ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000067560 | RHOA | Ras homolog family member A | [
"P61586"
] | 3 | 49359139-49412998 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005052"
] | [
"ARH12",
"ARHA",
"Rho12",
"RHOH12"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Cell cycle",
"Cell division",
"Host-virus interaction"
] | [
"Hydrolase"
] | [
"Cancer-related genes",
"Disease variant",
"Ectodermal dysplasia",
"Proto-oncogene"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 188 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 102: Non-specific - Mixed function | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,006 | 4 |
ENSG00000067596 | DHX8 | DEAH-box helicase 8 | [
"Q14562"
] | 17 | 43483865-43610338 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049285"
] | [
"DDX8",
"Dhr2",
"HRH1",
"PRP22",
"PRPF22"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Helicase",
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Approved | null | 69 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 32: Cerebral cortex - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,007 | 9 |
ENSG00000067646 | ZFY | Zinc finger protein Y-linked | [
"P08048"
] | Y | 2935281-2982506 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001748",
"HPA071863"
] | [
"ZNF911"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Approved | Uncertain | null | 5 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 16: Non-specific - Transcription | Cluster 47: Leukemia - Hemostasis | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 1,009 | 9 |
ENSG00000067704 | IARS2 | Isoleucyl-tRNA synthetase 2, mitochondrial | [
"Q9NSE4"
] | 1 | 220094132-220148041 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024212",
"HPA024594",
"HPA024596"
] | [
"FLJ10326"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase"
] | [
"Cataract",
"Deafness",
"Disease variant",
"Neuropathy"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 32 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 45: Non-specific - Nuclear processes | Cluster 17: Non-specific - RNA processing | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,010 | 3 |
ENSG00000067715 | SYT1 | Synaptotagmin 1 | [
"P21579"
] | 12 | 78863993-79452008 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008394",
"HPA064788"
] | [
"P65",
"SVP65",
"SYT"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Differentiation"
] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | Supported | 35 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in many | 10 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,011 | 5 |
ENSG00000067829 | IDH3G | Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma | [
"P51553"
] | X | 153785766-153794512 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000425",
"HPA002017"
] | [] | [
"Citric acid cycle related proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Tricarboxylic acid cycle"
] | [] | [] | [
"Nucleoli",
"Mitochondria"
] | [
"Plasma membrane"
] | [] | [] | Approved | Supported | null | 10 | Yes | No | Cluster 42: Non-specific - Vesicular transport | Cluster 14: Neurons - Synaptic function | Cluster 36: Non-specific - mRNA processing | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 1,013 | 8 |
ENSG00000067836 | ROGDI | Rogdi atypical leucine zipper | [
"Q9GZN7"
] | 16 | 4796968-4802880 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041000"
] | [
"FLJ22386",
"RAV2",
"ROGD1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Amelogenesis imperfecta",
"Epilepsy"
] | [] | [] | [] | [] | null | Uncertain | null | 9 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 51: Neurons - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 6 | 1 | 0 | 1 | [
"Kidney Chromophobe"
] | [] | [
"Kidney Chromophobe"
] | 1,014 | 9 |
ENSG00000067840 | PDZD4 | PDZ domain containing 4 | [
"Q76G19"
] | X | 153802166-153830565 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003878"
] | [
"FLJ34125",
"KIAA1444",
"LNX5",
"LU1",
"PDZK4",
"PDZRN4L"
] | [
"Cancer-related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 15: NK-cells - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in many | 6 | Cancer enriched | Detected in many | 4 | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,015 | 1 |
ENSG00000067842 | ATP2B3 | ATPase plasma membrane Ca2+ transporting 3 | [
"Q16720"
] | X | 153517642-153582939 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001583",
"HPA064779"
] | [
"CFAP39",
"CLA2",
"PMCA3",
"SCAX1"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calmodulin-binding",
"Translocase"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Neurodegeneration"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | Supported | 3 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,016 | 3 |
ENSG00000067900 | ROCK1 | Rho associated coiled-coil containing protein kinase 1 | [
"Q13464"
] | 18 | 20946906-21111813 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB004562",
"HPA007567",
"HPA045639"
] | [
"p160ROCK"
] | [
"Enzymes",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | 33 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 25: Non-specific - Transcription | Cluster 13: Non-specific - Mixed function | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,017 | 8 |
ENSG00000067955 | CBFB | Core-binding factor subunit beta | [
"Q13951"
] | 16 | 67028984-67101058 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038852",
"HPA058730"
] | [
"PEBP2B"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism",
"Proto-oncogene"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 20 | null | null | Cluster 32: Basophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 68: Non-specific - Cell cycle regulation | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 34: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,018 | 1 |
ENSG00000067992 | PDK3 | Pyruvate dehydrogenase kinase 3 | [
"Q15120"
] | X | 24465244-24550466 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046583",
"HPA072492"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Mitochondria"
] | [
"Nucleoli"
] | [] | [] | Supported | Approved | null | 27 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 14: Neurons - Synaptic function | Cluster 46: Lymphoma - Humoral immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,019 | 1 |
ENSG00000068001 | HYAL2 | Hyaluronidase 2 | [
"Q12891"
] | 3 | 50317790-50322782 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036436"
] | [
"LuCa-2",
"LUCA2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosidase",
"Hydrolase",
"Receptor"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Uncertain | null | 43 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,020 | 4 |
ENSG00000068024 | HDAC4 | Histone deacetylase 4 | [
"P56524"
] | 2 | 239048168-239401654 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048723",
"HPA071448"
] | [
"BDMR",
"HA6116",
"HD4",
"HDAC-4",
"HDAC-A",
"HDACA",
"KIAA0288"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Hydrolase",
"Repressor"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets",
"Intellectual disability"
] | [
"Nuclear speckles"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Approved | null | 89 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 32: Cerebral cortex - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,021 | 2 |
ENSG00000068028 | RASSF1 | Ras association domain family member 1 | [
"Q9NS23"
] | 3 | 50329782-50340980 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040735"
] | [
"123F2",
"NORE2A",
"RDA32",
"REH3P21"
] | [
"Human disease related genes",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Cell cycle"
] | [] | [
"Tumor suppressor"
] | [] | [] | [] | [] | null | Approved | null | 52 | null | Yes | Cluster 32: Basophils - Transcription | Cluster 6: Non-specific - Immune response | Cluster 8: Non-specific - Basic cellular processes | Cluster 103: Non-specific - Basic cellular processes | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,022 | 1 |
ENSG00000068078 | FGFR3 | Fibroblast growth factor receptor 3 | [
"P22607"
] | 4 | 1793293-1808872 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004231",
"HPA067204"
] | [
"ACH",
"CD333",
"CEK2",
"JTK4"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [
"Apoptosis"
] | [
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes",
"Craniosynostosis",
"Deafness",
"Disease variant",
"Dwarfism",
"Ectodermal dysplasia",
"FDA approved drug targets",
"Lacrimo-auriculo-dento-digital syndrome"
] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted - unknown location"
] | [
"Receptor"
] | Supported | Enhanced | null | 218 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,023 | 9 |
ENSG00000068079 | IFI35 | Interferon induced protein 35 | [
"P80217"
] | 17 | 43006740-43014456 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003283",
"HPA045946",
"HPA075580"
] | [
"IFP35"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Immunity",
"Innate immunity"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nucleoli"
] | [
"Secreted to blood"
] | [
"Immunity"
] | Supported | Approved | null | 7 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 43: Hindbrain - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,024 | 8 |
ENSG00000068097 | HEATR6 | HEAT repeat containing 6 | [
"Q6AI08"
] | 17 | 60041008-60078922 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030789",
"HPA062157"
] | [
"ABC1",
"FLJ22087"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | 21 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 27: Breast cancer - Unknown function | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,025 | 2 |
ENSG00000068305 | MEF2A | Myocyte enhancer factor 2A | [
"Q02078"
] | 15 | 99565417-99716488 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004499",
"HPA046597",
"HPA056563"
] | [
"RSRFC4",
"RSRFC9"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Apoptosis",
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 19 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 6: Leukemia - Signal transduction | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,028 | 8 |
ENSG00000068308 | OTUD5 | OTU deubiquitinase 5 | [
"Q96G74"
] | X | 48922024-48958386 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017375"
] | [
"DKFZp761A052",
"DUBA"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [] | [] | Approved | Approved | null | 14 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 1: Neurons - Mixed function | Cluster 20: Myeloma - Immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 1,029 | 7 |
ENSG00000068323 | TFE3 | Transcription factor binding to IGHM enhancer 3 | [
"P19532"
] | X | 49028726-49043410 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023881"
] | [
"bHLHe33",
"TFEA"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Adaptive immunity",
"Immunity",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability",
"Proto-oncogene"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 44: Non-specific - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,030 | 9 |
ENSG00000068354 | TBC1D25 | TBC1 domain family member 25 | [
"Q3MII6"
] | X | 48539714-48562609 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029197"
] | [
"OATL1"
] | [
"Predicted intracellular proteins"
] | [
"Autophagy"
] | [
"GTPase activation"
] | [] | [] | [] | [] | [] | null | Approved | Approved | 19 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,031 | 1 |
ENSG00000068366 | ACSL4 | Acyl-CoA synthetase long chain family member 4 | [
"O60488"
] | X | 109624244-109733403 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000286",
"HPA005552"
] | [
"ACS4",
"FACL4",
"LACS4",
"MRX63",
"MRX68"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Ligase"
] | [
"Alport syndrome",
"Deafness",
"Disease variant",
"Elliptocytosis",
"Hereditary hemolytic anemia",
"Intellectual disability"
] | [
"Golgi apparatus"
] | [
"Mitochondria"
] | [] | [] | Approved | Supported | null | 11 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,032 | 7 |
ENSG00000068383 | INPP5A | Inositol polyphosphate-5-phosphatase A | [
"Q14642"
] | 10 | 132537787-132783480 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012285"
] | [
"5PTASE"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 15: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Immune cell enriched | Detected in single | 8 | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,033 | 8 |
ENSG00000068394 | GPKOW | G-patch domain and KOW motifs | [
"Q92917"
] | X | 49113407-49123735 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000287",
"HPA001894"
] | [
"GPATC5",
"GPATCH5",
"Mos2",
"Spp2",
"T54"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 69 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 19: Astrocytes - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,034 | 8 |
ENSG00000068400 | GRIPAP1 | GRIP1 associated protein 1 | [
"Q4V328"
] | X | 48973720-49002265 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000282",
"HPA000615"
] | [
"DKFZp434P0630",
"GRASP-1",
"GRASP1",
"KIAA1167",
"MPMGp800B12492Q3"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 62 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 1: Neurons - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,035 | 8 |
ENSG00000068438 | FTSJ1 | FtsJ RNA 2'-O-methyltransferase 1 | [
"Q9UET6"
] | X | 48476021-48486364 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002718"
] | [
"CDLIV",
"JM23",
"MRX44",
"MRX9",
"SPB1",
"TRM7",
"TRMT7"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Methyltransferase",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 5 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 14: Neurons - Synaptic function | Cluster 36: Non-specific - mRNA processing | Cluster 8: Non-specific - Secretory pathway | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,036 | 8 |
ENSG00000068489 | PRR11 | Proline rich 11 | [
"Q96HE9"
] | 17 | 59155732-59206709 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023923",
"HPA052376"
] | [
"FLJ11029"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Uncertain | null | 4 | Yes | Yes | Cluster 25: Non-specific - Unknown function | Cluster 48: Non-specific - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 5 | 2 | 4 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,037 | 4 |
ENSG00000068615 | REEP1 | Receptor accessory protein 1 | [
"Q9H902"
] | 2 | 86213993-86338083 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058061"
] | [
"C2orf23",
"FLJ13110",
"SPG31",
"Yip2a"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration",
"Neuropathy"
] | [] | [] | [] | [] | null | Enhanced | null | 19 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 74: Non-specific - Signal transduction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,038 | 2 |
ENSG00000068650 | ATP11A | ATPase phospholipid transporting 11A | [
"P98196"
] | 13 | 112690038-112887168 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035583",
"HPA035584"
] | [
"ATPIH",
"ATPIS",
"KIAA1021"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [
"Deafness",
"Disease variant",
"Leukodystrophy",
"Neuropathy",
"Non-syndromic deafness"
] | [
"Vesicles"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Approved | null | 8 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 7: Liver cancer - Metabolism | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,039 | 4 |
ENSG00000068697 | LAPTM4A | Lysosomal protein transmembrane 4 alpha | [
"Q15012"
] | 2 | 20032650-20051628 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031402",
"HPA031404",
"HPA068554"
] | [
"HUMORF13",
"KIAA0108",
"LAPTM4",
"MBNT",
"Mtrp"
] | [
"Predicted membrane proteins"
] | [
"Transport"
] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,041 | 9 |
ENSG00000068724 | TTC7A | Tetratricopeptide repeat domain 7A | [
"Q9ULT0"
] | 2 | 46915869-47076137 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036781",
"HPA036782"
] | [
"KIAA1140",
"TTC7"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 8: Immune cells - Immune response | Cluster 6: Leukemia - Signal transduction | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,042 | 5 |
ENSG00000068781 | STON1-GTF2A1L | STON1-GTF2A1L readthrough | [] | 2 | 48529925-48776517 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA005715",
"HPA074358"
] | [
"SALF"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 57: Podocytes - Glomerular filtration | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in some | null | Cancer enriched | Detected in single | 18 | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,044 | 9 |
ENSG00000068784 | SRBD1 | S1 RNA binding domain 1 | [
"Q8N5C6"
] | 2 | 45388680-45612165 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030567",
"HPA030568"
] | [
"FLJ10379"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 8 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,045 | 8 |
ENSG00000068796 | KIF2A | Kinesin family member 2A | [
"O00139"
] | 5 | 62306162-62391025 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004715",
"HPA004716"
] | [
"HK2",
"KIF2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Differentiation",
"Mitosis",
"Neurogenesis"
] | [
"Developmental protein",
"Motor protein"
] | [
"Cancer-related genes",
"Disease variant",
"Lissencephaly"
] | [
"Nucleoplasm",
"Nucleoli",
"Centrosome",
"Basal body",
"Annulus"
] | [
"Mitotic spindle",
"Cytosol",
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Approved | null | 42 | Yes | No | Cluster 1: T-cells - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 47: Platelets - Hemostasis | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,046 | 8 |
ENSG00000068831 | RASGRP2 | RAS guanyl releasing protein 2 | [
"Q7LDG7"
] | 11 | 64726911-64745456 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015635",
"HPA015667"
] | [
"CALDAG-GEFI"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Approved | null | null | null | null | Cluster 29: Non-specific - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 47: Platelets - Hemostasis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Group enriched | Detected in many | 9 | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 6 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,047 | 7 |
ENSG00000068878 | PSME4 | Proteasome activator subunit 4 | [
"Q14997"
] | 2 | 53864069-53970993 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA060922"
] | [
"KIAA0077",
"PA200"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"DNA damage",
"DNA repair",
"Spermatogenesis"
] | [
"Developmental protein"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 95 | null | null | Cluster 32: Basophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,048 | 4 |
ENSG00000068885 | IFT80 | Intraflagellar transport 80 | [
"Q9P2H3"
] | 3 | 160256986-160399880 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035868"
] | [
"FAP167",
"KIAA1374",
"WDR56"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Disease variant"
] | [] | [] | [] | [] | null | Uncertain | null | 44 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 11: White matter - Signal transduction | Cluster 63: Non-specific - Protein processing | Cluster 80: Oligodendrocytes - Myelination | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,049 | 3 |
ENSG00000068903 | SIRT2 | Sirtuin 2 | [
"Q8IXJ6"
] | 19 | 38878555-38899862 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004573",
"HPA011165"
] | [
"SIR2L"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Autophagy",
"Cell cycle",
"Cell division",
"Differentiation",
"Immunity",
"Innate immunity",
"Meiosis",
"Mitosis",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Transferase"
] | [
"Cancer-related genes",
"Neurodegeneration"
] | [
"Nucleoli",
"Cytosol"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 30: White matter - Myelination | Cluster 4: Non-specific - Transcription | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 25: Non-specific - Basic cellular processes | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,050 | 9 |
ENSG00000068912 | ERLEC1 | Endoplasmic reticulum lectin 1 | [
"Q96DZ1"
] | 2 | 53787009-53833038 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031501",
"HPA031502",
"HPA031503"
] | [
"C2orf30",
"CL25084",
"ERLECTIN",
"XTP3-B",
"XTP3TPB"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | null | Enhanced | null | 52 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 23: Choroid plexus - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,051 | 3 |
ENSG00000068971 | PPP2R5B | Protein phosphatase 2 regulatory subunit B'beta | [
"Q15173"
] | 11 | 64917553-64934475 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036607"
] | [
"B56B",
"B56beta",
"FLJ35411",
"PR61B"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 12 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 24: Non-specific - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Immune cell enriched | Detected in some | 7 | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,052 | 4 |
ENSG00000068976 | PYGM | Glycogen phosphorylase, muscle associated | [
"P11217"
] | 11 | 64746389-64759974 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056003"
] | [
"GSD5"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Glycogen metabolism"
] | [
"Allosteric enzyme",
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant",
"Glycogen storage disease"
] | [] | [] | [] | [] | null | Enhanced | null | 30 | null | null | Cluster 32: Basophils - Transcription | Cluster 19: Astrocytes - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in many | 65 | Cancer enriched | Detected in some | 10 | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Immune cell enriched | Detected in some | 6 | 0 | 0 | 0 | [] | [] | [] | 1,053 | 9 |
ENSG00000068985 | PAGE1 | PAGE family member 1 | [
"O75459"
] | X | 49687447-49695984 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003473"
] | [
"CT16.3",
"GAGE-9",
"GAGEB1",
"PAGE-1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | Approved | Enhanced | null | 14 | null | null | null | null | Cluster 51: Myeloma - Immunoglobulins | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in single | 159 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,054 | 5 |
ENSG00000069011 | PITX1 | Paired like homeodomain 1 | [
"P78337"
] | 5 | 135027734-135034813 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008743"
] | [
"BFT",
"POTX",
"PTX1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Disease variant"
] | [
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 70 | Yes | No | null | Cluster 36: Choroid plexus - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,055 | 5 |
ENSG00000069018 | TRPC7 | Transient receptor potential cation channel subfamily C member 7 | [
"Q9HCX4"
] | 5 | 136212745-136365545 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB022592",
"HPA031126"
] | [] | [
"Predicted membrane proteins",
"Voltage-gated ion channels"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 10: Ciliated cells - Ion channel activity | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,056 | 7 |
ENSG00000069020 | MAST4 | Microtubule associated serine/threonine kinase family member 4 | [
"O15021"
] | 5 | 66596380-67169593 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000544"
] | [
"KIAA0303"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 31: T-cells - T-cell receptor | Cluster 53: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 4 | 0 | 4 | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,057 | 5 |
ENSG00000069122 | ADGRF5 | Adhesion G protein-coupled receptor F5 | [
"Q8IZF2"
] | 6 | 46852522-46954943 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"DKFZp564O1923",
"GPR116",
"KIAA0758"
] | [
"G-protein coupled receptors",
"Plasma proteins",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,058 | 4 |
ENSG00000069188 | SDK2 | Sidekick cell adhesion molecule 2 | [
"Q58EX2"
] | 17 | 73334384-73644445 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FLJ10832",
"KIAA1514"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 49: Hindbrain - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,059 | 3 |
ENSG00000069206 | ADAM7 | ADAM metallopeptidase domain 7 | [
"Q9H2U9"
] | 8 | 24440930-24526970 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008879"
] | [
"EAPI",
"GP-83"
] | [
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | null | Enhanced | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 60: Prostate cancer - Unknown function | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 50: Epididymis - Male reproductive secretion | Tissue enriched | Detected in some | 237 | Cancer enriched | Detected in single | 22 | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 1,060 | 1 |
ENSG00000069248 | NUP133 | Nucleoporin 133 | [
"Q8WUM0"
] | 1 | 229440259-229508341 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059767"
] | [
"FLJ10814"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA transport",
"Protein transport",
"Translocation",
"Transport"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nuclear membrane"
] | [] | [] | [] | Supported | Approved | null | 63 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 55: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 1,061 | 3 |
ENSG00000069275 | NUCKS1 | Nuclear casein kinase and cyclin dependent kinase substrate 1 | [
"Q9H1E3"
] | 1 | 205712822-205750182 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062351",
"HPA063843"
] | [
"NUCKS"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Supported | Supported | null | 118 | No | No | Cluster 3: Non-specific - Nuclear processes | Cluster 13: Oligodendrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,062 | 8 |
ENSG00000069329 | VPS35 | VPS35 retromer complex component | [
"Q96QK1"
] | 16 | 46656132-46689518 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040802"
] | [
"FLJ10752",
"MEM3",
"PARK17"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction",
"Protein transport",
"Transport"
] | [] | [
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [
"Endosomes",
"Lysosomes"
] | [] | [] | [] | Approved | Supported | null | 105 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 9: Non-specific - Receptor signaling | Cluster 6: Leukemia - Signal transduction | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,063 | 1 |
ENSG00000069345 | DNAJA2 | DnaJ heat shock protein family (Hsp40) member A2 | [
"O60884"
] | 16 | 46955362-46973674 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049789",
"HPA060538"
] | [
"CPR3",
"DNAJ",
"DNJ3",
"HIRIP4"
] | [
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Nucleoli",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 118 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 31: Non-specific - Transcription | Cluster 68: Non-specific - Cell cycle regulation | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,064 | 5 |
ENSG00000069399 | BCL3 | BCL3 transcription coactivator | [
"P20749"
] | 19 | 44747705-44760044 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002051",
"HPA047514"
] | [
"BCL4",
"D19S37"
] | [
"Cancer-related genes",
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Midbody",
"Primary cilium",
"Basal body",
"Cytosol"
] | [] | [] | Supported | Approved | null | 25 | Yes | No | Cluster 21: Neutrophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 15: Kidney cancer - Membrane components | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,065 | 6 |
ENSG00000069431 | ABCC9 | ATP binding cassette subfamily C member 9 | [
"O60706"
] | 12 | 21797389-21942543 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007279"
] | [
"CMD1O",
"SUR2"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [
"Receptor"
] | [
"Atrial fibrillation",
"Cardiomyopathy",
"Disease variant",
"FDA approved drug targets",
"Intellectual disability"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 110: Mural cells - ECM organization | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,067 | 6 |
ENSG00000069482 | GAL | Galanin and GMAP prepropeptide | [
"P22466"
] | 11 | 68683779-68691175 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049864",
"CAB079779"
] | [
"GAL-GMAP",
"GALN",
"GLNN",
"GMAP"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone",
"Neuropeptide"
] | [
"Disease variant",
"Epilepsy"
] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [
"Secreted to blood"
] | [
"Hormone"
] | Approved | Enhanced | Supported | 13 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 20: Pituitary gland - Hormone signaling | Tissue enriched | Detected in many | 9 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 1,068 | 1 |
ENSG00000069493 | CLEC2D | C-type lectin domain family 2 member D | [
"Q9UHP7"
] | 12 | 9664969-9699553 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017649",
"HPA047584"
] | [
"CLAX",
"LLT1",
"OCIL"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Uncertain | Uncertain | null | 2 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 6: Non-specific - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 10 | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,069 | 8 |
ENSG00000069509 | FUNDC1 | FUN14 domain containing 1 | [
"Q8IVP5"
] | X | 44523639-44542859 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038773"
] | [
"MGC51029"
] | [
"Predicted intracellular proteins"
] | [
"Autophagy"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 20 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 45: Non-specific - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 97: Non-specific - Cellular respiration | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,070 | 7 |
ENSG00000069535 | MAOB | Monoamine oxidase B | [
"P27338"
] | X | 43766610-43882450 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002328",
"CAB037200"
] | [] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Oxidoreductase"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 30 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,071 | 7 |
ENSG00000069667 | RORA | RAR related orphan receptor A | [
"P35398"
] | 15 | 60488284-61229302 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009861",
"HPA074448"
] | [
"NR1F1",
"ROR1",
"ROR2",
"ROR3",
"RZRA"
] | [
"Disease related genes",
"Human disease related genes",
"Nuclear receptors",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding",
"Receptor"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 13 | null | null | Cluster 1: T-cells - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 20: Myeloma - Immune response | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 37: Skin - Keratinization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,072 | 3 |
ENSG00000069696 | DRD4 | Dopamine receptor D4 | [
"P21917"
] | 11 | 637269-640706 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA062682"
] | [] | [
"FDA approved drug targets",
"G-protein coupled receptors",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Biological rhythms"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Centrosome"
] | [] | [] | Uncertain | null | null | 10 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 37: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Not detected | Not detected | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,073 | 2 |
ENSG00000069764 | PLA2G10 | Phospholipase A2 group X | [
"O15496"
] | 16 | 14672548-14694308 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041893"
] | [
"GXPLA2"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [
"Lipid metabolism",
"Phospholipid metabolism"
] | [
"Hydrolase"
] | [
"FDA approved drug targets"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | null | Uncertain | null | 42 | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,075 | 1 |
ENSG00000069812 | HES2 | Hes family bHLH transcription factor 2 | [
"Q9Y543"
] | 1 | 6412418-6424670 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA039462"
] | [
"bHLHb40"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func. | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 8 | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 1,076 | 4 |
ENSG00000069849 | ATP1B3 | ATPase Na+/K+ transporting subunit beta 3 | [
"P54709"
] | 3 | 141876124-141926549 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020697",
"HPA048963"
] | [
"CD298",
"FLJ29027"
] | [
"CD markers",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Sodium/potassium transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 39 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 44: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 103: Non-specific - Basic cellular processes | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 1,077 | 2 |
ENSG00000069869 | NEDD4 | NEDD4 E3 ubiquitin protein ligase | [
"P46934"
] | 15 | 55826922-55993660 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001991",
"HPA039883",
"HPA046793",
"CAB072833"
] | [
"KIAA0093",
"MGC176705",
"NEDD4-1",
"RPF1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction",
"Neurogenesis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 214 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,078 | 6 |
ENSG00000069943 | PIGB | Phosphatidylinositol glycan anchor biosynthesis class B | [
"Q92521"
] | 15 | 55318960-55355648 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039929"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"GPI-anchor biosynthesis"
] | [
"Glycosyltransferase",
"Transferase"
] | [
"Epilepsy"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Uncertain | Uncertain | null | null | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 58: Non-specific - Nuclear processes | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,079 | 2 |
ENSG00000069956 | MAPK6 | Mitogen-activated protein kinase 6 | [
"Q16659"
] | 15 | 51952106-52067375 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005184",
"HPA030262",
"HPA047825"
] | [
"ERK3",
"HsT17250",
"p97MAPK",
"PRKM6"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Cytosol"
] | [
"Microtubules",
"Primary cilium"
] | [] | [] | Approved | Approved | Supported | 37 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 1,080 | 6 |
ENSG00000069966 | GNB5 | G protein subunit beta 5 | [
"O14775"
] | 15 | 52115100-52191392 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041942",
"HPA044198"
] | [
"GB5"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Transducer"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nuclear speckles"
] | [
"Centrosome",
"Rods & Rings"
] | [] | [] | Approved | Uncertain | null | 19 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 58: Non-specific - Nuclear processes | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,081 | 8 |
ENSG00000069974 | RAB27A | RAB27A, member RAS oncogene family | [
"P51159"
] | 15 | 55202966-55319113 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001333",
"CAB034046"
] | [
"GS2",
"HsT18676",
"RAB27",
"RAM"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Exocytosis"
] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Mid piece",
"Principal piece"
] | [] | [] | [] | Approved | Enhanced | null | 30 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 44: Non-specific - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Rectum Adenocarcinoma"
] | 1,082 | 4 |
ENSG00000069998 | HDHD5 | Haloacid dehalogenase like hydrolase domain containing 5 | [
"Q9BXW7"
] | 22 | 17137511-17165287 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005548",
"HPA076973"
] | [
"CECR5"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Approved | null | 2 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 27: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,083 | 8 |
ENSG00000070010 | UFD1 | Ubiquitin recognition factor in ER associated degradation 1 | [
"Q92890"
] | 22 | 19449911-19479202 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030286",
"HPA030287"
] | [
"UFD1L"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 30 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,084 | 9 |
ENSG00000070018 | LRP6 | LDL receptor related protein 6 | [
"O75581"
] | 12 | 12116025-12267044 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004490",
"HPA029925"
] | [
"ADCAD2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Endocytosis",
"Wnt signaling pathway"
] | [
"Developmental protein",
"Receptor"
] | [
"Cancer-related genes",
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 66 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 102: Non-specific - Mixed function | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Cancer enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,085 | 5 |
ENSG00000070031 | SCT | Secretin | [
"P09683"
] | 11 | 626309-627181 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050961"
] | [] | [
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | Enhanced | null | 2 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 6: Non-specific - Immune response | Cluster 10: Ciliated cells - Ion channel activity | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in some | 4 | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 11 | Immune cell enriched | Detected in single | 137 | 1 | 0 | 1 | [] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | 1,087 | 7 |
ENSG00000070047 | PHRF1 | PHD and ring finger domains 1 | [
"Q9P1Y6"
] | 11 | 576470-612222 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019867",
"HPA062933"
] | [
"KIAA1542",
"PPP1R125",
"RNF221"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 9 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 6: Non-specific - Immune response | Cluster 40: Non-specific - Unknown function | Cluster 102: Non-specific - Mixed function | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 1,088 | 1 |
ENSG00000070061 | ELP1 | Elongator acetyltransferase complex subunit 1 | [
"O95163"
] | 9 | 108866898-108934328 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB021340",
"HPA049677",
"HPA050686"
] | [
"DYS",
"IKAP",
"IKBKAP",
"IKI3",
"TOT1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [] | [
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 39 | null | null | Cluster 32: Basophils - Transcription | Cluster 44: Non-specific - Mixed function | Cluster 43: Non-specific - Basic cellular processes | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in many | 8 | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,089 | 7 |
ENSG00000070081 | NUCB2 | Nucleobindin 2 | [
"P80303"
] | 11 | 17208153-17349980 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008395",
"CAB015931",
"CAB079781"
] | [
"NEFA"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"DNA-binding",
"Guanine-nucleotide releasing factor"
] | [
"Cancer-related genes"
] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Other"
] | Enhanced | Enhanced | Supported | 13 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 36: Choroid plexus - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 8: Non-specific - Secretory pathway | Cluster 38: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,090 | 6 |
ENSG00000070087 | PFN2 | Profilin 2 | [
"P35080"
] | 3 | 149964904-150050788 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035611",
"CAB037073"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Actin-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 25 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 51: Neurons - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 1,091 | 1 |
ENSG00000070159 | PTPN3 | Protein tyrosine phosphatase non-receptor type 3 | [
"P26045"
] | 9 | 109375466-109498313 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038343",
"HPA046728"
] | [
"PTPH1"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [] | [] | [] | [] | null | Approved | null | 61 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,092 | 4 |
ENSG00000070182 | SPTB | Spectrin beta, erythrocytic | [
"P11277"
] | 14 | 64746283-64879907 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003394",
"HPA003398",
"CAB015169",
"CAB016232"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin capping",
"Actin-binding"
] | [
"Disease variant",
"Elliptocytosis",
"Hereditary hemolytic anemia"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 9 | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 1,093 | 9 |
ENSG00000070190 | DAPP1 | Dual adaptor of phosphotyrosine and 3-phosphoinositides 1 | [
"Q9UN19"
] | 4 | 99816827-99870190 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB033822",
"HPA046074"
] | [
"BAM32"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 13 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 1,094 | 7 |
ENSG00000070193 | FGF10 | Fibroblast growth factor 10 | [
"O15520"
] | 5 | 44300247-44389706 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB010315"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Growth factor"
] | [
"Disease variant",
"Ectodermal dysplasia",
"Lacrimo-auriculo-dento-digital syndrome"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Growth factor"
] | null | Uncertain | null | 6 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 5: Rhabdoid - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Group enriched | Detected in some | 5 | Cancer enriched | Detected in some | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,095 | 5 |
ENSG00000070214 | SLC44A1 | Solute carrier family 44 member 1 | [
"Q8WWI5"
] | 9 | 105244622-105439171 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064714",
"HPA074007"
] | [
"CD92",
"CDW92",
"CHTL1",
"CTL1"
] | [
"CD markers",
"Disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Transport"
] | [] | [
"Neurodegeneration"
] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 44: Connective tissue cells - ECM organization | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 4 | Immune cell enhanced | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,096 | 4 |
ENSG00000070269 | TMEM260 | Transmembrane protein 260 | [
"Q9NX78"
] | 14 | 56488354-56650606 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003502"
] | [
"C14orf101",
"FLJ20392"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Uncertain | null | 2 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 50: Non-specific - Nucleic acid binding | Cluster 71: Lymphoma - Inflammatory response | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,097 | 8 |
ENSG00000070366 | SMG6 | SMG6 nonsense mediated mRNA decay factor | [
"Q86US8"
] | 17 | 2059839-2303785 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042932"
] | [
"C17orf31",
"EST1A",
"KIAA0732",
"SMG-6"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Nonsense-mediated mRNA decay"
] | [
"DNA-binding",
"Endonuclease",
"Hydrolase",
"Nuclease"
] | [] | [
"Nucleoli"
] | [
"Golgi apparatus",
"Plasma membrane",
"Primary cilium tip",
"Basal body",
"Cytosol"
] | [] | [] | Supported | Approved | null | 13 | null | null | Cluster 1: T-cells - Unknown function | Cluster 46: Brainstem - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,098 | 5 |
ENSG00000070371 | CLTCL1 | Clathrin heavy chain like 1 | [
"P53675"
] | 22 | 19179473-19291719 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA075327",
"HPA075795"
] | [
"CHC22",
"CLH22",
"CLTCL",
"CLTD"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 13 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 45: Non-specific - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 8 | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,100 | 8 |
ENSG00000070388 | FGF22 | Fibroblast growth factor 22 | [
"Q9HCT0"
] | 19 | 639879-644373 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Growth factor"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Growth factor"
] | null | null | null | null | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,101 | 7 |
ENSG00000070404 | FSTL3 | Follistatin like 3 | [
"O95633"
] | 19 | 676392-683392 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB024899",
"HPA045378"
] | [
"FLRG",
"FSRP"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Osteogenesis",
"Transcription",
"Transcription regulation"
] | [] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [
"Secreted in other tissues"
] | [
"Transcription"
] | Supported | Approved | null | 1 | null | Yes | Cluster 2: Dendritic cells - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Low immune cell specificity | Detected in some | null | 4 | 0 | 4 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,102 | 8 |
ENSG00000070413 | DGCR2 | DiGeorge syndrome critical region gene 2 | [
"P98153"
] | 22 | 19036282-19122454 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000873"
] | [
"DGS-C",
"IDD",
"KIAA0163",
"LAN",
"SEZ-12"
] | [
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [
"Receptor"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 27 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 32: Cerebral cortex - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 2: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,103 | 6 |
ENSG00000070423 | RNF126 | Ring finger protein 126 | [
"Q9BV68"
] | 19 | 647526-663233 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043050"
] | [
"FLJ20552"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 38 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 23: Non-specific - Transcription | Cluster 26: Keratinocytes - Keratinization | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,104 | 4 |
ENSG00000070444 | MNT | MAX network transcriptional repressor | [
"Q99583"
] | 17 | 2384073-2401104 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059532",
"HPA067578"
] | [
"bHLHd3",
"lncRNA-HAL",
"MAD6",
"MXD6",
"ROX"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | 8 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 1,105 | 9 |
ENSG00000070476 | ZXDC | ZXD family zinc finger C | [
"Q2QGD7"
] | 3 | 126437601-126475891 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049593"
] | [
"FLJ13861",
"MGC11349"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoli"
] | [] | [] | [] | Approved | null | null | 24 | Yes | No | Cluster 7: Non-specific - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 63: Non-specific - Protein processing | Cluster 55: Myocytes - Oxidative muscle function | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,106 | 7 |
ENSG00000070495 | JMJD6 | Jumonji domain containing 6, arginine demethylase and lysine hydroxylase | [
"Q6NYC1"
] | 17 | 76712832-76726799 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004548",
"HPA059156",
"HPA074031"
] | [
"KIAA0585",
"PTDSR",
"PTDSR1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Developmental protein",
"Dioxygenase",
"Oxidoreductase",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 63 | No | No | Cluster 25: Non-specific - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,107 | 9 |
ENSG00000070501 | POLB | DNA polymerase beta | [
"P06746"
] | 8 | 42338454-42371808 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011616",
"HPA049104",
"HPA069013",
"CAB080371"
] | [] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"DNA replication",
"DNA synthesis"
] | [
"DNA-binding",
"DNA-directed DNA polymerase",
"Lyase",
"Nucleotidyltransferase",
"Transferase"
] | [
"FDA approved drug targets"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 32 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 35: Non-specific - DNA binding | Cluster 29: Non-specific - Unknown function | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,108 | 8 |
ENSG00000070526 | ST6GALNAC1 | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 | [
"Q9NSC7"
] | 17 | 76624761-76643786 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014767",
"HPA014975"
] | [
"SIAT7A",
"ST6GalNAcI"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant"
] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 31: T-cells - T-cell receptor | Cluster 47: Endothelial cells - Vasculature | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,109 | 4 |
ENSG00000070540 | WIPI1 | WD repeat domain, phosphoinositide interacting 1 | [
"Q5MNZ9"
] | 17 | 68420948-68457513 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007493",
"CAB037230"
] | [
"ATG18",
"ATG18A",
"FLJ10055",
"WIPI49"
] | [
"Predicted intracellular proteins"
] | [
"Autophagy"
] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | null | null | null | Cluster 22: Eosinophils - Transcription | Cluster 42: Choroid plexus - Mitochondria | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in many | 4 | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,110 | 4 |
ENSG00000070601 | FRMPD1 | FERM and PDZ domain containing 1 | [
"Q5SYB0"
] | 9 | 37650954-37746904 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042934"
] | [
"FRMD2",
"KIAA0967"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 38: Sub-cortical - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in many | 7 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 8 | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,111 | 2 |
ENSG00000070610 | GBA2 | Glucosylceramidase beta 2 | [
"Q9HCG7"
] | 9 | 35736866-35749228 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024026"
] | [
"AD035",
"DKFZp762K054",
"KIAA1605",
"SPG46"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Sphingolipid metabolism",
"Steroid metabolism",
"Sterol metabolism"
] | [
"Glycosidase",
"Glycosyltransferase",
"Hydrolase",
"Transferase"
] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [
"Nucleoplasm",
"Golgi apparatus"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 23: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,112 | 6 |
ENSG00000070614 | NDST1 | N-deacetylase and N-sulfotransferase 1 | [
"P52848"
] | 5 | 150485818-150558211 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA060532"
] | [
"HSST",
"NST1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Inflammatory response"
] | [
"Hydrolase",
"Multifunctional enzyme",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 27: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 8 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,113 | 2 |
ENSG00000070669 | ASNS | Asparagine synthetase (glutamine-hydrolyzing) | [
"P08243"
] | 7 | 97851677-97872542 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004924",
"HPA029318",
"HPA064737"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Amino-acid biosynthesis",
"Asparagine biosynthesis"
] | [
"Ligase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 14 | No | No | Cluster 43: Non-specific - Transcription & Translation | Cluster 37: Neurons - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,114 | 9 |
ENSG00000070718 | AP3M2 | Adaptor related protein complex 3 subunit mu 2 | [
"P53677"
] | 8 | 42152946-42171673 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB014876",
"HPA045591",
"HPA048380"
] | [
"AP47B",
"CLA20"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 4 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 40: Non-specific - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,115 | 4 |
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