LiteFold/GO · Datasets at Hugging Face

GO:0150103

150,103

reactive gliosis

biological_process

A coordinated response of central nervous system (CNS) glial cells-including astrocytes, microglia, and NG2 glia-to injury, infection, or disease, characterized by changes in gene expression, morphology, proliferation, and extracellular matrix production. Reactive gliosis can range from transient glial activation to th...

[ "GOC:aruk", "GOC:bc", "PMID:20012068", "PMID:24267886", "PMID:24462092", "PMID:27049947" ]

null

[ "gliosis" ]

[ "BROAD" ]

[]

[ "GO:0150076" ]

[]

[ "GO:0150076" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30886\" xsd:anyURI" ]

bc

2019-05-21T12:37:31Z

false

true

1

GO:0150104

150,104

transport across blood-brain barrier

biological_process

The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.

[ "GOC:aruk", "GOC:bc", "PMID:29377008" ]

null

[ "transport across BBB", "transport across blood brain barrier" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0010232" ]

[]

[ "GO:0010232" ]

[]

bc

2019-05-27T09:12:03Z

false

true

9

GO:0150105

150,105

protein localization to cell-cell junction

biological_process

A process in which a protein is transported to, or maintained, in a location within a cell-cell junction.

[ "GOC:aruk", "GOC:bc", "PMID:26706435" ]

null

[]

[ "GO:1902414" ]

[]

[ "GO:1902414" ]

[]

bc

2019-06-11T11:00:18Z

false

true

6

GO:0150106

150,106

regulation of protein localization to cell-cell junction

biological_process

Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction.

[ "GOC:aruk", "GOC:bc", "PMID:26706435" ]

null

[]

[ "GO:0032880" ]

[ "regulates GO:0150105" ]

[ "regulates" ]

[ "GO:0150105" ]

[ "GO:0032880", "GO:0150105" ]

[ "GO:0065007", "regulates GO:0150105" ]

[]

bc

2019-06-11T11:17:15Z

false

true

9

GO:0150107

150,107

positive regulation of protein localization to cell-cell junction

biological_process

Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction.

[ "GOC:aruk", "GOC:bc", "PMID:26706435" ]

null

[]

[ "GO:0150106", "GO:1903829" ]

[ "positively_regulates GO:0150105" ]

[ "positively_regulates" ]

[ "GO:0150105" ]

[ "GO:0150105", "GO:0150106", "GO:1903829" ]

[ "GO:0065007", "positively_regulates GO:0150105" ]

[]

bc

2019-06-11T11:23:58Z

false

true

3

GO:0150110

150,110

obsolete negative regulation of cholesterol esterification

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol esterification.

[ "GOC:aruk", "GOC:bc", "PMID:21810484", "PMID:24201375" ]

This term was obsoleted because it represents a molecular function.

[]

[ "GO:0008203" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19255\" xsd:anyURI" ]

bc

2019-07-23T15:34:42Z

true

9

GO:0150111

150,111

regulation of transepithelial transport

biological_process

Any process that modulates the frequency, rate or extent of transepithelial transport.

[ "GOC:aruk", "PMID:27593915" ]

null

[]

[ "GO:0051049" ]

[ "regulates GO:0070633" ]

[ "regulates" ]

[ "GO:0070633" ]

[ "GO:0051049", "GO:0070633" ]

[ "GO:0065007", "regulates GO:0070633" ]

[]

bc

2019-09-15T07:16:49Z

false

true

1

GO:0150115

150,115

cell-substrate junction organization

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix.

[ "GOC:aruk", "GOC:bc", "PMID:10419689", "PMID:1643657", "PMID:16805308", "PMID:26923917", "PMID:8314002" ]

null

[]

[ "GO:0034330" ]

[]

[ "GO:0034330" ]

[]

bc

2019-11-14T11:06:29Z

false

true

5

GO:0150116

150,116

regulation of cell-substrate junction organization

biological_process

Any process that modulates the frequency, rate or extent of cell-substrate junction organization.

[ "GOC:aruk" ]

null

[]

[ "GO:0051128" ]

[ "regulates GO:0150115" ]

[ "regulates" ]

[ "GO:0150115" ]

[ "GO:0051128", "GO:0150115" ]

[ "GO:0065007", "regulates GO:0150115" ]

[]

bc

2019-11-14T12:12:27Z

false

true

4

GO:0150119

150,119

negative regulation of protein localization to cell-cell junction

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction.

[ "GOC:aruk", "GOC:bc" ]

null

[ "negative regulation of protein localisation to cell-cell junction" ]

[ "EXACT" ]

[]

[ "GO:0150106", "GO:1903828" ]

[ "negatively_regulates GO:0150105" ]

[ "negatively_regulates" ]

[ "GO:0150105" ]

[ "GO:0150105", "GO:0150106", "GO:1903828" ]

[ "GO:0065007", "negatively_regulates GO:0150105" ]

[]

bc

2019-11-21T13:53:34Z

false

true

6

GO:0150127

150,127

regulation of interleukin-33 production

biological_process

Any process that modulates the frequency, rate or extent of interleukin-33 production.

[ "GOC:aruk", "PMID:29778524" ]

null

[ "regulation of interleukin-33 biosynthetic process", "regulation of interleukin-33 secretion" ]

[ "NARROW", "NARROW" ]

[ "GO:0150123", "GO:0150130" ]

[]

[ "GO:0001817" ]

[ "regulates GO:0072639" ]

[ "regulates" ]

[ "GO:0072639" ]

[ "GO:0001817", "GO:0072639" ]

[ "GO:0065007", "regulates GO:0072639" ]

[]

bc

2019-12-03T05:54:03Z

false

true

8

GO:0150128

150,128

negative regulation of interleukin-33 production

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production.

[ "GOC:aruk", "PMID:29778524" ]

null

[ "negative regulation of interleukin-33 biosynthetic process", "negative regulation of interleukin-33 secretion" ]

[ "NARROW", "NARROW" ]

[ "GO:0150124", "GO:0150131" ]

[]

[ "GO:0001818", "GO:0150127" ]

[ "negatively_regulates GO:0072639" ]

[ "negatively_regulates" ]

[ "GO:0072639" ]

[ "GO:0001818", "GO:0072639", "GO:0150127" ]

[ "GO:0065007", "negatively_regulates GO:0072639" ]

[]

bc

2019-12-03T05:54:24Z

false

true

4

GO:0150129

150,129

positive regulation of interleukin-33 production

biological_process

Any process that activates or increases the frequency, rate or extent of interleukin-33 production.

[ "GOC:aruk" ]

null

[ "positive regulation of interleukin-33 biosynthetic process", "positive regulation of interleukin-33 secretion" ]

[ "NARROW", "NARROW" ]

[ "GO:0150125", "GO:0150132" ]

[]

[ "GO:0001819", "GO:0150127" ]

[ "positively_regulates GO:0072639" ]

[ "positively_regulates" ]

[ "GO:0072639" ]

[ "GO:0001819", "GO:0072639", "GO:0150127" ]

[ "GO:0065007", "positively_regulates GO:0072639" ]

[]

bc

2019-12-03T05:54:37Z

false

true

5

GO:0150138

150,138

negative regulation of interleukin-37 production

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production.

[ "GOC:aruk", "PMID:30362558" ]

null

[ "negative regulation of interleukin-37 biosynthetic process" ]

[ "NARROW" ]

[]

[ "GO:0001818", "GO:0150136" ]

[ "negatively_regulates GO:0150137" ]

[ "negatively_regulates" ]

[ "GO:0150137" ]

[ "GO:0001818", "GO:0150136", "GO:0150137" ]

[ "GO:0065007", "negatively_regulates GO:0150137" ]

[]

bc

2019-12-08T08:45:29Z

false

true

9

GO:0150139

150,139

positive regulation of interleukin-37 production

biological_process

Any process that activates or increases the frequency, rate or extent of interleukin-37 production.

[ "GOC:aruk" ]

null

[ "positive regulation of interleukin-37 biosynthetic process" ]

[ "NARROW" ]

[]

[ "GO:0001819", "GO:0150136" ]

[ "positively_regulates GO:0150137" ]

[ "positively_regulates" ]

[ "GO:0150137" ]

[ "GO:0001819", "GO:0150136", "GO:0150137" ]

[ "GO:0065007", "positively_regulates GO:0150137" ]

[]

bc

2019-12-08T08:47:29Z

false

true

4

GO:0150140

150,140

obsolete regulation of CD86 production

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of CD86 biosynthetic process.

[ "GOC:aruk", "PMID:26936882" ]

The reason for obsoletion is that this term represents a gene product.

[ "regulation of CD86 biosynthetic process" ]

[ "EXACT" ]

[]

[ "GO:0010559" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29735\" xsd:anyURI" ]

bc

2019-12-08T09:31:00Z

true

6

GO:0150141

150,141

obsolete negative regulation of CD86 production

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process.

[ "GOC:aruk", "PMID:26936882" ]

The reason for obsoletion is that this term represents a gene product.

[ "negative regulation of CD86 biosynthetic process" ]

[ "EXACT" ]

[]

[ "GO:0010561" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29735\" xsd:anyURI" ]

bc

2019-12-08T09:33:39Z

true

4

GO:0150142

150,142

obsolete positive regulation of CD86 production

biological_process

OBSOLETE. Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process.

[ "GOC:aruk" ]

The reason for obsoletion is that this term represents a gene product.

[ "positive regulation of CD86 biosynthetic process" ]

[ "EXACT" ]

[]

[ "GO:0010560" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29735\" xsd:anyURI" ]

bc

2019-12-08T09:35:35Z

true

8

GO:0150143

150,143

obsolete regulation of CD80 production

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of CD80 biosynthetic process.

[ "GOC:aruk", "PMID:26936882" ]

The reason for obsoletion is that this term represents a gene product.

[ "regulation of CD80 biosynthetic process" ]

[ "EXACT" ]

[]

[ "GO:0010559" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29735\" xsd:anyURI" ]

bc

2019-12-08T10:23:43Z

true

9

GO:0150144

150,144

obsolete negative regulation of CD80 production

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process.

[ "GOC:aruk", "PMID:26936882" ]

The reason for obsoletion is that this term represents a gene product.

[ "negative regulation of CD80 biosynthetic process" ]

[ "EXACT" ]

[]

[ "GO:0010561" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29735\" xsd:anyURI" ]

bc

2019-12-08T10:26:42Z

true

4

GO:0150145

150,145

obsolete positive regulation of CD80 production

biological_process

OBSOLETE. Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process.

[ "GOC:aruk" ]

The reason for obsoletion is that this term represents a gene product.

[ "positive regulation of CD80 biosynthetic process" ]

[ "EXACT" ]

[]

[ "GO:0010560" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29735\" xsd:anyURI" ]

bc

2019-12-08T10:29:00Z

true

7

GO:0150146

150,146

cell junction disassembly

biological_process

The disaggregation of a cell junction into its constituent components.

[ "GOC:aruk", "PMID:25490267" ]

null

[]

[ "GO:0022411", "GO:0034330" ]

[]

[ "GO:0022411", "GO:0034330" ]

[]

bc

2019-12-08T11:12:13Z

false

true

3

GO:0150147

150,147

cell-cell junction disassembly

biological_process

The disaggregation of a cell-cell junction into its constituent components.

[ "GOC:aruk", "PMID:25490267" ]

null

[]

[ "GO:0045216", "GO:0150146" ]

[]

[ "GO:0045216", "GO:0150146" ]

[]

bc

2019-12-08T11:16:14Z

false

true

6

GO:0150151

150,151

regulation of interleukin-17A production

biological_process

Any process that modulates the frequency, rate or extent of interleukin-17A production.

[ "GOC:aruk", "PMID:27901018" ]

null

[ "regulation of interleukin-17A biosynthetic process" ]

[ "NARROW" ]

[]

[ "GO:0032660" ]

[ "regulates GO:0097087" ]

[ "regulates" ]

[ "GO:0097087" ]

[ "GO:0032660", "GO:0097087" ]

[ "GO:0065007", "regulates GO:0097087" ]

[]

bc

2019-12-11T07:44:52Z

false

true

1

GO:0150152

150,152

negative regulation of interleukin-17A production

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production.

[ "GOC:aruk", "PMID:27901018" ]

null

[ "negative regulation of interleukin-17A biosynthetic process" ]

[ "NARROW" ]

[]

[ "GO:0032700", "GO:0150151" ]

[ "negatively_regulates GO:0097087" ]

[ "negatively_regulates" ]

[ "GO:0097087" ]

[ "GO:0032700", "GO:0097087", "GO:0150151" ]

[ "GO:0065007", "negatively_regulates GO:0097087" ]

[]

bc

2019-12-11T07:45:24Z

false

true

2

GO:0150153

150,153

positive regulation of interleukin-17A production

biological_process

Any process that activates or increases the frequency, rate or extent of interleukin-17A production.

[ "GOC:aruk" ]

null

[ "positive regulation of interleukin-17A biosynthetic process" ]

[ "NARROW" ]

[]

[ "GO:0032740", "GO:0150151" ]

[ "positively_regulates GO:0097087" ]

[ "positively_regulates" ]

[ "GO:0097087" ]

[ "GO:0032740", "GO:0097087", "GO:0150151" ]

[ "GO:0065007", "positively_regulates GO:0097087" ]

[]

bc

2019-12-11T07:45:44Z

false

true

7

GO:0150157

150,157

regulation of interleukin-34 production

biological_process

Any process that modulates the frequency, rate or extent of interleukin-34 production.

[ "GOC:aruk", "PMID:26754294" ]

null

[ "interleukin-34 biosynthetic process", "regulation of interleukin-34 biosynthetic process" ]

[ "NARROW", "NARROW" ]

[ "GO:0150156", "GO:0150160" ]

[]

[ "GO:0001817" ]

[ "regulates GO:0150155" ]

[ "regulates" ]

[ "GO:0150155" ]

[ "GO:0001817", "GO:0150155" ]

[ "GO:0065007", "regulates GO:0150155" ]

[]

bc

2020-01-06T16:30:44Z

false

true

5

GO:0150158

150,158

positive regulation of interleukin-34 production

biological_process

Any process that activates or increases the frequency, rate or extent of interleukin-34 production.

[ "GOC:aruk" ]

null

[ "positive regulation of interleukin-34 biosynthetic process" ]

[ "NARROW" ]

[ "GO:0150161" ]

[]

[ "GO:0001819", "GO:0150157" ]

[ "positively_regulates GO:0150155" ]

[ "positively_regulates" ]

[ "GO:0150155" ]

[ "GO:0001819", "GO:0150155", "GO:0150157" ]

[ "GO:0065007", "positively_regulates GO:0150155" ]

[]

bc

2020-01-06T16:31:00Z

false

true

3

GO:0150159

150,159

negative regulation of interleukin-34 production

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production.

[ "GOC:aruk", "PMID:26754294" ]

null

[ "negative regulation of interleukin-34 biosynthetic process" ]

[ "NARROW" ]

[ "GO:0150162" ]

[]

[ "GO:0001818", "GO:0150157" ]

[ "negatively_regulates GO:0150155" ]

[ "negatively_regulates" ]

[ "GO:0150155" ]

[ "GO:0001818", "GO:0150155", "GO:0150157" ]

[ "GO:0065007", "negatively_regulates GO:0150155" ]

[]

bc

2020-01-06T16:31:12Z

false

true

2

GO:0150163

150,163

obsolete miRNA-mediated activation of transcription by RNA polymerase II

biological_process

OBSOLETE. Any process mediated by a microRNA (miRNA) that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

[ "GOC:aruk", "PMID:20737563", "PMID:27145859" ]

This term was obsoleted because there is no evidence that this process exists.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18512\" xsd:anyURI" ]

bc

2020-01-14T12:08:14Z

true

7

GO:0150164

150,164

obsolete miRNA-mediated regulation of transcription by RNA polymerase II

biological_process

OBSOLETE. Any process mediated by a microRNA (miRNA) that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.

[ "GOC:aruk", "PMID:20737563", "PMID:27145859" ]

This term was obsoleted because there is no evidence that this process exists.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18512\" xsd:anyURI" ]

bc

2020-01-14T12:16:32Z

true

4

GO:0150165

150,165

obsolete miRNA-mediated inhibition of transcription by RNA polymerase II

biological_process

OBSOLETE. Any process mediated by a microRNA (miRNA) that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.

[ "GOC:aruk" ]

This term was obsoleted because there is no evidence that this process exists.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18512\" xsd:anyURI" ]

bc

2020-01-14T12:21:12Z

true

7

GO:0150166

150,166

obsolete regulation of histone H3-K4 acetylation

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of histone H3-K4 acetylation.

[ "GOC:aruk" ]

This term was obsoleted because it represents a molecular function.

[]

[ "GO:0044016" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

bc

2020-01-14T12:27:26Z

true

3

GO:0150168

150,168

obsolete negative regulation of histone H3-K4 acetylation

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 acetylation.

[ "GOC:aruk" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

bc

2020-01-14T12:34:01Z

true

4

GO:0150172

150,172

regulation of phosphatidylcholine metabolic process

biological_process

Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process.

[ "GOC:aruk", "GOC:bc", "PMID:30074985" ]

null

[]

[ "GO:1903725" ]

[ "regulates GO:0046470" ]

[ "regulates" ]

[ "GO:0046470" ]

[ "GO:0046470", "GO:1903725" ]

[ "GO:0065007", "regulates GO:0046470" ]

[]

bc

2020-01-21T14:03:11Z

false

true

9

GO:0150174

150,174

obsolete negative regulation of phosphatidylcholine metabolic process

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process.

[ "GOC:aruk", "GOC:bc", "PMID:30074985" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30570\" xsd:anyURI" ]

bc

2020-01-21T14:03:53Z

true

5

GO:0150175

150,175

regulation of phosphatidylethanolamine metabolic process

biological_process

Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process.

[ "GOC:aruk", "GOC:bc", "PMID:30074985" ]

null

[]

[ "GO:1903725" ]

[ "regulates GO:0046337" ]

[ "regulates" ]

[ "GO:0046337" ]

[ "GO:0046337", "GO:1903725" ]

[ "GO:0065007", "regulates GO:0046337" ]

[]

bc

2020-01-21T14:04:12Z

false

true

1

GO:0150176

150,176

obsolete positive regulation of phosphatidylethanolamine metabolic process

biological_process

OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process.

[ "GOC:aruk", "GOC:bc", "PMID:30074985" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30570\" xsd:anyURI" ]

bc

2020-01-21T14:04:32Z

true

1

GO:0150177

150,177

obsolete negative regulation of phosphatidylethanolamine metabolic process

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process.

[ "GOC:aruk", "GOC:bc", "PMID:30074985" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30570\" xsd:anyURI" ]

bc

2020-01-21T14:05:00Z

true

8

GO:0150178

150,178

obsolete regulation of phosphatidylserine metabolic process

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process.

[ "GOC:aruk", "GOC:bc", "PMID:30074985" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30570\" xsd:anyURI" ]

bc

2020-01-21T14:05:21Z

true

1

GO:0150179

150,179

obsolete positive regulation of phosphatidylserine metabolic process

biological_process

OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process.

[ "GOC:aruk", "GOC:bc", "PMID:30074985" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30570\" xsd:anyURI" ]

bc

2020-01-21T14:05:52Z

true

7

GO:0150180

150,180

obsolete negative regulation of phosphatidylserine metabolic process

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process.

[ "GOC:aruk", "GOC:bc", "PMID:30074985" ]

This term was obsoleted because it is an unnecessary grouping class.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30570\" xsd:anyURI" ]

bc

2020-01-21T14:06:06Z

true

8

GO:0150189

150,189

regulation of interleukin-32 production

biological_process

Any process that modulates the frequency, rate or extent of interleukin-32 production.

[ "GOC:aruk", "PMID:23729669" ]

null

[ "regulation of interleukin-32 biosynthetic process", "regulation of interleukin-32 secretion" ]

[ "NARROW", "NARROW" ]

[ "GO:0150192" ]

[]

[ "GO:0001817" ]

[ "regulates GO:0072637" ]

[ "regulates" ]

[ "GO:0072637" ]

[ "GO:0001817", "GO:0072637" ]

[ "GO:0065007", "regulates GO:0072637" ]

[]

bc

2020-02-21T10:28:36Z

false

true

3

GO:0150190

150,190

negative regulation of interleukin-32 production

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production.

[ "GOC:aruk", "PMID:23729669" ]

null

[ "negative regulation of interleukin-32 biosynthetic process", "negative regulation of interleukin-32 secretion" ]

[ "NARROW", "NARROW" ]

[ "GO:0150193" ]

[]

[ "GO:0001818", "GO:0150189" ]

[ "negatively_regulates GO:0072637" ]

[ "negatively_regulates" ]

[ "GO:0072637" ]

[ "GO:0001818", "GO:0072637", "GO:0150189" ]

[ "GO:0065007", "negatively_regulates GO:0072637" ]

[]

bc

2020-02-21T10:31:53Z

false

true

3

GO:0150191

150,191

positive regulation of interleukin-32 production

biological_process

Any process that activates or increases the frequency, rate or extent of interleukin-32 production.

[ "GOC:aruk" ]

null

[ "positive regulation of interleukin-32 biosynthetic process", "positive regulation of interleukin-32 secretion" ]

[ "NARROW", "NARROW" ]

[ "GO:0150194" ]

[]

[ "GO:0001819", "GO:0150189" ]

[ "positively_regulates GO:0072637" ]

[ "positively_regulates" ]

[ "GO:0072637" ]

[ "GO:0001819", "GO:0072637", "GO:0150189" ]

[ "GO:0065007", "positively_regulates GO:0072637" ]

[]

bc

2020-02-21T10:33:39Z

false

true

3

GO:0150195

150,195

transport across blood-cerebrospinal fluid barrier

biological_process

The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier.

[ "GOC:aruk", "GOC:bc", "PMID:21349151" ]

null

[ "transport across BCSFB", "transport across blood-CSF barrier", "transport across blood/cerebrospinal fluid barrier", "transport across blood/CSF barrier" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0010232" ]

[]

[ "GO:0010232" ]

[]

bc

2020-03-26T14:43:04Z

false

true

8

GO:0150200

150,200

regulation of transport across blood-brain barrier

biological_process

Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier.

[ "GOC:aruk", "GOC:bc", "PMID:29377008", "PMID:30280653" ]

null

[]

[ "GO:0044057", "GO:0051049" ]

[ "part_of GO:0043114", "regulates GO:0150104" ]

[ "part_of", "regulates" ]

[ "GO:0043114", "GO:0150104" ]

[ "GO:0043114", "GO:0044057", "GO:0051049", "GO:0150104" ]

[ "GO:0065007", "regulates GO:0150104" ]

[]

bc

2020-03-26T19:22:26Z

false

true

9

GO:0150201

150,201

positive regulation of transport across blood-brain barrier

biological_process

Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier.

[ "GOC:aruk", "GOC:bc", "PMID:29377008", "PMID:30280653" ]

null

[]

[ "GO:0051050", "GO:0051240", "GO:0150200" ]

[ "part_of GO:0043117", "positively_regulates GO:0150104" ]

[ "part_of", "positively_regulates" ]

[ "GO:0043117", "GO:0150104" ]

[ "GO:0043117", "GO:0051050", "GO:0051240", "GO:0150104", "GO:0150200" ]

[ "GO:0065007", "positively_regulates GO:0150104" ]

[]

bc

2020-03-26T19:26:38Z

false

true

8

GO:0150202

150,202

negative regulation of transport across blood-brain barrier

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier.

[ "GOC:aruk", "GOC:bc", "PMID:29377008", "PMID:30280653" ]

null

[]

[ "GO:0051051", "GO:0051241", "GO:0150200" ]

[ "negatively_regulates GO:0150104", "part_of GO:0043116" ]

[ "negatively_regulates", "part_of" ]

[ "GO:0150104", "GO:0043116" ]

[ "GO:0043116", "GO:0051051", "GO:0051241", "GO:0150104", "GO:0150200" ]

[ "GO:0065007", "negatively_regulates GO:0150104" ]

[]

bc

2020-03-26T19:28:51Z

false

true

4

GO:0151001

151,001

tuft

cellular_component

A dense cluster of elongated, thick microvilli on the apical surface of tuft cells in epithelial tissues, such as the intestine and respiratory tract. The apical tuft extends further into the lumen than typical microvilli, featuring larger, more compact projections with unique actin cores that penetrate deep into the c...

[ "PMID:15817800", "PMID:35237268" ]

null

[]

[ "GO:0098862" ]

[ "has_part GO:0005902" ]

[ "has_part" ]

[ "GO:0005902" ]

[ "GO:0005902", "GO:0098862" ]

[]

ce

2024-11-14T11:13:07Z

false

true

7

GO:0160001

160,001

extrasynaptic signaling via GABA

biological_process

Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid.

[ "PMID:23038269", "PMID:9364051" ]

null

[]

[ "GO:0007214" ]

[]

[ "GO:0007214" ]

[]

rl

2021-02-26T23:08:15Z

false

true

5

GO:0160002

160,002

ADP-D-ribose modification-dependent protein binding

molecular_function

Binding to a protein upon ADP-ribosylation of the target protein.

[ "PMID:26673700" ]

This term should only be used when the binding is shown to require a ADP-D-ribose post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the ADP-D-ribose modification. It may be that the PTM causes a conformational change that allows ...

[]

[ "GO:0140030" ]

[]

[ "GO:0140030" ]

[]

rl

2021-07-12T23:31:53Z

false

true

5

GO:0160003

160,003

mono-ADP-D-ribose modification-dependent protein binding

molecular_function

Binding to a protein upon mono-ADP-ribosylation of the target protein.

[ "PMID:34023495" ]

This term should only be used when the binding is shown to require a mono-ADP-D-ribose post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the ADP-D-ribose modification. It may be that the PTM causes a conformational change that al...

[]

[ "GO:0160002" ]

[]

[ "GO:0160002" ]

[]

[ "GO:0160004" ]

[]

rl

2021-07-12T23:36:00Z

false

true

8

GO:0160005

160,005

PAT complex

cellular_component

A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the correct folding of multipass membrane proteins in the ER membrane. In human, the substrate-binding Asterix (PAT10, WDR83OS) forms an obligate heterodimer with CCDC47.

[ "PMID:32814900", "PMID:33082068", "PMID:33960686" ]

PAT complex functions by shielding exposed hydrophilicity of transmembrane domains (TMDs) to prevent premature degradation and promote proper folding and bundling of TMDs.

[]

[ "GO:0098796", "GO:0140534" ]

[ "part_of GO:0005789" ]

[ "part_of" ]

[ "GO:0005789" ]

[ "GO:0005789", "GO:0098796", "GO:0140534" ]

[]

rynl

2021-09-03T23:12:58Z

false

true

7

GO:0160006

160,006

Fc receptor-mediated immune complex endocytosis

biological_process

An endocytosis process mediated by the Fc receptor for the purpose of delivery of antigen-bound immunoglobulin to an intracellular compartment where the antigen can be processed and loaded onto MHC molecules. This process selectively targets antigens for presentation by MHC class II or cross-presentation by MHC class I...

[ "PMID:28389502", "PMID:9143687", "PMID:9463401" ]

null

[ "antigen-antibody immune complex uptake via Fc receptor", "Fc receptor-mediated immune complex internalization", "Ig-complexed antigen endocytosis via Fc receptor" ]

[ "EXACT", "RELATED", "EXACT" ]

[]

[ "GO:0006898" ]

[]

[ "GO:0006898" ]

[]

rynl

2021-11-05T23:38:29Z

false

true

8

GO:0160007

160,007

glutathione import into mitochondrion

biological_process

The process in which glutathione is transported from the cytosol into the mitochondrial matrix.

[ "PMID:34707288" ]

null

[]

[ "GO:0010496", "GO:0034775" ]

[]

[ "GO:0010496", "GO:0034775" ]

[]

rynl

2021-11-11T22:53:16Z

false

true

6

GO:0160008

160,008

protein decrotonylase activity

molecular_function

Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] = (2E)-2-butenoate + L-lysyl-[protein].

[ "PMID:28497810", "PMID:30279482", "PMID:34608293" ]

null

[]

[ "RHEA:69172" ]

[ "GO:0016811" ]

[]

[ "GO:0016811" ]

[]

[ "skos:exactMatch RHEA:69172", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

rynl

2021-11-16T00:55:21Z

false

true

3

GO:0160009

160,009

histone decrotonylase activity

molecular_function

Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone] = (2E)-2-butenoate + L-lysyl-[histone].

[ "PMID:28497810" ]

null

[]

[ "GO:0140993", "GO:0160008" ]

[]

[ "GO:0140993", "GO:0160008" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22351\" xsd:anyURI" ]

rynl

2021-11-16T01:08:57Z

false

true

9

GO:0160010

160,010

protein de-2-hydroxyisobutyrylase activity

molecular_function

Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein].

[ "PMID:29192674" ]

null

[]

[ "RHEA:69176" ]

[ "GO:0016811" ]

[]

[ "GO:0016811" ]

[]

[ "skos:exactMatch RHEA:69176", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

rynl

2021-11-16T01:15:34Z

false

true

8

GO:0160011

160,011

NAD-dependent protein decrotonylase activity

molecular_function

Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.

[ "PMID:28497810" ]

null

[]

[ "RHEA:69332" ]

[ "GO:0016747" ]

[]

[ "GO:0016747" ]

[]

[ "skos:exactMatch RHEA:69332", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

rynl

2021-11-16T01:22:43Z

false

true

5

GO:0160012

160,012

histone decrotonylase activity, NAD-dependent

molecular_function

Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone] + nicotinamide.

[ "PMID:28497810" ]

null

[ "NAD-dependent histone decrotonylase activity" ]

[ "EXACT" ]

[]

[ "GO:0160009", "GO:0160011" ]

[]

[ "GO:0160009", "GO:0160011" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22351\" xsd:anyURI" ]

rynl

2021-11-16T01:25:28Z

false

true

6

GO:0160013

160,013

NAD-dependent protein de-2-hydroxyisobutyrylase activity

molecular_function

Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD+ = 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.

[ "PMID:31328167" ]

null

[]

[ "RHEA:24364" ]

[ "GO:0016747" ]

[]

[ "GO:0016747" ]

[]

[ "skos:exactMatch RHEA:24364", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

rynl

2021-11-16T01:28:33Z

false

true

2

GO:0160014

160,014

exopher

cellular_component

An extracellular vesicle that is approximately four microns in diameter, released by budding out of cells into the extracellular space, and hypothesized to be a mechanism for disposal of unwanted cellular material including protein aggregates and damaged organelles.

[ "PMID:28178240", "PMID:33016946", "PMID:33027673", "PMID:33659873", "PMID:34288362", "PMID:34475208" ]

null

[]

[ "GO:1903561" ]

[]

[ "GO:1903561" ]

[]

rynl

2021-12-13T21:57:12Z

false

true

2

GO:0160015

160,015

platelet rolling

biological_process

Transient adhesive interactions between platelets and endothelial cells lining blood vessels. Carbohydrates on circulating platelets bind selectins or other molecules on the vessel wall causing the platelets to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds a...

[ "GOC:sl", "PMID:29018081" ]

null

[]

[ "GO:0034113" ]

[]

[ "GO:0034113" ]

[]

rynl

2021-12-15T17:36:55Z

false

true

8

GO:0160016

160,016

CCACCA tRNA nucleotidyltransferase activity

molecular_function

Catalysis of the reaction: a tRNA with a 3' CCA end + 2 CTP + ATP = a tRNA with a 3' CCACCA end + 3 diphosphate.

[ "PMID:22076379", "RHEA:76235" ]

null

[]

[ "RHEA:76235" ]

[ "GO:0070567", "GO:0140101" ]

[]

[ "GO:0070567", "GO:0140101" ]

[]

[ "skos:exactMatch RHEA:76235", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25021\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

rynl

2023-02-28T20:51:52Z

false

true

1

GO:0160017

160,017

regulation of platelet rolling

biological_process

Any process that modulates the frequency, rate or extent of platelet rolling.

[ "GO_REF:0000058", "GOC:sl" ]

null

[]

[ "GO:0034114" ]

[ "regulates GO:0160015" ]

[ "regulates" ]

[ "GO:0160015" ]

[ "GO:0034114", "GO:0160015" ]

[ "GO:0065007", "regulates GO:0160015" ]

[]

rynl

2021-12-17T23:21:27Z

false

true

5

GO:0160018

160,018

positive regulation of platelet rolling

biological_process

Any process that increases the rate, frequency, or extent of platelet rolling.

[ "GO_REF:0000058", "GOC:sl" ]

null

[]

[ "GO:0034116", "GO:0160017" ]

[ "positively_regulates GO:0160015" ]

[ "positively_regulates" ]

[ "GO:0160015" ]

[ "GO:0034116", "GO:0160015", "GO:0160017" ]

[ "GO:0065007", "positively_regulates GO:0160015" ]

[]

rynl

2021-12-17T23:42:57Z

false

true

2

GO:0160019

160,019

negative regulation of platelet rolling

biological_process

Any process that decreases the rate, frequency, or extent of platelet rolling.

[ "GO_REF:0000058", "GOC:sl", "PMID:15738422" ]

null

[]

[ "GO:0034115", "GO:0160017" ]

[ "negatively_regulates GO:0160015" ]

[ "negatively_regulates" ]

[ "GO:0160015" ]

[ "GO:0034115", "GO:0160015", "GO:0160017" ]

[ "GO:0065007", "negatively_regulates GO:0160015" ]

[]

rynl

2021-12-17T23:50:57Z

false

true

7

GO:0160020

160,020

positive regulation of ferroptosis

biological_process

Any process that activates or increases the frequency, rate or extent of ferroptosis.

[ "PMID:32015325" ]

null

[]

[ "GO:0043068", "GO:0110075" ]

[ "positively_regulates GO:0097707" ]

[ "positively_regulates" ]

[ "GO:0097707" ]

[ "GO:0043068", "GO:0097707", "GO:0110075" ]

[ "GO:0065007", "positively_regulates GO:0097707" ]

[]

rynl

2022-01-19T17:39:58Z

false

true

2

GO:0160021

160,021

maternal-to-zygotic transition of gene expression

biological_process

Any process that modulates the frequency, rate or extent of gene expression by which developmental control passes from the maternal genome to the zygotic genome.

[ "PMID:19204068", "PMID:32558204" ]

null

[ "MZT" ]

[ "RELATED" ]

[]

[ "Reactome:R-HSA-9816359 \"Maternal to zygotic transition (MZT)\"" ]

[ "GO:0010468" ]

[]

[ "GO:0010468" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22659\" xsd:anyURI" ]

rynl

2022-01-19T18:55:21Z

false

true

5

GO:0160022

160,022

apocrine secretion

biological_process

The controlled release of a substance by a cell or a tissue by discharging a portion of the secreting cell when intracellular components are freed into a lumen through the shedding of whole pieces of the cytoplasm.

[ "PMID:25960390" ]

null

[ "secretion by cell decapitation", "secretion by membrane budding" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0046903" ]

[]

[ "GO:0046903" ]

[]

rynl

2022-01-21T01:28:58Z

false

true

3

GO:0160023

160,023

sneeze reflex

biological_process

A reflex process that expels air forcibly from the mouth and nose in an explosive, spasmodic involuntary action resulting chiefly from irritation of the nasal mucous membrane.

[ "https://www.thefreedictionary.com/sneeze", "PMID:34133943" ]

null

[ "sternutation" ]

[ "EXACT" ]

[]

[ "GO:0060004" ]

[]

[ "GO:0060004" ]

[]

rynl

2022-02-07T16:50:31Z

false

true

1

GO:0160024

160,024

Leydig cell proliferation

biological_process

The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone.

[ "PMID:29632025" ]

null

[]

[ "GO:0008283" ]

[]

[ "GO:0008283" ]

[]

rynl

2022-02-08T20:09:53Z

false

true

9

GO:0160025

160,025

sensory perception of itch

biological_process

A sensory perception which causes the desire or reflex to scratch.

[ "PMID:26015312", "PMID:29723501", "PMID:30734045", "Wikipedia:Itch" ]

null

[ "pruritus" ]

[ "EXACT" ]

[]

[ "GO:0007600" ]

[]

[ "GO:0007600" ]

[]

rynl

2022-02-09T23:50:34Z

false

true

4

GO:0160027

160,027

egg deposition

biological_process

The multicellular organismal reproductive process that results in the movement of an egg from within an organism into the external environment.

[ "PMID:18050396", "PMID:31164023" ]

null

[]

[ "GO:0048609" ]

[]

[ "GO:0048609" ]

[]

rynl

2023-03-01T18:56:53Z

false

true

3

GO:0160028

160,028

negative regulation of pyroptotic inflammatory response

biological_process

Any process that decreases the frequency, rate or extent of a pyroptotic inflammatory response.

[ "PMID:34637033" ]

null

[ "negative regulation of pyroptosis" ]

[ "BROAD" ]

[]

[ "GO:0050728" ]

[ "negatively_regulates GO:0070269" ]

[ "negatively_regulates" ]

[ "GO:0070269" ]

[ "GO:0050728", "GO:0070269" ]

[ "GO:0065007", "negatively_regulates GO:0070269" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21399\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27753\" xsd:anyURI" ]

rynl

2022-03-16T23:07:16Z

false

true

2

GO:0160029

160,029

kidney cortex tubule cell dedifferentiation

biological_process

The process in which a kidney cortex tubule cell (specialized epithelial cell of the kidney) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the feature...

[ "PMID:18987110", "PMID:31847447" ]

Following injury, renal cortex tubular epithelial cell appears to be undergoing epithelial-mesenchymal transition, detected by overexpression of vimentin. {xref="PMID:31847447"}

[]

[ "GO:0043697" ]

[]

[ "GO:0043697" ]

[]

rynl

2022-04-11T20:51:10Z

false

true

8

GO:0160030

160,030

pollen intine formation

biological_process

Formation of pollen intine, the inner layer of the pollen wall. The reticulate pollen wall pattern consists of two layers, exine and intine.

[ "PMID:35498668" ]

null

[]

[ "GO:0010208" ]

[]

[ "GO:0010208" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23330\" xsd:anyURI" ]

rynl

2022-05-17T18:13:46Z

false

true

4

GO:0160031

160,031

endoplasmic reticulum membrane biogenesis

biological_process

The process in which an endoplasmic reticulum membrane is synthesized, aggregates, and bonds together.

[ "PMID:19825355", "PMID:24373967", "PMID:34617598" ]

null

[ "ER membrane biogenesis" ]

[ "EXACT" ]

[]

[ "GO:0044091" ]

[ "part_of GO:0090158" ]

[ "part_of" ]

[ "GO:0090158" ]

[ "GO:0044091", "GO:0090158" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22720\" xsd:anyURI" ]

rynl

2022-06-06T22:31:36Z

false

true

3

GO:0160032

160,032

Toll receptor ligand protein activation cascade

biological_process

A protein activation cascade that generates the active Toll receptor ligand and consists of the cascade of enzymatic reactions initiated by extracellular recognition factors, leading to the cleavage of the inactive form of spatzle family of ligands.

[ "PMID:23632253" ]

This term specifically mentions the Toll receptor and its ligand spatzle because this is the only known example of such an activation cascade for a ligand.

[]

[ "GO:0072376" ]

[ "has_part GO:0140448" ]

[ "has_part" ]

[ "GO:0140448" ]

[ "GO:0072376", "GO:0140448" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23378\" xsd:anyURI" ]

rynl

2022-06-07T23:48:31Z

false

true

7

GO:0160033

160,033

regulation of Toll receptor ligand protein activation cascade

biological_process

Any process that modulates the frequency, rate or extent of the Toll receptor ligand protein activation cascade.

[ "PMID:23632253" ]

null

[]

[ "GO:2000257" ]

[ "regulates GO:0160032" ]

[ "regulates" ]

[ "GO:0160032" ]

[ "GO:0160032", "GO:2000257" ]

[ "GO:0065007", "regulates GO:0160032" ]

[]

rynl

2022-06-28T16:08:31Z

false

true

7

GO:0160034

160,034

positive regulation of Toll receptor ligand protein activation cascade

biological_process

Any process that activates or increases the frequency, rate or extent of Toll receptor ligand protein activation cascade.

[ "PMID:23632253" ]

null

[]

[ "GO:0160033", "GO:2000259" ]

[ "positively_regulates GO:0160032" ]

[ "positively_regulates" ]

[ "GO:0160032" ]

[ "GO:0160032", "GO:0160033", "GO:2000259" ]

[ "GO:0065007", "positively_regulates GO:0160032" ]

[]

rynl

2022-06-28T16:45:30Z

false

true

3

GO:0160035

160,035

negative regulation of Toll receptor ligand protein activation cascade

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of Toll receptor ligand protein activation cascade.

[ "PMID:23632253" ]

null

[]

[ "GO:0160033", "GO:2000258" ]

[ "negatively_regulates GO:0160032" ]

[ "negatively_regulates" ]

[ "GO:0160032" ]

[ "GO:0160032", "GO:0160033", "GO:2000258" ]

[ "GO:0065007", "negatively_regulates GO:0160032" ]

[]

rynl

2022-06-28T16:46:24Z

false

true

3

GO:0160036

160,036

positive regulation of postsynaptic density assembly

biological_process

Any process that activates or increases the frequency, rate or extent of postsynaptic density assembly.

[ "PMID:17626212" ]

null

[]

[ "GO:0099151", "GO:1902117", "GO:1905876" ]

[ "positively_regulates GO:0097107" ]

[ "positively_regulates" ]

[ "GO:0097107" ]

[ "GO:0097107", "GO:0099151", "GO:1902117", "GO:1905876" ]

[ "GO:0065007", "positively_regulates GO:0097107" ]

[]

rynl

2022-06-29T16:14:49Z

false

true

6

GO:0160037

160,037

negative regulation of postsynaptic density assembly

biological_process

Any process that decreases the rate, frequency, or extent of postsynaptic density assembly.

[ "PMID:17626212" ]

null

[]

[ "GO:0099151", "GO:1902116", "GO:1905875" ]

[ "negatively_regulates GO:0097107" ]

[ "negatively_regulates" ]

[ "GO:0097107" ]

[ "GO:0097107", "GO:0099151", "GO:1902116", "GO:1905875" ]

[ "GO:0065007", "negatively_regulates GO:0097107" ]

[]

rynl

2022-06-29T16:15:24Z

false

true

5

GO:0160038

160,038

somatic sensory system development

biological_process

The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain.

[ "PMID:25832476", "PMID:31399790" ]

null

[ "somatosensory system development" ]

[ "EXACT" ]

[]

[ "GO:0048880" ]

[]

[ "GO:0048880" ]

[]

rynl

2022-07-07T16:49:26Z

false

true

3

GO:0160039

160,039

serotonin-gated chloride channel activity

molecular_function

Enables the transmembrane transfer of a chloride ion by a channel that opens when the biogenic amine serotonin has been bound by the channel complex or one of its constituent parts. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.

[ "PMID:11100728" ]

null

[]

[ "TC:1.A.9", "Wikipedia:Ligand-gated_ion_channel" ]

[ "GO:0005254", "GO:0022824", "GO:0099095", "GO:0099589" ]

[ "part_of GO:0007210" ]

[ "part_of" ]

[ "GO:0007210" ]

[ "GO:0005254", "GO:0007210", "GO:0022824", "GO:0099095", "GO:0099589" ]

[]

rynl

2022-07-12T18:19:13Z

false

true

3

GO:0160040

160,040

mitocytosis

biological_process

A migrasome-mediated selective removal of damaged mitochondria process that maintains mitochondrion homeostasis in migrating cells.

[ "PMID:34108688" ]

null

[]

[ "GO:0048311", "GO:0051654", "GO:0140495" ]

[]

[ "GO:0048311", "GO:0051654", "GO:0140495" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23807\" xsd:anyURI" ]

rynl

2022-08-16T15:59:35Z

false

true

1

GO:0160041

160,041

neuropeptide activity

molecular_function

The receptor ligand activity of any polypeptide expressed in, and secreted from a neuron.

[ "PMID:18806786", "PMID:21922398" ]

null

[]

[ "GO:0048018" ]

[ "has_part GO:0071855" ]

[ "has_part" ]

[ "GO:0071855" ]

[ "GO:0048018", "GO:0071855" ]

[]

rynl

2023-03-10T01:05:22Z

false

true

4

GO:0160042

160,042

purine nucleotide uniporter activity

molecular_function

Catalysis of the active transport of purine nucleotides across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.

[ "PMID:18375752", "PMID:27477609" ]

null

[]

[ "GO:0015216", "GO:0022810" ]

[]

[ "GO:0015216", "GO:0022810" ]

[]

rynl

2023-03-11T00:58:42Z

false

true

2

GO:0160043

160,043

catecholamine secretion, neurotransmission

biological_process

The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter.

[ "PMID:10191060" ]

null

[]

[ "GO:0007269", "GO:0050432" ]

[]

[ "GO:0007269", "GO:0050432" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23804\" xsd:anyURI" ]

rynl

2022-08-17T00:36:44Z

false

true

5

GO:0160044

160,044

sulfate:chloride antiporter activity

molecular_function

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(in) + sulfate(out) = chloride(out) + sulfate(in).

[ "PMID:17442754" ]

null

[]

[ "GO:0005452", "GO:0008271", "GO:0015108" ]

[]

[ "GO:0005452", "GO:0008271", "GO:0015108" ]

[]

rynl

2023-03-13T23:40:47Z

false

true

7

GO:0160045

160,045

TMEM240-body

cellular_component

A multilamellar subcellular structure formed in the cytoplasm of developing neuron, composed of Tmem240 and Emd proteins.

[ "PMID:32535204" ]

null

[ "T240-body" ]

[ "EXACT" ]

[]

[ "GO:0043231" ]

[]

[ "GO:0043231" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23835\" xsd:anyURI" ]

rynl

2022-08-18T00:42:10Z

false

true

8

GO:0160046

160,046

oxalate:chloride antiporter activity

molecular_function

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + oxalate(in) = chloride(in) + oxalate(out).

[ "PMID:17442754" ]

null

[]

[ "GO:0005452", "GO:0015108", "GO:0019531" ]

[]

[ "GO:0005452", "GO:0015108", "GO:0019531" ]

[]

rynl

2023-03-14T00:09:30Z

false

true

2

GO:0160047

160,047

muramyl dipeptide kinase activity

molecular_function

Catalysis of the reaction: ATP + muramyl dipeptide = ADP + H+ + 6-O-phospho-muramyl dipeptide.

[ "PMID:36002575" ]

null

[]

[ "RHEA:75935" ]

[ "GO:0016301" ]

[]

[ "GO:0016301" ]

[]

[ "skos:exactMatch RHEA:75935", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25141\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

rynl

2023-03-17T22:29:32Z

false

true

8

GO:0160049

160,049

negative regulation of cGAS/STING signaling pathway

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of cGAS/STING signaling pathway.

[ "PMID:29875158" ]

null

[]

[ "GO:0039532" ]

[ "negatively_regulates GO:0140896" ]

[ "negatively_regulates" ]

[ "GO:0140896" ]

[ "GO:0039532", "GO:0140896" ]

[ "GO:0065007", "negatively_regulates GO:0140896" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24016\" xsd:anyURI" ]

rynl

2022-09-19T23:17:52Z

false

true

2

GO:0160050

160,050

xanthine binding

molecular_function

Binding to xanthine, a purine base.

[ "PMID:32345632", "PMID:34125892" ]

null

[]

[ "GO:0002060" ]

[]

[ "GO:0002060" ]

[]

rynl

2022-09-27T17:42:21Z

false

true

8

GO:0160051

160,051

Cyc8(Ssn6)-Tup1 general repressor complex

cellular_component

A corepressor complex containing the WD-repeat protein Tup1p (S. cerevisiae) and Tup11/Tup12 (fission yeast) and the TPR repeat protein Cyc8p (S. cerevisiae) ssn6 (fission yeast) that is recruited to target genes by DNA-bound repressor proteins preferentially at regions where histones are deacetylated by the Clr6 class...

[ "GOC:vw", "PMID:10871883", "PMID:17101775", "PMID:22156212" ]

null

[ "Tup11/Tup12 repressor complex" ]

[ "EXACT" ]

[]

[ "GO:0090571" ]

[]

[ "GO:0090571" ]

[]

rynl

2022-09-27T18:30:09Z

false

true

9

GO:0160052

160,052

mitotic nuclear envelope segregation

biological_process

The mitotic cell cycle process in which the nuclear envelope, including nuclear pores, is equally distributed to the two daughter cells during the mitotic cell cycle.

[ "GOC:vw", "PMID:24184107" ]

null

[]

[ "GO:1903047" ]

[ "part_of GO:0140014" ]

[ "part_of" ]

[ "GO:0140014" ]

[ "GO:0140014", "GO:1903047" ]

[]

rynl

2022-09-27T20:58:32Z

false

true

2

GO:0160053

160,053

serine-based site-specific recombinase activity

molecular_function

Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphoseryl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a serine in the active site.

[ "PMID:16756503", "PMID:29316791" ]

null

[]

[ "GO:0009009" ]

[]

[ "GO:0009009" ]

[]

rynl

2022-09-29T00:22:28Z

false

true

8