LiteFold/GO · Datasets at Hugging Face

GO:1990251

1,990,251

nuclear exosome focus

cellular_component

An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome.

[ "GOC:al", "GOC:vw", "PMID:16823445", "PMID:23980030", "PMID:32012158" ]

null

[ "Mmi1 nuclear focus", "nuclear body" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0016604" ]

[ "has_part GO:0000176" ]

[ "has_part" ]

[ "GO:0000176" ]

[ "GO:0000176", "GO:0016604" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19063\" xsd:anyURI" ]

al

2013-12-09T12:07:46Z

false

true

4

GO:1990252

1,990,252

Syp1 complex

cellular_component

A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis.

[ "GOC:bhm", "PMID:19713939" ]

null

[ "Syp1 dimer" ]

[ "EXACT" ]

[]

[ "GO:0032991" ]

[ "part_of GO:0045334" ]

[ "part_of" ]

[ "GO:0045334" ]

[ "GO:0032991", "GO:0045334" ]

[]

bhm

2013-12-09T14:43:00Z

false

true

3

GO:1990253

1,990,253

cellular response to leucine starvation

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.

[ "PMID:19033384" ]

null

[]

[ "GO:0034198" ]

[]

[ "GO:0034198" ]

[]

al

2013-12-10T11:55:10Z

false

true

7

GO:1990254

1,990,254

keratin filament binding

molecular_function

Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells.

[ "GOC:krc", "PMID:6170061" ]

null

[]

[ "GO:0019215" ]

[]

[ "GO:0019215" ]

[]

tb

2013-12-13T22:05:25Z

false

true

1

GO:1990256

1,990,256

signal clustering

biological_process

Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response.

[ "GOC:als", "PMID:12011072", "PMID:15603739" ]

null

[ "ligand clustering" ]

[ "BROAD" ]

[]

[ "GO:0009966" ]

[]

[ "GO:0009966" ]

[]

tb

2013-12-18T01:13:59Z

false

true

5

GO:1990257

1,990,257

piccolo-bassoon transport vesicle

cellular_component

A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bass...

[ "GOC:dr", "PMID:21569270" ]

null

[ "PTV" ]

[ "RELATED" ]

[]

[ "GO:0030133" ]

[]

[ "GO:0030133" ]

[]

pr

2013-12-19T14:12:09Z

false

true

4

GO:1990258

1,990,258

obsolete histone glutamine methylation

biological_process

OBSOLETE. The modification of a histone by addition of a methyl group to an glutamine residue.

[ "PMID:24352239" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24294\" xsd:anyURI" ]

sp

2014-01-02T15:08:02Z

true

6

GO:1990259

1,990,259

histone H2AQ104 methyltransferase activity

molecular_function

Catalysis of the reaction: L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine + H+. Note that this corresponds to Q105 in yeast.

[ "PMID:24352239", "RHEA:43228" ]

Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes. Note that this resudue is missing from the H2AZ clade. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encod...

[ "histone glutamine methylase activity", "histone glutamine methyltransferase activity", "histone glutamine N-methyltransferase activity", "histone-glutamine methyltransferase activity", "histone-glutamine N-methyltransferase activity" ]

[ "EXACT", "EXACT", "BROAD", "EXACT", "EXACT" ]

[]

[ "RHEA:43228" ]

[ "GO:0036009", "GO:0140940" ]

[]

[ "GO:0036009", "GO:0140940" ]

[]

[ "skos:exactMatch RHEA:43228", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24687\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29860\" xsd:anyURI", ...

sp

2014-01-02T15:10:29Z

false

true

1

GO:1990260

1,990,260

obsolete negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling

biological_process

OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter using a mechanism that involves the localization of a transcription factor and initiated in response to the DNA damage checkpoint signaling.

[ "PMID:24006488" ]

This term was obsoleted because it represents a GO-CAM model.

[]

[ "GO:0000122", "GO:0006974" ]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24817\" xsd:anyURI" ]

al

2014-01-07T17:10:11Z

true

2

GO:1990261

1,990,261

pre-mRNA catabolic process

biological_process

The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA).

[ "GOC:rb", "PMID:22844259" ]

null

[ "pre-mRNA decay", "unspliced RNA decay" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0006401" ]

[]

[ "GO:0006401" ]

[]

rb

2014-01-07T23:06:44Z

false

true

4

GO:1990262

1,990,262

anti-Mullerian hormone receptor signaling pathway

biological_process

The series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Upon ligand binding, the receptor forms a complex consisting of two type II and two type I transmembra...

[ "GOC:hjd", "PMID:23624077" ]

An example of this is Amhr2 in M. musculus (Q8K592) a receptor for anti-mullerian hormone, described in PMID:23624077.

[ "anti-Mullerian hormone signaling pathway" ]

[ "EXACT" ]

[]

[ "GO:0007178" ]

[]

[ "GO:0007178" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26956\" xsd:anyURI" ]

hjd

2014-01-08T20:42:09Z

false

true

9

GO:1990263

1,990,263

obsolete spore wall assembly MAPK cascade

biological_process

OBSOLETE. A MAPK cascade that occurs as a result of deprivation of nourishment.

[ "GOC:al", "PMID:7501024" ]

This term was obsoleted because this pathway is poorly defined.

[ "MAPK cascade in response to starvation", "MAPK cascade involved in nutrient response signaling" ]

[ "EXACT", "EXACT" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26611\" xsd:anyURI" ]

al

2014-01-09T12:27:52Z

true

9

GO:1990264

1,990,264

peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity

biological_process

Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity.

[ "PMID:7501024" ]

null

[]

[ "gocheck_obsoletion_candidate" ]

[]

[ "GO:0035335" ]

[ "part_of GO:0006469" ]

[ "part_of" ]

[ "GO:0006469" ]

[ "GO:0006469", "GO:0035335" ]

[]

al

2014-01-09T14:28:41Z

false

true

7

GO:1990265

1,990,265

platelet-derived growth factor complex

cellular_component

A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes. PDGFs are found in all vertebrates where at least 2 differ...

[ "GOC:bhm", "PMID:11331882" ]

An example of this is PDGFA in human (P04085) in PMID:20534510 (inferred from direct assay).

[ "PDGF complex", "PDGF-AA dimer", "PDGF-AB dimer", "PDGF-BB dimer", "PDGF-CC dimer", "PDGF-DD dimer" ]

[ "RELATED", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW" ]

[]

[ "GO:0036454" ]

[]

[ "GO:0036454" ]

[]

bhm

2014-01-09T16:09:11Z

false

true

6

GO:1990266

1,990,266

neutrophil migration

biological_process

The movement of a neutrophil within or between different tissues and organs of the body.

[ "PMID:1826836" ]

null

[]

[ "GO:0097530" ]

[]

[ "GO:0097530" ]

[]

sl

2014-01-10T00:17:47Z

false

true

8

GO:1990267

1,990,267

response to transition metal nanoparticle

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.

[ "PMID:23150627" ]

null

[ "response to colloidal metal", "response to neutral metal atoms" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:0042221" ]

[]

[ "GO:0042221" ]

[]

sl

2014-01-10T17:16:41Z

false

true

2

GO:1990268

1,990,268

response to gold nanoparticle

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus.

[ "PMID:23150627" ]

null

[]

[ "GO:1990267" ]

[]

[ "GO:1990267" ]

[]

sl

2014-01-10T17:37:34Z

false

true

8

GO:1990269

1,990,269

RNA polymerase II C-terminal domain phosphoserine binding

molecular_function

Binding to phosphorylated serine residues in the C-terminal domain of RNA polymerase II.

[ "GOC:di", "PMID:22796944" ]

null

[ "RNA Pol II C-terminal domain phosphoserine binding", "RNAP II C-terminal domain phosphoserine binding" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0050815", "GO:0099122" ]

[]

[ "GO:0050815", "GO:0099122" ]

[]

tb

2014-01-11T00:34:59Z

false

true

7

GO:1990270

1,990,270

platelet-derived growth factor receptor-ligand complex

cellular_component

A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes and ...

[ "GOC:bhm", "PMID:11331882" ]

An example of this is PDGFA-PGFRA in human (UniProt symbols P04085, P16234) in PMID:7679113 (inferred from direct assay).

[ "PDGF complex", "PDGF receptor-ligand complex", "PDGF-AA-receptor alpha complex", "PDGF-AB-receptor alpha complex", "PDGF-AB-receptor beta complex", "PDGF-BB-receptor alpha complex", "PDGF-BB-receptor alpha-beta complex", "PDGF-BB-receptor beta complex", "PDGF-CC-receptor alpha complex", "PDGF-CC-...

[ "BROAD", "EXACT", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "BROAD" ]

[]

[ "GO:0098797" ]

[ "has_part GO:0043235", "has_part GO:1990265" ]

[ "has_part", "has_part" ]

[ "GO:0043235", "GO:1990265" ]

[ "GO:0043235", "GO:0098797", "GO:1990265" ]

[]

bhm

2014-01-14T11:12:22Z

false

true

5

GO:1990271

1,990,271

obsolete anti-Mullerian hormone

molecular_function

OBSOLETE. Combining with anti-Mullerian hormone to initiate a change in cell activity.

[ "GOC:hjd", "PMID:23624077" ]

An example of this is Amdh2 in M. musculus, UniprotKB:Q8K592-1 in PMID:23624077.

[ "anti-Mullerian hormone" ]

[ "EXACT" ]

[]

hjd

2014-01-14T20:38:39Z

true

9

GO:1990272

1,990,272

anti-Mullerian hormone receptor activity

molecular_function

Combining with anti-Mullerian hormone to initiate a change in cell activity.

[ "GOC:hjd", "PMID:23624077" ]

An example of this is Amdh2 in M. musculus, UniprotKB:Q8K592-1 in PMID:23624077.

[]

[ "GO:0016500" ]

[ "part_of GO:1990262" ]

[ "part_of" ]

[ "GO:1990262" ]

[ "GO:0016500", "GO:1990262" ]

[]

hjd

2014-01-14T21:41:35Z

false

true

6

GO:1990273

1,990,273

snRNA 2,2,7-trimethylguanosine (TMG) capping

biological_process

The sequence of enzymatic reactions by which a 2,2,7-trimethylguanosine cap structure is added to the 5' end of an snRNA. The snRNA capping process includes the formation of 7-methyl-G caps found on all RNA polymerase II transcripts, followed by hypermethylation at the 2' position of the guanosine residue to convert a ...

[ "GOC:vw", "PMID:15590684" ]

null

[ "snRNA 2,2,7-trimethylguanosine (TMG) cap formation", "snRNA 5'-end processing", "snRNA capping" ]

[ "EXACT", "BROAD", "EXACT" ]

[]

[ "GO:0016180", "GO:0036260" ]

[]

[ "GO:0016180", "GO:0036260" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23084\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26940\" xsd:anyURI" ]

al

2014-01-15T15:32:06Z

false

true

2

GO:1990274

1,990,274

obsolete mitotic actomyosin contractile ring disassembly

biological_process

OBSOLETE. Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle.

[ "PMID:14602073", "PMID:22891673" ]

The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using another term

[]

[ "GO:1902404" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26711\" xsd:anyURI" ]

mah

2014-01-16T10:25:42Z

true

1

GO:1990275

1,990,275

preribosome binding

molecular_function

Binding to a preribosome.

[ "GOC:di", "PMID:22735702" ]

null

[]

[ "GO:0043021" ]

[]

[ "GO:0043021" ]

[]

tb

2014-01-16T19:14:50Z

false

true

8

GO:1990276

1,990,276

RNA 5'-gamma-phosphate methyltransferase activity

molecular_function

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule.

[ "GOC:al", "GOC:vw", "PMID:22740346" ]

null

[ "RNA 5'-methyltransferase activity" ]

[ "RELATED" ]

[]

[ "GO:0008171", "GO:0008173", "GO:0008757" ]

[]

[ "GO:0008171", "GO:0008173", "GO:0008757" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26934\" xsd:anyURI" ]

pr

2014-01-28T09:44:16Z

false

true

9

GO:1990277

1,990,277

parasexual reproduction with cellular fusion

biological_process

A type of reproduction in which new individuals are produced from two individuals, with the fusion of two somatic cells.

[ "GOC:di", "PMID:26210747" ]

null

[ "mating", "parasexual conjugation with cellular fusion" ]

[ "BROAD", "EXACT" ]

[]

[ "Wikipedia:Parasexual_cycle" ]

[ "GO:0022414" ]

[ "has_part GO:0140253" ]

[ "has_part" ]

[ "GO:0140253" ]

[ "GO:0022414", "GO:0140253" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22929\" xsd:anyURI" ]

pr

2014-01-28T10:30:20Z

false

true

7

GO:1990278

1,990,278

obsolete positive regulation of MBF transcription factor activity

biological_process

OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor MBF.

[ "PMID:11795845" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "positive regulation of MBF transcription factor activity" ]

[ "EXACT" ]

[]

al

2014-01-29T14:43:44Z

true

5

GO:1990279

1,990,279

obsolete negative regulation of MBF transcription factor activity

biological_process

OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor MBF.

[ "PMID:24006488" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "negative regulation of MBF transcription factor activity" ]

[ "EXACT" ]

[]

al

2014-01-29T14:46:52Z

true

7

GO:1990280

1,990,280

RNA localization to chromatin

biological_process

A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin.

[ "GOC:dos", "GOC:mah", "PMID:22582262" ]

null

[ "RNA localisation to chromatin" ]

[ "EXACT" ]

[]

[ "GO:0006403" ]

[]

[ "GO:0006403" ]

[]

mah

2014-01-30T15:55:34Z

false

true

5

GO:1990281

1,990,281

efflux pump complex

cellular_component

A protein complex that is capable of efflux transmembrane transporter activity.

[ "GOC:dos", "PMID:21556065", "PMID:9417051" ]

null

[ "efflux pump", "efflux transmembrane transporter complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:1902495" ]

[]

[ "GO:1902495" ]

[]

tt

2014-01-31T08:19:53Z

false

true

9

GO:1990294

1,990,294

obsolete peptidyl-threonine trans-autophosphorylation

biological_process

OBSOLETE. The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.

[ "PMID:19357077" ]

This term was obsoleted because it represents a molecular function.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]

al

2014-02-05T12:42:46Z

true

1

GO:1990295

1,990,295

post-anaphase microtubule array

cellular_component

A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center.

[ "PMID:11792817", "PMID:17072892", "PMID:9601091" ]

The best-characterized example is found in the fission yeast Schizosaccharomyces pombe. The eMTOC is cortical, but the post-anaphase array microtubules are not exclusively cortical.

[ "PAA", "post-anaphase array" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0110165" ]

[ "has_part GO:0000923", "part_of GO:0015630" ]

[ "has_part", "part_of" ]

[ "GO:0000923", "GO:0015630" ]

[ "GO:0000923", "GO:0015630", "GO:0110165" ]

[]

mah

2014-02-20T13:54:23Z

false

true

7

GO:1990298

1,990,298

bub1-bub3 complex

cellular_component

Protein complex that associates with the kinetochores.

[ "PMID:22521786" ]

null

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

al

2014-02-26T09:23:04Z

false

true

9

GO:1990299

1,990,299

Bub1-Bub3 complex localization to kinetochore

biological_process

A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore.

[ "PMID:22521786" ]

null

[]

[ "GO:0031503", "GO:0034501" ]

[]

[ "GO:0031503", "GO:0034501" ]

[]

al

2014-02-26T09:29:13Z

false

true

1

GO:1990300

1,990,300

cellulosome binding

molecular_function

Binding to a cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides.

[ "GOC:mengo_curators", "PMID:11893054", "PMID:15197390" ]

null

[ "scaffoldin complex binding" ]

[ "NARROW" ]

[ "GO:1990301" ]

[]

[ "GO:0005488" ]

[]

[ "GO:0005488" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21211\" xsd:anyURI" ]

null

2014-02-26T22:41:22Z

false

true

9

GO:1990302

1,990,302

Bre1-Rad6 ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It ther...

[ "GOC:bhm", "PMID:19531475" ]

This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).

[ "Bre1-Rad6 complex" ]

[ "EXACT" ]

[]

[ "GO:1990234" ]

[ "part_of GO:0005622" ]

[ "part_of" ]

[ "GO:0005622" ]

[ "GO:0005622", "GO:1990234" ]

[]

bhm

2014-02-28T16:50:34Z

false

true

6

GO:1990303

1,990,303

UBR1-RAD6 ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobi...

[ "GOC:bhm", "PMID:19531475" ]

This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).

[ "UBR1-RAD6 complex" ]

[ "EXACT" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

bhm

2014-03-03T21:43:49Z

false

true

1

GO:1990304

1,990,304

MUB1-RAD6-UBR2 ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of ...

[ "GOC:bhm", "PMID:18070918" ]

This complex has been identified in Saccharomyces cerevisiae (UniProt symbol P19812) - see PMID:18070918.

[]

[ "GO:0140535", "GO:1990234" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

bhm

2014-03-03T21:54:21Z

false

true

9

GO:1990305

1,990,305

RAD6-UBR2 ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation.

[ "GOC:bhm", "PMID:15504724" ]

This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:15504724

[ "RAD6-UBR2 complex" ]

[ "EXACT" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

bhm

2014-03-03T22:14:32Z

false

true

3

GO:1990306

1,990,306

RSP5-BUL ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL prote...

[ "GOC:bhm", "PMID:9931424" ]

This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:9931424

[ "RSP5-BUL1 complex", "RSP5-BUL2 complex" ]

[ "EXACT", "RELATED" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

[ "GO:0140535", "GO:1990234" ]

[]

bhm

2014-03-03T22:53:01Z

false

true

7

GO:1990308

1,990,308

type-I dockerin domain binding

molecular_function

Binding to a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain.

[ "GOC:mengo_curators", "PMID:23195689", "PMID:24080387" ]

null

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

tt

2014-03-07T03:10:37Z

false

true

8

GO:1990309

1,990,309

type-II dockerin domain binding

molecular_function

Binding to a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain.

[ "GOC:mengo_curators", "PMID:23195689", "PMID:24080387" ]

null

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

tt

2014-03-07T03:16:49Z

false

true

2

GO:1990310

1,990,310

type-III dockerin domain binding

molecular_function

Binding to a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain.

[ "GOC:mengo_curators", "PMID:23195689", "PMID:24080387" ]

null

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

tt

2014-03-07T03:22:36Z

false

true

7

GO:1990311

1,990,311

type-I cohesin domain binding

molecular_function

Binding to a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain.

[ "GOC:mengo_curators", "PMID:23195689", "PMID:24080387" ]

null

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

tt

2014-03-07T04:47:31Z

false

true

3

GO:1990312

1,990,312

type-II cohesin domain binding

molecular_function

Binding to a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain.

[ "GOC:mengo_curators", "PMID:23195689", "PMID:24080387" ]

null

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

tt

2014-03-07T04:51:07Z

false

true

9

GO:1990313

1,990,313

type-III cohesin domain binding

molecular_function

Binding to a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain.

[ "GOC:mengo_curators", "PMID:23195689", "PMID:24080387" ]

null

[]

[ "GO:0019904" ]

[]

[ "GO:0019904" ]

[]

tt

2014-03-07T04:58:07Z

false

true

2

GO:1990314

1,990,314

cellular response to insulin-like growth factor stimulus

biological_process

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.

[ "PMID:20042609" ]

null

[ "cellular response to insulin-like growth factor" ]

[ "EXACT" ]

[]

[ "GO:0071375" ]

[]

[ "GO:0071375" ]

[]

sl

2014-03-07T19:38:21Z

false

true

4

GO:1990315

1,990,315

Mcs4 RR-MAPKKK complex

cellular_component

A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.

[ "PMID:24255738" ]

In S. pombe it consists of Mpr1, Tdh1, Mcs4, Win1, Wis4 and Wis1.

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

al

2014-03-14T09:59:45Z

false

true

9

GO:1990316

1,990,316

Atg1/ULK1 kinase complex

cellular_component

A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.

[ "GOC:bhm", "GOC:DOS", "GOC:rb", "PMID:15743910", "PMID:19211835", "PMID:19258318", "PMID:19597335", "PMID:22885598" ]

null

[ "ATG1 kinase complex", "ATG1-ATG13 complex", "ATG1/ULK1 signaling complex", "Atg1p signalling complex", "autophagy-initiation complex", "ULK complex", "ULK1 complex", "ULK1 signaling complex", "ULK1-ATG13-FIP200 complex", "ULK1-ATG13-RB1CC1 complex" ]

[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]

[ "GO:0034273", "GO:0070969" ]

[]

[ "GO:1902554" ]

[ "part_of GO:0005737" ]

[ "part_of" ]

[ "GO:0005737" ]

[ "GO:0005737", "GO:1902554" ]

[]

bhm

2014-03-14T10:55:11Z

false

true

9

GO:1990317

1,990,317

Gin4 complex

cellular_component

A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved.

[ "GOC:bhm", "PMID:12058072" ]

null

[ "Gin4-septin complex" ]

[ "EXACT" ]

[]

[ "GO:1902554" ]

[ "part_of GO:0000144" ]

[ "part_of" ]

[ "GO:0000144" ]

[ "GO:0000144", "GO:1902554" ]

[]

bhm

2014-03-14T12:07:05Z

false

true

6

GO:1990318

1,990,318

collagen type XIX trimer

cellular_component

A collagen homotrimer made of three alpha1(XIX) collagen chains, each presenting interrupted triple helical collagen domains. Localizes to basement membrane ECMs, not known to associate with any fibrillar collagens that are predominantly found in the interstitial extracellular matrix.

[ "PMID:10585282", "PMID:12579531", "PMID:12788917", "PMID:17876790", "PMID:31823868", "PMID:35346795", "PMID:9403723" ]

The collagen XIX trimer is often classified as a FACIT collagen trimer (which stands for Fibril Associated Collagens with Interrupted Triple helices) because of the presence of interrupted triple helical collagen domains, similar to other FACIT members. However, evidence show that collagen XIX localizes to basement mem...

[]

[ "GO:0005581", "GO:0140392" ]

[ "part_of GO:0140143" ]

[ "part_of" ]

[ "GO:0140143" ]

[ "GO:0005581", "GO:0140143", "GO:0140392" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29569\" xsd:anyURI" ]

bhm

2014-03-14T16:05:57Z

false

true

6

GO:1990319

1,990,319

collagen type XX trimer

cellular_component

A collagen homotrimer of alpha1(XX) chains.

[ "PMID:17876790" ]

null

[]

[ "GO:0005593" ]

[]

[ "GO:0005593" ]

[]

bhm

2014-03-14T16:31:21Z

false

true

3

GO:1990320

1,990,320

collagen type XXI trimer

cellular_component

A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.

[ "PMID:17876790" ]

null

[]

[ "GO:0005593" ]

[]

[ "GO:0005593" ]

[]

bhm

2014-03-14T16:40:14Z

false

true

3

GO:1990321

1,990,321

collagen type XXII trimer

cellular_component

A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.

[ "PMID:17876790" ]

null

[]

[ "GO:0005593" ]

[]

[ "GO:0005593" ]

[]

bhm

2014-03-14T16:50:05Z

false

true

1

GO:1990322

1,990,322

collagen type XXIII trimer

cellular_component

A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane.

[ "PMID:17876790" ]

null

[]

[ "GO:0030936" ]

[]

[ "GO:0030936" ]

[]

bhm

2014-03-14T22:01:00Z

false

true

1

GO:1990323

1,990,323

collagen type XXIV trimer

cellular_component

A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development.

[ "GOC:bhm", "PMID:17876790" ]

null

[]

[ "GO:0005583" ]

[]

[ "GO:0005583" ]

[]

bhm

2014-03-14T22:05:53Z

false

true

2

GO:1990324

1,990,324

collagen type XXVI trimer

cellular_component

A collagen homotrimer of alpha1(XXVI) chains.

[ "GOC:bhm", "PMID:17876790" ]

null

[]

[ "GO:0005581", "GO:0140392" ]

[ "part_of GO:0140152" ]

[ "part_of" ]

[ "GO:0140152" ]

[ "GO:0005581", "GO:0140152", "GO:0140392" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30146\" xsd:anyURI" ]

bhm

2014-03-16T23:02:35Z

false

true

1

GO:1990325

1,990,325

collagen type XXVII trimer

cellular_component

A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone.

[ "PMID:17876790", "PMID:21421911" ]

null

[]

[ "GO:0005583" ]

[]

[ "GO:0005583" ]

[]

bhm

2014-03-16T23:13:15Z

false

true

5

GO:1990326

1,990,326

collagen type XXVIII trimer

cellular_component

A collagen homotrimer of alpha1(XXVIII) chains.

[ "PMID:17876790" ]

null

[]

[ "GO:0140158", "GO:0140392" ]

[ "part_of GO:0140143" ]

[ "part_of" ]

[ "GO:0140143" ]

[ "GO:0140143", "GO:0140158", "GO:0140392" ]

[]

bhm

2014-03-16T23:15:28Z

false

true

8

GO:1990327

1,990,327

collagen type XXV trimer

cellular_component

A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane.

[ "PMID:17876790" ]

null

[]

[ "GO:0030936" ]

[]

[ "GO:0030936" ]

[]

bhm

2014-03-17T09:28:50Z

false

true

1

GO:1990328

1,990,328

RPB4-RPB7 complex

cellular_component

A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways.

[ "GOC:bhm", "PMID:15591044" ]

null

[ "RNA polymerase II, RPB4-RPB7 subcomplex" ]

[ "NARROW" ]

[]

[ "GO:0140535" ]

[]

[ "GO:0140535" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/10931\" xsd:anyURI" ]

bhm

2014-03-17T09:37:07Z

false

true

5

GO:1990329

1,990,329

IscS-TusA complex

cellular_component

A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.

[ "GOC:bhm", "PMID:20404999" ]

null

[]

[ "GO:1990221" ]

[]

[ "GO:1990221" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27651\" xsd:anyURI" ]

bhm

2014-03-17T10:00:47Z

false

true

6

GO:1990330

1,990,330

IscS-IscU complex

cellular_component

A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consists of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group.

[ "GOC:bhm", "PMID:20404999" ]

null

[]

[ "GO:1990221", "GO:1990229" ]

[]

[ "GO:1990221", "GO:1990229" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27651\" xsd:anyURI" ]

bhm

2014-03-17T10:08:19Z

false

true

1

GO:1990331

1,990,331

Hpa2 acetyltransferase complex

cellular_component

A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer...

[ "GOC:bhm", "PMID:10600387" ]

null

[]

[ "GO:0070775", "GO:1902562" ]

[]

[ "GO:0070775", "GO:1902562" ]

[]

bhm

2014-03-17T10:18:23Z

false

true

1

GO:1990332

1,990,332

Ire1 complex

cellular_component

A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of ...

[ "GOC:bf", "GOC:bhm", "PMID:18191223", "PMID:25437541" ]

An example of this is Ire1 in S. cerevisiae (P32361) in PMID:18191223 (inferred from direct assay).

[ "ER-bound kinase/endoribonuclease (RNase), inositol-requiring enzyme-1", "ERN1 complex", "Ire1 complex dimer", "Ire1 complex homodimer", "Ire1 complex homooligomer", "IRE1 dimer" ]

[ "EXACT", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0098796", "GO:0140534", "GO:1902554", "GO:1902555" ]

[ "part_of GO:0005789" ]

[ "part_of" ]

[ "GO:0005789" ]

[ "GO:0005789", "GO:0098796", "GO:0140534", "GO:1902554", "GO:1902555" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26879\" xsd:anyURI" ]

bhm

2014-03-17T10:46:58Z

false

true

1

GO:1990333

1,990,333

mitotic checkpoint complex, CDC20-MAD2 subcomplex

cellular_component

A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.

[ "GOC:bhm", "PMID:15879521" ]

An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay).

[ "CDC20-MAD2 complex" ]

[ "EXACT" ]

[]

[ "GO:0140513" ]

[ "part_of GO:0033597" ]

[ "part_of" ]

[ "GO:0033597" ]

[ "GO:0033597", "GO:0140513" ]

[]

bhm

2014-03-17T14:11:35Z

false

true

5

GO:1990334

1,990,334

Bfa1-Bub2 complex

cellular_component

A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN ac...

[ "GOC:bhm", "PMID:16449187" ]

null

[]

[ "GO:1902773" ]

[ "part_of GO:0005816" ]

[ "part_of" ]

[ "GO:0005816" ]

[ "GO:0005816", "GO:1902773" ]

[]

bhm

2014-03-17T14:34:21Z

false

true

1

GO:1990339

1,990,339

laminin-522 trimer

cellular_component

A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains.

[ "PMID:15979864", "PMID:21421915", "PMID:23263632" ]

null

[ "laminin-522", "laminin-522 complex" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0043256" ]

[]

[ "GO:0043256" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30807\" xsd:anyURI" ]

bhm

2014-03-20T23:41:32Z

false

true

5

GO:1990340

1,990,340

laminin-523 trimer

cellular_component

A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains.

[ "PMID:15979864", "PMID:21421915", "PMID:23263632" ]

null

[ "laminin-15 complex", "laminin-523" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0043256" ]

[]

[ "GO:0043256" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30807\" xsd:anyURI" ]

bhm

2014-03-20T23:48:25Z

false

true

9

GO:1990341

1,990,341

thrombospondin complex

cellular_component

A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour.

[ "GOC:bhm", "PMID:15094109", "PMID:18193164" ]

null

[]

[ "GO:0140392" ]

[ "part_of GO:0140149" ]

[ "part_of" ]

[ "GO:0140149" ]

[ "GO:0140149", "GO:0140392" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31065\" xsd:anyURI" ]

bhm

2014-03-21T14:27:07Z

false

true

8

GO:1990342

1,990,342

heterochromatin island

cellular_component

A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi.

[ "PMID:22144463", "PMID:24210919" ]

An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin islands are formed at meiotic genes during vegetative (mitotic) growth.

[]

[ "GO:0000792" ]

[]

[ "GO:0000792" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11247\" xsd:anyURI" ]

mah

2014-03-21T15:26:44Z

false

true

2

GO:1990344

1,990,344

secondary cell septum biogenesis

biological_process

A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division.

[ "PMID:22891259" ]

null

[]

[ "GO:0044085", "GO:1902410" ]

[ "part_of GO:0140278" ]

[ "part_of" ]

[ "GO:0140278" ]

[ "GO:0044085", "GO:0140278", "GO:1902410" ]

[]

mah

2014-03-24T13:24:48Z

false

true

2

GO:1990346

1,990,346

BID-BCL-xl complex

cellular_component

A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.

[ "GOC:bhm", "PMID:14634621" ]

null

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

bhm

2014-03-25T00:18:41Z

false

true

3

GO:1990347

1,990,347

obsolete G*/A mismatch-specific adenine-DNA glycosylase activity

molecular_function

OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite 8-oxoG in the template by adenine DNA glycosylase activity. The reaction leaves an apyrimidinic (AP) site.

[ "PMID:24559510" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "G*/A mismatch-specific adenine-DNA glycosylase activity" ]

[ "EXACT" ]

[]

al

2014-03-25T10:14:37Z

true

9

GO:1990348

1,990,348

obsolete G/A mismatch specific adenine DNA glycosylase activity

molecular_function

OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite guanine in the template by adenine DNA glycosylase activity. The reaction leaves an apurinic AP site. I also requested same term but for Go/A mismatch. If you think it is better to make one term for mismatched adenine that is fine by...

[ "PMID:9737967" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "G/A mismatch specific adenine DNA glycosylase activity" ]

[ "EXACT" ]

[]

al

2014-03-25T10:55:45Z

true

5

GO:1990349

1,990,349

gap junction-mediated intercellular transport

biological_process

The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells.

[ "GOC:hjd", "PMID:14506308", "PMID:23261543", "Wikipedia:Gap_junction" ]

null

[]

[ "GO:0010496" ]

[]

[ "GO:0010496" ]

[]

hjd

2014-03-25T18:05:44Z

false

true

8

GO:1990350

1,990,350

glucose transporter complex

cellular_component

A protein complex facilitating glucose transport into, out of or within a cell, or between cells.

[ "GOC:bhm", "PMID:15449578" ]

An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).

[]

[ "GO:1990351" ]

[]

[ "GO:1990351" ]

[]

bhm

2014-03-26T14:12:05Z

false

true

7

GO:1990351

1,990,351

transporter complex

cellular_component

A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.

[ "GOC:bhm", "PMID:15449578" ]

An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).

[]

[ "GO:0032991" ]

[]

[ "GO:0032991" ]

[]

bhm

2014-03-26T14:23:27Z

false

true

5

GO:1990352

1,990,352

BRE1 E3 ubiquitin ligase complex

cellular_component

A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes.

[ "GOC:bhm", "PMID:19531475" ]

An example of this is BRE1 in Saccharomyces cerevisiae (UniProt symbol Q07457) in PMID:19531475 (inferred from direct assay).

[ "BRE1 E3 ubiquitin-protein ligase complex", "BRE1 oligomer" ]

[ "EXACT", "EXACT" ]

[]

[ "GO:0000151" ]

[]

[ "GO:0000151" ]

[]

bhm

2014-03-27T13:49:05Z

false

true

1

GO:1990353

1,990,353

Fused-Smurf ubiquitin ligase complex

cellular_component

A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation.

[ "GOC:bhm", "PMID:21145463" ]

An example of this is FUSED in Drosophila melanogaster (UniProt symbol P23647) in PMID:21145463 (inferred from direct assay).

[]

[ "GO:0000151" ]

[]

[ "GO:0000151" ]

[]

bhm

2014-03-27T14:02:09Z

false

true

2

GO:1990354

1,990,354

activated SUMO-E1 ligase complex

cellular_component

A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins.

[ "GOC:bhm", "PMID:15660128" ]

An example of this is SAE1 in human (UniProt symbol Q9UBE0) in PMID:15660128 (inferred from direct assay).

[ "SUMO-SAE1/2 complex" ]

[ "NARROW" ]

[]

[ "GO:0106068", "GO:0140513" ]

[ "has_part GO:0031510" ]

[ "has_part" ]

[ "GO:0031510" ]

[ "GO:0031510", "GO:0106068", "GO:0140513" ]

[]

bhm

2014-03-31T13:22:45Z

false

true

4

GO:1990355

1,990,355

obsolete L-methionine salvage from methionine sulphoxide

biological_process

OBSOLETE. The generation of L-methionine from methionine sulphoxide.

[ "PMID:24118096" ]

The reason for obsoletion is that the term represents a single step process and is not generally considered a salvage process.

[ "methionine salvage from methionine sulphoxide" ]

[ "BROAD" ]

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29900\" xsd:anyURI" ]

al

2014-04-02T12:55:01Z

true

1

GO:1990356

1,990,356

obsolete sumoylated E2 ligase complex

cellular_component

OBSOLETE. A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligas...

[ "GOC:bhm", "PMID:18691969" ]

This term was obsoleted because it is represents a complex with a modified (sumoylated) subunit; this is out of the scope of GO.

[]

[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/21011\" xsd:anyURI" ]

bhm

2014-04-02T14:06:56Z

true

3

GO:1990357

1,990,357

terminal web

cellular_component

An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure ...

[ "GOC:kmv", "PMID:19437512", "PMID:24677443", "PMID:7511618", "Wikipedia:Terminal_web" ]

null

[]

[ "GO:0030864" ]

[]

[ "GO:0030864" ]

[]

pr

2014-04-03T14:29:59Z

false

true

4

GO:1990358

1,990,358

xylanosome

cellular_component

A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose.

[ "GOC:mengo_curators", "PMID:16769147" ]

null

[ "xylanolytic complex" ]

[ "EXACT" ]

[]

[ "GO:1902494" ]

[]

[ "GO:1902494" ]

[]

tt

2014-04-05T18:08:54Z

false

true

7

GO:1990359

1,990,359

stress response to zinc ion

biological_process

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.

[ "GOC:kmv", "PMID:17888400" ]

null

[ "response to zinc ion stress", "response to zinc toxicity", "stress response to zinc" ]

[ "EXACT", "RELATED", "BROAD" ]

[]

[ "GO:0010043", "GO:0097501" ]

[]

[ "GO:0010043", "GO:0097501" ]

[]

kmv

2014-04-14T15:54:05Z

false

true

5

GO:1990360

1,990,360

PKM2 protein kinase complex

cellular_component

A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer.

[ "GOC:bhm", "PMID:24606918" ]

null

[ "PKM2-SAICAR complex", "PKM2-SAICAR protein kinase complex" ]

[ "RELATED", "RELATED" ]

[]

[ "GO:1902911" ]

[]

[ "GO:1902911" ]

[]

bhm

2014-04-17T14:03:36Z

false

true

6

GO:1990361

1,990,361

PKM2 pyruvate kinase complex

cellular_component

A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013).

[ "GOC:bhm", "PMID:24606918" ]

An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).

[ "PKM2 homotetramer" ]

[ "EXACT" ]

[]

[ "GO:1902912" ]

[]

[ "GO:1902912" ]

[]

bhm

2014-04-17T14:16:24Z

false

true

9

GO:1990362

1,990,362

butanol dehydrogenase (NAD+) activity

molecular_function

Catalysis of the reaction: butan-1-ol + NAD+ = butanal + H+ + NADH.

[ "GOC:mengo_curators", "PMID:1999395", "RHEA:33199" ]

null

[ "butanol dehydrogenase activity" ]

[ "BROAD" ]

[]

[ "RHEA:33199" ]

[ "GO:0004022" ]

[]

[ "GO:0004022" ]

[]

[ "skos:exactMatch RHEA:33199", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27136\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]

tt

2014-04-23T21:14:09Z

false

true

8

GO:1990363

1,990,363

obsolete response to hydrolysate

biological_process

OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of hydrolysate (any product of hydrolysis).

[ "GOC:mengo_curators", "PMID:23356676" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "response to hydrolysate" ]

[ "EXACT" ]

[]

tt

2014-04-23T22:12:24Z

true

9

GO:1990364

1,990,364

obsolete response to aldehyde

biological_process

OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde.

[ "GOC:mengo_curators", "PMID:23356676" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "response to aldehyde" ]

[ "EXACT" ]

[]

tt

2014-04-23T22:18:04Z

true

5

GO:1990365

1,990,365

obsolete response to phenol

biological_process

OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phenols.

[ "GOC:mengo_curators", "PMID:23356676" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "response to phenol" ]

[ "EXACT" ]

[]

tt

2014-04-23T22:20:00Z

true

2

GO:1990366

1,990,366

obsolete response to organic acid

biological_process

OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic acid.

[ "GOC:mengo_curators", "PMID:23356676" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "response to organic acid" ]

[ "EXACT" ]

[]

tt

2014-04-23T22:21:26Z

true

5

GO:1990368

1,990,368

obsolete process resulting in tolerance to hydrolysate

biological_process

OBSOLETE. A response that results in a state of tolerance to hydrolysate (product of hydrolysis).

[ "GOC:mengo_curators", "PMID:23356676" ]

This term was obsoleted at the TermGenie Gatekeeper stage.

[ "process resulting in tolerance to hydrolysate" ]

[ "EXACT" ]

[]

tt

2014-04-23T22:27:51Z

true

1

GO:1990370

1,990,370

obsolete process resulting in tolerance to aldehyde

biological_process

OBSOLETE. A response that results in a state of tolerance to aldehyde.

[ "GOC:mengo_curators", "PMID:23356676" ]

This term was obsoleted because it does not represent a clear process.

[]

tt

2014-04-23T22:30:50Z

true

5

GO:1990371

1,990,371

obsolete process resulting in tolerance to phenol

biological_process

OBSOLETE. A response that results in a state of tolerance to phenol.

[ "GOC:mengo_curators", "PMID:23356676" ]

This term was obsoleted because it does not represent a clear process.

[]

tt

2014-04-23T22:32:48Z

true

3

GO:1990372

1,990,372

obsolete process resulting in tolerance to organic acid

biological_process

OBSOLETE. A response that results in a state of tolerance to organic acid.

[ "GOC:mengo_curators", "PMID:23356676" ]

This term was obsoleted because it does not represent a clear process.

[]

tt

2014-04-23T22:34:12Z

true

1

GO:1990375

1,990,375

baculum development

biological_process

The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure.

[ "GOC:sl", "PMID:21471296" ]

null

[ "os penis development", "penile bone development", "penis bone development" ]

[ "EXACT", "EXACT", "EXACT" ]

[]

[ "GO:0048608" ]

[]

[ "GO:0048608" ]

[]

sl

2014-05-01T23:59:13Z

false

true

5

GO:1990376

1,990,376

obsolete negative regulation of G1/S transition of mitotic cell cycle by positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation

biological_process

OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation that results in negative regulation of mitotic G1/S transition.

[ "PMID:9135083" ]

This term was made obsolete because it would not be used for annotation.

[]

al

2014-05-07T08:51:19Z

true

2

GO:1990377

1,990,377

organomineral extracellular matrix

cellular_component

An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight.

[ "GOC:jh2", "PMID:15994301" ]

An example is found in shell calcitic prisms of the Mediterranean fan mussel Pinna nobilis (PMID:15994301), but the term may also be useful to annotate bone and eggshell proteins.

[]

[ "GO:0140047" ]

[]

[ "GO:0140047" ]

[]

pr

2014-05-07T10:02:28Z

false

true

6