ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000076554 | TPD52 | Tumor protein D52 | [
"P55327"
] | 8 | 80034745-80231232 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028427",
"HPA062167"
] | [
"D52",
"hD52",
"N8L"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Golgi apparatus",
"Primary cilium"
] | [] | [] | Approved | Enhanced | null | 18 | null | null | Cluster 24: Non-specific - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 60: Prostate cancer - Unknown function | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 42: Retina - Visual perception | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,338 | 5 |
ENSG00000076555 | ACACB | Acetyl-CoA carboxylase beta | [
"O00763"
] | 12 | 109116587-109268226 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006554"
] | [
"ACACbeta",
"ACC-beta",
"ACC2",
"ACCB",
"ACCbeta",
"HACC275"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Allosteric enzyme",
"Ligase",
"Multifunctional enzyme"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Enhanced | null | 6 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 19: Astrocytes - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 89: Adipocytes - Lipid metabolism | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 1,339 | 9 |
ENSG00000076604 | TRAF4 | TNF receptor associated factor 4 | [
"Q9BUZ4"
] | 17 | 28744011-28750956 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009055",
"HPA021904",
"HPA052377"
] | [
"CART1",
"MLN62",
"RNF83"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Apoptosis",
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [
"Developmental protein",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 119 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 11: White matter - Signal transduction | Cluster 55: Lymphoma - Immune response | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 5 | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 1,340 | 7 |
ENSG00000076641 | PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | [
"Q9NWQ8"
] | 8 | 80967810-81112068 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001632",
"HPA066527"
] | [
"CBP",
"PAG"
] | [
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [] | [] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 15 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 25: Non-specific - Transcription | Cluster 46: Lymphoma - Humoral immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,341 | 1 |
ENSG00000076662 | ICAM3 | Intercellular adhesion molecule 3 | [
"P32942"
] | 19 | 10333776-10339661 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002498",
"HPA049820"
] | [
"CD50",
"CDW50",
"ICAM-R"
] | [
"CD markers",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Phagocytosis"
] | [] | [] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Nuclear membrane"
] | [] | [] | Approved | Enhanced | null | 10 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 1,343 | 5 |
ENSG00000076685 | NT5C2 | 5'-nucleotidase, cytosolic II | [
"P49902"
] | 10 | 103087185-103277605 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003751"
] | [
"cN-II",
"GMP",
"NT5B",
"PNT5",
"SPG45",
"SPG65"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Nucleotide metabolism"
] | [
"Allosteric enzyme",
"Hydrolase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [] | [] | [] | [] | null | Approved | null | 20 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,344 | 6 |
ENSG00000076706 | MCAM | Melanoma cell adhesion molecule | [
"P43121"
] | 11 | 119308529-119321521 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002147",
"HPA008848"
] | [
"CD146",
"HEMCAM",
"MelCAM",
"METCAM",
"MUC18"
] | [
"CD markers",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 28 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 69: Skin cancer - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Group enriched | Detected in all | 4 | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,345 | 9 |
ENSG00000076716 | GPC4 | Glypican 4 | [
"O75487"
] | X | 133300103-133415489 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030834",
"HPA030836"
] | [
"K-glypican"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Deafness",
"Disease variant",
"Intellectual disability"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Approved | Approved | null | 23 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Cancer enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,346 | 1 |
ENSG00000076770 | MBNL3 | Muscleblind like splicing regulator 3 | [
"Q9NUK0"
] | X | 132369320-132489968 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001584",
"HPA001793"
] | [
"CHCR",
"FLJ11316",
"MBLX39",
"MBXL"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Developmental protein"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 32: Basophils - Transcription | Cluster 21: Non-specific - Metabolism | Cluster 18: Liver cancer - Metabolism | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Chromophobe",
"Uterine Corpus Endometrial Carcinoma"
] | 1,347 | 4 |
ENSG00000076826 | CAMSAP3 | Calmodulin regulated spectrin associated protein family member 3 | [
"Q9P1Y5"
] | 19 | 7595863-7618304 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043830"
] | [
"KIAA1543",
"Nezha",
"PPP1R80"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 31 | null | null | null | Cluster 32: Cerebral cortex - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,348 | 5 |
ENSG00000076864 | RAP1GAP | RAP1 GTPase activating protein | [
"P47736"
] | 1 | 21596221-21669357 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001922",
"CAB003851"
] | [
"KIAA0474",
"RAP1GA1",
"RAP1GAP1",
"RAP1GAPII"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | Supported | 7 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | 1,349 | 7 |
ENSG00000076928 | ARHGEF1 | Rho guanine nucleotide exchange factor 1 | [
"Q92888"
] | 19 | 41883173-41930150 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009502",
"HPA012924",
"HPA060784"
] | [
"LBCL2",
"P115-RHOGEF",
"SUB1.5"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation",
"Guanine-nucleotide releasing factor"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 13 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 11: White matter - Signal transduction | Cluster 46: Lymphoma - Humoral immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,351 | 2 |
ENSG00000076944 | STXBP2 | Syntaxin binding protein 2 | [
"Q15833"
] | 19 | 7636772-7647873 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015564",
"HPA063868"
] | [
"Hunc18b",
"MUNC18-2",
"Unc18-2",
"UNC18B"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Exocytosis",
"Protein transport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Approved | null | 7 | No | No | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,352 | 2 |
ENSG00000076984 | MAP2K7 | Mitogen-activated protein kinase kinase 7 | [
"O14733"
] | 19 | 7903843-7914478 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001633",
"CAB004262",
"HPA064711"
] | [
"Jnkk2",
"MKK7",
"PRKMK7"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Stress response"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Uncertain | Supported | null | 27 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 23: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 1,353 | 3 |
ENSG00000077009 | NMRK2 | Nicotinamide riboside kinase 2 | [
"Q9NPI5"
] | 19 | 3933069-3942416 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049909",
"HPA054792",
"HPA072450"
] | [
"ITGB1BP3",
"MIBP",
"NRK2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Pyridine nucleotide biosynthesis"
] | [
"Kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Enhanced | Approved | null | 2 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 34: Testis cancer - Unknown function | Cluster 55: Myocytes - Oxidative muscle function | Cluster 41: Striated muscle - Muscle contraction | Group enriched | Detected in some | 88 | Group enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 10 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,354 | 1 |
ENSG00000077044 | DGKD | Diacylglycerol kinase delta | [
"Q16760"
] | 2 | 233354494-233472104 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027530",
"HPA049101"
] | [
"DGKdelta",
"KIAA0145"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Lipid metabolism",
"Protein transport",
"Transport"
] | [
"Kinase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 6 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 6: Leukemia - Signal transduction | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 24: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,355 | 6 |
ENSG00000077063 | CTTNBP2 | Cortactin binding protein 2 | [
"Q8WZ74"
] | 7 | 117710651-117874139 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009151",
"HPA044654"
] | [
"C7orf8",
"CORTBP2",
"KIAA1758",
"Orf4"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Midbody ring"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 32 | Yes | No | null | Cluster 11: White matter - Signal transduction | Cluster 49: HMC-1 - Innate immune response | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 9 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,356 | 6 |
ENSG00000077080 | ACTL6B | Actin like 6B | [
"O94805"
] | 7 | 100643097-100656448 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045126"
] | [
"ACTL6",
"BAF53B",
"SMARCN2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoli rim"
] | [
"Mitotic chromosome"
] | [] | [] | Approved | Uncertain | null | 28 | Yes | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 7 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,357 | 1 |
ENSG00000077092 | RARB | Retinoic acid receptor beta | [
"P10826"
] | 3 | 24687887-25597932 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002617",
"HPA004174"
] | [
"HAP",
"NR1B2",
"RAR-beta",
"RARbeta",
"RRB2"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Nuclear receptors",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Receptor"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Microphthalmia",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 9 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 105: Non-specific - Mixed function | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,358 | 3 |
ENSG00000077097 | TOP2B | DNA topoisomerase II beta | [
"Q02880"
] | 3 | 25597978-25664909 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004601",
"HPA024120",
"HPA050441"
] | [
"top2beta",
"TOPIIB"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"Isomerase",
"Topoisomerase"
] | [
"Autism spectrum disorder",
"Disease variant",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 42 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 6: Leukemia - Signal transduction | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,359 | 3 |
ENSG00000077147 | TM9SF3 | Transmembrane 9 superfamily member 3 | [
"Q9HD45"
] | 10 | 96518110-96587452 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039609"
] | [
"SMBP"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | 33 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 55: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 17: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,360 | 6 |
ENSG00000077150 | NFKB2 | Nuclear factor kappa B subunit 2 | [
"Q00653"
] | 10 | 102394110-102402524 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008422",
"CAB022098",
"HPA023900"
] | [
"LYT-10",
"NF-kB2",
"p105",
"p49/p100",
"p52"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Proto-oncogene"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 43 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 12: Non-specific - Vasculature | Cluster 55: Lymphoma - Immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 1,361 | 3 |
ENSG00000077152 | UBE2T | Ubiquitin conjugating enzyme E2 T | [
"Q9NPD8"
] | 1 | 202331544-202341984 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002831"
] | [
"FANCT",
"HSPC150"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant",
"Fanconi anemia"
] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Approved | null | null | 13 | null | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 45: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 2 | 4 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,362 | 1 |
ENSG00000077157 | PPP1R12B | Protein phosphatase 1 regulatory subunit 12B | [
"O60237"
] | 1 | 202348699-202592706 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024171",
"HPA024640"
] | [
"MGC131980",
"MGC87886",
"MYPT2",
"PP1bp55"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Actin filaments"
] | [] | [] | [] | Approved | Enhanced | null | 7 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 30: White matter - Myelination | Cluster 5: Rhabdoid - Unknown function | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 7 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 1,363 | 9 |
ENSG00000077232 | DNAJC10 | DnaJ heat shock protein family (Hsp40) member C10 | [
"Q8IXB1"
] | 2 | 182716255-182794464 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031111"
] | [
"ERdj5",
"PDIA19"
] | [
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Approved | null | 21 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 39: Astrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | 1,364 | 2 |
ENSG00000077235 | GTF3C1 | General transcription factor IIIC subunit 1 | [
"Q12789"
] | 16 | 27459555-27549913 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051617",
"HPA075900"
] | [
"TFIIIC220"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Approved | Approved | null | 34 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 23: Choroid plexus - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 1,365 | 2 |
ENSG00000077238 | IL4R | Interleukin 4 receptor | [
"P24394"
] | 16 | 27313668-27364778 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004451",
"HPA050124",
"HPA070380"
] | [
"CD124"
] | [
"Cancer-related genes",
"CD markers",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Immunity"
] | [
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Centriolar satellite"
] | [
"Secreted to blood"
] | [
"Receptor"
] | Supported | Enhanced | null | 12 | null | null | Cluster 34: B-cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,366 | 3 |
ENSG00000077254 | USP33 | Ubiquitin specific peptidase 33 | [
"Q8TEY7"
] | 1 | 77695987-77759852 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005719"
] | [
"KIAA1097",
"VDU1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | [] | Supported | Uncertain | null | 19 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 34: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 89: Adipocytes - Lipid metabolism | Cluster 27: Cerebellum - Synaptic function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,367 | 4 |
ENSG00000077264 | PAK3 | P21 (RAC1) activated kinase 3 | [
"O75914"
] | X | 110944285-111227361 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044791",
"HPA060219"
] | [
"bPAK",
"hPAK3",
"MRX30",
"MRX47"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Allosteric enzyme",
"Developmental protein",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 5 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 1,368 | 2 |
ENSG00000077274 | CAPN6 | Calpain 6 | [
"Q9Y6Q1"
] | X | 111245099-111270483 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040259"
] | [
"CalpM",
"CANPX",
"CAPNX"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Vesicles",
"Centriolar satellite"
] | [] | [] | [] | Uncertain | null | null | 1 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 50: Epididymis - Male reproductive secretion | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,369 | 9 |
ENSG00000077279 | DCX | Doublecortin | [
"O43602"
] | X | 111293779-111412429 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036121",
"HPA059243"
] | [
"DBCN",
"DC",
"LISX",
"SCLH",
"XLIS"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [
"Disease variant",
"Epilepsy",
"Lissencephaly"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | Supported | 21 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 10 | Cancer enriched | Detected in some | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 1,370 | 9 |
ENSG00000077312 | SNRPA | Small nuclear ribonucleoprotein polypeptide A | [
"P09012"
] | 19 | 40750637-40765389 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004652",
"HPA046440",
"HPA054834"
] | [
"Mud1",
"U1-A",
"U1A"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 456 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 46: Brainstem - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,371 | 2 |
ENSG00000077327 | SPAG6 | Sperm associated antigen 6 | [
"O75602"
] | 10 | 22345445-22454224 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA038440"
] | [
"CFAP194",
"CT141",
"FAP194",
"PF16",
"Repro-SA-1"
] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [] | [
"Calyx",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 3: Choroid plexus - Cilium | Cluster 65: Non-specific - Unknown function | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,372 | 9 |
ENSG00000077348 | EXOSC5 | Exosome component 5 | [
"Q9NQT4"
] | 19 | 41386371-41397362 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053150",
"HPA055677"
] | [
"hRrp46p",
"MGC12901",
"p12B",
"RRP41B",
"RRP46",
"Rrp46p"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [
"DNA-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Approved | null | 107 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,373 | 5 |
ENSG00000077380 | DYNC1I2 | Dynein cytoplasmic 1 intermediate chain 2 | [
"Q13409"
] | 2 | 171687409-171750158 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033836",
"HPA040619",
"HPA053987"
] | [
"DIC74",
"DNCI2"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transport"
] | [
"Motor protein"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Microtubules",
"Centrosome",
"Cytosol",
"Flagellar centriole",
"Mid piece",
"Principal piece"
] | [
"End piece"
] | [] | [] | Approved | Supported | null | 77 | null | null | Cluster 32: Basophils - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,374 | 8 |
ENSG00000077420 | APBB1IP | Amyloid beta precursor protein binding family B member 1 interacting protein | [
"Q7Z5R6"
] | 10 | 26438341-26567803 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017009",
"HPA063903"
] | [
"INAG1",
"RIAM"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 4 | No | null | Cluster 35: Neutrophils - Protein binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,375 | 4 |
ENSG00000077454 | LRCH4 | Leucine rich repeats and calponin homology domain containing 4 | [
"O75427"
] | 7 | 100574011-100586129 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037667",
"HPA037668"
] | [
"LRN",
"LRRN1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Focal adhesion sites",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 23 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 39: Non-specific - Transcription | Cluster 102: Non-specific - Mixed function | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,376 | 9 |
ENSG00000077458 | FAM76B | Family with sequence similarity 76 member B | [
"Q5HYJ3"
] | 11 | 95768953-95790409 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036608"
] | [
"MGC33371"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Approved | Approved | null | 10 | No | No | Cluster 33: Non-specific - ATP binding | Cluster 55: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 4 | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,377 | 9 |
ENSG00000077463 | SIRT6 | Sirtuin 6 | [
"Q8N6T7"
] | 19 | 4174109-4182566 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049729",
"HPA071776"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Acyltransferase",
"Chromatin regulator",
"Developmental protein",
"DNA-binding",
"Glycosyltransferase",
"Nucleotidyltransferase",
"RNA-binding",
"Transferase"
] | [
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Supported | null | 98 | No | No | Cluster 29: Non-specific - Unknown function | Cluster 18: Non-specific - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,378 | 3 |
ENSG00000077514 | POLD3 | DNA polymerase delta 3, accessory subunit | [
"Q15054"
] | 11 | 74493851-74669117 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058846"
] | [
"KIAA0039",
"P66",
"P68",
"PPP1R128"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA excision",
"DNA repair",
"DNA replication"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 35 | null | Yes | Cluster 7: Non-specific - Innate immune response | Cluster 31: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,380 | 8 |
ENSG00000077522 | ACTN2 | Actinin alpha 2 | [
"P35609"
] | 1 | 236664141-236764631 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006035",
"HPA008315"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Actin-binding"
] | [
"Cardiomyopathy",
"Disease variant"
] | [
"Actin filaments",
"Focal adhesion sites"
] | [
"Primary cilium",
"Primary cilium transition zone",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 105 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 55: Myocytes - Oxidative muscle function | Cluster 62: Skeletal muscle - Muscle contraction | Group enriched | Detected in many | 35 | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 10 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,381 | 9 |
ENSG00000077549 | CAPZB | Capping actin protein of muscle Z-line subunit beta | [
"P47756"
] | 1 | 19338775-19485539 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031531"
] | [] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin capping",
"Actin-binding"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 905 | No | No | Cluster 25: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 4 | 0 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,382 | 8 |
ENSG00000077585 | GPR137B | G protein-coupled receptor 137B | [
"O60478"
] | 1 | 236142505-236221865 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026422"
] | [
"TM7SF1"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Autophagy"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 82: Dendritic cells - Antigen presentation | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,383 | 4 |
ENSG00000077616 | NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 | [
"Q9Y3Q0"
] | 11 | 90131515-90192894 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA060820",
"HPA065419"
] | [
"GCPIII",
"NAALADASE2"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Carboxypeptidase",
"Dipeptidase",
"Hydrolase",
"Metalloprotease",
"Multifunctional enzyme",
"Protease"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 4 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 34: Testis cancer - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,384 | 6 |
ENSG00000077684 | JADE1 | Jade family PHD finger 1 | [
"Q6IE81"
] | 4 | 128809700-128875224 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020016",
"HPA072897"
] | [
"JADE-1",
"PHF17"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Supported | Approved | null | 19 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 51: Myeloma - Immunoglobulins | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 8: Pancreas - Proteolysis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,385 | 2 |
ENSG00000077713 | SLC25A43 | Solute carrier family 25 member 43 | [
"Q8WUT9"
] | X | 119399336-119454478 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA035188",
"HPA078530"
] | [] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 36: Non-specific - mRNA processing | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | 1,386 | 9 |
ENSG00000077721 | UBE2A | Ubiquitin conjugating enzyme E2 A | [
"P49459"
] | X | 119474802-119591083 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003875",
"HPA051765",
"HPA065898"
] | [
"HHR6A",
"HR6A",
"RAD6A",
"UBC2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Chromatin regulator",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm",
"Plasma membrane",
"Cytosol"
] | [
"Vesicles",
"Flagellar centriole",
"Mid piece",
"Principal piece"
] | [] | [] | Approved | null | null | 51 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 27: Non-specific - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,387 | 8 |
ENSG00000077782 | FGFR1 | Fibroblast growth factor receptor 1 | [
"P11362"
] | 8 | 38400215-38468834 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA009029",
"CAB033614",
"HPA056402"
] | [
"BFGFR",
"CD331",
"CEK",
"FLG",
"FLT2",
"H2",
"H3",
"H4",
"H5",
"KAL2",
"N-SAM"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"RAS pathway related proteins",
"Transporters"
] | [
"Transcription",
"Transcription regulation"
] | [
"Heparin-binding",
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes",
"Craniosynostosis",
"Disease variant",
"Dwarfism",
"FDA approved drug targets",
"Holoprosencephaly",
"Hypogonadotropic hypogonadism",
"Intellectual disability",
"Kallmann syndrome"
] | [
"Microtubules",
"Cytokinetic bridge",
"Mitotic spindle"
] | [
"Primary cilium",
"Centriolar satellite",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Approved | null | 93 | Yes | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 44: Non-specific - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 103: Non-specific - Basic cellular processes | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,388 | 5 |
ENSG00000077800 | FKBP6 | FKBP prolyl isomerase family member 6 (inactive) | [
"O75344"
] | 7 | 73328161-73358637 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041414",
"HPA061109"
] | [
"FKBP36",
"PPIase"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Meiosis",
"RNA-mediated gene silencing",
"Spermatogenesis"
] | [] | [
"Disease variant",
"Williams-Beuren syndrome"
] | [
"Nucleoli fibrillar center",
"Cytosol"
] | [
"Microtubules",
"Cytokinetic bridge"
] | [] | [] | Supported | Enhanced | null | 51 | Yes | null | null | null | Cluster 10: Ciliated cells - Ion channel activity | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in single | 152 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in single | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,389 | 2 |
ENSG00000077935 | SMC1B | Structural maintenance of chromosomes 1B | [
"Q8NDV3"
] | 22 | 45344063-45413619 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA001500"
] | [
"bK268H5",
"SMC1L2"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Meiosis"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 2 | null | null | null | null | Cluster 71: Lymphoma - Inflammatory response | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 97 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in some | 6 | Group enriched | Detected in many | 8 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,390 | 4 |
ENSG00000077943 | ITGA8 | Integrin subunit alpha 8 | [
"P53708"
] | 10 | 15513954-15719922 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003432"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein",
"Integrin",
"Receptor"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 2 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enriched | Detected in many | 10 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,392 | 1 |
ENSG00000077984 | CST7 | Cystatin F | [
"O76096"
] | 20 | 24949269-24959928 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040442"
] | [] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Thiol protease inhibitor"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme inhibitor"
] | null | Enhanced | null | 3 | null | null | Cluster 1: T-cells - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in many | 7 | Cancer enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in all | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Glioblastoma Multiforme"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 1,393 | 4 |
ENSG00000078018 | MAP2 | Microtubule associated protein 2 | [
"P11137"
] | 2 | 209424047-209734147 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001984",
"HPA008273",
"HPA012828"
] | [
"MAP2A",
"MAP2B",
"MAP2C"
] | [
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [
"Plasma membrane",
"Primary cilium",
"Primary cilium tip"
] | [] | [] | Approved | Enhanced | Supported | 10 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 14: Neurons - Synaptic function | Cluster 7: Liver cancer - Metabolism | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in many | 11 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 1,394 | 2 |
ENSG00000078043 | PIAS2 | Protein inhibitor of activated STAT 2 | [
"O75928"
] | 18 | 46803218-46920160 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA068792",
"HPA077584"
] | [
"ARIP3",
"miz",
"PIASX-ALPHA",
"PIASX-BETA",
"ZMIZ4"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"DNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 55 | Yes | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 2: Neurons - Nucleosome | Cluster 13: Non-specific - Mixed function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 67: Testis - Mixed function | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,395 | 6 |
ENSG00000078070 | MCCC1 | Methylcrotonyl-CoA carboxylase subunit 1 | [
"Q96RQ3"
] | 3 | 183015218-183116075 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008310",
"HPA071630"
] | [
"MCCA",
"MCCCalpha"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Ligase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Approved | null | 34 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 81: Alveolar cells - Lung function | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,398 | 6 |
ENSG00000078114 | NEBL | Nebulette | [
"O76041"
] | 10 | 20779973-21293011 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA013994",
"HPA013995"
] | [
"bA165O3.1",
"C10orf113",
"LASP2",
"LNEBL"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | 33 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Tissue enriched | Detected in many | 15 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,401 | 7 |
ENSG00000078124 | ACER3 | Alkaline ceramidase 3 | [
"Q9NUN7"
] | 11 | 76860859-77026797 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070087"
] | [
"APHC",
"FLJ11238",
"PHCA"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Lipid metabolism",
"Sphingolipid metabolism"
] | [
"Hydrolase"
] | [
"Disease variant",
"Leukodystrophy"
] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,402 | 4 |
ENSG00000078140 | UBE2K | Ubiquitin conjugating enzyme E2 K | [
"P61086"
] | 4 | 39698109-39782792 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028869",
"CAB033212",
"CAB033515"
] | [
"HIP2",
"HYPG",
"UBC1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Supported | null | 117 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 16: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 7: Non-specific - Transcription | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,403 | 5 |
ENSG00000078142 | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | [
"Q8NEB9"
] | 18 | 41955234-42087830 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040718"
] | [
"hVps34",
"Vps34"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Autophagy",
"Cell cycle",
"Cell division",
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | 45 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 13: Non-specific - Mixed function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,404 | 3 |
ENSG00000078177 | N4BP2 | NEDD4 binding protein 2 | [
"Q86UW6"
] | 4 | 40056797-40158252 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036770",
"HPA042607",
"HPA072549"
] | [
"B3BP"
] | [
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,405 | 8 |
ENSG00000078237 | TIGAR | TP53 induced glycolysis regulatory phosphatase | [
"Q9NQ88"
] | 12 | 4307763-4360028 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034010",
"HPA040354",
"HPA044111"
] | [
"C12orf5"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Autophagy"
] | [
"Hydrolase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 11 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 34: Testis cancer - Unknown function | Cluster 105: Non-specific - Mixed function | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 7 | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,406 | 5 |
ENSG00000078246 | TULP3 | TUB like protein 3 | [
"O75386"
] | 12 | 2877223-2941138 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015285",
"HPA018496"
] | [
"TUBL3"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein"
] | [
"Ciliopathy",
"Disease variant"
] | [
"Nucleoplasm",
"Primary cilium"
] | [
"Nucleoli",
"Plasma membrane",
"Mitotic spindle",
"Primary cilium transition zone",
"Basal body"
] | [
"Intracellular and membrane"
] | [
"Developmental protein"
] | Supported | Uncertain | null | 70 | Yes | null | Cluster 14: Non-specific - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 38: Non-specific - Transcription | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,407 | 3 |
ENSG00000078269 | SYNJ2 | Synaptojanin 2 | [
"O15056"
] | 6 | 157981863-158099176 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031575"
] | [
"INPP5H"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase",
"RNA-binding"
] | [] | [
"Microtubules"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 19 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 72: Neuronal - Signal transduction | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,408 | 5 |
ENSG00000078295 | ADCY2 | Adenylate cyclase 2 | [
"Q08462"
] | 5 | 7396138-7830081 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB031482",
"HPA038015",
"HPA038483"
] | [
"AC2",
"HBAC2",
"KIAA1060"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"cAMP biosynthesis"
] | [
"Lyase"
] | [] | [
"Golgi apparatus",
"Vesicles"
] | [
"Nuclear membrane",
"Primary cilium"
] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 25: Non-specific - Basic cellular processes | Group enriched | Detected in many | 7 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,409 | 3 |
ENSG00000078304 | PPP2R5C | Protein phosphatase 2 regulatory subunit B'gamma | [
"Q13362"
] | 14 | 101761709-101927989 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027553"
] | [
"B56G",
"B56gamma",
"PR61G"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | 28 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 51: Neurons - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 1,410 | 9 |
ENSG00000078328 | RBFOX1 | RNA binding fox-1 homolog 1 | [
"Q9NWB1"
] | 16 | 5239802-7713340 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040809",
"HPA066746",
"HPA075862"
] | [
"A2BP1",
"FOX-1",
"HRNBP1"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center",
"Golgi apparatus",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 33 | No | No | null | Cluster 53: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,411 | 8 |
ENSG00000078369 | GNB1 | G protein subunit beta 1 | [
"P62873"
] | 1 | 1785285-1892292 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040736",
"HPA074924"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [
"Transducer"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Plasma membrane"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Supported | null | 135 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 37: Non-specific - mRNA processing | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in all | 7 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,412 | 8 |
ENSG00000078399 | HOXA9 | Homeobox A9 | [
"P31269"
] | 7 | 27162438-27175180 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061982",
"HPA076200"
] | [
"HOX1",
"HOX1G"
] | [
"Cancer-related genes",
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 14 | null | null | Cluster 32: Basophils - Transcription | null | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 0 | 0 | 0 | [] | [] | [] | 1,413 | 8 |
ENSG00000078401 | EDN1 | Endothelin 1 | [
"P05305"
] | 6 | 12290361-12297194 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031976",
"HPA031978",
"CAB032500",
"CAB037291"
] | [
"ET1"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Vasoactive",
"Vasoconstrictor"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Other"
] | Approved | Approved | null | null | null | Yes | Cluster 25: Non-specific - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 15: Kidney cancer - Membrane components | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 6 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,414 | 4 |
ENSG00000078403 | MLLT10 | MLLT10 histone lysine methyltransferase DOT1L cofactor | [
"P55197"
] | 10 | 21524646-21743630 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005736",
"HPA005747",
"HPA072790"
] | [
"AF10"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 15 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,415 | 9 |
ENSG00000078487 | ZCWPW1 | Zinc finger CW-type and PWWP domain containing 1 | [
"Q9H0M4"
] | 7 | 100400826-100428992 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020911"
] | [
"DKFZp434N0510",
"FLJ10057",
"ZCW1"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | null | null | null | null | null | Cluster 22: Eosinophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 7 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 1,416 | 3 |
ENSG00000078549 | ADCYAP1R1 | ADCYAP receptor type I | [
"P41586"
] | 7 | 31052308-31111474 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030739",
"HPA049877"
] | [
"PAC1",
"PAC1R",
"PACAPR"
] | [
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Developmental protein",
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Vesicles"
] | [] | [] | [] | Enhanced | Enhanced | null | 1 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in many | 4 | Cancer enriched | Detected in some | 16 | Cancer enriched | Detected in some | 13 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,417 | 1 |
ENSG00000078579 | FGF20 | Fibroblast growth factor 20 | [
"Q9NP95"
] | 8 | 16992181-17002345 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Growth factor"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Growth factor"
] | null | null | null | null | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 5: Rhabdoid - Unknown function | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,418 | 7 |
ENSG00000078589 | P2RY10 | P2Y receptor family member 10 | [
"O00398"
] | X | 78945332-78963727 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA036757",
"HPA065766"
] | [
"P2Y10"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | Cluster 32: Basophils - Transcription | Cluster 9: Non-specific - Receptor signaling | Cluster 55: Lymphoma - Immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 17 | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 5 | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 1,419 | 9 |
ENSG00000078596 | ITM2A | Integral membrane protein 2A | [
"O43736"
] | X | 79360384-79367667 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000296"
] | [
"BRICD2A",
"E25A"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | Approved | null | null | 9 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 47: Endothelial cells - Vasculature | Cluster 59: Leukemia - T-cell receptor | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in all | null | Group enriched | Detected in many | 8 | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 6 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,420 | 1 |
ENSG00000078618 | NRDC | Nardilysin convertase | [
"O43847"
] | 1 | 51789191-51878805 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053661"
] | [
"hNRD1",
"hNRD2",
"NRD1"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 10 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,421 | 7 |
ENSG00000078668 | VDAC3 | Voltage dependent anion channel 3 | [
"Q9Y277"
] | 8 | 42391624-42405937 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026864"
] | [
"HD-VDAC3"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ion transport",
"Transport"
] | [
"Porin"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | 50 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 40: Non-specific - Unknown function | Cluster 47: Platelets - Hemostasis | Cluster 62: Skeletal muscle - Muscle contraction | Group enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,422 | 3 |
ENSG00000078674 | PCM1 | Pericentriolar material 1 | [
"Q15154"
] | 8 | 17922842-18029948 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023370",
"HPA023374",
"CAB058695"
] | [
"PTC4"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Microtubules",
"Primary cilium",
"Centriolar satellite",
"Basal body"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 189 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 55: Non-specific - Transcription | Cluster 40: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,423 | 5 |
ENSG00000078687 | TNRC6C | Trinucleotide repeat containing adaptor 6C | [
"Q9HCJ0"
] | 17 | 77958703-78108822 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA022007",
"HPA062051"
] | [
"FLJ20015",
"KIAA1582"
] | [
"Predicted intracellular proteins"
] | [
"RNA-mediated gene silencing",
"Translation regulation"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 50 | null | null | Cluster 41: Basophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 32: Retina & Lymphoid tissues - Signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 5 | 2 | 2 | 1 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,424 | 6 |
ENSG00000078699 | CBFA2T2 | CBFA2/RUNX1 partner transcriptional co-repressor 2 | [
"O43439"
] | 20 | 33490075-33650036 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA060523",
"HPA072433"
] | [
"MTGR1",
"ZMYND3"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Supported | null | 14 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 10: Ciliated cells - Ion channel activity | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 1,425 | 5 |
ENSG00000078725 | BRINP1 | BMP/retinoic acid inducible neural specific 1 | [
"O60477"
] | 9 | 119153458-119369435 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038828"
] | [
"DBC1",
"DBCCR1",
"FAM5A"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Cell cycle",
"Growth arrest",
"Neurogenesis"
] | [] | [] | [
"Microtubules"
] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | Uncertain | Approved | null | 6 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in many | 8 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,426 | 5 |
ENSG00000078747 | ITCH | Itchy E3 ubiquitin protein ligase | [
"Q96J02"
] | 20 | 34363235-34511773 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021126",
"HPA049032",
"CAB072824",
"CAB072825"
] | [
"AIP4"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Apoptosis",
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Enhanced | Supported | null | 141 | No | No | Cluster 35: Neutrophils - Protein binding | Cluster 11: White matter - Signal transduction | Cluster 62: Non-specific - Plasma proteins | Cluster 102: Non-specific - Mixed function | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,427 | 7 |
ENSG00000078795 | PKD2L2 | Polycystin 2 like 2, transient receptor potential cation channel | [
"Q9NZM6"
] | 5 | 137887968-137942747 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA041903",
"HPA043634"
] | [
"TRPP5"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel"
] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 34: Non-specific - Mixed function | Cluster 56: Non-specific - Sensory perception | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 57: Testis - Spermatogenesis | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 1,428 | 1 |
ENSG00000078804 | TP53INP2 | Tumor protein p53 inducible nuclear protein 2 | [
"Q8IXH6"
] | 20 | 34704339-34713439 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"C20orf110",
"dJ1181N3.1",
"DKFZp434B2411",
"DKFZp434O0827",
"DOR",
"FLJ21759",
"FLJ23500",
"PINH"
] | [
"Predicted intracellular proteins"
] | [
"Autophagy",
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [] | [] | [] | [] | null | null | null | 3 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 6: Non-specific - Immune response | Cluster 27: Breast cancer - Unknown function | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in all | 10 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 4 | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 1,429 | 4 |
ENSG00000078808 | SDF4 | Stromal cell derived factor 4 | [] | 1 | 1216931-1232031 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA011249",
"HPA011895",
"CAB015227"
] | [
"Cab45"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [
"Intracellular and membrane"
] | [] | Supported | Supported | Supported | 6 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 37: Non-specific - mRNA processing | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,430 | 1 |
ENSG00000078814 | MYH7B | Myosin heavy chain 7B | [
"A7E2Y1"
] | 20 | 34955810-35002437 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"dJ756N5.1",
"KIAA1512",
"MHC14",
"MYH14"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Motor protein",
"Muscle protein",
"Myosin"
] | [] | [] | [] | [] | [] | null | null | null | 5 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 32: Non-specific - Cell proliferation | Cluster 55: Myocytes - Oxidative muscle function | Cluster 41: Striated muscle - Muscle contraction | Group enriched | Detected in many | 9 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 1,431 | 1 |
ENSG00000078898 | BPIFB2 | BPI fold containing family B member 2 | [
"Q8N4F0"
] | 20 | 33007704-33023703 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049491",
"HPA060121"
] | [
"BPIL1",
"C20orf184",
"dJ726C3.2",
"LPLUNC2"
] | [
"Plasma proteins",
"Predicted secreted proteins",
"Transporters"
] | [] | [] | [] | [
"Vesicles"
] | [] | [
"Secreted in other tissues"
] | [
"No annotated function"
] | Approved | Enhanced | null | 2 | null | null | null | null | Cluster 27: Breast cancer - Unknown function | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 82: Salivary gland - Secretion | Tissue enriched | Detected in some | 26 | Group enriched | Detected in some | 9 | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,432 | 9 |
ENSG00000078900 | TP73 | Tumor protein p73 | [
"O15350"
] | 1 | 3652516-3736201 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002514",
"CAB003022",
"HPA027314",
"HPA044516"
] | [
"P73"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Apoptosis",
"Cell cycle",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Ciliopathy",
"Disease variant",
"Lissencephaly",
"Primary ciliary dyskinesia",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Vesicles",
"Plasma membrane",
"Cell Junctions",
"Centrosome",
"Basal body"
] | [] | [] | Supported | Enhanced | null | 76 | null | Yes | null | Cluster 50: Non-specific - Nucleic acid binding | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 1,433 | 2 |
ENSG00000078902 | TOLLIP | Toll interacting protein | [
"Q9H0E2"
] | 11 | 1274371-1309654 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038621",
"HPA038622"
] | [
"IL-1RAcPIP"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Autophagy",
"Immunity",
"Inflammatory response",
"Innate immunity"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Primary cilium",
"Primary cilium tip"
] | [] | [] | Supported | Enhanced | null | 105 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 51: Neurons - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,434 | 8 |
ENSG00000079101 | CLUL1 | Clusterin like 1 | [
"Q15846"
] | 18 | 596988-650334 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"CAB025264",
"HPA075240"
] | [] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [
"Plasma membrane"
] | [
"Secreted in other tissues"
] | [
"No annotated function"
] | Approved | Enhanced | null | null | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 11: White matter - Signal transduction | Cluster 11: Neuronal - Sensory perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in many | 10 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 12 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,436 | 6 |
ENSG00000079102 | RUNX1T1 | RUNX1 partner transcriptional co-repressor 1 | [
"Q06455"
] | 8 | 91954972-92103286 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049852",
"HPA070951"
] | [
"AML1T1",
"CBFA2T1",
"CDR",
"ETO",
"MTG8",
"ZMYND2"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 27 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 37: Non-specific - mRNA processing | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,437 | 1 |
ENSG00000079112 | CDH17 | Cadherin 17 | [
"Q12864"
] | 8 | 94127162-94217303 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023614",
"HPA023616",
"CAB025143",
"HPA026556"
] | [
"cadherin",
"HPT-1"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Transport"
] | [] | [
"Cancer-related genes"
] | [
"Cell Junctions"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 48: Non-specific - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enriched | Detected in some | 11 | Group enriched | Detected in many | 5 | Group enriched | Detected in many | 7 | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in some | 5 | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,438 | 1 |
ENSG00000079134 | THOC1 | THO complex subunit 1 | [
"Q96FV9"
] | 18 | 214520-268050 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019096",
"HPA019687"
] | [
"HPR1",
"P84"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"mRNA processing",
"mRNA splicing",
"mRNA transport",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"DNA-binding",
"RNA-binding"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Nuclear speckles"
] | [] | [] | [] | Enhanced | Enhanced | null | 75 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 11: White matter - Signal transduction | Cluster 13: Non-specific - Mixed function | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,439 | 5 |
ENSG00000079150 | FKBP7 | FKBP prolyl isomerase 7 | [
"Q9Y680"
] | 2 | 178463664-178478600 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008707"
] | [
"FKBP23"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Isomerase",
"Rotamase"
] | [] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Approved | Supported | 61 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 9: Non-specific - Receptor signaling | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Stomach Adenocarcinoma"
] | [
"Stomach Adenocarcinoma"
] | 1,440 | 7 |
ENSG00000079156 | OSBPL6 | Oxysterol binding protein like 6 | [
"Q9BZF3"
] | 2 | 178194481-178402893 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA032131"
] | [
"ORP6"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 15 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 71: Lymphoma - Inflammatory response | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,441 | 5 |
ENSG00000079215 | SLC1A3 | Solute carrier family 1 member 3 | [
"P43003"
] | 5 | 36596588-36688334 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002573",
"HPA037467",
"HPA037468"
] | [
"EA6",
"EAAT1",
"GLAST",
"GLAST-1",
"GLAST1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Symport",
"Transport"
] | [] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoli",
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | Supported | 20 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in all | 8 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in all | 23 | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 9 | 0 | 0 | 0 | [] | [] | [] | 1,442 | 5 |
ENSG00000079246 | XRCC5 | X-ray repair cross complementing 5 | [
"P13010"
] | 2 | 216107464-216206303 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004468",
"HPA025813",
"HPA064685"
] | [
"KARP-1",
"KU80",
"Ku86",
"KUB2"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA recombination",
"DNA repair",
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Ribosome biogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Helicase",
"Hydrolase"
] | [
"Cancer-related genes",
"Systemic lupus erythematosus"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 182 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 34: Non-specific - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 4 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,443 | 6 |
ENSG00000079257 | LXN | Latexin | [
"Q9BS40"
] | 3 | 158645822-158672648 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014179",
"CAB025128"
] | [] | [
"Predicted intracellular proteins"
] | [
"Inflammatory response"
] | [
"Heparin-binding",
"Metalloenzyme inhibitor",
"Metalloprotease inhibitor",
"Protease inhibitor"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 21 | No | null | Cluster 35: Neutrophils - Protein binding | Cluster 48: Non-specific - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,444 | 4 |
ENSG00000079263 | SP140 | SP140 nuclear body protein | [
"Q13342"
] | 2 | 230203110-230313215 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006162",
"HPA067493"
] | [
"LYSP100-A",
"LYSP100-B"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Mitochondria"
] | [] | [] | Approved | Enhanced | null | 4 | null | null | Cluster 24: Non-specific - Transcription | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 18: Lymphoid tissue - Immune response | Group enriched | Detected in many | 5 | Group enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 1,445 | 7 |
ENSG00000079277 | MKNK1 | MAPK interacting serine/threonine kinase 1 | [
"Q9BUB5"
] | 1 | 46557407-46616843 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB027355",
"CAB037310",
"HPA071293"
] | [
"MNK1"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Translation regulation"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 16 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 48: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,446 | 9 |
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