ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000085998 | POMGNT1 | Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | [
"Q8WZA1"
] | 1 | 46188683-46220305 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044518"
] | [
"FLJ20277",
"LGMD2O",
"MEB",
"MGAT1.2"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Congenital muscular dystrophy",
"Disease variant",
"Dystroglycanopathy",
"Limb-girdle muscular dystrophy",
"Lissencephaly",
"Retinitis pigmentosa"
] | [] | [] | [] | [] | null | Approved | null | 39 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,666 | 6 |
ENSG00000085999 | RAD54L | RAD54 like | [
"Q92698"
] | 1 | 46246461-46278480 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028954",
"HPA051537"
] | [
"hHR54",
"hRAD54",
"RAD54A"
] | [
"Enzymes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-binding",
"Helicase",
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 5 | null | Yes | Cluster 9: T-regs - Cell cycle regulation | Cluster 37: Neurons - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in single | null | 4 | 6 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 1,667 | 4 |
ENSG00000086015 | MAST2 | Microtubule associated serine/threonine kinase 2 | [
"Q6P0Q8"
] | 1 | 45786987-46036122 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039722",
"HPA040155"
] | [
"KIAA0807",
"MAST205"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 25 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 46: Lymphoma - Humoral immune response | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,668 | 4 |
ENSG00000086061 | DNAJA1 | DnaJ heat shock protein family (Hsp40) member A1 | [
"P31689"
] | 9 | 33025273-33039907 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001306",
"CAB033665"
] | [
"dj-2",
"hdj-2",
"HSJ2",
"HSPF4",
"NEDD7"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Cytosol"
] | [
"Microtubules"
] | [] | [] | Supported | Approved | null | 112 | null | Yes | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 43: Non-specific - Basic cellular processes | Cluster 20: Non-specific - Transcription regulation | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,669 | 6 |
ENSG00000086062 | B4GALT1 | Beta-1,4-galactosyltransferase 1 | [
"P15291"
] | 9 | 33104082-33167356 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010806",
"HPA010807"
] | [
"beta4Gal-T1",
"GGTB2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Glycosyltransferase",
"Transferase"
] | [
"Congenital disorder of glycosylation",
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Enhanced | Enhanced | null | 2 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 7: Liver cancer - Metabolism | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 31: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [] | [
"Colon Adenocarcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,670 | 7 |
ENSG00000086102 | NFX1 | Nuclear transcription factor, X-box binding 1 | [
"Q12986"
] | 9 | 33290512-33371157 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA056310",
"HPA061382",
"HPA073519"
] | [
"MGC20369",
"NFX2",
"TEG-42",
"Tex42"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Activator",
"DNA-binding",
"Repressor",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Approved | null | 39 | null | null | Cluster 41: Basophils - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 43: Non-specific - Basic cellular processes | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,672 | 7 |
ENSG00000086159 | AQP6 | Aquaporin 6 | [
"Q13520"
] | 12 | 49967194-49977139 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015278"
] | [
"AQP2L"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 264 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 10 | Not detected | Not detected | null | Cancer enriched | Detected in many | 11 | Group enriched | Detected in some | 15 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,673 | 2 |
ENSG00000086189 | DIMT1 | DIM1 rRNA methyltransferase and ribosome maturation factor | [
"Q9UNQ2"
] | 5 | 62347284-62403943 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042944"
] | [
"DIMT1L",
"HSA9761"
] | [
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [
"Methyltransferase",
"RNA-binding",
"Transferase"
] | [] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Approved | null | 42 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,674 | 9 |
ENSG00000086200 | IPO11 | Importin 11 | [
"Q9UI26"
] | 5 | 62403972-62628582 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065346",
"HPA067097"
] | [
"RanBP11"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 19 | null | null | Cluster 32: Basophils - Transcription | Cluster 21: Non-specific - Metabolism | Cluster 59: Leukemia - T-cell receptor | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 43: Placenta - Pregnancy hormone signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,675 | 7 |
ENSG00000086205 | FOLH1 | Folate hydrolase 1 | [
"Q04609"
] | 11 | 49145092-49208638 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001451",
"HPA010593"
] | [
"FOLH",
"GCP2",
"GCPII",
"NAALAD1",
"NAALAdase",
"PSM",
"PSMA"
] | [
"Cancer-related genes",
"Enzymes",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Carboxypeptidase",
"Dipeptidase",
"Hydrolase",
"Metalloprotease",
"Multifunctional enzyme",
"Protease"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Enhanced | null | null | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 3: Rhabdoid - Membrane components | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 25 | Cancer enriched | Detected in all | 17 | Group enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,676 | 6 |
ENSG00000086232 | EIF2AK1 | Eukaryotic translation initiation factor 2 alpha kinase 1 | [
"Q9BQI3"
] | 7 | 6022247-6059175 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016496",
"CAB022082",
"HPA061675"
] | [
"HCR",
"hHRI",
"HRI",
"KIAA1369"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Protein synthesis inhibitor",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 7 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 67: Non-specific - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,677 | 6 |
ENSG00000086288 | NME8 | NME/NM23 family member 8 | [
"Q8N427"
] | 7 | 37848597-37900397 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"CAB016416",
"HPA019259",
"HPA029572"
] | [
"CILD6",
"DNAI8",
"NM23-H8",
"SPTRX2",
"TXNDC3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Developmental protein",
"Hydrolase"
] | [
"Ciliopathy",
"Primary ciliary dyskinesia"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nuclear speckles",
"Primary cilium"
] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 30: White matter - Myelination | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 44: Bone marrow - Nuclear processes | Group enriched | Detected in some | 10 | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Group enriched | Detected in some | 6 | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,678 | 4 |
ENSG00000086289 | EPDR1 | Ependymin related 1 | [
"Q9UM22"
] | 7 | 37920640-37951936 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB026298",
"HPA072321"
] | [
"EPDR",
"MERP-1",
"MERP1",
"UCC1"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"No annotated function"
] | null | Enhanced | null | 34 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 24: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 1,679 | 2 |
ENSG00000086300 | SNX10 | Sorting nexin 10 | [
"Q9Y5X0"
] | 7 | 26291862-26374383 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015605",
"HPA064782"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Protein transport",
"Transport"
] | [] | [
"Disease variant",
"Osteopetrosis"
] | [
"Nucleoplasm",
"Microtubules"
] | [
"Nucleoli",
"Primary cilium",
"Cytosol"
] | [] | [] | Supported | Approved | null | 6 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 1: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 1,680 | 8 |
ENSG00000086475 | SEPHS1 | Selenophosphate synthetase 1 | [
"P49903"
] | 10 | 13317428-13348298 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037645",
"HPA062118"
] | [
"SPS",
"SPS1"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Enhanced | null | 19 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 44: Non-specific - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,681 | 1 |
ENSG00000086506 | HBQ1 | Hemoglobin subunit theta 1 | [
"P09105"
] | 16 | 180459-181179 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062473"
] | [
"HBQ"
] | [
"Predicted intracellular proteins"
] | [
"Oxygen transport",
"Transport"
] | [] | [] | [
"Lipid droplets"
] | [] | [] | [] | Approved | Enhanced | null | 12 | null | null | Cluster 24: Non-specific - Transcription | Cluster 51: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,683 | 2 |
ENSG00000086589 | RBM22 | RNA binding motif protein 22 | [
"Q9NW64"
] | 5 | 150690792-150701077 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001634"
] | [
"Cwc2",
"FLJ10290",
"fSAP47",
"ZC3H16"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"Transport"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 44 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 55: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 20: Non-specific - Transcription regulation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,687 | 8 |
ENSG00000086619 | ERO1B | Endoplasmic reticulum oxidoreductase 1 beta | [
"Q86YB8"
] | 1 | 236214681-236282019 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028085"
] | [
"ERO1-L(beta)",
"Ero1beta",
"ERO1LB"
] | [
"Predicted intracellular proteins"
] | [
"Electron transport",
"Transport"
] | [
"Oxidoreductase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Transport"
] | null | Enhanced | null | 7 | null | null | Cluster 41: Basophils - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 10: Ciliated cells - Ion channel activity | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,689 | 9 |
ENSG00000086666 | ZFAND6 | Zinc finger AN1-type containing 6 | [
"Q6FIF0"
] | 15 | 80059568-80138393 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034845",
"HPA052746",
"HPA077824"
] | [
"AWP1",
"ZA20D3",
"ZFAND5B"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 6 | null | null | Cluster 32: Basophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,690 | 2 |
ENSG00000086696 | HSD17B2 | Hydroxysteroid 17-beta dehydrogenase 2 | [
"P37059"
] | 16 | 82035004-82098534 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021826",
"HPA050235"
] | [
"HSD17",
"SDR9C2"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis"
] | [
"Oxidoreductase"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Enhanced | null | 8 | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 64: Connective tissue cells - ECM organization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Lung Squamous Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | 1,691 | 8 |
ENSG00000086712 | TXLNG | Taxilin gamma | [
"Q9NUQ3"
] | X | 16786432-16844519 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000297",
"HPA000841"
] | [
"CXorf15",
"FIAT",
"FLJ11209",
"LSR5",
"MGC126621",
"MGC126625",
"TXLNGX"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 31: Non-specific - Transcription | Cluster 36: Non-specific - mRNA processing | Cluster 103: Non-specific - Basic cellular processes | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,692 | 5 |
ENSG00000086717 | PPEF1 | Protein phosphatase with EF-hand domain 1 | [
"O14829"
] | X | 18675909-18827921 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA034577"
] | [
"PPEF",
"PPP7CA"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Plasma membrane"
] | [
"Cytokinetic bridge"
] | [] | [] | Uncertain | null | null | 5 | Yes | null | null | Cluster 30: White matter - Myelination | Cluster 1: Neuronal - Visual perception | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 67: Testis - Mixed function | Group enriched | Detected in some | 6 | Group enriched | Detected in some | 6 | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | 1,693 | 3 |
ENSG00000086730 | LAT2 | Linker for activation of T cells family member 2 | [
"Q9GZY6"
] | 7 | 74199652-74229834 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003462"
] | [
"HSPC046",
"LAB",
"NTAL",
"WBSCR15",
"WBSCR5",
"WSCR5"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Immunity",
"Mast cell degranulation"
] | [] | [
"Williams-Beuren syndrome"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 6: Leukemia - Signal transduction | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,694 | 9 |
ENSG00000086758 | HUWE1 | HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 | [
"Q7Z6Z7"
] | X | 53532096-53686752 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002548",
"CAB022718"
] | [
"Ib772",
"KIAA0312",
"UREB1"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Biological rhythms",
"Differentiation",
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"DNA-binding",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nuclear membrane",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Supported | Approved | null | 221 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 103: Non-specific - Basic cellular processes | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,695 | 1 |
ENSG00000086827 | ZW10 | Zw10 kinetochore protein | [
"O43264"
] | 11 | 113733187-113773735 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011565",
"HPA051253",
"HPA055410"
] | [
"KNTC1AP"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"ER-Golgi transport",
"Mitosis",
"Protein transport",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 50 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,696 | 9 |
ENSG00000086848 | ALG9 | ALG9 alpha-1,2-mannosyltransferase | [
"Q9H6U8"
] | 11 | 111782195-111871581 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038575"
] | [
"DIBD1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Congenital disorder of glycosylation",
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Approved | null | 4 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 24: Non-specific - Unknown function | Cluster 22: Non-specific - Basic cellular functions | Cluster 8: Pancreas - Proteolysis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,697 | 2 |
ENSG00000086967 | MYBPC2 | Myosin binding protein C2 | [
"Q14324"
] | 19 | 50432892-50466321 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042991"
] | [
"fsMyBP-C",
"MGC163408",
"MYBPCF"
] | [
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [
"Actin-binding",
"Muscle protein"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 13 | Group enriched | Detected in some | 17 | Cancer enriched | Detected in some | 12 | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,698 | 9 |
ENSG00000086991 | NOX4 | NADPH oxidase 4 | [
"Q9NPH5"
] | 11 | 89324353-89498187 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"KOX",
"KOX-1"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | null | null | 2 | null | null | null | Cluster 30: White matter - Myelination | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,699 | 5 |
ENSG00000087008 | ACOX3 | Acyl-CoA oxidase 3, pristanoyl | [
"O15254"
] | 4 | 8366282-8440723 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035840",
"HPA035841"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [] | [
"Peroxisomes"
] | [] | [] | [] | Approved | Uncertain | null | 4 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 34: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,700 | 2 |
ENSG00000087053 | MTMR2 | Myotubularin related protein 2 | [
"Q13614"
] | 11 | 95821766-95925315 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049831"
] | [
"CMT4B",
"KIAA1073"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 28 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,701 | 9 |
ENSG00000087074 | PPP1R15A | Protein phosphatase 1 regulatory subunit 15A | [
"O75807"
] | 19 | 48872212-48876059 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB018395",
"HPA020240"
] | [
"GADD34"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Stress response",
"Translation regulation"
] | [] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Approved | null | 22 | null | null | Cluster 41: Basophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 13: Non-specific - Mixed function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,702 | 4 |
ENSG00000087076 | HSD17B14 | Hydroxysteroid 17-beta dehydrogenase 14 | [
"Q9BPX1"
] | 19 | 48813018-48836510 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA021467"
] | [
"DHRS10",
"retSDR3",
"SDR47C1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Fucose metabolism",
"Lipid metabolism",
"Steroid metabolism"
] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Approved | null | 26 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 42: Choroid plexus - Mitochondria | Cluster 5: Rhabdoid - Unknown function | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,703 | 4 |
ENSG00000087085 | ACHE | Acetylcholinesterase (Cartwright blood group) | [
"P22303"
] | 7 | 100889994-100896974 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA027098"
] | [
"YT"
] | [
"Blood group antigen proteins",
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Neurotransmitter degradation"
] | [
"Blood group antigen",
"Hydrolase",
"Serine esterase"
] | [
"FDA approved drug targets"
] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | null | null | 3 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 47: Leukemia - Hemostasis | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in many | 9 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,705 | 7 |
ENSG00000087086 | FTL | Ferritin light chain | [
"P02792"
] | 19 | 48965309-48966879 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020769",
"HPA041602"
] | [
"MGC71996",
"NBIA3"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Iron storage"
] | [] | [
"Cancer-related genes",
"Cataract",
"Disease variant",
"FDA approved drug targets",
"Neurodegeneration"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 123 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,706 | 8 |
ENSG00000087087 | SRRT | Serrate, RNA effector molecule | [
"Q9BXP5"
] | 7 | 100875103-100888664 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042858",
"HPA058379"
] | [
"ARS2",
"Asr2",
"serrate"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"RNA-mediated gene silencing",
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 56 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 25: Non-specific - Transcription | Cluster 39: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,707 | 9 |
ENSG00000087088 | BAX | BCL2 associated X, apoptosis regulator | [
"Q07812"
] | 19 | 48954815-48961798 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004206",
"HPA027878",
"CAB080663",
"CAB080665"
] | [
"BCL2L4"
] | [
"Cancer-related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transporters"
] | [
"Apoptosis",
"Host-virus interaction"
] | [] | [
"Cancer-related genes",
"Tumor suppressor"
] | [
"Vesicles"
] | [
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 44 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,708 | 4 |
ENSG00000087095 | NLK | Nemo like kinase | [
"Q9UBE8"
] | 17 | 28041737-28196381 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018192",
"HPA056511"
] | [] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cell Junctions"
] | [] | [] | Approved | Approved | null | 32 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 53: Neurons - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 45 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,709 | 7 |
ENSG00000087111 | PIGS | Phosphatidylinositol glycan anchor biosynthesis class S | [
"Q96S52"
] | 17 | 28553383-28571794 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018149"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"GPI-anchor biosynthesis"
] | [] | [
"Disease variant",
"Epilepsy"
] | [] | [] | [] | [] | null | Approved | null | 23 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 27: Breast cancer - Unknown function | Cluster 22: Non-specific - Basic cellular functions | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,710 | 1 |
ENSG00000087116 | ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif 2 | [
"O95450"
] | 5 | 179110853-179345461 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA028363",
"HPA028444"
] | [
"ADAM-TS2",
"ADAMTS-3",
"hPCPNI",
"NPI",
"PCINP"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted secreted proteins"
] | [
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Ehlers-Danlos syndrome"
] | [
"Plasma membrane"
] | [
"Vesicles"
] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | Uncertain | null | null | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,711 | 7 |
ENSG00000087128 | TMPRSS11E | Transmembrane serine protease 11E | [
"Q9UL52"
] | 4 | 68447463-68497604 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043816",
"HPA051062"
] | [
"DESC1",
"TMPRSS11E2"
] | [
"Enzymes",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [
"Golgi apparatus"
] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | Approved | Uncertain | null | 2 | null | null | null | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,712 | 8 |
ENSG00000087157 | PGS1 | Phosphatidylglycerophosphate synthase 1 | [
"Q32NB8"
] | 17 | 78378649-78425114 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA022526"
] | [
"DKFZP762M186"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Transferase"
] | [] | [
"Vesicles"
] | [
"Plasma membrane",
"Cell Junctions",
"Mid piece"
] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 71: Lymphoma - Inflammatory response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,714 | 9 |
ENSG00000087191 | PSMC5 | Proteasome 26S subunit, ATPase 5 | [
"P62195"
] | 17 | 63827152-63832026 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017871",
"HPA064293"
] | [
"p45",
"p45/SUG",
"RPT6",
"S8",
"SUG-1",
"SUG1",
"TBP10",
"TRIP1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 235 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 45: Non-specific - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 4 | 0 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,715 | 2 |
ENSG00000087206 | UIMC1 | Ubiquitin interaction motif containing 1 | [
"Q96RL1"
] | 5 | 176905005-177022633 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037503",
"HPA037504"
] | [
"RAP80"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator"
] | [] | [
"Nuclear bodies"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 29 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,716 | 5 |
ENSG00000087237 | CETP | Cholesteryl ester transfer protein | [
"P11597"
] | 16 | 56961923-56983845 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"BPIFF"
] | [
"Candidate cardiovascular disease genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Lipid transport",
"Steroid metabolism",
"Sterol metabolism",
"Transport"
] | [] | [
"Atherosclerosis",
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Transport"
] | null | null | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 43: Hindbrain - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 66: Lymphoid tissue - Immune response | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 4 | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,717 | 3 |
ENSG00000087245 | MMP2 | Matrix metallopeptidase 2 | [
"P08253"
] | 16 | 55389700-55506691 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001939",
"CAB002788"
] | [
"CLG4",
"CLG4A",
"TBE-1"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Angiogenesis",
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | Approved | null | 17 | null | null | null | Cluster 20: Macrophages & Microglia - Immune response | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,718 | 6 |
ENSG00000087250 | MT3 | Metallothionein 3 | [
"P25713"
] | 16 | 56589074-56591088 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004011",
"CAB017779"
] | [
"GIF"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 7 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 15: Kidney cancer - Membrane components | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in many | 13 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in all | 34 | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 4 | 0 | 0 | 0 | [] | [] | [] | 1,719 | 2 |
ENSG00000087258 | GNAO1 | G protein subunit alpha o1 | [
"P09471"
] | 16 | 56191390-56357444 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB008387",
"HPA040878"
] | [
"G-ALPHA-o"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Transducer"
] | [
"Disease variant",
"Epilepsy"
] | [] | [] | [] | [] | null | Enhanced | null | 20 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,721 | 4 |
ENSG00000087263 | OGFOD1 | 2-oxoglutarate and iron dependent oxygenase domain containing 1 | [
"Q8N543"
] | 16 | 56451521-56479104 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003215",
"HPA003722"
] | [
"FLJ10826",
"KIAA1612",
"TPA1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | Approved | 5 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,722 | 4 |
ENSG00000087266 | SH3BP2 | SH3 domain binding protein 2 | [
"P78314"
] | 4 | 2793071-2841098 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036789",
"HPA036790"
] | [
"CRBM",
"RES4-23"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 20 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 19: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,723 | 5 |
ENSG00000087269 | NOP14 | NOP14 nucleolar protein | [
"P78316"
] | 4 | 2937933-2963406 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039596",
"HPA055652"
] | [
"C4orf9",
"NOL14",
"RES4-25",
"UTP2"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"rRNA processing"
] | [] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Approved | null | 52 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 25: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,724 | 3 |
ENSG00000087299 | L2HGDH | L-2-hydroxyglutarate dehydrogenase | [
"Q9H9P8"
] | 14 | 50237563-50312229 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065409",
"HPA069708"
] | [
"C14orf160",
"FLJ12618"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Approved | null | null | null | null | Cluster 46: Basophils - Proteolysis | Cluster 31: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,726 | 3 |
ENSG00000087301 | TXNDC16 | Thioredoxin domain containing 16 | [
"Q9P2K2"
] | 14 | 52430596-52552522 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002543"
] | [
"KIAA1344"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | Approved | Approved | null | 5 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 34: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,727 | 1 |
ENSG00000087302 | RTRAF | RNA transcription, translation and transport factor | [
"Q9Y224"
] | 14 | 51989514-52010694 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039824"
] | [
"C14orf166",
"CGI-99",
"CLE",
"CLE7",
"hCLE1",
"LCRP369",
"RLLM1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 43 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 15: Non-specific - Protein processing | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,728 | 5 |
ENSG00000087303 | NID2 | Nidogen 2 | [
"Q14112"
] | 14 | 52004809-52069059 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052460",
"HPA058772"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Plasma membrane"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | Enhanced | Enhanced | null | 6 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 108: Fibroblasts - ECM organization | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | 1,729 | 7 |
ENSG00000087338 | GMCL1 | Germ cell-less 1, spermatogenesis associated | [
"Q96IK5"
] | 2 | 69829660-69881384 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039579"
] | [
"BTBD13",
"FLJ13057",
"GCL1",
"SPATA29"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Developmental protein"
] | [] | [] | [] | [] | [] | null | Approved | null | 68 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 23: Choroid plexus - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,730 | 9 |
ENSG00000087365 | SF3B2 | Splicing factor 3b subunit 2 | [
"Q13435"
] | 11 | 66050729-66069308 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045028"
] | [
"Cus1",
"SAP145",
"SF3b1",
"SF3b145"
] | [
"Disease related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"mRNA processing",
"mRNA splicing"
] | [] | [
"Disease variant"
] | [
"Nuclear speckles"
] | [] | [] | [] | Enhanced | Supported | null | 200 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 11: White matter - Signal transduction | Cluster 24: Non-specific - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,731 | 4 |
ENSG00000087448 | KLHL42 | Kelch like family member 42 | [
"Q9P2K6"
] | 12 | 27780048-27803040 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA020979"
] | [
"Ctb9",
"KIAA1340",
"KLHDC5"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Ubl conjugation pathway"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 36 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 34: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,732 | 3 |
ENSG00000087460 | GNAS | GNAS complex locus | [
"O95467",
"P63092",
"Q5JWF2"
] | 20 | 58839718-58911192 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB010337",
"HPA018122",
"HPA027478",
"HPA028386"
] | [
"GNAS1",
"GNASXL",
"GPSA",
"NESP",
"NESP55",
"SCG6",
"SgVI"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Hydrolase",
"Transducer"
] | [
"Cancer-related genes",
"Cushing syndrome",
"Disease variant",
"Dwarfism",
"Obesity",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Uncertain | Uncertain | null | 30 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 1: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 1,733 | 1 |
ENSG00000087470 | DNM1L | Dynamin 1 like | [
"O00429"
] | 12 | 32679200-32745650 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009952",
"HPA039324"
] | [
"DRP1",
"DVLP",
"DYMPLE",
"HDYNIV",
"VPS1"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Biological rhythms",
"Endocytosis",
"Necrosis"
] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 41 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 14: Neurons - Synaptic function | Cluster 38: Non-specific - Transcription | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,734 | 3 |
ENSG00000087495 | PHACTR3 | Phosphatase and actin regulator 3 | [
"Q96KR7"
] | 20 | 59577509-59847711 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051834",
"HPA054847"
] | [
"C20orf101",
"PPP1R123"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Protein phosphatase inhibitor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | 9 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in many | 7 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Rectum Adenocarcinoma"
] | 1,736 | 6 |
ENSG00000087502 | ERGIC2 | ERGIC and golgi 2 | [
"Q96RQ1"
] | 12 | 29337352-29381189 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049695"
] | [
"Erv41",
"PTX1"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"ER-Golgi transport",
"Transport"
] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [
"Nucleoli rim"
] | [] | [] | Supported | Approved | null | 38 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,737 | 4 |
ENSG00000087510 | TFAP2C | Transcription factor AP-2 gamma | [
"Q92754"
] | 20 | 56629306-56639283 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016061",
"CAB016079",
"HPA055179",
"HPA057076"
] | [
"AP2-GAMMA",
"ERF1",
"hAP-2g",
"TFAP2G"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 9 | Yes | null | null | Cluster 51: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,738 | 7 |
ENSG00000087589 | CASS4 | Cas scaffold protein family member 4 | [
"Q9NQ75"
] | 20 | 56412112-56460387 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB034217"
] | [
"C20orf32",
"HEFL",
"HEPL"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Group enriched | Detected in many | 7 | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 1,740 | 6 |
ENSG00000087842 | PIR | Pirin | [
"O00625"
] | X | 15384799-15493564 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000697",
"HPA075091"
] | [] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Supported | Approved | null | 2 | null | null | null | Cluster 27: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,741 | 8 |
ENSG00000087884 | AAMDC | Adipogenesis associated Mth938 domain containing | [
"Q9H7C9"
] | 11 | 77821109-77918432 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037918",
"HPA037919"
] | [
"C11orf67",
"CK067",
"FLJ21035",
"PTD015"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 7 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 30: White matter - Myelination | Cluster 24: Non-specific - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,742 | 9 |
ENSG00000087903 | RFX2 | Regulatory factor X2 | [
"P48378"
] | 19 | 5993164-6199572 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048969"
] | [
"FLJ14226"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Cilium biogenesis/degradation",
"Differentiation",
"Spermatogenesis",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [
"Primary cilium",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 11 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 3: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 9 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,743 | 4 |
ENSG00000087995 | METTL2A | Methyltransferase 2A, methylcytidine | [
"Q96IZ6"
] | 17 | 62423875-62453385 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FLJ12760",
"METTL2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Methyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | Cluster 24: Non-specific - Transcription | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 27: Breast cancer - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 1,744 | 6 |
ENSG00000088002 | SULT2B1 | Sulfotransferase family 2B member 1 | [
"O00204"
] | 19 | 48552172-48599425 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041724",
"HPA043539",
"HPA076510"
] | [
"HSST2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid metabolism",
"Steroid metabolism"
] | [
"Transferase"
] | [
"Disease variant",
"Ichthyosis"
] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Enhanced | Enhanced | null | 11 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,745 | 2 |
ENSG00000088035 | ALG6 | ALG6 alpha-1,3-glucosyltransferase | [
"Q9Y672"
] | 1 | 63367575-63438553 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA062536",
"HPA076130"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Congenital disorder of glycosylation",
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 12: Bone cancer - Neuronal signaling | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in single | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 1,746 | 6 |
ENSG00000088038 | CNOT3 | CCR4-NOT transcription complex subunit 3 | [
"O75175"
] | 19 | 54137749-54155681 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006408"
] | [
"KIAA0691",
"LENG2",
"NOT3",
"NOT3H"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"RNA-mediated gene silencing",
"Transcription",
"Transcription regulation",
"Translation regulation"
] | [
"Developmental protein",
"Repressor"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 63 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 4: Non-specific - Transcription | Cluster 102: Non-specific - Mixed function | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,747 | 6 |
ENSG00000088053 | GP6 | Glycoprotein VI platelet | [
"Q9HCN6"
] | 19 | 55013705-55038264 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047611",
"HPA066482"
] | [
"GPVI"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Blood coagulation",
"Hemostasis"
] | [
"Receptor"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Blood coagulation"
] | Supported | Approved | null | 5 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 37: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 102: Non-specific - Mixed function | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,748 | 8 |
ENSG00000088179 | PTPN4 | Protein tyrosine phosphatase non-receptor type 4 | [
"P29074"
] | 2 | 119759922-119984899 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019351"
] | [
"PTPMEG"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 20 | null | null | Cluster 1: T-cells - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,749 | 5 |
ENSG00000088205 | DDX18 | DEAD-box helicase 18 | [
"Q9NVP1"
] | 2 | 117814691-117832377 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035400",
"HPA041056"
] | [
"Has1",
"MrDb"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nucleoli",
"Nucleoli rim",
"Mitotic chromosome"
] | [] | [] | [] | Enhanced | Approved | null | 65 | Yes | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 55: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 20: Non-specific - Transcription regulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,750 | 6 |
ENSG00000088247 | KHSRP | KH-type splicing regulatory protein | [
"Q92945"
] | 19 | 6413102-6424811 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034739",
"HPA056518"
] | [
"FBP2",
"FUBP2",
"KSRP"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"mRNA transport",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"DNA-binding",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 26 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 34: Non-specific - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,751 | 8 |
ENSG00000088256 | GNA11 | G protein subunit alpha 11 | [
"P29992"
] | 19 | 3094362-3123999 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048886"
] | [
"FBH",
"FBH2",
"FHH2",
"HHC2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [
"Hydrolase",
"Transducer"
] | [
"Cancer-related genes",
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 21 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 23: Non-specific - Transcription | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,752 | 6 |
ENSG00000088280 | ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 | [
"Q8TDY4"
] | 1 | 23428563-23484568 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020537",
"HPA020546"
] | [
"CENTB6",
"DDEFL1",
"FLJ20199",
"UPLC1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 7 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 1,753 | 5 |
ENSG00000088305 | DNMT3B | DNA methyltransferase 3 beta | [
"Q9UBC3"
] | 20 | 32762385-32809359 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001595",
"HPA001803",
"CAB069896"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"Activator",
"DNA-binding",
"Methyltransferase",
"Repressor",
"Transferase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 40 | null | Yes | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 34: Testis cancer - Unknown function | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in all | 6 | Cancer enriched | Detected in many | 18 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,755 | 8 |
ENSG00000088320 | REM1 | RRAD and GEM like GTPase 1 | [
"O75628"
] | 20 | 31475288-31484895 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049821"
] | [
"GES",
"REM"
] | [
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 69: Skin cancer - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in single | 4 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 1,756 | 5 |
ENSG00000088325 | TPX2 | TPX2 microtubule nucleation factor | [
"Q9ULW0"
] | 20 | 31739271-31801805 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005487"
] | [
"C20orf1",
"C20orf2",
"DIL-2",
"FLS353",
"HCA519",
"p100"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytokinetic bridge",
"Mitotic spindle"
] | [] | [] | Supported | Enhanced | null | 24 | Yes | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 53: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 6 | 8 | 2 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,757 | 3 |
ENSG00000088367 | EPB41L1 | Erythrocyte membrane protein band 4.1 like 1 | [
"Q9H4G0"
] | 20 | 36091504-36232799 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054104",
"HPA056817"
] | [
"4.1N",
"KIAA0338"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 19 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 1: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 36: Brain & Liver - Signaling | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 10 | 3 | 2 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,759 | 5 |
ENSG00000088386 | SLC15A1 | Solute carrier family 15 member 1 | [
"P46059"
] | 13 | 98683801-98752672 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002827"
] | [
"HPECT1",
"HPEPT1",
"PEPT1"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Peptide transport",
"Protein transport",
"Symport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 1,760 | 6 |
ENSG00000088387 | DOCK9 | Dedicator of cytokinesis 9 | [
"Q9BZ29"
] | 13 | 98793429-99086625 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034061",
"CAB034065",
"HPA043940"
] | [
"KIAA1058",
"ZIZ1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 15 | null | null | Cluster 11: T-cells - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 19: Non-specific - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 7 | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,761 | 4 |
ENSG00000088448 | ANKRD10 | Ankyrin repeat domain 10 | [
"Q9NXR5"
] | 13 | 110878540-110915069 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034211",
"HPA038878",
"HPA038879"
] | [
"FLJ20093"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 5 | null | null | Cluster 24: Non-specific - Transcription | Cluster 30: White matter - Myelination | Cluster 19: Non-specific - Unknown function | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,762 | 4 |
ENSG00000088451 | TGDS | TDP-glucose 4,6-dehydratase | [
"O95455"
] | 13 | 94574054-94596242 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039927",
"HPA040857"
] | [
"SDR2E1",
"TDPGD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Lyase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Approved | Approved | null | 2 | null | No | Cluster 3: Non-specific - Nuclear processes | Cluster 50: Non-specific - Nucleic acid binding | Cluster 19: Non-specific - Unknown function | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 1,763 | 4 |
ENSG00000088538 | DOCK3 | Dedicator of cytokinesis 3 | [
"Q8IZD9"
] | 3 | 50674927-51384198 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037543",
"HPA037544"
] | [
"KIAA0299",
"MOCA",
"PBP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | Supported | 8 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 109: Neurons - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,764 | 7 |
ENSG00000088543 | C3orf18 | Chromosome 3 open reading frame 18 | [
"Q9UK00"
] | 3 | 50558025-50571027 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA012105"
] | [
"G20"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 11 | No | No | Cluster 43: Non-specific - Transcription & Translation | Cluster 2: Neurons - Nucleosome | Cluster 21: Lymphoma - Adaptive immune response | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,765 | 5 |
ENSG00000088682 | COQ9 | Coenzyme Q9 | [
"O75208"
] | 16 | 57447425-57461270 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040918"
] | [
"C16orf49",
"DKFZP434K046"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Ubiquinone biosynthesis"
] | [] | [
"Primary mitochondrial disease"
] | [
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 46 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,766 | 4 |
ENSG00000088726 | TMEM40 | Transmembrane protein 40 | [
"Q8WWA1"
] | 3 | 12733528-12769457 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044165",
"HPA073122"
] | [
"FLJ11036"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 3 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 84: Apical squamous epithelium - Cornification | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,767 | 5 |
ENSG00000088727 | KIF9 | Kinesin family member 9 | [
"Q9HAQ2"
] | 3 | 47227998-47283451 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA022031",
"HPA022033",
"HPA030429"
] | [
"MGC104186"
] | [
"Predicted intracellular proteins"
] | [] | [
"Motor protein"
] | [] | [
"Primary cilium",
"Primary cilium tip",
"Cytosol"
] | [
"Mid piece"
] | [] | [] | Approved | Approved | null | 44 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 17: Choroid plexus - Cilium | Cluster 8: Non-specific - Basic cellular processes | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 6 | 2 | 5 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,768 | 3 |
ENSG00000088756 | ARHGAP28 | Rho GTPase activating protein 28 | [
"Q9P2N2"
] | 18 | 6729716-6915716 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030413",
"HPA030414",
"HPA030415"
] | [
"FLJ10312",
"KIAA1314"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Nucleoplasm",
"Cell Junctions"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 9: Non-specific - Receptor signaling | Cluster 5: Rhabdoid - Unknown function | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 43: Placenta - Pregnancy hormone signaling | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 4 | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 1,769 | 9 |
ENSG00000088766 | CRLS1 | Cardiolipin synthase 1 | [
"Q9UJA2"
] | 20 | 6006093-6040053 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"C20orf155",
"CLS1",
"dJ967N21.6",
"GCD10"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Transferase"
] | [
"Disease variant",
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | null | null | 2 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 39: Astrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 102: Non-specific - Mixed function | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,770 | 9 |
ENSG00000088782 | DEFB127 | Defensin beta 127 | [
"Q9H1M4"
] | 20 | 157454-159163 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"bA530N10.2",
"C20orf73",
"DEF-27"
] | [
"Predicted secreted proteins"
] | [] | [
"Antibiotic",
"Antimicrobial",
"Defensin"
] | [] | [] | [] | [
"Secreted in male reproductive system"
] | [
"Defense"
] | null | null | null | 12 | null | null | null | null | null | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 50: Epididymis - Male reproductive secretion | Tissue enriched | Detected in single | 1,161 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 66 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,771 | 4 |
ENSG00000088808 | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B | [
"Q96KQ4"
] | 14 | 103733195-103847575 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006394",
"CAB015454"
] | [
"ASPP1",
"KIAA0771",
"p53BP2-like",
"p85"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 77 | null | null | Cluster 24: Non-specific - Transcription | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 30: Non-specific - Gene expression regulation | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,772 | 6 |
ENSG00000088812 | ATRN | Attractin | [
"O75882"
] | 20 | 3471018-3651118 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008853"
] | [
"DPPT-L",
"MGCA"
] | [
"Plasma proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Inflammatory response"
] | [
"Receptor"
] | [] | [
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Receptor"
] | Approved | Approved | null | 5 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 62: Non-specific - Plasma proteins | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 26: Kidney & Intestine - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,773 | 4 |
ENSG00000088826 | SMOX | Spermine oxidase | [
"Q9NWM0"
] | 20 | 4120980-4187747 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047117",
"HPA060198"
] | [
"C20orf16",
"dJ779E11.1",
"FLJ20746",
"MGC1010",
"PAO",
"PAOh1",
"SMO"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear membrane",
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Approved | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 19: Astrocytes - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 47: Platelets - Hemostasis | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in many | 5 | Group enriched | Detected in some | 5 | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,774 | 4 |
ENSG00000088827 | SIGLEC1 | Sialic acid binding Ig like lectin 1 | [
"Q9BZZ2"
] | 20 | 3686970-3712600 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053457"
] | [
"CD169",
"dJ1009E24.1",
"FLJ00051",
"FLJ00055",
"FLJ00073",
"FLJ32150",
"sialoadhesin",
"SIGLEC-1",
"SN"
] | [
"CD markers",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Endocytosis"
] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Cell adhesion"
] | null | Supported | null | null | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in many | null | Not detected | Not detected | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 10 | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Testicular Germ Cell Tumor"
] | [
"Testicular Germ Cell Tumor"
] | 1,775 | 9 |
ENSG00000088832 | FKBP1A | FKBP prolyl isomerase 1A | [
"P62942"
] | 20 | 1368977-1393164 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004639",
"HPA051330",
"HPA051798"
] | [
"FKBP-12",
"FKBP1",
"FKBP12",
"FKBP12C",
"PKC12",
"PPIASE"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Isomerase",
"Rotamase"
] | [
"FDA approved drug targets"
] | [
"Golgi apparatus"
] | [
"Primary cilium",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 23 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,776 | 7 |
ENSG00000088833 | NSFL1C | NSFL1 cofactor | [
"Q9UNZ2"
] | 20 | 1442162-1473842 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047108",
"HPA050628"
] | [
"dJ776F14.1",
"p47",
"UBX1",
"UBXD10",
"UBXN2C"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 23 | No | No | Cluster 22: Eosinophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 62: Non-specific - Plasma proteins | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,777 | 1 |
ENSG00000088836 | SLC4A11 | Solute carrier family 4 member 11 | [
"Q8NBS3"
] | 20 | 3227417-3239559 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018120",
"HPA058377"
] | [
"BTR1",
"CDPD1",
"CHED2",
"dJ794I6.2",
"FECD4",
"NaBC1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Anion exchange",
"Ion transport",
"Symport",
"Transport"
] | [] | [
"Corneal dystrophy",
"Deafness",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Uncertain | Uncertain | null | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 72: Kidney - Transmembrane transport | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,778 | 5 |
ENSG00000088854 | DNAAF9 | Dynein axonemal assembly factor 9 | [
"Q5TEA3"
] | 20 | 3249306-3407669 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA052103",
"HPA067418"
] | [
"C20orf194",
"DKFZp434N061"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli fibrillar center",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | No | No | Cluster 2: Dendritic cells - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,779 | 4 |
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