ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000079308 | TNS1 | Tensin 1 | [
"Q9HBL0"
] | 2 | 217799588-218033982 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018774",
"HPA036089",
"HPA036090"
] | [
"DKFZp586K0617",
"MXRA6",
"PPP1R155",
"TNS"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Focal adhesion sites"
] | [] | [] | [] | Enhanced | Approved | null | 2 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 47: Endothelial cells - Vasculature | Cluster 47: Leukemia - Hemostasis | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 6 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,447 | 1 |
ENSG00000079313 | REXO1 | RNA exonuclease 1 homolog | [
"Q8N1G1"
] | 19 | 1815248-1848483 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042155",
"HPA042552"
] | [
"EloA-BP1",
"KIAA1138",
"TCEB3BP1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Exonuclease",
"Hydrolase",
"Nuclease"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Approved | null | 2 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 1,448 | 9 |
ENSG00000079332 | SAR1A | Secretion associated Ras related GTPase 1A | [
"Q9NR31"
] | 10 | 70147289-70170523 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006923",
"CAB022545",
"HPA048368"
] | [
"SAR1",
"Sara",
"SARA1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Supported | null | 74 | null | null | Cluster 1: T-cells - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 52: Non-specific - Mitochondria | Cluster 108: Fibroblasts - ECM organization | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | 1,449 | 1 |
ENSG00000079335 | CDC14A | Cell division cycle 14A | [
"Q9UNH5"
] | 1 | 100345001-100520277 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023783"
] | [
"cdc14",
"Cdc14A1",
"Cdc14A2",
"DFNB105",
"DFNB32"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Hearing"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Nucleoplasm",
"Endoplasmic reticulum"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 41: Basophils - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,450 | 3 |
ENSG00000079337 | RAPGEF3 | Rap guanine nucleotide exchange factor 3 | [
"O95398"
] | 12 | 47734363-47771040 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004386",
"HPA040365",
"HPA043518"
] | [
"bcm910",
"cAMP-GEFI",
"EPAC"
] | [
"Predicted intracellular proteins"
] | [
"Angiogenesis"
] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Cytosol"
] | [
"Endoplasmic reticulum"
] | [] | [] | Uncertain | Approved | null | 2 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 15: Kidney cancer - Membrane components | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 4 | 1 | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,451 | 5 |
ENSG00000079385 | CEACAM1 | CEA cell adhesion molecule 1 | [
"P13688"
] | 19 | 42507304-42561234 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002146",
"HPA011041"
] | [
"BGP",
"BGP1",
"CD66a"
] | [
"CD markers",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | null | Enhanced | null | 6 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 10 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,452 | 5 |
ENSG00000079387 | SENP1 | SUMO specific peptidase 1 | [
"Q9P0U3"
] | 12 | 48042897-48106079 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011765",
"HPA046491"
] | [] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm"
] | [
"Focal adhesion sites"
] | [] | [] | Supported | null | null | 21 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 16: Non-specific - Transcription | Cluster 38: Non-specific - Transcription | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 57: Testis - Spermatogenesis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 1,453 | 3 |
ENSG00000079393 | DUSP13 | Dual specificity phosphatase 13 | [
"Q6B8I1",
"Q9UII6"
] | 10 | 75094432-75109221 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"BEDP",
"DUSP13A",
"DUSP13B",
"FLJ32450",
"MDSP",
"TMDP"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [] | [] | [] | [] | null | null | null | 14 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 33: Sarcoma - Muscle contraction | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 14 | 0 | 0 | 0 | [] | [] | [] | 1,454 | 6 |
ENSG00000079459 | FDFT1 | Farnesyl-diphosphate farnesyltransferase 1 | [
"P37268"
] | 8 | 11795573-11839304 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008874"
] | [
"SQS"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cholesterol biosynthesis",
"Cholesterol metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis",
"Steroid metabolism",
"Sterol biosynthesis",
"Sterol metabolism"
] | [
"Multifunctional enzyme",
"Transferase"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Approved | null | 34 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 49: Hindbrain - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 102: Non-specific - Mixed function | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 4 | 1 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,457 | 4 |
ENSG00000079462 | PAFAH1B3 | Platelet activating factor acetylhydrolase 1b catalytic subunit 3 | [
"Q15102"
] | 19 | 42297033-42303546 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035639"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Intermediate filaments"
] | [] | [] | [] | Approved | Uncertain | null | 17 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 4: Non-specific - Transcription | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 27: Cerebellum - Synaptic function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,458 | 2 |
ENSG00000079482 | OPHN1 | Oligophrenin 1 | [
"O60890"
] | X | 67949349-68433913 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002919"
] | [
"ARHGAP41",
"MRX60",
"OPN1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Neurogenesis"
] | [
"GTPase activation"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 51: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,459 | 9 |
ENSG00000079557 | AFM | Afamin | [
"P43652"
] | 4 | 73481745-73504001 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017006",
"HPA052437"
] | [
"ALB2",
"ALBA"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [] | [
"Secreted to blood"
] | [
"Transport"
] | Uncertain | Enhanced | null | 2 | null | null | null | null | Cluster 55: Lymphoma - Immune response | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 12 | Not detected | Not detected | null | Cancer enriched | Detected in single | 91 | Group enriched | Detected in some | 39 | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,460 | 3 |
ENSG00000079616 | KIF22 | Kinesin family member 22 | [
"Q14807"
] | 16 | 29790727-29805385 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048213",
"HPA075670"
] | [
"Kid",
"KNSL4",
"OBP-1",
"OBP-2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"Motor protein"
] | [
"Disease variant",
"Dwarfism"
] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Enhanced | null | 26 | null | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 33: Neurons - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,461 | 3 |
ENSG00000079689 | SCGN | Secretagogin, EF-hand calcium binding protein | [
"O76038"
] | 6 | 25652201-25701783 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004005",
"HPA006641",
"CAB044060",
"CAB062563",
"CAB068232"
] | [
"CALBL",
"DJ501N12.8",
"SECRET",
"SEGN"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Supported | Enhanced | Supported | 48 | null | null | null | Cluster 16: Non-specific - Transcription | Cluster 10: Ciliated cells - Ion channel activity | Cluster 109: Neurons - Neuronal signaling | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,462 | 5 |
ENSG00000079691 | CARMIL1 | Capping protein regulator and myosin 1 linker 1 | [
"Q5VZK9"
] | 6 | 25279078-25620530 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029038",
"HPA029039"
] | [
"CARMIL",
"dJ501N12.1",
"FLJ20048",
"LRRC16",
"LRRC16A"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Nuclear speckles"
] | [] | [] | Supported | Enhanced | null | 7 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 15: Kidney cancer - Membrane components | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 7: Small intestine - Absorption and Digestion | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,463 | 3 |
ENSG00000079739 | PGM1 | Phosphoglucomutase 1 | [
"P36871"
] | 1 | 63593411-63660245 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004666",
"HPA024190",
"HPA024637",
"HPA046329"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Glucose metabolism"
] | [
"Isomerase"
] | [
"Congenital disorder of glycosylation",
"Disease variant",
"Glycogen storage disease"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 15 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 21: Non-specific - Metabolism | Cluster 15: Kidney cancer - Membrane components | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,464 | 1 |
ENSG00000079805 | DNM2 | Dynamin 2 | [
"P50570"
] | 19 | 10718055-10833488 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054246"
] | [
"CMT2M",
"CMTDI1",
"CMTDIB",
"DI-CMTB",
"DYN2",
"DYNII"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Endocytosis",
"Phagocytosis"
] | [
"Hydrolase",
"Motor protein"
] | [
"Cancer-related genes",
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 65 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 23: Non-specific - Transcription | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,466 | 1 |
ENSG00000079819 | EPB41L2 | Erythrocyte membrane protein band 4.1 like 2 | [
"O43491"
] | 6 | 130839347-131063322 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005730",
"HPA006642"
] | [
"4.1-G",
"4.1G"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Transport"
] | [
"Actin-binding"
] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Cell Junctions"
] | [] | [] | Enhanced | Supported | null | 46 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 30: White matter - Myelination | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,467 | 6 |
ENSG00000079841 | RIMS1 | Regulating synaptic membrane exocytosis 1 | [
"Q86UR5"
] | 6 | 71886550-72403150 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA076565"
] | [
"CORD7",
"KIAA0340",
"RAB3IP2",
"RIM",
"RIM1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Exocytosis",
"Neurotransmitter transport",
"Sensory transduction",
"Transport",
"Vision"
] | [] | [
"Cone-rod dystrophy"
] | [] | [] | [] | [] | null | Enhanced | null | 9 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 64: Connective tissue cells - ECM organization | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 9 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,468 | 4 |
ENSG00000079931 | MOXD1 | Monooxygenase DBH like 1 | [
"Q6UVY6"
] | 6 | 132296055-132401475 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035740"
] | [
"dJ248E1.1",
"DKFZP564G202",
"MOX"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 51: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 33 | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,469 | 3 |
ENSG00000079950 | STX7 | Syntaxin 7 | [
"O15400"
] | 6 | 132445867-132513198 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001467",
"CAB062564"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Lysosomes"
] | [] | [] | [] | Supported | Enhanced | null | 152 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in all | 5 | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,470 | 5 |
ENSG00000079974 | RABL2B | RAB, member of RAS oncogene family like 2B | [
"Q9UNT1"
] | 22 | 50767501-50783667 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042642",
"HPA042700",
"HPA044007"
] | [] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [] | [
"Centrosome",
"Basal body"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 17: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,471 | 4 |
ENSG00000079999 | KEAP1 | Kelch like ECH associated protein 1 | [
"Q14145"
] | 19 | 10486125-10503558 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005558",
"CAB025337"
] | [
"INrf2",
"KIAA0132",
"KLHL19",
"MGC10630",
"MGC1114",
"MGC20887",
"MGC4407",
"MGC9454"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Nucleoplasm",
"Centriolar satellite"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 149 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 28: Oligodendrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,472 | 1 |
ENSG00000080007 | DDX43 | DEAD-box helicase 43 | [
"Q9NXZ2"
] | 6 | 73394828-73417566 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031381"
] | [
"CT13",
"DKFZp434H2114",
"HAGE"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 5 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 49: Hindbrain - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 43: Placenta - Pregnancy hormone signaling | Group enriched | Detected in many | 7 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 14 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,473 | 8 |
ENSG00000080031 | PTPRH | Protein tyrosine phosphatase receptor type H | [
"Q9HD43"
] | 19 | 55181247-55209506 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008708"
] | [
"SAP-1"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Nuclear speckles",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | null | null | 10 | null | null | null | Cluster 30: White matter - Myelination | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 7: Small intestine - Absorption and Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,474 | 6 |
ENSG00000080166 | DCT | Dopachrome tautomerase | [
"P40126"
] | 13 | 94436811-94479682 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010742",
"HPA010743",
"HPA010800",
"CAB017634"
] | [
"TRP-2",
"TRP2",
"TYRP2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Melanin biosynthesis"
] | [
"Isomerase"
] | [
"Albinism",
"Disease variant"
] | [
"Plasma membrane"
] | [
"Vesicles"
] | [] | [] | Supported | Enhanced | null | 7 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in some | 35 | Cancer enriched | Detected in some | 26 | Cancer enriched | Detected in some | 203 | Cell type enriched | Detected in many | 90 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,475 | 4 |
ENSG00000080189 | SLC35C2 | Solute carrier family 35 member C2 | [
"Q9NQQ7"
] | 20 | 46345980-46364458 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027011"
] | [
"bA394O2.1",
"C20orf5",
"CGI-15",
"OVCOV1"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 6 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 19: Astrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,476 | 7 |
ENSG00000080200 | CRYBG3 | Crystallin beta-gamma domain containing 3 | [
"Q68DQ2"
] | 3 | 97822011-97944984 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA075635"
] | [
"DKFZp667G2110"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Primary cilium"
] | [] | [] | Approved | null | null | 9 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 30: White matter - Myelination | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,477 | 2 |
ENSG00000080224 | EPHA6 | EPH receptor A6 | [
"Q9UF33"
] | 3 | 96814581-97761532 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007397"
] | [
"FLJ35246"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Mid piece"
] | [] | [] | [] | Approved | Uncertain | null | 10 | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,478 | 2 |
ENSG00000080293 | SCTR | Secretin receptor | [
"P47872"
] | 2 | 119439843-119525301 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007269"
] | [] | [
"FDA approved drug targets",
"G-protein coupled receptors",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 8: Pancreas - Proteolysis | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,479 | 1 |
ENSG00000080298 | RFX3 | Regulatory factor X3 | [
"P48380"
] | 9 | 3218297-3526004 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035689"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 18 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,480 | 8 |
ENSG00000080345 | RIF1 | Replication timing regulatory factor 1 | [
"Q5UIP0"
] | 2 | 151409883-151508013 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036887",
"HPA036888"
] | [
"FLJ10599",
"FLJ12870"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA damage",
"DNA repair"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear membrane",
"Plasma membrane"
] | [] | [] | Supported | Supported | null | 39 | No | No | Cluster 35: Neutrophils - Protein binding | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 8 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,481 | 5 |
ENSG00000080371 | RAB21 | RAB21, member RAS oncogene family | [
"Q9UL25"
] | 12 | 71754863-71800286 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016988",
"CAB037048"
] | [
"KIAA0118"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Approved | null | 29 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in single | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,482 | 4 |
ENSG00000080493 | SLC4A4 | Solute carrier family 4 member 4 | [
"Q9Y6R1"
] | 4 | 71062667-71572087 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022493",
"HPA035628",
"HPA035629",
"HPA079220"
] | [
"hhNMC",
"HNBC1",
"NBC1",
"NBC2",
"pNBC",
"SLC4A5"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Sodium transport",
"Symport",
"Transport"
] | [] | [
"Disease variant",
"Retinitis pigmentosa"
] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 4 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 15: Kidney cancer - Membrane components | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,483 | 8 |
ENSG00000080503 | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | [
"P51531"
] | 9 | 1980290-2193624 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029981",
"CAB037276"
] | [
"BAF190",
"BRM",
"hBRM",
"hSNF2a",
"SNF2",
"SNF2L2",
"SNF2LA",
"Sth1p",
"SWI2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Hydrolase"
] | [
"Disease variant",
"Hypotrichosis",
"Intellectual disability",
"Schizophrenia"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 85 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 21: Lymphoma - Adaptive immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,484 | 5 |
ENSG00000080511 | RDH8 | Retinol dehydrogenase 8 | [
"Q9NYR8"
] | 19 | 10013249-10022279 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA064473"
] | [
"PRRDH",
"SDR28C2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism",
"Sensory transduction",
"Vision"
] | [
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [
"Midbody ring",
"Cytosol"
] | [] | [] | Approved | null | null | null | Yes | null | null | null | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 28 | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in single | 10 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,485 | 7 |
ENSG00000080546 | SESN1 | Sestrin 1 | [
"Q9Y6P5"
] | 6 | 108984309-109094846 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA073659"
] | [
"PA26",
"SEST1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm"
] | [] | [] | Supported | null | null | 1 | null | null | Cluster 24: Non-specific - Transcription | Cluster 31: Non-specific - Transcription | Cluster 51: Myeloma - Immunoglobulins | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,486 | 2 |
ENSG00000080561 | MID2 | Midline 2 | [
"Q9UJV3"
] | X | 107825755-107931637 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FXY2",
"MRX101",
"RNF60",
"TRIM1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | null | null | 23 | null | null | Cluster 11: T-cells - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 36: Non-specific - mRNA processing | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,487 | 1 |
ENSG00000080572 | DNAAF6 | Dynein axonemal assembly factor 6 | [
"Q9NQM4"
] | X | 107206611-107244247 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051099",
"HPA072496"
] | [
"CXorf41",
"MGC35261",
"NYSAR97",
"PIH1D3",
"TWISTER"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Disease variant",
"Kartagener syndrome",
"Primary ciliary dyskinesia"
] | [
"Golgi apparatus",
"Primary cilium",
"Acrosome"
] | [
"Nucleoplasm",
"Primary cilium tip",
"Basal body",
"Cytosol",
"Equatorial segment"
] | [] | [] | Approved | Enhanced | null | 11 | null | null | null | Cluster 46: Brainstem - Mixed function | null | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in some | 7 | Not detected | Not detected | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,488 | 8 |
ENSG00000080573 | COL5A3 | Collagen type V alpha 3 chain | [
"P25940"
] | 19 | 9959561-10010504 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041695",
"HPA048256"
] | [] | [
"Cancer-related genes",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Plasma membrane"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Approved | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,489 | 5 |
ENSG00000080603 | SRCAP | Snf2 related CREBBP activator protein | [
"Q6ZRS2"
] | 16 | 30698209-30741409 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028929"
] | [
"DOMO1",
"KIAA0309",
"SWR1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"DNA-binding",
"Helicase",
"Hydrolase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Golgi apparatus"
] | [] | [] | Supported | Approved | null | 29 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 54: Non-specific - Transcription | Cluster 22: Non-specific - Basic cellular functions | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,490 | 3 |
ENSG00000080608 | PUM3 | Pumilio RNA binding family member 3 | [
"Q15397"
] | 9 | 2720469-2844095 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002353"
] | [
"HA-8",
"hPUF-A",
"KIAA0020",
"PEN",
"Puf-A",
"PUF6",
"XTP5"
] | [
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"RNA-binding"
] | [] | [
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 82 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 47: Leukemia - Hemostasis | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 1,491 | 3 |
ENSG00000080618 | CPB2 | Carboxypeptidase B2 | [
"Q96IY4"
] | 13 | 46053186-46105033 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004146"
] | [
"CPU",
"PCPB",
"TAFI"
] | [
"Enzymes",
"FDA approved drug targets",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Blood coagulation",
"Fibrinolysis",
"Hemostasis"
] | [
"Carboxypeptidase",
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Blood coagulation"
] | null | Approved | null | null | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 84 | Cancer enriched | Detected in some | 6 | Cancer enriched | Detected in some | 57 | Cell type enriched | Detected in many | 7 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,492 | 6 |
ENSG00000080644 | CHRNA3 | Cholinergic receptor nicotinic alpha 3 subunit | [
"P32297"
] | 15 | 78593052-78621295 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029430"
] | [] | [
"Disease related genes",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Nuclear speckles",
"Plasma membrane"
] | [
"Primary cilium tip",
"Primary cilium transition zone",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 1 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 32: Retina & Lymphoid tissues - Signaling | Group enriched | Detected in some | 6 | Cancer enriched | Detected in some | 20 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,493 | 4 |
ENSG00000080709 | KCNN2 | Potassium calcium-activated channel subfamily N member 2 | [
"Q9H2S1"
] | 5 | 114055926-114496500 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038221"
] | [
"hSK2",
"KCa2.2"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Transport"
] | [
"Calmodulin-binding",
"Ion channel"
] | [
"Disease variant",
"Dystonia",
"FDA approved drug targets",
"Intellectual disability"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Uncertain | Uncertain | null | 1 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,494 | 2 |
ENSG00000080802 | CNOT4 | CCR4-NOT transcription complex subunit 4 | [
"O95628"
] | 7 | 135361795-135510145 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005737"
] | [
"CLONE243",
"NOT4",
"NOT4H"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Ubl conjugation pathway"
] | [
"RNA-binding",
"Transferase"
] | [] | [] | [] | [] | [] | null | Approved | null | 10 | null | null | Cluster 32: Basophils - Transcription | Cluster 16: Non-specific - Transcription | Cluster 39: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,495 | 1 |
ENSG00000080815 | PSEN1 | Presenilin 1 | [
"P49768"
] | 14 | 73136418-73223691 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB006844",
"HPA030760",
"HPA067496"
] | [
"AD3",
"FAD",
"PS1",
"S182"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis",
"Cell adhesion",
"Notch signaling pathway"
] | [
"Hydrolase",
"Protease"
] | [
"Alzheimer disease",
"Amyloidosis",
"Cancer-related genes",
"Cardiomyopathy",
"Disease variant",
"Neurodegeneration"
] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Cell Junctions"
] | [] | [] | Supported | Approved | null | 63 | Yes | No | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 30: Non-specific - Gene expression regulation | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,496 | 1 |
ENSG00000080819 | CPOX | Coproporphyrinogen oxidase | [
"P36551"
] | 3 | 98579446-98593648 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015736",
"HPA054448"
] | [
"CPO",
"CPX",
"HCP"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Heme biosynthesis",
"Porphyrin biosynthesis"
] | [
"Oxidoreductase"
] | [
"Disease variant",
"Hereditary hemolytic anemia"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | null | null | 4 | No | No | Cluster 14: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,497 | 2 |
ENSG00000080822 | CLDND1 | Claudin domain containing 1 | [
"Q9NY35"
] | 3 | 98497912-98523066 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029841"
] | [
"C3orf4",
"Z38"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Approved | Approved | null | 6 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 30: White matter - Myelination | Cluster 59: Leukemia - T-cell receptor | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in all | 14 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 1,498 | 7 |
ENSG00000080823 | MOK | MOK protein kinase | [
"Q9UQ07"
] | 14 | 102224500-102305190 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA027292"
] | [
"RAGE",
"RAGE1",
"STK30"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Endoplasmic reticulum"
] | [
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Approved | null | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 17: Choroid plexus - Cilium | Cluster 72: Neuronal - Signal transduction | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 1,499 | 2 |
ENSG00000080824 | HSP90AA1 | Heat shock protein 90 alpha family class A member 1 | [
"P07900"
] | 14 | 102080742-102139699 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002058",
"HPA047290"
] | [
"FLJ31884",
"Hsp89",
"Hsp90",
"HSP90N",
"HSPC1",
"HSPCA"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Stress response"
] | [
"Chaperone",
"Hydrolase"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 500 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,500 | 3 |
ENSG00000080839 | RBL1 | RB transcriptional corepressor like 1 | [
"P28749"
] | 20 | 36996349-37095997 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054962",
"HPA056525"
] | [
"cp107",
"p107",
"PRB1"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell cycle",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Repressor"
] | [
"Cancer-related genes",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 43 | null | null | Cluster 6: T-cells - T-cell receptor | Cluster 25: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 27: Non-specific - Cell proliferation | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,501 | 5 |
ENSG00000080845 | DLGAP4 | DLG associated protein 4 | [
"Q9Y2H0"
] | 20 | 36306336-36528637 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054105",
"HPA056378"
] | [
"DAP4",
"KIAA0964",
"SAPAP4"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Focal adhesion sites"
] | [] | [] | Approved | Approved | null | 9 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 109: Neurons - Neuronal signaling | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,502 | 3 |
ENSG00000080854 | IGSF9B | Immunoglobulin superfamily member 9B | [
"Q9UPX0"
] | 11 | 133896438-133956968 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA010802"
] | [
"KIAA1030",
"LINC00947",
"LOC283174",
"MIR4697HG"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Neurogenesis"
] | [] | [] | [
"Golgi apparatus",
"Cell Junctions"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 1,503 | 8 |
ENSG00000080910 | CFHR2 | Complement factor H related 2 | [
"P36980"
] | 1 | 196943738-196959622 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038915",
"HPA040726",
"HPA049813"
] | [
"CFHL2",
"FHR2",
"HFL3"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | null | Supported | null | 1 | null | null | null | null | Cluster 7: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in single | 2,834 | Not detected | Not detected | null | Cancer enriched | Detected in single | 660 | Cell type enriched | Detected in some | 144 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,504 | 1 |
ENSG00000080986 | NDC80 | NDC80 kinetochore complex component | [
"O14777"
] | 18 | 2571557-2616635 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066330"
] | [
"HEC",
"HEC1",
"hsNDC80",
"KNTC2",
"TID3"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Nucleoplasm",
"Nuclear speckles"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Supported | null | null | 114 | null | Yes | Cluster 43: Non-specific - Transcription & Translation | Cluster 37: Neurons - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,505 | 3 |
ENSG00000081014 | AP4E1 | Adaptor related protein complex 4 subunit epsilon 1 | [
"Q9UPM8"
] | 15 | 50908672-51005895 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041749",
"HPA041891"
] | [
"AP-4-EPSILON",
"SPG51"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [] | [] | [] | [] | null | Approved | null | 12 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 58: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 1,506 | 3 |
ENSG00000081026 | MAGI3 | Membrane associated guanylate kinase, WW and PDZ domain containing 3 | [
"Q5TCQ9"
] | 1 | 113390515-113685923 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008444"
] | [
"MAGI-3"
] | [
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [] | [
"Cell Junctions"
] | [] | [] | [] | Supported | null | null | 15 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 42: Retina - Visual perception | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,508 | 2 |
ENSG00000081051 | AFP | Alpha fetoprotein | [
"P02771"
] | 4 | 73431138-73456174 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010607",
"HPA023600",
"CAB024283",
"CAB025339",
"CAB080122"
] | [
"FETA",
"HPAFP"
] | [
"Cancer-related genes",
"Disease related genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | Approved | Approved | null | 6 | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in single | 10 | Cancer enriched | Detected in some | 4 | Group enriched | Detected in some | 16 | Cell type enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,510 | 3 |
ENSG00000081052 | COL4A4 | Collagen type IV alpha 4 chain | [
"P53420"
] | 2 | 227002714-227164453 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CA44"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Alport syndrome",
"Cancer-related genes",
"Deafness",
"Disease variant"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | null | null | null | 1 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 38: Sub-cortical - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 57: Podocytes - Glomerular filtration | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,511 | 4 |
ENSG00000081059 | TCF7 | Transcription factor 7 | [
"P36402"
] | 5 | 134114681-134151865 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019403",
"HPA058863",
"HPA070505"
] | [
"TCF-1"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 6 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 8: Immune cells - Immune response | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 80: Thymus - Adaptive immune response | Tissue enriched | Detected in many | 13 | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 0 | 0 | 0 | [] | [] | [] | 1,512 | 8 |
ENSG00000081087 | OSTM1 | Osteoclastogenesis associated transmembrane protein 1 | [
"Q86WC4"
] | 6 | 108029245-108165854 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA010851"
] | [
"GL",
"HSPC019"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Osteopetrosis"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 6 | No | No | Cluster 28: Neutrophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,513 | 1 |
ENSG00000081138 | CDH7 | Cadherin 7 | [
"Q9ULB5"
] | 18 | 65750252-65890337 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA061419"
] | [] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | Supported | null | 1 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 109: Neurons - Neuronal signaling | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,514 | 3 |
ENSG00000081148 | IMPG2 | Interphotoreceptor matrix proteoglycan 2 | [
"Q9BZV3"
] | 3 | 101222546-101320575 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008779",
"HPA015907"
] | [
"IPM200",
"RP56",
"SPACRCAN"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Heparin-binding",
"Receptor"
] | [
"Disease variant",
"Retinitis pigmentosa"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Receptor"
] | null | Enhanced | null | null | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 31 | Group enriched | Detected in some | 6 | Cancer enriched | Detected in single | 13 | Group enriched | Detected in many | 20 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,515 | 1 |
ENSG00000081154 | PCNP | PEST proteolytic signal containing nuclear protein | [
"Q8WW12"
] | 3 | 101574180-101594465 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035011",
"HPA063861"
] | [] | [
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Enhanced | Supported | null | 16 | No | No | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 103: Non-specific - Basic cellular processes | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,516 | 3 |
ENSG00000081177 | EXD2 | Exonuclease 3'-5' domain containing 2 | [
"Q9NVH0"
] | 14 | 69191498-69244020 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002906",
"HPA005848"
] | [
"C14orf114",
"EXDL2",
"FLJ10738"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Exonuclease",
"Hydrolase",
"Nuclease"
] | [] | [
"Mitochondria"
] | [
"Intermediate filaments"
] | [] | [] | Approved | Uncertain | null | 13 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,517 | 8 |
ENSG00000081181 | ARG2 | Arginase 2 | [
"P78540"
] | 14 | 67619920-67651708 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000663",
"CAB009435"
] | [] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Arginine metabolism",
"Immunity",
"Innate immunity",
"Urea cycle"
] | [
"Hydrolase"
] | [
"Cancer-related genes"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 3 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 1,518 | 4 |
ENSG00000081189 | MEF2C | Myocyte enhancer factor 2C | [
"Q06413"
] | 5 | 88717117-88904257 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005533",
"CAB068196",
"CAB068197"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Apoptosis",
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | null | 16 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 53: Neurons - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,519 | 4 |
ENSG00000081237 | PTPRC | Protein tyrosine phosphatase receptor type C | [
"P08575"
] | 1 | 198638457-198757476 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000052",
"HPA000440",
"CAB002800",
"CAB056154",
"CAB068221",
"CAB080251"
] | [
"CD45",
"GP180",
"LCA",
"T200"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Cancer-related genes",
"Disease variant",
"SCID"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Uncertain | Enhanced | null | 15 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 102: Non-specific - Mixed function | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Lung Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,520 | 3 |
ENSG00000081248 | CACNA1S | Calcium voltage-gated channel subunit alpha1 S | [
"Q13698"
] | 1 | 201039512-201112451 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009507",
"HPA048892",
"HPA056815"
] | [
"CACNL1A3",
"Cav1.1",
"HOKPP",
"hypoPP",
"MHS5"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Calmodulin-binding",
"Ion channel",
"Voltage-gated channel"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Acrosome",
"Equatorial segment"
] | [] | [] | [] | Approved | Enhanced | null | 4 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 85 | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in single | 5 | Cell type enriched | Detected in some | 11 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,521 | 1 |
ENSG00000081277 | PKP1 | Plakophilin 1 | [
"Q13835"
] | 1 | 201283452-201332993 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027221",
"CAB033130"
] | [
"B6P"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [
"Developmental protein",
"DNA-binding",
"RNA-binding"
] | [
"Ectodermal dysplasia"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 10 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Group enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 1,522 | 6 |
ENSG00000081307 | UBA5 | Ubiquitin like modifier activating enzyme 5 | [
"Q9GZZ9"
] | 3 | 132654446-132679794 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017235",
"HPA076042"
] | [
"FLJ23251",
"UBE1DC1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability",
"Neurodegeneration"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | 29 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,523 | 8 |
ENSG00000081377 | CDC14B | Cell division cycle 14B | [
"O60729"
] | 9 | 96490241-96619843 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064747"
] | [
"Cdc14B1",
"Cdc14B2",
"CDC14B3",
"hCDC14B"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Nucleoplasm"
] | [
"Cell Junctions",
"Cytosol"
] | [] | [] | Supported | null | null | 12 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 11: White matter - Signal transduction | Cluster 71: Lymphoma - Inflammatory response | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 5 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,525 | 7 |
ENSG00000081479 | LRP2 | LDL receptor related protein 2 | [
"P98164"
] | 2 | 169127109-169362534 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005980",
"HPA064792"
] | [
"DBS",
"gp330"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Endocytosis",
"Hearing",
"Neurogenesis",
"Transport"
] | [
"Receptor"
] | [
"Deafness",
"Disease variant"
] | [
"Cell Junctions"
] | [] | [] | [] | Uncertain | Enhanced | null | 19 | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,527 | 9 |
ENSG00000081665 | ZNF506 | Zinc finger protein 506 | [
"Q5JVG8"
] | 19 | 19785839-19821751 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"DKFZp761G1812"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Lung Adenocarcinoma"
] | [
"Prostate Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Lung Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 1,528 | 5 |
ENSG00000081692 | JMJD4 | Jumonji domain containing 4 | [
"Q9H9V9"
] | 1 | 227730425-227735411 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027260",
"HPA052861"
] | [
"FLJ12517"
] | [
"Predicted intracellular proteins"
] | [] | [
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Plasma membrane"
] | [
"Vesicles"
] | [] | [] | Uncertain | Uncertain | null | 2 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,529 | 1 |
ENSG00000081721 | DUSP12 | Dual specificity phosphatase 12 | [
"Q9UNI6"
] | 1 | 161749758-161757238 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008840"
] | [
"DUSP1",
"YVH1"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 9 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 55: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 97: Non-specific - Cellular respiration | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | 1,530 | 9 |
ENSG00000081760 | AACS | Acetoacetyl-CoA synthetase | [
"Q86V21"
] | 12 | 125065434-125143333 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA058815"
] | [
"ACSF1",
"FLJ12389",
"SUR-5"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Ligase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 14: Neurons - Synaptic function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,531 | 2 |
ENSG00000081791 | DELE1 | DAP3 binding cell death enhancer 1 | [
"Q14154"
] | 5 | 141923855-141942047 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036548",
"HPA061490"
] | [
"DELE",
"KIAA0141"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"DNA damage"
] | [] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Uncertain | Uncertain | null | 6 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 42: Choroid plexus - Mitochondria | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 102: Non-specific - Mixed function | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,532 | 4 |
ENSG00000081800 | SLC13A1 | Solute carrier family 13 member 1 | [
"Q9BZW2"
] | 7 | 123113531-123199972 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053615",
"HPA062714"
] | [
"NAS1",
"NaSi-1"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Sodium transport",
"Sulfate transport",
"Symport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | null | null | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 7 | Not detected | Not detected | null | Group enriched | Detected in some | 186 | Group enriched | Detected in some | 13 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,533 | 6 |
ENSG00000081803 | CADPS2 | Calcium dependent secretion activator 2 | [
"Q86UW7"
] | 7 | 122318411-122886759 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056398"
] | [
"CAPS2"
] | [
"Predicted intracellular proteins"
] | [
"Exocytosis",
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | null | null | 1 | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 10: Ciliated cells - Ion channel activity | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 71: Cerebellum - Nervous system development | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,534 | 6 |
ENSG00000081818 | PCDHB4 | Protocadherin beta 4 | [
"Q9Y5E5"
] | 5 | 141121818-141125623 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA014466"
] | [
"PCDH-BETA4"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Plasma membrane"
] | [
"Nuclear membrane"
] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 22: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 108: Fibroblasts - ECM organization | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,535 | 4 |
ENSG00000081842 | PCDHA6 | Protocadherin alpha 6 | [
"Q9UN73"
] | 5 | 140827958-141012347 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA059326",
"HPA078110"
] | [
"CNR2",
"CNRS2",
"CRNR2",
"PCDH-ALPHA6"
] | [
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Vesicles"
] | [] | [
"Secreted in brain"
] | [
"Cell adhesion"
] | Approved | Enhanced | null | null | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 15: Kidney cancer - Membrane components | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,536 | 7 |
ENSG00000081853 | PCDHGA2 | Protocadherin gamma subfamily A, 2 | [
"Q9Y5H1"
] | 5 | 141338760-141512975 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA008755",
"HPA010580",
"HPA038625"
] | [
"PCDH-GAMMA-A2"
] | [
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Vesicles",
"Plasma membrane"
] | [
"Nucleoplasm",
"Nucleoli",
"Focal adhesion sites",
"Cytosol"
] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,537 | 1 |
ENSG00000081870 | HSPB11 | Heat shock protein family B (small) member 11 | [
"Q9Y547"
] | 1 | 53916574-53945699 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030140"
] | [
"C1orf41",
"FAP232",
"HSPCO34",
"IFT25",
"PP25"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Protein transport",
"Spermatogenesis",
"Stress response",
"Transport"
] | [] | [] | [
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | [] | Approved | Uncertain | null | 62 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 31: Non-specific - Transcription | Cluster 37: Non-specific - mRNA processing | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | 1,538 | 7 |
ENSG00000081913 | PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | [
"O60346"
] | 18 | 62715541-62980433 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA020200"
] | [
"KIAA0606",
"PHLPP",
"PLEKHE1",
"PPM3A",
"SCOP"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Tumor suppressor"
] | [] | [] | [] | [] | null | Approved | null | 28 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 11: White matter - Signal transduction | Cluster 6: Leukemia - Signal transduction | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 7 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,539 | 7 |
ENSG00000081923 | ATP8B1 | ATPase phospholipid transporting 8B1 | [
"O43520"
] | 18 | 57646426-57803315 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018673",
"HPA018674"
] | [
"ATPIC",
"BRIC",
"FIC1",
"PFIC",
"PFIC1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Hearing",
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [
"Disease variant",
"Intrahepatic cholestasis"
] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,540 | 8 |
ENSG00000082014 | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | [
"Q6STE5"
] | 7 | 151238764-151277896 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063955",
"HPA065517"
] | [
"BAF60C",
"CRACD3",
"Rsc6p"
] | [
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 22 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 51: Neurons - Mixed function | Cluster 65: Non-specific - Unknown function | Cluster 110: Mural cells - ECM organization | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,542 | 4 |
ENSG00000082068 | WDR70 | WD repeat domain 70 | [
"Q9NW82"
] | 5 | 37379285-37753435 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043064",
"HPA048149"
] | [
"FLJ10233"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 3 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 6: Non-specific - Immune response | Cluster 29: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,543 | 7 |
ENSG00000082074 | FYB1 | FYN binding protein 1 | [
"O15117"
] | 5 | 39105252-39274528 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025336",
"HPA026796",
"HPA067427"
] | [
"ADAP",
"FYB",
"FYB-120/130",
"SLAP-130"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 14 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 59: Leukemia - T-cell receptor | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 51: Lymphoid tissue - Adaptive immune response | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 1,544 | 7 |
ENSG00000082126 | MPP4 | MAGUK p55 scaffold protein 4 | [
"Q96JB8"
] | 2 | 201644870-201698694 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057393"
] | [
"DLG6"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Actin filaments"
] | [] | [] | Supported | null | null | 2 | No | No | null | Cluster 35: Non-specific - DNA binding | Cluster 72: Neuronal - Signal transduction | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 175 | Cancer enhanced | Detected in many | null | Not detected | Not detected | null | Group enriched | Detected in some | 37 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,545 | 8 |
ENSG00000082146 | STRADB | STE20 related adaptor beta | [
"Q9C0K7"
] | 2 | 201387858-201480846 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026549",
"HPA028520"
] | [
"ALS2CR2",
"CALS-21",
"ILPIP",
"ILPIPA",
"PAPK"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Primary cilium",
"Primary cilium tip"
] | [] | [] | Supported | Approved | null | 13 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 8 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Thyroid Carcinoma"
] | [
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma",
"Thyroid Carcinoma"
] | 1,546 | 8 |
ENSG00000082153 | BZW1 | Basic leucine zipper and W2 domains 1 | [
"Q7L1Q6"
] | 2 | 200810594-200827338 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047288",
"HPA053272"
] | [
"5MP2",
"BZAP45",
"KIAA0005"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Translation regulation"
] | [
"Activator"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 9 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 21: Non-specific - Metabolism | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,547 | 8 |
ENSG00000082175 | PGR | Progesterone receptor | [
"P06401"
] | 11 | 101029624-101129813 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000068",
"HPA004751",
"HPA008428",
"HPA017176",
"CAB055100"
] | [
"NR3C3",
"PR"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"Human disease related genes",
"Nuclear receptors",
"Predicted intracellular proteins",
"Transcription factors",
"Transporters"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 30 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 27: Breast cancer - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Group enriched | Detected in many | 4 | Cancer enriched | Detected in single | 27 | Group enriched | Detected in some | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,548 | 8 |
ENSG00000082196 | C1QTNF3 | C1q and TNF related 3 | [
"Q9BXJ4"
] | 5 | 34017858-34043213 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA064996",
"HPA066011"
] | [
"2310005P21Rik",
"Corcs",
"Cors",
"Cors-26",
"CTRP3"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | Approved | Uncertain | null | 2 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 20: Myeloma - Immune response | Cluster 80: Oligodendrocytes - Myelination | Cluster 42: Retina - Visual perception | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,549 | 3 |
ENSG00000082212 | ME2 | Malic enzyme 2 | [
"P23368"
] | 18 | 50879080-50954257 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008247",
"HPA008880"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Allosteric enzyme",
"Oxidoreductase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 6 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,550 | 7 |
ENSG00000082213 | C5orf22 | Chromosome 5 open reading frame 22 | [
"Q49AR2"
] | 5 | 31532287-31555053 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043062"
] | [
"FLJ11193"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear membrane"
] | [] | [] | [] | Approved | Approved | null | 8 | null | null | Cluster 41: Basophils - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 29: Non-specific - Unknown function | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 5 | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,551 | 6 |
ENSG00000082258 | CCNT2 | Cyclin T2 | [
"O60583"
] | 2 | 134918235-134959342 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005559"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Cyclin"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Supported | null | 14 | null | null | Cluster 24: Non-specific - Transcription | Cluster 55: Non-specific - Transcription | Cluster 56: Non-specific - Sensory perception | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Bladder Urothelial Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma"
] | 1,552 | 5 |
ENSG00000082269 | FAM135A | Family with sequence similarity 135 member A | [
"Q9P2D6"
] | 6 | 70412941-70561174 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031743",
"HPA031744"
] | [
"FLJ20176",
"KIAA1411"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 8 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 31: Non-specific - Transcription | Cluster 28: Non-specific - Nuclear processes | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,553 | 3 |
ENSG00000082293 | COL19A1 | Collagen type XIX alpha 1 chain | [
"Q14993"
] | 6 | 69866556-70212468 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042422"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion",
"Differentiation",
"Myogenesis"
] | [
"Developmental protein"
] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | null | Uncertain | null | null | null | null | Cluster 34: B-cells - Unknown function | Cluster 35: Non-specific - DNA binding | Cluster 69: Skin cancer - ECM organization | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 218 | 0 | 0 | 0 | [] | [] | [] | 1,554 | 6 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.