ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000095321
CRAT
Carnitine O-acetyltransferase
[ "P43155" ]
9
129094142-129111189
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019230", "HPA020260", "HPA022815" ]
[ "CAT1" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Fatty acid metabolism", "Lipid metabolism", "Transport" ]
[ "Acyltransferase", "Transferase" ]
[ "Neurodegeneration" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
1
null
null
Cluster 33: Non-specific - ATP binding
Cluster 45: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
2,008
4
ENSG00000095370
SH2D3C
SH2 domain containing 3C
[ "Q8N5H7" ]
9
127738317-127778710
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047586" ]
[ "NSP3" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
7
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 32: Cerebral cortex - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 5: Spleen - Immune response
Low tissue specificity
Detected in many
null
Group enriched
Detected in many
13
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
2,009
7
ENSG00000095380
NANS
N-acetylneuraminate synthase
[ "Q9NR45" ]
9
98056732-98083077
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019223" ]
[ "SAS" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[ "Disease variant", "Dwarfism", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
9
No
No
Cluster 10: Non-specific - Membrane trafficking
Cluster 21: Non-specific - Metabolism
Cluster 27: Breast cancer - Unknown function
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 60: Stomach - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[]
[ "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
2,010
6
ENSG00000095383
TBC1D2
TBC1 domain family member 2
[ "Q9BYX2" ]
9
98199011-98255649
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030871", "HPA076521" ]
[ "Armus", "PARIS1", "TBC1D2A" ]
[ "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
2
null
Yes
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 11: White matter - Signal transduction
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
0
3
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Testicular Germ Cell Tumor" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Testicular Germ Cell Tumor" ]
2,011
2
ENSG00000095397
WHRN
Whirlin
[ "Q9P202" ]
9
114402080-114505473
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB080582" ]
[ "CIP98", "DFNB31", "PDZD7B", "USH2D" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Hearing" ]
[]
[ "Deafness", "Non-syndromic deafness", "Retinitis pigmentosa", "Usher syndrome" ]
[]
[]
[]
[]
null
Approved
null
9
null
null
null
Cluster 28: Oligodendrocytes - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
2,012
3
ENSG00000095485
CWF19L1
CWF19 like cell cycle control factor 1
[ "Q69YN2" ]
10
100232298-100267680
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036889", "HPA036890" ]
[ "FLJ10998", "hDrn1" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Neurodegeneration" ]
[ "Nucleoplasm", "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
11
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 55: Non-specific - Transcription
Cluster 52: Non-specific - Mitochondria
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
2,014
2
ENSG00000095539
SEMA4G
Semaphorin 4G
[ "Q9NTN9" ]
10
100969504-100985871
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038362", "HPA077752" ]
[ "FLJ20590", "KIAA1619" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Differentiation", "Neurogenesis" ]
[ "Developmental protein" ]
[]
[ "Vesicles", "Lipid droplets" ]
[]
[ "Intracellular and membrane" ]
[ "Developmental protein" ]
Uncertain
Uncertain
null
4
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
2,015
5
ENSG00000095564
BTAF1
B-TFIID TATA-box binding protein associated factor 1
[ "O14981" ]
10
91923770-92031437
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA070682" ]
[ "MOT1", "TAF-172", "TAF(II)170", "TAF172", "TAFII170" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "DNA-binding", "Helicase", "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
null
null
21
null
null
Cluster 32: Basophils - Transcription
Cluster 55: Non-specific - Transcription
Cluster 56: Non-specific - Sensory perception
Cluster 103: Non-specific - Basic cellular processes
Cluster 58: Skin - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
2,016
9
ENSG00000095574
IKZF5
IKAROS family zinc finger 5
[ "Q9H5V7" ]
10
122990807-123008812
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015297", "HPA051574" ]
[ "FLJ22973", "Pegasus", "ZNFN1A5" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
Supported
null
null
9
null
null
Cluster 11: T-cells - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
2,017
8
ENSG00000095585
BLNK
B cell linker
[ "Q8WV28" ]
10
96189171-96271587
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009333", "CAB016291", "HPA038309", "HPA038310" ]
[ "BASH", "bca", "BLNK-s", "Ly57", "SLP-65", "SLP65" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "B-cell activation" ]
[]
[]
[ "Plasma membrane" ]
[ "Vesicles" ]
[]
[]
Supported
Enhanced
null
20
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 55: Lymphoma - Immune response
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 34: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
9
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,018
3
ENSG00000095587
TLL2
Tolloid like 2
[ "Q9Y6L7" ]
10
96364608-96513926
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Predicted secreted proteins" ]
[ "Differentiation" ]
[ "Developmental protein", "Hydrolase", "Metalloprotease", "Protease" ]
[]
[]
[]
[ "Secreted - unknown location" ]
[ "Developmental protein" ]
null
null
null
8
null
null
null
Cluster 49: Hindbrain - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 52: Non-specific - Cellular respiration
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,019
7
ENSG00000095596
CYP26A1
Cytochrome P450 family 26 subfamily A member 1
[ "O43174" ]
10
93073475-93077885
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CP26", "CYP26", "P450RAI", "P450RAI1" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid metabolism" ]
[ "Monooxygenase", "Oxidoreductase" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 14: Neurons - Synaptic function
Cluster 3: Rhabdoid - Membrane components
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in single
27
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,020
5
ENSG00000095627
TDRD1
Tudor domain containing 1
[ "Q9BXT4" ]
10
114179270-114232666
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037729" ]
[ "CT41.1" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Differentiation", "Meiosis", "RNA-mediated gene silencing", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 48: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in some
9
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in some
5
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
2,021
6
ENSG00000095739
BAMBI
BMP and activin membrane bound inhibitor
[ "Q13145" ]
10
28677510-28682932
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA010819", "HPA010866" ]
[ "NMA" ]
[ "Plasma proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Nucleoli fibrillar center", "Lipid droplets" ]
[]
[]
Approved
Approved
null
2
null
null
null
Cluster 30: White matter - Myelination
Cluster 32: Non-specific - Cell proliferation
Cluster 108: Fibroblasts - ECM organization
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,024
4
ENSG00000095777
MYO3A
Myosin IIIA
[ "Q8NEV4" ]
10
25934229-26212532
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051893", "HPA075413" ]
[ "DFNB30" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Hearing", "Sensory transduction", "Vision" ]
[ "Actin-binding", "Kinase", "Motor protein", "Myosin", "Serine/threonine-protein kinase", "Transferase" ]
[ "Deafness", "Disease variant", "Non-syndromic deafness" ]
[ "Actin filaments", "Cytoplasmic bodies" ]
[ "Plasma membrane" ]
[]
[]
Supported
Enhanced
null
1
No
No
null
Cluster 33: Neurons - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 42: Retina - Visual perception
Group enriched
Detected in some
6
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
2,026
6
ENSG00000095787
WAC
WW domain containing adaptor with coiled-coil
[ "Q9BTA9" ]
10
28532493-28623112
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036528", "HPA042609", "HPA074604" ]
[ "BM-016", "FLJ31290", "MGC10753", "PRO1741", "Wwp4" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Chromatin regulator" ]
[]
[ "Nucleoplasm" ]
[ "Centrosome" ]
[]
[]
Enhanced
Approved
null
25
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 16: Non-specific - Transcription
Cluster 52: Non-specific - Mitochondria
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,027
1
ENSG00000095794
CREM
CAMP responsive element modulator
[ "Q03060" ]
10
35126791-35212958
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001818", "CAB018352" ]
[ "hCREM-2" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Biological rhythms", "Differentiation", "Spermatogenesis", "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
Enhanced
null
5
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 21: Non-specific - Metabolism
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,028
9
ENSG00000095906
NUBP2
NUBP iron-sulfur cluster assembly factor 2, cytosolic
[ "Q9Y5Y2" ]
16
1782932-1789186
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041704" ]
[ "CFD1", "CIAO6" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
39
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 42: Choroid plexus - Mitochondria
Cluster 54: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
2,029
7
ENSG00000095917
TPSD1
Tryptase delta 1
[ "Q9BZJ3" ]
16
1256059-1259008
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "CAB002215", "CAB032871", "HPA040182", "HPA049554" ]
[]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Supported
null
null
null
null
Cluster 46: Basophils - Proteolysis
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 49: HMC-1 - Innate immune response
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in single
44
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in some
29
Immune cell enriched
Detected in single
29
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,030
7
ENSG00000095932
SMIM24
Small integral membrane protein 24
[ "O75264" ]
19
3473986-3480525
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA045046", "HPA056027" ]
[ "C19orf77", "HSPC323" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 15: NK-cells - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 22: Epididymis - Mixed function
Group enriched
Detected in many
7
Group enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
5
Immune cell enhanced
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,031
9
ENSG00000095951
HIVEP1
HIVEP zinc finger 1
[ "P15822" ]
6
12008762-12164999
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050724", "HPA067457" ]
[ "CIRIP", "CRYBP1", "MBP-1", "PRDII-BF1", "Schnurri-1", "ZAS1", "ZNF40", "ZNF40A" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies", "Mitochondria", "Cytosol" ]
[]
[]
Supported
Approved
null
37
null
null
Cluster 30: Non-specific - DNA binding
Cluster 32: Cerebral cortex - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,032
9
ENSG00000095970
TREM2
Triggering receptor expressed on myeloid cells 2
[ "Q9NZC2" ]
6
41158506-41163186
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA010917", "HPA012571" ]
[ "TREM-2", "Trem2a", "Trem2b", "Trem2c" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Predicted secreted proteins", "Transporters" ]
[]
[ "Receptor" ]
[ "Alzheimer disease", "Amyloidosis", "Disease variant", "Neurodegeneration" ]
[ "Vesicles" ]
[]
[ "Secreted in brain" ]
[ "Receptor" ]
Uncertain
Approved
null
3
null
null
null
Cluster 20: Macrophages & Microglia - Immune response
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in some
6
Immune cell enhanced
Detected in single
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,033
7
ENSG00000095981
KCNK16
Potassium two pore domain channel subfamily K member 16
[ "Q96T55" ]
6
39314698-39322968
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "K2p16.1", "TALK-1", "TALK1" ]
[ "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Potassium channel", "Voltage-gated channel" ]
[]
[]
[]
[]
[]
null
null
null
1
null
null
null
null
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 8: Pancreas - Proteolysis
Group enriched
Detected in some
5
Cancer enriched
Detected in some
5
Cancer enriched
Detected in some
16
Cell type enriched
Detected in some
17
Immune cell enriched
Detected in single
10
0
0
0
[]
[]
[]
2,034
9
ENSG00000096006
CRISP3
Cysteine rich secretory protein 3
[ "P54108" ]
6
49727376-49744437
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054392" ]
[ "Aeg2", "CRISP-3", "CRS3", "dJ442L6.3", "SGP28" ]
[ "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "No annotated function" ]
null
Supported
null
1
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
null
Cluster 27: Breast cancer - Unknown function
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 82: Salivary gland - Secretion
Group enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Cell type enhanced
Detected in some
null
Group enriched
Detected in some
19
0
0
0
[]
[]
[]
2,035
7
ENSG00000096060
FKBP5
FKBP prolyl isomerase 5
[ "Q13451" ]
6
35573585-35728583
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009315", "HPA031092", "HPA031093", "HPA031095" ]
[ "FKBP51", "FKBP54", "P54", "PPIase", "Ptg-10" ]
[ "Cancer-related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Chaperone", "Isomerase", "Rotamase" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Nucleoli fibrillar center", "Cytosol" ]
[]
[]
Approved
Enhanced
null
329
No
No
Cluster 33: Non-specific - ATP binding
Cluster 19: Astrocytes - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
2,036
8
ENSG00000096063
SRPK1
SRSF protein kinase 1
[ "Q96SB4" ]
6
35832966-35921342
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016431", "HPA056486" ]
[ "SFRSK1" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Chromosome partition", "Differentiation", "Host-virus interaction", "mRNA processing", "mRNA splicing" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Supported
Approved
null
155
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 53: Neurons - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in all
null
6
2
5
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
2,037
5
ENSG00000096070
BRPF3
Bromodomain and PHD finger containing 3
[ "Q9ULD4" ]
6
36196744-36232790
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA022787" ]
[ "KIAA1286" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Chromatin regulator" ]
[]
[ "Nucleoplasm" ]
[ "Mitochondria" ]
[]
[]
Approved
Uncertain
null
16
No
No
Cluster 42: Non-specific - Vesicular transport
Cluster 34: Non-specific - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,038
8
ENSG00000096080
MRPS18A
Mitochondrial ribosomal protein S18A
[ "Q9NVS2" ]
6
43671202-43687791
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035450", "HPA035451" ]
[ "FLJ10548", "MRPS18-3" ]
[ "Essential proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[]
[]
[]
[]
null
Approved
null
71
null
null
Cluster 22: Eosinophils - Transcription
Cluster 21: Non-specific - Metabolism
Cluster 28: Non-specific - Nuclear processes
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,039
4
ENSG00000096088
PGC
Progastricsin
[ "P20142" ]
6
41736711-41754109
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031717", "HPA031718" ]
[]
[ "Cancer-related genes", "Enzymes", "Predicted intracellular proteins", "Predicted secreted proteins", "Transporters" ]
[ "Digestion" ]
[ "Aspartyl protease", "Hydrolase", "Protease" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[]
[ "Secreted to digestive system" ]
[ "Enzyme" ]
Approved
Enhanced
null
null
null
null
null
Cluster 2: Neurons - Nucleosome
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 97: Non-specific - Cellular respiration
Cluster 60: Stomach - Digestion
Tissue enriched
Detected in many
46
Cancer enriched
Detected in some
13
Group enriched
Detected in many
5
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,040
5
ENSG00000096092
TMEM14A
Transmembrane protein 14A
[ "Q9Y6G1" ]
6
52671113-52686588
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA072536" ]
[ "C6orf73", "PTD011" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Apoptosis" ]
[]
[]
[ "Nucleoplasm", "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Approved
null
21
null
null
Cluster 31: T-cells - T-cell receptor
Cluster 23: Choroid plexus - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 97: Non-specific - Cellular respiration
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,041
9
ENSG00000096093
EFHC1
EF-hand domain containing 1
[ "Q5JVL4" ]
6
52362123-52529886
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035307" ]
[ "EJM", "EJM1", "FLJ10466", "POC9", "RIB72" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Epilepsy" ]
[ "Plasma membrane", "Mid piece", "Principal piece", "End piece" ]
[ "Cytosol", "Equatorial segment" ]
[]
[]
Uncertain
Approved
null
64
null
null
Cluster 14: Non-specific - Unknown function
Cluster 17: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
2,042
2
ENSG00000096264
NCR2
Natural cytotoxicity triggering receptor 2
[ "O95944" ]
6
41335608-41350889
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA067249" ]
[ "CD336", "LY95", "NK-p44" ]
[ "CD markers", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 45: Non-specific - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
null
Not detected
Not detected
null
Group enriched
Detected in some
23
Not detected
Not detected
null
Group enriched
Detected in some
5
Group enriched
Detected in some
17
0
0
0
[]
[]
[]
2,043
3
ENSG00000096384
HSP90AB1
Heat shock protein 90 alpha family class B member 1
[ "P08238" ]
6
44246166-44253888
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005230", "HPA072606", "HPA074351" ]
[ "HSPC2", "HSPCB" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Stress response" ]
[ "Chaperone" ]
[ "Cancer-related genes" ]
[ "Plasma membrane" ]
[ "Cytosol" ]
[ "Intracellular and membrane" ]
[ "Other" ]
Supported
Enhanced
null
439
null
Yes
Cluster 43: Non-specific - Transcription & Translation
Cluster 27: Non-specific - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 75: Non-specific - Chaperones and protein folding
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,044
9
ENSG00000096395
MLN
Motilin
[ "P12872" ]
6
33794673-33804003
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA069392", "HPA077622" ]
[]
[ "Predicted secreted proteins" ]
[]
[ "Hormone" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
null
Enhanced
null
2
null
null
null
Cluster 30: White matter - Myelination
Cluster 72: Neuronal - Signal transduction
Cluster 96: Enteroendocrine cells - Neuropeptide signaling
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in single
410
Low cancer specificity
Detected in some
null
Group enriched
Detected in some
6
Cell type enriched
Detected in some
713
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,045
2
ENSG00000096401
CDC5L
Cell division cycle 5 like
[ "Q99459" ]
6
44387706-44450425
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006302", "HPA011361", "CAB012275" ]
[ "CDC5", "CEF1", "hCDC5", "PCDC5RP" ]
[ "Disease related genes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Cell cycle", "DNA damage", "DNA repair", "mRNA processing", "mRNA splicing", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
267
null
null
Cluster 25: Non-specific - Unknown function
Cluster 31: Non-specific - Transcription
Cluster 28: Non-specific - Nuclear processes
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
2,046
5
ENSG00000096433
ITPR3
Inositol 1,4,5-trisphosphate receptor type 3
[ "Q14573" ]
6
33620365-33696574
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003915", "HPA064704" ]
[ "IP3R3" ]
[ "Human disease related genes", "Plasma proteins", "Predicted membrane proteins" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Ion channel", "Ligand-gated ion channel", "Receptor" ]
[ "Charcot-Marie-Tooth disease", "Disease variant", "Neurodegeneration", "Neuropathy" ]
[ "Vesicles" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
37
No
Yes
Cluster 16: Non-specific - Cell proliferation
Cluster 47: Endothelial cells - Vasculature
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 68: Foveolar cells - Mucosal defense
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,047
7
ENSG00000096654
ZNF184
Zinc finger protein 184
[ "Q99676" ]
6
27450743-27473118
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003226", "HPA064793" ]
[]
[ "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Uncertain
null
4
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 53: Neurons - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 103: Non-specific - Basic cellular processes
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,048
9
ENSG00000096696
DSP
Desmoplakin
[ "P15924" ]
6
7541617-7586714
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037324", "HPA045840", "HPA054950" ]
[ "DPI", "DPII", "KPPS2", "PPKS2" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[]
[]
[ "Cardiomyopathy", "Disease variant", "Epidermolysis bullosa", "Palmoplantar keratoderma" ]
[ "Cell Junctions" ]
[]
[]
[]
Supported
Enhanced
null
45
null
null
Cluster 34: B-cells - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
16
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,049
9
ENSG00000096717
SIRT1
Sirtuin 1
[ "Q96EB6" ]
10
67884656-67918390
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB003855", "HPA006295", "HPA052351" ]
[ "SIR2L1" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Biological rhythms", "Differentiation", "Host-virus interaction", "Myogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli fibrillar center", "Mitochondria", "Cytosol" ]
[]
[]
Supported
Approved
null
225
null
null
Cluster 41: Basophils - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 52: Non-specific - Mitochondria
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
2,050
2
ENSG00000096746
HNRNPH3
Heterogeneous nuclear ribonucleoprotein H3
[ "P31942" ]
10
68331174-68343193
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038264" ]
[ "2H9", "HNRPH3" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing" ]
[ "Ribonucleoprotein", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
36
null
null
Cluster 33: Non-specific - ATP binding
Cluster 13: Oligodendrocytes - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 17: Non-specific - RNA processing
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,051
1
ENSG00000096872
IFT74
Intraflagellar transport 74
[ "Q96LB3" ]
9
26947039-27066134
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020247", "HPA026684" ]
[ "CCDC2", "CMG-1", "CMG1", "FLJ22621" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Cilium biogenesis/degradation" ]
[ "Developmental protein" ]
[ "Bardet-Biedl syndrome", "Ciliopathy", "Disease variant", "Joubert syndrome", "Obesity" ]
[ "Golgi apparatus", "Centriolar satellite", "Basal body" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
50
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 3: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
2,052
4
ENSG00000096968
JAK2
Janus kinase 2
[ "O60674" ]
9
4984390-5129948
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB013089", "HPA040820", "HPA043870" ]
[ "JTK10" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Adaptive immunity", "Immunity", "Innate immunity" ]
[ "Chromatin regulator", "Kinase", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Plasma membrane", "Focal adhesion sites" ]
[]
[]
Supported
Approved
null
44
No
No
Cluster 46: Basophils - Proteolysis
Cluster 53: Neurons - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,053
8
ENSG00000096996
IL12RB1
Interleukin 12 receptor subunit beta 1
[ "P42701" ]
19
18058995-18098944
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA074414" ]
[ "CD212", "IL12RB" ]
[ "CD markers", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[ "Disease variant" ]
[ "Plasma membrane" ]
[]
[ "Intracellular and membrane" ]
[ "Receptor" ]
Approved
null
null
null
null
null
Cluster 33: Non-specific - ATP binding
Cluster 11: White matter - Signal transduction
Cluster 51: Myeloma - Immunoglobulins
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 18: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
14
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Head and Neck Squamous Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma" ]
2,054
2
ENSG00000097007
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase
[ "P00519" ]
9
130713043-130887675
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002686", "HPA027251", "HPA027280", "HPA028409" ]
[ "ABL", "c-ABL", "JTK7", "p150" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[ "Apoptosis", "Autophagy", "Cell adhesion", "DNA damage", "DNA repair", "Endocytosis" ]
[ "DNA-binding", "Kinase", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Supported
Supported
null
162
Yes
No
Cluster 30: Non-specific - DNA binding
Cluster 6: Non-specific - Immune response
Cluster 43: Non-specific - Basic cellular processes
Cluster 103: Non-specific - Basic cellular processes
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,055
1
ENSG00000097021
ACOT7
Acyl-CoA thioesterase 7
[ "O00154" ]
1
6264269-6393767
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA025735", "HPA025762" ]
[ "ACH1", "ACT", "BACH", "CTE-II", "hBACH", "LACH1", "MGC1126" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Fatty acid metabolism", "Lipid metabolism" ]
[ "Hydrolase", "Serine esterase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
13
No
No
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 1: Neurons - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 10: Brain - Synaptic signal transduction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Group enriched
Detected in many
5
2
2
1
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,056
4
ENSG00000097033
SH3GLB1
SH3 domain containing GRB2 like, endophilin B1
[ "Q9Y371" ]
1
86704570-86748184
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004650", "HPA015608", "HPA019900" ]
[ "Bif-1", "CGI-61", "KIAA0491", "PPP1R70" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Apoptosis", "Autophagy" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
129
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 55: Non-specific - Transcription
Cluster 37: Non-specific - mRNA processing
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,057
5
ENSG00000097046
CDC7
Cell division cycle 7
[ "O00311" ]
1
91500851-91525764
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002669", "HPA035831" ]
[ "CDC7L1", "HsCdc7", "Hsk1", "huCdc7" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Cytokinetic bridge", "Mitotic spindle" ]
[]
[]
Supported
Enhanced
null
55
Yes
No
Cluster 30: Non-specific - DNA binding
Cluster 2: Neurons - Nucleosome
Cluster 37: Non-specific - mRNA processing
Cluster 4: Breast lactating luminal cells - Lactation
Cluster 32: Retina & Lymphoid tissues - Signaling
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in all
7
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in many
null
4
0
4
[ "Lung Squamous Cell Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
2,058
3
ENSG00000097096
SYDE2
Synapse defective Rho GTPase homolog 2
[ "Q5VT97" ]
1
85156889-85201724
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027138", "HPA058378" ]
[ "FLJ13815" ]
[ "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Nucleoli", "Nucleoli rim", "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
13
No
No
null
Cluster 29: Forebrain - Mixed function
Cluster 34: Testis cancer - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
2,059
6
ENSG00000099139
PCSK5
Proprotein convertase subtilisin/kexin type 5
[ "Q92824" ]
9
75890644-76362975
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031072" ]
[ "PC5", "PC6", "SPC6" ]
[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Pregnancy" ]
[ "Hydrolase", "Protease", "Serine protease" ]
[]
[ "Golgi apparatus" ]
[]
[ "Secreted to blood" ]
[ "Enzyme" ]
Supported
Approved
null
17
null
null
Cluster 33: Non-specific - ATP binding
Cluster 51: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
2,060
4
ENSG00000099194
SCD
Stearoyl-CoA desaturase
[ "O00767" ]
10
100347233-100364826
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012107", "HPA063921" ]
[ "FADS5", "SCD1", "SCDOS" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Fatty acid biosynthesis", "Fatty acid metabolism", "Lipid biosynthesis", "Lipid metabolism" ]
[ "Oxidoreductase" ]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Enhanced
Approved
null
53
No
Yes
Cluster 30: Non-specific - DNA binding
Cluster 30: White matter - Myelination
Cluster 44: Connective tissue cells - ECM organization
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Bladder Urothelial Carcinoma" ]
[ "Bladder Urothelial Carcinoma" ]
2,061
9
ENSG00000099204
ABLIM1
Actin binding LIM protein 1
[ "O14639" ]
10
114431112-114768061
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038951", "HPA038952" ]
[ "ABLIM", "LIMAB1", "limatin" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[ "Cytosol" ]
[ "Connecting piece", "Mid piece" ]
[]
[]
Approved
Approved
null
35
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 35: Non-specific - DNA binding
Cluster 15: Kidney cancer - Membrane components
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 35: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,063
8
ENSG00000099246
RAB18
RAB18, member RAS oncogene family
[ "Q9NP72" ]
10
27504174-27543207
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA025928" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Protein transport", "Transport" ]
[ "Developmental protein", "Hydrolase" ]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
Uncertain
null
37
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 21: Non-specific - Metabolism
Cluster 52: Non-specific - Mitochondria
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
2,065
9
ENSG00000099256
PRTFDC1
Phosphoribosyl transferase domain containing 1
[ "Q9NRG1" ]
10
24848614-24952606
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021458" ]
[ "HHGP" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
Approved
Approved
null
17
null
null
null
Cluster 13: Oligodendrocytes - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
8
3
0
3
[ "Glioblastoma Multiforme" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
2,067
9
ENSG00000099260
PALMD
Palmdelphin
[ "Q9NP74" ]
1
99646113-99694541
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017959", "HPA030549" ]
[ "C1orf11", "FLJ20271", "PALML" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Actin filaments" ]
[ "Plasma membrane", "Focal adhesion sites" ]
[]
[]
Supported
Supported
null
3
null
null
null
Cluster 36: Choroid plexus - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,068
7
ENSG00000099282
TSPAN15
Tetraspanin 15
[ "O95858" ]
10
69451465-69507666
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044657", "HPA071160" ]
[ "NET-7", "TM4SF15" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Nuclear bodies", "Plasma membrane" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Approved
Approved
null
131
null
null
Cluster 1: T-cells - Unknown function
Cluster 30: White matter - Myelination
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
6
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,069
8
ENSG00000099284
MACROH2A2
MacroH2A.2 histone
[ "Q9P0M6" ]
10
70052544-70112282
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035865", "HPA041189" ]
[ "H2AFY2" ]
[ "Predicted intracellular proteins" ]
[]
[ "Chromatin regulator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
null
31
No
No
Cluster 26: Monocytes - Plasma membrane proteins
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 12: Bone cancer - Neuronal signaling
Cluster 89: Adipocytes - Lipid metabolism
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Bladder Urothelial Carcinoma", "Glioblastoma Multiforme" ]
[]
[ "Bladder Urothelial Carcinoma", "Glioblastoma Multiforme" ]
2,070
7
ENSG00000099290
WASHC2A
WASH complex subunit 2A
[ "Q641Q2" ]
10
50067888-50133509
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047844", "HPA060975", "HPA061022" ]
[ "bA56A21.1", "bA98I6.1", "FAM21A", "FAM21B", "FLJ10824" ]
[ "Predicted intracellular proteins", "Transporters" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Vesicles" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Supported
Supported
null
17
null
null
Cluster 33: Non-specific - ATP binding
Cluster 37: Neurons - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 35: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
2,071
2
ENSG00000099308
MAST3
Microtubule associated serine/threonine kinase 3
[ "O60307" ]
19
18097778-18151692
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035061", "HPA035062" ]
[ "KIAA0561" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Nuclear speckles" ]
[]
[]
[]
Approved
Uncertain
null
13
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 51: Neurons - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in many
null
2
0
2
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Head and Neck Squamous Cell Carcinoma" ]
2,072
4
ENSG00000099326
MZF1
Myeloid zinc finger 1
[ "P28698" ]
19
58561931-58573575
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001757" ]
[ "MZF-1", "MZF1B", "Zfp98", "ZNF42", "ZSCAN6" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
14
null
null
Cluster 24: Non-specific - Transcription
Cluster 50: Non-specific - Nucleic acid binding
Cluster 4: Non-specific - Transcription
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
2,073
5
ENSG00000099330
OCEL1
Occludin/ELL domain containing 1
[ "Q9H607" ]
19
17226213-17229219
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA042070", "HPA043223" ]
[ "FLJ22709" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 45: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
2,074
9
ENSG00000099331
MYO9B
Myosin IXB
[ "Q13459" ]
19
17075777-17214537
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037190", "HPA042043" ]
[ "CELIAC4" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding", "Calmodulin-binding", "GTPase activation", "Motor protein", "Myosin" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
23
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 11: White matter - Signal transduction
Cluster 23: Non-specific - Transcription
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 5: Spleen - Immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
2,075
3
ENSG00000099337
KCNK6
Potassium two pore domain channel subfamily K member 6
[ "Q9Y257" ]
19
38319845-38332076
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB022637", "HPA040184" ]
[ "K2p6.1", "TWIK-2" ]
[ "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Potassium channel", "Voltage-gated channel" ]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Actin filaments" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 6: Non-specific - Immune response
Cluster 64: Connective tissue cells - ECM organization
Cluster 82: Dendritic cells - Antigen presentation
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
2,076
5
ENSG00000099338
CATSPERG
Cation channel sperm associated auxiliary subunit gamma
[ "Q6ZRH7" ]
19
38335775-38370943
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA052777" ]
[ "C19orf15", "DKFZp434A1022", "FLJ46353" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "Transporters" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[ "Mid piece" ]
[ "Principal piece" ]
[ "Secreted in male reproductive system" ]
[ "Developmental protein" ]
Approved
null
null
null
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 6: Non-specific - Immune response
Cluster 15: Kidney cancer - Membrane components
Cluster 65: Non-specific - Cell growth & division
Cluster 67: Testis - Mixed function
Tissue enriched
Detected in some
13
Not detected
Not detected
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
2,077
4
ENSG00000099341
PSMD8
Proteasome 26S subunit, non-ATPase 8
[ "P48556" ]
19
38374563-38383850
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006702", "CAB021101" ]
[ "HIP6", "HYPF", "Nin1p", "p31", "Rpn12", "S14" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[ "Nuclear speckles" ]
[]
[]
Approved
Supported
null
76
null
null
Cluster 33: Non-specific - ATP binding
Cluster 14: Neurons - Synaptic function
Cluster 4: Non-specific - Transcription
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
2,078
6
ENSG00000099364
FBXL19
F-box and leucine rich repeat protein 19
[ "Q6PCT2" ]
16
30923055-30948783
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA074250" ]
[ "CXXC11", "DKFZp434K0410", "Fbl19", "JHDM1C" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
11
null
No
Cluster 2: Dendritic cells - Unknown function
Cluster 32: Cerebral cortex - Mixed function
Cluster 54: Non-specific - Transcription
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
2,079
7
ENSG00000099377
HSD3B7
Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
[ "Q9H2F3" ]
16
30985207-30989147
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015965", "HPA050521", "HPA060847" ]
[ "C(27)-3BETA-HSD", "SDR11E3" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism", "Steroidogenesis" ]
[ "Oxidoreductase" ]
[ "Disease variant", "Intrahepatic cholestasis" ]
[ "Lipid droplets" ]
[]
[]
[]
Enhanced
Approved
null
48
null
null
Cluster 22: Eosinophils - Transcription
Cluster 15: Non-specific - Transcription
Cluster 15: Kidney cancer - Membrane components
Cluster 108: Fibroblasts - ECM organization
Cluster 31: Liver - Metabolism & Coagulation
Tissue enriched
Detected in all
5
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
27
0
0
0
[]
[]
[]
2,081
1
ENSG00000099381
SETD1A
SET domain containing 1A, histone lysine methyltransferase
[ "O15047" ]
16
30957754-30984664
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020646", "HPA058376" ]
[ "KIAA0339", "KMT2F", "Set1", "SET1A" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "DNA damage", "Transcription", "Transcription regulation" ]
[ "Activator", "Chromatin regulator", "Methyltransferase", "RNA-binding", "Transferase" ]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Nuclear speckles" ]
[]
[]
[]
Supported
Enhanced
null
36
null
null
Cluster 22: Eosinophils - Transcription
Cluster 16: Non-specific - Transcription
Cluster 54: Non-specific - Transcription
Cluster 17: Non-specific - RNA processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,082
8
ENSG00000099385
BCL7C
BAF chromatin remodeling complex subunit BCL7C
[ "Q8WUZ0" ]
16
30833626-30894302
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA018676", "HPA052654" ]
[ "SMARCJ3" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
37
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 46: Brainstem - Mixed function
Cluster 54: Non-specific - Transcription
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,083
6
ENSG00000099399
MAGEB2
MAGE family member B2
[ "O15479" ]
X
30215563-30220089
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065224", "HPA074544", "HPA075519" ]
[ "CT3.2", "DAM6", "MAGE-XP-2", "MGC26438" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Tumor antigen" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
190
null
Yes
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in single
60
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
6
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Bladder Urothelial Carcinoma" ]
[ "Bladder Urothelial Carcinoma" ]
2,084
6
ENSG00000099617
EFNA2
Ephrin A2
[ "O43921" ]
19
1285873-1301431
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA067567" ]
[ "ELF-1", "EPLG6", "LERK6" ]
[ "Cancer-related genes", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[]
[]
[ "Cancer-related genes" ]
[ "Mitochondria", "Cytosol" ]
[]
[ "Intracellular and membrane" ]
[ "No annotated function" ]
Approved
null
null
33
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 70: DU4475 - Unknown function
Cluster 20: Non-specific - Transcription regulation
Cluster 77: Intestine - Digestion
Group enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Colon Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Lung Adenocarcinoma" ]
2,085
8
ENSG00000099624
ATP5F1D
ATP synthase F1 subunit delta
[ "P30049" ]
19
1241746-1244825
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002865" ]
[ "ATP5D" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "ATP synthesis", "Hydrogen ion transport", "Ion transport", "Transport" ]
[]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Mitochondria", "Principal piece" ]
[ "Connecting piece", "Flagellar centriole" ]
[]
[]
Supported
Approved
null
30
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 45: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 68: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
2,087
7
ENSG00000099625
CBARP
CACN subunit beta associated regulatory protein
[ "Q8N350" ]
19
1228287-1238027
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA012777" ]
[ "BARP", "C19orf26", "DOS", "MGC40084" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
12
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 78: Brain - Neuronal signaling
Group enriched
Detected in some
4
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,088
7
ENSG00000099769
IGFALS
Insulin like growth factor binding protein acid labile subunit
[ "P35858" ]
16
1790413-1794971
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040692", "HPA040948" ]
[ "ALS" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[]
[ "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Cell adhesion" ]
null
Supported
null
1
null
null
null
Cluster 6: Non-specific - Immune response
Cluster 15: Kidney cancer - Membrane components
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 31: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
10
Low cancer specificity
Detected in single
null
Cancer enhanced
Detected in many
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,091
2
ENSG00000099783
HNRNPM
Heterogeneous nuclear ribonucleoprotein M
[ "P52272" ]
19
8444767-8489114
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016113", "HPA024344" ]
[ "CEAR", "HNRNPM4", "HNRPM", "HNRPM4", "HTGR1", "NAGR1" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Ribonucleoprotein", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Supported
null
131
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 55: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 17: Non-specific - RNA processing
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
4
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,092
8
ENSG00000099785
MARCHF2
Membrane associated ring-CH-type finger 2
[ "Q9P0N8" ]
19
8413270-8439017
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014063" ]
[ "HSPC240", "MARCH-II", "MARCH2", "RNF172" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Endocytosis", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Endoplasmic reticulum" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
29
null
null
Cluster 41: Basophils - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 47: Platelets - Hemostasis
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
7
Low immune cell specificity
Detected in all
null
2
0
2
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Rectum Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Rectum Adenocarcinoma" ]
2,093
2
ENSG00000099795
NDUFB7
NADH:ubiquinone oxidoreductase subunit B7
[ "P17568" ]
19
14566078-14572066
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002817" ]
[ "B18", "CI-B18", "MGC2480" ]
[ "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[]
[ "Primary mitochondrial disease" ]
[]
[]
[]
[]
null
Enhanced
null
54
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 45: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
2,094
8
ENSG00000099800
TIMM13
Translocase of inner mitochondrial membrane 13
[ "Q9Y5L4" ]
19
2425625-2427586
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048985" ]
[ "Tim13", "TIMM13B" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Protein transport", "Translocation", "Transport" ]
[ "Chaperone" ]
[]
[ "Mitochondria" ]
[ "Nucleoli fibrillar center" ]
[]
[]
Supported
Uncertain
null
19
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 45: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,096
8
ENSG00000099804
CDC34
Cell division cycle 34, ubiqiutin conjugating enzyme
[ "P49427" ]
19
531760-542092
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002382", "CAB005109", "CAB047311", "HPA074334" ]
[ "E2-CDC34", "UBC3", "UBE2R1" ]
[ "Cancer-related genes", "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Ubl conjugation pathway" ]
[ "Transferase" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Nuclear speckles" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
35
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 32: Cerebral cortex - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
2,097
9
ENSG00000099812
MISP
Mitotic spindle positioning
[ "Q8IVT2" ]
19
751112-764318
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049511", "HPA062232" ]
[ "C19orf21", "Caprice", "DKFZp686H18209", "MISP1" ]
[ "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis" ]
[ "Actin-binding" ]
[]
[ "Plasma membrane", "Focal adhesion sites" ]
[]
[]
[]
Enhanced
Enhanced
null
77
No
No
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in many
9
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
2,099
6
ENSG00000099814
CEP170B
Centrosomal protein 170B
[ "Q9Y4F5" ]
14
104865268-104896747
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000871", "HPA001773", "HPA059017" ]
[ "Cep170R", "FAM68C", "KIAA0284" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Microtubule ends" ]
[ "Centrosome", "Cytosol" ]
[]
[]
Approved
Enhanced
null
19
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
2,100
2
ENSG00000099817
POLR2E
RNA polymerase II, I and III subunit E
[ "P19388" ]
19
1086574-1095380
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA063030", "HPA068992" ]
[ "hRPB25", "hsRPB5", "RPABC1", "RPB5", "XAP4" ]
[ "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins", "RNA polymerase related proteins" ]
[ "Host-virus interaction", "Transcription" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
318
null
null
Cluster 29: Non-specific - Unknown function
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 23: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 36: Brain & Liver - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
2,101
1
ENSG00000099821
POLRMT
RNA polymerase mitochondrial
[ "O00411" ]
19
617221-633537
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006366" ]
[ "APOLMT", "h-mtRPOL", "MTRNAP", "MTRPOL" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Transcription" ]
[ "Nucleotidyltransferase", "Transferase" ]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Uncertain
null
37
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 6: Non-specific - Immune response
Cluster 23: Non-specific - Transcription
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Rectum Adenocarcinoma" ]
2,102
3
ENSG00000099822
HCN2
Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
[ "Q9UL51" ]
19
589881-617159
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "BCNG-2", "BCNG2", "HAC-1" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ammonia transport", "Ion transport", "Potassium transport", "Sodium transport", "Transport" ]
[ "Ion channel", "Ligand-gated ion channel", "Potassium channel", "Sodium channel", "Voltage-gated channel" ]
[ "Disease variant", "Epilepsy" ]
[]
[]
[]
[]
null
null
null
2
null
null
null
Cluster 18: Non-specific - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in some
8
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
2,103
2
ENSG00000099834
CDHR5
Cadherin related family member 5
[ "Q9HBB8" ]
11
616577-626078
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA009081", "HPA009173", "CAB025004" ]
[ "FLJ20219", "MU-PCDH", "MUCDHL", "MUPCDH" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Differentiation" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
Cluster 6: Non-specific - Immune response
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Group enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
2,104
7
ENSG00000099840
IZUMO4
IZUMO family member 4
[ "Q1ZYL8" ]
19
2096429-2099593
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA048496" ]
[ "C19orf36" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins", "Transporters" ]
[]
[]
[]
[ "Equatorial segment", "Calyx", "Connecting piece" ]
[]
[ "Secreted in male reproductive system" ]
[ "No annotated function" ]
Approved
Enhanced
null
null
null
null
Cluster 33: Non-specific - ATP binding
Cluster 47: Endothelial cells - Vasculature
Cluster 46: Lymphoma - Humoral immune response
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in many
23
Group enriched
Detected in some
5
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
21
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
2,105
4
ENSG00000099849
RASSF7
Ras association domain family member 7
[ "Q02833" ]
11
560404-564025
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA078015" ]
[ "C11orf13", "CFAP88", "FAP88", "HRAS1", "HRC1" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Centriolar satellite" ]
[]
[]
[]
Supported
null
null
16
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 37: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
4
0
4
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
2,106
3
ENSG00000099860
GADD45B
Growth arrest and DNA damage inducible beta
[ "O75293" ]
19
2476122-2478259
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029816", "HPA063918" ]
[ "DKFZP566B133", "GADD45BETA", "MYD118" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis", "Differentiation" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Approved
Approved
null
10
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 103: Non-specific - Basic cellular processes
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Rectum Adenocarcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma", "Rectum Adenocarcinoma" ]
2,107
5
ENSG00000099864
PALM
Paralemmin
[ "O75781" ]
19
708935-748329
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041713", "HPA049578" ]
[ "KIAA0270", "PALM1" ]
[ "Predicted intracellular proteins" ]
[ "Cell shape" ]
[]
[]
[ "Nucleoplasm", "Plasma membrane" ]
[]
[]
[]
Enhanced
Approved
null
7
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
5
0
0
0
[]
[]
[]
2,108
4
ENSG00000099866
MADCAM1
Mucosal vascular addressin cell adhesion molecule 1
[ "Q13477" ]
19
489176-505343
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB075699", "HPA077998" ]
[ "MACAM1" ]
[ "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 37: Neurons - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 5: Spleen - Immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
9
0
0
0
[]
[]
[]
2,109
7
ENSG00000099875
MKNK2
MAPK interacting serine/threonine kinase 2
[ "Q9HBH9" ]
19
2037465-2051244
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021875", "CAB037253", "HPA070499" ]
[ "GPRK7", "MNK2" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Apoptosis", "Translation regulation" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nuclear bodies" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Supported
Supported
null
7
No
No
Cluster 20: Non-specific - DNA binding
Cluster 25: Non-specific - Transcription
Cluster 55: Lymphoma - Immune response
Cluster 20: Non-specific - Transcription regulation
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Stomach Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Prostate Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Prostate Adenocarcinoma", "Stomach Adenocarcinoma" ]
2,110
6
ENSG00000099889
ARVCF
ARVCF delta catenin family member
[ "O00192" ]
22
19969896-20016823
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016162", "HPA055264", "HPA063675" ]
[]
[ "Predicted intracellular proteins" ]
[ "Cell adhesion", "mRNA processing", "mRNA splicing" ]
[]
[]
[ "Plasma membrane", "Cell Junctions" ]
[]
[]
[]
Enhanced
Enhanced
null
4
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 54: Non-specific - Transcription
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
5
0
5
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
2,111
8
ENSG00000099899
TRMT2A
TRNA methyltransferase 2 homolog A
[ "Q8IZ69" ]
22
20111875-20117392
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001077" ]
[ "HTF9C" ]
[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "tRNA processing" ]
[ "Methyltransferase", "RNA-binding", "Transferase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
12
null
null
Cluster 33: Non-specific - ATP binding
Cluster 27: Non-specific - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
6
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
2,112
5
ENSG00000099901
RANBP1
RAN binding protein 1
[ "P43487" ]
22
20115938-20127355
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065868", "HPA065931" ]
[ "HTF9A" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Cytosol" ]
[]
[]
[]
Enhanced
Supported
null
59
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,113
6
ENSG00000099904
ZDHHC8
Zinc finger DHHC-type palmitoyltransferase 8
[ "Q9ULC8" ]
22
20129456-20148007
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003422" ]
[ "DHHC8", "KIAA1292", "ZNF378" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Host-virus interaction" ]
[ "Acyltransferase", "Transferase" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
2
null
null
Cluster 41: Basophils - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
2,114
8
ENSG00000099910
KLHL22
Kelch like family member 22
[ "Q53GT1" ]
22
20441519-20495844
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040766" ]
[ "FLJ14360", "KELCHL" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis", "Ubl conjugation pathway" ]
[]
[ "Disease variant" ]
[ "Vesicles", "Microtubules", "Cytokinetic bridge", "Mitotic spindle" ]
[]
[]
[]
Supported
null
null
70
Yes
No
Cluster 33: Non-specific - ATP binding
Cluster 15: Non-specific - Transcription
Cluster 66: Non-specific - Mitochondria
Cluster 7: Non-specific - Transcription
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
2,115
6
ENSG00000099917
MED15
Mediator complex subunit 15
[ "Q96RN5" ]
22
20495913-20587632
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003179" ]
[ "Arc105", "CAG7A", "PCQAP", "TIG-1", "TNRC7" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
67
null
null
Cluster 33: Non-specific - ATP binding
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 66: Non-specific - Mitochondria
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
2,116
3
ENSG00000099937
SERPIND1
Serpin family D member 1
[ "P05546" ]
22
20774113-20787720
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB008639", "HPA055767" ]
[ "D22S673", "HC-II", "HC2", "HCF2", "HLS2" ]
[ "Candidate cardiovascular disease genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Blood coagulation", "Chemotaxis", "Hemostasis" ]
[ "Heparin-binding", "Protease inhibitor", "Serine protease inhibitor" ]
[ "Disease variant", "FDA approved drug targets", "Thrombophilia" ]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Blood coagulation" ]
Approved
Supported
null
4
null
null
Cluster 30: Non-specific - DNA binding
Cluster 36: Choroid plexus - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
5
Group enriched
Detected in many
15
Cancer enriched
Detected in many
44
Cell type enriched
Detected in many
5
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
2,117
5
ENSG00000099940
SNAP29
Synaptosome associated protein 29
[ "O95721" ]
22
20859007-20891214
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031823", "CAB037092", "HPA056492" ]
[ "CEDNIK", "SNAP-29" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Autophagy", "Cilium biogenesis/degradation", "Protein transport", "Transport" ]
[]
[ "Ichthyosis", "Neuropathy", "Palmoplantar keratoderma" ]
[ "Cytosol" ]
[ "Centrosome" ]
[]
[]
Supported
Supported
null
167
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 55: Non-specific - Transcription
Cluster 66: Non-specific - Mitochondria
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
2,118
7
ENSG00000099942
CRKL
CRK like proto-oncogene, adaptor protein
[ "P46109" ]
22
20917407-20953747
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000532", "HPA001100" ]
[]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Enhanced
Uncertain
null
89
null
null
Cluster 33: Non-specific - ATP binding
Cluster 19: Astrocytes - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 47: Platelets - Hemostasis
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,119
9
ENSG00000099949
LZTR1
Leucine zipper like transcription regulator 1
[ "Q8N653" ]
22
20982269-20999032
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA067852", "HPA068772", "HPA071248" ]
[ "BTBD29", "LZTR-1" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[ "Cancer-related genes", "Disease variant" ]
[ "Nucleoplasm" ]
[ "Centrosome", "Cytosol" ]
[]
[]
Approved
Approved
null
15
No
No
Cluster 33: Non-specific - ATP binding
Cluster 45: Non-specific - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 102: Non-specific - Mixed function
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
2,120
9