LiteFold/GO · Datasets at Hugging Face

GO:0141178

141,178

symbiont-mediated evasion of recognition by host complement

biological_process

A process by which a symbiont avoids the effects of recognition by host complement by altering molecules on the symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:22825444", "PMID:25537831", "PMID:34887398" ]

null

[ "symbiont-mediated evasion of host complement" ]

[ "EXACT" ]

[]

[ "GO:0141177" ]

[]

[ "GO:0141177" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27250\" xsd:anyURI" ]

pg

2024-03-12T14:01:12Z

false

true

6

GO:0141179

141,179

symbiont-mediated evasion of recognition by host antimicrobial peptide

biological_process

A process by which a symbiont avoids the effects of recognition by a host antimicrobial peptide by altering molecules on the symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:11401964", "PMID:22966934", "PMID:25537831" ]

null

[]

[ "GO:0141177" ]

[]

[ "GO:0141177" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27250\" xsd:anyURI" ]

pg

2024-03-12T14:09:42Z

false

true

6

GO:0141184

141,184

symbiont-mediated activation of host anti-inflammatory cytokine signaling

biological_process

A process in which a symbiont subverts an anti-inflammatory cytokine signaling pathway in the host organism by initiating, promoting, or enhancing its activation.

[ "PMID:23284742", "PMID:27437422", "PMID:29924996" ]

null

[]

[ "GO:0052028" ]

[]

[ "GO:0052028" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27129\" xsd:anyURI" ]

pg

2024-03-19T13:30:47Z

false

true

6

GO:0141185

141,185

UFM1-modified protein reader activity

molecular_function

A molecular adaptor recognizes and binds a target protein containing a UFM1 modification and brings the target protein into contact with another protein to allow those proteins to function in a coordinated way.

[ "PMID:32537488", "PMID:36848233", "PMID:38383785", "PMID:38383789" ]

null

[ "UFM1 modified protein reader activity", "UFM1-dependent protein binding" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0140035" ]

[]

[ "GO:0140035" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27325\" xsd:anyURI" ]

pg

2024-03-22T08:49:54Z

false

true

2

GO:0141187

141,187

nucleic acid biosynthetic process

biological_process

The biosynthetic process resulting in the formation of a nucleic acid.

[ "GOC:dph", "GOC:tb" ]

This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term.

[]

[ "gocheck_do_not_annotate" ]

[]

[ "GO:0009059", "GO:0034654", "GO:0090304" ]

[]

[ "GO:0009059", "GO:0034654", "GO:0090304" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27408\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27633\" xsd:anyURI" ]

pg

2024-03-25T07:33:40Z

false

true

1

GO:0141188

141,188

nucleic acid catabolic process

biological_process

The cellular DNA metabolic process resulting in the breakdown of a nucleic acid.

[ "GOC:curators" ]

This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term.

[]

[ "gocheck_do_not_annotate" ]

[]

[ "GO:0009057", "GO:0034655", "GO:0090304" ]

[]

[ "GO:0009057", "GO:0034655", "GO:0090304" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27408\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27633\" xsd:anyURI" ]

pg

2024-03-25T07:35:06Z

false

true

2

GO:0141189

141,189

obsolete G protein mediated opsin signaling pathway

biological_process

OBSOLETE. A phospholipase C-activating receptor G protein-coupled receptor signaling pathway that starts with an opsin being activated by a photon, and ending with the light signal being trasmitted through the synapses. Opsins are G-protein coupled receptors which bind light-sensitive chromophores.

[ "PMID:19720651", "PMID:36272560" ]

This term was obsoleted because it was created by mistake; it represents the same process as G protein-mediated opsin signaling pathway ; GO:0030265.

[ "G protein-mediated opsin signaling pathway", "phospholipase C-activating G protein-mediated phototransduction signaling pathway", "phospholipase C-activating phototransduction signaling pathway", "phospholipase C-activating phototransduction-mediated G-protein coupled receptor signaling pathway", "phototra...

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0030265" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27415\" xsd:anyURI" ]

pg

2024-03-25T14:33:47Z

true

5

GO:0141190

141,190

transducin-mediated opsin signaling pathway

biological_process

A G protein-coupled receptor signaling pathway that starts with an opsin molecule being activated by a photon. Opsins include rhodopsin and others visual receptors bind heterotrimeric transducin G proteins upon activation. Activated transducin alpha-subunit activates cGMP phosphodiesterase, which breaks down cGMP. The ...

[ "PMID:19720651", "PMID:36272560", "PMID:36499010", "PMID:37159291" ]

null

[ "cGMP-mediated opsin signaling pathway", "cGMP-mediated rhodopsin signaling pathway", "ciliary opsin-mediated signaling pathway", "cyclic-GMP-mediated opsin signaling pathway", "cyclic-nucleotide-mediated opsin signaling pathway", "Gt-mediated opsin signaling pathway" ]

[ "EXACT", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0016056" ]

[]

[ "GO:0016056" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27415\" xsd:anyURI" ]

pg

2024-03-25T16:55:10Z

false

true

1

GO:0141191

141,191

negative regulation of HRI-mediated signaling

biological_process

Any process that stops, prevents, or reduces the frequency, rate or extent of HRI-mediated signaling.

[ "PMID:38297121" ]

null

[]

[ "GO:0065007" ]

[]

[ "GO:0065007" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27503\" xsd:anyURI" ]

pg

2024-04-09T06:36:57Z

false

true

6

GO:0141193

141,193

nuclear receptor-mediated signaling pathway

biological_process

The series of molecular signals initiated by a signaling molecule binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.

[ "PMID:25614732" ]

null

[ "nuclear receptor signaling pathway" ]

[ "EXACT" ]

[]

[ "GO:0030522" ]

[]

[ "GO:0030522" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27599\" xsd:anyURI" ]

pg

2024-04-12T13:08:13Z

false

true

9

GO:0141194

141,194

siRNA-mediated heterochromatin formation

biological_process

The formation of heterochromatin into a heterochromatin domain by a process mediated by a small interfering siRNA.

[ "GOC:ha", "GOC:pg" ]

null

[]

[ "GO:0031048" ]

[]

[ "GO:0031048" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27454\" xsd:anyURI" ]

pg

2024-04-22T12:56:08Z

false

true

8

GO:0141195

141,195

obsolete piRNA-mediated facultative heterochromatin formation

biological_process

OBSOLETE. The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a Piwi-associated RNA (piRNA).

[ "PMID:26494711" ]

This term was obsoleted because the evidence is too weak to implicate piRNAs in facultative heterochromatin formation.

[]

[ "GO:0140966" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27454\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27842\" xsd:anyURI" ]

pg

2024-04-22T13:37:21Z

true

7

GO:0141196

141,196

transposable element silencing by piRNA-mediated DNA methylation

biological_process

A transposable element silencing mechanism mediated by Piwi-associated RNA (piRNA)-directed DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription.

[ "PMID:32674113" ]

null

[ "retrotransposon silencing by piRNA-directed DNA methylation", "transposable element silencing by piRNA-directed DNA methylation" ]

[ "NARROW", "EXACT" ]

[]

[ "GO:0141005", "GO:0141176" ]

[]

[ "GO:0141005", "GO:0141176" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27454\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28924\" xsd:anyURI" ]

pg

2024-04-22T13:49:06Z

false

true

5

GO:0141197

141,197

4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)

molecular_function

Catalysis of the reaction: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H+ + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin].

[ "RHEA:43604" ]

null

[ "(E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase activity", "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity" ]

[ "BROAD", "BROAD" ]

[]

[ "EC:1.17.7.3", "KEGG_REACTION:R10859", "MetaCyc:RXN-15878", "RHEA:43604" ]

[ "GO:0052592" ]

[]

[ "GO:0052592" ]

[]

[ "skos:exactMatch EC:1.17.7.3", "skos:exactMatch RHEA:43604", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27696\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pg

2024-04-23T08:04:46Z

false

true

9

GO:0141198

141,198

protein branched polyubiquitination

biological_process

A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at various positions of the ubiquitin monomers, forming branched linkages, such as K11/K48- or K11/K63-linked chains.

[ "PMID:29033132", "PMID:29378950", "PMID:31998699", "PMID:37325469" ]

null

[]

[ "GO:0000209" ]

[]

[ "GO:0000209" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27503\" xsd:anyURI" ]

pg

2024-04-26T06:08:52Z

false

true

6

GO:0141199

141,199

obsolete GDP-mannose biosynthetic process from glucose

biological_process

OBSOLETE. The chemical reactions and pathways resulting in the formation of GDP-mannose from glucose.

[ "PMID:21273394", "PMID:9287314" ]

This term was obsoleted because it represents the same process as GDP-mannose biosynthetic process from fructose-6-phosphate ; GO:0061729.

[]

[ "GO:0061729" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27683\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28388\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28953\" xsd:anyURI" ]

pg

2024-04-26T08:43:27Z

true

4

GO:0141200

141,200

UTP thiamine diphosphokinase activity

molecular_function

Catalysis of the reaction: UTP + thiamine = UMP + thiamine diphosphate.

[ "PMID:38547260", "RHEA:79423" ]

null

[]

[ "RHEA:79423" ]

[ "GO:0016778" ]

[]

[ "GO:0016778" ]

[]

[ "skos:exactMatch RHEA:79423", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27518\" xsd:anyURI" ]

pg

2024-04-30T07:07:13Z

false

true

5

GO:0141201

141,201

pyroptotic cell death

biological_process

A inflammatory cell death process associated with the generation of pyrogenic mediators that result from the activation of gasdermins.

[ "PMID:18846107", "PMID:21760595", "PMID:33883744" ]

null

[ "pyroptosis" ]

[ "BROAD" ]

[]

[ "GO:0012501", "GO:0070269" ]

[]

[ "GO:0012501", "GO:0070269" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27753\" xsd:anyURI" ]

pg

2024-04-30T09:39:12Z

false

true

3

GO:0141203

141,203

symbiont-mediated suppression of host complement activation by activation of host proteases

biological_process

A process by which a symbiont prevents host complement activation by recruiting host proteases, destroying the complement before it has its effect on the symbiont.

[ "PMID:15792635", "PMID:26945067", "PMID:34305859" ]

null

[ "symbiont-mediated suppression of host complement activation by recruitment of host proteases" ]

[ "NARROW" ]

[]

[ "GO:0042784" ]

[]

[ "GO:0042784" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27788\" xsd:anyURI" ]

pg

2024-04-30T13:17:35Z

false

true

9

GO:0141204

141,204

dipeptide transmembrane transport from lysosomal lumen to cytosol

biological_process

The directed movement of dipeptide from the lysosomal lumen across the lysosomal membrane and into the cytosol.

[ "PMID:38507452" ]

null

[ "dipeptide export from lysosomal lumen", "dipeptide export from lysosome", "transmembrane dipeptide transport from lysosomal lumen to cytosol" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0015833", "GO:0170063" ]

[]

[ "GO:0015833", "GO:0170063" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27439\" xsd:anyURI" ]

pg

2024-05-02T08:07:26Z

false

true

3

GO:0141207

141,207

peptide lactyltransferase (ATP-dependent) activity

molecular_function

Catalysis of the reaction: lactate + ATP + L-lysyl-[protein] = N(6)-lactoyl-L-lysyl-[protein]+ AMP + diphosphate. Can also act on free lactate.

[ "PMID:38512451", "PMID:38653238", "RHEA:80271" ]

null

[ "peptide lactyltransferase (ATP dependent) activity", "peptide lactyltransferase activity" ]

[ "EXACT", "BROAD" ]

[]

[ "RHEA:80271", "RHEA:80275" ]

[ "GO:0016886", "GO:0140096" ]

[]

[ "GO:0016886", "GO:0140096" ]

[]

[ "skos:exactMatch RHEA:80271", "skos:narrowMatch RHEA:80275", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28015\" xsd:anyURI" ]

pg

2024-06-07T08:13:32Z

false

true

5

GO:0141208

141,208

NAD-dependent protein lysine delactylase activity

molecular_function

Catalysis of the reaction: H2O + N6-lactoyl-L-lysyl-[protein] + NAD = L-lysyl-[protein] + nicotinamide +2''-O-lactoyl-ADP-D-ribose, transfering a lactoyl group attached to a lysine residue in a protein to NAD.

[ "PMID:38512451", "RHEA:80287" ]

null

[ "protein lysine delactylase activity" ]

[ "BROAD" ]

[]

[ "RHEA:80287" ]

[ "GO:0034979" ]

[]

[ "GO:0034979" ]

[]

[ "skos:exactMatch RHEA:80287", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28015\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28920\" xsd:anyURI" ]

pg

2024-06-07T08:37:00Z

false

true

3

GO:0141209

141,209

oxysterol receptor signaling pathway

biological_process

A nuclear receptor-mediated signaling pathway initiated by an oxysterol binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.

[ "PMID:37541371", "PMID:9794827" ]

null

[ "intracellular oxysterol receptor signaling pathway", "nuclear receptor-mediated oxysterol signaling pathway" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0030518" ]

[]

[ "GO:0030518" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28037\" xsd:anyURI" ]

pg

2024-06-07T13:12:25Z

false

true

4

GO:0141213

141,213

symbiont-mediated generation of symbiont replication vacuole

biological_process

A process in which a symbiont alters or subverts vacuole organization in its host organism to form a protected environment in which it can replicate. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:21822290", "PMID:23186105", "PMID:30893609" ]

null

[]

[ "GO:0044075" ]

[]

[ "GO:0044075" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28420\" xsd:anyURI" ]

pg

2024-07-09T12:42:21Z

false

true

9

GO:0141214

141,214

positive regulation of phospholipase C/protein kinase C signal transduction

biological_process

Any process that activates or increases the frequency, rate or extent of phospholipase C/protein kinase C signal transduction.

[ "PMID:24008408", "PMID:32255775" ]

null

[ "positive regulation of PLC/PKC signal transduction" ]

[ "EXACT" ]

[]

[ "GO:1902533" ]

[ "positively_regulates GO:0141212" ]

[ "positively_regulates" ]

[ "GO:0141212" ]

[ "GO:0141212", "GO:1902533" ]

[ "GO:0065007", "positively_regulates GO:0141212" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28495\" xsd:anyURI" ]

pg

2024-07-15T14:17:50Z

false

true

9

GO:0141215

141,215

N-acetyltaurine hydrolase activity

molecular_function

Catalysis of the reaction: N-acetyltaurine + H2O = acetate + taurine.

[ "PMID:39112712", "RHEA:81107" ]

null

[]

[ "RHEA:81107" ]

[ "GO:0016788" ]

[]

[ "GO:0016788" ]

[]

[ "skos:exactMatch RHEA:81107", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28746\" xsd:anyURI" ]

pg

2024-08-23T09:58:14Z

false

true

8

GO:0141217

141,217

glycoRNA biosynthetic process

biological_process

The posttranscriptional addition of a carbohydrate or carbohydrate derivative unit to residues in an RNA molecule. GlycoRNA consists of RNAs modified with secretory N-glycans that are presented on the cell surface.

[ "PMID:34004145", "PMID:39173631" ]

null

[ "glycoRNA biosynthesis", "RNA glycosylation" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0006396" ]

[]

[ "GO:0006396" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27105\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30506\" xsd:anyURI" ]

pg

2024-09-19T09:47:24Z

false

true

8

GO:0141221

141,221

histone deacetylase activity, hydrolytic mechanism

molecular_function

Catalysis of the reaction: H2O + N6-acetyl-L-lysyl-[histone] = acetate + L-lysyl-[histone].

[ "PMID:24691964", "PMID:28450737", "RHEA:58196" ]

Histone deacytylase (HDAC) enzymes are divided into four classes: the Class I Rpd3-like proteins (in human: HDAC1, HDAC2, HDAC3, and HDAC8); the Class II Hda1-like proteins (in human: HDAC4, HDAC5, HDAC6, HDAC7, HDAC9, and HDAC10); the Class III Sir2-like proteins (in human: SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, an...

[ "histone deacetylase activity", "histone deacetylase activity, NAD-independent" ]

[ "BROAD", "EXACT" ]

[]

[ "EC:3.5.1.98", "MetaCyc:3.5.1.98-RXN", "RHEA:58196" ]

[ "GO:0004407", "GO:0016811" ]

[]

[ "GO:0004407", "GO:0016811" ]

[]

[ "skos:exactMatch EC:3.5.1.98", "skos:exactMatch RHEA:58196", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22836\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29468\" xsd:anyURI" ]

pg

2024-09-20T12:31:22Z

false

true

4

GO:0141223

141,223

cysteine synthase activity, acting on O-succinyl-L-serine

molecular_function

Catalysis of the reaction: hydrogen sulfide + O-succinyl-L-serine = L-cysteine + succinate.

[ "RHEA:53816" ]

null

[ "cysteine synthase activity" ]

[ "BROAD" ]

[]

[ "RHEA:53816" ]

[ "GO:0016765" ]

[]

[ "GO:0016765" ]

[]

[ "skos:exactMatch RHEA:53816", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28833\" xsd:anyURI" ]

pg

2024-10-28T07:48:43Z

false

true

8

GO:0150001

150,001

primary dendrite

cellular_component

A dendrite emerging from the cell body (the soma) of a neuron.

[ "GOC:aruk", "GOC:bc" ]

null

[]

[ "GO:0030425" ]

[]

[ "GO:0030425" ]

[]

null

false

true

3

GO:0150002

150,002

distal dendrite

cellular_component

The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma).

[ "GOC:aruk", "GOC:bc", "PMID:20629984" ]

null

[]

[ "GO:0030425" ]

[]

[ "GO:0030425" ]

[]

null

false

true

4

GO:0150003

150,003

regulation of spontaneous synaptic transmission

biological_process

Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission.

[ "GOC:aruk", "GOC:bc", "PMID:15457210" ]

null

[]

[ "GO:0050804" ]

[ "regulates GO:0098814" ]

[ "regulates" ]

[ "GO:0098814" ]

[ "GO:0050804", "GO:0098814" ]

[ "GO:0065007", "regulates GO:0098814" ]

[]

null

false

true

3

GO:0150004

150,004

dendritic spine origin

cellular_component

The part of the dendritic spine neck where the spine arises from the dendritic shaft.

[ "GOC:aruk", "GOC:bc", "PMID:9030614" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0044326" ]

[ "part_of" ]

[ "GO:0044326" ]

[ "GO:0044326", "GO:0110165" ]

[]

null

false

true

9

GO:0150005

150,005

enzyme activator complex

cellular_component

A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active.

[ "GOC:bhm", "PMID:16244137", "PMID:28710280" ]

null

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

null

false

true

7

GO:0150006

150,006

urease activator complex

cellular_component

A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function.

[ "GOC:bhm", "PMID:16244137", "PMID:28710280" ]

null

[]

[ "GO:0150005" ]

[]

[ "GO:0150005" ]

[]

null

false

true

2

GO:0150008

150,008

bulk synaptic vesicle endocytosis

biological_process

Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse.

[ "GOC:aruk", "GOC:bc", "GOC:ha", "PMID:18250322", "PMID:18579735", "PMID:19266323", "PMID:26430111", "PMID:28391090" ]

null

[ "activity-dependent bulk endocytosis", "activity-dependent bulk synaptic vesicle endocytosis", "ADBE", "bulk endocytosis" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0048488" ]

[]

[ "GO:0048488" ]

[]

bc

2017-12-01T10:20:18Z

false

true

8

GO:0150011

150,011

regulation of neuron projection arborization

biological_process

Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.

[ "GOC:aruk", "GOC:bc", "PMID:17114044" ]

null

[ "regulation of neurite arborization", "regulation of neurite branching", "regulation of neuron projection branching" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0022604", "GO:0031344" ]

[ "regulates GO:0140058" ]

[ "regulates" ]

[ "GO:0140058" ]

[ "GO:0022604", "GO:0031344", "GO:0140058" ]

[ "GO:0065007", "regulates GO:0140058" ]

[]

bc

2017-12-13T16:32:34Z

false

true

8

GO:0150012

150,012

positive regulation of neuron projection arborization

biological_process

Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.

[ "GOC:aruk", "GOC:bc", "PMID:17114044" ]

null

[ "positive regulation of neurite arborization", "positive regulation of neurite branching", "positive regulation of neuron projection branching" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0031346", "GO:0051094", "GO:0150011" ]

[ "positively_regulates GO:0140058" ]

[ "positively_regulates" ]

[ "GO:0140058" ]

[ "GO:0031346", "GO:0051094", "GO:0140058", "GO:0150011" ]

[ "GO:0065007", "positively_regulates GO:0140058" ]

[]

bc

2017-12-13T16:46:57Z

false

true

7

GO:0150013

150,013

negative regulation of neuron projection arborization

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.

[ "GOC:aruk", "GOC:bc", "PMID:17114044" ]

null

[ "negative regulation of neurite arborization", "negative regulation of neurite branching", "negative regulation of neuron projection branching" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0031345", "GO:0051093", "GO:0150011" ]

[ "negatively_regulates GO:0140058" ]

[ "negatively_regulates" ]

[ "GO:0140058" ]

[ "GO:0031345", "GO:0051093", "GO:0140058", "GO:0150011" ]

[ "GO:0065007", "negatively_regulates GO:0140058" ]

[]

bc

2017-12-13T16:50:53Z

false

true

2

GO:0150014

150,014

apical distal dendrite

cellular_component

Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma).

[ "GO:bc", "GOC:aruk", "PMID:1720142", "PMID:20629984", "PMID:9214543" ]

null

[]

[ "GO:0097440", "GO:0150002" ]

[]

[ "GO:0097440", "GO:0150002" ]

[]

bc

2017-12-21T12:03:28Z

false

true

8

GO:0150016

150,016

basal distal dendrite

cellular_component

Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma).

[ "GOC:aruk", "GOC:bc", "PMID:17046728", "PMID:1720142", "PMID:20629984", "PMID:22683681", "PMID:9214543" ]

null

[]

[ "GO:0097441", "GO:0150002" ]

[]

[ "GO:0097441", "GO:0150002" ]

[]

bc

2017-12-21T12:11:47Z

false

true

8

GO:0150017

150,017

basal proximal dendrite

cellular_component

Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma).

[ "GOC:aruk", "GOC:bc", "PMID:16899232", "PMID:17046728", "PMID:1720142", "PMID:22683681", "PMID:9214543" ]

null

[]

[ "GO:0097441", "GO:1990635" ]

[]

[ "GO:0097441", "GO:1990635" ]

[]

bc

2017-12-21T12:17:00Z

false

true

2

GO:0150018

150,018

basal dendrite development

biological_process

The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure.

[ "GOC:aruk", "GOC:bc", "PMID:22683681" ]

null

[]

[ "GO:0016358" ]

[]

[ "GO:0016358" ]

[]

bc

2017-12-22T11:09:53Z

false

true

3

GO:0150019

150,019

basal dendrite morphogenesis

biological_process

The process in which the anatomical structures of a basal dendrite are generated and organized.

[ "GOC:aruk", "GOC:bc", "PMID:22683681" ]

null

[]

[ "GO:0048813" ]

[ "part_of GO:0150018" ]

[ "part_of" ]

[ "GO:0150018" ]

[ "GO:0048813", "GO:0150018" ]

[]

bc

2017-12-22T11:26:07Z

false

true

6

GO:0150020

150,020

basal dendrite arborization

biological_process

The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches.

[ "GOC:aruk", "GOC:bc", "PMID:22683681" ]

null

[]

[ "GO:0140059", "GO:0150019" ]

[]

[ "GO:0140059", "GO:0150019" ]

[]

bc

2017-12-22T11:32:31Z

false

true

7

GO:0150021

150,021

apical dendrite morphogenesis

biological_process

The process in which the anatomical structures of an apical dendrite are generated and organized.

[ "GOC:aruk", "GOC:bc", "PMID:22683681" ]

null

[]

[ "GO:0048813" ]

[ "part_of GO:0150022" ]

[ "part_of" ]

[ "GO:0150022" ]

[ "GO:0048813", "GO:0150022" ]

[]

bc

2017-12-22T11:50:00Z

false

true

2

GO:0150022

150,022

apical dendrite development

biological_process

The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure.

[ "GOC:aruk", "GOC:bc", "PMID:22683681" ]

null

[]

[ "GO:0016358" ]

[]

[ "GO:0016358" ]

[]

bc

2017-12-22T11:52:40Z

false

true

3

GO:0150023

150,023

apical dendrite arborization

biological_process

The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches.

[ "GOC:aruk", "GOC:bc", "PMID:22683681" ]

null

[]

[ "GO:0140059", "GO:0150021" ]

[]

[ "GO:0140059", "GO:0150021" ]

[]

bc

2017-12-22T11:56:05Z

false

true

1

GO:0150024

150,024

oxidised low-density lipoprotein particle clearance

biological_process

The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.

[ "GOC:aruk", "GOC:bc", "PMID:27607416" ]

null

[ "ox-LDL particle clearance", "oxidised LDL particle clearance", "oxidized LDL particle clearance", "oxidized low-density lipoprotein particle clearance", "oxLDL particle clearance" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0034381" ]

[]

[ "GO:0034381" ]

[]

bc

2018-02-05T16:14:05Z

false

true

5

GO:0150025

150,025

oxidised low-density lipoprotein particle receptor activity

molecular_function

Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis.

[ "GOC:aruk", "GOC:bc", "PMID:27607416" ]

null

[ "ox-LDL particle receptor activity", "ox-LDL receptor activity", "oxidised LDL particle receptor activity", "oxidised LDL receptor activity", "oxidised low-density lipoprotein receptor activity", "oxidized LDL particle receptor activity", "oxidized LDL receptor activity", "oxidized low-density lipopro...

[ "EXACT", "RELATED", "EXACT", "RELATED", "RELATED", "EXACT", "RELATED", "EXACT", "RELATED", "EXACT", "RELATED" ]

[]

[ "GO:0030228" ]

[]

[ "GO:0030228" ]

[]

bc

2018-02-06T14:17:33Z

false

true

3

GO:0150031

150,031

regulation of protein localization to lysosome

biological_process

Any process that modulates the frequency, rate or extent of protein localization to lysosome.

[ "GOC:aruk", "GOC:bc", "PMID:24305806" ]

null

[]

[ "GO:0032880" ]

[ "regulates GO:0061462" ]

[ "regulates" ]

[ "GO:0061462" ]

[ "GO:0032880", "GO:0061462" ]

[ "GO:0065007", "regulates GO:0061462" ]

[]

bc

2018-02-06T17:07:03Z

false

true

4

GO:0150032

150,032

positive regulation of protein localization to lysosome

biological_process

Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.

[ "GOC:aruk", "GOC:bc" ]

null

[]

[ "GO:0150031", "GO:1903829" ]

[ "positively_regulates GO:0061462" ]

[ "positively_regulates" ]

[ "GO:0061462" ]

[ "GO:0061462", "GO:0150031", "GO:1903829" ]

[ "GO:0065007", "positively_regulates GO:0061462" ]

[]

bc

2018-02-06T17:11:02Z

false

true

7

GO:0150033

150,033

negative regulation of protein localization to lysosome

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.

[ "GOC:aruk", "GOC:bc", "PMID:24305806" ]

null

[]

[ "GO:0150031", "GO:1903828" ]

[ "negatively_regulates GO:0061462" ]

[ "negatively_regulates" ]

[ "GO:0061462" ]

[ "GO:0061462", "GO:0150031", "GO:1903828" ]

[ "GO:0065007", "negatively_regulates GO:0061462" ]

[]

bc

2018-02-06T17:14:16Z

false

true

5

GO:0150034

150,034

distal axon

cellular_component

That part of an axon close to and including the growth cone or the axon terminus.

[ "GOC:aruk", "GOC:bc", "PMID:17202468" ]

null

[ "distal part of axon", "distal part of the axon" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0110165" ]

[ "part_of GO:0030424" ]

[ "part_of" ]

[ "GO:0030424" ]

[ "GO:0030424", "GO:0110165" ]

[]

bc

2018-02-19T15:04:24Z

false

true

3

GO:0150035

150,035

regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission

biological_process

Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission.

[ "GOC:aruk", "GOC:bc", "PMID:19448629" ]

Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.

[]

[ "goslim_synapse" ]

[]

[ "GO:0050804" ]

[ "regulates GO:0099183" ]

[ "regulates" ]

[ "GO:0099183" ]

[ "GO:0050804", "GO:0099183" ]

[ "GO:0065007", "regulates GO:0099183" ]

[]

bc

2018-04-17T13:56:34Z

false

true

6

GO:0150036

150,036

regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission

biological_process

Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission.

[ "GOC:aruk", "GOC:bc", "PMID:27296803" ]

Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.

[]

[ "goslim_synapse" ]

[]

[ "GO:0050804" ]

[ "regulates GO:0099553" ]

[ "regulates" ]

[ "GO:0099553" ]

[ "GO:0050804", "GO:0099553" ]

[ "GO:0065007", "regulates GO:0099553" ]

[]

bc

2018-04-18T09:54:49Z

false

true

7

GO:0150037

150,037

regulation of calcium-dependent activation of synaptic vesicle fusion

biological_process

Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion.

[ "GOC:aruk", "GOC:bc", "PMID:27052163" ]

null

[]

[ "goslim_synapse" ]

[]

[ "GO:0031630" ]

[ "regulates GO:0099502" ]

[ "regulates" ]

[ "GO:0099502" ]

[ "GO:0031630", "GO:0099502" ]

[ "GO:0065007", "regulates GO:0099502" ]

[]

bc

2018-04-18T12:47:38Z

false

true

5

GO:0150038

150,038

postsynaptic dense core vesicle exocytosis

biological_process

The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels.

[ "GOC:aruk", "GOC:bc", "PMID:19448629" ]

null

[]

[ "goslim_synapse" ]

[]

[ "GO:0099003", "GO:0099011" ]

[ "occurs_in GO:0098794" ]

[ "occurs_in" ]

[ "GO:0098794" ]

[ "GO:0098794", "GO:0099003", "GO:0099011" ]

[ "GO:0099011", "occurs_in GO:0098794" ]

[]

bc

2018-04-18T14:32:16Z

false

true

6

GO:0150043

150,043

structural constituent of synapse-associated extracellular matrix

molecular_function

The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.

[ "GOC:aruk", "GOC:bc", "PMID:17189701" ]

null

[ "extra-synaptic extracellular matrix structural constituent", "structural constituent of extra-synaptic extracellular matrix", "synapse-associated extracellular matrix structural constituent" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "goslim_synapse" ]

[]

[ "GO:0005201" ]

[ "occurs_in GO:0099535" ]

[ "occurs_in" ]

[ "GO:0099535" ]

[ "GO:0005201", "GO:0099535" ]

[ "GO:0005201", "occurs_in GO:0099535" ]

[]

bc

2018-04-19T13:42:40Z

false

true

2

GO:0150044

150,044

regulation of postsynaptic dense core vesicle exocytosis

biological_process

Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis.

[ "GOC:aruk", "GOC:bc", "PMID:19448629" ]

null

[]

[ "goslim_synapse" ]

[]

[ "GO:1905413" ]

[ "regulates GO:0150038" ]

[ "regulates" ]

[ "GO:0150038" ]

[ "GO:0150038", "GO:1905413" ]

[ "GO:0065007", "regulates GO:0150038" ]

[]

bc

2018-04-20T13:34:32Z

false

true

1

GO:0150045

150,045

regulation of synaptic signaling by nitric oxide

biological_process

Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide.

[ "GOC:aruk", "GOC:bc", "PMID:26311509" ]

null

[]

[ "goslim_synapse" ]

[]

[ "GO:0010646", "GO:0023051" ]

[ "regulates GO:0099163" ]

[ "regulates" ]

[ "GO:0099163" ]

[ "GO:0010646", "GO:0023051", "GO:0099163" ]

[ "GO:0065007", "regulates GO:0099163" ]

[]

bc

2018-04-23T09:42:25Z

false

true

2

GO:0150047

150,047

obsolete G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential

molecular_function

OBSOLETE. G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential.

[ "GOC:aruk", "GOC:bc", "PMID:11498050" ]

The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.

[ "G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential" ]

[ "EXACT" ]

[]

[ "GO:0099528" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31205\" xsd:anyURI" ]

bc

2018-04-23T10:51:20Z

true

5

GO:0150048

150,048

cerebellar granule cell to Purkinje cell synapse

cellular_component

A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum.

[ "GOC:aruk", "GOC:bc", "PMID:12427822" ]

null

[ "cerebellar parallel fiber to Purkinje cell synapse" ]

[ "EXACT" ]

[]

[ "goslim_synapse" ]

[]

[ "GO:0098985" ]

[]

[ "GO:0098985" ]

[]

bc

2018-04-23T14:44:40Z

false

true

6

GO:0150051

150,051

postsynaptic Golgi apparatus

cellular_component

The network of the Golgi apparatus structures located within the postsynapse.

[ "GOC:aruk", "GOC:bc", "PMID:23838184" ]

null

[ "Golgi outpost" ]

[ "RELATED" ]

[]

[ "goslim_synapse" ]

[]

[ "GO:0005794" ]

[ "part_of GO:0098794" ]

[ "part_of" ]

[ "GO:0098794" ]

[ "GO:0005794", "GO:0098794" ]

[]

bc

2018-05-08T15:42:56Z

false

true

7

GO:0150052

150,052

regulation of postsynapse assembly

biological_process

Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse.

[ "GOC:aruk", "GOC:bc", "PMID:16394100", "PMID:16672654", "PMID:28185854" ]

null

[]

[ "goslim_synapse" ]

[]

[ "GO:0051963", "GO:0099175" ]

[ "regulates GO:0099068" ]

[ "regulates" ]

[ "GO:0099068" ]

[ "GO:0051963", "GO:0099068", "GO:0099175" ]

[ "GO:0065007", "regulates GO:0099068" ]

[]

bc

2018-05-08T16:38:55Z

false

true

7

GO:0150053

150,053

cerebellar climbing fiber to Purkinje cell synapse

cellular_component

A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata.

[ "GOC:aruk", "GOC:bc", "PMID:19597563", "PMID:23811844", "PMID:5044254" ]

null

[ "cerebellar climbing fibre to Purkinje cell synapse" ]

[ "EXACT" ]

[]

[ "goslim_synapse" ]

[]

[ "GO:0098985" ]

[]

[ "GO:0098985" ]

[]

bc

2018-05-09T09:57:20Z

false

true

1

GO:0150054

150,054

regulation of postsynaptic neurotransmitter receptor diffusion trapping

biological_process

Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping.

[ "GOC:aruk", "GOC:bc", "PMID:20935643" ]

null

[]

[ "goslim_synapse" ]

[]

[ "GO:0060341", "GO:0065008", "GO:1902683" ]

[ "regulates GO:0098970" ]

[ "regulates" ]

[ "GO:0098970" ]

[ "GO:0060341", "GO:0065008", "GO:0098970", "GO:1902683" ]

[ "GO:0065007", "regulates GO:0098970" ]

[]

bc

2018-05-10T14:26:59Z

false

true

9

GO:0150056

150,056

amylin receptor complex 1

cellular_component

A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/AD...

[ "GOC:aruk", "GOC:bc", "PMID:22500019" ]

null

[ "AMY1 complex" ]

[ "EXACT" ]

[]

[ "GO:1903440" ]

[]

[ "GO:1903440" ]

[]

bc

2018-06-21T10:47:10Z

false

true

9

GO:0150057

150,057

amylin receptor complex 2

cellular_component

A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM).

[ "GOC:aruk", "GOC:bc", "PMID:22500019" ]

null

[ "AMY2 complex" ]

[ "EXACT" ]

[]

[ "GO:1903440" ]

[]

[ "GO:1903440" ]

[]

bc

2018-06-21T10:51:35Z

false

true

7

GO:0150058

150,058

amylin receptor complex 3

cellular_component

A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in inc...

[ "GOC:aruk", "GOC:bc", "PMID:22500019" ]

null

[ "AMY3 complex" ]

[ "EXACT" ]

[]

[ "GO:1903440" ]

[]

[ "GO:1903440" ]

[]

bc

2018-06-21T10:54:00Z

false

true

6

GO:0150059

150,059

amylin receptor 1 signaling pathway

biological_process

The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (...

[ "GOC:aruk", "GOC:bc", "PMID:22500019" ]

null

[ "AMY1 signaling pathway" ]

[ "EXACT" ]

[]

[ "GO:0097647" ]

[]

[ "GO:0097647" ]

[]

bc

2018-06-21T10:58:02Z

false

true

9

GO:0150060

150,060

amylin receptor 2 signaling pathway

biological_process

The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM).

[ "GOC:aruk", "GOC:bc", "PMID:22500019" ]

null

[ "AMY2 signaling pathway" ]

[ "EXACT" ]

[]

[ "GO:0097647" ]

[]

[ "GO:0097647" ]

[]

bc

2018-06-21T11:00:22Z

false

true

5

GO:0150061

150,061

amylin receptor 3 signaling pathway

biological_process

The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased ...

[ "GOC:aruk", "GOC:bc", "PMID:22500019" ]

null

[ "AMY3 signaling pathway" ]

[ "EXACT" ]

[]

[ "GO:0097647" ]

[]

[ "GO:0097647" ]

[]

bc

2018-06-21T11:02:09Z

false

true

7

GO:0150062

150,062

complement-mediated synapse pruning

biological_process

Synaptic pruning mediated by complement system signaling.

[ "GOC:aruk", "GOC:bc", "PMID:18083105", "PMID:22632727", "PMID:29844190" ]

null

[ "complement-dependent synapse pruning", "synapse clearance", "synapse disassembly", "synapse elimination", "synapse removal" ]

[ "EXACT", "BROAD", "BROAD", "BROAD", "BROAD" ]

[]

[ "GO:0098883" ]

[]

[ "GO:0098883" ]

[]

bc

2018-07-16T17:44:59Z

false

true

6

GO:0150063

150,063

visual system development

biological_process

The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.

[ "GOC:aruk", "GOC:bc", "GOC:krc", "PMID:15004427", "PMID:20647017", "PMID:22632727" ]

null

[ "optic pathway development", "visual pathway development" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0048880" ]

[]

[ "GO:0048880" ]

[]

bc

2018-07-23T10:31:58Z

false

true

1

GO:0150065

150,065

regulation of deacetylase activity

biological_process

Any process that modulates the frequency, rate or extent of deacetylase activity.

[ "GOC:aruk", "GOC:bc", "PMID:19457097" ]

null

[]

[ "gocheck_obsoletion_candidate" ]

[]

[ "GO:0050790" ]

[ "regulates GO:0019213" ]

[ "regulates" ]

[ "GO:0019213" ]

[ "GO:0019213", "GO:0050790" ]

[ "GO:0065007", "regulates GO:0019213" ]

[]

bc

2018-07-23T12:24:28Z

false

true

8

GO:0150066

150,066

obsolete negative regulation of deacetylase activity

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity.

[ "GOC:aruk", "GOC:bc", "PMID:19457097" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]

bc

2018-07-23T12:37:57Z

true

1

GO:0150067

150,067

obsolete regulation of tubulin deacetylase activity

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of tubulin deacetylase activity.

[ "GOC:aruk", "GOC:bc", "PMID:19457097" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]

bc

2018-07-24T10:29:49Z

true

4

GO:0150068

150,068

obsolete positive regulation of tubulin deacetylase activity

biological_process

OBSOLETE. Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity.

[ "GOC:aruk", "GOC:bc" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]

bc

2018-07-24T10:35:51Z

true

9

GO:0150069

150,069

obsolete negative regulation of tubulin deacetylase activity

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity.

[ "GOC:aruk", "GOC:bc", "PMID:19457097" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]

bc

2018-07-24T10:40:19Z

true

1

GO:0150070

150,070

obsolete regulation of arginase activity

biological_process

OBSOLETE. Any process that modulates the frequency, rate or extent of arginase activity.

[ "GOC:aruk", "GOC:bc", "PMID:26670206" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22455\" xsd:anyURI" ]

bc

2018-07-25T09:17:30Z

true

3

GO:0150071

150,071

obsolete negative regulation of arginase activity

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity.

[ "GOC:aruk", "GOC:bc" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]

bc

2018-07-25T09:22:32Z

true

5

GO:0150074

150,074

positive regulation of protein-glutamine gamma-glutamyltransferase activity

biological_process

Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.

[ "GOC:aruk", "GOC:bc", "PMID:26670206" ]

null

[]

[ "gocheck_obsoletion_candidate" ]

[]

[ "GO:0043085", "GO:0051338" ]

[ "positively_regulates GO:0003810" ]

[ "positively_regulates" ]

[ "GO:0003810" ]

[ "GO:0003810", "GO:0043085", "GO:0051338" ]

[ "GO:0065007", "positively_regulates GO:0003810" ]

[]

bc

2018-07-25T10:08:19Z

false

true

9

GO:0150075

150,075

obsolete negative regulation of protein-glutamine gamma-glutamyltransferase activity

biological_process

OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.

[ "GOC:aruk", "GOC:bc" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]

bc

2018-07-25T10:10:24Z

true

7

GO:0150076

150,076

neuroinflammatory response

biological_process

The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.

[ "GOC:aruk", "GOC:bc", "PMID:10981966", "PMID:11099416", "PMID:18164423" ]

null

[ "nerve tissue inflammatory response", "nervous tissue inflammatory response", "neural tissue inflammatory response" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006954" ]

[]

[ "GO:0006954" ]

[]

bc

2018-07-26T12:25:34Z

false

true

8

GO:0150077

150,077

regulation of neuroinflammatory response

biological_process

Any process that modulates the frequency, rate or extent of neuroinflammatory response.

[ "GOC:aruk", "GOC:bc", "PMID:10981966", "PMID:11099416", "PMID:18164423" ]

null

[]

[ "GO:0050727" ]

[ "regulates GO:0150076" ]

[ "regulates" ]

[ "GO:0150076" ]

[ "GO:0050727", "GO:0150076" ]

[ "GO:0065007", "regulates GO:0150076" ]

[]

bc

2018-07-26T12:32:18Z

false

true

1

GO:0150078

150,078

positive regulation of neuroinflammatory response

biological_process

Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.

[ "GOC:aruk", "GOC:bc" ]

null

[]

[ "GO:0050729", "GO:0150077" ]

[ "positively_regulates GO:0150076" ]

[ "positively_regulates" ]

[ "GO:0150076" ]

[ "GO:0050729", "GO:0150076", "GO:0150077" ]

[ "GO:0065007", "positively_regulates GO:0150076" ]

[]

bc

2018-07-26T12:35:50Z

false

true

5

GO:0150079

150,079

negative regulation of neuroinflammatory response

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.

[ "GOC:aruk", "GOC:bc", "PMID:11099416", "PMID:18164423" ]

null

[]

[ "GO:0050728", "GO:0150077" ]

[ "negatively_regulates GO:0150076" ]

[ "negatively_regulates" ]

[ "GO:0150076" ]

[ "GO:0050728", "GO:0150076", "GO:0150077" ]

[ "GO:0065007", "negatively_regulates GO:0150076" ]

[]

bc

2018-07-26T12:38:08Z

false

true

5

GO:0150086

150,086

multiple synapse bouton

cellular_component

A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.

[ "GOC:aruk", "GOC:bc", "PMID:10586883", "PMID:11248111", "PMID:11466428", "PMID:18501438", "PMID:22028887", "PMID:29774619", "PMID:7482800", "PMID:8366344" ]

null

[ "MSB", "multi-synapse", "multi-synapse bouton", "multi-synaptic bouton", "multiple spine synapse bouton", "multiple synapse", "multiple-synapse bouton", "multisynapse", "multisynapse bouton", "multisynaptic bouton" ]

[ "EXACT", "RELATED", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "RELATED", "EXACT", "EXACT" ]

[]

[ "GO:0043195" ]

[]

[ "GO:0043195" ]

[]

bc

2018-08-08T13:21:17Z

false

true

2

GO:0150087

150,087

multiple synapse bouton, contacting single dendrite

cellular_component

A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite.

[ "GOC:aruk", "GOC:bc", "PMID:10586883", "PMID:11248111", "PMID:22028887", "PMID:24487234" ]

null

[ "MSB1", "type 1 multi-synapse bouton", "type 1 multi-synaptic bouton", "type 1 multiple spine synapse bouton", "type 1 multiple-synapse bouton", "type 1 multisynapse bouton", "type 1 multisynaptic bouton" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0150086" ]

[]

[ "GO:0150086" ]

[]

bc

2018-08-08T13:26:34Z

false

true

4

GO:0150088

150,088

multiple synapse bouton, contacting multiple dendrites

cellular_component

A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites.

[ "GOC:aruk", "GOC:bc", "PMID:10586883", "PMID:11248111", "PMID:22028887", "PMID:24487234", "PMID:7482800", "PMID:8366344" ]

null

[ "MSB2", "type 2 multi-synapse bouton", "type 2 multi-synaptic bouton", "type 2 multiple spine synapse bouton", "type 2 multiple-synapse bouton", "type 2 multisynapse bouton", "type 2 multisynaptic bouton" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0150086" ]

[]

[ "GO:0150086" ]

[]

bc

2018-08-08T13:31:43Z

false

true

6

GO:0150089

150,089

multiple spine synapse organization

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines.

[ "GOC:aruk", "GOC:bc", "PMID:10586883", "PMID:11248111", "PMID:11466428", "PMID:18501438", "PMID:22028887", "PMID:29774619", "PMID:7482800", "PMID:8366344" ]

null

[ "multi-synapse organisation", "multi-synapse organization", "multi-synaptic organisation", "multi-synaptic organization", "multiple spine synapse organisation", "multisynapse organisation", "multisynapse organization", "multisynaptic organisation", "multisynaptic organization" ]

[ "BROAD", "BROAD", "BROAD", "BROAD", "EXACT", "BROAD", "BROAD", "BROAD", "BROAD" ]

[]

[ "GO:0050808" ]

[]

[ "GO:0050808" ]

[]

bc

2018-08-08T14:54:50Z

false

true

5

GO:0150090

150,090

multiple spine synapse organization, single dendrite

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite.

[ "GOC:aruk", "GOC:bc", "PMID:10586883", "PMID:11248111", "PMID:22028887", "PMID:24487234" ]

null

[]

[ "GO:0150089" ]

[]

[ "GO:0150089" ]

[]

bc

2018-08-08T14:59:49Z

false

true

7

GO:0150091

150,091

multiple spine synapse organization, multiple dendrites

biological_process

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.

[ "GOC:aruk", "GOC:bc", "PMID:10586883", "PMID:11248111", "PMID:22028887", "PMID:24487234", "PMID:7482800", "PMID:8366344" ]

null

[]

[ "GO:0150089" ]

[]

[ "GO:0150089" ]

[]

bc

2018-08-08T15:05:29Z

false

true

9

GO:0150092

150,092

regulation of synaptic scaling

biological_process

A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell.

[ "GOC:aruk", "GOC:bc", "PMID:14630218", "PMID:14735113", "PMID:16547515" ]

null

[ "homeostatic synaptic scaling", "regulation of homeostatic synaptic scaling" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0048167" ]

[]

[ "GO:0048167" ]

[]

bc

2018-08-09T16:27:28Z

false

true

7

GO:0150093

150,093

amyloid-beta clearance by transcytosis

biological_process

The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.

[ "GOC:aruk", "GOC:bc", "PMID:26005850" ]

null

[]

[ "GO:0045056", "GO:0097242" ]

[]

[ "GO:0045056", "GO:0097242" ]

[]

bc

2018-08-16T14:33:47Z

false

true

2

GO:0150098

150,098

glial cell-neuron signaling

biological_process

Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or...

[ "GOC:aruk", "GOC:bc", "PMID:14980203", "PMID:16144764", "PMID:16547515", "PMID:18685038", "PMID:27788368", "PMID:9459440" ]

null

[ "glia-neuron signaling", "glia-neuron signalling", "glia-neurone signaling", "glia-neurone signalling", "glial cell- neuron signalling", "glial cell-neurone signalling", "glial cell-neurone singaling" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0007267" ]

[]

[ "GO:0007267" ]

[]

bc

2018-12-17T12:28:09Z

false

true

3

GO:0150099

150,099

neuron-glial cell signaling

biological_process

Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine.

[ "GOC:aruk", "GOC:bc", "PMID:10195197", "PMID:10196584", "PMID:10377338", "PMID:10493741", "PMID:11356870", "PMID:11399439", "PMID:15252819", "PMID:27788368" ]

null

[ "neuron-glia signaling", "neuron-glia signalling", "neuron-glial cell signalling", "neurone-glia signaling", "neurone-glia signalling", "neurone-glial cell signaling", "neurone-glial cell signalling" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0007267" ]

[]

[ "GO:0007267" ]

[]

bc

2018-12-17T12:30:12Z

false

true

4

GO:0150101

150,101

regulation of microtubule anchoring at centrosome

biological_process

Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome.

[ "GOC:aruk", "GOC:bc", "PMID:17139249" ]

null

[]

[ "GO:0070507" ]

[ "regulates GO:0034454" ]

[ "regulates" ]

[ "GO:0034454" ]

[ "GO:0034454", "GO:0070507" ]

[ "GO:0065007", "regulates GO:0034454" ]

[]

bc

2019-04-17T11:24:52Z

false

true

9

GO:0150102

150,102

negative regulation of monocyte activation

biological_process

Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation.

[ "GOC:aruk", "PMID:15597323" ]

null

[ "repression of monocyte activation" ]

[ "EXACT" ]

[]

[ "GO:0002695" ]

[ "negatively_regulates GO:0042117" ]

[ "negatively_regulates" ]

[ "GO:0042117" ]

[ "GO:0002695", "GO:0042117" ]

[ "GO:0065007", "negatively_regulates GO:0042117" ]

[]

bc

2019-04-26T20:01:24Z

false

true

9