LiteFold/GO · Datasets at Hugging Face

GO:1990128

1,990,128

obsolete pre-primosome complex involved in replication initiation

cellular_component

OBSOLETE. A protein-DNA complex involved in replication initiation at the origin of replication.

[ "GOC:bhm", "PMID:21856207" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "pre-primosome complex involved in replication initiation" ]

[ "EXACT" ]

[]

bhm

2013-06-24T10:29:39Z

true

9

GO:1990129

1,990,129

obsolete pre-primosome complex involved in replication restart

cellular_component

OBSOLETE. A protein-DNA complex involved in replication restart after a stalled replication fork has been repaired.

[ "GOC:bhm", "PMID:17139333" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "pre-primosome complex involved in replication restart" ]

[ "EXACT" ]

[]

bhm

2013-06-24T10:36:30Z

true

6

GO:1990130

1,990,130

GATOR1 complex

cellular_component

A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins.

[ "GOC:krc", "GOC:rb", "PMID:21900499", "PMID:23723238", "PMID:23974112", "PMID:25934700", "PMID:28199306", "PMID:29199950" ]

The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ; GO:1990131.

[ "IML1 complex", "SEACIT complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0035859" ]

[ "part_of" ]

[ "GO:0035859" ]

[ "GO:0032991", "GO:0035859" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21778\" xsd:anyURI" ]

rb

2013-06-25T17:34:40Z

false

true

9

GO:1990132

1,990,132

obsolete release of misfolded protein from chaperone

biological_process

OBSOLETE. The release of misfolded proteins that are being held by the chaperone heat shock protein (Hsp) and targeting them for destruction by the Ub-proteasome machinery.

[ "GOC:rb", "PMID:23530227" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "release of misfolded protein from chaperone" ]

[ "EXACT" ]

[]

rb

2013-06-25T21:56:37Z

true

7

GO:1990133

1,990,133

molybdopterin adenylyltransferase complex

cellular_component

A heterotetrameric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; in human the subunits are MOCS3 and MOCS2A. Moco biosynthesis and its constit...

[ "GOC:bhm", "PMID:11713534", "PMID:16669776", "PMID:18491921" ]

null

[ "molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex", "MPT adenylyltransferase complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:1902503" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1902503" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27852\" xsd:anyURI" ]

bhm

2013-06-26T10:54:21Z

false

true

2

GO:1990134

1,990,134

epithelial cell apoptotic process involved in palatal shelf morphogenesis

biological_process

An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.

[ "GOC:dph", "GOC:mtg_apoptosis", "PMID:16607638" ]

null

[]

[ "GO:0060561", "GO:1904019" ]

[ "part_of GO:0062009" ]

[ "part_of" ]

[ "GO:0062009" ]

[ "GO:0060561", "GO:0062009", "GO:1904019" ]

[]

dph

2013-06-26T11:56:00Z

false

true

2

GO:1990136

1,990,136

linoleate 9S-lipoxygenase activity

molecular_function

Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.

[ "GOC:rph", "RHEA:30291" ]

null

[ "9-lipoxygenase activity", "9S-lipoxygenase activity", "linoleate 9-lipoxygenase activity", "linoleate:oxygen 9S-oxidoreductase activity" ]

[ "RELATED", "RELATED", "RELATED", "EXACT" ]

[]

[ "EC:1.13.11.58", "RHEA:30291" ]

[ "GO:0016702" ]

[]

[ "GO:0016702" ]

[]

[ "skos:exactMatch EC:1.13.11.58", "skos:exactMatch RHEA:30291", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

pr

2013-07-03T12:20:57Z

false

true

3

GO:1990137

1,990,137

plant seed peroxygenase activity

molecular_function

Catalysis of the reaction: RH + ROOH = ROH + ROH.

[ "EC:1.11.2.3", "PMID:19467604" ]

null

[ "peroxygenase activity", "plant seed peroxidase activity" ]

[ "BROAD", "RELATED" ]

[]

[ "EC:1.11.2.3", "MetaCyc:RXN-1064", "MetaCyc:RXN-11819" ]

[ "GO:0016684" ]

[]

[ "GO:0016684" ]

[]

[ "skos:exactMatch EC:1.11.2.3", "skos:exactMatch MetaCyc:RXN-11819", "skos:narrowMatch MetaCyc:RXN-1064", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28070\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28526\" xsd:anyURI" ]

tb

2013-07-03T12:49:20Z

false

true

1

GO:1990138

1,990,138

neuron projection extension

biological_process

Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

[ "GOC:BHF", "GOC:rl", "PMID:22790009" ]

null

[ "neurite extension", "neuron process extension", "neuron protrusion extension", "neuronal cell projection extension" ]

[ "NARROW", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0048588", "GO:0060560" ]

[ "part_of GO:0048812" ]

[ "part_of" ]

[ "GO:0048812" ]

[ "GO:0048588", "GO:0048812", "GO:0060560" ]

[]

pr

2013-07-08T08:40:45Z

false

true

1

GO:1990139

1,990,139

protein localization to nuclear periphery

biological_process

A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.

[ "GOC:mah", "PMID:23703609" ]

null

[]

[ "GO:0034504" ]

[]

[ "GO:0034504" ]

[]

mah

2013-07-09T13:35:49Z

false

true

4

GO:1990140

1,990,140

molybdopterin synthase complex

cellular_component

A heterotetrameric protein complex that catalyses sulfur transfer from the sulfur carrier subunit of molybdopterin synthase to precursor Z to synthesize molybdopterin as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its ...

[ "GOC:bhm", "PMID:11135669", "PMID:16669776" ]

null

[ "molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex", "molybdopterin converting factor complex", "MPT synthase complex" ]

[ "RELATED", "EXACT", "EXACT" ]

[]

[ "goslim_metagenomics" ]

[]

[ "GO:1990228" ]

[]

[ "GO:1990228" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27655\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27852\" xsd:anyURI" ]

pr

2013-07-11T08:32:29Z

false

true

7

GO:1990143

1,990,143

CoA-synthesizing protein complex

cellular_component

A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step o...

[ "GOC:rb", "PMID:23789928" ]

null

[ "CoA-SPC", "coenzyme A-synthesizing protein complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:1902494" ]

[]

[ "GO:1902494" ]

[]

rb

2013-07-18T22:30:20Z

false

true

6

GO:1990144

1,990,144

intrinsic apoptotic signaling pathway in response to hypoxia

biological_process

The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the ce...

[ "GOC:BHF", "GOC:mtg_apoptosis", "GOC:rl", "PMID:20436456" ]

null

[]

[ "GO:0097193" ]

[ "part_of GO:0071456" ]

[ "part_of" ]

[ "GO:0071456" ]

[ "GO:0071456", "GO:0097193" ]

[]

pr

2013-07-23T10:18:10Z

false

true

2

GO:1990145

1,990,145

maintenance of translational fidelity

biological_process

Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.

[ "GOC:hjd", "ISBN:9781936113460", "PMID:21841312" ]

null

[]

[ "GO:0009059" ]

[ "part_of GO:0006412" ]

[ "part_of" ]

[ "GO:0006412" ]

[ "GO:0006412", "GO:0009059" ]

[]

hjd

2013-07-24T19:30:09Z

false

true

7

GO:1990146

1,990,146

protein localization to rhabdomere

biological_process

A process in which a protein is transported to, or maintained in, a location within a rhabdomere.

[ "GOC:sart", "PMID:8335687" ]

null

[]

[ "GO:0008104" ]

[]

[ "GO:0008104" ]

[]

sart

2013-07-25T11:24:49Z

false

true

5

GO:1990147

1,990,147

talin binding

molecular_function

Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types.

[ "GOC:hjd", "PMID:23372168" ]

null

[]

[ "GO:0008092" ]

[]

[ "GO:0008092" ]

[]

hjd

2013-07-25T19:49:53Z

false

true

1

GO:1990148

1,990,148

glutamate dehydrogenase complex

cellular_component

A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies.

[ "GOC:bhm", "PMID:22393408", "PMID:23412807" ]

null

[ "dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) complex", "glutamate dehydrogenase (NADP+) complex", "glutamic acid dehydrogenase complex", "glutamic dehydrogenase complex", "L-glutamate dehydrogenase complex", "L-glutamate:NADP+ oxidoreductase (deaminating) complex", "L-glutam...

[ "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED", "RELATED" ]

[]

[ "GO:1990204" ]

[]

[ "GO:1990204" ]

[]

pr

2013-07-26T10:14:15Z

false

true

8

GO:1990149

1,990,149

obsolete COPI vesicle coating

biological_process

OBSOLETE. The addition of COPI proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.

[ "GOC:rb", "PMID:11970962" ]

This term was obsoleted at the TermGenie Gatekeeper stage because COPI vesicles are formed on Golgi membranes, and the existing term 'COPI coating of Golgi vesicle ; GO:0048205' describes this process.

[ "COPI vesicle coating" ]

[ "EXACT" ]

[]

rb

2013-07-29T22:09:37Z

true

7

GO:1990150

1,990,150

VEGF-A complex

cellular_component

A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase.

[ "GOC:bf", "GOC:bhm", "PMID:12207021", "PMID:19658168" ]

null

[ "vascular endothelial growth factor A complex" ]

[ "EXACT" ]

[]

[ "GO:0036454" ]

[]

[ "GO:0036454" ]

[]

bhm

2013-07-30T13:24:41Z

false

true

6

GO:1990153

1,990,153

maintenance of protein localization to heterochromatin

biological_process

A process in which a protein is maintained in a location in telomeric heterochromatin.

[ "PMID:21300781" ]

null

[ "maintenance of protein localisation to heterochromatin", "maintenance of protein location in heterochromatin" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0032507" ]

[ "part_of GO:0097355" ]

[ "part_of" ]

[ "GO:0097355" ]

[ "GO:0032507", "GO:0097355" ]

[]

mah

2013-07-31T15:11:37Z

false

true

7

GO:1990154

1,990,154

enzyme IIA-maltose transporter complex

cellular_component

A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, in...

[ "GOC:bf", "GOC:bhm", "PMID:23770568" ]

null

[ "EIIA(Glc)-MalFGK2 complex", "EIIA(Glc)-maltose transporter complex", "maltose transporter inhibitor complex" ]

[ "EXACT", "EXACT", "RELATED" ]

[]

[ "GO:0043190" ]

[ "has_part GO:1990060" ]

[ "has_part" ]

[ "GO:1990060" ]

[ "GO:0043190", "GO:1990060" ]

[]

bhm

2013-08-01T09:27:25Z

false

true

7

GO:1990155

1,990,155

Dsc E3 ubiquitin ligase complex assembly

biological_process

The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane.

[ "GOC:mah", "PMID:23760507" ]

null

[ "Dsc complex assembly" ]

[ "EXACT" ]

[]

[ "GO:0065003" ]

[]

[ "GO:0065003" ]

[]

mah

2013-08-01T14:19:19Z

false

true

4

GO:1990157

1,990,157

DnaA-DnaB-DnaC complex

cellular_component

A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation.

[ "GOC:bhm", "PMID:20129058" ]

null

[]

[ "GO:1990099" ]

[ "has_part GO:1990100" ]

[ "has_part" ]

[ "GO:1990100" ]

[ "GO:1990099", "GO:1990100" ]

[]

bhm

2013-08-02T11:42:27Z

false

true

5

GO:1990158

1,990,158

DnaB-DnaC-DnaT-PriA-PriB complex

cellular_component

A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.

[ "GOC:bhm", "PMID:8663105" ]

null

[ "DnaB-DnaC-DnaT-PriA-PriB preprimosome", "phi-X174-type preprimosome" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:1990099" ]

[ "has_part GO:1990100" ]

[ "has_part" ]

[ "GO:1990100" ]

[ "GO:1990099", "GO:1990100" ]

[]

bhm

2013-08-02T11:52:55Z

false

true

6

GO:1990159

1,990,159

DnaB-DnaC-DnaT-PriA-PriC complex

cellular_component

A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.

[ "GOC:bhm", "PMID:8663105" ]

null

[ "DnaB-DnaC-DnaT-PriA-PriC preprimosome", "phi-X174-type preprimosome" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:1990099" ]

[ "has_part GO:1990100" ]

[ "has_part" ]

[ "GO:1990100" ]

[ "GO:1990099", "GO:1990100" ]

[]

bhm

2013-08-02T11:58:16Z

false

true

6

GO:1990160

1,990,160

DnaB-DnaC-Rep-PriC complex

cellular_component

A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.

[ "GOC:bhm", "PMID:19941825", "PMID:8663105" ]

null

[ "DnaB-DnaC-Rep-PriC preprimosome", "phi-X174-type preprimosome" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:1990099" ]

[ "has_part GO:1990100" ]

[ "has_part" ]

[ "GO:1990100" ]

[ "GO:1990099", "GO:1990100" ]

[]

bhm

2013-08-02T12:05:25Z

false

true

1

GO:1990161

1,990,161

DnaB helicase complex

cellular_component

A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair.

[ "GOC:bhm", "PMID:17947583" ]

null

[ "DnaB hexamer" ]

[ "EXACT" ]

[]

[ "GO:0033202" ]

[]

[ "GO:0033202" ]

[]

bhm

2013-08-02T15:55:48Z

false

true

2

GO:1990162

1,990,162

histone H3K4 deacetylase activity, hydrolytic mechanism

molecular_function

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.

[ "GOC:al", "PMID:23771057", "PMID:28450737" ]

Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...

[ "histone deacetylase activity (H3-K4 specific)", "histone H3-K4 deacetylase activity", "histone H3K14 deacetylase activity" ]

[ "BROAD", "EXACT", "BROAD" ]

[]

[ "GO:0141050", "GO:0141221" ]

[]

[ "GO:0141050", "GO:0141221" ]

[]

[ "skos:broadMatch EC:3.5.1.98", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]

pr

2013-08-06T08:48:44Z

false

true

3

GO:1990164

1,990,164

obsolete histone H2A phosphorylation

biological_process

OBSOLETE. The modification of histone H2A by the addition of a phosphate group.

[ "GOC:mah", "PMID:23080121" ]

This term was obsoleted because it represents a molecular function.

[]

[ "GO:0035173" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23140\" xsd:anyURI" ]

mah

2013-08-08T11:13:25Z

true

3

GO:1990165

1,990,165

single-strand break-containing DNA binding

molecular_function

Binding to damaged DNA containing single-strand breaks (SSBs).

[ "GOC:al", "PMID:21984210" ]

null

[ "single-strand break-containing damaged DNA binding", "SSB-containing DNA binding" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0003684" ]

[]

[ "GO:0003684" ]

[]

pr

2013-08-08T11:16:04Z

false

true

5

GO:1990166

1,990,166

protein localization to site of double-strand break

biological_process

Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred.

[ "GOC:mah", "PMID:23080121" ]

null

[ "protein localisation to site of double-strand break", "protein localization to double-strand break site", "protein localization to site of DSB" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0034502" ]

[]

[ "GO:0034502" ]

[]

mah

2013-08-08T11:27:00Z

false

true

4

GO:1990167

1,990,167

protein K27-linked deubiquitination

biological_process

A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein.

[ "PMID:23827681" ]

null

[]

[ "GO:0016579" ]

[]

[ "GO:0016579" ]

[]

sp

2013-08-14T11:15:24Z

false

true

6

GO:1990168

1,990,168

protein K33-linked deubiquitination

biological_process

A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.

[ "PMID:23827681" ]

null

[]

[ "GO:0016579" ]

[]

[ "GO:0016579" ]

[]

sp

2013-08-14T11:19:39Z

false

true

4

GO:1990169

1,990,169

stress response to copper ion

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus.

[ "GOC:kmv", "PMID:23437011" ]

null

[ "response to copper ion stress", "response to copper toxicity", "stress response to copper" ]

[ "EXACT", "RELATED", "BROAD" ]

[]

[ "GO:0046688", "GO:0097501" ]

[]

[ "GO:0046688", "GO:0097501" ]

[]

pr

2013-08-14T12:52:05Z

false

true

5

GO:1990170

1,990,170

stress response to cadmium ion

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus.

[ "GOC:kmv" ]

null

[ "response to cadmium ion stress", "response to cadmium toxicity", "stress response to cadmium" ]

[ "EXACT", "RELATED", "BROAD" ]

[]

[ "GO:0046686", "GO:0097501" ]

[]

[ "GO:0046686", "GO:0097501" ]

[]

pr

2013-08-14T12:55:45Z

false

true

1

GO:1990172

1,990,172

G protein-coupled receptor catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor.

[ "PMID:12142540", "PMID:23954414" ]

null

[ "G-protein coupled receptor catabolic process" ]

[ "EXACT" ]

[]

[ "GO:0032801", "GO:0045744" ]

[]

[ "GO:0032801", "GO:0045744" ]

[]

sp

2013-08-22T10:16:58Z

false

true

7

GO:1990173

1,990,173

protein localization to nucleoplasm

biological_process

A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.

[ "GOC:mah", "PMID:22918952" ]

null

[ "nucleolus to nucleoplasm transport", "protein localisation to nucleoplasm" ]

[ "RELATED", "EXACT" ]

[ "GO:0032066" ]

[]

[ "GO:0034504" ]

[]

[ "GO:0034504" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14690\" xsd:anyURI" ]

mah

2013-08-23T15:01:16Z

false

true

3

GO:1990174

1,990,174

phosphodiesterase decapping endonuclease activity

molecular_function

Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA.

[ "GOC:dgf", "PMID:20802481" ]

null

[ "G(5')pppN pyrophosphatase activity" ]

[ "RELATED" ]

[]

[ "Reactome:R-HSA-9935300 \"DXO decaps NAD-capped RNA (NAD-RNA)\"", "Reactome:R-HSA-9935319 \"DXO decaps incompletely capped RNA (GpppN-RNA)\"" ]

[ "GO:0016891" ]

[]

[ "GO:0016891" ]

[]

tb

2013-08-26T17:51:00Z

false

true

4

GO:1990176

1,990,176

MalFGK2 complex

cellular_component

Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG.

[ "GOC:bhm", "PMID:19250913" ]

The MalFGK2 complex lacks the maltose-binding subunit present in GO:1990060.

[ "MalF-MalG-MalK(2) complex", "MalF-MalG-MalK-MalK complex", "MalFGK(2) complex", "maltose transport complex, core subunit", "maltose transport MalFGK2 complex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0098797" ]

[ "part_of GO:1990060" ]

[ "part_of" ]

[ "GO:1990060" ]

[ "GO:0098797", "GO:1990060" ]

[]

bhm

2013-08-30T11:10:14Z

false

true

8

GO:1990177

1,990,177

IHF-DNA complex

cellular_component

A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid.

[ "GOC:bhm", "PMID:17097674" ]

null

[ "IHF complex", "IHFa-IHFb-DNA complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0032993", "GO:1990104" ]

[ "part_of GO:0043590" ]

[ "part_of" ]

[ "GO:0043590" ]

[ "GO:0032993", "GO:0043590", "GO:1990104" ]

[]

bhm

2013-08-30T12:22:54Z

false

true

7

GO:1990178

1,990,178

HU-DNA complex

cellular_component

A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure.

[ "GOC:bhm", "PMID:17360520" ]

null

[ "HU complex" ]

[ "BROAD" ]

[]

[ "GO:0032993", "GO:1990104" ]

[ "part_of GO:0043590" ]

[ "part_of" ]

[ "GO:0043590" ]

[ "GO:0032993", "GO:0043590", "GO:1990104" ]

[]

bhm

2013-08-30T13:06:53Z

false

true

2

GO:1990179

1,990,179

protein localization to actomyosin contractile ring

biological_process

A process in which a protein is transported to, or maintained at, the actomyosin contractile ring.

[ "GOC:mah", "PMID:23349808" ]

null

[ "protein localisation to actomyosin contractile ring" ]

[ "EXACT" ]

[]

[ "GO:0072697", "GO:0072741", "GO:1903119" ]

[]

[ "GO:0072697", "GO:0072741", "GO:1903119" ]

[]

mah

2013-08-30T16:13:54Z

false

true

7

GO:1990180

1,990,180

mitochondrial tRNA 3'-end processing

biological_process

The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.

[ "GOC:mah", "GOC:TermGenie", "PMID:23928301" ]

null

[ "tRNA 3' processing in mitochondria", "tRNA 3' processing in mitochondrion", "tRNA 3'-end processing in mitochondria" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0000965", "GO:0042780", "GO:0090646" ]

[]

[ "GO:0000965", "GO:0042780", "GO:0090646" ]

[ "GO:0042780", "occurs_in GO:0005739" ]

[]

mah

2013-08-30T16:17:36Z

false

true

5

GO:1990181

1,990,181

obsolete acetyl-CoA biosynthetic process from pantothenate

biological_process

OBSOLETE. The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA.

[ "GOC:mah", "PMID:23091701" ]

The reason for obsoletion is that these represent GO-CAMs.

[ "acetyl-CoA anabolism from pantothenate", "acetyl-CoA formation from pantothenate", "acetyl-CoA synthesis from pantothenate" ]

[ "EXACT", "RELATED", "RELATED" ]

[]

[ "GO:0006085" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31666\" xsd:anyURI" ]

mah

2013-08-30T16:20:44Z

true

7

GO:1990182

1,990,182

exosomal secretion

biological_process

The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.

[ "GOC:hjd", "PMID:10572093", "PMID:12154376", "PMID:16773132", "PMID:18617898" ]

null

[ "exosomal protein secretion", "exosomal secretory pathway", "extracellular vesicular exosome secretion", "multi-vesicular body fusion with plasma membrane", "secretion of exosome" ]

[ "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0006887", "GO:0051650" ]

[ "part_of GO:0097734" ]

[ "part_of" ]

[ "GO:0097734" ]

[ "GO:0006887", "GO:0051650", "GO:0097734" ]

[]

hjd

2013-09-04T21:08:14Z

false

true

8

GO:1990183

1,990,183

lymphatic vascular process in circulatory system

biological_process

A circulatory process that occurs at the level of the lymphatic vasculature.

[ "PMID:21576390" ]

null

[]

[ "GO:0003018" ]

[]

[ "GO:0003018" ]

[]

sl

2013-09-10T22:26:40Z

false

true

4

GO:1990184

1,990,184

amino acid transport complex

cellular_component

A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane.

[ "GOC:kmv", "PMID:14668347" ]

null

[]

[ "GO:0098797" ]

[]

[ "GO:0098797" ]

[]

jl

2013-09-11T15:02:16Z

false

true

1

GO:1990185

1,990,185

regulation of lymphatic vascular permeability

biological_process

Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.

[ "PMID:23897233" ]

null

[]

[ "GO:0043114", "GO:1990183" ]

[]

[ "GO:0043114", "GO:1990183" ]

[]

sl

2013-09-11T15:36:22Z

false

true

1

GO:1990186

1,990,186

regulation of lymphatic vessel size

biological_process

Any process that modulates the size of lymphatic vessels.

[ "PMID:23897233" ]

null

[ "regulation of collecting lymphatic vessel size" ]

[ "NARROW" ]

[]

[ "GO:0090066", "GO:1990183" ]

[]

[ "GO:0090066", "GO:1990183" ]

[]

sl

2013-09-11T15:41:16Z

false

true

9

GO:1990187

1,990,187

obsolete protein localization to mRNA

biological_process

OBSOLETE. A process in which a protein is transported to, or maintained at mRNA.

[ "GOC:rb", "PMID:22890846" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "protein localization to mRNA" ]

[ "EXACT" ]

[]

rb

2013-09-11T18:19:20Z

true

2

GO:1990188

1,990,188

euchromatin binding

molecular_function

Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.

[ "GOC:vw", "PMID:22431512" ]

null

[]

[ "GO:0003682" ]

[]

[ "GO:0003682" ]

[]

tb

2013-09-11T19:18:38Z

false

true

9

GO:1990189

1,990,189

protein N-terminal-serine acetyltransferase activity

molecular_function

Catalysis of the reaction: acetyl-CoA + N-terminal L-seryl-[protein] = CoA + H+ + N-terminal Nalpha-acetyl-L-seryl-[protein].

[ "PMID:23912279", "RHEA:50504" ]

null

[ "peptide-serine-alpha-N-acetyltransferase activity" ]

[ "EXACT" ]

[]

[ "EC:2.3.1.257", "RHEA:43760", "RHEA:50504", "RHEA:50596", "RHEA:50600" ]

[ "GO:0004596" ]

[]

[ "GO:0004596" ]

[]

[ "skos:exactMatch RHEA:50504", "skos:narrowMatch EC:2.3.1.257", "skos:narrowMatch RHEA:43760", "skos:narrowMatch RHEA:50596", "skos:narrowMatch RHEA:50600", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27532\" xsd:anyURI" ]

tb

2013-09-11T20:13:40Z

false

true

6

GO:1990190

1,990,190

protein-N-terminal-glutamate acetyltransferase activity

molecular_function

Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide.

[ "GOC:al", "PMID:23912279" ]

null

[ "peptide-glutamate-alpha-N-acetyltransferase activity", "protein-N-terminal-glutamate-alpha-N-acetyltransferase activity" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0004596" ]

[]

[ "GO:0004596" ]

[]

tb

2013-09-11T20:21:25Z

false

true

8

GO:1990192

1,990,192

collecting lymphatic vessel constriction

biological_process

A decrease in the diameter of collecting lymphatic vessels.

[ "PMID:23322290" ]

null

[ "lymphatic vessel myogenic constriction" ]

[ "EXACT" ]

[]

[ "GO:1990186" ]

[]

[ "GO:1990186" ]

[]

sl

2013-09-12T14:46:05Z

false

true

2

GO:1990193

1,990,193

BtuCD complex

cellular_component

Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer.

[ "GOC:bhm", "PMID:22569249" ]

null

[ "BtuC-BtuD complex", "cobalamin transport complex, core subunit", "vitamin B12 transport complex, core subunit" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0043190" ]

[]

[ "GO:0043190" ]

[]

bhm

2013-09-12T14:58:56Z

false

true

3

GO:1990194

1,990,194

cytoplasmic U snRNP body assembly

biological_process

The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body.

[ "PMID:19464282" ]

null

[ "U body assembly" ]

[ "RELATED" ]

[]

[ "GO:0022618", "GO:0140694" ]

[]

[ "GO:0022618", "GO:0140694" ]

[]

tb

2013-09-12T21:54:20Z

false

true

7

GO:1990195

1,990,195

macrolide transmembrane transporter complex

cellular_component

A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (...

[ "GOC:bhm", "PMID:10879525", "PMID:18955484", "PMID:19254725" ]

null

[ "AcrAB-TolC complex", "MacAB-TolC complex", "macrolide transporter", "macrolide transporter complex" ]

[ "NARROW", "NARROW", "RELATED", "BROAD" ]

[]

[ "GO:1902495" ]

[]

[ "GO:1902495" ]

[]

bhm

2013-09-23T11:22:26Z

false

true

5

GO:1990196

1,990,196

MacAB-TolC complex

cellular_component

The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA ...

[ "GOC:bhm", "PMID:10879525", "PMID:18955484", "PMID:19254725" ]

null

[ "macrolide transporter MacAB-TolC complex" ]

[ "EXACT" ]

[]

[ "GO:1990195" ]

[]

[ "GO:1990195" ]

[]

bhm

2013-09-23T11:29:28Z

false

true

4

GO:1990197

1,990,197

methionine-importing ABC transporter complex

cellular_component

An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regar...

[ "GOC:bhm", "PMID:22095702" ]

null

[ "ATP-binding cassette (ABC) methionine importer complex", "ATP-dependent methionine importer complex", "ATP-dependent methionine importing complex", "ATP-dependent methionine-importing complex", "methionine transport complex", "methionine transporter", "methionine transporter complex", "methionine tra...

[ "EXACT", "EXACT", "EXACT", "EXACT", "BROAD", "RELATED", "BROAD", "BROAD", "NARROW", "NARROW", "RELATED", "NARROW", "NARROW", "NARROW", "RELATED", "RELATED" ]

[]

[ "GO:0043190", "GO:1902509" ]

[]

[ "GO:0043190", "GO:1902509" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21619\" xsd:anyURI" ]

bhm

2013-09-26T09:38:26Z

false

true

4

GO:1990198

1,990,198

ModE complex

cellular_component

A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.

[ "GOC:bhm", "PMID:12581638" ]

null

[ "ModE dimer" ]

[ "EXACT" ]

[]

[ "GO:0005667" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005667", "GO:0005829" ]

[]

bhm

2013-10-01T07:28:52Z

false

true

8

GO:1990199

1,990,199

MsbA transporter complex

cellular_component

An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ...

[ "GOC:bhm", "PMID:18024585" ]

null

[ "MsbA complex", "MsbA dimer" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0043190" ]

[]

[ "GO:0043190" ]

[]

bhm

2013-10-01T07:49:41Z

false

true

8

GO:1990200

1,990,200

SsuD-SsuE complex

cellular_component

A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation.

[ "GOC:bhm", "PMID:16997955" ]

null

[ "two-component alkanesulfonate monooxygenase system" ]

[ "RELATED" ]

[]

[ "GO:0032991" ]

[ "has_part GO:1990201", "has_part GO:1990202", "part_of GO:0005829" ]

[ "has_part", "has_part", "part_of" ]

[ "GO:1990201", "GO:1990202", "GO:0005829" ]

[ "GO:0005829", "GO:0032991", "GO:1990201", "GO:1990202" ]

[]

bhm

2013-10-03T12:59:26Z

false

true

9

GO:1990201

1,990,201

alkanesulfonate monooxygenase complex

cellular_component

A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer.

[ "GOC:bhm", "PMID:10480865", "PMID:16997955" ]

null

[ "SsuD complex" ]

[ "NARROW" ]

[]

[ "GO:1990204" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1990204" ]

[]

bhm

2013-10-03T14:55:08Z

false

true

7

GO:1990202

1,990,202

FMN reductase complex

cellular_component

A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer.

[ "GOC:bhm", "PMID:10480865", "PMID:16997955" ]

null

[ "flavin oxidoreductase complex, NAD(P)H-dependent", "FMN oxidoreductase complex, NAD(P)H-dependent", "FMN reductase complex, NAD(P)H-dependent", "SsuE complex" ]

[ "BROAD", "RELATED", "EXACT", "NARROW" ]

[]

[ "GO:1990204" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1990204" ]

[]

bhm

2013-10-03T15:07:20Z

false

true

2

GO:1990205

1,990,205

taurine dioxygenase complex

cellular_component

A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD.

[ "GOC:bhm", "PMID:12741810" ]

null

[ "2-aminoethanesulfonate dioxygenase complex", "alpha-ketoglutarate-dependent taurine dioxygenase complex", "TauD complex" ]

[ "EXACT", "EXACT", "NARROW" ]

[]

[ "GO:1990204" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1990204" ]

[]

bhm

2013-10-07T13:03:15Z

false

true

2

GO:1990207

1,990,207

EmrE multidrug transporter complex

cellular_component

A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer...

[ "GOC:bhm", "PMID:18024586" ]

null

[ "EmrE complex" ]

[ "NARROW" ]

[]

[ "GO:0098797", "GO:1902495" ]

[]

[ "GO:0098797", "GO:1902495" ]

[]

bhm

2013-10-08T08:37:52Z

false

true

6

GO:1990208

1,990,208

obsolete positive regulation by symbiont of RNA levels in host

biological_process

OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:12182338", "PMID:18703740" ]

This term was obsoleted because it represents a readout.

[]

[ "GO:0052167" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23631\" xsd:anyURI" ]

ml

2013-10-08T13:31:41Z

true

3

GO:1990209

1,990,209

obsolete negative regulation by symbiont of RNA levels in host

biological_process

OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "GOC:ml", "PMID:18703740" ]

This term was obsoleted because it represents a readout.

[]

[ "GO:0052167" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23631\" xsd:anyURI" ]

ml

2013-10-09T18:09:33Z

true

5

GO:1990210

1,990,210

obsolete positive regulation by symbiont of indole acetic acid levels in host

biological_process

OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "GOC:ml", "PMID:18056646" ]

This term was obsoleted because there is no evidence that this process exists.

[ "positive regulation by symbiont of auxin levels in host", "positive regulation by symbiont of IAA levels in host" ]

[ "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26646\" xsd:anyURI" ]

ml

2013-10-09T18:54:11Z

true

7

GO:1990213

1,990,213

obsolete negative regulation by symbiont of salicylic acid levels in host

biological_process

OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "GOC:ml", "PMID:17722699", "PMID:20565685" ]

This term was obsoleted because there is no evidence that this process exists.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26646\" xsd:anyURI" ]

ml

2013-10-09T19:06:19Z

true

8

GO:1990214

1,990,214

obsolete negative regulation by symbiont of host protein levels

biological_process

OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:16840699", "PMID:22233353" ]

This term was obsoleted because it is a readout, and annotations should be made to more informative terms.

[]

ml

2013-10-10T15:39:45Z

true

9

GO:1990215

1,990,215

symbiont-mediated perturbation of host vesicle-mediated transport

biological_process

A process in which a symbiont alters or subverts vesicle-mediated transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:22319451", "PMID:24248335", "PMID:30893609", "PMID:31492901" ]

null

[ "negative regulation by symbiont of host intracellular transport", "symbiont-mediated perturbation of host endosomal trafficking" ]

[ "BROAD", "RELATED" ]

[]

[ "GO:0044068" ]

[]

[ "GO:0044068" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26919\" xsd:anyURI" ]

ml

2013-10-10T15:42:22Z

false

true

5

GO:1990217

1,990,217

symbiont-mediated suppression of host phytoalexin production

biological_process

A process in which a symbiont inhibits or disrupts the production of phytoalexins in the host organism. Phytoalexins are produced by plants to fight against pathogens. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:21402357" ]

null

[ "negative regulation by symbiont of host phytoalexin production", "suppression by symbiont of host phytoalexin production" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0052165" ]

[]

[ "GO:0052165" ]

[]

ml

2013-10-10T15:49:33Z

false

true

6

GO:1990218

1,990,218

obsolete positive regulation by symbiont of abscisic acid levels in host

biological_process

OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:17304219" ]

This term was obsoleted because there is no evidence that this process exists.

[]

ml

2013-10-10T15:54:10Z

true

1

GO:1990219

1,990,219

obsolete positive regulation by symbiont of host protein levels

biological_process

OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:20615948" ]

This term was obsoleted because it is a readout, and annotations should be made to more informative terms.

[]

ml

2013-10-10T17:26:03Z

true

1

GO:1990220

1,990,220

GroEL-GroES complex

cellular_component

Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins.

[ "GOC:bhm", "PMID:15313620" ]

null

[ "bacterial chaperonin ATPase complex", "bacterial chaperonin complex" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0016465" ]

[]

[ "GO:0016465" ]

[]

bhm

2013-10-11T09:20:01Z

false

true

5

GO:1990221

1,990,221

L-cysteine desulfurase complex

cellular_component

A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes.

[ "GOC:bhm", "PMID:11827487" ]

null

[ "IscS", "NifS", "SufS complex" ]

[ "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:1990228" ]

[]

[ "GO:1990228" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27651\" xsd:anyURI" ]

bhm

2013-10-11T15:36:34Z

false

true

6

GO:1990222

1,990,222

ProVWX complex

cellular_component

The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma m...

[ "GOC:bhm", "PMID:23249124" ]

null

[ "ATP-binding cassette (ABC) transporter complex ProVWX" ]

[ "EXACT" ]

[]

[ "GO:0043190" ]

[]

[ "GO:0043190" ]

[]

bhm

2013-10-16T09:09:17Z

false

true

3

GO:1990223

1,990,223

obsolete positive regulation by symbiont of cytokinin levels in host

biological_process

OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.

[ "PMID:24124900" ]

This term was obsoleted because there is no evidence that this process exists.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26646\" xsd:anyURI" ]

ml

2013-10-16T15:27:27Z

true

7

GO:1990224

1,990,224

obsolete NMN phosphatase activity

molecular_function

OBSOLETE. Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate.

[ "GOC:rb", "PMID:21349851" ]

The reason for obsoletion is that it is more specific than the specificity of any known gene product.

[ "beta-nicotinamide D-ribonucleotide phosphatase activity", "nicotinamide mononucleotide phosphatase activity" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0008253" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29438\" xsd:anyURI" ]

rb

2013-10-21T18:03:41Z

true

1

GO:1990225

1,990,225

rhoptry neck

cellular_component

Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion.

[ "GOC:giardia", "GOC:pr", "PMID:23499754", "PMID:23937520", "PMID:24002067", "PMID:24070999" ]

null

[]

[ "GO:0110165" ]

[ "part_of GO:0020008" ]

[ "part_of" ]

[ "GO:0020008" ]

[ "GO:0020008", "GO:0110165" ]

[]

pr

2013-11-03T14:19:26Z

false

true

3

GO:1990226

1,990,226

histone methyltransferase binding

molecular_function

Binding to a histone methyltransferase enzyme.

[ "GOC:ame", "GOC:BHF", "PMID:19486527" ]

null

[]

[ "GO:0019899" ]

[]

[ "GO:0019899" ]

[]

pr

2013-11-07T11:59:58Z

false

true

3

GO:1990228

1,990,228

sulfurtransferase complex

cellular_component

A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor).

[ "GOC:bhm", "PMID:17350958" ]

null

[ "SufE complex", "SufE dimer", "sulfur transfer complex", "ThiF-ThiS complex" ]

[ "NARROW", "NARROW", "EXACT", "RELATED" ]

[]

[ "GO:1990234" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1990234" ]

[]

bhm

2013-11-12T09:08:23Z

false

true

8

GO:1990229

1,990,229

iron-sulfur cluster assembly complex

cellular_component

A protein complex capable of assembling an iron-sulfur (Fe-S) cluster.

[ "GOC:bhm", "PMID:17350958" ]

null

[ "Fe-S cluster assembly complex", "SufBCD complex" ]

[ "NARROW", "NARROW" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:0032991" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29899\" xsd:anyURI" ]

bhm

2013-11-12T09:15:03Z

false

true

7

GO:1990230

1,990,230

iron-sulfur cluster transfer complex

cellular_component

A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor), which may be a target protein or another Fe-S assembly complex. In humans, it consists of HSPA9, HSCB, GLRX5, ABCB7 and GFER.

[ "GOC:bhm", "PMID:19810706", "PMID:34660592" ]

null

[ "Fe-S cluster transfer complex", "IscA complex", "SufA complex", "SufA dimer" ]

[ "EXACT", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:1990234" ]

[]

[ "GO:1990234" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27652\" xsd:anyURI" ]

bhm

2013-11-12T09:17:40Z

false

true

7

GO:1990231

1,990,231

STING complex

cellular_component

A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines a...

[ "GOC:bhm", "PMID:22705373", "PMID:23706668", "PMID:23910378" ]

null

[ "stimulator of interferon genes complex" ]

[ "EXACT" ]

[]

[ "GO:0098796" ]

[ "part_of GO:0030659" ]

[ "part_of" ]

[ "GO:0030659" ]

[ "GO:0030659", "GO:0098796" ]

[]

bhm

2013-11-12T10:58:34Z

false

true

7

GO:1990232

1,990,232

phosphomannomutase complex

cellular_component

A protein complex capable of phosphomannomutase activity.

[ "GOC:bhm", "PMID:16540464" ]

null

[ "PMM-1 complex", "PMM-1 dimer", "PMM-2 complex", "PMM-2 dimer" ]

[ "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:1990233" ]

[]

[ "GO:1990233" ]

[]

bhm

2013-11-12T13:05:54Z

false

true

6

GO:1990233

1,990,233

intramolecular phosphotransferase complex

cellular_component

A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule.

[ "GOC:bhm", "PMID:16540464" ]

null

[]

[ "GO:1902494" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1902494" ]

[]

bhm

2013-11-12T13:10:12Z

false

true

6

GO:1990234

1,990,234

transferase complex

cellular_component

A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).

[ "GOC:bhm", "PMID:16540464" ]

null

[]

[ "GO:1902494" ]

[]

[ "GO:1902494" ]

[]

bhm

2013-11-12T13:20:12Z

false

true

4

GO:1990235

1,990,235

diamine N-acetyltransferase complex

cellular_component

A protein complex which is capable of diamine N-acetyltransferase activity.

[ "GOC:bhm", "PMID:8077207" ]

null

[ "SAT complex", "SAT tetramer", "spermidine acetyltransferase complex" ]

[ "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:1902493" ]

[ "part_of GO:0005829" ]

[ "part_of" ]

[ "GO:0005829" ]

[ "GO:0005829", "GO:1902493" ]

[]

bhm

2013-11-13T16:29:45Z

false

true

1

GO:1990238

1,990,238

double-stranded DNA endonuclease activity

molecular_function

Catalysis of the hydrolysis of ester linkages within a double-stranded DNA molecule by creating internal breaks.

[ "PMID:22885404" ]

null

[ "double-stranded DNA endodeoxyribonuclease activity", "dsDNA-specific endodeoxyribonuclease activity" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0004520", "GO:0016788" ]

[]

[ "GO:0004520", "GO:0016788" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24408\" xsd:anyURI" ]

pg

2013-11-15T00:59:42Z

false

true

7

GO:1990239

1,990,239

steroid hormone binding

molecular_function

Binding to a steroid hormone.

[ "GOC:ln" ]

null

[]

[ "GO:0005496", "GO:0042562" ]

[]

[ "GO:0005496", "GO:0042562" ]

[]

pr

2013-11-15T09:26:18Z

false

true

7

GO:1990241

1,990,241

obsolete nucleotide binding complex

cellular_component

OBSOLETE. A protein complex that interacts selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. An example of this is STING in E. coli (Q86WV6).

[ "GOC:bhm", "PMID:23910378" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "nucleotide binding complex" ]

[ "EXACT" ]

[]

bhm

2013-11-22T16:22:07Z

true

1

GO:1990242

1,990,242

obsolete innate immune response complex

cellular_component

OBSOLETE. A protein complex involved in the innate immune response.

[ "GOC:bhm", "PMID:23910378" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "innate immune response complex" ]

[ "EXACT" ]

[]

bhm

2013-11-26T13:36:52Z

true

2

GO:1990243

1,990,243

atf1-pcr1 complex

cellular_component

A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).

[ "PMID:24224056" ]

null

[]

[ "GO:0035976" ]

[]

[ "GO:0035976" ]

[]

al

2013-11-28T11:40:28Z

false

true

1

GO:1990244

1,990,244

histone H2AT120 kinase activity

molecular_function

Catalysis of the reaction: histone H2A-threonine (position 120) + ATP = histone H2A-phosphothreonine (position 120) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 120 of histone H2A.

[ "PMID:24140421" ]

Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes, but corresponds to T119 in Drosophila and S121 in yeast and Tetrahymena. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that eac...

[ "histone H2A-T120 kinase activity", "histone H2AS120 kinase activity", "histone kinase activity (H2A-T120 specific)", "histone threonine kinase activity (H2A-T120 specific)" ]

[ "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0004674", "GO:0140995" ]

[]

[ "GO:0004674", "GO:0140995" ]

[]

[ "skos:broadMatch EC:2.7.11.1", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30578\" xsd:anyURI" ]

sp

2013-12-04T06:38:32Z

false

true

3

GO:1990245

1,990,245

obsolete histone H2A-T120 phosphorylation

biological_process

OBSOLETE. The modification of histone H2A by the addition of a phosphate group to a threonine residue at position 120 of the histone.

[ "PMID:24140421" ]

This term was obsoleted because it represents a molecular function.

[ "histone H2A phosphorylation at T120", "histone H2AT120 phosphorylation" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:1990244" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23140\" xsd:anyURI" ]

sp

2013-12-04T06:41:30Z

true

3

GO:1990246

1,990,246

uniplex complex

cellular_component

A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU re...

[ "PMID:24231807" ]

null

[ "mitochondrial uniporter complex", "mitochondrial uniporter holocomplex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0034704", "GO:0098800" ]

[]

[ "GO:0034704", "GO:0098800" ]

[]

sp

2013-12-04T06:44:35Z

false

true

6

GO:1990247

1,990,247

N6-methyladenosine-containing RNA reader activity

molecular_function

A protein adaptor that recognizes and binds an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs.

[ "PMID:22575960", "PMID:24284625" ]

null

[ "N6-methyladenosine-containing RNA binding" ]

[ "RELATED" ]

[]

[ "GO:0140517" ]

[ "has_part GO:0003723" ]

[ "has_part" ]

[ "GO:0003723" ]

[ "GO:0003723", "GO:0140517" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25788\" xsd:anyURI" ]

sp

2013-12-04T06:55:29Z

false

true

9

GO:1990249

1,990,249

nucleotide-excision repair, DNA damage recognition complex

cellular_component

A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision com...

[ "GOC:bhm", "PMID:22331906" ]

null

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

bhm

2013-12-05T16:26:51Z

false

true

2