interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR016898 | 16,898 | Polyphosphate phosphotransferase | Polyphosphate_phosphotransfera | Family | 16,210 | false | false | This family represents NDP-polyphosphate phosphotransferases ( ), which use inorganic polyphosphate (polyP) as a donor to convert NDP to NTP and are key enzymes for polyP metabolism in bacteria [ , , ]. In M. tuberculosis, it is important for its survival in macrophages [ ]. Members of this protein family were first de... | [
"GO:0008976"
] | [
"polyphosphate kinase activity"
] | [
"molecular_function"
] | 1 | [
"PIRSF"
] | [
"PIRSF028756"
] | [
"PPK2_prd"
] | [
16210
] | 1 | [
"EC",
"METACYC",
"METACYC"
] | [
"2.7.4.-",
"PWY-5107",
"PWY-7039"
] | [
"EC:2.7.4.-",
"METACYC:PWY-5107",
"METACYC:PWY-7039"
] | 3 | [
"3rhf",
"4yeg",
"5lc9",
"5lcd",
"5ld1",
"5ldb",
"5ll0",
"5llb",
"5llf",
"5maq",
"5o6k",
"5o6m",
"6an9",
"6ang",
"6anh",
"6aqe",
"6aqn",
"6au0",
"6b18",
"7bmm",
"7nmj",
"7plj",
"9gia",
"9gp9",
"9h8j",
"9h8k",
"9h8l",
"9igq",
"9igr"
] | 29 | [
"PUB00020170",
"PUB00051190",
"PUB00099561",
"PUB00099562"
] | [
"12482933",
"19001261",
"24930102",
"19843229"
] | [
"Polyphosphate kinase (PPK2), a potent, polyphosphate-driven generator of GTP.",
"Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria.",
"Degradation of polyphosphates by polyphosphate kinases from Ruegeria pomeroyi.",
"Polyphosphate kinase 2: a modulator of nucl... | [
2002,
2008,
2014,
2009
] | 4 | [] | [
"IPR022300"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes",
"uncultured Caudovirales phage"
] | [
69,
15933,
17,
190,
1
] | 5 | [] | [] | 0 | true | Family | Polyphosphate phosphotransferase | Polyphosphate phosphotransferase | Polyphosphate_phosphotransfera | 9 |
IPR016899 | 16,899 | mRNA cap guanine-N7 methyltransferase, eukaryotes | mRNA_G-N7_MeTrfase_euk | Family | 3,295 | false | false | This entry includes mRNA (guanine-N(7))-methyltransferase, which methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. It binds RNA containing 5'-terminal GpppC [ , , , , , ]. This family of enzymes is found in nucleus [ , , ]. | [
"GO:0004482",
"GO:0006370"
] | [
"mRNA 5'-cap (guanine-N7-)-methyltransferase activity",
"7-methylguanosine mRNA capping"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PIRSF"
] | [
"PIRSF028762"
] | [
"ABD1"
] | [
3295
] | 1 | [
"EC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.1.1.56",
"PWY-7375",
"R-CEL-72086",
"R-CEL-77075",
"R-DME-72086",
"R-DME-77075",
"R-DRE-72086",
"R-DRE-77075",
"R-HSA-167160",
"R-HSA-72086",
"R-HSA-77075",
"R-MMU-72086",
"R-MMU-77075",
"R-RNO-72086",
"R-RNO-77075",
"R-SCE-72086",
"R-SCE-77075",
"R-SPO-72086",
"R-SPO-77075",
... | [
"EC:2.1.1.56",
"METACYC:PWY-7375",
"REACTOME:R-CEL-72086",
"REACTOME:R-CEL-77075",
"REACTOME:R-DME-72086",
"REACTOME:R-DME-77075",
"REACTOME:R-DRE-72086",
"REACTOME:R-DRE-77075",
"REACTOME:R-HSA-167160",
"REACTOME:R-HSA-72086",
"REACTOME:R-HSA-77075",
"REACTOME:R-MMU-72086",
"REACTOME:R-MMU-... | 20 | [
"1ri1",
"1ri2",
"1ri3",
"1ri4",
"1ri5",
"1z3c",
"2hv9",
"3bgv",
"3epp",
"5e8j",
"5e9j",
"5e9w",
"8q69",
"8q8g",
"8q9w",
"9mg0",
"9mg1",
"9mg2",
"9mg3",
"9mg4",
"9mg5",
"9mg6"
] | 22 | [
"PUB00027904",
"PUB00058114",
"PUB00058115",
"PUB00058116",
"PUB00058117",
"PUB00058118",
"PUB00058119",
"PUB00058120",
"PUB00058121"
] | [
"7623811",
"10679253",
"10347220",
"9790902",
"9705270",
"22099306",
"11018011",
"11114884",
"15767670"
] | [
"Yeast mRNA cap methyltransferase is a 50-kilodalton protein encoded by an essential gene.",
"Cloning and characterization of mRNA capping enzyme and mRNA (Guanine-7-)-methyltransferase cDNAs from Xenopus laevis.",
"Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransf... | [
1995,
2000,
1999,
1998,
1998,
2011,
2000,
2000,
2005
] | 9 | [
"IPR039753"
] | [] | 1 | 0 | 1 | [
"Eukaryota",
"unclassified Klosneuvirinae",
"viral metagenome"
] | [
3292,
2,
1
] | 3 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
5,
1,
1,
1,
4,
1,
1,
1,
7,
1,
1,
2
] | 12 | true | Family | mRNA cap guanine-N7 methyltransferase, eukaryotes | mRNA cap guanine-N7 methyltransferase, eukaryotes | mRNA_G-N7_MeTrfase_euk | 2 |
IPR016900 | 16,900 | Alpha-2-glucosyltransferase Alg10 | Alg10 | Family | 4,436 | false | false | Alg10 (asparagine-linked glycosylation) ( ) is a dolichyl-phosphoglucose-dependent glucosyltransferase which adds the terminal alpha-1,2 glucose to the lipid-linked Glc2Man9GlcNAc2 oligosaccharide. The terminal alpha-1,2-linked glucose residue is important for substrate recognition by the oligosaccharyltransferase [ ].... | [
"GO:0106073",
"GO:0006488"
] | [
"dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity",
"dolichol-linked oligosaccharide biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF04922",
"PIRSF028810",
"PTHR12989"
] | [
"DIE2_ALG10",
"Alpha1_2_glucosyltferase_Alg10",
""
] | [
4427,
2789,
4361
] | 3 | [
"EC",
"REACTOME"
] | [
"2.4.1.256",
"R-HSA-446193"
] | [
"EC:2.4.1.256",
"REACTOME:R-HSA-446193"
] | 2 | [] | 0 | [
"PUB00008706",
"PUB00019414",
"PUB00043473",
"PUB00066987"
] | [
"9722534",
"9597543",
"17189275",
"7565092"
] | [
"KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels.",
"The ALG10 locus of Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum: the terminal glucose of the lipid-linked ol... | [
1998,
1998,
2007,
1995
] | 4 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Iainarchaeum sp.",
"Eukaryota",
"marine sediment metagenome"
] | [
72,
1,
4362,
1
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
3,
1,
1,
2,
5,
3,
1,
6,
3,
1,
1,
13
] | 12 | true | Family | Alpha-2-glucosyltransferase Alg10 | Alpha-2-glucosyltransferase Alg10 | Alg10 | 7 |
IPR016901 | 16,901 | Anaphase-promoting complex subunit APC10/Doc1 | APC10/Doc1 | Family | 4,828 | false | false | The anaphase-promoting complex (APC) or cyclosome is a multi-subunit E3 protein ubiquitin ligase that regulates important events in mitosis, such as the initiation of anaphase and exit from telophase. The APC, in conjunction with other enzymes, assembles multi-ubiquitin chains on a variety of regulatory proteins, there... | [
"GO:0031145",
"GO:0005680"
] | [
"anaphase-promoting complex-dependent catabolic process",
"anaphase-promoting complex"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PIRSF",
"PANTHER",
"CDD"
] | [
"PIRSF028841",
"PTHR12936",
"cd08366"
] | [
"APC10_sub",
"",
"APC10"
] | [
2322,
4772,
4389
] | 3 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-DDI-141430",
"R-DDI-174048",
"R-DDI-174084",
"R-DDI-174154",
"R-DDI-174178",
"R-DDI-174184",
"R-DDI-176407",
"R-DDI-176408",
"R-DDI-176409",
"R-DDI-176412",
"R-DDI-179409",
"R-DDI-2467813",
"R-DDI-2559582",
"R-DDI-69017",
"R-DDI-983168",
"R-DME-141430",
"R-DME-174048",
"R-DME-17... | [
"REACTOME:R-DDI-141430",
"REACTOME:R-DDI-174048",
"REACTOME:R-DDI-174084",
"REACTOME:R-DDI-174154",
"REACTOME:R-DDI-174178",
"REACTOME:R-DDI-174184",
"REACTOME:R-DDI-176407",
"REACTOME:R-DDI-176408",
"REACTOME:R-DDI-176409",
"REACTOME:R-DDI-176412",
"REACTOME:R-DDI-179409",
"REACTOME:R-DDI-246... | 66 | [
"1gqp",
"1jhj",
"4ui9",
"5a31",
"5g04",
"5g05",
"5khr",
"5khu",
"5l9t",
"5l9u",
"5lcw",
"6q6g",
"6q6h",
"6tlj",
"6tm5",
"6tnt",
"8a3t",
"8a5y",
"8a61",
"8pkp",
"8tar",
"8tau",
"9gaw",
"9n9r",
"9n9s"
] | 25 | [
"PUB00014924",
"PUB00059221"
] | [
"11884135",
"18485873"
] | [
"Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit.",
"Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex."
] | [
2002,
2008
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4828
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
5,
2,
2,
1,
8,
2,
1,
5,
3,
1,
1,
10
] | 12 | true | Family | Anaphase-promoting complex subunit APC10/Doc1 | Anaphase-promoting complex subunit APC10/Doc1 | APC10/Doc1 | 8 |
IPR016902 | 16,902 | Vacuolar protein sorting-associated protein 41 | Vps41 | Family | 2,711 | false | false | This entry represents the eukaryotic Vacuolar protein sorting-associated protein 41 (Vps41). Vsp41 is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex, which is essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport [ , ... | [
"GO:0034058",
"GO:0046907"
] | [
"endosomal vesicle fusion",
"intracellular transport"
] | [
"biological_process",
"biological_process"
] | 2 | [
"PIRSF"
] | [
"PIRSF028921"
] | [
"VPS41"
] | [
2711
] | 1 | [
"REACTOME"
] | [
"R-HSA-9754560"
] | [
"REACTOME:R-HSA-9754560"
] | 1 | [
"7zu0"
] | 1 | [
"PUB00044536",
"PUB00053237",
"PUB00053238",
"PUB00099766",
"PUB00099767",
"PUB00099768",
"PUB00099769"
] | [
"9111041",
"10944212",
"9184222",
"32808683",
"23173123",
"33851776",
"33764426"
] | [
"Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae.",
"A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion.",
"Novel Golgi to vacuole delivery pa... | [
1997,
2000,
1997,
2020,
2013,
2021,
2021
] | 7 | [
"IPR045111"
] | [] | 1 | 0 | 1 | [
"Eukaryota"
] | [
2711
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea ma... | [
5,
1,
2,
1,
5,
1,
3,
6,
1,
1,
7
] | 11 | true | Family | Vacuolar protein sorting-associated protein 41 | Vacuolar protein sorting-associated protein 41 | Vps41 | 9 |
IPR016903 | 16,903 | Nucleolar complex-associated protein 3 | Nucleolar_cplx-assoc_3 | Family | 4,995 | false | false | Budding yeast nucleolar complex-associated protein 3 (Noc3) is required for initiation of DNA replication and for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm [ , ]. This entry also includes Noc3 homologues from animals and plants. The mammalian Noc3 is a ... | [] | [] | [] | 0 | [
"PIRSF",
"PANTHER"
] | [
"PIRSF028977",
"PTHR14428"
] | [
"Nucleolar_complex_p3",
""
] | [
3073,
4994
] | 2 | [] | [] | [] | 0 | [
"6elz",
"6em5",
"7nac",
"7nad",
"7ohr",
"7r6k",
"7r72",
"7r7a",
"8esq",
"8esr",
"8fkv",
"8fkw",
"8fkx",
"8fky",
"8i9v",
"8i9w",
"8i9x",
"8i9y",
"8i9z",
"8ia0",
"8v87"
] | 21 | [
"PUB00014737",
"PUB00020526",
"PUB00077025"
] | [
"12110182",
"11371346",
"15564382"
] | [
"Noc3p, a bHLH protein, plays an integral role in the initiation of DNA replication in budding yeast.",
"Maturation and intranuclear transport of pre-ribosomes requires Noc proteins.",
"Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation."
] | [
2002,
2001,
2004
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4995
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
5,
1,
1,
1,
3,
1,
1,
4,
3,
1,
1,
9
] | 12 | true | Family | Nucleolar complex-associated protein 3 | Nucleolar complex-associated protein 3 | Nucleolar_cplx-assoc_3 | 7 |
IPR016905 | 16,905 | Glycyl radical enzyme YjjI-like | Glycyl_radical_YjjI-like | Family | 2,027 | false | false | Members of this family are homologues to enzymes known to undergo activation by a radical SAM protein to create an active site glycyl radical. This family appears to be activated by the YjjW radical SAM protein, usually encoded by an adjacent gene. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF",
"NCBIFAM"
] | [
"PF11230",
"PIRSF028991",
"TIGR04040"
] | [
"YjjI-like",
"Glycl_rad_HI0521_prd",
"glycyl_YjjI"
] | [
2027,
1755,
1886
] | 3 | [
"GP"
] | [
"GenProp0938"
] | [
"GP:GenProp0938"
] | 1 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
2000,
5,
22
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Glycyl radical enzyme YjjI-like | Glycyl radical enzyme YjjI-like | Glycyl_radical_YjjI-like | 8 |
IPR016907 | 16,907 | Uncharacterised conserved protein UCP029033, periplasmic protein | UCP029033 | Family | 2,734 | false | false | This group represents a predicted periplasmic protein. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029033"
] | [
"UCP029033"
] | [
2734
] | 1 | [] | [] | [] | 0 | [
"7c50",
"7c51"
] | 2 | [] | [] | [] | [] | 0 | [
"IPR007497"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Capitella teleta",
"metagenomes"
] | [
2683,
1,
50
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029033, periplasmic protein | Uncharacterised conserved protein UCP029033, periplasmic protein | UCP029033 | 5 |
IPR016908 | 16,908 | Uncharacterised conserved protein UCP029037 | UCP029037 | Family | 984 | false | false | This group represents uncharacterised conserved proteins. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF10071",
"PIRSF029037"
] | [
"DUF2310",
"UCP029037_Zn_ribbon"
] | [
984,
803
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
982,
2
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029037 | Uncharacterised conserved protein UCP029037 | UCP029037 | 9 |
IPR016909 | 16,909 | Ribosomal RNA large subunit methyltransferase F | rRNA_lsu_MeTfrase_F | Family | 4,695 | false | false | This entry represents proteins that methylate the adenine in position 1618 of 23S rRNA which belong to the METT10D/rlmF family [ ]. | [
"GO:0008988",
"GO:0006364",
"GO:0005737"
] | [
"rRNA (adenine-N6-)-methyltransferase activity",
"rRNA processing",
"cytoplasm"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"HAMAP",
"NCBIFAM",
"PIRSF"
] | [
"MF_01848",
"NF008725",
"PIRSF029038"
] | [
"23SrRNA_methyltr_F",
"PRK11727.1",
"Mtase_YbiN_prd"
] | [
4532,
4671,
4616
] | 3 | [
"EC"
] | [
"2.1.1.181"
] | [
"EC:2.1.1.181"
] | 1 | [] | 0 | [
"PUB00052324"
] | [
"18021804"
] | [
"The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel."
] | [
2008
] | 1 | [
"IPR010286"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
4644,
34,
17
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Ribosomal RNA large subunit methyltransferase F | Ribosomal RNA large subunit methyltransferase F | rRNA_lsu_MeTfrase_F | 5 |
IPR016910 | 16,910 | Uncharacterised conserved protein UCP029195, PTS-EIIA 2 | UCP029195_PTS_EIIA2 | Family | 277 | false | false | This group represents an uncharacterised protein with PTS_EIIA 2 domain. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029195"
] | [
"UCP029195_PTS_EIIA2"
] | [
277
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
277
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029195, PTS-EIIA 2 | Uncharacterised conserved protein UCP029195, PTS-EIIA 2 | UCP029195_PTS_EIIA2 | 2 |
IPR016912 | 16,912 | Bacteriophage P2, GpU | Phage_P2_GpU | Family | 2,779 | false | false | This entry is represented by Bacteriophage P2, GpU. The characteristics of the protein distribution suggest prophage matches in addition to the phage matches. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029208"
] | [
"Phage_tail_GPU"
] | [
2779
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR009734"
] | [] | 1 | 0 | 1 | [
"Opisthokonta",
"Pseudomonadati",
"Viruses",
"metagenomes"
] | [
4,
2645,
123,
7
] | 4 | [] | [] | 0 | true | Family | Bacteriophage P2, GpU | Bacteriophage P2, GpU | Phage_P2_GpU | 8 |
IPR016913 | 16,913 | Uncharacterised conserved protein UCP029215 | UCP029215 | Family | 2,621 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF09979",
"PIRSF029215"
] | [
"DUF2213",
"UCP029215"
] | [
2621,
1504
] | 2 | [] | [] | [] | 0 | [
"9b40"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Stenosarchaea group",
"Viruses",
"metagenomes"
] | [
1987,
15,
9,
565,
45
] | 5 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029215 | Uncharacterised conserved protein UCP029215 | UCP029215 | 9 |
IPR016914 | 16,914 | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL | TrmL | Family | 18,479 | false | false | This entry represents tRNA (cytidine/uridine-2'-O-)-methyltransferase that methylate the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA) [ ]. They catalyse the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. Some unc... | [
"GO:0008168",
"GO:0001510"
] | [
"methyltransferase activity",
"RNA methylation"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"HAMAP",
"PIRSF",
"PANTHER",
"CDD"
] | [
"MF_01885",
"PIRSF029256",
"PTHR42971",
"cd18094"
] | [
"tRNA_methyltr_TrmL",
"SpoU_TrmH_prd",
"",
"SpoU-like_TrmL"
] | [
18131,
17303,
18468,
17725
] | 4 | [
"EC"
] | [
"2.1.1.207"
] | [
"EC:2.1.1.207"
] | 1 | [
"1j85",
"1mxi",
"3e5y",
"3l8u",
"3n4j",
"3n4k",
"4jak",
"4jal",
"4kdz",
"4kgn",
"4pzk",
"5co4",
"6ahw",
"6qh8",
"6qkv",
"7d51",
"7e3q",
"7e3r",
"7e3s",
"7e3t",
"8w9u",
"8zfi",
"9j5p"
] | 23 | [
"PUB00060403"
] | [
"20855540"
] | [
"YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors."
] | [
2010
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Pyrodictium delaneyi",
"unclassified sequences"
] | [
17531,
700,
1,
247
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
7,
1,
3,
8
] | 4 | true | Family | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL | TrmL | 7 |
IPR016915 | 16,915 | Uncharacterised conserved protein UCP029342 | UCP029342 | Family | 1,163 | false | false | This family represents uncharacterised proteins with no known function from bacteria. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029342"
] | [
"UCP029342_ErfK/YbiS/YcfS/YnhG"
] | [
1163
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadati",
"freshwater sediment metagenome"
] | [
3,
1158,
2
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029342 | Uncharacterised conserved protein UCP029342 | UCP029342 | 1 |
IPR016916 | 16,916 | Uncharacterised conserved protein UCP029389, subtilisin-related | UCP029389_subtilisin-related | Family | 54 | false | false | This entry contains proteins related to subtilisin-type serine proteases that belong to MEROPS peptidase family S8 but are classed as non-peptidase homologues, and which have no known function. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029389"
] | [
"Subtilisin_rel_PA1242"
] | [
54
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR015500"
] | [] | 1 | 0 | 1 | [
"Pseudomonadaceae"
] | [
54
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029389, subtilisin-related | Uncharacterised conserved protein UCP029389, subtilisin-related | UCP029389_subtilisin-related | 2 |
IPR016917 | 16,917 | Uncharacterised conserved protein UCP029393 | UCP029393 | Family | 855 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029393"
] | [
"UCP029393"
] | [
855
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR022584"
] | [] | 1 | 0 | 1 | [
"Bacteria"
] | [
855
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029393 | Uncharacterised conserved protein UCP029393 | UCP029393 | 6 |
IPR016918 | 16,918 | Uncharacterised conserved protein UCP029394 | UCP029394 | Family | 1,962 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029394"
] | [
"UCP029394"
] | [
1962
] | 1 | [] | [] | [] | 0 | [
"1tp6"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halobacteriales",
"Rhizopus delemar"
] | [
1950,
11,
1
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029394 | Uncharacterised conserved protein UCP029394 | UCP029394 | 4 |
IPR016919 | 16,919 | Uncharacterised conserved protein UCP029416, tyrosine-protein phosphatase, Mlr4629 | UCP029416_PTP | Family | 1,939 | false | false | This group represents a predicted tyrosine-protein phosphatase, Mlr4629 type. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029416"
] | [
"UCP029416_PTP"
] | [
1939
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Methanofastidiosum methylothiophilum",
"Opisthokonta",
"ecological metagenomes"
] | [
1927,
1,
2,
9
] | 4 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029416, tyrosine-protein phosphatase, Mlr4629 | Uncharacterised conserved protein UCP029416, tyrosine-protein phosphatase, Mlr4629 | UCP029416_PTP | 1 |
IPR016920 | 16,920 | Uncharacterised conserved protein UCP029477 | UCP029477 | Family | 3,206 | false | false | This entry represents a family of bacterial uncharacterised proteins that includes PA2169 from Pseudomonas aeruginosa ( ). This protein shows a ferritin-like topology with a four-helix-bundle fold that lacks metal-ion-binding site typical of the ferritin family but has a potential metal-binding site [ ]. Its function i... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029477"
] | [
"UCP029477"
] | [
3206
] | 1 | [] | [] | [] | 0 | [
"4etr"
] | 1 | [
"PUB00065044"
] | [
"23295481"
] | [
"The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery."
] | [
2013
] | 1 | [
"IPR011971"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
3196,
4,
6
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029477 | Uncharacterised conserved protein UCP029477 | UCP029477 | 9 |
IPR016921 | 16,921 | Uncharacterised conserved protein UCP029502 | UCP029502 | Family | 714 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF27731",
"PIRSF029502"
] | [
"UCP029502",
"UCP029502"
] | [
714,
267
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadaceae",
"Pseudomonas phage YMC12/01/R24"
] | [
713,
1
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029502 | Uncharacterised conserved protein UCP029502 | UCP029502 | 4 |
IPR016923 | 16,923 | Uncharacterised conserved protein UCP029509, membrane | UCP029509 | Family | 1,413 | false | false | This group represents a predicted membrane protein. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029509"
] | [
"UCP029509"
] | [
1413
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"marine sediment metagenome"
] | [
1409,
4
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029509, membrane | Uncharacterised conserved protein UCP029509, membrane | UCP029509 | 4 |
IPR016924 | 16,924 | Uncharacterised conserved protein UCP029543 | UCP029543 | Family | 680 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029543"
] | [
"UCP029543"
] | [
680
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR046735"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"unclassified sequences"
] | [
669,
11
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029543 | Uncharacterised conserved protein UCP029543 | UCP029543 | 7 |
IPR016925 | 16,925 | Uncharacterised conserved protein UCP029570 | UCP029570 | Family | 578 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029570"
] | [
"UCP029570"
] | [
578
] | 1 | [] | [] | [] | 0 | [
"9cgy"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"ecological metagenomes"
] | [
568,
10
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029570 | Uncharacterised conserved protein UCP029570 | UCP029570 | 5 |
IPR016926 | 16,926 | Uncharacterised conserved protein UCP029594 | UCP029594 | Family | 878 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. However, these proteins are predicted integral membrane proteins (with several transmembrane segments), and are present in an operon with a predicted multidrug efflux pump. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029594"
] | [
"UCP029594"
] | [
878
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR022604"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"marine sediment metagenome"
] | [
874,
4
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029594 | Uncharacterised conserved protein UCP029594 | UCP029594 | 9 |
IPR016927 | 16,927 | Lectin, sugar-binding | Lectin_sugar-bd | Family | 16 | false | false | This group represents a lectin LecB. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029595"
] | [
"Lectin_LecB"
] | [
16
] | 1 | [] | [] | [] | 0 | [
"1gzt",
"1uqx",
"1w8f",
"1w8h",
"2boi",
"2bv4",
"2chh",
"2jdh",
"2jdk",
"2jdp",
"2jdu",
"2jdy",
"3zdv",
"6s5p",
"6s5r",
"6s5s",
"6y0u",
"6y0w",
"7nef",
"7new",
"7prg",
"7psy"
] | 22 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadota"
] | [
16
] | 1 | [] | [] | 0 | true | Family | Lectin, sugar-binding | Lectin, sugar-binding | Lectin_sugar-bd | 7 |
IPR016929 | 16,929 | Imm52 family, TsiT-like | TsiT-like | Family | 167 | false | false | This entry represents a family of proteins specific to beta and gamma proteobacteria, including the type VI secretion system (T6SS) immunity protein TsiT from Pseudomonas aeruginosa ( ), which belongs to the Imm52 family. This protein can suppress the virulence of TseT [ ]. TsiT adopts a β-sandwich fold with nine α-hel... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029636"
] | [
"UCP029636"
] | [
167
] | 1 | [] | [] | [] | 0 | [
"4rho",
"6jdp",
"7dym",
"9owg",
"9oz0"
] | 5 | [
"PUB00100868",
"PUB00100869",
"PUB00100870"
] | [
"34371041",
"29632369",
"30834616"
] | [
"Structure and SAXS studies unveiled a novel inhibition mechanism of the Pseudomonas aeruginosa T6SS TseT-TsiT complex.",
"A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone-co-chaperone complex.",
"Structural characterization of the Imm52 family protein TsiT in Pseudomonas... | [
2021,
2018,
2019
] | 3 | [] | [] | 0 | 0 | null | [
"Pseudomonadota"
] | [
167
] | 1 | [] | [] | 0 | true | Family | Imm52 family, TsiT-like | Imm52 family, TsiT-like | TsiT-like | 3 |
IPR016930 | 16,930 | Uncharacterised conserved protein UCP029644, LysM, PA4035 | UCP029644 | Family | 945 | false | false | This group represents an uncharacterised protein with LysM motif, PA4035 type. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029644"
] | [
"UCP029644"
] | [
945
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"hydrothermal vent metagenome"
] | [
941,
4
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029644, LysM, PA4035 | Uncharacterised conserved protein UCP029644, LysM, PA4035 | UCP029644 | 4 |
IPR016931 | 16,931 | Uncharacterised conserved protein UCP029658, TPR | UCP029658_TPR | Family | 845 | false | false | This group represents an uncharacterised protein with TPR repeats, PA4299 type. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029658"
] | [
"UCP029658_TPR"
] | [
845
] | 1 | [] | [] | [] | 0 | [
"8odn"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadota",
"plant metagenome"
] | [
838,
7
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029658, TPR | Uncharacterised conserved protein UCP029658, TPR | UCP029658_TPR | 6 |
IPR016932 | 16,932 | Uncharacterised conserved protein UCP029669 | UCP029669 | Family | 894 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029669"
] | [
"UCP029669"
] | [
894
] | 1 | [] | [] | [] | 0 | [
"2hwj"
] | 1 | [] | [] | [] | [] | 0 | [
"IPR014956"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"mine drainage metagenome"
] | [
888,
5,
1
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029669 | Uncharacterised conserved protein UCP029669 | UCP029669 | 5 |
IPR016933 | 16,933 | Pentapeptide repeat-containing uncharacterised conserved protein UCP029688 | UCP029688_pentapep | Family | 742 | false | false | This group represents an uncharacterised protein with pentapeptide repeat. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029688"
] | [
"UCP29688_pentapep"
] | [
742
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
732,
10
] | 2 | [] | [] | 0 | true | Family | Pentapeptide repeat-containing uncharacterised conserved protein UCP029688 | Pentapeptide repeat-containing uncharacterised conserved protein UCP029688 | UCP029688_pentapep | 8 |
IPR016934 | 16,934 | Uncharacterised conserved protein UCP029691 | UCP029691 | Family | 104 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029691"
] | [
"UCP029691"
] | [
104
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR060704"
] | [] | 1 | 0 | 1 | [
"Pseudomonadota"
] | [
104
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029691 | Uncharacterised conserved protein UCP029691 | UCP029691 | 5 |
IPR016935 | 16,935 | Opine metallophore dehydrogenase | Opine_metallophore_DH | Family | 369 | false | false | A member of this family has been identified in Staphylococcus aureus as a dehydrogenase involved in the synthesis of a new opine metallophore, named staphylopine. It is encoded as part of an operon that also includes an histidine racemase and an enzyme distantly related to nicotianamine synthase [ ]. Staphylopine is in... | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF10100",
"PIRSF029692"
] | [
"Staph_opine_DH",
"UCP029692"
] | [
369,
60
] | 2 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"
] | [
"1.5.1.-",
"PWY-1723",
"PWY-5301",
"PWY-5748",
"PWY-7667",
"PWY-7668",
"PWY-8450",
"PWY-8451"
] | [
"EC:1.5.1.-",
"METACYC:PWY-1723",
"METACYC:PWY-5301",
"METACYC:PWY-5748",
"METACYC:PWY-7667",
"METACYC:PWY-7668",
"METACYC:PWY-8450",
"METACYC:PWY-8451"
] | 8 | [
"6c4l",
"6c4m",
"6c4n",
"6c4r",
"6c4t",
"6gmz",
"6h31",
"6h3d",
"6h3f",
"6pbm",
"6pbn",
"6pbp",
"6pbt"
] | 13 | [
"PUB00081137",
"PUB00092873"
] | [
"27230378",
"29618515"
] | [
"Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus.",
"Staphylopine, pseudopaline, and yersinopine dehydrogenases: A structural and kinetic analysis of a new functional class of opine dehydrogenase."
] | [
2016,
2018
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Lasius niger"
] | [
368,
1
] | 2 | [] | [] | 0 | true | Family | Opine metallophore dehydrogenase | Opine metallophore dehydrogenase | Opine_metallophore_DH | 4 |
IPR016936 | 16,936 | Uncharacterised conserved protein UCP029693 | UCP029693 | Family | 2,627 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF10095",
"PIRSF029693"
] | [
"DUF2333",
"UCP029693"
] | [
2627,
1757
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
2587,
2,
38
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029693 | Uncharacterised conserved protein UCP029693 | UCP029693 | 1 |
IPR016937 | 16,937 | Uncharacterised conserved protein UCP029727 | UCP029727 | Family | 895 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF029727"
] | [
"UCP029727"
] | [
895
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"marine sediment metagenome"
] | [
894,
1
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP029727 | Uncharacterised conserved protein UCP029727 | UCP029727 | 9 |
IPR016938 | 16,938 | Uncharacterised protein family UPF0317 | UPF0317 | Family | 4,669 | false | false | This family contains putative, uncharacterised proteins from bacteria that are related to mitochondrial D-glutamate cyclase. | [] | [] | [] | 0 | [
"HAMAP",
"NCBIFAM",
"PIRSF"
] | [
"MF_01830",
"NF003969",
"PIRSF029755"
] | [
"Hydro_lyase",
"PRK05463.1",
"UCP029755"
] | [
4315,
4517,
4611
] | 3 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"... | [
"4.2.1.-",
"PWY-2229",
"PWY-2467",
"PWY-5061",
"PWY-5367",
"PWY-5408",
"PWY-5409",
"PWY-5410",
"PWY-5644",
"PWY-5780",
"PWY-5793",
"PWY-5979",
"PWY-6322",
"PWY-6602",
"PWY-6627",
"PWY-6672",
"PWY-6679",
"PWY-6721",
"PWY-6749",
"PWY-6944",
"PWY-6945",
"PWY-6946",
"PWY-6948... | [
"EC:4.2.1.-",
"METACYC:PWY-2229",
"METACYC:PWY-2467",
"METACYC:PWY-5061",
"METACYC:PWY-5367",
"METACYC:PWY-5408",
"METACYC:PWY-5409",
"METACYC:PWY-5410",
"METACYC:PWY-5644",
"METACYC:PWY-5780",
"METACYC:PWY-5793",
"METACYC:PWY-5979",
"METACYC:PWY-6322",
"METACYC:PWY-6602",
"METACYC:PWY-6... | 53 | [
"2pif",
"3db9"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
4392,
231,
46
] | 3 | [
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family UPF0317 | Uncharacterised protein family UPF0317 | UPF0317 | 6 |
IPR016939 | 16,939 | Small ribosomal subunit protein mS23, fungi | Ribosomal_mS23_fun | Family | 1,689 | false | false | This entry represents a family of fungal 37S mitochondrial ribosomal mS23 proteins, previously known as S25, which are a component of the mitochondrial small ribosomal subunit [ ]. | [
"GO:0003735",
"GO:0005763"
] | [
"structural constituent of ribosome",
"mitochondrial small ribosomal subunit"
] | [
"molecular_function",
"cellular_component"
] | 2 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF13741",
"PIRSF029764",
"PTHR37799"
] | [
"MRP-S25",
"RSM25",
""
] | [
1689,
854,
1654
] | 3 | [] | [] | [] | 0 | [
"5mrc",
"5mre",
"5mrf",
"6yw5",
"6ywe",
"6ywx",
"6ywy",
"8d8k",
"8d8l",
"8om2",
"8om3",
"8om4"
] | 12 | [
"PUB00019866"
] | [
"11278769"
] | [
"Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues."
] | [
2001
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1689
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1,
1
] | 3 | true | Family | Small ribosomal subunit protein mS23, fungi | Small ribosomal subunit protein mS23, fungi | Ribosomal_mS23_fun | 6 |
IPR016942 | 16,942 | Uncharacterised conserved protein UCP030042 | UCP030042 | Family | 1,204 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030042"
] | [
"UCP030042"
] | [
1204
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halobacteriales",
"Rhizophagus irregularis",
"ecological metagenomes"
] | [
1175,
3,
1,
25
] | 4 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP030042 | Uncharacterised conserved protein UCP030042 | UCP030042 | 6 |
IPR016943 | 16,943 | Uncharacterised conserved protein UCP030050, HTH transcriptional regulator, BH1869 | UCP030050_HTH | Family | 1,016 | false | false | This group represents a predicted HTH transcriptional regulator, BH1869 type. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030050"
] | [
"UCP030050_HTH"
] | [
1016
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
1014,
2
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP030050, HTH transcriptional regulator, BH1869 | Uncharacterised conserved protein UCP030050, HTH transcriptional regulator, BH1869 | UCP030050_HTH | 9 |
IPR016944 | 16,944 | Uncharacterised conserved protein UCP030066 | UCP030066 | Family | 1,744 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030066"
] | [
"UCP030066"
] | [
1744
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR032808"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Halocatena marina"
] | [
1743,
1
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP030066 | Uncharacterised conserved protein UCP030066 | UCP030066 | 6 |
IPR016945 | 16,945 | Uncharacterised conserved protein UCP030092 | UCP030092 | Family | 328 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030092"
] | [
"UCP030092"
] | [
328
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR024515"
] | [] | 1 | 0 | 1 | [
"Bacillales"
] | [
328
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP030092 | Uncharacterised conserved protein UCP030092 | UCP030092 | 3 |
IPR016946 | 16,946 | Uncharacterised conserved protein UCP030125 | UCP030125 | Family | 138 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030125"
] | [
"UCP030125"
] | [
138
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
138
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP030125 | Uncharacterised conserved protein UCP030125 | UCP030125 | 6 |
IPR016947 | 16,947 | Uncharacterised phage-associated protein UCP030140 | UCP030140 | Family | 1,845 | false | false | This entry includes the bacteriophage gamma, ORF gammalsu0035. The characteristics of the protein distribution suggest prophage matches. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030140"
] | [
"UCP030140"
] | [
1845
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR014871"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Mesorhabditis spiculigera",
"Viruses",
"bioreactor metagenome"
] | [
1778,
1,
64,
2
] | 4 | [] | [] | 0 | true | Family | Uncharacterised phage-associated protein UCP030140 | Uncharacterised phage-associated protein UCP030140 | UCP030140 | 7 |
IPR016948 | 16,948 | Uncharacterised conserved protein UCP030175 | UCP030175 | Family | 179 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members of this entry are mainly found in firmicutes. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030175"
] | [
"UCP030175"
] | [
179
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
179
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP030175 | Uncharacterised conserved protein UCP030175 | UCP030175 | 7 |
IPR016949 | 16,949 | Damage-control phosphatase At2g17340 | At2g17340 | Family | 656 | false | false | This entry includes damage-control phosphatase At2g17340 from Arabidopsis, which is a metal-dependent phosphatase with probable damage-control functions [ ]. It has phosphatase activity against several substrates, including sugar phosphates and p-nitrophenyl phosphate(pNPP), preferring sugar phosphate substrates, inclu... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030210"
] | [
"UCP030210"
] | [
656
] | 1 | [] | [] | [] | 0 | [
"1xfi",
"2q40"
] | 2 | [
"PUB00088733"
] | [
"27322068"
] | [
"A family of metal-dependent phosphatases implicated in metabolite damage-control."
] | [
2016
] | 1 | [
"IPR004567"
] | [] | 1 | 0 | 1 | [
"Eukaryota"
] | [
656
] | 1 | [
"Arabidopsis thaliana",
"Drosophila melanogaster",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
16,
2,
2,
4
] | 4 | true | Family | Damage-control phosphatase At2g17340 | Damage-control phosphatase At2g17340 | At2g17340 | 8 |
IPR016950 | 16,950 | Mannosyltransferase, MA4085, predicted | Manno-Trfase_MA4085_prd | Family | 271 | false | false | This protein family represents a group of predicted mannosyltransferases, MA4085 type. This group of proteins include Dolichyl-phosphate-mannose-protein mannosyltransferase from the extremely halophilic archaea Haloarcula hispanica (Dpm4, also known as Agl23, ( ). This protein is involved in both N- and O-glycosylation... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030218"
] | [
"Mannosyltr_MA4085_prd"
] | [
271
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00099992"
] | [
"32706435"
] | [
"Agl22 and Agl23 are involved in the synthesis and utilization of the lipid-linked intermediates in the glycosylation pathways of the halophilic archaeaon Haloarcula hispanica."
] | [
2020
] | 1 | [
"IPR019962"
] | [] | 1 | 0 | 1 | [
"Methanobacteriota"
] | [
271
] | 1 | [] | [] | 0 | true | Family | Mannosyltransferase, MA4085, predicted | Mannosyltransferase, MA4085, predicted | Manno-Trfase_MA4085_prd | 2 |
IPR016951 | 16,951 | Haem oxygenase (decyclizing), plant | Haem_Oase_decyc_pln | Family | 1,697 | false | false | This group represents a haem oxygenase (decyclizing), plant type. | [] | [] | [] | 0 | [
"PIRSF",
"PANTHER"
] | [
"PIRSF030219",
"PTHR35703"
] | [
"Heme_Oase_decyc_pln",
""
] | [
631,
1697
] | 2 | [
"EC",
"METACYC"
] | [
"1.14.14.18",
"PWY-5874"
] | [
"EC:1.14.14.18",
"METACYC:PWY-5874"
] | 2 | [
"7cka",
"7eqh"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1697
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
17,
5,
31
] | 3 | true | Family | Haem oxygenase (decyclizing), plant | Haem oxygenase (decyclizing), plant | Haem_Oase_decyc_pln | 9 |
IPR016952 | 16,952 | Small heat shock protein, predicted, plant | Small_heat_shock_prot_prd_pln | Family | 79 | false | false | This group represents a predicted small heat shock protein, plant type. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030283"
] | [
"Small_HSP_plant_prd"
] | [
79
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR044656"
] | [] | 1 | 0 | 1 | [
"Brassicaceae"
] | [
79
] | 1 | [
"Arabidopsis thaliana"
] | [
20
] | 1 | true | Family | Small heat shock protein, predicted, plant | Small heat shock protein, predicted, plant | Small_heat_shock_prot_prd_pln | 7 |
IPR016953 | 16,953 | Uncharacterised conserved protein UCP030365 | UCP030365 | Family | 110 | false | false | This entry represents a group of uncharacterised proteins from plants. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030365"
] | [
"UCP030365"
] | [
110
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR060706"
] | [] | 1 | 0 | 1 | [
"Mesangiospermae"
] | [
110
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
8,
2,
2
] | 3 | true | Family | Uncharacterised conserved protein UCP030365 | Uncharacterised conserved protein UCP030365 | UCP030365 | 5 |
IPR016954 | 16,954 | Uncharacterised protein family, Vng0742h | Uncharacterised_Vng0742h | Family | 519 | false | false | This family of proteins is functionally uncharacterised. Some family members have been annotated as being involved in signal transduction, on the basis they possess a DICT domain ( ). However, there is no experimental evidence to support this function, and the DICT domain's suggested role in sensory function in highly ... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030471"
] | [
"STR_Vng0742h_prd"
] | [
519
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
519
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family, Vng0742h | Uncharacterised protein family, Vng0742h | Uncharacterised_Vng0742h | 9 |
IPR016955 | 16,955 | Autotransporter, YhjY, predicted | Autotranspt_YhjY_prd | Family | 590 | false | false | This group represents a predicted autotransporter, YhjY type. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways, known as the type IV pathway, was first described for the IgA1 protease [ ]. The protein component that mediates secretion through the outer membrane i... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030748"
] | [
"Autotransporter_YhjY_prd"
] | [
590
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00008434",
"PUB00043415"
] | [
"3027577",
"11004173"
] | [
"Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease.",
"Identification of RpoS (sigma(S))-regulated genes in Salmonella enterica serovar typhimurium."
] | [
1987,
2000
] | 2 | [] | [] | 0 | 0 | null | [
"Enterobacteriaceae"
] | [
590
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Autotransporter, YhjY, predicted | Autotransporter, YhjY, predicted | Autotranspt_YhjY_prd | 4 |
IPR016956 | 16,956 | Inner membrane protein YdjM | YdjM | Family | 1,728 | false | false | This entry represents the inner membrane protein YdjM from bacteria [ ]. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030780"
] | [
"Md_memb_hyd_prd"
] | [
1728
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00042652"
] | [
"15919996"
] | [
"Global topology analysis of the Escherichia coli inner membrane proteome."
] | [
2005
] | 1 | [
"IPR007404"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Methanobacteriota",
"Neoptera",
"sediment metagenome"
] | [
1721,
4,
2,
1
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Inner membrane protein YdjM | Inner membrane protein YdjM | YdjM | 7 |
IPR016957 | 16,957 | Uncharacterised conserved protein UCP030791 | UCP030791 | Family | 240 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members of this entry are mainly found in enterobacterales. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF27752",
"PIRSF030791"
] | [
"UCP030791",
"UCP030791"
] | [
240,
123
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Enterobacterales",
"human gut metagenome"
] | [
239,
1
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP030791 | Uncharacterised conserved protein UCP030791 | UCP030791 | 9 |
IPR016958 | 16,958 | Uncharacterised conserved protein UCP030798 | UCP030798 | Family | 831 | false | false | This entry represents a family of uncharacterised conserved proteins mainly found in Gammaproteobacteria, including Uncharacterized protein YjcB from Escherichia coli ( ). | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF15940",
"PIRSF030798"
] | [
"YjcB",
"UCP030798"
] | [
831,
770
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Lasius niger"
] | [
830,
1
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised conserved protein UCP030798 | Uncharacterised conserved protein UCP030798 | UCP030798 | 8 |
IPR016959 | 16,959 | Uncharacterised conserved protein UCP030811 | UCP030811 | Family | 573 | false | false | This group represents a uncharacterised conserved proteins from enterobacteriaceae. | [] | [] | [] | 0 | [
"NCBIFAM",
"PIRSF"
] | [
"NF011788",
"PIRSF030811"
] | [
"PRK15252.1",
"UCP030811"
] | [
349,
543
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Enterobacteriaceae"
] | [
573
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised conserved protein UCP030811 | Uncharacterised conserved protein UCP030811 | UCP030811 | 7 |
IPR016960 | 16,960 | Protein kinase YegI-like | YegI-like | Family | 216 | false | false | Proteins in this entry contain the protein kinase and the HhH DNA-binding domains. This entry includes YegI, a putative serine/threonine kinase [ ]. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030823"
] | [
"UCP030823_PK_HhH"
] | [
216
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00091092"
] | [
"29967116"
] | [
"Identification and biochemical characterization of a novel PP2C-like Ser/Thr phosphatase in E. coli."
] | [
2018
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
216
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein kinase YegI-like | Protein kinase YegI-like | YegI-like | 4 |
IPR016961 | 16,961 | Diacylglycerol kinase, plant | Diacylglycerol_kinase_pln | Family | 1,244 | false | false | This entry represents a group of plant diacylglycerol kinases, including Arabidopsis AtDGK3/4/5/7. They regulate the level of the second messenger diacylglycerol and produces phosphatidic acid (PA), another signalling molecule [ ]. | [
"GO:0004143"
] | [
"ATP-dependent diacylglycerol kinase activity"
] | [
"molecular_function"
] | 1 | [
"PIRSF"
] | [
"PIRSF030829"
] | [
"Diacylglycerol_kinase_pln"
] | [
1244
] | 1 | [
"EC",
"METACYC",
"METACYC"
] | [
"2.7.1.107",
"PWY-7039",
"PWY-7817"
] | [
"EC:2.7.1.107",
"METACYC:PWY-7039",
"METACYC:PWY-7817"
] | 3 | [] | 0 | [
"PUB00078074"
] | [
"16081412"
] | [
"Arabidopsis AtDGK7, the smallest member of plant diacylglycerol kinases (DGKs), displays unique biochemical features and saturates at low substrate concentration: the DGK inhibitor R59022 differentially affects AtDGK2 and AtDGK7 activity in vitro and alters plant growth and development."
] | [
2005
] | 1 | [
"IPR037607"
] | [] | 1 | 0 | 1 | [
"Magnoliopsida"
] | [
1244
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
17,
11,
6
] | 3 | true | Family | Diacylglycerol kinase, plant | Diacylglycerol kinase, plant | Diacylglycerol_kinase_pln | 3 |
IPR016962 | 16,962 | Dehydrase, ECs4332, predicted | Dehydrase_ECs4332_prd | Family | 978 | false | false | This group represents a predicted dehydrase, ECs4332 type. Some proteins in this entry share protein sequence similarity with 3-hydroxymyristoyl-(acyl carrier protein) dehydratase FabZ from E. coli [ ]. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF030962"
] | [
"Dehydrase_ECs4332_prd"
] | [
978
] | 1 | [] | [] | [] | 0 | [
"3esi",
"6qsr"
] | 2 | [
"PUB00013482"
] | [
"8910376"
] | [
"Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis."
] | [
1996
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halorubrum tibetense",
"ecological metagenomes"
] | [
968,
1,
9
] | 3 | [] | [] | 0 | true | Family | Dehydrase, ECs4332, predicted | Dehydrase, ECs4332, predicted | Dehydrase_ECs4332_prd | 6 |
IPR016963 | 16,963 | Glycoporin RafY | Glycoporin_RafY | Family | 1,328 | false | false | This group represents a glycoporin RafY. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF16966",
"PIRSF030989"
] | [
"Porin_8",
"Glycoporin_RafY"
] | [
1328,
518
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta"
] | [
1326,
2
] | 2 | [] | [] | 0 | true | Family | Glycoporin RafY | Glycoporin RafY | Glycoporin_RafY | 1 |
IPR016964 | 16,964 | Sigma intracellular receptor 2 | Sigma2_recept | Family | 2,793 | false | false | Sigma-2 receptor, also known as TMEM97, is an intracellular orphan receptor highly expressed in various rapidly proliferating cancer cells and regarded as a cancer cell biomarker. It is a cytochrome-related protein that binds to various pharmacological compounds, and modulates the cytosolic Ca2+ concentration, dopamine... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031032"
] | [
"TMP_97_prd"
] | [
2793
] | 1 | [] | [] | [] | 0 | [
"7m93",
"7m94",
"7m95",
"7m96",
"7mfi"
] | 5 | [
"PUB00077739",
"PUB00078073",
"PUB00086651",
"PUB00086652",
"PUB00086653"
] | [
"25566323",
"19583955",
"23922215",
"22292588",
"25620095"
] | [
"TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease.",
"Identification of cholesterol-regulating genes by targeted RNAi screening.",
"Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.",
"S2R(Pgrmc1): the cytochrome-related sigma-2 receptor th... | [
2014,
2009,
2014,
2012,
2015
] | 5 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2793
] | 1 | [
"Arabidopsis thaliana",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (st... | [
8,
1,
2,
1,
1,
6,
2,
1,
1,
2
] | 10 | true | Family | Sigma intracellular receptor 2 | Sigma intracellular receptor 2 | Sigma2_recept | 2 |
IPR016965 | 16,965 | Phosphatase PHOSPHO-type | Pase_PHOSPHO-typ | Family | 6,041 | false | false | This group represents phosphatases related to PHOSPHO1 and PHOSPHO2 [ ]. It includes plant phosphatases with homology to the haloacid dehalogenase (HAD) superfamily [ , ]. PHOSPHO1 is a phosphoethanolamine/phosphocholine phosphatase [ ], while PHOSPHO2 has high activity toward pyridoxal 5'-phosphate (PLP), and it is ac... | [
"GO:0016791"
] | [
"phosphatase activity"
] | [
"molecular_function"
] | 1 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF06888",
"PIRSF031051",
"PTHR20889"
] | [
"Put_Phosphatase",
"PyrdxlP_Pase_PHOSPHO2",
""
] | [
6039,
4609,
5553
] | 3 | [
"EC",
"GP",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"3.1.3",
"GenProp1702",
"R-DRE-1483191",
"R-DRE-1483213",
"R-HSA-1483191",
"R-HSA-1483213",
"R-MMU-1483191",
"R-MMU-1483213"
] | [
"EC:3.1.3",
"GP:GenProp1702",
"REACTOME:R-DRE-1483191",
"REACTOME:R-DRE-1483213",
"REACTOME:R-HSA-1483191",
"REACTOME:R-HSA-1483213",
"REACTOME:R-MMU-1483191",
"REACTOME:R-MMU-1483213"
] | 8 | [] | 0 | [
"PUB00012903",
"PUB00055587",
"PUB00055588",
"PUB00055589",
"PUB00055590"
] | [
"11161030",
"14983068",
"15175005",
"16054448",
"21122813"
] | [
"LEPS2, a phosphorus starvation-induced novel acid phosphatase from tomato.",
"Comparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily.",
"Human PHOSPHO1 exhibits high specific phosphoethanolamine and phosphocholine phosphatase activities.",
"Pr... | [
2001,
2003,
2004,
2005,
2011
] | 5 | [
"IPR006384"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Candidatus Heimdallarchaeum",
"Eukaryota",
"Siphoviridae sp. ctBLh2",
"ecological metagenomes"
] | [
327,
2,
5702,
1,
9
] | 5 | [
"Arabidopsis thaliana",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
15,
3,
4,
9,
7,
10,
6,
27
] | 8 | true | Family | Phosphatase PHOSPHO-type | Phosphatase PHOSPHO-type | Pase_PHOSPHO-typ | 2 |
IPR016966 | 16,966 | Thiamin pyrophosphokinase, eukaryotic | Thiamin_pyrophosphokinase_euk | Family | 3,147 | false | false | This group represents eukaryotic thiamin pyrophosphokinase. | [
"GO:0004788",
"GO:0005524",
"GO:0009229"
] | [
"thiamine diphosphokinase activity",
"ATP binding",
"thiamine diphosphate biosynthetic process"
] | [
"molecular_function",
"molecular_function",
"biological_process"
] | 3 | [
"PIRSF"
] | [
"PIRSF031057"
] | [
"Thiamin_pyrophosphokinase"
] | [
3147
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.7.6.2",
"PWY-6898",
"PWY-6907",
"PWY-6908",
"PWY-7356",
"R-BTA-196819",
"R-CEL-196819",
"R-HSA-196819",
"R-MMU-196819",
"R-SCE-196819"
] | [
"EC:2.7.6.2",
"METACYC:PWY-6898",
"METACYC:PWY-6907",
"METACYC:PWY-6908",
"METACYC:PWY-7356",
"REACTOME:R-BTA-196819",
"REACTOME:R-CEL-196819",
"REACTOME:R-HSA-196819",
"REACTOME:R-MMU-196819",
"REACTOME:R-SCE-196819"
] | 10 | [
"1ig0",
"1ig3",
"2f17",
"2g9z",
"2hh9",
"3s4y",
"9hjc"
] | 7 | [] | [] | [] | [] | 0 | [
"IPR006282"
] | [] | 1 | 0 | 1 | [
"Eukaryota"
] | [
3147
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Zea mays"
] | [
9,
1,
2,
3,
1,
4,
7,
1,
14
] | 9 | true | Family | Thiamin pyrophosphokinase, eukaryotic | Thiamin pyrophosphokinase, eukaryotic | Thiamin_pyrophosphokinase_euk | 5 |
IPR016968 | 16,968 | Uncharacterised conserved protein UCP031074 | UCP031074 | Family | 11 | false | false | This group consists of uncharacterised conserved proteins from the bacterial family Chlamydiaceae. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031074"
] | [
"UCP031074"
] | [
11
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Chlamydia"
] | [
11
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP031074 | Uncharacterised conserved protein UCP031074 | UCP031074 | 6 |
IPR016969 | 16,969 | Uncharacterised conserved protein UCP031088, alpha/beta hydrolase, At1g15070 | UCP031088_abhydr | Family | 1,043 | false | false | This group represents a predicted alpha/beta hydrolase, At1g15070 type, from plants. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031088"
] | [
"UCP031088_abhydr"
] | [
1043
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
1043
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
13,
7,
9
] | 3 | true | Family | Uncharacterised conserved protein UCP031088, alpha/beta hydrolase, At1g15070 | Uncharacterised conserved protein UCP031088, alpha/beta hydrolase, At1g15070 | UCP031088_abhydr | 4 |
IPR016970 | 16,970 | Uncharacterised conserved protein UCP031143 | UCP031143 | Family | 43 | false | false | This group represents a uncharacterised conserved proteins from enterobacteriaceae. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031143"
] | [
"UCP031143"
] | [
43
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR009568"
] | [] | 1 | 0 | 1 | [
"Brassicaceae"
] | [
43
] | 1 | [
"Arabidopsis thaliana"
] | [
12
] | 1 | true | Family | Uncharacterised conserved protein UCP031143 | Uncharacterised conserved protein UCP031143 | UCP031143 | 9 |
IPR016971 | 16,971 | Uncharacterised conserved protein UCP031277 | UCP031277 | Family | 1,343 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members of this entry are mainly found in plants. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF27754",
"PIRSF031277",
"PTHR34116"
] | [
"UCP031277",
"UCP031277",
""
] | [
1330,
663,
1323
] | 3 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1343
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
9,
13
] | 3 | true | Family | Uncharacterised conserved protein UCP031277 | Uncharacterised conserved protein UCP031277 | UCP031277 | 4 |
IPR016972 | 16,972 | Uncharacterised conserved protein UCP031279 | UCP031279 | Family | 2,188 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. Members of this group are mainly found in plants. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF",
"PANTHER"
] | [
"PF27755",
"PIRSF031279",
"PTHR33526"
] | [
"UCP031279",
"UCP031279",
""
] | [
2187,
1454,
2022
] | 3 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
2188
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
22,
14,
13
] | 3 | true | Family | Uncharacterised conserved protein UCP031279 | Uncharacterised conserved protein UCP031279 | UCP031279 | 8 |
IPR016973 | 16,973 | Integral membrane protein SYS1 | Integral_membrane_SYS1 | Family | 950 | false | false | This entry represents SYS1 homologues (hSYS1). hSYS1 is a multi-pass membrane protein found in the Golgi apparatus membrane. hSYS1 appears to be involved in protein trafficking and may serve as a receptor for ARFRP1 (Arf-related protein 1), the human homologues of Arl3p [ ]. Arf family members are GTPases that are cruc... | [
"GO:0000139"
] | [
"Golgi membrane"
] | [
"cellular_component"
] | 1 | [
"PIRSF"
] | [
"PIRSF031402"
] | [
"SYS1_homologue"
] | [
950
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-6811440",
"R-HSA-6811440",
"R-MMU-6811440"
] | [
"REACTOME:R-BTA-6811440",
"REACTOME:R-HSA-6811440",
"REACTOME:R-MMU-6811440"
] | 3 | [] | 0 | [
"PUB00018388",
"PUB00043275"
] | [
"12620189",
"15077113"
] | [
"The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus.",
"Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p."
] | [
2003,
2004
] | 2 | [
"IPR019185"
] | [] | 1 | 0 | 1 | [
"Eukaryota"
] | [
950
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
5,
1,
1,
2,
2,
1,
2
] | 7 | true | Family | Integral membrane protein SYS1 | Integral membrane protein SYS1 | Integral_membrane_SYS1 | 4 |
IPR016974 | 16,974 | Uncharacterised phage-associated protein | Uncharacterised_phage-assoc | Family | 273 | false | false | This entry represents uncharacterised phage-associated proteins. It includes Orf19 from Lactococcus phage 4268. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031475"
] | [
"UCP031475"
] | [
273
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacilli",
"Caudoviricetes"
] | [
244,
29
] | 2 | [] | [] | 0 | true | Family | Uncharacterised phage-associated protein | Uncharacterised phage-associated protein | Uncharacterised_phage-assoc | 1 |
IPR016975 | 16,975 | Cell wall-active antibiotic response protein LiaF | Cell_wall_LiaF | Family | 2,181 | false | false | The LiaRS two-component system is part of the regulatory network orchestrating the cell-envelope stress response in Bacillus subtilis. It responds to perturbations with the cell envelope, especially antibiotics that interfere with the lipid II and undecaprenol cycle, such as bacitracin or vancomycin. LiaRS-dependent re... | [
"GO:0016020"
] | [
"membrane"
] | [
"cellular_component"
] | 1 | [
"PIRSF"
] | [
"PIRSF031509"
] | [
"Cell_wall_LiaF/YvqF"
] | [
2181
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00044105",
"PUB00044106"
] | [
"17660417",
"16816187"
] | [
"LiaRS-dependent gene expression is embedded in transition state regulation in Bacillus subtilis.",
"Regulation of LiaRS-dependent gene expression in bacillus subtilis: identification of inhibitor proteins, regulator binding sites, and target genes of a conserved cell envelope stress-sensing two-component system.... | [
2007,
2006
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
2179,
2
] | 2 | [] | [] | 0 | true | Family | Cell wall-active antibiotic response protein LiaF | Cell wall-active antibiotic response protein LiaF | Cell_wall_LiaF | 7 |
IPR016976 | 16,976 | Uncharacterised conserved protein UCP031601 | UCP031601 | Family | 298 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. However, members contain multiple membrane-spanning regions and are found in association with bacteriocins [ ]. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031601"
] | [
"UCP031601"
] | [
298
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00009668"
] | [
"10589723"
] | [
"Synthesis of lactococcin 972, a bacteriocin produced by Lactococcus lactis IPLA 972, depends on the expression of a plasmid-encoded bicistronic operon."
] | [
1999
] | 1 | [
"IPR006541"
] | [] | 1 | 0 | 1 | [
"Bacteria"
] | [
298
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP031601 | Uncharacterised conserved protein UCP031601 | UCP031601 | 3 |
IPR016977 | 16,977 | Competence protein ComGF | ComGF | Family | 2,601 | false | false | This entry represents Competence protein ComGF (also known as ComG operon protein 6), from Streptococcus pneumoniae, ComGF from Bacillus subtilisand similar proteins from Bacilli. These proteins are required for transformation and DNA binding [ ]. Competence protein ComGF from Streptococcus pneumoniae is required for f... | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM",
"PIRSF"
] | [
"NF041002",
"PF15980",
"PIRSF031611"
] | [
"pilin_ComGF",
"ComGF",
"Competence_ComGF"
] | [
1721,
2599,
634
] | 3 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045992",
"PUB00045993",
"PUB00052316",
"PUB00052317",
"PUB00067657",
"PUB00106112"
] | [
"9422590",
"9723928",
"8901420",
"10361283",
"2507524",
"35004361"
] | [
"All seven comG open reading frames are required for DNA binding during transformation of competent Bacillus subtilis.",
"Cell surface localization and processing of the ComG proteins, required for DNA binding during transformation of Bacillus subtilis.",
"Who's competent and when: regulation of natural genetic... | [
1998,
1998,
1996,
1999,
1989,
2021
] | 6 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
2600,
1
] | 2 | [] | [] | 0 | true | Family | Competence protein ComGF | Competence protein ComGF | ComGF | 2 |
IPR016978 | 16,978 | Putative competence-induced protein Ccs4, streptococcus | Competence-induced_Ccs4_sc | Family | 114 | false | false | These proteins are part of a set in Streptococcus species that undergo late induction by competence pheromone [ ]. There is currently no data that address the function, nor is it known if induction occurs in other species. However, the proteins are predicted to be integral membrane proteins (with several transmembrane ... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031639"
] | [
"Ccs4"
] | [
114
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00035949",
"PUB00052316"
] | [
"14763980",
"8901420"
] | [
"Identification of competence pheromone responsive genes in Streptococcus pneumoniae by use of DNA microarrays.",
"Who's competent and when: regulation of natural genetic competence in bacteria."
] | [
2004,
1996
] | 2 | [
"IPR060756"
] | [] | 1 | 0 | 1 | [
"Streptococcaceae"
] | [
114
] | 1 | [] | [] | 0 | true | Family | Putative competence-induced protein Ccs4, streptococcus | Putative competence-induced protein Ccs4, streptococcus | Competence-induced_Ccs4_sc | 9 |
IPR016979 | 16,979 | Protein of unknown function DUF2129 | DUF2129 | Family | 2,901 | false | false | This is a group of uncharacterised conserved protein from bacteria. | [] | [] | [] | 0 | [
"HAMAP",
"PFAM",
"PIRSF"
] | [
"MF_01126",
"PF09902",
"PIRSF031653"
] | [
"UPF0298",
"DUF2129",
"UCP031653"
] | [
1630,
2901,
2094
] | 3 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"bioreactor metagenome"
] | [
2897,
3,
1
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2129 | Protein of unknown function DUF2129 | DUF2129 | 3 |
IPR016980 | 16,980 | S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted | S-AdoMet-dep_MeTrfase_Alr7345 | Family | 3,233 | false | false | This entry represents proteins predicted to function as S-adenosyl-L-methionine dependent methyltransferases, such as the uncharacterised protein Alr7345 from Anabaena sp. (strain PCC 7120). | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031679"
] | [
"Mtase_Alr7345_prd"
] | [
3233
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Knufia peltigerae",
"ecological metagenomes"
] | [
3185,
1,
47
] | 3 | [] | [] | 0 | true | Family | S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted | S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted | S-AdoMet-dep_MeTrfase_Alr7345 | 9 |
IPR016981 | 16,981 | Transcription regulator, AraC, predicted | Tscrpt_reg_031684_prd | Family | 127 | false | false | This group represents a predicted transcriptional regulator, AraC type. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031684"
] | [
"Txn_reg_031684_prd"
] | [
127
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadota"
] | [
127
] | 1 | [] | [] | 0 | true | Family | Transcription regulator, AraC, predicted | Transcription regulator, AraC, predicted | Tscrpt_reg_031684_prd | 4 |
IPR016983 | 16,983 | Uncharacterised conserved protein UCP031804 | UCP031804 | Family | 2,322 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031804"
] | [
"UCP031804"
] | [
2322
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)",
"Ricinus communis",
"metagenomes"
] | [
2308,
1,
1,
12
] | 4 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP031804 | Uncharacterised conserved protein UCP031804 | UCP031804 | 6 |
IPR016984 | 16,984 | Uncharacterised conserved protein UCP031853 | UCP031853 | Family | 718 | false | false | There is currently no experimental data for members of this group or their homologues. Though they contain a version of the type II restriction endonuclease domain, it lacks the signature P[D]-[D/E]-X-K. It is therefore not clear if members of this group are enzymatically active endonucleases. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031853"
] | [
"UPC031853"
] | [
718
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"metagenomes"
] | [
20,
692,
6
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP031853 | Uncharacterised conserved protein UCP031853 | UCP031853 | 6 |
IPR016985 | 16,985 | Uncharacterised conserved protein UCP031890, Tim44-related | UCP031890_Tim44-rel | Family | 2,510 | false | false | This group consists of bacterial uncharacterised proteins containing a Tim44-like domain ( ). Their function is unknown, but a role in transport seems likely. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031890"
] | [
"UCP031890_transporter_Tim44"
] | [
2510
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR039544"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Symbiodinium necroappetens",
"metagenomes"
] | [
2490,
1,
19
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP031890, Tim44-related | Uncharacterised conserved protein UCP031890, Tim44-related | UCP031890_Tim44-rel | 6 |
IPR016986 | 16,986 | Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL | UCP031982_abhydr | Family | 3,379 | false | false | This group represents a predicted alpha/beta hydrolase, XabL type. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF031982"
] | [
"UCP031982_abhydr"
] | [
3379
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
3373,
3,
3
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL | Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL | UCP031982_abhydr | 3 |
IPR016987 | 16,987 | Uncharacterised conserved protein UCP023238 | UCP023238 | Family | 297 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032038"
] | [
"UCP023238"
] | [
297
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"marine sediment metagenome"
] | [
296,
1
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP023238 | Uncharacterised conserved protein UCP023238 | UCP023238 | 5 |
IPR016988 | 16,988 | Uncharacterised conserved protein UCP032086 | UCP032086 | Family | 528 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032086"
] | [
"UCP032086"
] | [
528
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
476,
52
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032086 | Uncharacterised conserved protein UCP032086 | UCP032086 | 4 |
IPR016989 | 16,989 | ATP synthase protein I, alphaproteobacterial | Atp1_alphaprobac | Family | 2,130 | false | false | Transport ATPases can be lumped into four distinct types, P, F, V, and ABC. The transport ATPase field is paving the way for nanotechnology focused on nano-motors using the F-type ATPases (F(0)F(1)). When these ATPases are driven in reverse by a proton gradient, they have the capacity to interconvert electrochemical en... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032126"
] | [
"F0F1_ATP_synthase_subunit_I"
] | [
2130
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00043510"
] | [
"18175209"
] | [
"Transport ATPases into the year 2008: a brief overview related to types, structures, functions and roles in health and disease."
] | [
2007
] | 1 | [
"IPR032820"
] | [] | 1 | 0 | 1 | [
"Diploscapter pachys",
"Pseudomonadati",
"metagenomes"
] | [
1,
2095,
34
] | 3 | [] | [] | 0 | true | Family | ATP synthase protein I, alphaproteobacterial | ATP synthase protein I, alphaproteobacterial | Atp1_alphaprobac | 6 |
IPR016990 | 16,990 | Uncharacterised conserved protein UCP032162, transmembrane | UCP032162_TM | Family | 1,686 | false | false | There is currently no experimental data for members of this group of proteins or their homologues, nor do they exhibit features indicative of any function. However, they are predicted to be integral membrane proteins. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032162"
] | [
"UCP032162_imp"
] | [
1686
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR019253"
] | [] | 1 | 0 | 1 | [
"Pseudomonadota",
"metagenomes"
] | [
1679,
7
] | 2 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032162, transmembrane | Uncharacterised conserved protein UCP032162, transmembrane | UCP032162_TM | 4 |
IPR016991 | 16,991 | Protein of unknown function UCP032178 | UCP032178 | Family | 1,208 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. However, they may be membrane-anchored (based on transmembrane segment prediction). | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032178"
] | [
"UCP032178"
] | [
1208
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR007383"
] | [] | 1 | 0 | 1 | [
"Bacillati",
"human gut metagenome"
] | [
1207,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function UCP032178 | Protein of unknown function UCP032178 | UCP032178 | 9 |
IPR016992 | 16,992 | Uncharacterised conserved protein UCP032209 | UCP032209 | Family | 328 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032209"
] | [
"UCP032209"
] | [
328
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR012441"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Halobacteriales",
"ecological metagenomes",
"virus sp. ct6zJ3"
] | [
318,
6,
3,
1
] | 4 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032209 | Uncharacterised conserved protein UCP032209 | UCP032209 | 5 |
IPR016993 | 16,993 | Predicted glycerophosphotransferase, SA2157 type | SA2157_glycerophostrnsf | Family | 93 | false | false | This group represents a predicted glycerophosphotransferase, SA2157 type. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032341"
] | [
"UCP032341_glycerophostrnsf"
] | [
93
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [
"IPR007554"
] | [] | 1 | 0 | 1 | [
"Bacillales"
] | [
93
] | 1 | [] | [] | 0 | true | Family | Predicted glycerophosphotransferase, SA2157 type | Predicted glycerophosphotransferase, SA2157 type | SA2157_glycerophostrnsf | 2 |
IPR016994 | 16,994 | VraC | VraC | Family | 140 | false | false | This group represents a group of proteins mainly found in Staphylococcus species, including VraC, which is presumed to form a complex with VraA and VraB [ ]. This protein contributes to vancomycin resistance [ ]. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF27762",
"PIRSF032370"
] | [
"VraC",
"UCP032370_VraC"
] | [
140,
33
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00042647",
"PUB00162560"
] | [
"10708580",
"33948657"
] | [
"Identification of the up- and down-regulated genes in vancomycin-resistant Staphylococcus aureus strains Mu3 and Mu50 by cDNA differential hybridization method.",
"VraCP regulates cell wall metabolism and antibiotic resistance in vancomycin-intermediate Staphylococcus aureus strain Mu50."
] | [
2000,
2021
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
140
] | 1 | [] | [] | 0 | true | Family | VraC | VraC | VraC | 3 |
IPR016995 | 16,995 | Dimeric dUTPase Dut-like | Dimeric_Dut-like | Family | 137 | false | false | This entry represents a family of proteins from tailed bacteriophages and bacterial prophages, including the phage dimeric dUTPase (Dut) from Staphylococcus virus 69 ( ). This protein, which interacts with the Staphylococcus aureus pathogenicity island SaPIbov1 Stl repressor from this bacteria, shows a homodimeric asse... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032436"
] | [
"UCP032436"
] | [
137
] | 1 | [] | [] | [] | 0 | [
"5mil",
"5myd",
"5myf",
"5myi",
"6h4b"
] | 5 | [
"PUB00100880",
"PUB00100881",
"PUB00100882"
] | [
"28826473",
"31417084",
"28892519"
] | [
"Pirating conserved phage mechanisms promotes promiscuous staphylococcal pathogenicity island transfer.",
"The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.",
"Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilizatio... | [
2017,
2019,
2017
] | 3 | [
"IPR014871"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Viruses"
] | [
73,
64
] | 2 | [] | [] | 0 | true | Family | Dimeric dUTPase Dut-like | Dimeric dUTPase Dut-like | Dimeric_Dut-like | 1 |
IPR016996 | 16,996 | Uncharacterised conserved protein UCP032441 | UCP032441 | Family | 84 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032441"
] | [
"UCP032441"
] | [
84
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
84
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032441 | Uncharacterised conserved protein UCP032441 | UCP032441 | 2 |
IPR016997 | 16,997 | Uncharacterised conserved protein UCP032442 | UCP032442 | Family | 1,417 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032442"
] | [
"UCP032442"
] | [
1417
] | 1 | [] | [] | [] | 0 | [
"3erv"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"bioreactor metagenome"
] | [
1413,
3,
1
] | 3 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032442 | Uncharacterised conserved protein UCP032442 | UCP032442 | 3 |
IPR016998 | 16,998 | HTH-type transcriptional regulator Rot | Rot | Family | 48 | false | false | This group represents the HTH transcriptional regulator Rot. Rot (repressor of toxin) is a member of the Sar family of transcriptional factors of Staphylococcus aureus. It is a global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence [ , ]. | [
"GO:0003700"
] | [
"DNA-binding transcription factor activity"
] | [
"molecular_function"
] | 1 | [
"PIRSF"
] | [
"PIRSF032474"
] | [
"TF_HTH_Rot"
] | [
48
] | 1 | [] | [] | [] | 0 | [
"4q77",
"4rbr"
] | 2 | [
"PUB00067869",
"PUB00067870"
] | [
"10809700",
"12511508"
] | [
"Identification, cloning, and initial characterization of rot, a locus encoding a regulator of virulence factor expression in Staphylococcus aureus.",
"Global regulation of Staphylococcus aureus genes by Rot."
] | [
2000,
2003
] | 2 | [
"IPR039422"
] | [] | 1 | 0 | 1 | [
"Staphylococcus",
"human gut metagenome"
] | [
47,
1
] | 2 | [] | [] | 0 | true | Family | HTH-type transcriptional regulator Rot | HTH-type transcriptional regulator Rot | Rot | 3 |
IPR016999 | 16,999 | L-serine kinase SbnI-like | SbnI-like | Family | 166 | false | false | This entry represents a family of bacterial proteins which includes L-serine kinase SbnI. SbnI acts as a heme-dependent transcriptional regulator of the sbn locus, which is involved in Staphyloferrin B biosynthesis. SbnI uses ATP to phosphorylate L-serine, producing O-phospho-L-serine and ADP [ ]. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032543"
] | [
"UCP032543_ParB-like"
] | [
166
] | 1 | [] | [] | [] | 0 | [
"5ujd",
"5uje",
"6nr6"
] | 3 | [
"PUB00092872"
] | [
"29483190"
] | [
"SbnI is a free serine kinase that generates O -phospho-l-serine for staphyloferrin B biosynthesis in Staphylococcus aureus."
] | [
2018
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
166
] | 1 | [] | [] | 0 | true | Family | L-serine kinase SbnI-like | L-serine kinase SbnI-like | SbnI-like | 2 |
IPR017000 | 17,000 | Membrane-anchored ubiquitin-fold protein | MUB | Family | 3,252 | false | false | Ubiquitin-fold proteins are an important class of eukaryotic post-translational modifiers [ , ]. They are generally short proteins (less than 200 amino acids) which contain the core β-grasp fold (also known as the ubiquitin fold) and a C-terminal extension which enables their attachment to other proteins through the te... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032572"
] | [
"MUB"
] | [
3252
] | 1 | [] | [] | [] | 0 | [
"1se9",
"1wgh",
"2gow",
"4x57"
] | 4 | [
"PUB00043568",
"PUB00043569",
"PUB00076959",
"PUB00076960"
] | [
"16831869",
"12826404",
"21345795",
"10375635"
] | [
"MUBs, a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation.",
"A superfamily of protein tags: ubiquitin, SUMO and related modifiers.",
"Arabidopsis membrane-anchored ubiquitin-fold (MUB) proteins localize a specific subset of ubiquitin-conjugating (E2) enzymes to the plasma memb... | [
2006,
2003,
2011,
1999
] | 4 | [
"IPR040015"
] | [] | 1 | 0 | 1 | [
"Eukaryota"
] | [
3252
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
17,
1,
3,
1,
3,
5,
1,
14
] | 8 | true | Family | Membrane-anchored ubiquitin-fold protein | Membrane-anchored ubiquitin-fold protein | MUB | 4 |
IPR017001 | 17,001 | Peptidase S53, physarolisin II, archaeal-type | Pept_S53_physarolisin-II_arc | Family | 150 | false | false | This entry contains serine peptidases belonging to the MEROPS peptidase family S53 (sedolisin family, clan SB). The peptidases all derive from archaeal species but are related to physarolisin II, which is cold-adapted serine-carboxyl peptidase, encoded by the php gene in Physarum polycephalum (Slime mold) [ ]. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032623"
] | [
"Peptidase_SSO2181_prd"
] | [
150
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00042740"
] | [
"12832065"
] | [
"The Physarum polycephalum php gene encodes a unique cold-adapted serine-carboxyl peptidase, physarolisin II."
] | [
2003
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea"
] | [
150
] | 1 | [] | [] | 0 | true | Family | Peptidase S53, physarolisin II, archaeal-type | Peptidase S53, physarolisin II, archaeal-type | Pept_S53_physarolisin-II_arc | 9 |
IPR017002 | 17,002 | Glycoside hydrolase, family 57, Saci1162, predicted | Glyco_hydro_57_Saci1162_prd | Family | 24 | false | false | O-Glycosyl hydrolases ( ) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [ ,... | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032656"
] | [
"Glycosyl_Ohase_Saci_1162_prd"
] | [
24
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00004870",
"PUB00005266"
] | [
"7624375",
"8535779"
] | [
"Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases.",
"Structures and mechanisms of glycosyl hydrolases."
] | [
1995,
1995
] | 2 | [
"IPR052046"
] | [] | 1 | 0 | 1 | [
"Sulfolobaceae"
] | [
24
] | 1 | [] | [] | 0 | true | Family | Glycoside hydrolase, family 57, Saci1162, predicted | Glycoside hydrolase, family 57, Saci1162, predicted | Glyco_hydro_57_Saci1162_prd | 3 |
IPR017003 | 17,003 | Uncharacterised conserved protein UCP032675 | UCP032675 | Family | 30 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032675"
] | [
"UCP032675"
] | [
30
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Thermoproteota"
] | [
30
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032675 | Uncharacterised conserved protein UCP032675 | UCP032675 | 8 |
IPR017004 | 17,004 | Uncharacterised conserved protein UCP032676, PqqC | UCP032676_PqqC | Family | 39 | false | false | This group represents an uncharacterised protein with PqqC domain. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032676"
] | [
"UCP032676_PQQC"
] | [
39
] | 1 | [] | [] | [] | 0 | [
"4lqx"
] | 1 | [] | [] | [] | [] | 0 | [
"IPR039068"
] | [] | 1 | 0 | 1 | [
"Archaea"
] | [
39
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032676, PqqC | Uncharacterised conserved protein UCP032676, PqqC | UCP032676_PqqC | 2 |
IPR017006 | 17,006 | Uncharacterised conserved protein UCP032756 | UCP032756 | Family | 118 | false | false | There is currently no experimental data for members of this group or their homologues, nor do they exhibit features indicative of any function. Members are mainly found in clostridia. | [] | [] | [] | 0 | [
"PFAM",
"PIRSF"
] | [
"PF10051",
"PIRSF032756"
] | [
"DUF2286",
"UCP032756"
] | [
118,
50
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Thermoproteati"
] | [
118
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032756 | Uncharacterised conserved protein UCP032756 | UCP032756 | 9 |
IPR017007 | 17,007 | Uncharacterised conserved protein UCP032762 | UCP032762 | Family | 40 | false | false | This uncharacterised family is found in Archaea, mainly in Sulfolobus species. | [] | [] | [] | 0 | [
"PIRSF"
] | [
"PIRSF032762"
] | [
"UCP032762"
] | [
40
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Sulfolobaceae"
] | [
40
] | 1 | [] | [] | 0 | true | Family | Uncharacterised conserved protein UCP032762 | Uncharacterised conserved protein UCP032762 | UCP032762 | 4 |
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