4
GO:0120029
120,029
proton export across plasma membrane
biological_process
The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region.
[ "GOC:mah", "PMID:9762918" ]
null
[ "hydrogen ion export across plasma membrane", "hydrogen ion export from cell", "proton export from cell" ]
[ "EXACT", "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0140115", "GO:1902600" ]
[]
[]
[]
[ "GO:0140115", "GO:1902600" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13271\" xsd:anyURI" ]
krc
2017-03-31T17:39:03Z
false
true
8
GO:0120030
120,030
positive regulation of cilium beat frequency involved in ciliary motility
biological_process
Any process that activates or increases the frequency of cilium beating involved in ciliary motility.
[ "PMID:28035044" ]
null
[]
[]
[]
[]
[]
[ "GO:0060296" ]
[]
[]
[]
[ "GO:0060296" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13375\" xsd:anyURI" ]
krc
2017-04-19T14:32:16Z
false
true
8
GO:0120031
120,031
plasma membrane bounded cell projection assembly
biological_process
Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
[ "GOC:krc" ]
null
[ "eupodium" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0030031", "GO:0120036" ]
[]
[]
[]
[ "GO:0030031", "GO:0120036" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13298\" xsd:anyURI" ]
krc
2017-04-24T23:56:08Z
false
true
4
GO:0120032
120,032
regulation of plasma membrane bounded cell projection assembly
biological_process
Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0060491", "GO:0120035" ]
[ "regulates GO:0120031" ]
[ "regulates" ]
[ "GO:0120031" ]
[ "GO:0060491", "GO:0120031", "GO:0120035" ]
[ "GO:0065007", "regulates GO:0120031" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13298\" xsd:anyURI" ]
krc
2017-04-26T04:27:04Z
false
true
3
GO:0120033
120,033
negative regulation of plasma membrane bounded cell projection assembly
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0031345", "GO:0120032" ]
[ "negatively_regulates GO:0120031" ]
[ "negatively_regulates" ]
[ "GO:0120031" ]
[ "GO:0031345", "GO:0120031", "GO:0120032" ]
[ "GO:0065007", "negatively_regulates GO:0120031" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13298\" xsd:anyURI" ]
krc
2017-04-26T04:34:31Z
false
true
7
GO:0120034
120,034
positive regulation of plasma membrane bounded cell projection assembly
biological_process
Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0031346", "GO:0044089", "GO:0120032" ]
[ "positively_regulates GO:0120031" ]
[ "positively_regulates" ]
[ "GO:0120031" ]
[ "GO:0031346", "GO:0044089", "GO:0120031", "GO:0120032" ]
[ "GO:0065007", "positively_regulates GO:0120031" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13298\" xsd:anyURI" ]
krc
2017-04-26T04:34:45Z
false
true
2
GO:0120035
120,035
regulation of plasma membrane bounded cell projection organization
biological_process
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0031344" ]
[ "regulates GO:0120036" ]
[ "regulates" ]
[ "GO:0120036" ]
[ "GO:0031344", "GO:0120036" ]
[ "GO:0065007", "regulates GO:0120036" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13298\" xsd:anyURI" ]
krc
2017-04-26T16:02:06Z
false
true
4
GO:0120036
120,036
plasma membrane bounded cell projection organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0030030" ]
[]
[]
[]
[ "GO:0030030" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13298\" xsd:anyURI" ]
krc
2017-04-26T16:07:02Z
false
true
4
GO:0120038
120,038
obsolete plasma membrane bounded cell projection part
cellular_component
OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0120025" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13298\" xsd:anyURI" ]
krc
2017-04-28T17:20:43Z
true
true
7
GO:0120039
120,039
plasma membrane bounded cell projection morphogenesis
biological_process
The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.
[ "GOC:krc" ]
null
[]
[]
[]
[]
[]
[ "GO:0048858" ]
[]
[]
[]
[ "GO:0048858" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13298\" xsd:anyURI" ]
krc
2017-04-28T23:39:37Z
false
true
9
GO:0120040
120,040
regulation of macrophage proliferation
biological_process
Any process that modulates the frequency, rate or extent of macrophage proliferation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph" ]
null
[]
[]
[]
[]
[]
[ "GO:0070663" ]
[ "regulates GO:0061517" ]
[ "regulates" ]
[ "GO:0061517" ]
[ "GO:0061517", "GO:0070663" ]
[ "GO:0065007", "regulates GO:0061517" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13470\" xsd:anyURI" ]
krc
2017-05-10T20:38:19Z
false
true
6
GO:0120041
120,041
positive regulation of macrophage proliferation
biological_process
Any process that activates or increases the frequency, rate or extent of macrophage proliferation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph" ]
null
[]
[]
[]
[]
[]
[ "GO:0070665", "GO:0120040" ]
[ "positively_regulates GO:0061517" ]
[ "positively_regulates" ]
[ "GO:0061517" ]
[ "GO:0061517", "GO:0070665", "GO:0120040" ]
[ "GO:0065007", "positively_regulates GO:0061517" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13470\" xsd:anyURI" ]
krc
2017-05-10T20:45:01Z
false
true
9
GO:0120042
120,042
negative regulation of macrophage proliferation
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation.
[ "GOC:BHF", "GOC:BHF_miRNA", "GOC:rph" ]
null
[]
[]
[]
[]
[]
[ "GO:0070664", "GO:0120040" ]
[ "negatively_regulates GO:0061517" ]
[ "negatively_regulates" ]
[ "GO:0061517" ]
[ "GO:0061517", "GO:0070664", "GO:0120040" ]
[ "GO:0065007", "negatively_regulates GO:0061517" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13470\" xsd:anyURI" ]
krc
2017-05-10T20:51:40Z
false
true
5