ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000088876 | ZNF343 | Zinc finger protein 343 | [
"Q6P1L6"
] | 20 | 2481817-2524702 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030587",
"HPA052438"
] | [
"MGC10715"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 19 | null | null | Cluster 18: Non-specific - Translation | Cluster 15: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,780 | 7 |
ENSG00000088881 | EBF4 | EBF family member 4 | [
"Q9BQW3"
] | 20 | 2692780-2760108 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"COE4",
"KIAA1442",
"O/E-4",
"RP5-860F19.3"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 1,781 | 6 |
ENSG00000088882 | CPXM1 | Carboxypeptidase X, M14 family member 1 | [
"Q96SM3"
] | 20 | 2794074-2800627 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"CPX-1",
"CPX1",
"CPXM"
] | [
"Enzymes",
"Predicted secreted proteins"
] | [] | [
"Carboxypeptidase",
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | null | null | null | null | null | null | Cluster 14: Non-specific - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in some | 5 | Immune cell enhanced | Detected in single | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 1,782 | 6 |
ENSG00000088888 | MAVS | Mitochondrial antiviral signaling protein | [
"Q7Z434"
] | 20 | 3846799-3876123 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009187",
"HPA049850",
"HPA053524"
] | [
"Cardif",
"IPS-1",
"KIAA1271",
"VISA"
] | [
"Predicted membrane proteins"
] | [
"Antiviral defense",
"Host-virus interaction",
"Immunity",
"Innate immunity"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 115 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 30: White matter - Myelination | Cluster 62: Non-specific - Plasma proteins | Cluster 47: Platelets - Hemostasis | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,783 | 5 |
ENSG00000088899 | LZTS3 | Leucine zipper tumor suppressor family member 3 | [
"O60299"
] | 20 | 3162617-3173549 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA031008",
"HPA031009"
] | [
"KIAA0552",
"ProSAPiP1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 3 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,784 | 5 |
ENSG00000088926 | F11 | Coagulation factor XI | [
"P03951"
] | 4 | 186266189-186289681 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039808"
] | [
"FXI"
] | [
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Blood coagulation",
"Hemostasis"
] | [
"Heparin-binding",
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Blood coagulation"
] | Approved | null | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in some | 12 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,785 | 5 |
ENSG00000088930 | XRN2 | 5'-3' exoribonuclease 2 | [
"Q9H0D6"
] | 20 | 21303331-21389825 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047118",
"HPA050485"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"Transcription",
"Transcription regulation",
"Transcription termination"
] | [
"DNA-binding",
"Exonuclease",
"Hydrolase",
"Nuclease"
] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Supported | null | 53 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 62: Non-specific - Plasma proteins | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,786 | 3 |
ENSG00000088970 | KIZ | Kizuna centrosomal protein | [
"Q2M2Z5"
] | 20 | 21125983-21246622 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"C20orf19",
"HT013",
"NCRNA00153",
"PLK1S1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Retinitis pigmentosa"
] | [] | [] | [] | [] | null | null | null | 8 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 26: Oligodendrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,787 | 6 |
ENSG00000088986 | DYNLL1 | Dynein light chain LC8-type 1 | [
"P63167"
] | 12 | 120469850-120498493 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039954"
] | [
"DLC1",
"DLC8",
"DNCL1",
"hdlc1",
"LC8",
"PIN"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"DNA damage",
"Host-virus interaction",
"Transcription",
"Transcription regulation",
"Transport"
] | [
"Activator",
"Motor protein"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol",
"Mid piece",
"Principal piece"
] | [] | [] | [] | Approved | null | null | 430 | null | Yes | Cluster 10: Non-specific - Membrane trafficking | Cluster 14: Neurons - Synaptic function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 1,788 | 7 |
ENSG00000088992 | TESC | Tescalcin | [
"Q96BS2"
] | 12 | 117038923-117099479 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053200"
] | [
"CHP3",
"FLJ20607",
"TSC"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Protein transport",
"Transport"
] | [
"Protein kinase inhibitor"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 8 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,789 | 2 |
ENSG00000089006 | SNX5 | Sorting nexin 5 | [
"Q9Y5X3"
] | 20 | 17941597-17968980 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020679",
"HPA051187",
"HPA076450"
] | [] | [
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Host-virus interaction",
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 29 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 18: Liver cancer - Metabolism | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,790 | 2 |
ENSG00000089012 | SIRPG | Signal regulatory protein gamma | [
"Q9P1W8"
] | 20 | 1629152-1657779 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"bA77C3.1",
"CD172g",
"SIRP-B2",
"SIRPB2",
"SIRPgamma"
] | [
"CD markers",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | null | null | 2 | null | null | Cluster 39: T-cells - T-cell receptor | null | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 1,792 | 7 |
ENSG00000089022 | MAPKAPK5 | MAPK activated protein kinase 5 | [
"Q8IW41"
] | 12 | 111842228-111902222 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004546",
"HPA015515"
] | [
"MK5",
"PRAK"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 10 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 16: Non-specific - Transcription | Cluster 38: Non-specific - Transcription | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,793 | 3 |
ENSG00000089041 | P2RX7 | Purinergic receptor P2X 7 | [
"Q99572"
] | 12 | 121132819-121188032 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034968",
"HPA042013",
"HPA044141"
] | [
"MGC20089",
"P2X7"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [] | [] | [] | [] | [] | null | Approved | null | 10 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 51: Myeloma - Immunoglobulins | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 0 | 0 | 0 | [] | [] | [] | 1,794 | 6 |
ENSG00000089048 | ESF1 | ESF1 nucleolar pre-rRNA processing protein homolog | [
"Q9H501"
] | 20 | 13714322-13784919 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047083",
"HPA050396"
] | [
"bA526K24.1",
"C20orf6"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Approved | Supported | null | 19 | null | null | Cluster 24: Non-specific - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 17: Non-specific - RNA processing | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,795 | 5 |
ENSG00000089050 | RBBP9 | RB binding protein 9, serine hydrolase | [
"O75884"
] | 20 | 18486540-18497225 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015830",
"HPA049005"
] | [
"Bog"
] | [
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 3 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 3: Rhabdoid - Membrane components | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 16: Liver & Kidney - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,796 | 4 |
ENSG00000089053 | ANAPC5 | Anaphase promoting complex subunit 5 | [
"Q9UJX4"
] | 12 | 121308245-121399896 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039457",
"HPA039801"
] | [
"APC5"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Supported | null | 67 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 47: Platelets - Hemostasis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,797 | 9 |
ENSG00000089060 | SLC8B1 | Solute carrier family 8 member B1 | [
"Q6J4K2"
] | 12 | 113298759-113359493 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040668"
] | [
"FLJ22233",
"NCKX6",
"NCLX",
"SLC24A6"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Calcium transport",
"Ion transport",
"Sensory transduction",
"Sodium transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,799 | 2 |
ENSG00000089063 | TMEM230 | Transmembrane protein 230 | [
"Q96A57"
] | 20 | 5068232-5113103 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA009078",
"HPA061421"
] | [
"C20orf30",
"HSPC274"
] | [
"Disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Disease variant",
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Uncertain | null | 7 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 28: Oligodendrocytes - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,800 | 7 |
ENSG00000089091 | DZANK1 | Double zinc ribbon and ankyrin repeat domains 1 | [
"Q9NVP4"
] | 20 | 18383367-18467281 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA059478"
] | [
"ANKRD64",
"bA189K21.8",
"C20orf12",
"C20orf84",
"dJ568F9.2",
"FLJ10600",
"FLJ30892"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 2 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 17: Choroid plexus - Cilium | Cluster 3: Rhabdoid - Membrane components | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 4 | 0 | 4 | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 1,801 | 4 |
ENSG00000089094 | KDM2B | Lysine demethylase 2B | [
"Q8NHM5"
] | 12 | 121429096-121581023 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071257"
] | [
"CXXC2",
"Fbl10",
"FBXL10",
"JHDM1B",
"PCCX2"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Chromatin regulator",
"Dioxygenase",
"DNA-binding",
"Oxidoreductase",
"Repressor",
"RNA-binding",
"rRNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 30 | null | null | Cluster 24: Non-specific - Transcription | Cluster 37: Neurons - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,802 | 7 |
ENSG00000089101 | CFAP61 | Cilia and flagella associated protein 61 | [
"Q8NHU2"
] | 20 | 20052514-20360703 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA009079"
] | [
"C20orf26",
"CaM-IP3",
"dJ1002M8.3",
"DKFZP434K156"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant"
] | [
"Cytosol",
"Principal piece"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 11: Neuronal - Sensory perception | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,803 | 6 |
ENSG00000089116 | LHX5 | LIM homeobox 5 | [
"Q9H2C1"
] | 12 | 113462033-113472280 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA053908"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | Approved | null | null | 17 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 109: Neurons - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Group enriched | Detected in some | 23 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,804 | 2 |
ENSG00000089123 | TASP1 | Taspase 1 | [
"Q9H6P5"
] | 20 | 13389392-13638932 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030824",
"HPA030825"
] | [
"C20orf13",
"dJ585I14.2",
"FLJ20212"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protease",
"Threonine protease"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Uncertain | null | null | No | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,805 | 7 |
ENSG00000089154 | GCN1 | GCN1 activator of EIF2AK4 | [
"Q92616"
] | 12 | 120127202-120194715 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018799",
"HPA019648",
"HPA024367"
] | [
"GCN1L",
"GCN1L1",
"KIAA0219"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Stress response",
"Translation regulation"
] | [
"Activator"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 42 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 6: Non-specific - Immune response | Cluster 38: Non-specific - Transcription | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,807 | 3 |
ENSG00000089157 | RPLP0 | Ribosomal protein lateral stalk subunit P0 | [
"P05388"
] | 12 | 120196699-120201235 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003512",
"HPA073501"
] | [
"L10E",
"LP0",
"P0",
"PRLP0",
"RPP0"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 375 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 44: Non-specific - Mixed function | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,808 | 6 |
ENSG00000089159 | PXN | Paxillin | [
"P49023"
] | 12 | 120210439-120265771 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003841",
"HPA051309"
] | [] | [
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Focal adhesion sites"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Enhanced | Supported | null | 89 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 5 | 0 | 5 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,809 | 6 |
ENSG00000089163 | SIRT4 | Sirtuin 4 | [
"Q9Y6E7"
] | 12 | 120302316-120313249 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029691",
"HPA029692"
] | [
"SIR2L4"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [
"DNA damage"
] | [
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [
"Cancer-related genes",
"Tumor suppressor"
] | [] | [] | [] | [] | null | Enhanced | null | 9 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 37: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,810 | 1 |
ENSG00000089169 | RPH3A | Rabphilin 3A | [
"Q9Y2J0"
] | 12 | 112570380-112898881 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002475"
] | [
"exophilin-1",
"KIAA0985",
"rabphilin"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 7 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in many | 5 | Group enriched | Detected in many | 5 | Cancer enriched | Detected in some | 7 | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 0 | 0 | 0 | [] | [] | [] | 1,811 | 5 |
ENSG00000089177 | KIF16B | Kinesin family member 16B | [
"Q96L93"
] | 20 | 16272104-16573448 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051198"
] | [
"C20orf23",
"dJ971B4.1",
"FLJ20135",
"SNX23"
] | [
"Predicted intracellular proteins"
] | [
"Transport"
] | [
"Motor protein"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Uncertain | Approved | null | null | null | null | Cluster 18: Non-specific - Translation | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Breast cancer - Unknown function | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 1,812 | 2 |
ENSG00000089195 | TRMT6 | TRNA methyltransferase 6 non-catalytic subunit | [
"Q9UJA5"
] | 20 | 5937228-5950558 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047032",
"HPA050408"
] | [
"CGI-09",
"GCD10",
"Gcd10p",
"MGC5029"
] | [
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cell Junctions"
] | [] | [] | Enhanced | Approved | null | 19 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 37: Neurons - Mixed function | Cluster 62: Non-specific - Plasma proteins | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,813 | 6 |
ENSG00000089220 | PEBP1 | Phosphatidylethanolamine binding protein 1 | [
"P30086"
] | 12 | 118136124-118145584 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008819",
"CAB009906",
"CAB013493",
"HPA063904",
"CAB080063"
] | [
"HCNP",
"PBP",
"PEBP",
"RKIP"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 20 | null | null | Cluster 18: Non-specific - Translation | Cluster 27: Non-specific - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,815 | 4 |
ENSG00000089225 | TBX5 | T-box transcription factor 5 | [
"Q99593"
] | 12 | 114353911-114408442 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008786",
"HPA064683"
] | [
"HOS"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Atrial fibrillation",
"Cardiomyopathy",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 7 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in single | 7 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,816 | 7 |
ENSG00000089234 | BRAP | BRCA1 associated protein | [
"Q7Z569"
] | 12 | 111642146-111685956 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040357",
"HPA058820"
] | [
"BRAP2",
"IMP",
"RNF52"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [
"Nuclear membrane"
] | [] | [] | Supported | Approved | null | 23 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,817 | 9 |
ENSG00000089248 | ERP29 | Endoplasmic reticulum protein 29 | [
"P30040"
] | 12 | 112013348-112023449 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039363",
"HPA039456"
] | [
"C12orf8",
"ERp28",
"ERp31",
"PDI-DB",
"PDIA9"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Microtubules"
] | [
"Nucleoplasm"
] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Uncertain | Enhanced | null | 26 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 44: Non-specific - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,818 | 8 |
ENSG00000089250 | NOS1 | Nitric oxide synthase 1 | [
"P29475"
] | 12 | 117208142-117452170 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002167",
"HPA058312",
"HPA069509"
] | [
"nNOS",
"NOS"
] | [
"Cancer-related genes",
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Calmodulin-binding",
"Oxidoreductase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 8 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,819 | 4 |
ENSG00000089280 | FUS | FUS RNA binding protein | [
"P35637"
] | 16 | 31180138-31191605 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008784",
"CAB033036",
"CAB058691"
] | [
"ALS6",
"FUS1",
"hnRNP-P2",
"HNRNPP2",
"TLS"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"RNA-binding"
] | [
"Amyotrophic lateral sclerosis",
"Cancer-related genes",
"Disease variant",
"Neurodegeneration",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 198 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 20: Non-specific - Transcription regulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,820 | 7 |
ENSG00000089327 | FXYD5 | FXYD domain containing ion transport regulator 5 | [
"Q96DB9"
] | 19 | 35154730-35169881 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA010817"
] | [
"OIT2"
] | [
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Sodium/potassium transport",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 69: Skin cancer - ECM organization | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma"
] | [
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,822 | 4 |
ENSG00000089335 | ZNF302 | Zinc finger protein 302 | [
"Q9NR11"
] | 19 | 34677639-34686397 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045896"
] | [
"ZNF135L",
"ZNF140L",
"ZNF327"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 5 | null | No | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,823 | 8 |
ENSG00000089351 | GRAMD1A | GRAM domain containing 1A | [
"Q96CP6"
] | 19 | 34994784-35026471 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008852",
"HPA012570"
] | [
"FLJ90346",
"KIAA1533"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Autophagy",
"Lipid transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 16 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 18: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,824 | 7 |
ENSG00000089356 | FXYD3 | FXYD domain containing ion transport regulator 3 | [
"Q14802"
] | 19 | 35115823-35124324 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010856"
] | [
"MAT-8",
"PLML"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Sodium/potassium transport",
"Transport"
] | [] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane"
] | [
"Intracellular and membrane"
] | [
"Transport"
] | Approved | Supported | null | 1 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,825 | 3 |
ENSG00000089472 | HEPH | Hephaestin | [
"Q9BQS7"
] | X | 66162671-66268867 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005824"
] | [
"CPL",
"KIAA0698"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Iron transport",
"Transport"
] | [
"Oxidoreductase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 1,826 | 9 |
ENSG00000089486 | CDIP1 | Cell death inducing p53 target 1 | [
"Q9H305"
] | 16 | 4510669-4538828 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049352"
] | [
"C16orf5",
"CDIP",
"LITAFL"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Centrosome"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 10 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 51: Myeloma - Immunoglobulins | Cluster 102: Non-specific - Mixed function | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 1,827 | 8 |
ENSG00000089505 | CMTM1 | CKLF like MARVEL transmembrane domain containing 1 | [
"Q8IZ96"
] | 16 | 66566393-66579137 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA013801",
"HPA017136"
] | [
"CKLFH",
"CKLFH1a",
"CKLFSF1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Chemotaxis"
] | [
"Cytokine"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 68: Non-specific - Cell cycle regulation | Cluster 22: Non-specific - Basic cellular functions | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in many | 10 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in many | 4 | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | 1,828 | 6 |
ENSG00000089558 | KCNH4 | Potassium voltage-gated channel subfamily H member 4 | [
"Q9UQ05"
] | 17 | 42156891-42181142 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [] | [
"elk1",
"Kv12.3"
] | [
"Predicted membrane proteins",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,829 | 6 |
ENSG00000089597 | GANAB | Glucosidase II alpha subunit | [
"Q14697"
] | 11 | 62624826-62646726 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026874",
"HPA061426"
] | [
"G2AN",
"GIIA",
"GluII",
"KIAA0088"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosidase",
"Hydrolase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Enhanced | null | 27 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 1,830 | 7 |
ENSG00000089639 | GMIP | GEM interacting protein | [
"Q9P107"
] | 19 | 19629476-19643657 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042484",
"HPA045481"
] | [
"ARHGAP46"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Enhanced | Enhanced | null | 2 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 46: Lymphoma - Humoral immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Squamous Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | 1,831 | 7 |
ENSG00000089682 | RBM41 | RNA binding motif protein 41 | [
"Q96IZ5"
] | X | 107061885-107118823 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042881"
] | [
"FLJ11016"
] | [
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Nuclear speckles",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 27 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 36: Non-specific - mRNA processing | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,832 | 1 |
ENSG00000089685 | BIRC5 | Baculoviral IAP repeat containing 5 | [
"O15392"
] | 17 | 78214186-78225636 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002830",
"CAB004270"
] | [
"API4",
"EPR-1",
"survivin"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Cell cycle",
"Cell division",
"Chromosome partition",
"Host-virus interaction",
"Mitosis",
"Transcription",
"Transcription regulation"
] | [
"Protease inhibitor",
"Repressor",
"Thiol protease inhibitor"
] | [
"Cancer-related genes"
] | [
"Cytokinetic bridge"
] | [] | [] | [] | Supported | Enhanced | null | 57 | Yes | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 11: White matter - Signal transduction | Cluster 27: Breast cancer - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 5 | 6 | 2 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 1,833 | 4 |
ENSG00000089692 | LAG3 | Lymphocyte activating 3 | [
"P18627"
] | 12 | 6772512-6778455 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002301",
"HPA013967"
] | [
"CD223"
] | [
"CD markers",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Immunity"
] | [] | [
"FDA approved drug targets"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Immunity"
] | null | Enhanced | null | 1 | null | null | Cluster 1: T-cells - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 1,834 | 6 |
ENSG00000089693 | MLF2 | Myeloid leukemia factor 2 | [
"Q15773"
] | 12 | 6747996-6767475 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010811",
"HPA010859"
] | [
"NTN4"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 41 | null | Yes | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 38: Non-specific - Transcription | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 1,835 | 3 |
ENSG00000089723 | OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 | [
"Q96DC9"
] | 14 | 94026340-94048930 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002329",
"HPA075090"
] | [
"C14orf137",
"FLJ21916",
"MGC3102"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 32 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 38: Sub-cortical - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 47: Testis - Mixed function | Group enriched | Detected in some | 4 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 34 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 1,836 | 2 |
ENSG00000089737 | DDX24 | DEAD-box helicase 24 | [
"Q9GZR7"
] | 14 | 94048287-94081202 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002554"
] | [] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nucleoli",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 138 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 15: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma"
] | 1,837 | 8 |
ENSG00000089775 | ZBTB25 | Zinc finger and BTB domain containing 25 | [
"P24278"
] | 14 | 64449106-64505213 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054699"
] | [
"C14orf51",
"KUP",
"ZNF46"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 35 | null | null | Cluster 11: T-cells - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Thyroid Carcinoma"
] | 1,838 | 1 |
ENSG00000089818 | NECAP1 | NECAP endocytosis associated 1 | [
"Q8NC96"
] | 12 | 8076939-8097881 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA053980",
"HPA063300"
] | [
"DKFZP566B183"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Protein transport",
"Transport"
] | [] | [
"Epilepsy"
] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 33 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 14: Neurons - Synaptic function | Cluster 38: Non-specific - Transcription | Cluster 105: Non-specific - Mixed function | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Chromophobe"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,839 | 7 |
ENSG00000089847 | ANKRD24 | Ankyrin repeat domain 24 | [
"Q8TF21"
] | 19 | 4182689-4224814 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA041534",
"HPA048498"
] | [
"KIAA1981"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Microtubules",
"Cytosol"
] | [] | [] | [] | Uncertain | Uncertain | null | 1 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,841 | 1 |
ENSG00000089902 | RCOR1 | REST corepressor 1 | [
"Q9UKL0"
] | 14 | 102592649-102730561 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001956",
"HPA049327",
"HPA054241"
] | [
"COREST",
"KIAA0071",
"RCOR"
] | [
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 100 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 35: Non-specific - DNA binding | Cluster 30: Non-specific - Gene expression regulation | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,843 | 6 |
ENSG00000089916 | GPATCH2L | G-patch domain containing 2 like | [
"Q9NWQ4"
] | 14 | 76151916-76254342 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018856"
] | [
"C14orf118",
"FLJ10033",
"FLJ20689"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 30 | null | null | Cluster 41: Basophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Chromophobe"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe"
] | 1,844 | 6 |
ENSG00000090006 | LTBP4 | Latent transforming growth factor beta binding protein 4 | [
"Q8N2S1"
] | 19 | 40592883-40629818 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB015194"
] | [
"FLJ46318",
"FLJ90018",
"LTBP-4",
"LTBP-4L"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Growth factor binding"
] | [
"Disease variant"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Other"
] | null | Enhanced | null | 6 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 24: Neurons - Mixed function | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,845 | 8 |
ENSG00000090013 | BLVRB | Biliverdin reductase B | [
"P30043"
] | 19 | 40447765-40465764 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041698",
"HPA041937"
] | [
"FLR",
"SDR43U1"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase",
"Transferase"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Vesicles",
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 9 | No | No | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 49: Hindbrain - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 84: Apical squamous epithelium - Cornification | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,846 | 1 |
ENSG00000090020 | SLC9A1 | Solute carrier family 9 member A1 | [
"P19634"
] | 1 | 27098809-27166981 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022371",
"HPA048532",
"HPA052891"
] | [
"APNH",
"NHE-1",
"NHE1",
"PPP1R143"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Ion transport",
"Sodium transport",
"Transport"
] | [
"Calmodulin-binding"
] | [
"Deafness",
"Disease variant",
"Neurodegeneration"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 20 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,847 | 6 |
ENSG00000090054 | SPTLC1 | Serine palmitoyltransferase long chain base subunit 1 | [
"O15269"
] | 9 | 92000087-92115413 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010860",
"CAB018747",
"HPA063907"
] | [
"hLCB1",
"HSAN1",
"HSN1",
"LCB1",
"SPTI"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Lipid metabolism",
"Sphingolipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [
"Amyotrophic lateral sclerosis",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Supported | null | 38 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 30: White matter - Myelination | Cluster 43: Non-specific - Basic cellular processes | Cluster 84: Apical squamous epithelium - Cornification | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,848 | 1 |
ENSG00000090060 | PAPOLA | Poly(A) polymerase alpha | [
"P51003"
] | 14 | 96501433-96567116 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001788"
] | [
"PAP"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"mRNA processing"
] | [
"RNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 4 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,849 | 1 |
ENSG00000090061 | CCNK | Cyclin K | [
"O75909"
] | 14 | 99481169-99535044 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000645",
"HPA077073"
] | [
"CPR4"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Host-virus interaction",
"Mitosis",
"Transcription",
"Transcription regulation"
] | [
"Cyclin"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 24 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,850 | 5 |
ENSG00000090097 | PCBP4 | Poly(rC) binding protein 4 | [
"P57723"
] | 3 | 51957454-51974016 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA057754"
] | [
"LIP4",
"MCG10"
] | [
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | null | null | 4 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 11: White matter - Signal transduction | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 1,851 | 2 |
ENSG00000090104 | RGS1 | Regulator of G protein signaling 1 | [
"Q08116"
] | 1 | 192575763-192580024 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA074572"
] | [
"1R20",
"BL34",
"IER1",
"IR20"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation",
"Signal transduction inhibitor"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 1,852 | 8 |
ENSG00000090238 | YPEL3 | Yippee like 3 | [
"P61236"
] | 16 | 30092314-30096915 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA030501",
"HPA045621"
] | [
"MGC10500"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 6 | 0 | 0 | 0 | [] | [] | [] | 1,853 | 6 |
ENSG00000090263 | MRPS33 | Mitochondrial ribosomal protein S33 | [
"Q9Y291"
] | 7 | 141002610-141015228 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030425"
] | [
"CGI-139"
] | [
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 45 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 39: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | 1,854 | 7 |
ENSG00000090266 | NDUFB2 | NADH:ubiquinone oxidoreductase subunit B2 | [
"O95178"
] | 7 | 140690777-140722790 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051377"
] | [
"AGGG",
"CI-AGGG"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Electron transport",
"Respiratory chain",
"Transport"
] | [] | [] | [
"Nucleoplasm"
] | [
"Mitochondria"
] | [] | [] | Uncertain | Approved | null | 1 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 39: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,855 | 3 |
ENSG00000090273 | NUDC | Nuclear distribution C, dynein complex regulator | [
"Q9Y266"
] | 1 | 26900238-26946871 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027183",
"HPA028105"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Uncertain | Enhanced | null | 60 | null | null | Cluster 41: Basophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 1,856 | 3 |
ENSG00000090316 | MAEA | Macrophage erythroblast attacher, E3 ubiquitin ligase | [
"Q7L5Y9"
] | 4 | 1289887-1340147 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036886",
"HPA058185"
] | [
"EMP",
"GID9",
"HLC-10",
"p44EMLP"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Erythrocyte maturation",
"Ubl conjugation pathway"
] | [
"Actin-binding",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 40 | Yes | No | Cluster 7: Non-specific - Innate immune response | Cluster 1: Neurons - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,857 | 9 |
ENSG00000090339 | ICAM1 | Intercellular adhesion molecule 1 | [
"P05362"
] | 19 | 10271093-10286615 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002126",
"CAB002142",
"HPA004877"
] | [
"BB2",
"CD54"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"CD markers",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Cell adhesion",
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 36 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 1,858 | 9 |
ENSG00000090372 | STRN4 | Striatin 4 | [
"Q9NRL3"
] | 19 | 46719511-46746994 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043051",
"HPA043527",
"HPA056706"
] | [
"PPP2R6C",
"ZIN"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Calmodulin-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Supported | null | 59 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 47: Platelets - Hemostasis | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 1,859 | 8 |
ENSG00000090376 | IRAK3 | Interleukin 1 receptor associated kinase 3 | [
"Q9Y616"
] | 12 | 66189195-66254622 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043097"
] | [
"IRAK-M"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [] | [
"Asthma"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 47: Endothelial cells - Vasculature | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,860 | 5 |
ENSG00000090382 | LYZ | Lysozyme | [
"P61626"
] | 12 | 69348381-69354234 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000055",
"HPA048284",
"HPA066182"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted secreted proteins"
] | [] | [
"Antimicrobial",
"Bacteriolytic enzyme",
"Glycosidase",
"Hydrolase"
] | [
"Amyloidosis",
"Disease variant"
] | [
"Golgi apparatus",
"Actin filaments"
] | [
"Nucleoplasm"
] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Enhanced | null | 14 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 12: Non-specific - Vasculature | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 4 | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | 1,861 | 7 |
ENSG00000090402 | SI | Sucrase-isomaltase | [
"P14410"
] | 3 | 164978898-165078496 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011897"
] | [] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosidase",
"Hydrolase",
"Multifunctional enzyme"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | null | Cluster 10: Ciliated cells - Ion channel activity | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in some | 150 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,862 | 2 |
ENSG00000090432 | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1 | [
"Q969V5"
] | 1 | 20499448-20508151 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026827"
] | [
"C1orf166",
"FLJ12875",
"GIDE",
"MAPL",
"MULAN",
"RNF218"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Approved | null | null | 20 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 45: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 1,863 | 5 |
ENSG00000090447 | TFAP4 | Transcription factor AP-4 | [
"Q01664"
] | 16 | 4257186-4273075 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001912"
] | [
"AP-4",
"bHLHc41"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | [] | Approved | Supported | null | 36 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 37: Neurons - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 1,864 | 4 |
ENSG00000090470 | PDCD7 | Programmed cell death 7 | [
"Q8N8D1"
] | 15 | 65117379-65133808 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049388"
] | [
"59K",
"ES18",
"HES18"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Plasma membrane"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 6 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 48: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 1,865 | 9 |
ENSG00000090487 | SPG21 | SPG21 abhydrolase domain containing, maspardin | [
"Q9NZD8"
] | 15 | 64963022-64990310 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040407",
"HPA040436"
] | [
"ABHD21",
"ACP33",
"BM-019",
"GL010",
"MAST"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 151 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 21: Non-specific - Metabolism | Cluster 58: Non-specific - Nuclear processes | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,866 | 9 |
ENSG00000090512 | FETUB | Fetuin B | [
"Q9UGM5"
] | 3 | 186635969-186653141 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035132",
"HPA035133"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Fertilization"
] | [
"Metalloenzyme inhibitor",
"Metalloprotease inhibitor",
"Protease inhibitor"
] | [] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Enzyme inhibitor"
] | Approved | Supported | null | 6 | null | null | null | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 27 | Not detected | Not detected | null | Cancer enriched | Detected in some | 6 | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,867 | 7 |
ENSG00000090520 | DNAJB11 | DnaJ heat shock protein family (Hsp40) member B11 | [
"Q9UBS4"
] | 3 | 186567403-186585800 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010814",
"HPA017051"
] | [
"EDJ",
"ERdj3",
"HEDJ"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | Supported | Supported | null | 85 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 65: Non-specific - Cell growth & division | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | 1,868 | 1 |
ENSG00000090534 | THPO | Thrombopoietin | [
"P40225"
] | 3 | 184371935-184381968 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MGDF",
"MPLLG",
"TPO"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [] | [
"Cytokine",
"Hormone"
] | [
"Cancer-related genes",
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Cytokine"
] | null | null | null | null | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,870 | 4 |
ENSG00000090539 | CHRD | Chordin | [
"Q9H2X0"
] | 3 | 184380054-184390736 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035827"
] | [] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Developmental protein"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Developmental protein"
] | null | Approved | null | 45 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 1,871 | 8 |
ENSG00000090554 | FLT3LG | Fms related receptor tyrosine kinase 3 ligand | [
"P49771"
] | 19 | 49474207-49486231 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Cytokine"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Cytokine"
] | null | null | null | 1 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 43: Hindbrain - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 5 | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 1,872 | 1 |
ENSG00000090565 | RAB11FIP3 | RAB11 family interacting protein 3 | [
"O75154"
] | 16 | 425649-523011 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028088",
"HPA028631",
"HPA030086"
] | [
"eferin",
"KIAA0665",
"Rab11-FIP3"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Transport"
] | [] | [
"Cancer-related genes"
] | [
"Vesicles",
"Centriolar satellite",
"Basal body"
] | [
"Cytokinetic bridge",
"Primary cilium"
] | [] | [] | Supported | Enhanced | null | 8 | Yes | No | null | Cluster 32: Cerebral cortex - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 7 | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,873 | 7 |
ENSG00000090612 | ZNF268 | Zinc finger protein 268 | [
"Q14587"
] | 12 | 133181409-133214832 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001794"
] | [
"HZF3"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 5: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,875 | 4 |
ENSG00000090615 | GOLGA3 | Golgin A3 | [
"Q08378"
] | 12 | 132768902-132829143 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039809",
"HPA040044"
] | [
"GCP170",
"golgin-160",
"MEA-2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 9 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 32: Cerebral cortex - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 1,876 | 8 |
ENSG00000090621 | PABPC4 | Poly(A) binding protein cytoplasmic 4 | [
"Q13310"
] | 1 | 39560709-39576790 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027301",
"HPA056496"
] | [
"APP-1",
"iPABP"
] | [
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | 101 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 12: Non-specific - Vasculature | Cluster 37: Non-specific - mRNA processing | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,877 | 9 |
ENSG00000090659 | CD209 | CD209 molecule | [
"Q9NNX6"
] | 19 | 7739993-7747564 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB032436",
"CAB033831"
] | [
"CDSIGN",
"CLEC4L",
"DC-SIGN",
"DC-SIGN1",
"hDC-SIGN"
] | [
"CD markers",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Adaptive immunity",
"Cell adhesion",
"Endocytosis",
"Host-virus interaction",
"Immunity",
"Innate immunity"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | null | Supported | null | 6 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in single | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 5 | 0 | 0 | 0 | [] | [] | [] | 1,878 | 8 |
ENSG00000090674 | MCOLN1 | Mucolipin TRP cation channel 1 | [
"Q9GZU1"
] | 19 | 7522624-7534009 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031763",
"CAB032637"
] | [
"ML4",
"MLIV",
"MST080",
"MSTP080",
"TRPM-L1",
"TRPML1"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Adaptive immunity",
"Calcium transport",
"Immunity",
"Ion transport",
"Transport"
] | [
"Ion channel"
] | [
"Corneal dystrophy",
"Disease variant",
"Mucolipidosis"
] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 7 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 4 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 1,880 | 2 |
ENSG00000090686 | USP48 | Ubiquitin specific peptidase 48 | [
"Q86UV5"
] | 1 | 21678298-21783606 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030045",
"HPA030046"
] | [
"FLJ11328",
"FLJ20103",
"FLJ23054",
"FLJ23277",
"MGC14879",
"USP31"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Deafness",
"Non-syndromic deafness"
] | [
"Nucleoplasm"
] | [
"Mitochondria",
"Cytosol"
] | [] | [] | Supported | Approved | null | 49 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,881 | 3 |
ENSG00000090857 | PDPR | Pyruvate dehydrogenase phosphatase regulatory subunit | [
"Q8NCN5"
] | 16 | 70114332-70162537 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048092",
"HPA070386"
] | [
"PDP3"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | 5 | null | null | Cluster 32: Basophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 11: Neuronal - Sensory perception | Cluster 7: Non-specific - Transcription | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 1,883 | 9 |
ENSG00000090861 | AARS1 | Alanyl-tRNA synthetase 1 | [
"P49588"
] | 16 | 70251983-70289707 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034261",
"HPA040870",
"HPA044223"
] | [
"AARS",
"AlaRS",
"CMT2N"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase",
"RNA-binding",
"tRNA-binding"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Epilepsy",
"Neurodegeneration",
"Neuropathy"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 5 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 45: Non-specific - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 65: Non-specific - Cell growth & division | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 1,884 | 2 |
ENSG00000090863 | GLG1 | Golgi glycoprotein 1 | [
"Q92896"
] | 16 | 74447427-74607144 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010815"
] | [
"CFR-1",
"ESL-1",
"MG-160"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Supported | Supported | null | 13 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 27: Non-specific - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 1,885 | 2 |
ENSG00000090889 | KIF4A | Kinesin family member 4A | [
"O95239"
] | X | 70290104-70420886 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034745",
"HPA034746",
"HPA061583"
] | [
"FLJ12530",
"FLJ12655",
"FLJ14204",
"FLJ20631",
"HSA271784",
"KIF4",
"KIF4-G1",
"MRX100"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding",
"Motor protein"
] | [
"Intellectual disability"
] | [
"Nucleoplasm",
"Midbody"
] | [
"Acrosome",
"Equatorial segment",
"Mid piece",
"Principal piece"
] | [] | [] | Approved | Approved | null | 15 | Yes | Yes | Cluster 9: T-regs - Cell cycle regulation | Cluster 46: Brainstem - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 6 | 2 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 1,886 | 9 |
ENSG00000090905 | TNRC6A | Trinucleotide repeat containing adaptor 6A | [
"Q8NDV7"
] | 16 | 24610209-24827632 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015305",
"HPA017869"
] | [
"CAGH26",
"GW182",
"KIAA1460",
"TNRC6"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"RNA-mediated gene silencing",
"Translation regulation"
] | [
"RNA-binding"
] | [
"Epilepsy"
] | [
"Nucleoplasm",
"Golgi apparatus",
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 57 | null | null | Cluster 32: Basophils - Transcription | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 54: Non-specific - Transcription | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 1,887 | 2 |
ENSG00000090924 | PLEKHG2 | Pleckstrin homology and RhoGEF domain containing G2 | [
"Q9H7P9"
] | 19 | 39412669-39428415 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017973",
"HPA048054"
] | [
"ARHGEF42",
"CLG",
"FLJ00018"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Disease variant",
"Intellectual disability",
"Leukodystrophy",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 7 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 12: Non-specific - Vasculature | Cluster 4: Non-specific - Transcription | Cluster 20: Non-specific - Transcription regulation | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 1,888 | 2 |
ENSG00000090932 | DLL3 | Delta like canonical Notch ligand 3 | [
"Q9NYJ7"
] | 19 | 39498895-39508481 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024559",
"HPA056533"
] | [
"SCDO1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Differentiation",
"Notch signaling pathway"
] | [
"Developmental protein"
] | [
"Disease variant",
"Dwarfism"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | Approved | null | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 51: Neurons - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 14: Oligodendrocyte progenitor cells - Development & myelination | Cluster 73: Brain - Neuronal signaling | Tissue enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Glioblastoma Multiforme",
"Uterine Corpus Endometrial Carcinoma"
] | 1,889 | 7 |
ENSG00000090971 | NAT14 | N-acetyltransferase 14 (putative) | [
"Q8WUY8"
] | 19 | 55485188-55487568 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047187"
] | [
"KLP1"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Acyltransferase",
"DNA-binding",
"Transferase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | null | null | 8 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 4: Non-specific - Transcription | Cluster 109: Neurons - Neuronal signaling | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 1,890 | 8 |
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