ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000100299 | ARSA | Arylsulfatase A | [
"P15289"
] | 22 | 50622754-50628173 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005554",
"CAB025183"
] | [
"ASA"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [
"Disease variant",
"Ichthyosis",
"Leukodystrophy",
"Metachromatic leukodystrophy"
] | [
"Golgi apparatus"
] | [
"Cytosol",
"Mid piece"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Uncertain | Enhanced | null | 37 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 66: Non-specific - Mitochondria | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 2,230 | 7 |
ENSG00000100300 | TSPO | Translocator protein | [
"P30536"
] | 22 | 43151547-43163242 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011232",
"HPA046260",
"HPA072304"
] | [
"BZRP",
"DBI",
"IBP",
"MBR",
"mDRC",
"PBR",
"pk18",
"PKBS",
"TSPO1"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"Predicted membrane proteins"
] | [
"Lipid transport",
"Transport"
] | [
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Mitochondria"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 18 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 66: Non-specific - Mitochondria | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,231 | 9 |
ENSG00000100302 | RASD2 | RASD family member 2 | [
"Q96D21"
] | 22 | 35540831-35553999 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005839"
] | [
"MGC:4834",
"Rhes",
"TEM2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 5 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 17: Non-specific - RNA processing | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in many | 7 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,232 | 2 |
ENSG00000100304 | TTLL12 | Tubulin tyrosine ligase like 12 | [
"Q14166"
] | 22 | 43166622-43187134 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003054",
"CAB046029"
] | [
"KIAA0153"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity"
] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 28 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 24: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,233 | 1 |
ENSG00000100307 | CBX7 | Chromobox 7 | [
"O95931"
] | 22 | 39120167-39152680 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011574",
"HPA048677",
"HPA056480"
] | [] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 43 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 32: Cerebral cortex - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 2 | 4 | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,234 | 1 |
ENSG00000100311 | PDGFB | Platelet derived growth factor subunit B | [
"P01127"
] | 22 | 39223359-39244982 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011604",
"HPA011972",
"CAB018341"
] | [
"SIS",
"SSV"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins",
"RAS pathway related proteins"
] | [] | [
"Developmental protein",
"Growth factor",
"Mitogen"
] | [
"Cancer-related genes",
"Disease variant",
"Proto-oncogene"
] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Growth factor"
] | Approved | Supported | null | 17 | null | null | Cluster 1: T-cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 2,235 | 9 |
ENSG00000100312 | ACR | Acrosin | [
"P10323"
] | 22 | 50738196-50745339 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048687"
] | [] | [
"Enzymes",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Disease variant"
] | [] | [] | [
"Secreted in male reproductive system"
] | [
"Enzyme"
] | null | Enhanced | null | 1 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in some | 28 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 30 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,236 | 5 |
ENSG00000100314 | CABP7 | Calcium binding protein 7 | [
"Q86V35"
] | 22 | 29720003-29731833 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016439"
] | [
"MGC57793"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in some | 9 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,237 | 8 |
ENSG00000100316 | RPL3 | Ribosomal protein L3 | [
"P39023"
] | 22 | 39312882-39320389 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003365",
"HPA055361"
] | [
"L3"
] | [
"Essential proteins",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [
"FDA approved drug targets"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 348 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 2,238 | 7 |
ENSG00000100320 | RBFOX2 | RNA binding fox-1 homolog 2 | [
"O43251"
] | 22 | 35738736-36028824 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006240",
"HPA006455",
"HPA075862"
] | [
"FOX-2",
"HNRBP2",
"HRNBP2",
"RBM9"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 50 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 2,240 | 2 |
ENSG00000100321 | SYNGR1 | Synaptogyrin 1 | [
"O43759"
] | 22 | 39349925-39385575 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029673",
"CAB034277"
] | [] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 3 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 32: Cerebral cortex - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 2,241 | 6 |
ENSG00000100325 | ASCC2 | Activating signal cointegrator 1 complex subunit 2 | [
"Q9H1I8"
] | 22 | 29788609-29838304 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001439",
"HPA052879"
] | [
"ASC1p100",
"DKFZp586O0223",
"FLJ21588"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Focal adhesion sites",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 26 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 66: Non-specific - Mitochondria | Cluster 84: Apical squamous epithelium - Cornification | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 2,243 | 5 |
ENSG00000100330 | MTMR3 | Myotubularin related protein 3 | [
"Q13615"
] | 22 | 29883169-30030868 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA034515",
"HPA034516"
] | [
"FYVE-DSP1",
"KIAA0371",
"ZFYVE10"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Uncertain | Uncertain | null | 21 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,244 | 9 |
ENSG00000100336 | APOL4 | Apolipoprotein L4 | [
"Q9BPW4"
] | 22 | 36189124-36204840 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA049797",
"HPA055435"
] | [
"APOLIV"
] | [
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Apolipoprotein"
] | Supported | Uncertain | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 47: Leukemia - Hemostasis | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 13: Lung - Secretion | Low tissue specificity | Detected in many | null | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 2,246 | 6 |
ENSG00000100341 | PNPLA5 | Patatin like phospholipase domain containing 5 | [
"Q7Z6Z6"
] | 22 | 43879678-43892013 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050409",
"HPA054211"
] | [
"dJ388M5.4",
"GS2L"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Mid piece",
"Annulus"
] | [] | [] | [] | Approved | Uncertain | null | 19 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 61: BICR 18 - Protein kinases | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,247 | 5 |
ENSG00000100342 | APOL1 | Apolipoprotein L1 | [
"O14791"
] | 22 | 36253071-36267530 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018885",
"CAB056156"
] | [
"APOL"
] | [
"Candidate cardiovascular disease genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Cholesterol metabolism",
"Lipid metabolism",
"Lipid transport",
"Steroid metabolism",
"Sterol metabolism",
"Transport"
] | [] | [
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Apolipoprotein"
] | null | Supported | null | 1 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 42: Choroid plexus - Mitochondria | Cluster 15: Kidney cancer - Membrane components | Cluster 68: Foveolar cells - Mucosal defense | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,248 | 2 |
ENSG00000100344 | PNPLA3 | Patatin like phospholipase domain containing 3 | [
"Q9NST1"
] | 22 | 43923792-43964488 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA058058"
] | [
"adiponutrin",
"ADPN",
"C22orf20",
"dJ796I17.1",
"FLJ22012",
"iPLA2epsilon"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Acyltransferase",
"Hydrolase",
"Transferase"
] | [
"Disease variant",
"Obesity"
] | [
"Nucleoli"
] | [
"Mitochondria",
"Cytosol"
] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 2,249 | 3 |
ENSG00000100345 | MYH9 | Myosin heavy chain 9 | [
"P35579"
] | 22 | 36281280-36388010 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001644",
"CAB015386",
"HPA064783"
] | [
"DFNA17",
"EPSTS",
"FTNS",
"MHA",
"NMHC-II-A",
"NMMHCA"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion",
"Cell shape"
] | [
"Actin-binding",
"Calmodulin-binding",
"Host cell receptor for virus entry",
"Motor protein",
"Myosin",
"Receptor"
] | [
"Alport syndrome",
"Cancer-related genes",
"Cataract",
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Plasma membrane",
"Actin filaments"
] | [
"Nuclear bodies",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 156 | No | No | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 47: Endothelial cells - Vasculature | Cluster 15: Kidney cancer - Membrane components | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 2,250 | 9 |
ENSG00000100346 | CACNA1I | Calcium voltage-gated channel subunit alpha1 I | [
"Q9P0X4"
] | 22 | 39570753-39689735 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA066992"
] | [
"Cav3.3"
] | [
"FDA approved drug targets",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Voltage-gated channel"
] | [
"Disease variant",
"FDA approved drug targets",
"Intellectual disability"
] | [
"Plasma membrane"
] | [
"Cell Junctions",
"Acrosome"
] | [] | [] | Approved | null | null | 2 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,251 | 3 |
ENSG00000100347 | SAMM50 | SAMM50 sorting and assembly machinery component | [
"Q9Y512"
] | 22 | 43955442-44010531 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA034537"
] | [
"CGI-51",
"OMP85",
"SAM50",
"TOB55",
"TRG-3",
"YNL026W"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 52 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 45: Non-specific - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 97: Non-specific - Cellular respiration | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,252 | 9 |
ENSG00000100350 | FOXRED2 | FAD dependent oxidoreductase domain containing 2 | [
"Q8IWF2"
] | 22 | 36487190-36507221 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031611",
"HPA031612"
] | [
"ERFAD",
"FLJ23322"
] | [
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Approved | null | 51 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 66: Non-specific - Mitochondria | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 5 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma",
"Thyroid Carcinoma"
] | 2,254 | 6 |
ENSG00000100351 | GRAP2 | GRB2 related adaptor protein 2 | [
"O75791"
] | 22 | 39901084-39973721 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005788",
"CAB022073"
] | [
"GADS",
"GRBLG",
"GrbX",
"Grf40",
"Mona"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Enhanced | null | 74 | null | null | Cluster 11: T-cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 59: Leukemia - T-cell receptor | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 80: Thymus - Adaptive immune response | Tissue enriched | Detected in many | 18 | Cancer enriched | Detected in some | 6 | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Group enriched | Detected in many | 7 | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,255 | 3 |
ENSG00000100353 | EIF3D | Eukaryotic translation initiation factor 3 subunit D | [
"O15371"
] | 22 | 36510855-36529184 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045882",
"HPA063330",
"HPA066216"
] | [
"eIF3-p66",
"eIF3-zeta",
"EIF3S7"
] | [
"Disease related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Protein biosynthesis"
] | [
"Initiation factor",
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 110 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 4 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,256 | 5 |
ENSG00000100354 | TNRC6B | Trinucleotide repeat containing adaptor 6B | [
"Q9UPQ9"
] | 22 | 40044817-40335808 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003180"
] | [
"KIAA1093"
] | [
"Disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"RNA-mediated gene silencing",
"Translation regulation"
] | [
"RNA-binding"
] | [
"Autism spectrum disorder",
"Disease variant",
"Intellectual disability"
] | [] | [] | [] | [] | null | Approved | null | 55 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 2: Neurons - Nucleosome | Cluster 66: Non-specific - Mitochondria | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,257 | 9 |
ENSG00000100359 | SGSM3 | Small G protein signaling modulator 3 | [
"Q96HU1"
] | 22 | 40370591-40410289 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048980"
] | [
"DJ1042K10.2",
"RabGAP-5",
"RABGAP5",
"RUSC3",
"RUTBC3"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Cell cycle",
"Growth arrest"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Approved | null | 5 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 32: Cerebral cortex - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 2,258 | 7 |
ENSG00000100360 | IFT27 | Intraflagellar transport 27 | [
"Q9BW83"
] | 22 | 36758202-36776256 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048791"
] | [
"BBS19",
"FAP156",
"RABL4",
"RAYL"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Differentiation",
"Protein transport",
"Spermatogenesis",
"Transport"
] | [] | [
"Bardet-Biedl syndrome",
"Ciliopathy",
"Disease variant",
"Obesity"
] | [] | [] | [] | [] | null | Uncertain | null | 45 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 3: Choroid plexus - Cilium | Cluster 27: Breast cancer - Unknown function | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 2,259 | 4 |
ENSG00000100362 | PVALB | Parvalbumin | [
"P20472"
] | 22 | 36800684-36819479 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002515",
"HPA048536"
] | [
"D22S749"
] | [
"Predicted intracellular proteins"
] | [] | [
"Muscle protein"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cell Junctions"
] | [] | [] | Approved | Enhanced | null | null | No | null | Cluster 4: Neutrophils - Degranulation | Cluster 38: Sub-cortical - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 109: Neurons - Neuronal signaling | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 9 | Cancer enriched | Detected in many | 32 | Cell type enriched | Detected in some | 6 | Immune cell enriched | Detected in single | 5 | 1 | 0 | 1 | [] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | 2,260 | 6 |
ENSG00000100364 | KIAA0930 | KIAA0930 | [
"Q6ICG6"
] | 22 | 45192244-45240894 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038091"
] | [
"bK268H5.C22.1",
"C22orf9"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear membrane",
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 22 | No | No | Cluster 29: Non-specific - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,261 | 9 |
ENSG00000100365 | NCF4 | Neutrophil cytosolic factor 4 | [
"Q15080"
] | 22 | 36860988-36878017 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010146",
"HPA036156",
"HPA057975"
] | [
"p40phox",
"SH3PXD4"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Chronic granulomatous disease",
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 8 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 49: HMC-1 - Innate immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Group enriched | Detected in all | 5 | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,262 | 2 |
ENSG00000100368 | CSF2RB | Colony stimulating factor 2 receptor subunit beta | [
"P32927"
] | 22 | 36913628-36940439 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA078677"
] | [
"betaGMR",
"CD131",
"IL3RB",
"IL5RB"
] | [
"CD markers",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"FDA approved drug targets"
] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | null | null | 17 | null | null | Cluster 41: Basophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 49: HMC-1 - Innate immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 47 | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in some | 5 | Group enriched | Detected in many | 7 | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | 2,263 | 4 |
ENSG00000100372 | SLC25A17 | Solute carrier family 25 member 17 | [
"O43808"
] | 22 | 40769630-40819399 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052708",
"HPA060972"
] | [
"PMP34"
] | [
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Transport"
] | [] | [] | [
"Peroxisomes"
] | [] | [] | [] | Supported | Approved | null | 7 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 55: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,264 | 2 |
ENSG00000100373 | UPK3A | Uroplakin 3A | [
"O75631"
] | 22 | 45284949-45295874 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018407",
"HPA018415"
] | [
"UPK3"
] | [
"Disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Disease variant"
] | [
"Nuclear membrane"
] | [
"Nuclear bodies"
] | [] | [] | Uncertain | Enhanced | null | 2 | null | null | Cluster 2: Dendritic cells - Unknown function | null | Cluster 27: Breast cancer - Unknown function | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 25: Non-specific - Basic cellular processes | Group enriched | Detected in some | 7 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 7 | Cell type enriched | Detected in some | 5 | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,265 | 9 |
ENSG00000100376 | FAM118A | Family with sequence similarity 118 member A | [
"Q9NWS6"
] | 22 | 45308968-45341955 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003902"
] | [
"bK268H5.C22.4",
"C22orf8",
"FLJ20635"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Intermediate filaments"
] | [
"Cytosol"
] | [] | [] | Uncertain | Uncertain | null | 12 | null | null | Cluster 18: Non-specific - Translation | Cluster 48: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Uterine Corpus Endometrial Carcinoma"
] | 2,266 | 4 |
ENSG00000100379 | KCTD17 | Potassium channel tetramerization domain containing 17 | [
"Q8N5Z5"
] | 22 | 37051739-37063390 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018459"
] | [
"FLJ12242"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Dystonia"
] | [] | [] | [] | [] | null | Uncertain | null | 39 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 33: Neurons - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 3 | 2 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,267 | 2 |
ENSG00000100380 | ST13 | ST13 Hsp70 interacting protein | [
"P50502"
] | 22 | 40824535-40856639 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043233",
"HPA046412",
"HPA047114",
"HPA047116"
] | [
"FAM10A1",
"HIP",
"HSPABP1",
"P48",
"SNC6"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Cytosol"
] | [
"Primary cilium",
"Primary cilium tip",
"Basal body"
] | [] | [] | Approved | Enhanced | null | 25 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 55: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,268 | 3 |
ENSG00000100387 | RBX1 | Ring-box 1 | [
"P62877"
] | 22 | 40951347-40973309 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003038"
] | [
"BA554C12.1",
"RNF75",
"ROC1"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Host-virus interaction",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 160 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 28: Oligodendrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,270 | 8 |
ENSG00000100393 | EP300 | E1A binding protein p300 | [
"Q09472"
] | 22 | 41092592-41180077 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000146",
"HPA003128",
"HPA004112"
] | [
"KAT3B",
"p300"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Cell cycle",
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Acyltransferase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Supported | Supported | null | 438 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 16: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,271 | 5 |
ENSG00000100395 | L3MBTL2 | L3MBTL histone methyl-lysine binding protein 2 | [
"Q969R5"
] | 22 | 41205282-41231271 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000815"
] | [
"dJ756G23.3",
"DKFZP761I141",
"H-l(3)mbt-l"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 80 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 11: White matter - Signal transduction | Cluster 66: Non-specific - Mitochondria | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 20: Pituitary gland - Hormone signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,272 | 9 |
ENSG00000100399 | CHADL | Chondroadherin like | [
"Q6NUI6"
] | 22 | 41229510-41240931 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005696",
"HPA024654"
] | [
"SLRR4B"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | null | Uncertain | null | null | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 30: White matter - Myelination | Cluster 69: Skin cancer - ECM organization | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in many | 7 | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,273 | 7 |
ENSG00000100401 | RANGAP1 | Ran GTPase activating protein 1 | [
"P46060"
] | 22 | 41244779-41286187 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004293",
"HPA050110",
"HPA062034"
] | [
"Fug1",
"KIAA1835",
"SD"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"GTPase activation"
] | [] | [
"Nuclear membrane"
] | [
"Vesicles",
"Cytosol",
"Flagellar centriole"
] | [] | [] | Supported | Supported | null | 64 | Yes | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 24: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 9 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 2,274 | 9 |
ENSG00000100403 | ZC3H7B | Zinc finger CCCH-type containing 7B | [
"Q9UGR2"
] | 22 | 41301525-41360147 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001784",
"HPA076092"
] | [
"DKFZp434K0920",
"FLJ13787",
"KIAA1031",
"RoXaN"
] | [
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Uncertain | Uncertain | null | 2 | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,275 | 6 |
ENSG00000100410 | PHF5A | PHD finger protein 5A | [
"Q7RTV0"
] | 22 | 41459717-41468692 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028885"
] | [
"bK223H9.2",
"INI",
"MGC1346",
"Rds3",
"SAP14b",
"SF3b14b",
"SF3B7"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 61 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 66: Non-specific - Mitochondria | Cluster 17: Non-specific - RNA processing | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,276 | 3 |
ENSG00000100412 | ACO2 | Aconitase 2 | [
"Q99798"
] | 22 | 41447830-41529273 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001097"
] | [
"ACONM"
] | [
"Citric acid cycle related proteins",
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Tricarboxylic acid cycle"
] | [
"Lyase"
] | [
"Disease variant",
"Neurodegeneration"
] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | Approved | 10 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 66: Non-specific - Mitochondria | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,277 | 2 |
ENSG00000100413 | POLR3H | RNA polymerase III subunit H | [
"Q9Y535"
] | 22 | 41525799-41544606 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046787"
] | [
"C25",
"KIAA1665",
"RPC8"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"RNA polymerase related proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity",
"Transcription"
] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Centrosome"
] | [] | [] | Supported | Approved | null | 56 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 44: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 78: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 2,278 | 3 |
ENSG00000100416 | TRMU | TRNA mitochondrial 2-thiouridylase | [
"O75648"
] | 22 | 46330875-46357340 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000824",
"HPA035273",
"HPA043300"
] | [
"FLJ10140",
"MTO2",
"MTU1",
"TRMT"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"RNA-binding",
"Transferase",
"tRNA-binding"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | 2 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 45: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,279 | 5 |
ENSG00000100417 | PMM1 | Phosphomannomutase 1 | [
"Q92871"
] | 22 | 41576900-41589871 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030712",
"HPA074950"
] | [
"Sec53"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Isomerase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 5 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 66: Non-specific - Mitochondria | Cluster 84: Apical squamous epithelium - Cornification | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 5 | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 2,280 | 4 |
ENSG00000100418 | DESI1 | Desumoylating isopeptidase 1 | [
"Q6ICB0"
] | 22 | 41598028-41621043 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA053415"
] | [
"D15Wsu75e",
"DESI-1",
"FAM152B",
"POST",
"PPPDE2"
] | [
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protease"
] | [] | [
"Cytosol"
] | [
"Cytokinetic bridge"
] | [] | [] | Approved | Approved | null | 29 | Yes | No | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 19: Astrocytes - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,281 | 4 |
ENSG00000100422 | CERK | Ceramide kinase | [
"Q8TCT0"
] | 22 | 46684410-46738252 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064699"
] | [
"dA59H18.2",
"dA59H18.3",
"DKFZp434E0211",
"FLJ21430",
"FLJ23239",
"hCERK",
"KIAA1646",
"LK4"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | null | null | 22 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 45: Non-specific - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 2,282 | 8 |
ENSG00000100425 | BRD1 | Bromodomain containing 1 | [
"O95696"
] | 22 | 49773283-49827873 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000807",
"HPA001063"
] | [
"BRL",
"BRPF2"
] | [
"Predicted intracellular proteins"
] | [
"Erythrocyte maturation"
] | [
"Chromatin regulator"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Enhanced | null | 34 | null | null | Cluster 24: Non-specific - Transcription | Cluster 15: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 3 | 2 | 2 | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 2,283 | 6 |
ENSG00000100426 | ZBED4 | Zinc finger BED-type containing 4 | [
"O75132"
] | 22 | 49853844-49890080 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045341"
] | [
"KIAA0637"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 15: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 2,284 | 7 |
ENSG00000100427 | MLC1 | Modulator of VRAC current 1 | [
"Q15049"
] | 22 | 50059391-50085426 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003040"
] | [
"KIAA0027",
"LVM",
"MLC",
"VL"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 14 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 39: Astrocytes - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in many | 7 | Group enriched | Detected in some | 6 | Cancer enriched | Detected in some | 72 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 2,285 | 7 |
ENSG00000100429 | HDAC10 | Histone deacetylase 10 | [
"Q969S8"
] | 22 | 50245183-50251405 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019662",
"CAB045977"
] | [
"DKFZP761B039"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Autophagy",
"DNA damage",
"DNA recombination",
"DNA repair"
] | [
"Hydrolase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Supported | null | 10 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 54: Non-specific - Transcription | Cluster 20: Non-specific - Transcription regulation | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Ovary Serous Cystadenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Prostate Adenocarcinoma"
] | 2,286 | 3 |
ENSG00000100433 | KCNK10 | Potassium two pore domain channel subfamily K member 10 | [
"P57789"
] | 14 | 88180103-88326907 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA030462"
] | [
"K2p10.1",
"PPP1R97",
"TREK-2",
"TREK2"
] | [
"Predicted membrane proteins"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 37: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 62 | 0 | 0 | 0 | [] | [] | [] | 2,287 | 8 |
ENSG00000100439 | ABHD4 | Abhydrolase domain containing 4, N-acyl phospholipase B | [
"Q8TB40"
] | 14 | 22598290-22612963 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000600"
] | [
"FLJ12816"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 9 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 46: Brainstem - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 56: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 2,288 | 5 |
ENSG00000100441 | KHNYN | KH and NYN domain containing | [
"O15037"
] | 14 | 24429286-24441843 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003402"
] | [
"KIAA0323"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear membrane",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 8 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 2,289 | 2 |
ENSG00000100442 | FKBP3 | FKBP prolyl isomerase 3 | [
"Q00688"
] | 14 | 45115599-45135319 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000864",
"CAB012232",
"CAB012520"
] | [
"FKBP-25",
"FKBP25"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Isomerase",
"Rotamase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 15 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 34: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | 2,290 | 8 |
ENSG00000100445 | SDR39U1 | Short chain dehydrogenase/reductase family 39U member 1 | [
"Q9NRG7"
] | 14 | 24439766-24442905 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044294",
"HPA075356"
] | [
"C14orf124",
"HCDI"
] | [
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 19: Astrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,291 | 4 |
ENSG00000100448 | CTSG | Cathepsin G | [
"P08311"
] | 14 | 24573518-24576250 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000110",
"HPA047737"
] | [
"CG"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Chemotaxis"
] | [
"Antibiotic",
"Antimicrobial",
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Enhanced | null | 34 | null | null | Cluster 2: Dendritic cells - Unknown function | null | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in many | 155 | Cancer enriched | Detected in some | 430 | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 4 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 2,292 | 7 |
ENSG00000100450 | GZMH | Granzyme H | [
"P20718"
] | 14 | 24606480-24609699 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029200"
] | [
"CCP-X",
"CGL-2",
"CSP-C",
"CTLA1",
"CTSGL2"
] | [
"Enzymes",
"Predicted secreted proteins"
] | [
"Cytolysis"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Enhanced | null | 53 | null | null | Cluster 1: T-cells - Unknown function | Cluster 8: Immune cells - Immune response | Cluster 71: Lymphoma - Inflammatory response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in single | 5 | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 15 | Group enriched | Detected in all | 5 | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 2,293 | 8 |
ENSG00000100453 | GZMB | Granzyme B | [
"P10144"
] | 14 | 24630954-24634267 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000376",
"HPA003418"
] | [
"CCPI",
"CGL-1",
"CGL1",
"CSP-B",
"CSPB",
"CTLA1",
"CTSGL1",
"HLP",
"SECT"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Apoptosis",
"Cytolysis"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [
"Calyx"
] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Enhanced | null | 3 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 71: Lymphoma - Inflammatory response | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Group enriched | Detected in many | 4 | Cancer enriched | Detected in some | 59 | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 7 | Immune cell enriched | Detected in all | 5 | 2 | 0 | 2 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | 2,294 | 6 |
ENSG00000100461 | RBM23 | RNA binding motif protein 23 | [
"Q86U06"
] | 14 | 22893204-22919182 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004144"
] | [
"CAPERbeta",
"FLJ10482",
"RNPC4"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"RNA-binding"
] | [] | [
"Intermediate filaments"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 14 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 16: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 2,295 | 7 |
ENSG00000100462 | PRMT5 | Protein arginine methyltransferase 5 | [
"O14744"
] | 14 | 22920525-22929408 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005525",
"CAB012459",
"HPA064708"
] | [
"HRMT1L5",
"SKB1",
"SKB1Hs"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Methyltransferase",
"Repressor",
"Transferase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 162 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 23: Choroid plexus - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 84: Apical squamous epithelium - Cornification | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,296 | 5 |
ENSG00000100479 | POLE2 | DNA polymerase epsilon 2, accessory subunit | [
"P56282"
] | 14 | 49643555-49688422 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027555"
] | [
"DPE2"
] | [
"Essential proteins",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA replication"
] | [
"DNA-binding"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Vesicles"
] | [] | [] | Supported | Uncertain | null | 24 | No | No | Cluster 16: Non-specific - Cell proliferation | Cluster 9: Non-specific - Receptor signaling | Cluster 30: Non-specific - Gene expression regulation | Cluster 66: Erythroid cells - Erythroid differentiation and maturation | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 4 | 4 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,299 | 2 |
ENSG00000100483 | VCPKMT | Valosin containing protein lysine methyltransferase | [
"Q9H867"
] | 14 | 50108632-50116600 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001146",
"HPA076561"
] | [
"C14orf138",
"METTL21D",
"VCP-KMT"
] | [
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 7 | null | null | Cluster 24: Non-specific - Transcription | Cluster 31: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 2,300 | 4 |
ENSG00000100485 | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2 | [
"Q07890"
] | 14 | 50117130-50231578 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB004577",
"HPA047368",
"HPA052689"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Disease variant"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 18 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,301 | 1 |
ENSG00000100490 | CDKL1 | Cyclin dependent kinase like 1 | [
"Q00532"
] | 14 | 50326265-50416461 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059605",
"HPA065919"
] | [
"KKIALRE"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Vesicles"
] | [
"Flagellar centriole",
"Mid piece"
] | [] | [] | Enhanced | Uncertain | null | 6 | null | null | Cluster 32: Basophils - Transcription | Cluster 53: Neurons - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,302 | 2 |
ENSG00000100504 | PYGL | Glycogen phosphorylase L | [
"P06737"
] | 14 | 50857891-50944483 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000962",
"HPA004119"
] | [
"GSD6"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism",
"Glycogen metabolism"
] | [
"Allosteric enzyme",
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant",
"Glycogen storage disease"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 17 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 71: Lymphoma - Inflammatory response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 4 | 2 | 3 | [] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,304 | 7 |
ENSG00000100505 | TRIM9 | Tripartite motif containing 9 | [
"Q9C026"
] | 14 | 50975262-51096061 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"RNF91",
"SPRING"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | 28 | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 10: Ciliated cells - Ion channel activity | Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in many | 7 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 8 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,305 | 1 |
ENSG00000100519 | PSMC6 | Proteasome 26S subunit, ATPase 6 | [
"P62333"
] | 14 | 52707178-52728590 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042823"
] | [
"p42",
"RPT5"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 188 | No | No | Cluster 25: Non-specific - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 84: Apical squamous epithelium - Cornification | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,306 | 4 |
ENSG00000100522 | GNPNAT1 | Glucosamine-phosphate N-acetyltransferase 1 | [
"Q96EK6"
] | 14 | 52775193-52791668 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044647"
] | [
"FLJ10607",
"Gpnat1"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [
"Disease variant",
"Dwarfism"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 31: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,307 | 1 |
ENSG00000100523 | DDHD1 | DDHD domain containing 1 | [
"Q8NEL9"
] | 14 | 53036745-53153323 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049870"
] | [
"iPLA1alpha",
"KIAA1705",
"PA-PLA1",
"PAPLA1",
"SPG28"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Lipid metabolism",
"Phospholipid metabolism"
] | [
"Hydrolase"
] | [
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [] | [] | [] | [] | null | Enhanced | null | 5 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 7: Non-specific - Transcription | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 2,308 | 9 |
ENSG00000100526 | CDKN3 | Cyclin dependent kinase inhibitor 3 | [
"Q16667"
] | 14 | 54396849-54420218 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB005285",
"HPA039311",
"HPA058874"
] | [
"CDI1",
"KAP"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Enhanced | null | null | 12 | null | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 2: Neurons - Nucleosome | Cluster 30: Non-specific - Gene expression regulation | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 39: Testis - Nuclear processes | Tissue enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 16 | Immune cell enhanced | Detected in many | null | 7 | 4 | 5 | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,309 | 5 |
ENSG00000100528 | CNIH1 | Cornichon family AMPA receptor auxiliary protein 1 | [
"O95406"
] | 14 | 54423561-54441391 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA002544"
] | [
"CNIH",
"CNIL",
"TGAM77"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"ER-Golgi transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Approved | null | 21 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 3: Rhabdoid - Membrane components | Cluster 97: Non-specific - Cellular respiration | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 2,310 | 1 |
ENSG00000100532 | CGRRF1 | Cell growth regulator with ring finger domain 1 | [
"Q99675"
] | 14 | 54509812-54539292 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002930"
] | [
"CGR19",
"RNF197"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell cycle",
"Growth arrest"
] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Uncertain | null | 33 | null | null | Cluster 32: Basophils - Transcription | Cluster 55: Non-specific - Transcription | Cluster 3: Rhabdoid - Membrane components | Cluster 47: Platelets - Hemostasis | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,311 | 1 |
ENSG00000100554 | ATP6V1D | ATPase H+ transporting V1 subunit D | [
"Q9Y5K8"
] | 14 | 67294371-67360265 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031515",
"HPA057316"
] | [
"ATP6M",
"VATD",
"VMA8"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Hydrogen ion transport",
"Ion transport",
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 63 | null | No | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 14: Neurons - Synaptic function | Cluster 30: Non-specific - Gene expression regulation | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,312 | 1 |
ENSG00000100557 | CCDC198 | Coiled-coil domain containing 198 | [
"Q9NVL8"
] | 14 | 57469300-57493867 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029202"
] | [
"C14orf105",
"FLJ10650"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Uncertain | null | null | 16 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 6: Non-specific - Immune response | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,313 | 2 |
ENSG00000100558 | PLEK2 | Pleckstrin 2 | [
"Q9NYT0"
] | 14 | 67386984-67412167 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001208"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Uncertain | Enhanced | null | 3 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 15: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 26: Keratinocytes - Keratinization | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 6 | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 2,314 | 5 |
ENSG00000100564 | PIGH | Phosphatidylinositol glycan anchor biosynthesis class H | [
"Q14442"
] | 14 | 67581955-67600286 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031624"
] | [
"GPI-H"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Autism spectrum disorder",
"Disease variant",
"Epilepsy"
] | [] | [] | [] | [] | null | Approved | null | 97 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 26: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 80: Oligodendrocytes - Myelination | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,315 | 5 |
ENSG00000100565 | LRRC74A | Leucine rich repeat containing 74A | [
"Q0VAA2"
] | 14 | 76826372-76870304 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA035094"
] | [
"C14orf166B",
"LRRC74"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | null | null | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 17 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 2,316 | 8 |
ENSG00000100567 | PSMA3 | Proteasome 20S subunit alpha 3 | [
"P25788"
] | 14 | 58244843-58272012 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000905"
] | [
"HC8"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 177 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 30: Non-specific - Gene expression regulation | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,317 | 6 |
ENSG00000100568 | VTI1B | Vesicle transport through interaction with t-SNAREs 1B | [
"Q9UEU0"
] | 14 | 67647085-67674820 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044121",
"HPA048150",
"HPA060118"
] | [
"VTI2"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | [] | Enhanced | Approved | null | 54 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 14: Neurons - Synaptic function | Cluster 30: Non-specific - Gene expression regulation | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma"
] | 2,318 | 6 |
ENSG00000100575 | TIMM9 | Translocase of inner mitochondrial membrane 9 | [
"Q9Y5J7"
] | 14 | 58408495-58427531 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002932"
] | [
"TIM9A"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Translocation",
"Transport"
] | [
"Chaperone"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 24: Non-specific - Transcription | Cluster 55: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 15: Non-specific - Protein processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,319 | 6 |
ENSG00000100577 | GSTZ1 | Glutathione S-transferase zeta 1 | [
"O43708"
] | 14 | 77320996-77331597 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004701"
] | [
"GSTZ1-1",
"MAAI",
"MAI"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Phenylalanine catabolism",
"Tyrosine catabolism"
] | [
"Isomerase",
"Multifunctional enzyme",
"Transferase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 13: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Bladder Urothelial Carcinoma"
] | [
"Bladder Urothelial Carcinoma"
] | 2,320 | 8 |
ENSG00000100578 | KIAA0586 | KIAA0586 | [
"Q9BVV6"
] | 14 | 58427385-58551297 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000846"
] | [
"JBTS23",
"Talpid3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Ciliopathy",
"Disease variant",
"Joubert syndrome"
] | [] | [] | [] | [] | null | Uncertain | null | 3 | null | null | Cluster 24: Non-specific - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,321 | 1 |
ENSG00000100583 | SAMD15 | Sterile alpha motif domain containing 15 | [
"Q9P1V8"
] | 14 | 77376689-77392163 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA030673",
"HPA030677"
] | [
"C14orf174",
"FAM15A",
"FLJ35963"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nuclear membrane"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,323 | 7 |
ENSG00000100591 | AHSA1 | Activator of HSP90 ATPase activity 1 | [
"O95433"
] | 14 | 77457870-77469472 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000903",
"CAB006244"
] | [
"Aha1",
"C14orf3",
"hAha1",
"p38"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction",
"Stress response"
] | [
"Chaperone"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 67 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,324 | 1 |
ENSG00000100592 | DAAM1 | Dishevelled associated activator of morphogenesis 1 | [
"Q9Y4D1"
] | 14 | 59188646-59371405 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026605",
"HPA064789"
] | [
"KIAA0666"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Wnt signaling pathway"
] | [
"Actin-binding"
] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Uncertain | null | 13 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 11: Neuronal - Sensory perception | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 2,325 | 9 |
ENSG00000100593 | ISM2 | Isthmin 2 | [
"Q6H9L7"
] | 14 | 77474394-77498816 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039314",
"HPA039742"
] | [
"FLJ32147",
"TAIL1",
"THSD3"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Centrosome",
"Cytosol"
] | [
"Secreted in female reproductive system"
] | [
"No annotated function"
] | Approved | Supported | null | 1 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 34: Testis cancer - Unknown function | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in some | 57 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma"
] | 2,326 | 3 |
ENSG00000100596 | SPTLC2 | Serine palmitoyltransferase long chain base subunit 2 | [
"O15270"
] | 14 | 77505997-77616637 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA075143"
] | [
"hLCB2a",
"KIAA0526",
"LCB2",
"LCB2A"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Lipid metabolism",
"Sphingolipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Plasma membrane"
] | [
"Cell Junctions"
] | [] | [] | Approved | null | null | 20 | null | No | Cluster 10: Non-specific - Membrane trafficking | Cluster 30: White matter - Myelination | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,327 | 3 |
ENSG00000100599 | RIN3 | Ras and Rab interactor 3 | [
"Q8TB24"
] | 14 | 92513781-92688994 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA079218"
] | [
"FLJ22439"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [] | [] | [] | [] | null | Approved | null | 16 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 49: HMC-1 - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 4 | 0 | 0 | 0 | [] | [] | [] | 2,328 | 8 |
ENSG00000100600 | LGMN | Legumain | [
"Q99538"
] | 14 | 92703807-92748679 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001426"
] | [
"LGMN1",
"PRSC1"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Enhanced | null | 17 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 51: Myeloma - Immunoglobulins | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 11 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 2,329 | 2 |
ENSG00000100601 | ALKBH1 | AlkB homolog 1, histone H2A dioxygenase | [
"Q13686"
] | 14 | 77672404-77708023 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044087",
"HPA060061"
] | [
"ABH",
"alkB",
"ALKBH",
"hABH"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"RNA repair",
"Transcription",
"Transcription regulation",
"Translation regulation"
] | [
"Dioxygenase",
"Lyase",
"Multifunctional enzyme",
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [
"Endoplasmic reticulum"
] | [] | [] | Supported | Approved | null | null | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 31: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 2,330 | 4 |
ENSG00000100603 | SNW1 | SNW domain containing 1 | [
"Q13573"
] | 14 | 77717599-77761207 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002457",
"CAB009931",
"HPA017370"
] | [
"Bx42",
"FUN20",
"NCoA-62",
"Prp45",
"PRPF45",
"SKIIP",
"SKIP",
"SKIP1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Supported | null | 310 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 50: Non-specific - Nucleic acid binding | Cluster 30: Non-specific - Gene expression regulation | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 2,331 | 4 |
ENSG00000100604 | CHGA | Chromogranin A | [
"P10645"
] | 14 | 92923150-92935285 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000023",
"HPA017369",
"CAB040544",
"CAB055506",
"CAB058688"
] | [
"PHE5",
"PHES"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Antibiotic",
"Antimicrobial",
"Fungicide"
] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Defense"
] | Approved | Enhanced | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 69: Parathyroid gland - Mixed function | Tissue enriched | Detected in many | 5 | Cancer enriched | Detected in many | 6 | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,332 | 9 |
ENSG00000100605 | ITPK1 | Inositol-tetrakisphosphate 1-kinase | [
"Q13572"
] | 14 | 92936914-93116320 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055230"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Isomerase",
"Kinase",
"Transferase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 19: Astrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 102: Non-specific - Mixed function | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 2,333 | 6 |
ENSG00000100612 | DHRS7 | Dehydrogenase/reductase 7 | [
"Q9Y394"
] | 14 | 60144119-60169856 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031121",
"HPA078401"
] | [
"retDSR4",
"SDR34C1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Nucleoplasm",
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 11 | No | No | Cluster 35: Neutrophils - Protein binding | Cluster 49: Hindbrain - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 6 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 2,334 | 6 |
ENSG00000100614 | PPM1A | Protein phosphatase, Mg2+/Mn2+ dependent 1A | [
"P35813"
] | 14 | 60245752-60299087 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029209"
] | [
"MGC9201",
"PP2CA",
"PP2Calpha"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 29 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 2,335 | 8 |
ENSG00000100625 | SIX4 | SIX homeobox 4 | [
"Q9UIU6"
] | 14 | 60709539-60724351 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031793",
"HPA031794"
] | [
"AREC3"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 7 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 2,336 | 8 |
ENSG00000100626 | GALNT16 | Polypeptide N-acetylgalactosaminyltransferase 16 | [
"Q8N428"
] | 14 | 69259277-69357033 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059136",
"HPA075325"
] | [
"GalNAc-T16",
"GALNTL1",
"KIAA1130"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 108: Fibroblasts - ECM organization | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 2,337 | 3 |
ENSG00000100628 | ASB2 | Ankyrin repeat and SOCS box containing 2 | [
"Q96Q27"
] | 14 | 93934166-93976739 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001546"
] | [
"ASB-2"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | null | null | 7 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in many | 7 | 0 | 0 | 0 | [] | [] | [] | 2,338 | 8 |
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