ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000090975 | PITPNM2 | Phosphatidylinositol transfer protein membrane associated 2 | [
"Q9BZ72"
] | 12 | 122983480-123151090 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003414",
"HPA003978"
] | [
"NIR3",
"RDGB2",
"RDGBA2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 2 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 23: Choroid plexus - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 80: Thymus - Adaptive immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 1,891 | 9 |
ENSG00000090989 | EXOC1 | Exocyst complex component 1 | [
"Q9NV70"
] | 4 | 55853648-55905086 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037706",
"HPA044873"
] | [
"BM-102",
"FLJ10893",
"SEC3",
"SEC3L1",
"Sec3p"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Antiviral defense",
"Exocytosis",
"Host-virus interaction",
"Protein transport",
"Transport"
] | [] | [] | [
"Plasma membrane",
"Microtubules"
] | [
"Cytosol"
] | [] | [] | Uncertain | Uncertain | null | 78 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 30: White matter - Myelination | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 7: Non-specific - Transcription | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,892 | 8 |
ENSG00000091009 | RBM27 | RNA binding motif protein 27 | [
"Q9P2N5"
] | 5 | 146203605-146289223 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035944",
"HPA036422"
] | [
"ARRS1",
"KIAA1311",
"Psc1",
"ZC3H20"
] | [
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 24: Non-specific - Transcription | Cluster 31: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,893 | 1 |
ENSG00000091010 | POU4F3 | POU class 4 homeobox 3 | [
"Q15319"
] | 5 | 146338839-146341728 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038215"
] | [
"BRN3C",
"DFNA15",
"DFNA42",
"DFNA52"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 13 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | null | Not detected | Not detected | null | Cancer enriched | Detected in single | 31 | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in single | 14 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Bladder Urothelial Carcinoma"
] | [
"Bladder Urothelial Carcinoma"
] | 1,894 | 4 |
ENSG00000091039 | OSBPL8 | Oxysterol binding protein like 8 | [
"Q9BZF1"
] | 12 | 76351797-76559809 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001309"
] | [
"MST120",
"MSTP120",
"ORP8",
"OSBP10"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 24 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 33: Neurons - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,895 | 6 |
ENSG00000091073 | DTX2 | Deltex E3 ubiquitin ligase 2 | [
"Q86UW9"
] | 7 | 76461676-76505995 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042931"
] | [
"KIAA1528",
"RNF58"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Notch signaling pathway",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Nuclear membrane"
] | [
"Vesicles",
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Approved | null | 129 | null | Yes | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 38: Sub-cortical - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 105: Non-specific - Mixed function | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,896 | 7 |
ENSG00000091106 | NLRC4 | NLR family CARD domain containing 4 | [
"Q9NPP4"
] | 2 | 32224453-32265732 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006592",
"HPA075894"
] | [
"CARD12",
"CLAN",
"CLAN1",
"CLANA",
"CLANB",
"CLANC",
"CLAND",
"CLR2.1",
"ipaf"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Immunity",
"Inflammatory response",
"Innate immunity"
] | [] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | Supported | Uncertain | null | 9 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Group enriched | Detected in many | 7 | 0 | 0 | 0 | [] | [] | [] | 1,897 | 6 |
ENSG00000091127 | PUS7 | Pseudouridine synthase 7 | [
"Q96PZ0"
] | 7 | 105439661-105522271 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024116"
] | [
"FLJ20485"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"tRNA processing"
] | [
"Isomerase"
] | [
"Disease variant",
"Dwarfism",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 42 | null | null | Cluster 24: Non-specific - Transcription | Cluster 37: Neurons - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | 1,898 | 8 |
ENSG00000091128 | LAMB4 | Laminin subunit beta 4 | [
"A4D0S4"
] | 7 | 108023548-108130361 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA020242",
"HPA024247"
] | [] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | null | Approved | null | null | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in some | 15 | Group enriched | Detected in some | 10 | Cancer enriched | Detected in single | 9 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,899 | 3 |
ENSG00000091129 | NRCAM | Neuronal cell adhesion molecule | [
"Q92823"
] | 7 | 108147623-108456717 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012606",
"CAB080588"
] | [
"Bravo",
"KIAA0343"
] | [
"Disease related genes",
"Plasma proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Plasma membrane",
"Primary cilium",
"Cytosol"
] | [
"Secreted in brain"
] | [
"Cell adhesion"
] | Supported | Approved | null | 1 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 72: Neuronal - Signal transduction | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 6 | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 6 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,900 | 2 |
ENSG00000091136 | LAMB1 | Laminin subunit beta 1 | [
"P07942"
] | 7 | 107923799-108003213 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004056",
"HPA004132",
"CAB004256"
] | [
"CLM"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [
"Cancer-related genes",
"Lissencephaly"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | null | Enhanced | null | 36 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,901 | 7 |
ENSG00000091137 | SLC26A4 | Solute carrier family 26 member 4 | [
"O43511"
] | 7 | 107660828-107717809 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042860"
] | [
"DFNB4",
"PDS"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [] | [] | [] | [] | null | Approved | null | 3 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 33: Thyroid gland - Tissue development | Tissue enriched | Detected in some | 29 | Cancer enriched | Detected in some | 7 | Cancer enriched | Detected in some | 10 | Cell type enriched | Detected in many | 4 | Immune cell enriched | Detected in single | 8 | 0 | 0 | 0 | [] | [] | [] | 1,902 | 2 |
ENSG00000091140 | DLD | Dihydrolipoamide dehydrogenase | [
"P09622"
] | 7 | 107891162-107931730 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044849"
] | [
"DLDH",
"E3",
"GCSL",
"LAD",
"OGDC-E3"
] | [
"Citric acid cycle related proteins",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Cytokinetic bridge",
"Primary cilium",
"Principal piece"
] | [] | [] | Approved | Supported | null | 48 | Yes | null | Cluster 42: Non-specific - Vesicular transport | Cluster 45: Non-specific - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,904 | 5 |
ENSG00000091157 | WDR7 | WD repeat domain 7 | [
"Q9Y4E6"
] | 18 | 56651343-57029811 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042074",
"HPA051057"
] | [
"KIAA0541",
"TRAG"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 14 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 13: Non-specific - Mixed function | Cluster 7: Non-specific - Transcription | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,905 | 7 |
ENSG00000091164 | TXNL1 | Thioredoxin like 1 | [
"O43396"
] | 18 | 56597209-56651600 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002828",
"HPA002829",
"CAB016446"
] | [
"TRP32",
"Txl",
"TXNL"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Transport"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | Supported | 16 | null | Yes | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 34: Non-specific - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,906 | 2 |
ENSG00000091181 | IL5RA | Interleukin 5 receptor subunit alpha | [
"Q01344"
] | 3 | 3066324-3126613 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CD125",
"CDw125",
"IL5R"
] | [
"CD markers",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"FDA approved drug targets"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | null | null | null | 9 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 3: Choroid plexus - Cilium | Cluster 50: Lymphoma - Unknown function | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 190 | 0 | 0 | 0 | [] | [] | [] | 1,907 | 5 |
ENSG00000091262 | ABCC6 | ATP binding cassette subfamily C member 6 | [
"O95255"
] | 16 | 16149565-16223522 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038105"
] | [
"ARA",
"EST349056",
"MLP1",
"MRP6",
"PXE",
"URG7"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Sensory transduction",
"Transport",
"Vision"
] | [
"Translocase"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | null | null | 1 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 3: Choroid plexus - Cilium | Cluster 18: Liver cancer - Metabolism | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 7 | Immune cell enriched | Detected in single | 5 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 1,908 | 7 |
ENSG00000091317 | CMTM6 | CKLF like MARVEL transmembrane domain containing 6 | [
"Q9NX76"
] | 3 | 32481312-32502852 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026980",
"HPA063491"
] | [
"CKLFSF6",
"FLJ20396"
] | [
"Predicted membrane proteins"
] | [
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 57 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 8: Immune cells - Immune response | Cluster 8: Non-specific - Basic cellular processes | Cluster 82: Dendritic cells - Antigen presentation | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,909 | 9 |
ENSG00000091428 | RAPGEF4 | Rap guanine nucleotide exchange factor 4 | [
"Q8WZA2"
] | 2 | 172735274-173052893 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004388",
"HPA028968"
] | [
"cAMP-GEFII",
"CGEF2"
] | [
"Predicted intracellular proteins"
] | [
"Exocytosis"
] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Focal adhesion sites"
] | [
"Plasma membrane",
"Basal body",
"Cytosol",
"Mid piece"
] | [] | [] | Approved | Approved | null | 9 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 73: Brain - Neuronal signaling | Tissue enriched | Detected in many | 6 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,911 | 6 |
ENSG00000091482 | SMPX | Small muscle protein X-linked | [
"Q9UHP9"
] | X | 21705978-21758116 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA077360"
] | [
"Chisel",
"Csl",
"DFN6",
"DFNX4"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Deafness",
"Non-syndromic deafness"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | null | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 41: Striated muscle - Muscle contraction | Group enriched | Detected in many | 38 | Group enriched | Detected in some | 9 | Group enriched | Detected in many | 5 | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,913 | 5 |
ENSG00000091483 | FH | Fumarate hydratase | [
"P07954"
] | 1 | 241497511-241519799 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017785",
"HPA025770",
"HPA025948",
"HPA027341",
"CAB080323"
] | [] | [
"Cancer-related genes",
"Citric acid cycle related proteins",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Tricarboxylic acid cycle"
] | [
"Lyase"
] | [
"Cancer-related genes",
"Disease variant",
"Tumor suppressor"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | Supported | 20 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 45: Non-specific - Nuclear processes | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,914 | 4 |
ENSG00000091490 | SEL1L3 | SEL1L family member 3 | [
"Q68CR1"
] | 4 | 25747433-25863760 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039355",
"HPA040045",
"HPA058792"
] | [
"KIAA0746"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Uncertain | Approved | null | null | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 35: Non-specific - DNA binding | Cluster 46: Lymphoma - Humoral immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 34: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,915 | 6 |
ENSG00000091513 | TF | Transferrin | [
"P02787"
] | 3 | 133746040-133796641 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001527",
"HPA005692",
"CAB009538"
] | [
"PRO1557",
"PRO2086"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Ion transport",
"Iron transport",
"Transport"
] | [] | [
"Cancer-related genes",
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Transport"
] | null | Enhanced | null | 47 | null | null | null | Cluster 30: White matter - Myelination | Cluster 18: Liver cancer - Metabolism | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 45: Liver - Metabolism & Coagulation | Group enriched | Detected in all | 5 | Cancer enriched | Detected in many | 5 | Cancer enriched | Detected in many | 26 | Group enriched | Detected in many | 7 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,916 | 8 |
ENSG00000091527 | CDV3 | CDV3 homolog | [
"Q9UKY7"
] | 3 | 133573686-133590261 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029761",
"HPA029762",
"HPA029763"
] | [
"H41"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Nucleoli",
"Plasma membrane"
] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 78: Plasma cells - Antibody production & ER-stress response | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,917 | 1 |
ENSG00000091536 | MYO15A | Myosin XVA | [
"Q9UKN7"
] | 17 | 18108756-18179802 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA078501"
] | [
"DFNB3",
"MYO15"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Hearing"
] | [
"Actin-binding",
"Calmodulin-binding",
"Motor protein",
"Myosin"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 20: Pituitary gland - Hormone signaling | Tissue enriched | Detected in some | 11 | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 4 | 0 | 0 | 0 | [] | [] | [] | 1,918 | 2 |
ENSG00000091542 | ALKBH5 | AlkB homolog 5, RNA demethylase | [
"Q6P6C2"
] | 17 | 18183078-18209954 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007196"
] | [
"FLJ20308",
"OFOXD1"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | 11 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 20: Non-specific - Transcription regulation | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,919 | 7 |
ENSG00000091583 | APOH | Apolipoprotein H | [
"P02749"
] | 17 | 66212033-66256525 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001654",
"HPA003732",
"CAB022214"
] | [
"B2G1",
"BG"
] | [
"Candidate cardiovascular disease genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Heparin-binding"
] | [] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Apolipoprotein"
] | Supported | Enhanced | null | 9 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 564 | Cancer enriched | Detected in some | 46 | Cancer enriched | Detected in many | 211 | Cell type enriched | Detected in some | 55 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,920 | 9 |
ENSG00000091592 | NLRP1 | NLR family pyrin domain containing 1 | [
"Q9C000"
] | 17 | 5499415-5619424 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009189",
"HPA064431"
] | [
"CARD7",
"CLR17.1",
"DEFCAP",
"DKFZp586O1822",
"KIAA0926",
"NAC",
"NALP1",
"SLEV1",
"VAMAS1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Immunity",
"Inflammatory response",
"Innate immunity",
"Necrosis"
] | [
"Hydrolase",
"Protease"
] | [
"Disease variant",
"Ectodermal dysplasia"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 9 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 6: Non-specific - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,921 | 3 |
ENSG00000091622 | PITPNM3 | PITPNM family member 3 | [
"Q9BZ71"
] | 17 | 6451263-6556555 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022432",
"HPA059005"
] | [
"ACKR6",
"CORD5",
"NIR1",
"RDGBA3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cone-rod dystrophy",
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 4 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 23 | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 1,922 | 9 |
ENSG00000091640 | SPAG7 | Sperm associated antigen 7 | [
"O75391"
] | 17 | 4959226-4967817 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024032",
"HPA052394"
] | [
"ACRP",
"FSA-1",
"MGC20134"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 2 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 62: Skeletal muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 1,923 | 9 |
ENSG00000091656 | ZFHX4 | Zinc finger homeobox 4 | [
"Q86UP3"
] | 8 | 76681239-76867281 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023837"
] | [
"FLJ20980",
"ZFH4"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | Uncertain | null | 5 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 7: Non-specific - Transcription | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,925 | 4 |
ENSG00000091664 | SLC17A6 | Solute carrier family 17 member 6 | [
"Q9P2U8"
] | 11 | 22338381-22379503 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"CAB037130",
"HPA039226",
"CAB078204"
] | [
"DNPI",
"VGLUT2"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Ion transport",
"Neurotransmitter transport",
"Phosphate transport",
"Sodium transport",
"Symport",
"Transport"
] | [
"Chloride channel",
"Ion channel"
] | [] | [] | [] | [] | [] | null | Supported | Supported | null | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Group enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,926 | 9 |
ENSG00000091831 | ESR1 | Estrogen receptor 1 | [
"P03372"
] | 6 | 151656691-152129619 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000037",
"HPA000449",
"HPA000450",
"CAB055099",
"CAB072858"
] | [
"ER-alpha",
"Era",
"ESR",
"NR3A1"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Nuclear receptors",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Receptor"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Osteoporosis"
] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 572 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 27: Breast cancer - Unknown function | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,929 | 5 |
ENSG00000091844 | RGS17 | Regulator of G protein signaling 17 | [
"Q9UGC6"
] | 6 | 153004459-153131282 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022276",
"HPA056493"
] | [
"RGS-17",
"RGSZ2"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation",
"Signal transduction inhibitor"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 34 | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 10: Ciliated cells - Ion channel activity | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 1,930 | 8 |
ENSG00000091879 | ANGPT2 | Angiopoietin 2 | [
"O15123"
] | 8 | 6499632-6563409 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011437",
"CAB017626"
] | [
"Ang2"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [
"Angiogenesis",
"Differentiation"
] | [
"Developmental protein"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Developmental protein"
] | null | Approved | null | 5 | null | null | Cluster 34: B-cells - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 4 | 2 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 1,931 | 8 |
ENSG00000091947 | TMEM101 | Transmembrane protein 101 | [
"Q96IK0"
] | 17 | 44011188-44023946 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039739",
"HPA075651"
] | [
"FLJ23987",
"MGC4251"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | null | null | 15 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 19: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 5 | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,932 | 7 |
ENSG00000091972 | CD200 | CD200 molecule | [
"P41217"
] | 3 | 112332347-112362812 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031149"
] | [
"MOX1",
"MOX2",
"MRC",
"OX-2"
] | [
"CD markers",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 34: B-cells - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 69: Skin cancer - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 16 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,933 | 4 |
ENSG00000091986 | CCDC80 | Coiled-coil domain containing 80 | [
"Q76M96"
] | 3 | 112596797-112649530 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002266"
] | [
"CL2",
"DRO1",
"LINC01279",
"SSG1",
"TCONS_00006930",
"URB"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | null | Approved | null | null | null | null | null | Cluster 21: Non-specific - Metabolism | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,934 | 8 |
ENSG00000092010 | PSME1 | Proteasome activator subunit 1 | [
"Q06323"
] | 14 | 24136163-24138967 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006632"
] | [
"IFI5111",
"PA28alpha"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Approved | null | 103 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 7: Non-specific - Ribosome | Cluster 31: Non-specific - Antiviral immune response | Cluster 15: Non-specific - Protein processing | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 1,936 | 3 |
ENSG00000092020 | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma | [
"Q969Q6"
] | 14 | 35085467-35122517 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040835",
"HPA058834"
] | [
"C14orf10",
"FLJ20644",
"G4-1",
"G5PR"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cone-rod dystrophy",
"Deafness",
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Golgi apparatus",
"Actin filaments",
"Primary cilium",
"Cytosol"
] | [] | [] | Supported | Approved | null | 17 | No | No | Cluster 42: Non-specific - Vesicular transport | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,937 | 5 |
ENSG00000092036 | HAUS4 | HAUS augmin like complex subunit 4 | [
"Q9H6D7"
] | 14 | 22946228-22957161 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029803"
] | [
"C14orf94",
"FLJ20424"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 19 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,938 | 6 |
ENSG00000092068 | SLC7A8 | Solute carrier family 7 member 8 | [
"Q9UHI5"
] | 14 | 23125295-23183674 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB046015",
"HPA051950",
"HPA060672"
] | [
"LAT2",
"LPI-PC1"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Antiport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 26 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 23: Choroid plexus - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,942 | 9 |
ENSG00000092094 | OSGEP | O-sialoglycoprotein endopeptidase | [
"Q9NPF4"
] | 14 | 20446401-20455089 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039449",
"HPA039751"
] | [
"GCPL1",
"KAE1",
"OSGEP1",
"PRSMG1",
"TCS3"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Acyltransferase",
"Transferase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 53 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 21: Non-specific - Metabolism | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,943 | 6 |
ENSG00000092098 | RNF31 | Ring finger protein 31 | [
"Q96EP0"
] | 14 | 24146683-24160660 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB009063",
"HPA048745"
] | [
"FLJ10111",
"FLJ23501",
"HOIP",
"Paul",
"ZIBRA"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 67 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 7: Non-specific - Ribosome | Cluster 30: Non-specific - Gene expression regulation | Cluster 22: Non-specific - Basic cellular functions | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 7 | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,945 | 3 |
ENSG00000092108 | SCFD1 | Sec1 family domain containing 1 | [
"Q8WVM8"
] | 14 | 30622291-30737694 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003579"
] | [
"C14orf163",
"KIAA0917",
"RA410",
"SLY1",
"STXBP1L2"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 109 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 23: Choroid plexus - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 1,946 | 3 |
ENSG00000092140 | G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | [
"Q7L622"
] | 14 | 30559158-30620064 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001601"
] | [
"FLJ20333",
"KIAA1333",
"PHF7B"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Ubl conjugation pathway"
] | [
"Developmental protein",
"Transferase"
] | [] | [
"Cytosol"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | Approved | Uncertain | null | 8 | null | Yes | Cluster 45: Eosinophils - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 30: Non-specific - Gene expression regulation | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 5 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,947 | 4 |
ENSG00000092148 | HECTD1 | HECT domain E3 ubiquitin protein ligase 1 | [
"Q9ULT8"
] | 14 | 31100117-31207804 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002929",
"HPA054461"
] | [
"KIAA1131"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Enhanced | Approved | null | 101 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 45: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,948 | 2 |
ENSG00000092199 | HNRNPC | Heterogeneous nuclear ribonucleoprotein C | [
"P07910"
] | 14 | 21209136-21269494 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005223",
"HPA051075",
"CAB075755",
"CAB075756",
"HPA078646"
] | [
"HNRPC"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 241 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 71: Lymphoma - Inflammatory response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,949 | 3 |
ENSG00000092200 | RPGRIP1 | RPGR interacting protein 1 | [
"Q96KN7"
] | 14 | 21280083-21351301 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042955",
"HPA060190"
] | [
"CORD13",
"LCA6",
"RGI1",
"RPGRIP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Sensory transduction",
"Vision"
] | [] | [
"Ciliopathy",
"Cone-rod dystrophy",
"Disease variant",
"Glaucoma",
"Leber congenital amaurosis"
] | [
"Vesicles",
"Microtubules",
"Primary cilium"
] | [
"Cytokinetic bridge",
"Primary cilium tip",
"Cytosol"
] | [] | [] | Approved | Supported | Supported | 28 | Yes | null | Cluster 21: Neutrophils - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Group enriched | Detected in some | 82 | Low cancer specificity | Detected in single | null | Cancer enriched | Detected in single | 4 | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,950 | 4 |
ENSG00000092201 | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit | [
"Q9Y5B9"
] | 14 | 21351476-21384019 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022551",
"HPA049787"
] | [
"CDC68",
"FACT",
"FACTP140",
"FLJ10857",
"FLJ14010",
"SPT16/CDC68"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"DNA replication",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [] | [
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Supported | Enhanced | null | 150 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 16: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 17: Non-specific - RNA processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,951 | 2 |
ENSG00000092203 | TOX4 | TOX high mobility group box family member 4 | [
"O94842"
] | 14 | 21476597-21499175 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001899",
"HPA017880",
"HPA027551"
] | [
"C14orf92",
"KIAA0737",
"LCP1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 25 | null | null | Cluster 41: Basophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,952 | 8 |
ENSG00000092208 | GEMIN2 | Gem nuclear organelle associated protein 2 | [
"O14893"
] | 14 | 39114285-39136973 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB015426",
"HPA046570",
"HPA057114"
] | [
"SIP1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Nucleoli"
] | [] | [] | Supported | Enhanced | null | 45 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 48: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,953 | 3 |
ENSG00000092295 | TGM1 | Transglutaminase 1 | [
"P22735"
] | 14 | 24249114-24264432 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB015159",
"HPA040171",
"HPA070372"
] | [
"ICR2",
"LI",
"LI1",
"TGASE",
"TGK"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Keratinization"
] | [
"Acyltransferase",
"Transferase"
] | [
"Disease variant",
"Ichthyosis"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 60 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,954 | 2 |
ENSG00000092345 | DAZL | Deleted in azoospermia like | [
"Q92904"
] | 3 | 16586792-16670306 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019777",
"HPA047113"
] | [
"DAZH",
"DAZL1",
"DAZLA",
"MGC26406",
"SPGYLA"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis",
"Translation regulation"
] | [
"Developmental protein",
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 6 | null | null | null | null | Cluster 5: Rhabdoid - Unknown function | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 79 | Group enriched | Detected in some | 5 | Cancer enriched | Detected in single | 41 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,956 | 6 |
ENSG00000092377 | TBL1Y | Transducin beta like 1 Y-linked | [
"Q9BQ87"
] | Y | 6910686-7101970 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050857",
"HPA060073"
] | [
"TBL1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Activator"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 11 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 61: BICR 18 - Protein kinases | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 33: Thyroid gland - Tissue development | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,957 | 3 |
ENSG00000092421 | SEMA6A | Semaphorin 6A | [
"Q9H2E6"
] | 5 | 116443555-116574823 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031264",
"HPA031265",
"HPA031267"
] | [
"HT018",
"KIAA1368",
"SEMA",
"SEMA6A1",
"SEMAQ"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Intermediate filaments"
] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 26: Oligodendrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in many | 6 | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,958 | 4 |
ENSG00000092439 | TRPM7 | Transient receptor potential cation channel subfamily M member 7 | [
"Q96QT4"
] | 15 | 50552473-50686797 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035522",
"HPA052173"
] | [
"CHAK1",
"LTRPC7",
"TRP-PLIK"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Calcium transport",
"Ion transport",
"Necrosis",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Amyotrophic lateral sclerosis",
"Disease variant",
"FDA approved drug targets",
"Neurodegeneration",
"Parkinsonism"
] | [
"Vesicles",
"Plasma membrane"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 11 | null | null | Cluster 24: Non-specific - Transcription | Cluster 31: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 69: Parathyroid gland - Mixed function | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,959 | 5 |
ENSG00000092445 | TYRO3 | TYRO3 protein tyrosine kinase | [
"Q06418"
] | 15 | 41557675-41583589 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA071245"
] | [
"Brt",
"Dtk",
"Etk-2",
"Rek",
"RSE",
"Sky",
"Tif"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Kinase",
"Receptor",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Approved | null | 24 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 57: Podocytes - Glomerular filtration | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,960 | 9 |
ENSG00000092470 | WDR76 | WD repeat domain 76 | [
"Q9H967"
] | 15 | 43826980-43868412 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039804",
"HPA040626"
] | [
"FLJ12973"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear bodies"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Approved | Uncertain | null | 70 | null | Yes | Cluster 43: Non-specific - Transcription & Translation | Cluster 2: Neurons - Nucleosome | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 2 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,961 | 3 |
ENSG00000092531 | SNAP23 | Synaptosome associated protein 23 | [
"O00161"
] | 15 | 42491233-42545356 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001214",
"CAB037083",
"CAB037317"
] | [
"HsT17016",
"SNAP23A",
"SNAP23B"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [
"Primary cilium"
] | [] | [] | Supported | Approved | null | 57 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 11: White matter - Signal transduction | Cluster 58: Non-specific - Nuclear processes | Cluster 47: Platelets - Hemostasis | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,963 | 3 |
ENSG00000092607 | TBX15 | T-box transcription factor 15 | [
"Q96SF7"
] | 1 | 118883046-118989556 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052245",
"HPA053713"
] | [
"TBX14"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Approved | Uncertain | null | 10 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 1,964 | 5 |
ENSG00000092758 | COL9A3 | Collagen type IX alpha 3 chain | [
"Q14050"
] | 20 | 62816244-62841159 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040125",
"HPA058323"
] | [
"DJ885L7.4.1",
"EDM3",
"FLJ90759",
"IDD",
"MED"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Deafness",
"Disease variant",
"Dwarfism",
"Stickler syndrome"
] | [
"Nucleoplasm"
] | [
"Intermediate filaments"
] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Supported | null | 5 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 69: Skin cancer - ECM organization | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,966 | 8 |
ENSG00000092820 | EZR | Ezrin | [
"P15311"
] | 6 | 158765741-158819368 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004035",
"HPA021616",
"CAB047324",
"CAB075739"
] | [
"VIL2"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell shape"
] | [] | [
"Cancer-related genes"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | null | 124 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 8: Immune cells - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,967 | 6 |
ENSG00000092841 | MYL6 | Myosin light chain 6 | [
"P60660"
] | 12 | 56158346-56163496 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046859",
"HPA063034"
] | [
"ESMLC",
"MLC1SM",
"MLC3NM"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Motor protein",
"Muscle protein",
"Myosin"
] | [] | [] | [] | [] | [] | null | Approved | null | 58 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 44: Non-specific - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,968 | 3 |
ENSG00000092847 | AGO1 | Argonaute RISC component 1 | [
"Q9UL18"
] | 1 | 35869808-35930532 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA067849"
] | [
"EIF2C1",
"hAGO1"
] | [
"Predicted intracellular proteins"
] | [
"RNA-mediated gene silencing",
"Transcription",
"Transcription regulation",
"Translation regulation"
] | [
"Repressor",
"Ribonucleoprotein",
"RNA-binding"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Cytoplasmic bodies"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 52 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 7: Non-specific - Ribosome | Cluster 51: Myeloma - Immunoglobulins | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,969 | 9 |
ENSG00000092850 | TEKT2 | Tektin 2 | [
"Q9UIF3"
] | 1 | 36084094-36088275 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027461"
] | [
"TEKTB1"
] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [] | [
"Connecting piece"
] | [
"Flagellar centriole",
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Approved | null | 9 | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in many | 8 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 13 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,970 | 9 |
ENSG00000092853 | CLSPN | Claspin | [
"Q9HAW4"
] | 1 | 35720218-35769978 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026305",
"HPA026312"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA damage",
"DNA repair"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | [] | Enhanced | null | null | 39 | Yes | Yes | null | Cluster 51: Neurons - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Stomach Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 1,971 | 7 |
ENSG00000092871 | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase | [
"Q8WZ73"
] | 17 | 35005990-35089319 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB008096",
"HPA017910",
"HPA019492"
] | [
"CARP-2",
"CARP2",
"fring",
"rififylin",
"RNF189",
"RNF34L"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 16 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 30: White matter - Myelination | Cluster 55: Lymphoma - Immune response | Cluster 7: Non-specific - Transcription | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,972 | 7 |
ENSG00000092929 | UNC13D | Unc-13 homolog D | [
"Q70J99"
] | 17 | 75827225-75844785 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA067117",
"HPA073525"
] | [
"Munc13-4"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Exocytosis"
] | [] | [
"Familial hemophagocytic lymphohistiocytosis"
] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 6: Non-specific - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,973 | 3 |
ENSG00000092931 | MFSD11 | Major facilitator superfamily domain containing 11 | [
"O43934"
] | 17 | 76735865-76781449 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022001"
] | [
"FLJ20226",
"FLJ22196"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 10 | null | No | Cluster 33: Non-specific - ATP binding | Cluster 16: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,974 | 8 |
ENSG00000092964 | DPYSL2 | Dihydropyrimidinase like 2 | [
"Q16555"
] | 8 | 26514031-26658178 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002381",
"CAB018719"
] | [
"CRMP2",
"DHPRP2",
"DRP-2",
"DRP2"
] | [
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [] | [
"Microtubules",
"Cytosol"
] | [
"Plasma membrane",
"Cytokinetic bridge",
"Mitotic spindle",
"Primary cilium"
] | [] | [] | Supported | Supported | null | 38 | Yes | null | Cluster 2: Dendritic cells - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,975 | 1 |
ENSG00000092969 | TGFB2 | Transforming growth factor beta 2 | [
"P61812"
] | 1 | 218345336-218444619 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006134"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [] | [
"Growth factor",
"Mitogen"
] | [
"Aortic aneurysm",
"Cancer-related genes",
"Disease variant"
] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Growth factor"
] | Approved | null | null | 2 | null | Yes | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 72: Neuronal - Signal transduction | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 43: Placenta - Pregnancy hormone signaling | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,976 | 9 |
ENSG00000092978 | GPATCH2 | G-patch domain containing 2 | [
"Q9NW75"
] | 1 | 217426992-217631090 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027181",
"HPA027322"
] | [
"CT110",
"FLJ10252",
"GPATC2",
"Pfa1",
"PPP1R30"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Uncertain | null | 12 | null | null | Cluster 41: Basophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 1,977 | 8 |
ENSG00000093000 | NUP50 | Nucleoporin 50 | [
"Q9UKX7"
] | 22 | 45163925-45188017 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047162",
"HPA048328"
] | [
"NPAP60L"
] | [
"Essential proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA transport",
"Protein transport",
"Translocation",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Nuclear membrane"
] | [] | [] | [] | Enhanced | Enhanced | null | 50 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 5: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,978 | 2 |
ENSG00000093009 | CDC45 | Cell division cycle 45 | [
"O75419"
] | 22 | 19479457-19520612 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000614",
"CAB009459"
] | [
"CDC45L",
"CDC45L2"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA replication"
] | [] | [
"Disease variant",
"Dwarfism"
] | [
"Nucleoplasm"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 58 | null | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 47: Endothelial cells - Vasculature | Cluster 66: Non-specific - Mitochondria | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 4 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,979 | 3 |
ENSG00000093010 | COMT | Catechol-O-methyltransferase | [
"P21964"
] | 22 | 19941371-19969975 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001169",
"CAB011233"
] | [] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Catecholamine metabolism",
"Lipid metabolism",
"Neurotransmitter degradation"
] | [
"Methyltransferase",
"Transferase"
] | [
"FDA approved drug targets",
"Schizophrenia"
] | [
"Vesicles"
] | [
"Endoplasmic reticulum"
] | [] | [] | Enhanced | Enhanced | null | 62 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,980 | 4 |
ENSG00000093072 | ADA2 | Adenosine deaminase 2 | [
"Q9NZK5"
] | 22 | 17178790-17258235 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA007888"
] | [
"ADGF",
"CECR1",
"IDGFL"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Heparin-binding",
"Hydrolase"
] | [
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Uncertain | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,981 | 6 |
ENSG00000093144 | ECHDC1 | Ethylmalonyl-CoA decarboxylase 1 | [
"Q9NTX5"
] | 6 | 127288712-127343609 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035445",
"HPA035446"
] | [
"dJ351K20.2"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Lyase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 28: Non-specific - Nuclear processes | Cluster 89: Adipocytes - Lipid metabolism | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,982 | 5 |
ENSG00000093167 | LRRFIP2 | LRR binding FLII interacting protein 2 | [
"Q9Y608"
] | 3 | 37052626-37183689 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035956",
"HPA042023"
] | [
"HUFI-2"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Wnt signaling pathway"
] | [] | [] | [
"Plasma membrane",
"Actin filaments"
] | [] | [] | [] | Approved | Uncertain | null | 13 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 8: Non-specific - Basic cellular processes | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Thyroid Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | 1,983 | 3 |
ENSG00000093217 | XYLB | Xylulokinase | [
"O75191"
] | 3 | 38346760-38421348 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037863",
"HPA038415"
] | [
"FLJ10343",
"FLJ12539"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Xylose metabolism"
] | [
"Kinase",
"Transferase"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 8: Non-specific - Basic cellular processes | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,985 | 9 |
ENSG00000094631 | HDAC6 | Histone deacetylase 6 | [
"Q9UBN7"
] | X | 48801377-48824982 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003714",
"CAB004236",
"HPA026321"
] | [
"FLJ16239",
"HD6",
"JM21",
"KIAA0901",
"PPP1R90"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Autophagy",
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Actin-binding",
"Chromatin regulator",
"Hydrolase",
"Repressor",
"Transferase"
] | [
"FDA approved drug targets"
] | [
"Centrosome",
"Basal body",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Supported | null | 205 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 36: Non-specific - mRNA processing | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,986 | 7 |
ENSG00000094661 | OR1I1 | Olfactory receptor family 1 subfamily I member 1 | [
"O60431"
] | 19 | 15082211-15092970 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [] | [
"OR19-20",
"OR1I1P",
"OR1I1Q"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [
"Olfaction",
"Sensory transduction"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 14: Non-specific - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 56: Non-specific - Sensory perception | Cluster 79: Photoreceptor cells - Phototransduction | null | Not detected | Not detected | null | Not detected | Not detected | null | Low cancer specificity | Detected in single | null | Cell type enhanced | Detected in single | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,987 | 2 |
ENSG00000094755 | GABRP | Gamma-aminobutyric acid type A receptor subunit pi | [
"O00591"
] | 5 | 170763350-170814047 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"CAB014883"
] | [] | [
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 3: Rhabdoid - Membrane components | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,988 | 3 |
ENSG00000094796 | KRT31 | Keratin 31 | [
"Q15323"
] | 17 | 41393721-41397608 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049550",
"HPA055194"
] | [
"Ha-1",
"KRTHA1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol",
"Principal piece",
"End piece"
] | [
"Equatorial segment",
"Mid piece"
] | [] | [] | Approved | Enhanced | null | 324 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 9: Skin - Hair follicle development | Tissue enriched | Detected in some | 7 | Not detected | Not detected | null | Cancer enriched | Detected in single | 8 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,989 | 6 |
ENSG00000094804 | CDC6 | Cell division cycle 6 | [
"Q99741"
] | 17 | 40287879-40304657 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050114",
"HPA065070"
] | [
"CDC18L"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA replication",
"Mitosis"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Cytokinetic bridge",
"Mitotic spindle"
] | [] | [] | Approved | Approved | null | 29 | Yes | Yes | Cluster 13: Non-specific - Mitochondria | Cluster 53: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 5 | 6 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,990 | 1 |
ENSG00000094841 | UPRT | Uracil phosphoribosyltransferase homolog | [
"Q96BW1"
] | X | 75156388-75304885 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000805"
] | [
"DKFZp781E1243",
"FUR1",
"MGC23937",
"RP11-311P8.3"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Uncertain | null | 13 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 36: Non-specific - mRNA processing | Cluster 84: Apical squamous epithelium - Cornification | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,991 | 6 |
ENSG00000094880 | CDC23 | Cell division cycle 23 | [
"Q9UJX2"
] | 5 | 138187650-138213343 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039593"
] | [
"ANAPC8",
"APC8",
"CUT23"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Ubl conjugation pathway"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 152 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 34: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,992 | 8 |
ENSG00000094914 | AAAS | Aladin WD repeat nucleoporin | [
"Q9NRG9"
] | 12 | 53307456-53324864 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040086"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA transport",
"Protein transport",
"Translocation",
"Transport"
] | [] | [
"Disease variant"
] | [
"Nuclear membrane"
] | [
"Nucleoplasm",
"Centrosome",
"Cytosol",
"End piece"
] | [] | [] | Supported | Approved | null | 16 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,993 | 9 |
ENSG00000094963 | FMO2 | Flavin containing dimethylaniline monoxygenase 2 | [
"Q99518"
] | 1 | 171185249-171212686 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028261"
] | [] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Monooxygenase",
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 44: Connective tissue cells - ECM organization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Not detected | Not detected | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Stomach Adenocarcinoma"
] | 1,995 | 4 |
ENSG00000094975 | SUCO | SUN domain containing ossification factor | [
"Q9UBS9"
] | 1 | 172532349-172611833 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047251"
] | [
"C1orf9",
"CH1",
"OPT",
"SLP1"
] | [
"Predicted membrane proteins"
] | [
"Osteogenesis"
] | [
"Developmental protein"
] | [] | [
"Nucleoli fibrillar center",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 32: Basophils - Transcription | Cluster 55: Non-specific - Transcription | Cluster 5: Rhabdoid - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 40: Non-specific - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 1,996 | 4 |
ENSG00000095002 | MSH2 | MutS homolog 2 | [
"P43246"
] | 2 | 47403067-47663146 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009572",
"HPA066845",
"CAB070867",
"CAB080131"
] | [
"COCA1",
"HNPCC",
"HNPCC1",
"MSH-2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Hereditary nonpolyposis colorectal cancer",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 79 | null | Yes | Cluster 3: Non-specific - Nuclear processes | Cluster 31: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,997 | 5 |
ENSG00000095015 | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1 | [
"Q13233"
] | 5 | 56815549-56896152 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB004500",
"HPA046509"
] | [
"MAPKKK1",
"MEKK",
"MEKK1"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 45 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 42: Choroid plexus - Mitochondria | Cluster 6: Leukemia - Signal transduction | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,998 | 5 |
ENSG00000095059 | DHPS | Deoxyhypusine synthase | [
"P49366"
] | 19 | 12675717-12681880 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014461",
"HPA029413"
] | [
"MIG13"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Hypusine biosynthesis"
] | [
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 26 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 15: Non-specific - Protein processing | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,999 | 9 |
ENSG00000095066 | HOOK2 | Hook microtubule tethering protein 2 | [
"Q96ED9"
] | 19 | 12763003-12872740 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043519",
"HPA050351"
] | [
"HK2"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 27 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 32: Cerebral cortex - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 6 | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 2,000 | 9 |
ENSG00000095110 | NXPE1 | Neurexophilin and PC-esterase domain family member 1 | [
"Q8N323"
] | 11 | 114518934-114559881 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049133"
] | [
"FAM55A",
"MGC34290"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | null | Enhanced | null | 5 | null | null | null | Cluster 26: Oligodendrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 17: Intestine - Digestion | Tissue enriched | Detected in some | 15 | Not detected | Not detected | null | Group enriched | Detected in some | 23 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 2,001 | 8 |
ENSG00000095139 | ARCN1 | Archain 1 | [
"P48444"
] | 11 | 118572390-118603033 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037573",
"HPA044874"
] | [
"COPD"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [
"Dwarfism"
] | [
"Vesicles"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | Approved | Approved | null | 45 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 24: Non-specific - Unknown function | Cluster 78: Plasma cells - Antibody production & ER-stress response | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,002 | 4 |
ENSG00000095203 | EPB41L4B | Erythrocyte membrane protein band 4.1 like 4B | [
"Q9H329"
] | 9 | 109171974-109321059 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA042862"
] | [
"EHM2",
"LULU2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,003 | 5 |
ENSG00000095209 | TMEM38B | Transmembrane protein 38B | [
"Q9NVV0"
] | 9 | 105694541-105776629 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018465"
] | [
"bA219P18.1",
"C9orf87",
"D4Ertd89e",
"FLJ10493",
"TRIC-B"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel"
] | [
"Osteogenesis imperfecta"
] | [] | [] | [] | [] | null | Uncertain | null | 5 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 55: Non-specific - Transcription | Cluster 43: Non-specific - Basic cellular processes | Cluster 55: Myocytes - Oxidative muscle function | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,004 | 1 |
ENSG00000095261 | PSMD5 | Proteasome 26S subunit, non-ATPase 5 | [
"Q16401"
] | 9 | 120815496-120842951 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003216"
] | [
"KIAA0072",
"S5B"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Centrosome",
"Basal body",
"Connecting piece",
"Mid piece"
] | [] | [] | Approved | Uncertain | null | 78 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 55: Non-specific - Transcription | Cluster 43: Non-specific - Basic cellular processes | Cluster 7: Non-specific - Transcription | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,005 | 4 |
ENSG00000095319 | NUP188 | Nucleoporin 188 | [
"Q5SRE5"
] | 9 | 128947699-129007096 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA061750",
"HPA063942"
] | [
"KIAA0169"
] | [
"Disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"mRNA transport",
"Protein transport",
"Translocation",
"Transport"
] | [] | [
"Cataract",
"Disease variant",
"Microphthalmia"
] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Approved | Approved | null | 15 | No | No | Cluster 33: Non-specific - ATP binding | Cluster 25: Non-specific - Transcription | Cluster 43: Non-specific - Basic cellular processes | Cluster 103: Non-specific - Basic cellular processes | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,007 | 6 |
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