ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000070731 | ST6GALNAC2 | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | [
"Q9UJ37"
] | 17 | 76565377-76586956 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"SIAT7",
"SIAT7B",
"SIATL1",
"ST6GalNAII",
"STHM"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 3: Choroid plexus - Cilium | Cluster 27: Breast cancer - Unknown function | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 9 | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 1,117 | 6 |
ENSG00000070748 | CHAT | Choline O-acetyltransferase | [
"P28329"
] | 10 | 49609095-49667942 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002313",
"HPA048547",
"CAB079053"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Neurotransmitter biosynthesis"
] | [
"Acyltransferase",
"Transferase"
] | [
"Congenital myasthenic syndrome",
"Disease variant"
] | [] | [] | [] | [] | null | Supported | Supported | 3 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 95: Tuft cells - Chemosensory signaling | Cluster 43: Placenta - Pregnancy hormone signaling | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 6 | Not detected | Not detected | null | Cell type enriched | Detected in some | 14 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,118 | 8 |
ENSG00000070756 | PABPC1 | Poly(A) binding protein cytoplasmic 1 | [
"P11940"
] | 8 | 100685816-100722809 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011536",
"HPA045423",
"HPA067156"
] | [
"PAB1",
"PABP1",
"PABPC2",
"PABPL1"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"mRNA processing",
"mRNA splicing",
"Nonsense-mediated mRNA decay"
] | [
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 189 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 6: Non-specific - Immune response | Cluster 40: Non-specific - Unknown function | Cluster 84: Apical squamous epithelium - Cornification | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,119 | 3 |
ENSG00000070759 | TESK2 | Testis associated actin remodelling kinase 2 | [
"Q96S53"
] | 1 | 45343883-45491163 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027257",
"HPA063869"
] | [] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 14 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 105: Non-specific - Mixed function | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,120 | 6 |
ENSG00000070761 | CFAP20 | Cilia and flagella associated protein 20 | [
"Q9Y6A4"
] | 16 | 58113592-58129381 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018195"
] | [
"C16orf80",
"fSAP23",
"GTL3"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Principal piece"
] | [
"Equatorial segment"
] | [] | [] | Supported | Uncertain | null | 37 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,121 | 6 |
ENSG00000070778 | PTPN21 | Protein tyrosine phosphatase non-receptor type 21 | [
"Q16825"
] | 14 | 88465778-88555007 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB011468",
"HPA073999"
] | [
"PTPD1",
"PTPRL10"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | 39 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,123 | 7 |
ENSG00000070785 | EIF2B3 | Eukaryotic translation initiation factor 2B subunit gamma | [
"Q9NR50"
] | 1 | 44850522-44986722 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024213",
"HPA024218",
"HPA024219"
] | [
"EIF-2B",
"EIF2Bgamma"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Initiation factor"
] | [
"Disease variant",
"Leukodystrophy"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 32 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 26: Oligodendrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,124 | 6 |
ENSG00000070808 | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha | [
"Q9UQM7"
] | 5 | 150219491-150290093 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004330",
"HPA051783",
"HPA051785",
"HPA053973"
] | [
"CAMKA",
"CaMKIIalpha",
"CaMKIINalpha",
"KIAA0968"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Calmodulin-binding",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Plasma membrane",
"Primary cilium tip",
"Primary cilium transition zone",
"Principal piece"
] | [
"Cell Junctions",
"Perinuclear theca",
"Calyx",
"Connecting piece",
"End piece"
] | [] | [] | Uncertain | Supported | null | 85 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 14 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,125 | 9 |
ENSG00000070814 | TCOF1 | Treacle ribosome biogenesis factor 1 | [
"Q13428"
] | 5 | 150357629-150400308 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033199",
"HPA038237",
"HPA038238"
] | [
"TCS",
"treacle"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Nucleoli fibrillar center"
] | [] | [] | [] | Enhanced | Enhanced | null | 34 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 82: Dendritic cells - Antigen presentation | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 1,126 | 5 |
ENSG00000070831 | CDC42 | Cell division cycle 42 | [
"P60953"
] | 1 | 22052627-22101360 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004360",
"HPA069590"
] | [
"CDC42Hs",
"G25K"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Hydrolase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Microtubules"
] | [
"Cytokinetic bridge"
] | [] | [] | Supported | Approved | null | 239 | Yes | No | Cluster 28: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,127 | 8 |
ENSG00000070882 | OSBPL3 | Oxysterol binding protein like 3 | [
"Q9H4L5"
] | 7 | 24796540-24981634 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000691",
"HPA048401"
] | [
"KIAA0704",
"ORP-3",
"ORP3",
"OSBP3"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Supported | Enhanced | null | 48 | null | Yes | Cluster 42: Non-specific - Vesicular transport | Cluster 53: Neurons - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 78: Plasma cells - Antibody production & ER-stress response | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,128 | 4 |
ENSG00000070886 | EPHA8 | EPH receptor A8 | [
"P29322"
] | 1 | 22563489-22603595 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB009660",
"HPA031433"
] | [
"EEK",
"Hek3"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Neurogenesis"
] | [
"Developmental protein",
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | null | Uncertain | null | 19 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 1: Neuronal - Visual perception | Cluster 109: Neurons - Neuronal signaling | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,129 | 5 |
ENSG00000070950 | RAD18 | RAD18 E3 ubiquitin protein ligase | [
"Q9NS91"
] | 3 | 8775402-8963773 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006716",
"HPA006724",
"HPA008752",
"CAB080160",
"CAB080162"
] | [
"RNF73"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"DNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Nuclear speckles"
] | [] | [] | Supported | Supported | Approved | 67 | null | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 34: Non-specific - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 7: Small intestine - Absorption and Digestion | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Prostate Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Prostate Adenocarcinoma"
] | 1,131 | 8 |
ENSG00000070961 | ATP2B1 | ATPase plasma membrane Ca2+ transporting 1 | [
"P20020"
] | 12 | 89588049-89709366 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005605",
"HPA011166",
"HPA012945"
] | [
"PMCA1"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calmodulin-binding",
"Translocase"
] | [
"Disease variant",
"FDA approved drug targets",
"Intellectual disability"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | Supported | 36 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,132 | 1 |
ENSG00000070985 | TRPM5 | Transient receptor potential cation channel subfamily M member 5 | [
"Q9NZQ8"
] | 11 | 2404515-2444514 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"LTRPC5",
"MTR1"
] | [
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor",
"Voltage-gated channel"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | null | Cluster 24: Non-specific - Unknown function | Cluster 95: Tuft cells - Chemosensory signaling | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in some | 12 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,133 | 5 |
ENSG00000071051 | NCK2 | NCK adaptor protein 2 | [
"O43639"
] | 2 | 105744912-105894274 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016116",
"HPA031004"
] | [
"NCKbeta"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Translation regulation"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 189 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 15: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,134 | 5 |
ENSG00000071054 | MAP4K4 | Mitogen-activated protein kinase kinase kinase kinase 4 | [
"O95819"
] | 2 | 101696850-101894690 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008476"
] | [
"FLH21957",
"HGK",
"NIK"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 58 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 11: White matter - Signal transduction | Cluster 72: Neuronal - Signal transduction | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,135 | 2 |
ENSG00000071082 | RPL31 | Ribosomal protein L31 | [
"P62899"
] | 2 | 101002229-101024032 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA072263"
] | [
"L31"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [] | [] | [] | [] | null | Approved | null | 367 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,137 | 8 |
ENSG00000071127 | WDR1 | WD repeat domain 1 | [
"O75083"
] | 4 | 10068089-10116972 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020804",
"HPA036434",
"HPA070293"
] | [
"AIP1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [
"Disease variant"
] | [
"Plasma membrane",
"Cell Junctions",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 34 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 55: Breast - Lactation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,138 | 7 |
ENSG00000071189 | SNX13 | Sorting nexin 13 | [
"Q9Y5W8"
] | 7 | 17790761-17940501 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"KIAA0713",
"RGS-PX1"
] | [
"Predicted membrane proteins"
] | [
"Protein transport",
"Transport"
] | [
"Signal transduction inhibitor"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 31: Non-specific - Transcription | Cluster 67: Non-specific - Unknown function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,139 | 7 |
ENSG00000071203 | MS4A12 | Membrane spanning 4-domains A12 | [
"Q9NXJ0"
] | 11 | 60492778-60507430 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048616",
"HPA057657"
] | [
"FLJ20217",
"Ms4a10"
] | [
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoli",
"Endoplasmic reticulum",
"Golgi apparatus"
] | [] | [] | Approved | Enhanced | null | 5 | null | null | null | null | Cluster 55: Lymphoma - Immune response | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enriched | Detected in some | 23 | Not detected | Not detected | null | Group enriched | Detected in some | 6 | Cell type enriched | Detected in some | 60 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,140 | 2 |
ENSG00000071205 | ARHGAP10 | Rho GTPase activating protein 10 | [
"A1A4S6"
] | 4 | 147732063-148072776 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039589"
] | [
"FLJ20896",
"FLJ41791",
"GRAF2"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear membrane",
"Cytosol"
] | [] | [] | Approved | null | null | 9 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 110: Mural cells - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,141 | 9 |
ENSG00000071242 | RPS6KA2 | Ribosomal protein S6 kinase A2 | [
"Q15349"
] | 6 | 166409364-166906451 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB026243",
"HPA045061",
"HPA054237",
"CAB069428"
] | [
"HU-2",
"RSK3"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 16 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 5 | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,142 | 1 |
ENSG00000071243 | ING3 | Inhibitor of growth family member 3 | [
"Q9NXR8"
] | 7 | 120950763-120977216 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004762",
"HPA067388",
"HPA067575"
] | [
"Eaf4",
"FLJ20089",
"MEAF4",
"p47ING3"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Growth regulation",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 30 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 35: Non-specific - DNA binding | Cluster 39: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,143 | 7 |
ENSG00000071246 | VASH1 | Vasohibin 1 | [
"Q7L8A9"
] | 14 | 76761468-76783015 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000653"
] | [
"KIAA1036"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell cycle",
"Growth arrest"
] | [
"Carboxypeptidase",
"Hydrolase",
"Protease"
] | [] | [
"Centrosome",
"Basal body"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Uncertain | null | 1 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,144 | 2 |
ENSG00000071282 | LMCD1 | LIM and cysteine rich domains 1 | [
"Q9NZU5"
] | 3 | 8501807-8574668 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024059"
] | [] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [
"Cell Junctions",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 2 | No | No | Cluster 9: T-regs - Cell cycle regulation | Cluster 42: Choroid plexus - Mitochondria | Cluster 27: Breast cancer - Unknown function | Cluster 103: Non-specific - Basic cellular processes | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 6 | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | 1,145 | 4 |
ENSG00000071462 | BUD23 | BUD23 rRNA methyltransferase and ribosome maturation factor | [
"O43709"
] | 7 | 73683597-73698212 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052185"
] | [
"MERM1",
"MGC19709",
"MGC2022",
"MGC5140",
"PP3381",
"WBMT",
"WBSCR22"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"rRNA processing",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Methyltransferase",
"Transferase"
] | [
"Williams-Beuren syndrome"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 19 | Yes | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 39: Non-specific - Transcription | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 1,146 | 4 |
ENSG00000071539 | TRIP13 | Thyroid hormone receptor interactor 13 | [
"Q15645"
] | 5 | 892884-919357 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005727",
"HPA053093"
] | [
"16E1BP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Meiosis",
"Oogenesis",
"Spermatogenesis"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm",
"Nuclear speckles"
] | [
"Cytosol",
"Acrosome",
"Equatorial segment",
"Principal piece"
] | [] | [] | Approved | Enhanced | null | 108 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 14: Neurons - Synaptic function | Cluster 29: Non-specific - Unknown function | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 6 | 6 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,148 | 2 |
ENSG00000071553 | ATP6AP1 | ATPase H+ transporting accessory protein 1 | [
"Q15904"
] | X | 154428633-154436516 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB015218"
] | [
"16A",
"Ac45",
"ATP6IP1",
"ATP6S1",
"CF2",
"ORF",
"VATPS1",
"XAP-3",
"XAP3"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Hydrogen ion transport",
"Ion transport",
"Transport"
] | [] | [
"Congenital disorder of glycosylation",
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 49 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 36: Non-specific - mRNA processing | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,149 | 9 |
ENSG00000071564 | TCF3 | Transcription factor 3 | [
"P15923"
] | 19 | 1609291-1652615 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018351",
"HPA049808",
"HPA062476"
] | [
"bHLHb21",
"E2A",
"E47",
"ITF1",
"MGC129647",
"MGC129648",
"p75",
"VDIR"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 48 | No | No | Cluster 17: B-cells - Immunoglobulins | Cluster 7: Non-specific - Ribosome | Cluster 46: Lymphoma - Humoral immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 51: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,150 | 6 |
ENSG00000071575 | TRIB2 | Tribbles pseudokinase 2 | [
"Q92519"
] | 2 | 12716910-12742734 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001305"
] | [
"GS3955",
"TRB2"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [] | [
"Protein kinase inhibitor"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 11 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 2: Neurons - Nucleosome | Cluster 69: Skin cancer - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,151 | 1 |
ENSG00000071626 | DAZAP1 | DAZ associated protein 1 | [
"Q96EP5"
] | 19 | 1407569-1435687 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004201",
"HPA004631"
] | [
"MGC19907"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Developmental protein",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Midbody",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 17 | Yes | null | Cluster 13: Non-specific - Mitochondria | Cluster 6: Non-specific - Immune response | Cluster 23: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 47: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,152 | 5 |
ENSG00000071655 | MBD3 | Methyl-CpG binding domain protein 3 | [
"O95983"
] | 19 | 1573596-1592865 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013265",
"HPA063189"
] | [] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 85 | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 23: Non-specific - Transcription | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 2: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,153 | 2 |
ENSG00000071677 | PRLH | Prolactin releasing hormone | [
"P81277"
] | 2 | 237566574-237567175 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA014976"
] | [
"PRH"
] | [
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [] | [] | [
"Secreted in brain"
] | [
"Hormone"
] | null | Uncertain | null | null | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,154 | 4 |
ENSG00000071794 | HLTF | Helicase like transcription factor | [
"Q14527"
] | 3 | 149030127-149086554 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015284",
"HPA049001"
] | [
"HIP116A",
"HLTF1",
"RNF80",
"SMARCA3",
"SNF2L3"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Ubl conjugation pathway"
] | [
"Activator",
"Chromatin regulator",
"DNA-binding",
"Helicase",
"Hydrolase",
"Multifunctional enzyme",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 24 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 25: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,155 | 6 |
ENSG00000071859 | FAM50A | Family with sequence similarity 50 member A | [
"Q14320"
] | X | 154444141-154450654 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003585"
] | [
"9F",
"DXS9928E",
"HXC-26",
"XAP5"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 28 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 36: Non-specific - mRNA processing | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,156 | 8 |
ENSG00000071894 | CPSF1 | Cleavage and polyadenylation specific factor 1 | [
"Q10570"
] | 8 | 144393229-144409335 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065167",
"HPA068906"
] | [
"CPSF160"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [
"RNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 42 | No | No | Cluster 33: Non-specific - ATP binding | Cluster 37: Neurons - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 65: Non-specific - Cell growth & division | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,158 | 2 |
ENSG00000071909 | MYO3B | Myosin IIIB | [
"Q8WXR4"
] | 2 | 170178145-170655171 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045483"
] | [] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Hearing",
"Sensory transduction",
"Vision"
] | [
"Actin-binding",
"Kinase",
"Motor protein",
"Myosin",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | 3 | null | null | null | null | Cluster 11: Neuronal - Sensory perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,159 | 8 |
ENSG00000071967 | CYBRD1 | Cytochrome b reductase 1 | [
"Q53TN4"
] | 2 | 171522247-171558129 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014757"
] | [
"CYB561A2",
"DCYTB",
"FLJ23462",
"FRRS3"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Electron transport",
"Transport"
] | [
"Oxidoreductase",
"Translocase"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 39: Astrocytes - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 1,160 | 8 |
ENSG00000071991 | CDH19 | Cadherin 19 | [
"Q9H159"
] | 18 | 66501083-66604138 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA056332"
] | [
"CDH7"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 69: Skin cancer - ECM organization | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 35: Non-specific - Mixed function | Group enriched | Detected in many | 4 | Group enriched | Detected in some | 7 | Cancer enriched | Detected in some | 22 | Cell type enriched | Detected in some | 8 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,161 | 7 |
ENSG00000071994 | PDCD2 | Programmed cell death 2 | [
"Q16342"
] | 6 | 170575295-170584692 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026713",
"HPA075534"
] | [
"RP8",
"ZMYND7"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytokinetic bridge"
] | [] | [] | Approved | Approved | null | 21 | Yes | No | Cluster 3: Non-specific - Nuclear processes | Cluster 55: Non-specific - Transcription | Cluster 28: Non-specific - Nuclear processes | Cluster 17: Non-specific - RNA processing | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,162 | 7 |
ENSG00000072041 | SLC6A15 | Solute carrier family 6 member 15 | [
"Q9H2J7"
] | 12 | 84859491-84913629 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008609"
] | [
"FLJ10316",
"hv7-3",
"NTT73",
"SBAT1",
"V7-3"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Ion transport",
"Neurotransmitter transport",
"Sodium transport",
"Symport",
"Transport"
] | [] | [] | [
"Nucleoli"
] | [
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 45 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,163 | 1 |
ENSG00000072042 | RDH11 | Retinol dehydrogenase 11 | [
"Q8TC12"
] | 14 | 67676800-67695793 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB046011"
] | [
"ARSDR1",
"MDT1",
"SDR7C1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [
"Cataract",
"Dwarfism"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Enhanced | null | 41 | null | null | Cluster 41: Basophils - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 38: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,164 | 8 |
ENSG00000072071 | ADGRL1 | Adhesion G protein-coupled receptor L1 | [
"O94910"
] | 19 | 14147743-14206187 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037974"
] | [
"CIRL1",
"KIAA0821",
"LEC2",
"LPHN1"
] | [
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Autism spectrum disorder",
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | Uncertain | null | 3 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,166 | 3 |
ENSG00000072080 | SPP2 | Secreted phosphoprotein 2 | [
"Q13103"
] | 2 | 234050679-234077134 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"SPP24"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | null | null | null | null | null | null | null | Cluster 5: Rhabdoid - Unknown function | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in single | 4,391 | Not detected | Not detected | null | Cancer enriched | Detected in some | 54 | Cell type enriched | Detected in some | 59 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,167 | 7 |
ENSG00000072110 | ACTN1 | Actinin alpha 1 | [
"P12814"
] | 14 | 68874128-68979440 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004303",
"HPA006035"
] | [] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Plasma membrane",
"Actin filaments",
"Focal adhesion sites"
] | [
"Primary cilium",
"Primary cilium transition zone",
"Cytosol"
] | [] | [] | Approved | Approved | null | 97 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,168 | 4 |
ENSG00000072133 | RPS6KA6 | Ribosomal protein S6 kinase A6 | [
"Q9UK32"
] | X | 84058346-84206356 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002852",
"HPA003904"
] | [
"RSK4"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [
"Nucleoli"
] | [] | [] | Supported | Uncertain | null | 8 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,170 | 9 |
ENSG00000072134 | EPN2 | Epsin 2 | [
"O95208"
] | 17 | 19215615-19336715 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049809",
"HPA053360"
] | [
"EHB21",
"KIAA1065"
] | [
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 17 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 42: Non-specific - Unknown function | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 5 | 0 | 5 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,171 | 3 |
ENSG00000072163 | LIMS2 | LIM zinc finger domain containing 2 | [
"Q7Z4I7"
] | 2 | 127638381-127681786 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058340"
] | [
"PINCH-2",
"PINCH2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Limb-girdle muscular dystrophy"
] | [
"Focal adhesion sites"
] | [] | [] | [] | Supported | Enhanced | null | 4 | null | null | Cluster 18: Non-specific - Translation | Cluster 47: Endothelial cells - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,173 | 7 |
ENSG00000072182 | ASIC4 | Acid sensing ion channel subunit family member 4 | [
"Q96FT7"
] | 2 | 219514170-219538772 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036042"
] | [
"ACCN4",
"BNAC4"
] | [
"Predicted membrane proteins"
] | [
"Ion transport",
"Sodium transport",
"Transport"
] | [
"Ion channel",
"Sodium channel"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | null | null | null | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 6 | Group enriched | Detected in some | 7 | Cancer enriched | Detected in single | 58 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,174 | 7 |
ENSG00000072195 | SPEG | Striated muscle enriched protein kinase | [
"Q15772"
] | 2 | 219434843-219493629 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018904"
] | [
"APEG1",
"BPEG",
"KIAA1297",
"MGC12676",
"MYLK6",
"SPEGalpha",
"SPEGbeta"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Differentiation"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 2 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 74: Non-specific - Signal transduction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,175 | 8 |
ENSG00000072201 | LNX1 | Ligand of numb-protein X 1 | [
"Q8TBB1"
] | 4 | 53459301-53701405 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002235",
"HPA071091"
] | [
"LNX",
"MPDZ",
"PDZRN2"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Cell Junctions"
] | [
"Cytosol"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Approved | null | 380 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,176 | 4 |
ENSG00000072210 | ALDH3A2 | Aldehyde dehydrogenase 3 family member A2 | [
"P51648"
] | 17 | 19648136-19685760 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014769",
"CAB020692"
] | [
"ALDH10",
"FALDH",
"SLS"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [
"Disease variant",
"Ichthyosis",
"Intellectual disability"
] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 21 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 36: Choroid plexus - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 26: Keratinocytes - Keratinization | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,177 | 4 |
ENSG00000072274 | TFRC | Transferrin receptor | [
"P02786"
] | 3 | 196012511-196082153 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000153",
"HPA028598"
] | [
"CD71",
"p90",
"TFR1"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Enzymes",
"Essential proteins",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",... | [
"Endocytosis",
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Receptor",
"Transducer"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Endosomes",
"Lysosomes"
] | [] | [
"Secreted to blood"
] | [
"Receptor"
] | Supported | Enhanced | null | 139 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 51: Myeloma - Immunoglobulins | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 5 | 2 | 4 | [
"Lung Squamous Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,178 | 3 |
ENSG00000072310 | SREBF1 | Sterol regulatory element binding transcription factor 1 | [
"P36956"
] | 17 | 17810399-17837002 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043343",
"HPA069227"
] | [
"bHLHd1",
"SREBP-1c",
"SREBP1",
"SREBP1a"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transcription factors"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Steroid metabolism",
"Sterol metabolism",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Disease variant",
"Ichthyosis"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 34 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,179 | 8 |
ENSG00000072315 | TRPC5 | Transient receptor potential cation channel subfamily C member 5 | [
"Q9UL62"
] | X | 111768011-112082776 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"PPP1R159"
] | [
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | null | null | 3 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in single | null | Not detected | Not detected | null | Cancer enriched | Detected in single | 9 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,180 | 5 |
ENSG00000072364 | AFF4 | ALF transcription elongation factor 4 | [
"Q9UHB7"
] | 5 | 132875395-132963634 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023690",
"HPA029634",
"HPA076229"
] | [
"AF5Q31",
"MCEF"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism",
"Obesity",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center",
"Nuclear bodies"
] | [] | [] | Supported | Approved | null | 39 | null | null | Cluster 24: Non-specific - Transcription | Cluster 31: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,181 | 6 |
ENSG00000072401 | UBE2D1 | Ubiquitin conjugating enzyme E2 D1 | [
"P51668"
] | 10 | 58334979-58370751 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003920"
] | [
"E2(17)KB1",
"SFT",
"UBC4/5",
"UBCH5",
"UbcH5A"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 197 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 5 | 0 | 5 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,182 | 6 |
ENSG00000072415 | PALS1 | Protein associated with LIN7 1, MAGUK p55 family member | [
"Q8N3R9"
] | 14 | 67240713-67336061 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000993",
"HPA063890"
] | [
"FLJ12615",
"MPP5"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [
"Cell Junctions",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 47 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,183 | 3 |
ENSG00000072501 | SMC1A | Structural maintenance of chromosomes 1A | [
"Q14683"
] | X | 53374149-53422728 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005499",
"HPA005500",
"CAB025404"
] | [
"DXS423E",
"KIAA0178",
"SB1.8",
"SMC1L1",
"Smcb"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA repair",
"Meiosis",
"Mitosis"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Supported | null | 135 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 25: Non-specific - Transcription | Cluster 36: Non-specific - mRNA processing | Cluster 27: Non-specific - Cell proliferation | Cluster 80: Thymus - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 1,185 | 7 |
ENSG00000072506 | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10 | [
"Q99714"
] | X | 53431258-53434370 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001432"
] | [
"17b-HSD10",
"ABAD",
"CAMR",
"ERAB",
"HADH2",
"MHBD",
"MRPP2",
"MRXS10",
"SDR5C1"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism",
"Steroid metabolism",
"tRNA processing"
] | [
"Oxidoreductase"
] | [
"Disease variant",
"FDA approved drug targets",
"Intellectual disability",
"Neurodegeneration"
] | [] | [] | [] | [] | null | Approved | null | 57 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 45: Non-specific - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,186 | 3 |
ENSG00000072518 | MARK2 | Microtubule affinity regulating kinase 2 | [
"Q7KZI7"
] | 11 | 63838928-63911020 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038790",
"HPA074905"
] | [
"EMK1",
"PAR-1",
"PAR-1B",
"Par1b"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Wnt signaling pathway"
] | [
"Developmental protein",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Approved | null | 71 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,187 | 8 |
ENSG00000072571 | HMMR | Hyaluronan mediated motility receptor | [
"O75330"
] | 5 | 163460203-163491941 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002433",
"HPA040025",
"HPA043926",
"HPA061524"
] | [
"CD168",
"RHAMM"
] | [
"CD markers",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"FDA approved drug targets"
] | [
"Microtubules"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Enhanced | Enhanced | null | 27 | Yes | Yes | Cluster 13: Non-specific - Mitochondria | Cluster 30: White matter - Myelination | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 6 | 8 | 2 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,188 | 8 |
ENSG00000072609 | CHFR | Checkpoint with forkhead and ring finger domains | [
"Q96EP1"
] | 12 | 132822187-132956304 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045768",
"HPA073826"
] | [
"FLJ10796",
"RNF196"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nuclear bodies",
"Microtubules"
] | [] | [] | [] | Uncertain | Approved | null | 29 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 48: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 51: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,189 | 9 |
ENSG00000072657 | TRHDE | Thyrotropin releasing hormone degrading enzyme | [
"Q9UKU6"
] | 12 | 72087266-72670758 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"PAP-II",
"PGPEP2",
"TRH-DE"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Aminopeptidase",
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [] | [] | [] | [] | null | null | null | 7 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 65: Non-specific - Unknown function | Cluster 89: Adipocytes - Lipid metabolism | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,190 | 6 |
ENSG00000072682 | P4HA2 | Prolyl 4-hydroxylase subunit alpha 2 | [
"O15460"
] | 5 | 132190147-132295315 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016997",
"HPA027824",
"CAB062557"
] | [
"C-P4Halpha(II)",
"lncRNA-PE"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Dioxygenase",
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Endoplasmic reticulum",
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Enhanced | Enhanced | null | 18 | No | No | Cluster 35: Neutrophils - Protein binding | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 108: Fibroblasts - ECM organization | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 7 | 0 | 7 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,191 | 4 |
ENSG00000072694 | FCGR2B | Fc gamma receptor IIb | [
"P31994"
] | 1 | 161663143-161678654 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB007796",
"HPA014730"
] | [
"CD32",
"CD32B",
"FCG2",
"FcgammaRIIb",
"FCGR2",
"FcGRIIB"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Host-virus interaction"
] | [
"IgG-binding protein",
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"Proto-oncogene",
"Systemic lupus erythematosus"
] | [] | [] | [] | [] | null | Enhanced | null | 8 | null | null | Cluster 32: Basophils - Transcription | Cluster 8: Immune cells - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in all | 10 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,192 | 3 |
ENSG00000072736 | NFATC3 | Nuclear factor of activated T cells 3 | [
"Q12968"
] | 16 | 68084751-68229259 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050665"
] | [
"NFAT4",
"NFATX"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | null | null | 3 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 25: Non-specific - Transcription | Cluster 68: Non-specific - Cell cycle regulation | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,193 | 9 |
ENSG00000072756 | TRNT1 | TRNA nucleotidyl transferase 1 | [
"Q96Q11"
] | 3 | 3126933-3153435 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036938"
] | [
"CCA1",
"CGI-47",
"MtCCA"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Nucleotidyltransferase",
"RNA-binding",
"Transferase"
] | [
"Disease variant",
"Retinitis pigmentosa"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | null | Yes | No | Cluster 41: Basophils - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 8: Non-specific - Basic cellular processes | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 1,194 | 4 |
ENSG00000072778 | ACADVL | Acyl-CoA dehydrogenase very long chain | [
"P49748"
] | 17 | 7217125-7225266 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019006",
"HPA020595"
] | [
"ACAD6",
"LCACD",
"VLCAD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [
"Cardiomyopathy",
"Disease variant"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | Supported | Enhanced | null | 10 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 42: Non-specific - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,195 | 1 |
ENSG00000072786 | STK10 | Serine/threonine kinase 10 | [
"O94804"
] | 5 | 172042079-172188224 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015083",
"HPA015500",
"CAB020840"
] | [
"LOK",
"PRO2729"
] | [
"Disease related genes",
"Enzymes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | Supported | Enhanced | null | 8 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 25: Non-specific - Transcription | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,196 | 6 |
ENSG00000072803 | FBXW11 | F-box and WD repeat domain containing 11 | [
"Q9UKB1"
] | 5 | 171861549-172006873 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA072204"
] | [
"BTRC2",
"BTRCP2",
"Fbw11",
"Fbw1b",
"FBXW1B",
"Hos",
"KIAA0696"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Cell cycle",
"Host-virus interaction",
"Ubl conjugation pathway",
"Wnt signaling pathway"
] | [] | [
"Disease variant"
] | [
"Vesicles",
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 172 | null | null | Cluster 32: Basophils - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,197 | 8 |
ENSG00000072818 | ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | [
"Q15027"
] | 17 | 7336529-7351477 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA075570"
] | [
"CENTB1",
"KIAA0050"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"GTPase activation"
] | [
"Cancer-related genes"
] | [
"Golgi apparatus"
] | [] | [] | [] | Uncertain | Approved | null | 11 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 6: Non-specific - Immune response | Cluster 59: Leukemia - T-cell receptor | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 58 | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 11 | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,198 | 9 |
ENSG00000072832 | CRMP1 | Collapsin response mediator protein 1 | [
"Q14194"
] | 4 | 5748084-5893086 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035640",
"CAB037313"
] | [
"DPYSL1",
"DRP-1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Centrosome"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 23 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 4 | Group enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Colon Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,199 | 7 |
ENSG00000072840 | EVC | EvC ciliary complex subunit 1 | [
"P57679"
] | 4 | 5711201-5814305 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008703",
"HPA016046"
] | [
"DWF-1",
"EVC1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [] | [
"Ciliopathy",
"Disease variant",
"Dwarfism",
"Ectodermal dysplasia"
] | [
"Nucleoplasm",
"Basal body"
] | [
"Primary cilium",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,200 | 1 |
ENSG00000072849 | DERL2 | Derlin 2 | [
"Q9GZP9"
] | 17 | 5471254-5486811 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB037287",
"HPA048957",
"HPA056551"
] | [
"CGI-101",
"derlin-2",
"F-LAN-1",
"F-LANa",
"FLANa"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Host-virus interaction",
"Unfolded protein response"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Enhanced | null | 62 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 42: Non-specific - Unknown function | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,201 | 3 |
ENSG00000072858 | SIDT1 | SID1 transmembrane family member 1 | [
"Q9NXL6"
] | 3 | 113532555-113629575 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA035862"
] | [
"FLJ20174",
"SID-1"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 55: Lymphoma - Immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 34: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,202 | 6 |
ENSG00000072864 | NDE1 | NudE neurodevelopment protein 1 | [
"Q9NXR1"
] | 16 | 15643267-15734691 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024075"
] | [
"FLJ20101",
"NDE",
"nudE"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Differentiation",
"Mitosis",
"Neurogenesis"
] | [
"Developmental protein"
] | [
"Lissencephaly"
] | [] | [] | [] | [] | null | Approved | null | 16 | null | Yes | Cluster 7: Non-specific - Innate immune response | Cluster 28: Oligodendrocytes - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 102: Non-specific - Mixed function | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,203 | 6 |
ENSG00000072952 | IRAG1 | Inositol 1,4,5-triphosphate receptor associated 1 | [
"Q9Y6F6"
] | 11 | 10573091-10693988 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008704"
] | [
"IRAG",
"JAW1L",
"MRVI1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 74: Non-specific - Signal transduction | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 4 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,204 | 3 |
ENSG00000072958 | AP1M1 | Adaptor related protein complex 1 subunit mu 1 | [
"Q9BXS5"
] | 19 | 16197854-16245906 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045256",
"HPA077258"
] | [
"AP47",
"CLAPM2",
"mu1A"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction",
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 99 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,206 | 3 |
ENSG00000073008 | PVR | PVR cell adhesion molecule | [
"P15151"
] | 19 | 44643798-44666162 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012568",
"HPA064739"
] | [
"CD155",
"HVED",
"Necl-5",
"NECL5",
"PVS",
"Tage4"
] | [
"CD markers",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion",
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [] | [
"Nucleoplasm",
"Vesicles",
"Plasma membrane"
] | [] | [
"Secreted - unknown location"
] | [
"Receptor"
] | Supported | Approved | null | 58 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 15: Kidney cancer - Membrane components | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | 1,207 | 3 |
ENSG00000073050 | XRCC1 | X-ray repair cross complementing 1 | [
"P18887"
] | 19 | 43543311-43580473 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005427",
"HPA006717"
] | [
"RCC"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [] | [
"Cancer-related genes",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 63 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,208 | 7 |
ENSG00000073060 | SCARB1 | Scavenger receptor class B member 1 | [
"Q8WTV0"
] | 12 | 124776856-124882668 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066285",
"CAB070124",
"HPA072449"
] | [
"CD36L1",
"CLA-1",
"CLA1",
"SR-BI",
"SRB1"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [] | [
"Vesicles"
] | [
"Lysosomes",
"Rods & Rings"
] | [] | [] | Approved | Enhanced | null | 13 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 7: Liver cancer - Metabolism | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 10 | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,209 | 2 |
ENSG00000073067 | CYP2W1 | Cytochrome P450 family 2 subfamily W member 1 | [
"Q8TAV3"
] | 7 | 983181-989640 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FLJ20359",
"MGC34287"
] | [
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | null | null | 6 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 37: Skin - Keratinization | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,210 | 9 |
ENSG00000073146 | MOV10L1 | Mov10 like RISC complex RNA helicase 1 | [
"Q9BXT6"
] | 22 | 50089879-50161690 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019034"
] | [
"CHAMP",
"DJ402G11.8",
"DKFZp434B0717"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein",
"Helicase",
"Hydrolase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 10: Ciliated cells - Ion channel activity | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in many | 12 | Low cancer specificity | Detected in single | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,212 | 7 |
ENSG00000073150 | PANX2 | Pannexin 2 | [
"Q96RD6"
] | 22 | 50170731-50180295 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA004624",
"HPA039117"
] | [
"hPANX2",
"PX2"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 24: Neurons - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,213 | 7 |
ENSG00000073169 | SELENOO | Selenoprotein O | [
"Q9BVL4"
] | 22 | 50201011-50217616 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071795",
"HPA079100"
] | [
"SELO"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Nucleotidyltransferase",
"Transferase"
] | [] | [
"Mitochondria"
] | [
"Mitotic chromosome"
] | [] | [] | Supported | Approved | null | 8 | Yes | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 2: Neurons - Nucleosome | Cluster 66: Non-specific - Mitochondria | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,214 | 1 |
ENSG00000073350 | LLGL2 | LLGL scribble cell polarity complex component 2 | [
"Q6P1M3"
] | 17 | 75525080-75575209 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022913"
] | [
"HGL",
"Hugl-2"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Exocytosis"
] | [] | [] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Supported | Uncertain | null | 18 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 26: Oligodendrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 65: Non-specific - Cell growth & division | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 1,217 | 4 |
ENSG00000073417 | PDE8A | Phosphodiesterase 8A | [
"O60658"
] | 15 | 84980440-85139145 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007722"
] | [
"HsT19550"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 7: Liver cancer - Metabolism | Cluster 80: Oligodendrocytes - Myelination | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,218 | 3 |
ENSG00000073464 | CLCN4 | Chloride voltage-gated channel 4 | [
"P51793"
] | X | 10156975-10237660 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031313",
"HPA063637"
] | [
"ClC-4",
"CLC4"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Ion transport",
"Transport"
] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | Approved | 7 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,219 | 8 |
ENSG00000073536 | NLE1 | Notchless homolog 1 | [
"Q9NVX2"
] | 17 | 35128730-35142304 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018807"
] | [
"FLJ10458",
"NLE"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Notch signaling pathway"
] | [] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 34: Non-specific - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,220 | 9 |
ENSG00000073578 | SDHA | Succinate dehydrogenase complex flavoprotein subunit A | [
"P31040"
] | 5 | 218303-257082 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034929",
"HPA041981"
] | [
"FP",
"SDH2",
"SDHF"
] | [
"Cancer-related genes",
"Citric acid cycle related proteins",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Electron transport",
"Transport",
"Tricarboxylic acid cycle"
] | [
"Oxidoreductase"
] | [
"Cancer-related genes",
"Cardiomyopathy",
"Disease variant",
"FDA approved drug targets",
"Leigh syndrome",
"Neurodegeneration",
"Primary mitochondrial disease",
"Tumor suppressor"
] | [
"Mitochondria"
] | [
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 52 | No | No | Cluster 9: T-regs - Cell cycle regulation | Cluster 45: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 102: Non-specific - Mixed function | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,221 | 5 |
ENSG00000073584 | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | [
"Q969G3"
] | 17 | 40624962-40648654 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003916",
"CAB037318"
] | [
"BAF57"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Neurogenesis"
] | [
"Chromatin regulator",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 166 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 27: Breast cancer - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,222 | 3 |
ENSG00000073598 | FNDC8 | Fibronectin type III domain containing 8 | [
"Q8TC99"
] | 17 | 35121615-35130732 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026521",
"HPA059803"
] | [
"DKFZp434H2215"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 7 | null | null | null | null | Cluster 46: Lymphoma - Humoral immune response | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in single | 500 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,223 | 5 |
ENSG00000073605 | GSDMB | Gasdermin B | [
"Q8TAX9"
] | 17 | 39904595-39919854 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013681",
"HPA023925",
"HPA052407"
] | [
"GSDML",
"PRO2521"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Cytolysis",
"Necrosis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 11: T-cells - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,224 | 8 |
ENSG00000073614 | KDM5A | Lysine demethylase 5A | [
"P29375"
] | 12 | 280057-389320 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006201"
] | [
"JARID1A",
"RBBP2"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"Developmental protein",
"Dioxygenase",
"Oxidoreductase"
] | [
"Autism",
"Autism spectrum disorder",
"Cancer-related genes",
"Intellectual disability"
] | [
"Nuclear bodies"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 22 | null | null | Cluster 41: Basophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 38: Non-specific - Transcription | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,225 | 8 |
ENSG00000073670 | ADAM11 | ADAM metallopeptidase domain 11 | [
"O75078"
] | 17 | 44758988-44781846 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA074550"
] | [
"MDC"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 11: Neuronal - Sensory perception | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 9 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,226 | 6 |
ENSG00000073711 | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha | [
"Q06190"
] | 3 | 135965728-136147894 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035829",
"HPA035830",
"HPA065338"
] | [
"PPP2R3",
"PR130",
"PR72"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Flagellar centriole",
"Mid piece"
] | [] | [] | Approved | Uncertain | null | 9 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 62: Skeletal muscle - Muscle contraction | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,227 | 2 |
ENSG00000073712 | FERMT2 | FERM domain containing kindlin 2 | [
"Q96AC1"
] | 14 | 52857268-52952435 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040505",
"HPA072965"
] | [
"KIND2",
"mig-2",
"PLEKHC1",
"UNC112B"
] | [
"Predicted intracellular proteins"
] | [
"Cell adhesion",
"Cell shape",
"Wnt signaling pathway"
] | [] | [] | [
"Focal adhesion sites"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 19 | null | null | Cluster 1: T-cells - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,228 | 8 |
ENSG00000073734 | ABCB11 | ATP binding cassette subfamily B member 11 | [
"O95342"
] | 2 | 168915498-169031324 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019035"
] | [
"ABC16",
"BSEP",
"PFIC-2",
"PFIC2",
"PGY4",
"SPGP"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [
"Disease variant",
"Intrahepatic cholestasis"
] | [
"Nucleoplasm",
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Uncertain | Enhanced | null | 1 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 13 | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in single | 112 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,229 | 2 |
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