ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000073754 | CD5L | CD5 molecule like | [
"O43866"
] | 1 | 157830911-157898256 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065686",
"HPA068384"
] | [
"API6",
"Spalpha"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Apoptosis",
"Immunity",
"Inflammatory response"
] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Immunity"
] | null | Enhanced | null | null | null | null | null | null | Cluster 51: Myeloma - Immunoglobulins | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 66: Lymphoid tissue - Immune response | Tissue enriched | Detected in some | 6 | Not detected | Not detected | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,231 | 8 |
ENSG00000073756 | PTGS2 | Prostaglandin-endoperoxide synthase 2 | [
"P35354"
] | 1 | 186671791-186680922 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000113",
"HPA001335",
"CAB080135"
] | [
"COX2"
] | [
"Cancer-related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Prostaglandin biosynthesis",
"Prostaglandin metabolism"
] | [
"Dioxygenase",
"Oxidoreductase",
"Peroxidase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Vesicles"
] | [
"Cytosol"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Enhanced | null | 10 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 53: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 16 | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 1,232 | 6 |
ENSG00000073792 | IGF2BP2 | Insulin like growth factor 2 mRNA binding protein 2 | [
"Q9Y6M1"
] | 3 | 185643130-185825042 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017126",
"HPA035145"
] | [
"IMP-2",
"p62"
] | [
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA transport",
"Translation regulation",
"Transport"
] | [
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 56 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 25: Non-specific - Transcription | Cluster 72: Neuronal - Signal transduction | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 5 | 2 | 4 | [
"Lung Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,233 | 6 |
ENSG00000073803 | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13 | [
"O43283"
] | 3 | 185282941-185489094 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016497",
"HPA036691",
"HPA036692"
] | [
"LZK",
"MEKK13"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Centriolar satellite"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 18: Non-specific - Translation | Cluster 37: Neurons - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 36: Brain & Liver - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,234 | 3 |
ENSG00000073849 | ST6GAL1 | ST6 beta-galactoside alpha-2,6-sialyltransferase 1 | [
"P15907"
] | 3 | 186930325-187078553 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB080031"
] | [
"CDw75",
"SIAT1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Enhanced | null | null | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 20: Myeloma - Immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 45: Liver - Metabolism & Coagulation | Group enriched | Detected in all | 5 | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 1,235 | 1 |
ENSG00000073861 | TBX21 | T-box transcription factor 21 | [
"Q9UL17"
] | 17 | 47733236-47746122 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009524",
"CAB030043"
] | [
"T-bet",
"TBLYM"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Asthma",
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 4 | null | null | Cluster 15: NK-cells - Unknown function | null | Cluster 55: Lymphoma - Immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 66: Lymphoid tissue - Immune response | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 15 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 14 | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,236 | 4 |
ENSG00000073910 | FRY | FRY microtubule binding protein | [
"Q5TBA9"
] | 13 | 31846713-32299125 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041635"
] | [
"13CDNA73",
"bA37E23.1",
"C13orf14",
"CG003"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 22: Eosinophils - Transcription | Cluster 35: Non-specific - DNA binding | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 8 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,237 | 2 |
ENSG00000073921 | PICALM | Phosphatidylinositol binding clathrin assembly protein | [
"Q13492"
] | 11 | 85957175-86069882 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019053",
"HPA019061"
] | [
"CALM",
"CLTH"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Vesicles"
] | [] | [] | [] | Enhanced | Enhanced | null | 45 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 47: Leukemia - Hemostasis | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,238 | 6 |
ENSG00000073969 | NSF | N-ethylmaleimide sensitive factor, vesicle fusing ATPase | [
"P46459"
] | 17 | 46590669-46757679 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003154",
"CAB009324",
"HPA071089"
] | [
"SEC18",
"SKD2"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Golgi apparatus",
"Cytosol"
] | [
"Acrosome",
"Equatorial segment",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Supported | Enhanced | null | 102 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 102: Non-specific - Mixed function | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | 1,239 | 6 |
ENSG00000074047 | GLI2 | GLI family zinc finger 2 | [
"P10070"
] | 2 | 120735623-120992653 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB008558",
"HPA074275"
] | [
"HPE9",
"THP1",
"THP2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding",
"Repressor"
] | [
"Disease variant",
"Holoprosencephaly"
] | [
"Nucleoli"
] | [
"Nucleoplasm",
"Centrosome",
"Basal body"
] | [] | [] | Supported | Approved | null | 10 | No | No | null | Cluster 44: Non-specific - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 1,240 | 2 |
ENSG00000074054 | CLASP1 | Cytoplasmic linker associated protein 1 | [
"Q7Z460"
] | 2 | 121337776-121649476 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA065219"
] | [
"KIAA0622",
"MAST1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 66 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 1,241 | 2 |
ENSG00000074071 | MRPS34 | Mitochondrial ribosomal protein S34 | [
"P82930"
] | 16 | 1771890-1773150 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042112"
] | [
"MGC2616",
"MRP-S12"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Supported | null | 107 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 27: Non-specific - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,242 | 3 |
ENSG00000074201 | CLNS1A | Chloride nucleotide-sensitive channel 1A | [
"P54105"
] | 11 | 77514936-77637794 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017840",
"HPA031707",
"HPA031708",
"HPA032045"
] | [
"CLCI",
"ICln"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Microtubules",
"Primary cilium",
"Connecting piece",
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Approved | null | 119 | No | No | Cluster 13: Non-specific - Mitochondria | Cluster 55: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 15: Non-specific - Protein processing | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,244 | 3 |
ENSG00000074211 | PPP2R2C | Protein phosphatase 2 regulatory subunit Bgamma | [
"Q9Y2T4"
] | 4 | 6320578-6563600 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042122",
"HPA042770",
"HPA060473"
] | [
"B55gamma",
"IMYPNO",
"MGC33570",
"PR52",
"PR55G"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 24 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 7: Liver cancer - Metabolism | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,245 | 3 |
ENSG00000074219 | TEAD2 | TEA domain transcription factor 2 | [
"Q15562"
] | 19 | 49340595-49362457 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066292",
"HPA069963"
] | [
"ETF",
"TEF-4",
"TEF4"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 12 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 42: Choroid plexus - Mitochondria | Cluster 5: Rhabdoid - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 22 | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,246 | 3 |
ENSG00000074266 | EED | Embryonic ectoderm development | [
"O75530"
] | 11 | 86201212-86278813 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB012211",
"HPA046731",
"HPA061140"
] | [
"HEED",
"WAIT-1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Repressor"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 96 | null | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,247 | 7 |
ENSG00000074317 | SNCB | Synuclein beta | [
"Q16143"
] | 5 | 176620082-176630556 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002681",
"HPA035876"
] | [] | [
"Human disease related genes",
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | Supported | 9 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in some | 25 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in some | 8 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,249 | 5 |
ENSG00000074319 | TSG101 | Tumor susceptibility 101 | [
"Q99816"
] | 11 | 18468336-18526951 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004283",
"HPA006161"
] | [
"TSG10",
"VPS23"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Growth regulation",
"Host-virus interaction",
"Protein transport",
"Transport"
] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Nucleoli",
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 153 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,250 | 6 |
ENSG00000074356 | NCBP3 | Nuclear cap binding subunit 3 | [
"Q53F19"
] | 17 | 3802158-3846246 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008959",
"HPA013195"
] | [
"C17orf85",
"ELG",
"HSA277841"
] | [
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"mRNA capping",
"mRNA processing",
"mRNA transport",
"Transport"
] | [
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Supported | null | 39 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 11: White matter - Signal transduction | Cluster 42: Non-specific - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 1,251 | 9 |
ENSG00000074370 | ATP2A3 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 | [
"Q93084"
] | 17 | 3923870-3964464 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007180",
"CAB010882"
] | [
"SERCA3"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Translocase"
] | [] | [] | [] | [] | [] | null | Approved | null | 14 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 38: Sub-cortical - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 95: Tuft cells - Chemosensory signaling | Cluster 34: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,252 | 9 |
ENSG00000074416 | MGLL | Monoglyceride lipase | [
"Q99685"
] | 3 | 127689062-128052190 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011347",
"HPA011993",
"HPA011994"
] | [
"HU-K5",
"MAGL",
"MGL"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase",
"Serine esterase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 4 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 64: Connective tissue cells - ECM organization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 1,254 | 5 |
ENSG00000074527 | NTN4 | Netrin 4 | [
"Q9HB63"
] | 12 | 95657807-95791189 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049832"
] | [] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | null | Approved | null | 9 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 12 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,255 | 7 |
ENSG00000074582 | BCS1L | BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone | [
"Q9Y276"
] | 2 | 218658764-218663443 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037700",
"HPA037701"
] | [
"BCS",
"BJS",
"h-BCS",
"Hs.6719"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Chaperone",
"Hydrolase"
] | [
"Deafness",
"Disease variant",
"Primary mitochondrial disease"
] | [
"Vesicles"
] | [
"Mid piece"
] | [] | [] | Uncertain | Supported | null | 12 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 49: Hindbrain - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 97: Non-specific - Cellular respiration | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,256 | 2 |
ENSG00000074590 | NUAK1 | NUAK family kinase 1 | [
"O60285"
] | 12 | 106063345-106138954 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057143"
] | [
"ARK5",
"KIAA0537"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion",
"DNA damage"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm",
"Microtubules",
"Mitotic spindle",
"Primary cilium"
] | [] | [] | Supported | null | null | 21 | Yes | No | null | Cluster 53: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 1,257 | 3 |
ENSG00000074603 | DPP8 | Dipeptidyl peptidase 8 | [
"Q6V1X1"
] | 15 | 65442463-65517704 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008706"
] | [
"DP8",
"DPRP1",
"FLJ14920",
"FLJ20283",
"MGC26191",
"MSTP141"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Aminopeptidase",
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 3 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,258 | 4 |
ENSG00000074621 | SLC24A1 | Solute carrier family 24 member 1 | [
"O60721"
] | 15 | 65611366-65660995 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039370"
] | [
"CSNB1D",
"HsT17412",
"KIAA0702",
"NCKX",
"NCKX1",
"RODX"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Calcium transport",
"Ion transport",
"Sensory transduction",
"Symport",
"Transport",
"Vision"
] | [] | [
"Congenital stationary night blindness"
] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 14: Non-specific - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in many | 34 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,259 | 7 |
ENSG00000074657 | ZNF532 | Zinc finger protein 532 | [
"Q9HCE3"
] | 18 | 58862600-58986480 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015322"
] | [
"FLJ10697"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 6: Non-specific - Immune response | Cluster 13: Non-specific - Mixed function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 1,260 | 1 |
ENSG00000074660 | SCARF1 | Scavenger receptor class F member 1 | [
"Q14162"
] | 17 | 1633858-1645744 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035108",
"HPA072936"
] | [
"KIAA0149",
"SREC",
"SREC1"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Receptor"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Enhanced | null | 18 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Not detected | Not detected | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,261 | 1 |
ENSG00000074695 | LMAN1 | Lectin, mannose binding 1 | [
"P49257"
] | 18 | 59327823-59359265 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002320",
"CAB037163"
] | [
"ERGIC-53",
"ERGIC53",
"F5F8D",
"FMFD1",
"gp58",
"MCFD1",
"MR60"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [
"Endoplasmic reticulum"
] | [] | [] | Supported | Supported | null | 49 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 55: Non-specific - Transcription | Cluster 13: Non-specific - Mixed function | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,262 | 8 |
ENSG00000074696 | HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | [
"Q9P035"
] | 15 | 65530418-65578349 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014837",
"HPA060347"
] | [
"B-ind1",
"HSPC121",
"PTPLAD1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Lyase"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Enhanced | Enhanced | null | 32 | null | null | Cluster 24: Non-specific - Transcription | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 58: Non-specific - Nuclear processes | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,263 | 6 |
ENSG00000074706 | IPCEF1 | Interaction protein for cytohesin exchange factors 1 | [
"Q8WWN9"
] | 6 | 154154496-154356803 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028708",
"HPA028710"
] | [
"KIAA0403",
"PIP3-E"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear speckles",
"Plasma membrane"
] | [
"Nucleoli",
"Cytoplasmic bodies"
] | [] | [] | Approved | Supported | null | 11 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 53: Neurons - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in many | 8 | Group enriched | Detected in some | 9 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,264 | 6 |
ENSG00000074755 | ZZEF1 | Zinc finger ZZ-type and EF-hand domain containing 1 | [
"O43149"
] | 17 | 4004445-4143030 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031778",
"HPA031790"
] | [
"FLJ10821",
"KIAA0399",
"ZZZ4"
] | [
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoplasm"
] | [
"Mitochondria"
] | [] | [] | Approved | Uncertain | null | 23 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 42: Choroid plexus - Mitochondria | Cluster 42: Non-specific - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,265 | 6 |
ENSG00000074771 | NOX3 | NADPH oxidase 3 | [
"Q9HBY0"
] | 6 | 155395368-155455839 | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | Evidence at protein level | [
"HPA073837"
] | [
"GP91-3"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Oxidoreductase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | null | null | 1 | null | null | null | null | Cluster 5: Rhabdoid - Unknown function | Cluster 58: Mast cells - Allergic inflammatory responses | null | Not detected | Not detected | null | Cancer enriched | Detected in some | 8 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,266 | 3 |
ENSG00000074800 | ENO1 | Enolase 1 | [
"P06733"
] | 1 | 8861000-8879190 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018614",
"HPA068284",
"HPA068721",
"CAB069394",
"CAB080034"
] | [
"ENO1L1",
"MBP-1",
"MPB1",
"PPH"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Glycolysis",
"Plasminogen activation",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Lyase",
"Repressor"
] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | 95 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 15: Kidney cancer - Membrane components | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 7 | 2 | 6 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,267 | 7 |
ENSG00000074803 | SLC12A1 | Solute carrier family 12 member 1 | [
"Q13621"
] | 15 | 48178438-48304078 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014967",
"HPA018107"
] | [
"BSC",
"BSC-1",
"BSC1",
"CCC2",
"NKCC2"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Symport",
"Transport"
] | [] | [
"Bartter syndrome",
"Disease variant",
"FDA approved drug targets",
"Neurodegeneration"
] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in single | 826 | Not detected | Not detected | null | Group enriched | Detected in some | 6 | Cell type enriched | Detected in many | 29 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,268 | 6 |
ENSG00000074842 | MYDGF | Myeloid derived growth factor | [
"Q969H8"
] | 19 | 4641374-4670362 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041872",
"HPA046744"
] | [
"C19orf10",
"IL-25",
"IL-27",
"IL25",
"IL27",
"IL27w",
"R33729_1",
"SF20"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Angiogenesis",
"Apoptosis"
] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Developmental protein"
] | null | Approved | null | 16 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,269 | 5 |
ENSG00000074855 | ANO8 | Anoctamin 8 | [
"Q9HCE9"
] | 19 | 17323223-17334855 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049206"
] | [
"KIAA1623",
"TMEM16H"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 1,270 | 4 |
ENSG00000074935 | TUBE1 | Tubulin epsilon 1 | [
"Q9UJT0"
] | 6 | 112070663-112087529 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA032073",
"HPA032074"
] | [
"dJ142L7.2",
"FLJ22589",
"TUBE"
] | [
"FDA approved drug targets",
"Predicted intracellular proteins"
] | [] | [] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | 2 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 55: Non-specific - Transcription | Cluster 13: Non-specific - Mixed function | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 31: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 1,271 | 5 |
ENSG00000074964 | ARHGEF10L | Rho guanine nucleotide exchange factor 10 like | [
"Q9HCE6"
] | 1 | 17539698-17697874 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026426",
"HPA026440",
"HPA028115"
] | [
"FLJ10521",
"KIAA1626"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Golgi apparatus",
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 25: Non-specific - Transcription | Cluster 10: Ciliated cells - Ion channel activity | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 41 | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,272 | 6 |
ENSG00000074966 | TXK | TXK tyrosine kinase | [
"P42681"
] | 4 | 48066393-48134250 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA078636"
] | [
"BTKL",
"PSCTK5",
"PTK4",
"RLK",
"TKL"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Immunity",
"Transcription",
"Transcription regulation"
] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nucleoli",
"Plasma membrane"
] | [] | [] | Supported | null | null | 18 | null | null | Cluster 24: Non-specific - Transcription | Cluster 49: Hindbrain - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,273 | 6 |
ENSG00000075035 | WSCD2 | WSC domain containing 2 | [
"Q2TBF2"
] | 12 | 108129288-108250537 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA013346",
"HPA048133"
] | [
"KIAA0789"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Approved | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in many | 7 | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,274 | 5 |
ENSG00000075043 | KCNQ2 | Potassium voltage-gated channel subfamily Q member 2 | [
"O43526"
] | 20 | 63400208-63472677 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016642",
"HPA057112"
] | [
"BFNC",
"EBN",
"EBN1",
"ENB1",
"HNSPC",
"KCNA11",
"Kv7.2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in some | 10 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,275 | 9 |
ENSG00000075073 | TACR2 | Tachykinin receptor 2 | [
"P21452"
] | 10 | 69403903-69416918 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA076573"
] | [
"NK2R",
"NKNAR",
"SKR",
"TAC2R"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | null | null | 1 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,276 | 6 |
ENSG00000075089 | ACTR6 | Actin related protein 6 | [
"Q9GZN1"
] | 12 | 100199122-100241865 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038587",
"HPA038588"
] | [
"ARP6",
"FLJ13433"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Repressor"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 24 | No | No | Cluster 3: Non-specific - Nuclear processes | Cluster 27: Non-specific - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,277 | 2 |
ENSG00000075131 | TIPIN | TIMELESS interacting protein | [
"Q9BVW5"
] | 15 | 66336191-66386746 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039704",
"HPA058799"
] | [
"FLJ20516"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"Mitosis"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 14 | null | Yes | Cluster 33: Non-specific - ATP binding | Cluster 2: Neurons - Nucleosome | Cluster 58: Non-specific - Nuclear processes | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,278 | 4 |
ENSG00000075142 | SRI | Sorcin | [
"P30626"
] | 7 | 88205115-88226993 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019004",
"HPA073666"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 15 | No | No | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 39: Non-specific - Transcription | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,279 | 5 |
ENSG00000075151 | EIF4G3 | Eukaryotic translation initiation factor 4 gamma 3 | [
"O43432"
] | 1 | 20806292-21177285 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025031",
"HPA025039",
"HPA025041"
] | [
"eIF4GII"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis",
"Translation regulation"
] | [
"Initiation factor",
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 34 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,280 | 2 |
ENSG00000075213 | SEMA3A | Semaphorin 3A | [
"Q14563"
] | 7 | 83955777-84492724 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029447",
"HPA052235"
] | [
"coll-1",
"Hsema-I",
"SEMA1",
"SEMAD",
"SemD"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [
"Disease variant",
"Hypogonadotropic hypogonadism",
"Kallmann syndrome"
] | [
"Vesicles"
] | [] | [
"Secreted in other tissues"
] | [
"Developmental protein"
] | Approved | Approved | null | null | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 9: Non-specific - Receptor signaling | Cluster 5: Rhabdoid - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 42: Retina - Visual perception | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 1,282 | 8 |
ENSG00000075218 | GTSE1 | G2 and S-phase expressed 1 | [
"Q9NYZ3"
] | 22 | 46296870-46330810 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029457"
] | [
"B99",
"GTSE-1",
"Lnc_bc060912"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Centrosome"
] | [
"Nucleoplasm",
"Primary cilium",
"Primary cilium tip",
"Basal body",
"Cytosol"
] | [] | [] | Supported | null | null | 21 | Yes | Yes | Cluster 15: NK-cells - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 66: Non-specific - Mitochondria | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 7 | 6 | 4 | [
"Breast Invasive Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,283 | 3 |
ENSG00000075223 | SEMA3C | Semaphorin 3C | [
"Q99985"
] | 7 | 80742538-80922359 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA042418"
] | [
"SEMAE",
"SemE"
] | [
"Predicted secreted proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [] | [
"Golgi apparatus",
"Cytosol"
] | [
"Plasma membrane"
] | [
"Secreted in other tissues"
] | [
"Developmental protein"
] | Approved | null | null | 14 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 49: Hindbrain - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 9 | 4 | 0 | 4 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,284 | 4 |
ENSG00000075234 | TTC38 | Tetratricopeptide repeat domain 38 | [
"Q5R3I4"
] | 22 | 46267961-46294008 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029302",
"HPA075893"
] | [
"FLJ20699"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 46: Brainstem - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,285 | 6 |
ENSG00000075239 | ACAT1 | Acetyl-CoA acetyltransferase 1 | [
"P24752"
] | 11 | 108116695-108147603 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004428",
"HPA007569"
] | [
"ACAT",
"THIL"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 15 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 24: Non-specific - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,286 | 3 |
ENSG00000075240 | GRAMD4 | GRAM domain containing 4 | [
"Q6IC98"
] | 22 | 46576012-46679790 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"DIP",
"KIAA0767"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [] | [] | [] | [] | [] | [] | null | null | null | 12 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 51: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 0 | 5 | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,287 | 7 |
ENSG00000075275 | CELSR1 | Cadherin EGF LAG seven-pass G-type receptor 1 | [
"Q9NYQ6"
] | 22 | 46360834-46537620 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052976",
"HPA060521"
] | [
"ADGRC1",
"CDHF9",
"FMI2",
"HFMI2",
"ME2"
] | [
"Disease related genes",
"G-protein coupled receptors",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Developmental protein",
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [
"Intracellular and membrane"
] | [
"Receptor"
] | Enhanced | null | null | 1 | null | null | Cluster 34: B-cells - Unknown function | Cluster 46: Brainstem - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,288 | 8 |
ENSG00000075290 | WNT8B | Wnt family member 8B | [
"Q93098"
] | 10 | 100463009-100483744 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA036570"
] | [] | [
"Predicted secreted proteins"
] | [
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | null | Uncertain | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 71: Lymphoma - Inflammatory response | Cluster 89: Adipocytes - Lipid metabolism | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,289 | 3 |
ENSG00000075292 | ZNF638 | Zinc finger protein 638 | [
"Q14966"
] | 2 | 71276561-71435069 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036784",
"HPA057395"
] | [
"MGC26130",
"NP220",
"ZFML",
"Zfp638"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | Supported | null | 37 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 55: Myocytes - Oxidative muscle function | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,290 | 8 |
ENSG00000075303 | SLC25A40 | Solute carrier family 25 member 40 | [
"Q8TBP6"
] | 7 | 87833568-87876360 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055197"
] | [
"MCFP"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 25 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 37: Neurons - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,291 | 8 |
ENSG00000075340 | ADD2 | Adducin 2 | [
"P35612"
] | 2 | 70607618-70768225 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009796",
"HPA034509",
"HPA034510"
] | [
"ADDB"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Calmodulin-binding"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Supported | null | 8 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 24: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 109: Neurons - Neuronal signaling | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 1,293 | 5 |
ENSG00000075391 | RASAL2 | RAS protein activator like 2 | [
"Q9UJF2"
] | 1 | 178094104-178484147 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018805",
"HPA020453"
] | [
"nGAP"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Plasma membrane",
"Focal adhesion sites"
] | [] | [] | [] | Approved | Enhanced | null | 35 | null | Yes | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 72: Neuronal - Signal transduction | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,295 | 8 |
ENSG00000075399 | VPS9D1 | VPS9 domain containing 1 | [
"Q9Y2B5"
] | 16 | 89707134-89720898 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007847",
"HPA023620"
] | [
"ATP-BL",
"C16orf7"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 26 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 32: Cerebral cortex - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 8 | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,296 | 9 |
ENSG00000075407 | ZNF37A | Zinc finger protein 37A | [
"P17032"
] | 10 | 38094334-38150293 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA003172"
] | [
"KOX21",
"ZNF37"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 24: Non-specific - Transcription | Cluster 9: Non-specific - Receptor signaling | Cluster 52: Non-specific - Mitochondria | Cluster 78: Plasma cells - Antibody production & ER-stress response | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,297 | 3 |
ENSG00000075413 | MARK3 | Microtubule affinity regulating kinase 3 | [
"P27448"
] | 14 | 103385377-103503831 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024652"
] | [
"CTAK1",
"KP78",
"PAR-1A"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 59 | null | null | Cluster 19: Eosinophils - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 30: Non-specific - Gene expression regulation | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Immune cell enriched | Detected in many | 32 | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,298 | 2 |
ENSG00000075415 | SLC25A3 | Solute carrier family 25 member 3 | [
"Q00325"
] | 12 | 98593591-98606379 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045709"
] | [
"PHC"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Symport",
"Transport"
] | [] | [
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | null | null | 25 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 38: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,299 | 4 |
ENSG00000075420 | FNDC3B | Fibronectin type III domain containing 3B | [
"Q53EP0"
] | 3 | 172039578-172401669 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007859"
] | [
"DKFZp762K137",
"FAD104",
"FLJ23399",
"PRO4979",
"YVTM2421"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Uncertain | null | 6 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 12: Non-specific - Vasculature | Cluster 63: Non-specific - Protein processing | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 4 | 2 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,300 | 5 |
ENSG00000075426 | FOSL2 | FOS like 2, AP-1 transcription factor subunit | [
"P15408"
] | 2 | 28392448-28417317 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004817",
"CAB013460",
"HPA061417"
] | [
"FLJ23306",
"FRA2"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Disease variant",
"Ectodermal dysplasia"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 49 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 29: Forebrain - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 103: Non-specific - Basic cellular processes | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 1,301 | 8 |
ENSG00000075429 | CACNG5 | Calcium voltage-gated channel auxiliary subunit gamma 5 | [
"Q9UF02"
] | 17 | 66835117-66894751 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA050115"
] | [] | [
"FDA approved drug targets",
"Predicted membrane proteins"
] | [] | [] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 46: Brain & retina - Neuronal signaling | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,302 | 8 |
ENSG00000075461 | CACNG4 | Calcium voltage-gated channel auxiliary subunit gamma 4 | [
"Q9UBN1"
] | 17 | 66964707-67033398 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005803",
"HPA065370"
] | [
"MGC11138",
"MGC24983"
] | [
"FDA approved drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Voltage-gated channel"
] | [
"FDA approved drug targets"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 28 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,303 | 9 |
ENSG00000075568 | TMEM131 | Transmembrane protein 131 | [
"Q92545"
] | 2 | 97756333-97995948 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017678",
"HPA017682"
] | [
"CC28",
"KIAA0257",
"PRO1048",
"RW1",
"YR-23"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles",
"Intermediate filaments"
] | [] | [] | [] | Uncertain | Approved | null | 32 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 55: Lymphoma - Immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,305 | 3 |
ENSG00000075618 | FSCN1 | Fascin actin-bundling protein 1 | [
"Q16658"
] | 7 | 5592816-5606655 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000121",
"HPA005723",
"CAB035991",
"HPA050654",
"CAB080327"
] | [
"FLJ38511",
"p55",
"SNL"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 24 | null | Yes | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 11: White matter - Signal transduction | Cluster 67: Non-specific - Unknown function | Cluster 82: Dendritic cells - Antigen presentation | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 2 | 1 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,306 | 6 |
ENSG00000075624 | ACTB | Actin beta | [
"P60709"
] | 7 | 5526409-5563902 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002621",
"HPA041264",
"HPA041271"
] | [] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Deafness",
"Disease variant",
"Dystonia",
"Intellectual disability"
] | [] | [] | [] | [] | null | Supported | null | 444 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 27: Non-specific - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 47: Platelets - Hemostasis | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,307 | 1 |
ENSG00000075643 | MOCOS | Molybdenum cofactor sulfurase | [
"Q96EN8"
] | 18 | 36187497-36272157 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039412",
"HPA047958"
] | [
"FLJ20733",
"HMCS",
"MOS"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Molybdenum cofactor biosynthesis"
] | [
"Transferase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 8 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Colon Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,308 | 1 |
ENSG00000075651 | PLD1 | Phospholipase D1 | [
"Q13393"
] | 3 | 171600404-171810950 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004527",
"HPA013555",
"HPA042396"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | Approved | Enhanced | null | 30 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 11: White matter - Signal transduction | Cluster 5: Rhabdoid - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,309 | 5 |
ENSG00000075673 | ATP12A | ATPase H+/K+ transporting non-gastric alpha2 subunit | [
"P54707"
] | 13 | 24680408-24712472 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039526"
] | [
"ATP1AL1",
"H-K-ATPase",
"HK"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Hydrogen ion transport",
"Ion transport",
"Potassium transport",
"Sodium transport",
"Transport"
] | [
"Translocase"
] | [] | [
"Plasma membrane",
"Actin filaments"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | null | null | null | null | null | Cluster 55: Lymphoma - Immune response | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in some | 4 | Cancer enriched | Detected in single | 6 | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 1,310 | 3 |
ENSG00000075702 | WDR62 | WD repeat domain 62 | [
"O43379"
] | 19 | 36054649-36105108 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043255",
"HPA043639"
] | [
"C19orf14",
"DKFZP434J046",
"FLJ33298",
"MCPH2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Neurogenesis"
] | [] | [
"Disease variant",
"Intellectual disability",
"Primary microcephaly"
] | [
"Cytosol"
] | [
"Centriolar satellite"
] | [] | [] | Approved | Enhanced | null | 49 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 48: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 62: Skeletal muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 3 | 2 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,311 | 9 |
ENSG00000075711 | DLG1 | Discs large MAGUK scaffold protein 1 | [
"Q12959"
] | 3 | 197042560-197299330 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016307",
"HPA069593"
] | [
"dJ1061C18.1.1",
"DLGH1",
"hdlg",
"SAP-97",
"SAP97"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [] | [] | [
"Vesicles"
] | [
"Plasma membrane",
"Basal body"
] | [] | [] | Approved | Supported | null | 75 | null | null | Cluster 24: Non-specific - Transcription | Cluster 11: White matter - Signal transduction | Cluster 72: Neuronal - Signal transduction | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,312 | 7 |
ENSG00000075785 | RAB7A | RAB7A, member RAS oncogene family | [
"P51149"
] | 3 | 128693669-128825942 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006964",
"CAB037131"
] | [
"CMT2B",
"RAB7"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Autophagy",
"Host-virus interaction",
"Lipid degradation",
"Lipid metabolism",
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Lysosomes",
"Primary cilium transition zone"
] | [
"Cytosol"
] | [] | [] | Approved | Supported | null | 209 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,313 | 9 |
ENSG00000075790 | BCAP29 | B cell receptor associated protein 29 | [
"Q9UHQ4"
] | 7 | 107580246-107629170 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029215",
"HPA049694"
] | [
"BAP29",
"DKFZp686M2086"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis",
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 11 | null | null | Cluster 32: Basophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 39: Non-specific - Transcription | Cluster 102: Non-specific - Mixed function | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,314 | 7 |
ENSG00000075826 | SEC31B | SEC31 homolog B, COPII coat complex component | [
"Q9NQW1"
] | 10 | 100486646-100519864 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035882",
"HPA040819",
"HPA060052"
] | [
"DKFZP434M183",
"SEC31B-1",
"SEC31L2"
] | [
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | null | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 71: Lymphoma - Inflammatory response | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,315 | 5 |
ENSG00000075856 | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein | [
"Q15020"
] | 12 | 108522214-108561400 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028840",
"HPA044322"
] | [
"KIAA0156",
"p110",
"RP11-13G14",
"TIP110"
] | [
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 119 | No | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 31: Non-specific - Transcription | Cluster 38: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 1,316 | 3 |
ENSG00000075884 | ARHGAP15 | Rho GTPase activating protein 15 | [
"Q53QZ3"
] | 2 | 143091362-143768352 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA032126"
] | [
"BM046"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | null | null | 2 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 71: Lymphoma - Inflammatory response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 51: Lymphoid tissue - Adaptive immune response | Group enriched | Detected in all | 5 | Group enriched | Detected in some | 6 | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | 1,317 | 9 |
ENSG00000075886 | TUBA3D | Tubulin alpha 3d | [
"P0DPH8"
] | 2 | 131476119-131482934 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004972",
"HPA039247",
"HPA043684",
"HPA063394"
] | [
"H2-ALPHA"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Microtubules"
] | [
"Primary cilium"
] | [] | [] | Enhanced | Uncertain | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 60: Prostate cancer - Unknown function | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 35: Non-specific - Mixed function | Group enriched | Detected in some | 16 | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,318 | 3 |
ENSG00000075891 | PAX2 | Paired box 2 | [
"Q02962"
] | 10 | 100735396-100829944 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013024",
"HPA047704",
"HPA070751"
] | [
"PAX-2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [
"Intracellular and membrane"
] | [
"Developmental protein"
] | Supported | Enhanced | null | 3 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 72: Kidney - Transmembrane transport | Group enriched | Detected in some | 6 | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,319 | 7 |
ENSG00000075914 | EXOSC7 | Exosome component 7 | [
"Q15024"
] | 3 | 44975241-45036066 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036182",
"HPA057980"
] | [
"EAP1",
"hRrp42p",
"KIAA0116",
"p8",
"RRP42",
"Rrp42p"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Approved | null | 61 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 8: Non-specific - Basic cellular processes | Cluster 55: Myocytes - Oxidative muscle function | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,320 | 4 |
ENSG00000075945 | KIFAP3 | Kinesin associated protein 3 | [
"Q92845"
] | 1 | 169921326-170085208 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023738",
"HPA023742"
] | [
"FLA3",
"KAP-1",
"KAP3",
"SMAP"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Microtubules",
"Basal body"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Supported | null | 39 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 5: Rhabdoid - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,321 | 3 |
ENSG00000075975 | MKRN2 | Makorin ring finger protein 2 | [
"Q9H000"
] | 3 | 12557057-12586208 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037559",
"HPA037560"
] | [
"HSPC070",
"RNF62"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 36 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,322 | 5 |
ENSG00000076003 | MCM6 | Minichromosome maintenance complex component 6 | [
"Q14566"
] | 2 | 135839626-135876443 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004818",
"CAB009577"
] | [
"Mis5"
] | [
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA replication"
] | [
"DNA-binding",
"Helicase",
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 101 | null | Yes | Cluster 9: T-regs - Cell cycle regulation | Cluster 35: Non-specific - DNA binding | Cluster 58: Non-specific - Nuclear processes | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,323 | 7 |
ENSG00000076043 | REXO2 | RNA exonuclease 2 | [
"Q9Y3B8"
] | 11 | 114439435-114450279 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038450",
"HPA038451"
] | [
"CGI-114",
"DKFZP566E144",
"SFN"
] | [
"Predicted intracellular proteins"
] | [] | [
"Exonuclease",
"Hydrolase",
"Nuclease"
] | [] | [
"Mitochondria"
] | [
"Nucleoli",
"Focal adhesion sites"
] | [] | [] | Supported | Enhanced | null | null | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 24: Non-specific - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,324 | 9 |
ENSG00000076053 | RBM7 | RNA binding motif protein 7 | [
"Q9Y580"
] | 11 | 114400030-114414203 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013993",
"HPA048003"
] | [] | [
"Predicted intracellular proteins"
] | [
"Meiosis"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 85 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,325 | 8 |
ENSG00000076067 | RBMS2 | RNA binding motif single stranded interacting protein 2 | [
"Q15434"
] | 12 | 56521820-56596193 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039225",
"HPA058784"
] | [
"SCR3"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Approved | null | 98 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,326 | 8 |
ENSG00000076108 | BAZ2A | Bromodomain adjacent to zinc finger domain 2A | [
"Q9UIF9"
] | 12 | 56595596-56636816 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005782",
"HPA063806"
] | [
"KIAA0314",
"TIP5",
"WALp3"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"DNA-binding",
"Repressor",
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Enhanced | null | null | 10 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 6: Non-specific - Immune response | Cluster 38: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,327 | 3 |
ENSG00000076201 | PTPN23 | Protein tyrosine phosphatase non-receptor type 23 | [
"Q9H3S7"
] | 3 | 47381011-47413435 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016845"
] | [
"DKFZP564F0923",
"HD-PTP",
"KIAA1471"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Protein transport",
"Transport"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm",
"Nuclear bodies",
"Basal body"
] | [
"Vesicles",
"Centriolar satellite",
"Cytosol",
"Calyx",
"Mid piece"
] | [] | [] | Supported | Approved | null | 44 | Yes | No | Cluster 32: Basophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 8: Non-specific - Basic cellular processes | Cluster 17: Non-specific - RNA processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,328 | 5 |
ENSG00000076242 | MLH1 | MutL homolog 1 | [
"P40692"
] | 3 | 36993350-37050846 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013294",
"HPA052707",
"HPA060714",
"CAB070868"
] | [
"COCA2",
"FCC2",
"HNPCC",
"HNPCC2",
"MLH-1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA damage",
"DNA repair"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Hereditary nonpolyposis colorectal cancer",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 138 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 8: Non-specific - Basic cellular processes | Cluster 7: Non-specific - Transcription | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,329 | 4 |
ENSG00000076248 | UNG | Uracil DNA glycosylase | [
"P13051"
] | 12 | 109097597-109126725 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011605",
"HPA071225"
] | [
"DGU",
"HIGM4",
"UDG",
"UNG1",
"UNG2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"DNA damage",
"DNA repair",
"Host-virus interaction"
] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Mitochondria"
] | [] | [] | Supported | Uncertain | null | 10 | null | Yes | Cluster 3: Non-specific - Nuclear processes | Cluster 44: Non-specific - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 1,330 | 2 |
ENSG00000076258 | FMO4 | Flavin containing dimethylaniline monoxygenase 4 | [
"P31512"
] | 1 | 171314183-171342084 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049100",
"HPA072438"
] | [
"FMO2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 14: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 51: Myeloma - Immunoglobulins | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 16: Liver & Kidney - Metabolism | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,331 | 7 |
ENSG00000076321 | KLHL20 | Kelch like family member 20 | [
"Q9Y2M5"
] | 1 | 173714941-173786692 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025034",
"HPA053704"
] | [
"KHLHX",
"KLEIP"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport",
"Ubl conjugation pathway"
] | [
"Actin-binding"
] | [] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 115 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 25: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,332 | 4 |
ENSG00000076344 | RGS11 | Regulator of G protein signaling 11 | [
"O94810"
] | 16 | 268301-275980 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041692",
"HPA043039"
] | [] | [
"Predicted intracellular proteins"
] | [] | [
"Signal transduction inhibitor"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 2 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,333 | 1 |
ENSG00000076351 | SLC46A1 | Solute carrier family 46 member 1 | [
"Q96NT5"
] | 17 | 28394642-28407197 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011614"
] | [
"HCP1",
"hPCFT",
"HsPCFT",
"MGC9564",
"PCFT"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Symport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 1 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 25: Non-specific - Transcription | Cluster 34: Testis cancer - Unknown function | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 7: Small intestine - Absorption and Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,334 | 4 |
ENSG00000076356 | PLXNA2 | Plexin A2 | [
"O75051"
] | 1 | 208022242-208244384 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB009763"
] | [
"FLJ11751",
"FLJ30634",
"KIAA0463",
"OCT",
"PLXN2"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 2 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,335 | 2 |
ENSG00000076382 | SPAG5 | Sperm associated antigen 5 | [
"Q96R06"
] | 17 | 28577565-28599025 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022008",
"HPA022479",
"HPA024418"
] | [
"DEEPEST",
"hMAP126",
"MAP126"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Nuclear bodies",
"Mitotic spindle"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 63 | Yes | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 32: Cerebral cortex - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Group enriched | Detected in many | 6 | 5 | 2 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,336 | 3 |
ENSG00000076513 | ANKRD13A | Ankyrin repeat domain 13A | [
"Q8IZ07"
] | 12 | 109999186-110039763 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039488",
"HPA043218"
] | [
"ANKRD13",
"NY-REN-25"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Vesicles",
"Primary cilium",
"Primary cilium tip",
"Primary cilium transition zone"
] | [] | [] | Supported | Enhanced | null | 41 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 46: Lymphoma - Humoral immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 34: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,337 | 3 |
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