go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:1990014
1,990,014
orthogonal array
cellular_component
Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels).
[ "NIF_Subcellular:sao1747012216", "PMID:22718347" ]
null
[ "OAP", "orthogonal array of particles", "square array" ]
[ "RELATED", "EXACT", "RELATED" ]
[]
[]
[ "NIF_Subcellular:sao1747012216" ]
[ "GO:0110165" ]
[ "part_of GO:0005886" ]
[ "part_of" ]
[ "GO:0005886" ]
[ "GO:0005886", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2012-12-13T20:14:15Z
false
true
7
GO:1990015
1,990,015
ensheathing process
cellular_component
A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma.
[ "NIF_Subcellular:sao1376748732" ]
null
[ "ensheathing process of Schwann cell" ]
[ "NARROW" ]
[]
[]
[ "NIF_Subcellular:sao1376748732" ]
[ "GO:0110165" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2012-12-19T09:42:15Z
false
true
3
GO:1990016
1,990,016
neck portion of tanycyte
cellular_component
Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.
[ "ISBN:0195065719", "NIF_Subcellular:sao901230115" ]
null
[ "neck portion" ]
[ "BROAD" ]
[]
[]
[ "NIF_Subcellular:sao901230115" ]
[ "GO:0110165" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2012-12-19T15:17:17Z
false
true
7
GO:1990017
1,990,017
somatic portion of tanycyte
cellular_component
Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.
[ "ISBN:0195065719", "NIF_Subcellular:sao401910342" ]
null
[ "somatic portion" ]
[ "BROAD" ]
[]
[]
[ "NIF_Subcellular:sao401910342" ]
[ "GO:0044297" ]
[]
[]
[]
[ "GO:0044297" ]
[]
[]
[]
[]
[]
[]
pr
2012-12-19T15:19:25Z
false
true
1
GO:1990018
1,990,018
tail portion of tanycyte
cellular_component
Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell.
[ "ISBN:0195065719", "NIF_Subcellular:sao1749953771" ]
null
[ "tail portion" ]
[ "BROAD" ]
[]
[]
[ "NIF_Subcellular:sao1749953771" ]
[ "GO:0110165" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2012-12-19T15:21:20Z
false
true
2
GO:1990019
1,990,019
protein storage vacuole organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole.
[ "GOC:tb", "PMID:21670741" ]
null
[]
[]
[]
[]
[]
[ "GO:0007033" ]
[]
[]
[]
[ "GO:0007033" ]
[]
[]
[]
[]
[]
[]
tb
2012-12-20T21:00:09Z
false
true
5
GO:1990020
1,990,020
recurrent axon collateral
cellular_component
Axon collateral that ramifies in the area of the soma of the cell of origin.
[ "NIF_Subcellular:sao1642494436" ]
null
[ "recurrent collateral" ]
[ "BROAD" ]
[]
[]
[ "NIF_Subcellular:sao1642494436" ]
[ "GO:0044303" ]
[]
[]
[]
[ "GO:0044303" ]
[]
[]
[]
[]
[]
[]
pr
2013-01-10T16:04:31Z
false
true
6
GO:1990021
1,990,021
Schaffer axon collateral
cellular_component
Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1.
[ "NIF_Subcellular:nlx_subcell_20090511" ]
null
[ "Schaffer collateral" ]
[ "BROAD" ]
[]
[]
[ "NIF_Subcellular:nlx_subcell_20090511" ]
[ "GO:0044303" ]
[]
[]
[]
[ "GO:0044303" ]
[]
[]
[]
[]
[]
[]
pr
2013-01-10T16:06:17Z
false
true
6
GO:1990022
1,990,022
obsolete RNA polymerase III complex import into nucleus
biological_process
OBSOLETE. The directed movement of an RNA polymerase III complex from the cytoplasm to the nucleus.
[ "GOC:mcc", "PMID:23267056" ]
The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.
[ "DNA-directed RNA polymerase III complex import into nucleus", "DNA-directed RNA polymerase III complex localization to nucleus", "RNA polymerase III complex import into nucleus", "RNA polymerase III complex localisation to nucleus", "RNA polymerase III complex localization to nucleus" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006606" ]
[]
pr
2013-01-15T12:46:26Z
true
true
8
GO:1990023
1,990,023
mitotic spindle midzone
cellular_component
The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
[ "GOC:mtg_cell_cycle", "GOC:vw" ]
null
[]
[]
[]
[]
[]
[ "GO:0051233" ]
[ "part_of GO:0072686" ]
[ "part_of" ]
[ "GO:0072686" ]
[ "GO:0051233", "GO:0072686" ]
[]
[]
[]
[]
[]
[]
vw
2013-02-05T15:41:48Z
false
true
2
GO:1990025
1,990,025
F bouton
cellular_component
Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles.
[ "NIF_Subcellular:nlx_subcell_100206" ]
null
[]
[]
[]
[]
[ "NIF_Subcellular:nlx_subcell_100206" ]
[ "GO:0043195" ]
[]
[]
[]
[ "GO:0043195" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-06T10:29:42Z
false
true
8
GO:1990026
1,990,026
hippocampal mossy fiber expansion
cellular_component
Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites.
[ "NIF_Subcellular:nlx_subcell_1005002" ]
null
[ "dentate gyrus granule cell axonal bouton", "dentate gyrus mossy fiber expansion", "mossy fiber expansion" ]
[ "RELATED", "RELATED", "BROAD" ]
[]
[]
[ "NIF_Subcellular:nlx_subcell_1005002" ]
[ "GO:0043195" ]
[ "part_of GO:0097457" ]
[ "part_of" ]
[ "GO:0097457" ]
[ "GO:0043195", "GO:0097457" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-06T10:31:59Z
false
true
8
GO:1990028
1,990,028
intermediate voltage-gated calcium channel activity
molecular_function
Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded.
[ "GOC:BHF", "GOC:rl", "PMID:16382099", "Wikipedia:Calcium_channel" ]
null
[ "R-type calcium channel" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0005245" ]
[]
[]
[]
[ "GO:0005245" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-06T20:55:41Z
false
true
1
GO:1990029
1,990,029
vasomotion
biological_process
The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm.
[ "GOC:sl", "PMID:14993429", "PMID:15678091", "PMID:1932763" ]
null
[]
[]
[]
[]
[]
[ "GO:0003013" ]
[]
[]
[]
[ "GO:0003013" ]
[]
[]
[]
[]
[]
[]
tb
2013-02-06T22:30:21Z
false
true
7
GO:1990030
1,990,030
pericellular basket
cellular_component
Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name.
[ "NIF_Subcellular:sao413722576" ]
null
[ "peri cellular basket", "peri-cellular basket" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "NIF_Subcellular:sao413722576" ]
[ "GO:0110165" ]
[ "part_of GO:0030424" ]
[ "part_of" ]
[ "GO:0030424" ]
[ "GO:0030424", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-07T12:53:54Z
false
true
4
GO:1990031
1,990,031
pinceau fiber
cellular_component
Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment.
[ "NIF_Subcellular:sao109906988" ]
null
[]
[]
[]
[]
[ "NIF_Subcellular:sao109906988" ]
[ "GO:0110165" ]
[ "part_of GO:0030424" ]
[ "part_of" ]
[ "GO:0030424" ]
[ "GO:0030424", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-07T12:56:50Z
false
true
4
GO:1990032
1,990,032
parallel fiber
cellular_component
A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium.
[ "ISBN:0195159551", "NIF_Subcellular:nlx_330" ]
null
[]
[]
[]
[]
[ "NIF_Subcellular:nlx_330" ]
[ "GO:0030424" ]
[]
[]
[]
[ "GO:0030424" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-07T12:58:43Z
false
true
1
GO:1990033
1,990,033
dendritic branch point
cellular_component
The part of a dendritic tree where it branches, giving rise to a dendritic branch.
[ "GOC:aruk", "GOC:bc", "NIF_Subcellular:sao1348591767" ]
null
[ "branch point of dendrite" ]
[ "EXACT" ]
[]
[]
[ "NIF_Subcellular:sao1348591767" ]
[ "GO:0061845" ]
[ "part_of GO:0097447" ]
[ "part_of" ]
[ "GO:0097447" ]
[ "GO:0061845", "GO:0097447" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-07T13:01:01Z
false
true
8
GO:1990034
1,990,034
calcium ion export across plasma membrane
biological_process
The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region.
[ "GOC:mah", "PMID:2145281" ]
null
[ "calcium ion efflux from cell", "calcium ion export from cell" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0070588", "GO:0140115" ]
[]
[]
[]
[ "GO:0070588", "GO:0140115" ]
[]
[]
[]
[]
[]
[]
mah
2013-02-07T13:01:29Z
false
true
7
GO:1990036
1,990,036
calcium ion import into sarcoplasmic reticulum
biological_process
The directed movement of calcium ions into a sarcoplasmic reticulum.
[ "GOC:BHF", "PMID:17286271" ]
null
[]
[]
[]
[]
[]
[ "GO:0046907", "GO:0070296" ]
[ "occurs_in GO:0005737" ]
[ "occurs_in" ]
[ "GO:0005737" ]
[ "GO:0005737", "GO:0046907", "GO:0070296" ]
[]
[]
[]
[]
[]
[]
tb
2013-02-07T23:22:27Z
false
true
7
GO:1990037
1,990,037
Lewy body core
cellular_component
The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments.
[ "NIF_Subcellular:sao6587439252" ]
null
[]
[]
[]
[]
[ "NIF_Subcellular:sao6587439252" ]
[ "GO:0110165" ]
[ "part_of GO:0097413" ]
[ "part_of" ]
[ "GO:0097413" ]
[ "GO:0097413", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-08T12:56:59Z
false
true
8
GO:1990038
1,990,038
Lewy body corona
cellular_component
The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.
[ "NIF_Subcellular:sao5764355747" ]
null
[ "halo" ]
[ "BROAD" ]
[]
[]
[ "NIF_Subcellular:sao5764355747" ]
[ "GO:0110165" ]
[ "part_of GO:0097413" ]
[ "part_of" ]
[ "GO:0097413" ]
[ "GO:0097413", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-08T13:03:27Z
false
true
5
GO:1990039
1,990,039
hypolemmal cisterna
cellular_component
Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer.
[ "ISBN:0195065719", "NIF_Subcellular:sao1634374950" ]
null
[ "hypolemmal cisternae" ]
[ "EXACT" ]
[]
[]
[ "NIF_Subcellular:sao1634374950" ]
[ "GO:0120082" ]
[]
[]
[]
[ "GO:0120082" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13848\" xsd:anyURI" ]
pr
2013-02-11T15:04:56Z
false
true
9
GO:1990040
1,990,040
sub-surface cisterna
cellular_component
Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane.
[ "ISBN:0195065719", "NIF_Subcellular:sao128470897" ]
null
[ "sub-surface cisternae" ]
[ "EXACT" ]
[]
[]
[ "NIF_Subcellular:sao128470897" ]
[ "GO:1990039" ]
[]
[]
[]
[ "GO:1990039" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-11T15:10:47Z
false
true
4
GO:1990042
1,990,042
obsolete glycerol dehydrogenase [NAD(P)+] activity
molecular_function
OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced.
[ "PMID:22979944" ]
This term was obsoleted because it is an unnecessary grouping term.
[ "glycerol dehydrogenase activity, NAD or NADP as acceptor" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0008888", "GO:0047956" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30105\" xsd:anyURI" ]
rb
2013-02-14T00:34:45Z
true
true
7
GO:1990043
1,990,043
obsolete 5' deoxyribonuclease (pyrimidine dimer) activity
molecular_function
OBSOLETE. Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate.
[ "GOC:al", "PMID:9708997" ]
The reason for obsoletion is that this term is not different from the parent term deoxyribonuclease (pyrimidine dimer) activity.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0033892" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28395\" xsd:anyURI" ]
pr
2013-02-15T12:16:51Z
true
true
8
GO:1990044
1,990,044
protein localization to lipid droplet
biological_process
A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet.
[ "GOC:sart", "PMID:22505614" ]
null
[ "protein localisation to adiposome", "protein localisation to lipid body", "protein localisation to lipid droplet", "protein localisation to lipid particle", "protein localization to adiposome", "protein localization to lipid body", "protein localization to lipid particle" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0033365" ]
[]
[]
[]
[ "GO:0033365" ]
[]
[]
[]
[]
[]
[]
sart
2013-02-15T12:40:57Z
false
true
8
GO:1990046
1,990,046
stress-induced mitochondrial fusion
biological_process
Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.
[ "GOC:lb", "PMID:19360003" ]
null
[ "mitochondrial fusion in response to stress", "SIMH", "stress-induced mitochondrial hyperfusion" ]
[ "RELATED", "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0008053", "GO:0033554" ]
[]
[]
[]
[ "GO:0008053", "GO:0033554" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-15T16:01:55Z
false
true
3
GO:1990047
1,990,047
spindle matrix
cellular_component
A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis.
[ "GOC:ans", "PMID:19273613", "PMID:22855526" ]
null
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005856" ]
[ "part_of" ]
[ "GO:0005856" ]
[ "GO:0005856", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-18T08:51:47Z
false
true
1
GO:1990048
1,990,048
anterograde neuronal dense core vesicle transport
biological_process
The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.
[ "GOC:kmv", "PMID:23358451" ]
null
[ "anterograde dense core granule trafficking", "anterograde dense core granule transport" ]
[ "EXACT", "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0008089", "GO:0047496", "GO:0099519" ]
[]
[]
[]
[ "GO:0008089", "GO:0047496", "GO:0099519" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:1990049
1,990,049
retrograde neuronal dense core vesicle transport
biological_process
The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.
[ "GOC:kmv", "PMID:23358451", "PMID:24762653" ]
null
[ "retrograde dense core granule trafficking", "retrograde dense core granule transport" ]
[ "EXACT", "EXACT" ]
[]
[ "goslim_synapse" ]
[]
[ "GO:0008090", "GO:0047496", "GO:0099519" ]
[]
[]
[]
[ "GO:0008090", "GO:0047496", "GO:0099519" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-19T13:31:44Z
false
true
3
GO:1990050
1,990,050
phosphatidic acid transfer activity
molecular_function
Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-...
[ "PMID:23042293" ]
null
[ "intermembrane PA transfer activity", "intermembrane phosphatidic acid transfer activity", "phosphatidic acid carrier activity", "phosphatidic acid transporter activity" ]
[ "EXACT", "NARROW", "EXACT", "BROAD" ]
[]
[]
[]
[ "GO:0120014" ]
[]
[]
[]
[ "GO:0120014" ]
[]
[]
[]
[]
[]
[]
rb
2013-02-21T00:45:28Z
false
true
1
GO:1990051
1,990,051
activation of protein kinase C activity
biological_process
Any process that initiates the activity of the inactive enzyme protein kinase C.
[ "PMID:3156004" ]
null
[ "PKC activation", "protein kinase C activation" ]
[ "EXACT", "EXACT" ]
[]
[ "gocheck_obsoletion_candidate" ]
[]
[ "GO:0032147" ]
[]
[]
[]
[ "GO:0032147" ]
[]
[]
[]
[]
[]
[]
sl
2013-02-21T19:57:54Z
false
true
6
GO:1990052
1,990,052
ER to chloroplast lipid transport
biological_process
The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast.
[ "PMID:18689504" ]
null
[ "endoplasmic reticulum to chloroplast lipid transport", "ER to chloroplast lipid trafficking" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032365", "GO:1901965" ]
[]
[]
[]
[ "GO:0032365", "GO:1901965" ]
[]
[]
[]
[]
[]
[]
tb
2013-02-22T00:05:23Z
false
true
2
GO:1990054
1,990,054
response to temozolomide
biological_process
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.
[ "GOC:hp" ]
Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
[]
[]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:1901698", "GO:1901700" ]
[]
[]
[]
[ "GO:1901698", "GO:1901700" ]
[]
[]
[]
[]
[]
[]
pr
2013-02-22T10:09:44Z
false
true
9
GO:1990055
1,990,055
phenylacetaldehyde synthase activity
molecular_function
Catalyzes the reaction: L-phenylalanine + O2 + H2O + H+ = 2-phenylacetaldehyde + H2O2 + NH4+ + CO2.
[ "PMID:16766535", "PMID:23204519", "RHEA:55532" ]
null
[ "aromatic aldehyde synthase" ]
[ "BROAD" ]
[]
[]
[ "EC:4.1.1.109", "MetaCyc:RXN-8990", "RHEA:55532" ]
[ "GO:0016831" ]
[]
[]
[]
[ "GO:0016831" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:4.1.1.109", "skos:exactMatch RHEA:55532", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28523\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-onto...
tb
2013-02-25T20:22:35Z
false
true
4
GO:1990056
1,990,056
obsolete protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process
molecular_function
OBSOLETE. Catalysis of the phosphorylation of an amino acid residue in a substrate protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP, thereby targeting the substrate to the proteasomal ubiquitin mediated protein catabolic process.
[ "PMID:21098119", "PMID:21993622", "PMID:23264631" ]
This term was obsoleted at the TermGenie Gatekeeper stage.
[ "protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
rb
2013-02-26T21:28:08Z
true
true
6
GO:1990057
1,990,057
obsolete cell cycle arrest in response to DNA damage stimulus
biological_process
OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of DNA damage from environmental insults or errors during metabolism.
[ "GOC:rph", "PMID:10630641" ]
This term was obsoleted at the TermGenie Gatekeeper stage.
[ "cell cycle arrest in response to DNA damage stimulus" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
rph
2013-03-06T13:48:44Z
true
true
9
GO:1990058
1,990,058
fruit replum development
biological_process
The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum.
[ "PMID:23133401", "PO:0025267" ]
null
[]
[]
[]
[]
[]
[ "GO:0009791", "GO:0048856" ]
[ "part_of GO:0010154" ]
[ "part_of" ]
[ "GO:0010154" ]
[ "GO:0009791", "GO:0010154", "GO:0048856" ]
[]
[]
[]
[]
[]
[]
dhl
2013-03-12T21:15:15Z
false
true
5
GO:1990059
1,990,059
fruit valve development
biological_process
The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces.
[ "PMID:23133401", "PO:0000033" ]
null
[]
[]
[]
[]
[]
[ "GO:0009791", "GO:0048856" ]
[ "part_of GO:0010154" ]
[ "part_of" ]
[ "GO:0010154" ]
[ "GO:0009791", "GO:0010154", "GO:0048856" ]
[]
[]
[]
[]
[]
[]
dhl
2013-03-12T21:21:15Z
false
true
4
GO:1990060
1,990,060
maltose transport complex
cellular_component
Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cass...
[ "PMID:18033289" ]
null
[ "maltose ABC transporter complex", "maltose ATP-binding cassette transporter complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043190" ]
[]
[]
[]
[ "GO:0043190" ]
[]
[]
[]
[]
[]
[]
jl
2013-03-13T13:52:48Z
false
true
3
GO:1990061
1,990,061
bacterial degradosome
cellular_component
The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase.
[ "GOC:bhm", "PMID:21805185" ]
null
[]
[]
[]
[]
[]
[ "GO:0000177" ]
[ "part_of GO:0005829" ]
[ "part_of" ]
[ "GO:0005829" ]
[ "GO:0000177", "GO:0005829" ]
[]
[]
[]
[]
[]
[]
bhm
2013-03-20T13:51:49Z
false
true
4
GO:1990063
1,990,063
Bam protein complex
cellular_component
Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex.
[ "GOC:bhm", "PMID:20378773" ]
null
[ "OMP complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0098796", "GO:0140392" ]
[ "part_of GO:0031241" ]
[ "part_of" ]
[ "GO:0031241" ]
[ "GO:0031241", "GO:0098796", "GO:0140392" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31720\" xsd:anyURI" ]
bhm
2013-03-20T15:42:57Z
false
true
1
GO:1990064
1,990,064
ground tissue pattern formation
biological_process
The regionalization process that gives rise to the patterning of the ground tissue.
[ "PMID:23444357" ]
null
[ "ground tissue patterning" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0003002" ]
[]
[]
[]
[ "GO:0003002" ]
[]
[]
[]
[]
[]
[]
tb
2013-03-21T23:24:44Z
false
true
3
GO:1990065
1,990,065
Dxr protein complex
cellular_component
A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
[ "GOC:bhm", "PMID:15339150" ]
null
[ "1-deoxy-D-xylulose 5-phosphate reductoisomerase complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
bhm
2013-03-27T16:58:54Z
false
true
3
GO:1990066
1,990,066
energy quenching
biological_process
The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence.
[ "PMID:10938857" ]
null
[]
[]
[]
[]
[]
[ "GO:0009416" ]
[]
[]
[]
[ "GO:0009416" ]
[]
[]
[]
[]
[]
[]
tb
2013-03-27T21:02:00Z
false
true
5
GO:1990067
1,990,067
intrachromosomal DNA recombination
biological_process
The process of DNA recombination occurring within a single chromosome.
[ "PMID:7748165" ]
null
[ "intrastrand DNA recombination" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006310" ]
[]
[]
[]
[ "GO:0006310" ]
[]
[]
[]
[]
[]
[]
tb
2013-03-27T21:11:35Z
false
true
6
GO:1990068
1,990,068
seed dehydration
biological_process
The seed development process whose outcome is the drying of a maturing seed.
[ "PMID:20138563" ]
null
[]
[]
[]
[]
[]
[ "GO:0048609" ]
[ "part_of GO:0010431" ]
[ "part_of" ]
[ "GO:0010431" ]
[ "GO:0010431", "GO:0048609" ]
[]
[]
[]
[]
[]
[]
tb
2013-03-27T21:16:03Z
false
true
3
GO:1990069
1,990,069
stomatal opening
biological_process
The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
[ "PMID:21749899" ]
null
[]
[]
[]
[]
[]
[ "GO:0010118" ]
[]
[]
[]
[ "GO:0010118" ]
[]
[]
[]
[]
[]
[]
tb
2013-03-27T21:18:48Z
false
true
9
GO:1990070
1,990,070
TRAPPI protein complex
cellular_component
A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as th...
[ "GOC:bhm", "PMID:20375281", "PMID:22669257" ]
null
[ "TRAPP core complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030008" ]
[ "part_of GO:0005793" ]
[ "part_of" ]
[ "GO:0005793" ]
[ "GO:0005793", "GO:0030008" ]
[]
[]
[]
[]
[]
[]
bhm
2013-03-28T14:04:40Z
false
true
1
GO:1990071
1,990,071
TRAPPII protein complex
cellular_component
A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs6...
[ "GOC:bhm", "PMID:20375281", "PMID:22669257" ]
null
[]
[]
[]
[]
[]
[ "GO:0030008" ]
[ "part_of GO:0005768", "part_of GO:0005794" ]
[ "part_of", "part_of" ]
[ "GO:0005768", "GO:0005794" ]
[ "GO:0005768", "GO:0005794", "GO:0030008" ]
[]
[]
[]
[]
[]
[]
bhm
2013-03-28T14:24:08Z
false
true
2
GO:1990072
1,990,072
TRAPPIII protein complex
cellular_component
A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins.
[ "GOC:bhm", "PMID:20375281", "PMID:22669257" ]
null
[]
[]
[]
[]
[]
[ "GO:0030008" ]
[ "part_of GO:0005794" ]
[ "part_of" ]
[ "GO:0005794" ]
[ "GO:0005794", "GO:0030008" ]
[]
[]
[]
[]
[]
[]
bhm
2013-03-28T14:28:59Z
false
true
1
GO:1990073
1,990,073
perforation plate
cellular_component
A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).
[ "GOC:PO_curators", "ISBN:0471245194" ]
Part of a vessel member (PO:0002003). May be simple, with one perforation, or multiperforate, with more than one perforation. Perforation plates are usually on the end walls of a cell, but may also be on the side walls.
[]
[]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005618" ]
[ "part_of" ]
[ "GO:0005618" ]
[ "GO:0005618", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
tb
2013-03-29T00:53:28Z
false
true
3
GO:1990074
1,990,074
polyuridylation-dependent mRNA catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.
[ "GOC:vw", "PMID:23503588" ]
null
[]
[]
[]
[]
[]
[ "GO:0006402", "GO:0043632", "GO:0061157" ]
[]
[]
[]
[ "GO:0006402", "GO:0043632", "GO:0061157" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20568\" xsd:anyURI" ]
tb
2013-04-16T22:51:46Z
false
true
4
GO:1990075
1,990,075
periciliary membrane compartment
cellular_component
A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis.
[ "GOC:cilia", "GOC:dr", "GOC:krc", "PMID:22342749" ]
null
[ "PCMC" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0098590" ]
[]
[]
[]
[ "GO:0098590" ]
[]
[]
[]
[]
[]
[]
pr
2013-04-24T10:14:50Z
false
true
4
GO:1990076
1,990,076
obsolete cell wall polysaccharide catabolic process involved in abscission
biological_process
OBSOLETE. Any cell wall polysaccharide catabolic process that is involved in abscission.
[ "GOC:TermGenie", "PMID:23479623" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0009838", "GO:0044347" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31254\" xsd:anyURI" ]
dhl
2013-04-25T16:29:43Z
true
true
8
GO:1990077
1,990,077
primosome complex
cellular_component
Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the...
[ "GOC:bhm", "GOC:mah", "PMID:21856207" ]
null
[ "primosome" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032993" ]
[ "part_of GO:0030894" ]
[ "part_of" ]
[ "GO:0030894" ]
[ "GO:0030894", "GO:0032993" ]
[]
[]
[]
[]
[]
[]
bhm
2013-04-26T11:55:28Z
false
true
9
GO:1990078
1,990,078
replication inhibiting complex
cellular_component
A protein complex that inhibits multiple events of replication initiation during one replication cycle.
[ "GOC:bhm", "PMID:21708944" ]
null
[]
[]
[]
[]
[]
[ "GO:0032991" ]
[ "part_of GO:0030894" ]
[ "part_of" ]
[ "GO:0030894" ]
[ "GO:0030894", "GO:0032991" ]
[]
[]
[]
[]
[]
[]
bhm
2013-04-26T13:07:03Z
false
true
9
GO:1990079
1,990,079
cartilage homeostasis
biological_process
A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function.
[ "GOC:hjd", "PMID:21652695" ]
null
[ "negative regulation of cartilage homeostasis", "positive regulation of cartilage homeostasis", "regulation of cartilage homeostasis" ]
[ "RELATED", "RELATED", "RELATED" ]
[ "GO:1902094", "GO:1902095", "GO:1902096" ]
[]
[]
[ "GO:0001894" ]
[]
[]
[]
[ "GO:0001894" ]
[]
[]
[]
[]
[]
[]
hjd
2013-04-29T20:10:15Z
false
true
9
GO:1990080
1,990,080
2-phenylethylamine receptor activity
molecular_function
Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity.
[ "PMID:16878137" ]
null
[ "beta-phenylethylamine receptor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008227" ]
[]
[]
[]
[ "GO:0008227" ]
[]
[]
[]
[]
[]
[]
sp
2013-04-30T10:53:19Z
false
true
9
GO:1990081
1,990,081
trimethylamine receptor activity
molecular_function
Combining with the biogenic amine trimethylamine to initiate a change in cell activity.
[ "PMID:16878137" ]
null
[]
[]
[]
[]
[]
[ "GO:0001594" ]
[]
[]
[]
[ "GO:0001594" ]
[]
[]
[]
[]
[]
[]
sp
2013-04-30T10:57:07Z
false
true
1
GO:1990082
1,990,082
DnaA-L2 complex
cellular_component
A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2.
[ "GOC:bhm", "PMID:21288885" ]
null
[]
[]
[]
[]
[]
[ "GO:1990078" ]
[]
[]
[]
[ "GO:1990078" ]
[]
[]
[]
[]
[]
[]
bhm
2013-04-30T11:46:41Z
false
true
3
GO:1990083
1,990,083
DnaA-Hda complex
cellular_component
A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda.
[ "GOC:bhm", "PMID:21708944" ]
null
[]
[]
[]
[]
[]
[ "GO:1990078" ]
[]
[]
[]
[ "GO:1990078" ]
[]
[]
[]
[]
[]
[]
bhm
2013-04-30T11:49:04Z
false
true
9
GO:1990084
1,990,084
DnaA-Dps complex
cellular_component
A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps.
[ "GOC:bhm", "PMID:18284581" ]
null
[]
[]
[]
[]
[]
[ "GO:1990078" ]
[]
[]
[]
[ "GO:1990078" ]
[]
[]
[]
[]
[]
[]
bhm
2013-04-30T11:50:17Z
false
true
9
GO:1990085
1,990,085
Hda-beta clamp complex
cellular_component
A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda.
[ "GOC:bhm", "PMID:15150238" ]
null
[ "Hda-DnaN complex", "Hda-dpo3b complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990078" ]
[]
[]
[]
[ "GO:1990078" ]
[]
[]
[]
[]
[]
[]
bhm
2013-04-30T11:53:18Z
false
true
8
GO:1990086
1,990,086
lens fiber cell apoptotic process
biological_process
Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
[ "CL:0011004", "GOC:hjd", "PMID:11095619" ]
null
[]
[]
[]
[]
[]
[ "GO:1904019" ]
[]
[]
[]
[ "GO:1904019" ]
[]
[]
[]
[]
[]
[]
hjd
2013-05-01T19:09:28Z
false
true
9
GO:1990088
1,990,088
[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity
molecular_function
Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-coenzyme M + a [Co(I) methanol-specific corrinoid protein] + H+.
[ "PMID:10077852", "RHEA:45208" ]
This function is the second step in the pathway of methanogenesis from methanol.
[ "methanol-specific methylcobalamin: coenzyme M methyltransferase activity", "methanol-specific methylcobalamin:coenzyme M methyltransferase activity", "methanol-specific methylcobalamin:CoM methyltransferase activity", "methylcobamide:coenzyme M methyltransferase activity", "methylcobamide:CoM methyltransfe...
[ "EXACT", "EXACT", "EXACT", "BROAD", "BROAD" ]
[ "GO:0043851" ]
[]
[ "EC:2.1.1.246", "MetaCyc:RXN-8096", "RHEA:45208" ]
[ "GO:0008168" ]
[]
[]
[]
[ "GO:0008168" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.1.1.246", "skos:exactMatch RHEA:45208", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/18530\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
hjd
2013-05-06T15:07:20Z
false
true
1
GO:1990089
1,990,089
response to nerve growth factor
biological_process
A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
[ "PMID:22399805" ]
null
[ "response to nerve growth factor stimulus" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0070848" ]
[]
[]
[]
[ "GO:0070848" ]
[]
[]
[]
[]
[]
[]
sl
2013-05-06T17:08:47Z
false
true
1
GO:1990090
1,990,090
cellular response to nerve growth factor stimulus
biological_process
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
[ "PMID:22399805", "Wikipedia:Nerve_growth_factor" ]
null
[ "cellular response to NGF" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0071363", "GO:1990089" ]
[]
[]
[]
[ "GO:0071363", "GO:1990089" ]
[]
[]
[]
[]
[]
[]
sl
2013-05-06T17:13:36Z
false
true
9
GO:1990091
1,990,091
sodium-dependent self proteolysis
biological_process
The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
[ "PMID:20460380" ]
null
[]
[]
[]
[]
[]
[ "GO:0097264" ]
[]
[]
[]
[ "GO:0097264" ]
[]
[]
[]
[]
[]
[]
sl
2013-05-06T17:30:23Z
false
true
2
GO:1990092
1,990,092
calcium-dependent self proteolysis
biological_process
The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
[ "PMID:20460380" ]
null
[]
[]
[]
[]
[]
[ "GO:0097264" ]
[]
[]
[]
[ "GO:0097264" ]
[]
[]
[]
[]
[]
[]
sl
2013-05-06T17:33:34Z
false
true
8
GO:1990093
1,990,093
obsolete negative regulation of N-methyl-D-aspartate receptor clustering
biological_process
OBSOLETE. The negative regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
[ "PMID:18442977" ]
This term was obsoleted at the TermGenie Gatekeeper stage.
[ "negative regulation of N-methyl-D-aspartate receptor clustering", "negative regulation of NMDA receptor clustering" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
sl
2013-05-06T17:39:44Z
true
true
1
GO:1990094
1,990,094
obsolete positive regulation of N-methyl-D-aspartate receptor clustering
biological_process
OBSOLETE. The positive regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
[ "PMID:18442977" ]
This term was obsoleted at the TermGenie Gatekeeper stage.
[ "positive regulation of N-methyl-D-aspartate receptor clustering", "positive regulation of NMDA receptor clustering" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
sl
2013-05-06T17:44:00Z
true
true
7
GO:1990095
1,990,095
obsolete positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species
biological_process
OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
[ "GOC:kmv", "PMID:16166371" ]
This term was obsoleted because it represents a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0034599", "GO:0045944" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12739\" xsd:anyURI" ]
pr
2013-05-07T12:10:32Z
true
true
6
GO:1990096
1,990,096
obsolete positive regulation of transcription from RNA polymerase II promoter in response to superoxide
biological_process
OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
[ "GOC:kmv", "PMID:12869585", "PMID:16166371" ]
This term was obsoleted because it represents a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0034599", "GO:0045944" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12739\" xsd:anyURI" ]
pr
2013-05-07T12:25:34Z
true
true
3
GO:1990097
1,990,097
SeqA-DNA complex
cellular_component
A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of r...
[ "GOC:bhm", "PMID:12379844", "PMID:15933720", "PMID:23149570" ]
null
[ "SeqA-dsDNA complex", "SeqA-hemimethylated DNA complex", "SeqA-hemimethylation dsDNA complex" ]
[ "NARROW", "NARROW", "NARROW" ]
[]
[]
[]
[ "GO:0032993" ]
[]
[]
[]
[ "GO:0032993" ]
[]
[]
[]
[]
[]
[]
bhm
2013-05-13T11:18:11Z
false
true
7
GO:1990098
1,990,098
core primosome complex
cellular_component
A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication.
[ "GOC:bhm", "PMID:21856207" ]
The core primosome refers to a helicase-primase complex, and should not be confused with the more general GO term 'primosome complex ; GO:1990077'.
[ "core primosome" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:1990077" ]
[]
[]
[]
[ "GO:1990077" ]
[]
[]
[]
[]
[]
[]
bhm
2013-05-14T10:30:02Z
false
true
9
GO:1990099
1,990,099
pre-primosome complex
cellular_component
Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pr...
[ "GOC:bhm", "PMID:18179598", "PMID:20129058", "PMID:8663105" ]
null
[ "pre-priming complex", "pre-primosome", "pre-replication complex", "preprimosome", "preprimosome complex", "prereplication complex" ]
[ "EXACT", "EXACT", "RELATED", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990077" ]
[]
[]
[]
[ "GO:1990077" ]
[]
[]
[]
[]
[]
[]
bhm
2013-05-14T10:53:42Z
false
true
5
GO:1990100
1,990,100
DnaB-DnaC complex
cellular_component
A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC).
[ "GOC:bhm", "PMID:20129058" ]
DnaB and DnaC may be present in different ratios in different forms of the DnaB-DnaC complex, including a DnaB6-DnaC3 complex active at the oriC, and a DnaB6-DnaC6 complex.
[ "DnaB6-DnaC3 complex", "DnaB6-DnaC6 complex", "helicase-loading complex" ]
[ "NARROW", "NARROW", "BROAD" ]
[]
[]
[]
[ "GO:0032991" ]
[ "has_part GO:1990161", "part_of GO:1990077" ]
[ "has_part", "part_of" ]
[ "GO:1990161", "GO:1990077" ]
[ "GO:0032991", "GO:1990077", "GO:1990161" ]
[]
[]
[]
[]
[]
[]
bhm
2013-05-14T12:02:22Z
false
true
1
GO:1990101
1,990,101
DnaA-oriC complex
cellular_component
A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle.
[ "GOC:bhm", "PMID:19833870" ]
null
[ "DnaA-DNA complex" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:1990077" ]
[]
[]
[]
[ "GO:1990077" ]
[]
[]
[]
[]
[]
[]
bhm
2013-05-14T12:07:04Z
false
true
6
GO:1990102
1,990,102
DnaA-DiaA complex
cellular_component
A protein-DNA complex containing a tetramer of DiaA attached to multiple DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA...
[ "GOC:bhm", "PMID:15326179", "PMID:17699754" ]
null
[ "DnaA-DiaA-DNA complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:1990077" ]
[ "has_part GO:1990101", "has_part GO:1990125" ]
[ "has_part", "has_part" ]
[ "GO:1990101", "GO:1990125" ]
[ "GO:1990077", "GO:1990101", "GO:1990125" ]
[]
[]
[]
[]
[]
[]
bhm
2013-05-14T12:33:59Z
false
true
3
GO:1990103
1,990,103
DnaA-HU complex
cellular_component
A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC.
[ "GOC:bhm", "PMID:18179598" ]
null
[ "DnaA-HU-DNA complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:1990077" ]
[]
[]
[]
[ "GO:1990077" ]
[]
[]
[]
[]
[]
[]
bhm
2013-05-14T12:36:39Z
false
true
4
GO:1990104
1,990,104
DNA bending complex
cellular_component
A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction.
[ "GOC:bhm", "PMID:17097674" ]
null
[ "histone-like DNA binding complex" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
bhm
2013-05-20T09:29:06Z
false
true
6
GO:1990105
1,990,105
obsolete regulation of voltage-gated potassium channel activity
biological_process
OBSOLETE. Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity.
[ "PMID:19219384" ]
This term was obsoleted at the TermGenie Gatekeeper stage.
[ "regulation of voltage-gated potassium channel activity" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
sl
2013-05-21T15:12:06Z
true
true
6
GO:1990107
1,990,107
thiazole synthase activity
molecular_function
Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H+ + 2 H2O.
[ "PMID:22031445", "RHEA:26297" ]
Part of the pathway for thiamine biosynthesis.
[ "1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity" ]
[ "EXACT" ]
[]
[]
[ "EC:2.8.1.10", "RHEA:26297" ]
[ "GO:0016783" ]
[ "part_of GO:0009228" ]
[ "part_of" ]
[ "GO:0009228" ]
[ "GO:0009228", "GO:0016783" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.8.1.10", "skos:exactMatch RHEA:26297", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28942\" xsd:anyURI" ]
pr
2013-05-28T12:36:04Z
false
true
6
GO:1990108
1,990,108
protein linear deubiquitination
biological_process
A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein.
[ "PMID:23708998" ]
null
[]
[]
[]
[]
[]
[ "GO:0016579" ]
[]
[]
[]
[ "GO:0016579" ]
[]
[]
[]
[]
[]
[]
sp
2013-05-29T05:58:49Z
false
true
8
GO:1990110
1,990,110
callus formation
biological_process
The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.
[ "ISBN:0070187517" ]
null
[]
[]
[]
[]
[]
[ "GO:0032501" ]
[ "part_of GO:0042060" ]
[ "part_of" ]
[ "GO:0042060" ]
[ "GO:0032501", "GO:0042060" ]
[]
[]
[]
[]
[]
[]
tb
2013-05-29T22:02:52Z
false
true
4
GO:1990111
1,990,111
spermatoproteasome complex
cellular_component
A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific...
[ "GOC:sp", "PMID:23706739" ]
null
[]
[]
[]
[]
[]
[ "GO:0000502" ]
[]
[]
[]
[ "GO:0000502" ]
[]
[]
[]
[]
[]
[]
sp
2013-05-31T11:56:52Z
false
true
6
GO:1990112
1,990,112
RQC complex
cellular_component
A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
[ "GOC:rb", "PMID:23178123", "PMID:23232563" ]
null
[ "ribosome quality control complex", "ribosome-bound quality control complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
rb
2013-05-31T21:42:43Z
false
true
6
GO:1990113
1,990,113
RNA polymerase I assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex.
[ "GOC:rb", "PMID:23459708" ]
null
[ "DNA-directed RNA polymerase I complex assembly", "RNA Polymerase I complex assembly" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[]
[]
[]
rb
2013-05-31T21:44:41Z
false
true
3
GO:1990114
1,990,114
RNA polymerase II core complex assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.
[ "GOC:rb", "PMID:23459708" ]
null
[ "DNA-directed RNA polymerase II, core complex assembly", "RNA Polymerase II assembly" ]
[ "EXACT", "BROAD" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[]
[]
[]
rb
2013-05-31T21:46:42Z
false
true
3
GO:1990115
1,990,115
RNA polymerase III assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex.
[ "GOC:rb", "PMID:23459708" ]
null
[ "DNA-directed RNA polymerase III complex assembly", "RNA Polymerase III complex assembly" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[ "GO:0065003" ]
[]
[]
[]
[]
[]
[]
rb
2013-05-31T21:49:19Z
false
true
7
GO:1990116
1,990,116
ribosome-associated ubiquitin-dependent protein catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein.
[ "GOC:dgf", "PMID:23358411" ]
null
[ "RAD", "ribosome-associated degradation", "ribosome-associated ubiquitin-dependent protein breakdown", "ribosome-associated ubiquitin-dependent protein catabolism", "ribosome-associated ubiquitin-dependent protein degradation" ]
[ "BROAD", "BROAD", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0043161" ]
[]
[]
[]
[ "GO:0043161" ]
[]
[]
[]
[]
[]
[]
pr
2013-06-05T11:46:01Z
false
true
5
GO:1990117
1,990,117
B cell receptor apoptotic signaling pathway
biological_process
An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell.
[ "GOC:BHF", "GOC:mtg_apoptosis", "GOC:rl", "PMID:15214043" ]
null
[ "B cell receptor extrinsic apoptotic signaling pathway", "extrinsic apoptotic signaling pathway via B cell antigen receptor", "extrinsic apoptotic signaling pathway via BCR" ]
[ "EXACT", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0050853", "GO:0097191" ]
[ "part_of GO:0001783" ]
[ "part_of" ]
[ "GO:0001783" ]
[ "GO:0001783", "GO:0050853", "GO:0097191" ]
[]
[]
[]
[]
[]
[]
pr
2013-06-06T15:15:17Z
false
true
4
GO:1990119
1,990,119
RNA helicase inhibitor activity
molecular_function
Binds to and stops, prevents or reduces the activity of an RNA helicase.
[ "GOC:rb", "PMID:23721653" ]
null
[ "ATP-dependent RNA helicase inhibitor activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0004857", "GO:0042030" ]
[ "negatively_regulates GO:0003724" ]
[ "negatively_regulates" ]
[ "GO:0003724" ]
[ "GO:0003724", "GO:0004857", "GO:0042030" ]
[]
[]
[]
[]
[]
[]
rb
2013-06-11T21:14:38Z
false
true
1
GO:1990120
1,990,120
obsolete messenger ribonucleoprotein complex assembly
biological_process
OBSOLETE. The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.
[ "GOC:rb", "PMID:23721653" ]
The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27077\" xsd:anyURI" ]
rb
2013-06-11T21:18:20Z
true
true
3
GO:1990121
1,990,121
H-NS complex
cellular_component
A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA.
[ "GOC:bhm", "PMID:12592399" ]
null
[ "DNA-binding protein H-NS complex", "histone-like protein H-NS complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990104" ]
[ "part_of GO:0005829", "part_of GO:0043590" ]
[ "part_of", "part_of" ]
[ "GO:0005829", "GO:0043590" ]
[ "GO:0005829", "GO:0043590", "GO:1990104" ]
[]
[]
[]
[]
[]
[]
bhm
2013-06-12T10:08:31Z
false
true
2
GO:1990124
1,990,124
obsolete messenger ribonucleoprotein complex
cellular_component
OBSOLETE. A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules.
[ "GOC:bf", "PMID:15574591", "PMID:21915786" ]
This term was obsoleted becasue it does not represent a specific complex
[ "messenger ribonucleoprotein particle", "mRNA-protein complex", "mRNP", "mRNP complex" ]
[ "RELATED", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
bf
2013-06-13T09:20:52Z
true
true
8
GO:1990125
1,990,125
DiaA complex
cellular_component
A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation.
[ "GOC:bhm", "PMID:17699754" ]
null
[ "DiaA homotetramer" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[]
bhm
2013-06-13T14:03:54Z
false
true
6
GO:1990127
1,990,127
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
biological_process
The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is trigge...
[ "GOC:krc", "GOC:mtg_apoptosis", "PMID:16571598" ]
null
[]
[]
[]
[]
[]
[ "GO:0008627", "GO:0072332" ]
[]
[]
[]
[ "GO:0008627", "GO:0072332" ]
[]
[]
[]
[]
[]
[]
pr
2013-06-19T13:55:06Z
false
true
4