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GO

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go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0007000
7,000
nucleolus organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.
[ "GOC:dph", "GOC:jid", "GOC:jl", "GOC:mah" ]
null
[ "nucleolus organisation", "nucleolus organization and biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0006997" ]
[]
[]
[]
[ "GO:0006997" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007002
7,002
obsolete centromere binding
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:curators" ]
This term was made obsolete because it represents a molecular function and not a biological process.
[ "centromere binding" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0019237" ]
[]
[]
null
null
true
true
1
GO:0007004
7,004
telomere maintenance via telomerase
biological_process
The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.
[ "GOC:elh" ]
null
[ "telomerase-dependent telomere maintenance" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-171319 \"Telomere Extension By Telomerase\"" ]
[ "GO:0006278", "GO:0010833" ]
[ "has_part GO:0003720", "has_part GO:1905324" ]
[ "has_part", "has_part" ]
[ "GO:0003720", "GO:1905324" ]
[ "GO:0003720", "GO:0006278", "GO:0010833", "GO:1905324" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0007005
7,005
mitochondrion organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
[ "GOC:dph", "GOC:jl", "GOC:mah", "GOC:sgd_curators", "PMID:9786946" ]
null
[ "mitochondria organization", "mitochondrial biogenesis", "mitochondrial organization", "mitochondrion biogenesis", "mitochondrion morphogenesis", "mitochondrion organisation", "mitochondrion organization and biogenesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "RELATED", "EXACT", "RELATED" ]
[]
[ "goslim_chembl", "goslim_drosophila", "goslim_generic", "goslim_pir", "goslim_pombe", "goslim_yeast" ]
[ "Reactome:R-HSA-1592230 \"Mitochondrial biogenesis\"" ]
[ "GO:0006996" ]
[]
[]
[]
[ "GO:0006996" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0007006
7,006
mitochondrial membrane organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
[ "GOC:ai", "GOC:dph", "GOC:jl", "GOC:mah" ]
null
[ "mitochondrial membrane organisation", "mitochondrial membrane organization and biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0007005", "GO:0061024" ]
[ "occurs_in GO:0005739" ]
[ "occurs_in" ]
[ "GO:0005739" ]
[ "GO:0005739", "GO:0007005", "GO:0061024" ]
[ "GO:0061024", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007007
7,007
inner mitochondrial membrane organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane.
[ "GOC:ai", "GOC:dph", "GOC:jl", "GOC:mah" ]
See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.
[ "inner mitochondrial membrane organisation", "inner mitochondrial membrane organization and biogenesis", "mitochondrial inner membrane organization" ]
[ "EXACT", "RELATED", "EXACT" ]
[]
[]
[]
[ "GO:0007006" ]
[]
[]
[]
[ "GO:0007006" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007008
7,008
outer mitochondrial membrane organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane.
[ "GOC:ai", "GOC:dph", "GOC:jl", "GOC:mah" ]
See also the cellular component term 'mitochondrial outer membrane ; GO:0005741'.
[ "outer mitochondrial membrane organisation", "outer mitochondrial membrane organization and biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0007006" ]
[]
[]
[]
[ "GO:0007006" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0007009
7,009
plasma membrane organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
[ "GOC:dph", "GOC:jl", "GOC:mah" ]
null
[ "plasma membrane organisation", "plasma membrane organization and biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[ "goslim_chembl" ]
[]
[ "GO:0061024" ]
[ "part_of GO:0010256" ]
[ "part_of" ]
[ "GO:0010256" ]
[ "GO:0010256", "GO:0061024" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007010
7,010
cytoskeleton organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
[ "GOC:dph", "GOC:jl", "GOC:mah" ]
null
[ "cytoskeletal organization and biogenesis", "cytoskeletal regulator activity", "cytoskeleton organisation", "cytoskeleton organization and biogenesis" ]
[ "RELATED", "RELATED", "EXACT", "RELATED" ]
[]
[ "goslim_candida", "goslim_chembl", "goslim_drosophila", "goslim_generic", "goslim_prokaryote", "goslim_yeast" ]
[]
[ "GO:0006996" ]
[]
[]
[]
[ "GO:0006996" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0007014
7,014
actin ubiquitination
biological_process
The modification of actin by addition of ubiquitin groups.
[ "GOC:mah" ]
null
[ "indirect flight muscle actin ubiquitination" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0016567", "GO:0030047" ]
[]
[]
[]
[ "GO:0016567", "GO:0030047" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0007015
7,015
actin filament organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or...
[ "GOC:mah" ]
null
[ "actin filament organisation", "regulation of actin filament localization" ]
[ "EXACT", "NARROW" ]
[]
[]
[]
[ "GO:0097435" ]
[ "part_of GO:0030036" ]
[ "part_of" ]
[ "GO:0030036" ]
[ "GO:0030036", "GO:0097435" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0007016
7,016
obsolete cytoskeletal anchoring at plasma membrane
biological_process
OBSOLETE. A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.
[ "ISBN:0198599323" ]
This term was obsoleted because it represents a molecular function.
[ "cytoskeletal anchoring activity" ]
[ "RELATED" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0007010", "GO:0106006" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19119\" xsd:anyURI" ]
null
null
true
true
6
GO:0007017
7,017
microtubule-based process
biological_process
Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
[ "GOC:mah" ]
null
[]
[]
[]
[ "goslim_chembl" ]
[]
[ "GO:0009987" ]
[]
[]
[]
[ "GO:0009987" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19809\" xsd:anyURI" ]
null
null
false
true
7
GO:0007018
7,018
microtubule-based movement
biological_process
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
[ "GOC:cjm", "ISBN:0815316194" ]
null
[]
[]
[]
[ "goslim_drosophila", "goslim_generic" ]
[ "Reactome:R-HSA-983189 \"Kinesins\"" ]
[ "GO:0007017" ]
[]
[]
[]
[ "GO:0007017" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0007019
7,019
microtubule depolymerization
biological_process
The removal of tubulin heterodimers from one or both ends of a microtubule.
[ "ISBN:0815316194" ]
null
[ "microtubule catastrophe", "microtubule depolymerization during nuclear congression", "microtubule disassembly", "microtubule shortening" ]
[ "NARROW", "NARROW", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0031109", "GO:0051261", "GO:0097435" ]
[]
[]
[]
[ "GO:0031109", "GO:0051261", "GO:0097435" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0007020
7,020
microtubule nucleation
biological_process
The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
[ "GOC:curators", "ISBN:0815316194", "PMID:12517712" ]
null
[]
[]
[]
[]
[ "Wikipedia:Microtubule_nucleation" ]
[ "GO:0000226" ]
[ "part_of GO:0046785" ]
[ "part_of" ]
[ "GO:0046785" ]
[ "GO:0000226", "GO:0046785" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0007023
7,023
post-chaperonin tubulin folding pathway
biological_process
Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors.
[ "PMID:10542094" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-389977 \"Post-chaperonin tubulin folding pathway\"" ]
[ "GO:0006457" ]
[]
[]
[]
[ "GO:0006457" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0007026
7,026
negative regulation of microtubule depolymerization
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing d...
[ "GOC:mah", "ISBN:0815316194" ]
null
[ "down regulation of microtubule depolymerization", "down-regulation of microtubule depolymerization", "downregulation of microtubule depolymerization", "inhibition of microtubule depolymerization", "microtubule rescue", "microtubule stabilization", "negative regulation of microtubule catastrophe", "ne...
[ "EXACT", "EXACT", "EXACT", "NARROW", "NARROW", "EXACT", "NARROW", "EXACT" ]
[]
[]
[]
[ "GO:0031111", "GO:0031114", "GO:1901880", "GO:1902904" ]
[ "negatively_regulates GO:0007019" ]
[ "negatively_regulates" ]
[ "GO:0007019" ]
[ "GO:0007019", "GO:0031111", "GO:0031114", "GO:1901880", "GO:1902904" ]
[ "GO:0065007", "negatively_regulates GO:0007019" ]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0007027
7,027
negative regulation of axonemal microtubule depolymerization
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.
[ "GOC:dph", "GOC:mah" ]
null
[ "axonemal microtubule stabilization", "negative regulation of microtubule depolymerization in axoneme" ]
[ "EXACT", "RELATED" ]
[]
[]
[]
[ "GO:0007026", "GO:0010937", "GO:0031345", "GO:0120035" ]
[ "negatively_regulates GO:0060404" ]
[ "negatively_regulates" ]
[ "GO:0060404" ]
[ "GO:0007026", "GO:0010937", "GO:0031345", "GO:0060404", "GO:0120035" ]
[ "GO:0065007", "negatively_regulates GO:0060404" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007028
7,028
cytoplasm organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
[ "GOC:curators", "GOC:dph", "GOC:jl", "GOC:mah" ]
null
[ "cytoplasm organisation", "cytoplasm organization and biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[ "goslim_pir" ]
[]
[ "GO:0016043" ]
[]
[]
[]
[ "GO:0016043" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007029
7,029
endoplasmic reticulum organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
[ "GOC:dph", "GOC:jl", "GOC:mah" ]
null
[ "endoplasmic reticulum morphology", "endoplasmic reticulum organisation", "endoplasmic reticulum organization and biogenesis", "ER organisation", "ER organization and biogenesis" ]
[ "RELATED", "EXACT", "RELATED", "EXACT", "RELATED" ]
[]
[ "goslim_pir" ]
[]
[ "GO:0006996" ]
[ "part_of GO:0010256" ]
[ "part_of" ]
[ "GO:0010256" ]
[ "GO:0006996", "GO:0010256" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0007031
7,031
peroxisome organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
[ "GOC:mah" ]
null
[ "peroxisome organisation", "peroxisome organization and biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[ "goslim_drosophila", "goslim_generic", "goslim_pir", "goslim_pombe", "goslim_yeast" ]
[]
[ "GO:0006996" ]
[]
[]
[]
[ "GO:0006996" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007032
7,032
endosome organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
[ "GOC:dph", "GOC:jl", "GOC:mah" ]
null
[ "endosome organisation", "endosome organization and biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[ "goslim_pir" ]
[]
[ "GO:0016050" ]
[ "part_of GO:0010256" ]
[ "part_of" ]
[ "GO:0010256" ]
[ "GO:0010256", "GO:0016050" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007033
7,033
vacuole organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
[ "GOC:mah" ]
null
[ "vacuolar assembly", "vacuole biogenesis", "vacuole organisation", "vacuole organization and biogenesis" ]
[ "NARROW", "RELATED", "EXACT", "RELATED" ]
[ "GO:0044086" ]
[ "goslim_drosophila", "goslim_pir", "goslim_yeast" ]
[]
[ "GO:0006996" ]
[]
[]
[]
[ "GO:0006996" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007035
7,035
vacuolar acidification
biological_process
Any process that reduces the pH of the vacuole, corresponding to an increase in hydrogen ion concentration.
[ "GOC:jid" ]
null
[]
[]
[]
[]
[]
[ "GO:0051452" ]
[]
[]
[]
[ "GO:0051452" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0007036
7,036
vacuolar calcium ion homeostasis
biological_process
Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.
[ "GOC:ai", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0006874" ]
[ "occurs_in GO:0005773" ]
[ "occurs_in" ]
[ "GO:0005773" ]
[ "GO:0005773", "GO:0006874" ]
[ "GO:0055074", "occurs_in GO:0005773" ]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0007038
7,038
endocytosed protein transport to vacuole
biological_process
The directed movement of proteins imported into a cell by endocytosis to the vacuole.
[ "GOC:ai" ]
See also the biological process term 'endocytosis ; GO:0006897'.
[ "delivery of endocytosed proteins to the vacuole" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006886", "GO:0007034" ]
[]
[]
[]
[ "GO:0006886", "GO:0007034" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0007039
7,039
protein catabolic process in the vacuole
biological_process
The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.
[ "GOC:mah", "GOC:vw" ]
null
[ "vacuolar protein breakdown", "vacuolar protein catabolic process", "vacuolar protein catabolism", "vacuolar protein degradation" ]
[ "RELATED", "RELATED", "RELATED", "RELATED" ]
[]
[]
[]
[ "GO:0030163" ]
[ "occurs_in GO:0005773" ]
[ "occurs_in" ]
[ "GO:0005773" ]
[ "GO:0005773", "GO:0030163" ]
[ "GO:0030163", "occurs_in GO:0005773" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0007040
7,040
lysosome organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
[ "GOC:mah" ]
null
[ "lysosome organisation", "lysosome organization and biogenesis" ]
[ "EXACT", "RELATED" ]
[]
[ "goslim_generic" ]
[]
[ "GO:0080171" ]
[]
[]
[]
[ "GO:0080171" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0007041
7,041
lysosomal transport
biological_process
The directed movement of substances into, out of or within a lysosome.
[ "GOC:ai" ]
null
[]
[]
[]
[]
[]
[ "GO:0007034" ]
[]
[]
[]
[ "GO:0007034" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007042
7,042
lysosomal lumen acidification
biological_process
Any process that reduces the pH of the lysosomal lumen, corresponding to an increase in hydrogen ion concentration.
[ "GOC:jid" ]
null
[ "lysosome pH reduction" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007035" ]
[]
[]
[]
[ "GO:0007035" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0007043
7,043
cell-cell junction assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form a junction between cells.
[ "GOC:ai" ]
null
[ "intercellular junction assembly" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0034329", "GO:0045216" ]
[]
[]
[]
[ "GO:0034329", "GO:0045216" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0007044
7,044
cell-substrate junction assembly
biological_process
The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.
[ "GOC:mah" ]
The primary label for merged term was 'cell-substrate adherens junction assembly' GO:0007045. The term was merged into the parent 'cell-substrate junction assembly', because, based on the most recent litarature, 'adherens junction' is always a 'cell-cell junction' (PMID:20571587, PMID:17854762, PMID:21422226, PMID:2809...
[ "cell-substrate adherens junction assembly" ]
[ "RELATED" ]
[ "GO:0007045" ]
[]
[]
[ "GO:0034329", "GO:0150115" ]
[]
[]
[]
[ "GO:0034329", "GO:0150115" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007048
7,048
obsolete oncogenesis
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:curators" ]
This term was made obsolete because it represents a pathological process.
[ "oncogenesis" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
2
GO:0007049
7,049
cell cycle
biological_process
The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells n...
[ "GOC:curators", "GOC:mtg_cell_cycle" ]
null
[ "cell-division cycle" ]
[ "EXACT" ]
[]
[ "gocheck_do_not_annotate", "goslim_agr", "goslim_candida", "goslim_chembl", "goslim_flybase_ribbon", "goslim_pir", "goslim_plant", "goslim_plant_ribbon" ]
[ "Reactome:R-HSA-1640170 \"Cell Cycle\"", "Wikipedia:Cell_cycle" ]
[ "GO:0009987" ]
[]
[]
[]
[ "GO:0009987" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0007051
7,051
spindle organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosom...
[ "GOC:curators", "GOC:mah" ]
null
[ "spindle organisation", "spindle organization and biogenesis", "spindle stabilization" ]
[ "EXACT", "RELATED", "RELATED" ]
[ "GO:0043146" ]
[]
[]
[ "GO:0000226", "GO:0022402" ]
[]
[]
[]
[ "GO:0000226", "GO:0022402" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007052
7,052
mitotic spindle organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
[ "GOC:curators", "GOC:mah" ]
In fission yeast most mitotic spindle organization occurs in the nucleus.
[ "mitotic spindle organisation", "mitotic spindle organisation in nucleus", "mitotic spindle organization and biogenesis", "mitotic spindle organization and biogenesis in cell nucleus", "mitotic spindle organization and biogenesis in nucleus", "mitotic spindle organization in nucleus", "mitotic spindle s...
[ "EXACT", "NARROW", "RELATED", "NARROW", "NARROW", "NARROW", "RELATED", "EXACT", "NARROW" ]
[ "GO:0000071", "GO:0030472", "GO:0043148" ]
[]
[ "Reactome:R-HSA-9648025 \"EML4 and NUDC in mitotic spindle formation\"" ]
[ "GO:0007051", "GO:1902850" ]
[]
[]
[]
[ "GO:0007051", "GO:1902850" ]
[ "GO:0007051", "part_of GO:0000278" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15341\" xsd:anyURI" ]
null
null
false
true
3
GO:0007053
7,053
spindle assembly involved in male meiosis
biological_process
The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0090306" ]
[ "part_of GO:0007140" ]
[ "part_of" ]
[ "GO:0007140" ]
[ "GO:0007140", "GO:0090306" ]
[ "GO:0051225", "part_of GO:0007140" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0007055
7,055
spindle assembly involved in male meiosis II
biological_process
The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
[ "GOC:mah" ]
null
[ "male meiosis II spindle assembly" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0007053" ]
[ "part_of GO:0007142" ]
[ "part_of" ]
[ "GO:0007142" ]
[ "GO:0007053", "GO:0007142" ]
[ "GO:0051225", "part_of GO:0007142" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007056
7,056
spindle assembly involved in female meiosis
biological_process
The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
[ "GOC:mah" ]
null
[ "female meiotic spindle assembly" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0090306" ]
[ "part_of GO:0007143" ]
[ "part_of" ]
[ "GO:0007143" ]
[ "GO:0007143", "GO:0090306" ]
[ "GO:0051225", "part_of GO:0007143" ]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0007057
7,057
spindle assembly involved in female meiosis I
biological_process
The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
[ "GOC:mah" ]
null
[ "female meiosis I spindle assembly" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0007056" ]
[ "part_of GO:0007144" ]
[ "part_of" ]
[ "GO:0007144" ]
[ "GO:0007056", "GO:0007144" ]
[ "GO:0051225", "part_of GO:0007144" ]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007058
7,058
spindle assembly involved in female meiosis II
biological_process
The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
[ "GOC:mah" ]
null
[ "female meiosis II spindle assembly" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0007056" ]
[ "part_of GO:0007147" ]
[ "part_of" ]
[ "GO:0007147" ]
[ "GO:0007056", "GO:0007147" ]
[ "GO:0051225", "part_of GO:0007147" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0007059
7,059
chromosome segregation
biological_process
The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have co...
[ "GOC:jl", "GOC:mah", "GOC:mtg_cell_cycle", "GOC:vw" ]
null
[ "chromosome division", "chromosome transmission" ]
[ "EXACT", "RELATED" ]
[]
[ "goslim_chembl", "goslim_drosophila", "goslim_generic", "goslim_pir", "goslim_prokaryote", "goslim_yeast" ]
[ "Wikipedia:Chromosome_segregation" ]
[ "GO:0022402" ]
[]
[]
[]
[ "GO:0022402" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007060
7,060
male meiosis chromosome segregation
biological_process
The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.
[ "GOC:ai" ]
null
[]
[]
[]
[]
[]
[ "GO:0045132" ]
[ "part_of GO:0007140" ]
[ "part_of" ]
[ "GO:0007140" ]
[ "GO:0007140", "GO:0045132" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0007063
7,063
regulation of sister chromatid cohesion
biological_process
Any process that modulates the frequency, rate or extent of sister chromatid cohesion.
[ "GOC:curators" ]
null
[]
[]
[]
[]
[]
[ "GO:0010564", "GO:0033044" ]
[ "regulates GO:0007062" ]
[ "regulates" ]
[ "GO:0007062" ]
[ "GO:0007062", "GO:0010564", "GO:0033044" ]
[ "GO:0065007", "regulates GO:0007062" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007064
7,064
mitotic sister chromatid cohesion
biological_process
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
[ "GOC:ai", "GOC:rn", "PMID:10827941", "PMID:11389843", "PMID:14623866" ]
null
[]
[]
[]
[]
[]
[ "GO:0007062" ]
[]
[]
[]
[ "GO:0007062" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0007065
7,065
male meiosis sister chromatid cohesion
biological_process
The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male.
[ "GOC:ai" ]
null
[]
[]
[]
[]
[]
[ "GO:0051177" ]
[]
[]
[]
[ "GO:0051177" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0007066
7,066
female meiosis sister chromatid cohesion
biological_process
The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female.
[ "GOC:ai" ]
null
[]
[]
[]
[]
[]
[ "GO:0051177" ]
[]
[]
[]
[ "GO:0051177" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007068
7,068
obsolete negative regulation of transcription during mitotic cell cycle
biological_process
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.
[ "GOC:curators" ]
The reason for obsoletion is that 'during' should be captured using an annotation extension.
[ "down regulation of transcription during mitosis", "down-regulation of transcription during mitosis", "downregulation of transcription during mitosis", "inhibition of transcription during mitosis", "mitotic repression of transcription", "negative regulation of transcription, mitotic" ]
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000122", "GO:0044772" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14896\" xsd:anyURI" ]
null
null
true
true
6
GO:0007069
7,069
obsolete negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle
biological_process
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.
[ "GOC:curators" ]
The reason for obsoletion is that 'during' should be captured using an annotation extension.
[ "down regulation of transcription from RNA polymerase I promoter during mitosis", "down-regulation of transcription from RNA polymerase I promoter during mitosis", "downregulation of transcription from RNA polymerase I promoter during mitosis", "inhibition of transcription from RNA polymerase I promoter durin...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0016479", "GO:0044772" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14896\" xsd:anyURI" ]
null
null
true
true
9
GO:0007070
7,070
obsolete negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle
biological_process
OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.
[ "GOC:curators" ]
The reason for obsoletion is that 'during' should be captured using an annotation extension.
[ "down regulation of transcription from RNA polymerase II promoter during mitosis", "down-regulation of transcription from RNA polymerase II promoter during mitosis", "downregulation of transcription from RNA polymerase II promoter during mitosis", "inhibition of transcription from RNA polymerase II promoter d...
[ "EXACT", "EXACT", "EXACT", "NARROW", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000122", "GO:0044772" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/14896\" xsd:anyURI" ]
null
null
true
true
9
GO:0007072
7,072
obsolete positive regulation of transcription involved in exit from mitosis
biological_process
OBSOLETE. Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
[ "GOC:dph", "GOC:isa_complete", "GOC:tb" ]
This term was obsoleted because it represents a GO-CAM model.
[ "activation of transcription on exit from mitosis" ]
[ "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0045893" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26002\" xsd:anyURI" ]
null
null
true
true
2
GO:0007073
7,073
obsolete positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter
biological_process
OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
[ "GOC:dph", "GOC:tb" ]
This term was obsoleted because it represents a GO-CAM model.
[ "activation of transcription on exit from mitosis, from Pol I promoter", "activation of transcription on exit from mitosis, from RNA polymerase I promoter" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0010458", "GO:0045943" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26002\" xsd:anyURI" ]
null
null
true
true
9
GO:0007074
7,074
obsolete positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter
biological_process
OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
[ "GOC:dph", "GOC:tb" ]
This term was obsoleted because it represents a GO-CAM model.
[ "activation of transcription on exit from mitosis, from Pol II promoter", "activation of transcription on exit from mitosis, from RNA polymerase II promoter" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0010458", "GO:0045944" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26002\" xsd:anyURI" ]
null
null
true
true
4
GO:0007075
7,075
obsolete positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter
biological_process
OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
[ "GOC:dph", "GOC:tb" ]
This term was obsoleted because it represents a GO-CAM model.
[ "activation of transcription on exit from mitosis, from Pol III promoter", "activation of transcription on exit from mitosis, from RNA polymerase III promoter" ]
[ "NARROW", "NARROW" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0010458", "GO:0045945" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26002\" xsd:anyURI" ]
null
null
true
true
5
GO:0007076
7,076
mitotic chromosome condensation
biological_process
The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
[ "GOC:mah", "ISBN:0815316194" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-2299718 \"Condensation of Prophase Chromosomes\"", "Reactome:R-HSA-2514853 \"Condensation of Prometaphase Chromosomes\"" ]
[ "GO:0030261", "GO:1903047" ]
[ "part_of GO:0000070" ]
[ "part_of" ]
[ "GO:0000070" ]
[ "GO:0000070", "GO:0030261", "GO:1903047" ]
[ "GO:0030261", "part_of GO:0000278" ]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0007077
7,077
mitotic nuclear membrane disassembly
biological_process
The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.
[ "GOC:bf", "PMID:32848252" ]
null
[ "local NEB", "mitotic nuclear envelope breakdown", "mitotic nuclear envelope catabolism", "mitotic nuclear envelope degradation", "mitotic nuclear envelope disassembly", "NEB", "nuclear envelope breakdown" ]
[ "BROAD", "EXACT", "RELATED", "RELATED", "RELATED", "BROAD", "BROAD" ]
[]
[]
[ "Reactome:R-HSA-2980766 \"Nuclear Envelope Breakdown\"" ]
[ "GO:0051081", "GO:1903047" ]
[]
[]
[]
[ "GO:0051081", "GO:1903047" ]
[ "GO:0051081", "part_of GO:0000278" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007079
7,079
mitotic chromosome movement towards spindle pole
biological_process
The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
[ "GOC:ai" ]
null
[ "chromosome migration to spindle pole during mitosis", "chromosome movement towards spindle pole during mitosis", "mitotic chromosome movement", "mitotic chromosome movement to spindle pole", "mitotic sister chromosome movement towards spindle pole", "sister chromosome movement towards spindle pole during...
[ "EXACT", "EXACT", "BROAD", "EXACT", "EXACT", "EXACT" ]
[ "GO:0007082" ]
[]
[]
[ "GO:0051305", "GO:1903047" ]
[ "part_of GO:0000070" ]
[ "part_of" ]
[ "GO:0000070" ]
[ "GO:0000070", "GO:0051305", "GO:1903047" ]
[ "GO:0051305", "part_of GO:0000278" ]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0007080
7,080
mitotic metaphase chromosome alignment
biological_process
A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
[ "ISBN:0815316194" ]
null
[]
[]
[]
[]
[]
[ "GO:0051310", "GO:1903047" ]
[ "part_of GO:0000070" ]
[ "part_of" ]
[ "GO:0000070" ]
[ "GO:0000070", "GO:0051310", "GO:1903047" ]
[ "GO:0051310", "part_of GO:0000278" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25547\" xsd:anyURI" ]
null
null
false
true
1
GO:0007083
7,083
obsolete mitotic chromosome decondensation
biological_process
OBSOLETE. The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells.
[ "GOC:ai" ]
This term was obsoleted because it is a spontaneous process.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/22814\" xsd:anyURI" ]
null
null
true
true
4
GO:0007084
7,084
mitotic nuclear membrane reassembly
biological_process
The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge.
[ "PMID:26040712", "PMID:28242692", "PMID:32109380", "PMID:32848252" ]
null
[ "mitotic nuclear envelope reassembly", "nuclear envelope repair", "nuclear envelope resealing" ]
[ "RELATED", "BROAD", "BROAD" ]
[]
[]
[ "Reactome:R-HSA-2995410 \"Nuclear Envelope (NE) Reassembly\"" ]
[ "GO:0031468", "GO:0101024" ]
[]
[]
[]
[ "GO:0031468", "GO:0101024" ]
[ "GO:0031468", "part_of GO:0000278" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19950\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20636\" xsd:anyURI" ]
null
null
false
true
3
GO:0007085
7,085
obsolete nuclear membrane vesicle binding to chromatin
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:ai" ]
This term was made obsolete because it represents a molecular function.
[ "nuclear membrane vesicle binding to chromatin" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0003682" ]
[]
null
null
true
true
7
GO:0007086
7,086
obsolete vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly
biological_process
OBSOLETE. The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly.
[ "GOC:jid", "GOC:mah" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31306\" xsd:anyURI" ]
null
null
true
true
2
GO:0007087
7,087
mitotic nuclear pore complex reassembly
biological_process
The cell cycle process in which nuclear pore complexes reform during mitotic cell division.
[ "GOC:ai" ]
null
[]
[]
[]
[]
[]
[ "GO:0051292", "GO:1903047" ]
[ "part_of GO:0007084" ]
[ "part_of" ]
[ "GO:0007084" ]
[ "GO:0007084", "GO:0051292", "GO:1903047" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0007088
7,088
regulation of mitotic nuclear division
biological_process
Any process that modulates the frequency, rate or extent of mitosis.
[ "GOC:curators" ]
null
[ "regulation of mitosis" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007346", "GO:0010564", "GO:0051783" ]
[ "regulates GO:0140014" ]
[ "regulates" ]
[ "GO:0140014" ]
[ "GO:0007346", "GO:0010564", "GO:0051783", "GO:0140014" ]
[ "GO:0065007", "regulates GO:0140014" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007089
7,089
traversing start control point of mitotic cell cycle
biological_process
A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.
[ "GOC:mtg_cell_cycle" ]
null
[]
[]
[ "GO:0000081" ]
[]
[]
[ "GO:1900087" ]
[]
[]
[]
[ "GO:1900087" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0007090
7,090
obsolete regulation of S phase of mitotic cell cycle
biological_process
OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle.
[ "GOC:curators" ]
This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.
[ "regulation of S phase of mitotic cell cycle", "regulation of S-phase of mitotic cell cycle" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0044772" ]
[]
null
null
true
true
7
GO:0007091
7,091
metaphase/anaphase transition of mitotic cell cycle
biological_process
The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
[ "GOC:mtg_cell_cycle", "PMID:10465783" ]
null
[ "metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process", "mitotic metaphase/anaphase transition" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-68881 \"Mitotic Metaphase/Anaphase Transition\"" ]
[ "GO:0044772", "GO:0044784" ]
[]
[]
[]
[ "GO:0044772", "GO:0044784" ]
[ "GO:0044784", "part_of GO:0000278" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24140\" xsd:anyURI" ]
null
null
false
true
3
GO:0007093
7,093
mitotic cell cycle checkpoint signaling
biological_process
A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
[ "GOC:mtg_cell_cycle" ]
null
[ "mitotic cell cycle checkpoint", "mitotic checkpoint", "signal transduction involved in mitotic cell cycle checkpoint", "signal transduction involved in mitotic cell cycle G1/S checkpoint", "signal transduction involved in mitotic G2/M transition checkpoint" ]
[ "EXACT", "RELATED", "EXACT", "NARROW", "NARROW" ]
[ "GO:0031575", "GO:0071780", "GO:0072413", "GO:0072456", "GO:0072474" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0000075", "GO:0045930", "GO:1903047" ]
[]
[]
[]
[ "GO:0000075", "GO:0045930", "GO:1903047" ]
[ "GO:0000075", "part_of GO:0000278" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20935\" xsd:anyURI" ]
null
null
false
true
4
GO:0007094
7,094
mitotic spindle assembly checkpoint signaling
biological_process
A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results ...
[ "GOC:mtg_cell_cycle", "PMID:12360190" ]
null
[ "Dma1-dependent checkpoint", "Mad2-dependent checkpoint", "mitotic cell cycle spindle assembly checkpoint", "mitotic checkpoint", "mitotic spindle assembly checkpoint", "mitotic spindle assembly checkpoint signalling", "SAC-independent checkpoint", "signal transduction involved in Dma1-dependent check...
[ "NARROW", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT", "NARROW", "NARROW", "EXACT", "EXACT", "NARROW", "NARROW", "NARROW", "RELATED", "RELATED", "NARROW", "NARROW", "RELATED", "RELATED" ]
[ "GO:0044810", "GO:0072480", "GO:1902420" ]
[]
[ "Reactome:R-HSA-69618 \"Mitotic Spindle Checkpoint\"" ]
[ "GO:0045841", "GO:0071173", "GO:0071174" ]
[]
[]
[]
[ "GO:0045841", "GO:0071173", "GO:0071174" ]
[ "GO:0071173", "part_of GO:0000278" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/19810\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20935\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24179\" xsd:anyURI" ]
null
null
false
true
6
GO:0007095
7,095
mitotic G2 DNA damage checkpoint signaling
biological_process
A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
[ "GOC:mtg_cell_cycle", "PMID:16299494" ]
null
[ "down regulation of signal transduction involved in mitotic G2 DNA damage checkpoint", "down regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint", "down-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint", "down-regulation of signal transduct...
[ "NARROW", "NARROW", "NARROW", "NARROW", "RELATED", "EXACT", "NARROW", "EXACT", "EXACT", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]
[ "GO:0031572", "GO:0072425", "GO:0072434", "GO:1902504", "GO:1902505", "GO:1902506" ]
[]
[]
[ "GO:0044773", "GO:0044818" ]
[ "happens_during GO:0000085" ]
[ "happens_during" ]
[ "GO:0000085" ]
[ "GO:0000085", "GO:0044773", "GO:0044818" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20935\" xsd:anyURI" ]
null
null
false
true
3
GO:0007096
7,096
regulation of exit from mitosis
biological_process
Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
[ "GOC:rn" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-176409 \"APC/C:Cdc20 mediated degradation of mitotic proteins\"" ]
[ "GO:1901990" ]
[ "regulates GO:0010458" ]
[ "regulates" ]
[ "GO:0010458" ]
[ "GO:0010458", "GO:1901990" ]
[ "GO:0065007", "regulates GO:0010458" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007097
7,097
nuclear migration
biological_process
The directed movement of the nucleus to a specific location within a cell.
[ "GOC:ai" ]
null
[ "establishment of cell nucleus localization", "establishment of localization of nucleus", "establishment of nucleus localisation", "establishment of nucleus localization", "establishment of position of nucleus", "nuclear movement", "nuclear positioning", "nucleus migration", "nucleus positioning", ...
[ "RELATED", "RELATED", "RELATED", "RELATED", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[ "GO:0040023" ]
[]
[]
[ "GO:0046907", "GO:0051647", "GO:0051656" ]
[]
[]
[]
[ "GO:0046907", "GO:0051647", "GO:0051656" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007098
7,098
centrosome cycle
biological_process
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
[ "ISBN:0815316194" ]
null
[ "centrosome organisation", "centrosome organization", "centrosome organization and biogenesis" ]
[ "EXACT", "EXACT", "RELATED" ]
[ "GO:0051297" ]
[]
[]
[ "GO:0022402", "GO:0031023" ]
[]
[]
[]
[ "GO:0022402", "GO:0031023" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0007099
7,099
centriole replication
biological_process
The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and...
[ "GOC:cilia", "GOC:kmv", "ISBN:0815316194", "PMID:9889124" ]
null
[ "centriole duplication", "ciliary basal body duplication", "microtubule basal body duplication" ]
[ "EXACT", "RELATED", "BROAD" ]
[ "GO:0032054" ]
[]
[]
[ "GO:0022402", "GO:0098534" ]
[ "part_of GO:0051298" ]
[ "part_of" ]
[ "GO:0051298" ]
[ "GO:0022402", "GO:0051298", "GO:0098534" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0007100
7,100
mitotic centrosome separation
biological_process
Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the ...
[ "ISBN:0815316194" ]
null
[]
[]
[]
[]
[]
[ "GO:0051299", "GO:1903047" ]
[ "part_of GO:0140014" ]
[ "part_of" ]
[ "GO:0140014" ]
[ "GO:0051299", "GO:0140014", "GO:1903047" ]
[ "GO:0051299", "part_of GO:0140014" ]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0007101
7,101
obsolete male meiosis centrosome cycle
biological_process
OBSOLETE. Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism.
[ "GOC:mah" ]
false
[ "centrosome cycle involved in male meiotic cell cycle" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
5
GO:0007105
7,105
cytokinesis, division site positioning
biological_process
The process in which a contractile ring is positioned in a specific location. This process is critical for both for both symmetric and asymmetric cell divisions.
[ "PMID:26553932", "PMID:28162898" ]
null
[ "contractile ring localization", "cytokinesis, site selection", "division plane positioning", "site selection involved in cell cycle cytokinesis", "site selection involved in cytokinesis" ]
[ "RELATED", "EXACT", "EXACT", "EXACT", "EXACT" ]
[ "GO:0010687" ]
[]
[]
[ "GO:0032506" ]
[]
[]
[]
[ "GO:0032506" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25071\" xsd:anyURI" ]
null
null
false
true
2
GO:0007106
7,106
obsolete cytokinesis, protein recruitment
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:curators" ]
This term was made obsolete because it was not defined.
[ "cytokinesis, protein recruitment" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
5
GO:0007107
7,107
membrane addition at site of cytokinesis
biological_process
Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.
[ "GOC:clt" ]
null
[ "cytokinesis, membrane recruitment/generation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032506", "GO:0061024" ]
[]
[]
[]
[ "GO:0032506", "GO:0061024" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007108
7,108
obsolete cytokinesis, initiation of separation
biological_process
OBSOLETE. The process involved in starting cell separation.
[ "GOC:clt", "GOC:dph", "GOC:tb" ]
This term was obsoleted because it was vaguely defined and had very likely been used in error. Consider the child terms of cytokinesis related to ring positioning, assembly, ring constriction etc. which would be more appropriate.
[ "cytokinesis, initiation of separation", "initiation of separation involved in cytokinesis" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
null
null
true
true
6
GO:0007110
7,110
meiosis I cytokinesis
biological_process
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.
[ "GOC:mtg_cell_cycle" ]
null
[ "cytokinesis after meiosis I" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0033206", "GO:0061982" ]
[]
[]
[]
[ "GO:0033206", "GO:0061982" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
8
GO:0007111
7,111
meiosis II cytokinesis
biological_process
A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.
[ "GOC:mtg_cell_cycle" ]
null
[ "cytokinesis after meiosis II" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0033206", "GO:0061983" ]
[]
[]
[]
[ "GO:0033206", "GO:0061983" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0007112
7,112
male meiosis cytokinesis
biological_process
A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells.
[ "GOC:ai" ]
null
[ "cytokinesis after male meiosis", "cytokinesis involved in male meiotic cell cycle" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0033206" ]
[ "part_of GO:0007140" ]
[ "part_of" ]
[ "GO:0007140" ]
[ "GO:0007140", "GO:0033206" ]
[ "GO:0000910", "part_of GO:0007140" ]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007113
7,113
endomitotic cell cycle
biological_process
A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
[ "GOC:curators", "GOC:dos", "GOC:expert_vm" ]
Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins.
[ "endomitosis" ]
[ "RELATED" ]
[]
[]
[ "Wikipedia:Mitosis#Endomitosis" ]
[ "GO:0000278" ]
[]
[]
[]
[ "GO:0000278" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0007114
7,114
cell budding
biological_process
A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
[ "ISBN:0198506732" ]
null
[ "budding" ]
[ "BROAD" ]
[]
[ "goslim_candida", "goslim_yeast" ]
[]
[ "GO:0019954", "GO:0022413", "GO:0051301" ]
[]
[]
[]
[ "GO:0019954", "GO:0022413", "GO:0051301" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007115
7,115
obsolete bud site selection/establishment of cell polarity (sensu Saccharomyces)
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:curators" ]
This term was made obsolete because it represents two processes.
[ "bud site selection/establishment of cell polarity (sensu Saccharomyces)" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000282", "GO:0030010" ]
[]
null
null
true
true
1
GO:0007116
7,116
regulation of cell budding
biological_process
Any process that modulates the frequency, rate or extent of the formation and growth of cell buds.
[ "GOC:mah" ]
null
[ "regulation of budding" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0051302", "GO:1903664" ]
[ "regulates GO:0007114" ]
[ "regulates" ]
[ "GO:0007114" ]
[ "GO:0007114", "GO:0051302", "GO:1903664" ]
[ "GO:0065007", "regulates GO:0007114" ]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0007119
7,119
budding cell isotropic bud growth
biological_process
Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.
[ "GOC:curators" ]
null
[ "isotropic bud growth" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0007117" ]
[]
[]
[]
[ "GO:0007117" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0007120
7,120
axial cellular bud site selection
biological_process
The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell.
[ "GOC:clt" ]
null
[ "axial bud site selection", "axial budding" ]
[ "EXACT", "BROAD" ]
[]
[]
[]
[ "GO:0000282", "GO:0007114" ]
[]
[]
[]
[ "GO:0000282", "GO:0007114" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0007121
7,121
bipolar cellular bud site selection
biological_process
The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
[ "GOC:clt" ]
null
[ "bipolar bud site selection", "bipolar budding", "polar budding" ]
[ "EXACT", "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0000282", "GO:0007114" ]
[]
[]
[]
[ "GO:0000282", "GO:0007114" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
7
GO:0007122
7,122
obsolete loss of asymmetric budding
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it is a phenotype rather than a biological process.
[ "loss of asymmetric budding" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006033" ]
[]
null
null
true
true
1
GO:0007123
7,123
obsolete bud scar accumulation
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:jl" ]
This term was made obsolete because it is a phenotype rather than a biological process.
[ "bud scar accumulation" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000282" ]
[]
null
null
true
true
4
GO:0007124
7,124
pseudohyphal growth
biological_process
The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli.
[ "GOC:krc", "PMID:11104818", "PMID:19347739", "PMID:24710476" ]
null
[]
[]
[]
[ "goslim_candida", "goslim_yeast" ]
[]
[ "GO:0016049", "GO:0070783" ]
[]
[]
[]
[ "GO:0016049", "GO:0070783" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0007125
7,125
obsolete invasive growth
biological_process
OBSOLETE. (Was not defined before being made obsolete).
[ "GOC:mcc" ]
This term was made obsolete because it has been split into two new terms.
[ "invasive growth" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0001403", "GO:0044409" ]
[]
null
null
true
true
9
GO:0007127
7,127
meiosis I
biological_process
The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.
[ "GOC:dph", "GOC:jl", "GOC:mtg_cell_cycle", "PMID:9334324" ]
null
[ "meiosis I nuclear division" ]
[ "EXACT" ]
[]
[]
[ "Wikipedia:Meiosis#Meiosis_I" ]
[ "GO:0061982", "GO:0140013" ]
[ "ends_during GO:0007134" ]
[ "ends_during" ]
[ "GO:0007134" ]
[ "GO:0007134", "GO:0061982", "GO:0140013" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
1
GO:0007128
7,128
meiotic prophase I
biological_process
The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
[ "GOC:mtg_cell_cycle" ]
Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phas...
[]
[]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0051324", "GO:0098764" ]
[]
[]
[]
[ "GO:0051324", "GO:0098764" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0007129
7,129
homologous chromosome pairing at meiosis
biological_process
The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is com...
[ "GOC:mtg_cell_cycle", "PMID:22582262", "PMID:23117617", "PMID:31811152" ]
null
[ "chromosomal pairing", "chromosomal synapsis", "synapsis" ]
[ "RELATED", "NARROW", "NARROW" ]
[]
[]
[ "Wikipedia:Synapsis" ]
[ "GO:0070192" ]
[ "part_of GO:0045143" ]
[ "part_of" ]
[ "GO:0045143" ]
[ "GO:0045143", "GO:0070192" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0007130
7,130
synaptonemal complex assembly
biological_process
The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
[ "ISBN:0198506732" ]
null
[ "synaptonemal complex formation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0022607", "GO:0070192", "GO:0070193" ]
[ "part_of GO:0007129" ]
[ "part_of" ]
[ "GO:0007129" ]
[ "GO:0007129", "GO:0022607", "GO:0070192", "GO:0070193" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0007131
7,131
reciprocal meiotic recombination
biological_process
The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segreg...
[ "PMID:2087779" ]
null
[ "female meiotic recombination", "gene conversion with reciprocal crossover" ]
[ "NARROW", "EXACT" ]
[ "GO:0000021", "GO:0007145" ]
[]
[]
[ "GO:0140527", "GO:1903046" ]
[ "part_of GO:0007127" ]
[ "part_of" ]
[ "GO:0007127" ]
[ "GO:0007127", "GO:0140527", "GO:1903046" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4