interpro_id
string
interpro_numeric_id
int64
name
string
short_name
string
entry_type
string
protein_count
int64
is_llm
bool
is_llm_reviewed
bool
abstract
string
go_ids
list
go_terms
list
go_categories
list
go_count
int64
member_databases
list
member_accessions
list
member_names
list
member_protein_counts
list
member_count
int64
external_databases
list
external_accessions
list
external_xrefs
list
external_xref_count
int64
pdb_ids
list
structure_count
int64
publication_ids
list
pubmed_ids
list
publication_titles
list
publication_years
list
publication_count
int64
parent_ids
list
child_ids
list
parent_count
int64
child_count
int64
tree_depth
float64
taxonomy_names
list
taxonomy_protein_counts
list
taxonomy_count
int64
key_species_names
list
key_species_protein_counts
list
key_species_count
int64
in_entry_list
bool
entry_list_type
string
entry_list_name
string
names_dat_name
string
short_names_dat_name
string
split_bucket
int64
IPR025025
25,025
Protein of unknown function DUF3914
DUF3914
Family
179
false
false
This family of proteins is functionally uncharacterised. There are two conserved sequence motifs: KFDIR and DLW.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13053" ]
[ "DUF3914" ]
[ 179 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus" ]
[ 179 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3914
Protein of unknown function DUF3914
DUF3914
4
IPR025026
25,026
Protein of unknown function DUF3915
DUF3915
Family
193
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13054" ]
[ "DUF3915" ]
[ 193 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Eukaryota" ]
[ 176, 17 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF3915
Protein of unknown function DUF3915
DUF3915
2
IPR025027
25,027
Protein of unknown function DUF3917
DUF3917
Family
133
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13055" ]
[ "DUF3917" ]
[ 133 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus" ]
[ 133 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3917
Protein of unknown function DUF3917
DUF3917
1
IPR025029
25,029
Protein of unknown function DUF3918
DUF3918
Family
364
false
false
This family of proteins is functionally uncharacterised. There are two completely conserved residues (G and R) that may be functionally important.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13056" ]
[ "DUF3918" ]
[ 364 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales", "Peronospora effusa" ]
[ 363, 1 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF3918
Protein of unknown function DUF3918
DUF3918
6
IPR025030
25,030
Domain of unknown function DUF3950
DUF3950
Domain
754
false
false
This presumed domain is functionally uncharacterised. It is approximately 30 amino acids in length and contains a conserved NFS sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13132" ]
[ "DUF3950" ]
[ 754 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Caudoviricetes", "Eukaryota" ]
[ 735, 17, 2 ]
3
[ "Escherichia coli (strain K12)" ]
[ 2 ]
1
true
Domain
Domain of unknown function DUF3950
Domain of unknown function DUF3950
DUF3950
9
IPR025031
25,031
Protein of unknown function DUF3919
DUF3919
Family
336
false
false
This family of proteins is functionally uncharacterised. There is a conserved YLNG sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13057" ]
[ "DUF3919" ]
[ 336 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Strongyloides venezuelensis" ]
[ 335, 1 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF3919
Protein of unknown function DUF3919
DUF3919
4
IPR025032
25,032
Protein of unknown function DUF3949
DUF3949
Family
402
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13133" ]
[ "DUF3949" ]
[ 402 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota" ]
[ 402 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3949
Protein of unknown function DUF3949
DUF3949
8
IPR025033
25,033
Protein of unknown function DUF3920
DUF3920
Family
210
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13058" ]
[ "DUF3920" ]
[ 210 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae" ]
[ 210 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3920
Protein of unknown function DUF3920
DUF3920
5
IPR025034
25,034
Protein of unknown function DUF3948
DUF3948
Family
639
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13134" ]
[ "DUF3948" ]
[ 639 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 639 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3948
Protein of unknown function DUF3948
DUF3948
7
IPR025035
25,035
Protein of unknown function DUF3922
DUF3922
Family
177
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13059" ]
[ "DUF3922" ]
[ 177 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus" ]
[ 177 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3922
Protein of unknown function DUF3922
DUF3922
3
IPR025036
25,036
Protein of unknown function DUF3921
DUF3921
Family
145
false
false
This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. External database links
[]
[]
[]
0
[ "PFAM" ]
[ "PF13060" ]
[ "DUF3921" ]
[ 145 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae" ]
[ 145 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3921
Protein of unknown function DUF3921
DUF3921
9
IPR025037
25,037
Protein of unknown function DUF3923
DUF3923
Family
559
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13061" ]
[ "DUF3923" ]
[ 559 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 559 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3923
Protein of unknown function DUF3923
DUF3923
7
IPR025038
25,038
Protein of unknown function DUF3924
DUF3924
Family
124
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13062" ]
[ "DUF3924" ]
[ 124 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 124 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3924
Protein of unknown function DUF3924
DUF3924
5
IPR025040
25,040
Protein of unknown function DUF3984
DUF3984
Family
1,029
false
false
This family of proteins is currently functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13136" ]
[ "DUF3984" ]
[ 1029 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1029 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 1 ]
1
true
Family
Protein of unknown function DUF3984
Protein of unknown function DUF3984
DUF3984
9
IPR025041
25,041
Protein of unknown function DUF3983
DUF3983
Family
205
false
false
This family of proteins is functionally uncharacterised. Proteins in this family contain a conserved AWRN sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13137" ]
[ "DUF3983" ]
[ 205 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae", "Caudoviricetes" ]
[ 190, 15 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF3983
Protein of unknown function DUF3983
DUF3983
3
IPR025043
25,043
Domain of unknown function DUF3981
DUF3981
Domain
192
false
false
This presumed domain, approximately 110 amino acids in length, is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13139" ]
[ "DUF3981" ]
[ 192 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 192 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF3981
Domain of unknown function DUF3981
DUF3981
7
IPR025044
25,044
Domain of unknown function DUF3980
DUF3980
Domain
177
false
false
This presumed domain, approximately 90 amino acids in length, is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13140" ]
[ "DUF3980" ]
[ 177 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae" ]
[ 177 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF3980
Domain of unknown function DUF3980
DUF3980
2
IPR025045
25,045
Protein of unknown function DUF3979
DUF3979
Family
169
false
false
This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria. Proteins in this family are approximately 120 amino acids in length.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13141" ]
[ "DUF3979" ]
[ 169 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae" ]
[ 169 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3979
Protein of unknown function DUF3979
DUF3979
7
IPR025046
25,046
Domain of unknown function DUF3960
DUF3960
Domain
173
false
false
This presumed domain, typically between 72 and 89 amino acids in length, is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13142" ]
[ "DUF3960" ]
[ 173 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae" ]
[ 173 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF3960
Domain of unknown function DUF3960
DUF3960
5
IPR025047
25,047
Protein of unknown function DUF3986
DUF3986
Family
464
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13143" ]
[ "DUF3986" ]
[ 464 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota", "Funneliformis caledonium" ]
[ 461, 3 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF3986
Protein of unknown function DUF3986
DUF3986
6
IPR025049
25,049
Fimbrillin-like 1
Mfa-like_1
Family
5,971
false
false
A family of putative fimbrillin proteins found by clustering human gut metagenomic sequences [ ]. Analysis of structural comparisons shows this family to be part of the FimbA (CL0450) superfamily of adhesin components or fimbrillins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13149" ]
[ "Mfa_like_1" ]
[ 5971 ]
1
[]
[]
[]
0
[ "3sy6", "3t2l", "3ufi", "4dgu", "4eps", "4k4k", "4qb7" ]
7
[ "PUB00055601" ]
[ "20532204" ]
[ "Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families." ]
[ 2010 ]
1
[]
[]
0
0
null
[ "Bacteria", "Streblomastix strix", "metagenomes" ]
[ 5870, 2, 99 ]
3
[]
[]
0
true
Family
Fimbrillin-like 1
Fimbrillin-like 1
Mfa-like_1
6
IPR025051
25,051
Protein of unknown function DUF3990
DUF3990
Family
2,155
false
false
This entry represents a family of uncharacterised proteins that was originally found by clustering human gut metagenomic sequences [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF13151" ]
[ "DUF3990" ]
[ 2155 ]
1
[]
[]
[]
0
[]
0
[ "PUB00055601" ]
[ "20532204" ]
[ "Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families." ]
[ 2010 ]
1
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "Methanobacteriati", "unclassified Caudoviricetes", "unclassified sequences" ]
[ 2006, 99, 6, 5, 39 ]
5
[]
[]
0
true
Family
Protein of unknown function DUF3990
Protein of unknown function DUF3990
DUF3990
7
IPR025052
25,052
Domain of unknown function DUF3967
DUF3967
Domain
796
false
false
This presumed domain is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13152" ]
[ "DUF3967" ]
[ 796 ]
1
[]
[]
[]
0
[ "7c7y" ]
1
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus phage Deep-Purple", "Bacteria", "Rhizophagus irregularis (strain DAOM 197198w)" ]
[ 1, 794, 1 ]
3
[]
[]
0
true
Domain
Domain of unknown function DUF3967
Domain of unknown function DUF3967
DUF3967
8
IPR025053
25,053
Protein of unknown function DUF3985
DUF3985
Family
110
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13153" ]
[ "DUF3985" ]
[ 110 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus" ]
[ 110 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3985
Protein of unknown function DUF3985
DUF3985
3
IPR025054
25,054
Domain of unknown function DUF3991
DUF3991
Domain
3,004
false
false
The function is this domain is not known. It is often associated with a Toprim (topoisomerase-primase) domain ( ).
[]
[]
[]
0
[ "PFAM" ]
[ "PF13154" ]
[ "DUF3991" ]
[ 3004 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Chiloscyllium punctatum", "unclassified sequences" ]
[ 2964, 1, 39 ]
3
[]
[]
0
true
Domain
Domain of unknown function DUF3991
Domain of unknown function DUF3991
DUF3991
2
IPR025055
25,055
Endospore appendages core
Ena_core
Domain
934
false
false
The surface of Bacillus and Clostridium endospores is decorated with long filamentous endospores appendages that resemble pili from Gram-negative and Gram-positive bacteria. They show two morphologies, the main or Staggered-type (S-Ena) which accounts for 90% of the fibres, and the Ladder-like (L-Ena) which is smaller ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF13157" ]
[ "Enas" ]
[ 934 ]
1
[]
[]
[]
0
[ "7a02", "8pdz", "9i0y" ]
3
[ "PUB00098173" ]
[ "34031903" ]
[ "Endospore Appendages: a novel pilus superfamily from the endospores of pathogenic Bacilli." ]
[ 2021 ]
1
[]
[]
0
0
null
[ "Bacteria", "bioreactor metagenome" ]
[ 933, 1 ]
2
[]
[]
0
true
Domain
Endospore appendages core
Endospore appendages core
Ena_core
8
IPR025056
25,056
Protein of unknown function DUF3993
DUF3993
Family
339
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13158" ]
[ "DUF3993" ]
[ 339 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales" ]
[ 339 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3993
Protein of unknown function DUF3993
DUF3993
9
IPR025057
25,057
Domain of unknown function DUF3994
DUF3994
Domain
305
false
false
This domain is found at the C-terminal of a group of proteins from Bacillus that have at the N-terminal. Members are functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13159" ]
[ "DUF3994" ]
[ 305 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota" ]
[ 305 ]
1
[]
[]
0
true
Domain
Domain of unknown function DUF3994
Domain of unknown function DUF3994
DUF3994
7
IPR025058
25,058
Protein of unknown function DUF3995
DUF3995
Family
2,396
false
false
This family of proteins is functionally uncharacterised. Proteins in this family are typically between 138 and 149 amino acids in length and contain two completely conserved residues (W and P) that may be functionally important.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13160" ]
[ "DUF3995" ]
[ 2396 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Halobacteriales", "Ricinus communis", "metagenomes" ]
[ 2368, 13, 1, 14 ]
4
[]
[]
0
true
Family
Protein of unknown function DUF3995
Protein of unknown function DUF3995
DUF3995
9
IPR025059
25,059
Protein of unknown function DUF3997
DUF3997
Family
292
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13162" ]
[ "DUF3997" ]
[ 292 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Opisthokonta", "unclassified sequences" ]
[ 288, 2, 2 ]
3
[]
[]
0
true
Family
Protein of unknown function DUF3997
Protein of unknown function DUF3997
DUF3997
3
IPR025060
25,060
Protein of unknown function DUF3999
DUF3999
Family
1,920
false
false
This family of proteins is functionally uncharacterised. Proteins in this family are typically between 440 and 470 amino acids in length and contain a single completely conserved residue D that may be functionally important.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13163" ]
[ "DUF3999" ]
[ 1920 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "ecological metagenomes" ]
[ 1908, 4, 8 ]
3
[]
[]
0
true
Family
Protein of unknown function DUF3999
Protein of unknown function DUF3999
DUF3999
6
IPR025061
25,061
Diedel
Diedel
Family
193
false
false
Diedel (die) was identified as an insect immune response protein. It is up-regulated after a septic injury and may act as a negative regulator of the JAK/STAT signalling pathway [ ]. Its homologues can be found in Drosophila and Acyrtosiphon pisum. Interestingly, the orthologues of the die gene are present in the genom...
[]
[]
[]
0
[ "PFAM" ]
[ "PF13164" ]
[ "Diedel" ]
[ 193 ]
1
[]
[]
[]
0
[ "3zzo", "3zzr" ]
2
[ "PUB00078735", "PUB00078736" ]
[ "22442689", "26739560" ]
[ "Crystal structure of Diedel, a marker of the immune response of Drosophila melanogaster.", "Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila." ]
[ 2012, 2016 ]
2
[]
[]
0
0
null
[ "Eukaryota", "Viruses" ]
[ 175, 18 ]
2
[ "Drosophila melanogaster" ]
[ 9 ]
1
true
Family
Diedel
Diedel
Diedel
3
IPR025062
25,062
Protein of unknown function DUF4003
DUF4003
Family
1,030
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13170" ]
[ "DUF4003" ]
[ 1030 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "bioreactor metagenome" ]
[ 1025, 5 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF4003
Protein of unknown function DUF4003
DUF4003
6
IPR025063
25,063
Protein of unknown function DUF4004
DUF4004
Family
828
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13171" ]
[ "DUF4004" ]
[ 828 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Methanobacterium", "Phytophthora kernoviae 00238/432", "unclassified sequences" ]
[ 818, 6, 1, 3 ]
4
[]
[]
0
true
Family
Protein of unknown function DUF4004
Protein of unknown function DUF4004
DUF4004
6
IPR025064
25,064
Domain of unknown function DUF4005
DUF4005
Domain
11,487
false
false
This domain is found towards the C terminus of a number of plant IQ domain-containing proteins. These proteins may be involved in cooperative interactions with calmodulins or calmodulin-like proteins, and may associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13178" ]
[ "DUF4005" ]
[ 11487 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Embryophyta", "Limnospira" ]
[ 11485, 2 ]
2
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 100, 39, 77 ]
3
true
Domain
Domain of unknown function DUF4005
Domain of unknown function DUF4005
DUF4005
6
IPR025066
25,066
Coiled-coil domain-containing protein 174-like
CCDC174-like
Family
3,874
false
false
This entry represents CCDC174 and related proteins from animals, fungi and plants. CCDC174 is a ubiquitous protein which is restricted to the cell nucleus and co-localises with EIF4A3 [ ]. Mutations in this gene have been linked to a syndrome characterised by hypotonia (low muscle tone) and psychomotor developmental de...
[]
[]
[]
0
[ "PANTHER" ]
[ "PTHR15885" ]
[ "" ]
[ 3874 ]
1
[]
[]
[]
0
[]
0
[ "PUB00098151" ]
[ "26358778" ]
[ "CDC174, a novel component of the exon junction complex whose mutation underlies a syndrome of hypotonia and psychomotor developmental delay." ]
[ 2015 ]
1
[]
[]
0
0
null
[ "Eukaryota" ]
[ 3874 ]
1
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Schizosaccharomyces pombe (stra...
[ 2, 1, 2, 1, 3, 5, 1, 2, 4, 1, 7 ]
11
true
Family
Coiled-coil domain-containing protein 174-like
Coiled-coil domain-containing protein 174-like
CCDC174-like
5
IPR025067
25,067
Protein of unknown function DUF4079
DUF4079
Family
2,544
false
false
This is an uncharacterised family of proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13301" ]
[ "DUF4079" ]
[ 2544 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "marine sediment metagenome" ]
[ 2, 1222, 1319, 1 ]
4
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 7, 7, 7 ]
3
true
Family
Protein of unknown function DUF4079
Protein of unknown function DUF4079
DUF4079
4
IPR025068
25,068
Protein of unknown function DUF3937
DUF3937
Family
143
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13073" ]
[ "DUF3937" ]
[ 143 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 143 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3937
Protein of unknown function DUF3937
DUF3937
8
IPR025069
25,069
Cleavage and polyadenylation specificity factor 2, C-terminal
Cpsf2_C
Domain
4,329
false
false
This domain lies at the C terminus of many fungal and plant cleavage and polyadenylation specificity factor subunit 2 proteins. The exact function of the domain is not known, but is likely to function as a binding domain for the protein within the overall CPSF complex [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF13299" ]
[ "CPSF100_C" ]
[ 4329 ]
1
[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...
[ "R-BTA-159231", "R-BTA-72187", "R-BTA-72203", "R-BTA-73856", "R-BTA-77595", "R-CEL-72187", "R-CEL-72203", "R-CEL-73856", "R-CEL-77595", "R-DDI-77595", "R-DME-159231", "R-DME-72187", "R-DME-72203", "R-DME-73856", "R-DME-77595", "R-HSA-159231", "R-HSA-72187", "R-HSA-72203", "R-HSA-...
[ "REACTOME:R-BTA-159231", "REACTOME:R-BTA-72187", "REACTOME:R-BTA-72203", "REACTOME:R-BTA-73856", "REACTOME:R-BTA-77595", "REACTOME:R-CEL-72187", "REACTOME:R-CEL-72203", "REACTOME:R-CEL-73856", "REACTOME:R-CEL-77595", "REACTOME:R-DDI-77595", "REACTOME:R-DME-159231", "REACTOME:R-DME-72187", "R...
28
[ "6urg", "6v4x", "8ba1" ]
3
[ "PUB00057294" ]
[ "19748916" ]
[ "Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies." ]
[ 2009 ]
1
[]
[]
0
0
null
[ "Eukaryota" ]
[ 4329 ]
1
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...
[ 4, 1, 3, 1, 4, 1, 1, 1, 4, 1, 1, 6 ]
12
true
Domain
Cleavage and polyadenylation specificity factor 2, C-terminal
Cleavage and polyadenylation specificity factor 2, C-terminal
Cpsf2_C
6
IPR025071
25,071
Protein of unknown function DUF3939
DUF3939
Family
401
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13075" ]
[ "DUF3939" ]
[ 401 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales" ]
[ 401 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3939
Protein of unknown function DUF3939
DUF3939
3
IPR025072
25,072
Fur-regulated basic protein A
Fur_reg_FbpA
Domain
1,143
false
false
This entry represents Uncharacterized protein YebD which is regulated by the ferric uptake regulator protein Fur [ ]. This protein does not regulate the lutABC operon encoding iron-sulphur-containing enzymes necessary for growth on lactate [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF13076" ]
[ "Fur_reg_FbpA" ]
[ 1143 ]
1
[]
[]
[]
0
[]
0
[ "PUB00075677", "PUB00075678" ]
[ "18697947", "22427629" ]
[ "The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.", "The FsrA sRNA and FbpB protein mediate the iron-dependent induction of the Bacillus subtilis lutABC iron-sulfur-containing oxidases." ]
[ 2008, 2012 ]
2
[]
[]
0
0
null
[ "Bacillota", "Caudoviricetes" ]
[ 1135, 8 ]
2
[]
[]
0
true
Domain
Fur-regulated basic protein A
Fur-regulated basic protein A
Fur_reg_FbpA
6
IPR025074
25,074
Protein of unknown function DUF3942
DUF3942
Family
167
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13078" ]
[ "DUF3942" ]
[ 167 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales" ]
[ 167 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3942
Protein of unknown function DUF3942
DUF3942
2
IPR025075
25,075
Protein of unknown function DUF3916
DUF3916
Family
504
false
false
This family of proteins is functionally uncharacterised. There is a single completely conserved residue S that may be functionally important.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13079" ]
[ "DUF3916" ]
[ 504 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "bioreactor metagenome" ]
[ 503, 1 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF3916
Protein of unknown function DUF3916
DUF3916
7
IPR025079
25,079
Domain of unknown function DUF3943
DUF3943
Domain
1,083
false
false
This presumed domain is functionally uncharacterised. It is approximately 110 amino acids in length.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13084" ]
[ "DUF3943" ]
[ 1083 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Russula earlei", "metagenomes" ]
[ 1063, 1, 19 ]
3
[]
[]
0
true
Domain
Domain of unknown function DUF3943
Domain of unknown function DUF3943
DUF3943
6
IPR025080
25,080
Protein of unknown function DUF3959
DUF3959
Family
201
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13105" ]
[ "DUF3959" ]
[ 201 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae" ]
[ 201 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3959
Protein of unknown function DUF3959
DUF3959
3
IPR025081
25,081
Domain of unknown function DUF3961
DUF3961
Domain
180
false
false
This presumed domain is functionally uncharacterised. It is approximately 40 amino acids in length.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13106" ]
[ "DUF3961" ]
[ 180 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae", "Wbetavirus" ]
[ 173, 7 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF3961
Domain of unknown function DUF3961
DUF3961
4
IPR025082
25,082
Protein of unknown function DUF3964
DUF3964
Family
193
false
false
This family of proteins is functionally uncharacterised. There are two conserved sequence motifs: FYF and AFW.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13107" ]
[ "DUF3964" ]
[ 193 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales" ]
[ 193 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF3964
Protein of unknown function DUF3964
DUF3964
8
IPR025083
25,083
Protein of unknown function DUF3969
DUF3969
Family
400
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13108" ]
[ "DUF3969" ]
[ 400 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Staphylococcus phage phiSP44-1" ]
[ 399, 1 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF3969
Protein of unknown function DUF3969
DUF3969
1
IPR025085
25,085
pPIWI_RE module, N-terminal domain
pPIWI_RE_X
Domain
829
false
false
This entry represents a domain N-terminal to the pPIWI_RE domain module. PIWI/Argonaute modules are typically N-terminally fused to the PTND1 and PTND2 domains [ ], pPIWI_RE_X may represent an ancestral version of these domains or represent a N-terminal innovation predating the emergence of PTND1 and PTND2 [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF13111" ]
[ "pPIWI_RE_X" ]
[ 829 ]
1
[]
[]
[]
0
[]
0
[ "PUB00091015", "PUB00091016" ]
[ "24311560", "23758928" ]
[ "New perspectives on the diversification of the RNA interference system: insights from comparative genomics and small RNA sequencing.", "Two novel PIWI families: roles in inter-genomic conflicts in bacteria and Mediator-dependent modulation of transcription in eukaryotes." ]
[ 2014, 2013 ]
2
[]
[]
0
0
null
[ "Bacteria", "bioreactor metagenome" ]
[ 828, 1 ]
2
[]
[]
0
true
Domain
pPIWI_RE module, N-terminal domain
pPIWI_RE module, N-terminal domain
pPIWI_RE_X
7
IPR025086
25,086
SDE2/SF3A3, SAP domain
SDE2/SF3A3_SAP
Domain
4,524
false
false
This is the SAP domain found at the C-terminal of SDE2 and in the middle region of splicing factor 3A subunit 3 (SF3A, also known as noisette) [ , , , ]. SDE2 is both an RNA-binding protein and also a trans-acting adaptor protein that functions to regulate RNA splicing and ribosome biogenesis. SF3A is involved in pre-m...
[]
[]
[]
0
[ "PFAM" ]
[ "PF13297" ]
[ "SDE2_2C" ]
[ 4524 ]
1
[ "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]
[ "R-DRE-72163", "R-HSA-72163", "R-MMU-72163", "R-RNO-72163" ]
[ "REACTOME:R-DRE-72163", "REACTOME:R-HSA-72163", "REACTOME:R-MMU-72163", "REACTOME:R-RNO-72163" ]
4
[ "5z56", "5z57", "5z58", "6ah0", "6ahd", "6ff7", "6qx9", "6y50", "6y53", "6y5q", "7abg", "7abh", "7abi", "7evo", "7n99", "7onb", "7q3l", "7q4o", "7q4p", "7qtt", "7vpx", "8c6j", "8ch6", "8h6e", "8h6j", "8h6k", "8h6l", "8hk1", "8i0p", "8i0r", "8i0s", "8i0t"...
44
[ "PUB00057296", "PUB00094506", "PUB00101924", "PUB00101933", "PUB00101934", "PUB00154351" ]
[ "9528755", "29360106", "30315277", "34365507", "27906959", "35850305" ]
[ "Multiple developmental requirements of noisette, the Drosophila homolog of the U2 snRNP-associated polypeptide SP3a60.", "Structure of the human activated spliceosome in three conformational states.", "Structures of the human pre-catalytic spliceosome and its precursor spliceosome.", "SDE2 is an essential ge...
[ 1998, 2018, 2018, 2021, 2016, 2022 ]
6
[]
[]
0
0
null
[ "Eukaryota" ]
[ 4524 ]
1
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Zea mays" ]
[ 14, 2, 3, 1, 7, 3, 6, 7, 19 ]
9
true
Domain
SDE2/SF3A3, SAP domain
SDE2/SF3A3, SAP domain
SDE2/SF3A3_SAP
3
IPR025088
25,088
Protein of unknown function DUF3970
DUF3970
Family
261
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13113" ]
[ "DUF3970" ]
[ 261 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "human gut metagenome" ]
[ 260, 1 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF3970
Protein of unknown function DUF3970
DUF3970
4
IPR025089
25,089
Protein of unknown function DUF4018
DUF4018
Family
217
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13210" ]
[ "DUF4018" ]
[ 217 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillaceae" ]
[ 217 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4018
Protein of unknown function DUF4018
DUF4018
9
IPR025090
25,090
Protein of unknown function DUF4017
DUF4017
Family
192
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13209" ]
[ "DUF4017" ]
[ 192 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 192 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4017
Protein of unknown function DUF4017
DUF4017
2
IPR025091
25,091
Protein of unknown function DUF4019
DUF4019
Family
1,274
false
false
This family of proteins is functionally uncharacterised. There is a single completely conserved residue E that may be functionally important.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13211" ]
[ "DUF4019" ]
[ 1274 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Opisthokonta", "ecological metagenomes" ]
[ 1266, 2, 6 ]
3
[]
[]
0
true
Family
Protein of unknown function DUF4019
Protein of unknown function DUF4019
DUF4019
6
IPR025092
25,092
Glycosyl hydrolase family 66
Glyco_hydro_66
Family
827
false
false
This family is a set of glycosyl hydrolase enzymes including cycloisomaltooligosaccharide glucanotransferase ([ec:2.4.1.-]) and dextranase ( ) activities.
[]
[]
[]
0
[ "PFAM", "CDD" ]
[ "PF13199", "cd14745" ]
[ "Glyco_hydro_66", "GH66" ]
[ 827, 657 ]
2
[ "EC" ]
[ "3.2.1.11" ]
[ "EC:3.2.1.11" ]
1
[ "3vmn", "3vmo", "3vmp", "3wnk", "3wnl", "3wnm", "3wnn", "3wno", "3wnp", "5axg", "5axh", "5x7g", "5x7h", "8iu8", "8iu9", "8iua", "8iub" ]
17
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Dinophyceae", "metagenomes" ]
[ 806, 7, 14 ]
3
[]
[]
0
true
Family
Glycosyl hydrolase family 66
Glycosyl hydrolase family 66
Glyco_hydro_66
8
IPR025094
25,094
Protein of unknown function DUF4021
DUF4021
Family
212
false
false
This family of proteins is functionally uncharacterised. There is a conserved YGM sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13213" ]
[ "DUF4021" ]
[ 212 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales" ]
[ 212 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4021
Protein of unknown function DUF4021
DUF4021
8
IPR025095
25,095
Protein of unknown function DUF4022
DUF4022
Family
175
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13214" ]
[ "DUF4022" ]
[ 175 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus" ]
[ 175 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4022
Protein of unknown function DUF4022
DUF4022
2
IPR025096
25,096
Protein of unknown function DUF4014
DUF4014
Family
227
false
false
This is a bacterial and viral family of uncharacterised proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13198" ]
[ "DUF4014" ]
[ 227 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes", "Enterobacteriaceae" ]
[ 40, 187 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF4014
Protein of unknown function DUF4014
DUF4014
6
IPR025097
25,097
Protein of unknown function DUF4023
DUF4023
Family
562
false
false
This family of proteins is functionally uncharacterised. There is a conserved KLP sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13215" ]
[ "DUF4023" ]
[ 562 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota", "bioreactor metagenome" ]
[ 561, 1 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF4023
Protein of unknown function DUF4023
DUF4023
1
IPR025099
25,099
Protein of unknown function DUF4024
DUF4024
Family
73
false
false
This family of proteins is functionally uncharacterised. There is a conserved RDE sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13216" ]
[ "DUF4024" ]
[ 73 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus" ]
[ 73 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4024
Protein of unknown function DUF4024
DUF4024
9
IPR025100
25,100
Protein of unknown function DUF4025
DUF4025
Family
652
false
false
This family of proteins is functionally uncharacterised. There is a conserved EGT sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13217" ]
[ "DUF4025" ]
[ 652 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 652 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4025
Protein of unknown function DUF4025
DUF4025
8
IPR025101
25,101
Protein of unknown function DUF4012
DUF4012
Family
3,450
false
false
This is a family of uncharacterised proteins found in archaea and bacteria.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13196" ]
[ "DUF4012" ]
[ 3450 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Acrobeloides nanus", "Bacteria", "Methanobacteriaceae", "unclassified sequences" ]
[ 1, 3307, 74, 68 ]
4
[]
[]
0
true
Family
Protein of unknown function DUF4012
Protein of unknown function DUF4012
DUF4012
9
IPR025102
25,102
DUF4026, N-terminal
DUF4026_N
Domain
377
false
false
This entry represents a domain is found N-terminal in functionally uncharacterised bacterial proteins. This domain is found in association with and , that are located C-terminal.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13218" ]
[ "DUF4026_N" ]
[ 377 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 377 ]
1
[]
[]
0
true
Domain
DUF4026, N-terminal
DUF4026, N-terminal
DUF4026_N
5
IPR025103
25,103
Uncharacterized ATP-dependent helicase MG140, N-terminal domain
DUF4011
Domain
4,217
false
false
This domain is found at the N-terminal of Uncharacterized ATP-dependent helicase MG140 and its homologues from archaea and bacteria. Many members are annotated as being putative DNA helicase-related proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13195" ]
[ "DUF4011" ]
[ 4217 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "metagenomes" ]
[ 142, 4032, 7, 36 ]
4
[]
[]
0
true
Domain
Uncharacterized ATP-dependent helicase MG140, N-terminal domain
Uncharacterized ATP-dependent helicase MG140, N-terminal domain
DUF4011
2
IPR025105
25,105
Domain of unknown function DUF4010
DUF4010
Domain
3,899
false
false
This domain is found in putative membrane proteins from archaea and bacteria.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13194" ]
[ "DUF4010" ]
[ 3899 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Ricinus communis", "unclassified sequences" ]
[ 520, 3307, 1, 71 ]
4
[]
[]
0
true
Domain
Domain of unknown function DUF4010
Domain of unknown function DUF4010
DUF4010
2
IPR025106
25,106
Protein of unknown function DUF4028
DUF4028
Family
150
false
false
This family of proteins is functionally uncharacterised. There are two conserved sequence motifs: IVKI and YVKKWF.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13220" ]
[ "DUF4028" ]
[ 150 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus" ]
[ 150 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4028
Protein of unknown function DUF4028
DUF4028
4
IPR025107
25,107
Protein of unknown function DUF4029
DUF4029
Family
160
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13221" ]
[ "DUF4029" ]
[ 160 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus" ]
[ 160 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4029
Protein of unknown function DUF4029
DUF4029
4
IPR025108
25,108
Protein of unknown function DUF4030
DUF4030
Family
180
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13222" ]
[ "DUF4030" ]
[ 180 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales" ]
[ 180 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4030
Protein of unknown function DUF4030
DUF4030
7
IPR025109
25,109
Domain of unknown function DUF4031
DUF4031
Domain
3,477
false
false
This presumed domain is functionally uncharacterised. It contains a conserved HYD sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13223" ]
[ "DUF4031" ]
[ 3477 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "Viruses", "metagenomes" ]
[ 3330, 6, 60, 81 ]
4
[]
[]
0
true
Domain
Domain of unknown function DUF4031
Domain of unknown function DUF4031
DUF4031
7
IPR025110
25,110
AMP-binding enzyme, C-terminal domain
AMP-bd_C
Domain
382,527
false
false
This is a small domain that is found C-terminal to in ATP-dependent AMP-binding enzymes from eukaryotes, bacteria and archaea, including Acetyl-coenzyme A synthetase (Acs). In Acs, this domain undergoes a large rotation to allow for both half-reaction to occur. It shows a central β-sheet core that is flanked by α-helic...
[]
[]
[]
0
[ "PFAM", "PFAM" ]
[ "PF13193", "PF23024" ]
[ "AMP-binding_C", "AMP-dom_DIP2-like" ]
[ 367813, 15353 ]
2
[ "EC", "GP", "GP", "GP", "GP", "GP", "GP", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOM...
[ "6.2.1", "GenProp1308", "GenProp1452", "GenProp1462", "GenProp1562", "GenProp1572", "GenProp1717", "R-BTA-75876", "R-BTA-77111", "R-BTA-77289", "R-CEL-77111", "R-DDI-2151201", "R-DDI-71384", "R-DDI-77111", "R-DME-71384", "R-DRE-77289", "R-HSA-159418", "R-HSA-177128", "R-HSA-17713...
[ "EC:6.2.1", "GP:GenProp1308", "GP:GenProp1452", "GP:GenProp1462", "GP:GenProp1562", "GP:GenProp1572", "GP:GenProp1717", "REACTOME:R-BTA-75876", "REACTOME:R-BTA-77111", "REACTOME:R-BTA-77289", "REACTOME:R-CEL-77111", "REACTOME:R-DDI-2151201", "REACTOME:R-DDI-71384", "REACTOME:R-DDI-77111", ...
77
[ "1amu", "1ba3", "1lci", "1md9", "1mdb", "1mdf", "1pg3", "1pg4", "1ry2", "1t5d", "1t5h", "1ult", "1v25", "1v26", "2d1q", "2d1r", "2d1s", "2d1t", "2p20", "2p2b", "2p2f", "2p2j", "2p2m", "2p2q", "2qvx", "2qvy", "2qvz", "2qw0", "2v7b", "2vsq", "2vze", "2wd9"...
301
[ "PUB00028100", "PUB00097529" ]
[ "12627952", "27908785" ]
[ "The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A.", "DISCO Interacting Protein 2 regulates axonal bifurcation and guidance of Drosophila mushroom body neurons." ]
[ 2003, 2017 ]
2
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "Sym plasmid", "Viruses", "unclassified sequences" ]
[ 5704, 283000, 90081, 1, 3, 3738 ]
6
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus",...
[ 160, 32, 77, 38, 7, 67, 64, 16, 82, 82, 4, 5, 120 ]
13
true
Domain
AMP-binding enzyme, C-terminal domain
AMP-binding enzyme, C-terminal domain
AMP-bd_C
1
IPR025111
25,111
Domain of unknown function DUF4032
DUF4032
Domain
3,096
false
false
This presumed domain is functionally uncharacterised. It is found in bacteria, and is approximately 170 amino acids in length.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13224" ]
[ "DUF4032" ]
[ 3096 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "metagenomes" ]
[ 2983, 113 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF4032
Domain of unknown function DUF4032
DUF4032
2
IPR025112
25,112
Putative carbohydrate metabolism domain
PCMD
Domain
1,833
false
false
This domain has been suggested to participate in carbohydrate metabolism [ ]. Structural evidence indicates that it might be a carbohydrate binding domain, with or without enzymatic activity. In particular, it has been hypothesised that it might act as a glycoside hydrolase [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF13201" ]
[ "PCMD" ]
[ 1833 ]
1
[]
[]
[]
0
[ "3hbz", "3s30", "4het", "4jrl" ]
4
[ "PUB00061399" ]
[ "20944224" ]
[ "Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 A resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism." ]
[ 2010 ]
1
[]
[]
0
0
null
[ "Bacteria", "metagenomes" ]
[ 1814, 19 ]
2
[]
[]
0
true
Domain
Putative carbohydrate metabolism domain
Putative carbohydrate metabolism domain
PCMD
3
IPR025113
25,113
TRL-like protein family
TRL-like
Family
1,302
false
false
This family includes the TRL protein that is found in a locus that includes several tRNAs. The function of this protein is not known [ ]. The proteins in this family usually have a lipoprotein attachment site at their N terminus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13146" ]
[ "TRL" ]
[ 1302 ]
1
[]
[]
[]
0
[]
0
[ "PUB00057297" ]
[ "10411255" ]
[ "A novel tRNA-associated locus (trl) from Helicobacter pylori is co-transcribed with tRNA(Gly) and reveals genetic diversity." ]
[ 1999 ]
1
[]
[]
0
0
null
[ "Bacteria", "ecological metagenomes" ]
[ 1299, 3 ]
2
[]
[]
0
true
Family
TRL-like protein family
TRL-like protein family
TRL-like
5
IPR025114
25,114
Beta-carotene isomerase D27-like, C-terminal
D27-like_C
Domain
2,194
false
false
Beta-carotene isomerase D27 (also known as Protein DWARF-27) from plants is involved in strigolactones biosynthesis. It is a beta-carotene isomerase that converts all-trans-beta-carotene into 9-cis-beta-carotene, which is cleaved by CCD7 into a 9-cis-configured aldehyde [ , ]. This is an iron-containing protein that lo...
[ "GO:0005506" ]
[ "iron ion binding" ]
[ "molecular_function" ]
1
[ "PFAM" ]
[ "PF13225" ]
[ "D27-like_C" ]
[ 2194 ]
1
[ "EC", "METACYC" ]
[ "5.2.1.14", "PWY-7101" ]
[ "EC:5.2.1.14", "METACYC:PWY-7101" ]
2
[]
0
[ "PUB00088582", "PUB00095645", "PUB00095646" ]
[ "22422982", "22623516", "19470589" ]
[ "The path from β-carotene to carlactone, a strigolactone-like plant hormone.", "The Arabidopsis ortholog of rice DWARF27 acts upstream of MAX1 in the control of plant development by strigolactones.", "DWARF27, an iron-containing protein required for the biosynthesis of strigolactones, regulates rice tiller bud ...
[ 2012, 2012, 2009 ]
3
[]
[]
0
0
null
[ "Bacillati", "Eukaryota" ]
[ 49, 2145 ]
2
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 14, 9, 34 ]
3
true
Domain
Beta-carotene isomerase D27-like, C-terminal
Beta-carotene isomerase D27-like, C-terminal
D27-like_C
5
IPR025115
25,115
Domain of unknown function DUF4034
DUF4034
Domain
1,224
false
false
This presumed domain is functionally uncharacterised. It contains a conserved PRW sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13226" ]
[ "DUF4034" ]
[ 1224 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Knufia peltigerae", "hydrothermal vent metagenome" ]
[ 1222, 1, 1 ]
3
[]
[]
0
true
Domain
Domain of unknown function DUF4034
Domain of unknown function DUF4034
DUF4034
9
IPR025117
25,117
Domain of unknown function DUF4037
DUF4037
Domain
2,600
false
false
This presumed domain is functionally uncharacterised. There is a single completely conserved residue P that may be functionally important.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13228" ]
[ "DUF4037" ]
[ 2600 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "metagenomes" ]
[ 5, 2542, 31, 22 ]
4
[]
[]
0
true
Domain
Domain of unknown function DUF4037
Domain of unknown function DUF4037
DUF4037
8
IPR025120
25,120
Domain of unknown function DUF4047
DUF4047
Domain
208
false
false
This presumed domain is functionally uncharacterised. There are two conserved sequence motifs: TEA and FPKT.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13256" ]
[ "DUF4047" ]
[ 208 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Tritrichomonas musculus" ]
[ 207, 1 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF4047
Domain of unknown function DUF4047
DUF4047
9
IPR025121
25,121
GTPase HflX, N-terminal
GTPase_HflX_N
Domain
28,593
false
false
This domain represents the N-terminal region of GTP-binding HflX-like proteins [ , ]. These proteins interact with the 50S ribosome and are GTPases, hydrolysing GTP/GDP/ATP/ADP [ ]. The N-terminal region is necessary for stability of the whole protein.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13167" ]
[ "GTP-bdg_N" ]
[ 28593 ]
1
[]
[]
[]
0
[ "2qtf", "2qth", "3kxi", "3kxk", "3kxl", "5ady", "5zzm", "7of2", "7of4", "7of6", "7yla", "8a57", "8g31", "8g34", "8g38", "8kab", "8uu7", "8uu8", "8uu9", "8uua", "8vio", "8vk0", "8vk7", "8vki", "8vkw", "8vpk", "8vr4", "8vr8", "8vrl" ]
29
[ "PUB00056761", "PUB00056762", "PUB00057298" ]
[ "19109926", "19824612", "19181811" ]
[ "E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides.", "Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach.", "Properties of HflX, an enigmatic protein from Escherichia coli." ]
[ 2009, 2009, 2009 ]
3
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]
[ 804, 24556, 2706, 527 ]
4
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Zea mays" ]
[ 9, 1, 2, 2, 1, 3, 4, 5, 1, 12 ]
10
true
Domain
GTPase HflX, N-terminal
GTPase HflX, N-terminal
GTPase_HflX_N
6
IPR025122
25,122
Domain of unknown function DUF4048
DUF4048
Domain
1,021
false
false
This presumed domain is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13257" ]
[ "DUF4048" ]
[ 1021 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "saccharomyceta" ]
[ 1021 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]
[ 2 ]
1
true
Domain
Domain of unknown function DUF4048
Domain of unknown function DUF4048
DUF4048
5
IPR025123
25,123
Domain of unknown function DUF4049
DUF4049
Domain
377
false
false
This presumed domain is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13258" ]
[ "DUF4049" ]
[ 377 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Enterobacteriaceae", "human gut metagenome" ]
[ 369, 8 ]
2
[ "Escherichia coli (strain K12)" ]
[ 2 ]
1
true
Domain
Domain of unknown function DUF4049
Domain of unknown function DUF4049
DUF4049
7
IPR025124
25,124
Gag1-like, clamp domain
Gag1-like_clamp
Domain
4,427
false
false
This entry represents a domain found in a group of sequences from fungi and plants, including Gag1 from Saccharomyces cerevisiae (YLR407W), which interacts with Cka2, the fourth subunit of the eukaryotic kinase CK2. Gag1 is organised into three domains: lock, Gag and Clap (this entry). This domain, previously known as ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF13259" ]
[ "clamp_Gag1-like" ]
[ 4427 ]
1
[]
[]
[]
0
[]
0
[ "PUB00153176" ]
[ "37968396" ]
[ "The social and structural architecture of the yeast protein interactome." ]
[ 2023 ]
1
[]
[]
0
0
null
[ "Eukaryota", "Pedobacter yonginense" ]
[ 4426, 1 ]
2
[ "Arabidopsis thaliana", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]
[ 29, 1, 6, 1, 1, 26 ]
6
true
Domain
Gag1-like, clamp domain
Gag1-like, clamp domain
Gag1-like_clamp
2
IPR025126
25,126
Protein of unknown function DUF4052
DUF4052
Family
159
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13261" ]
[ "DUF4052" ]
[ 159 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillati" ]
[ 159 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4052
Protein of unknown function DUF4052
DUF4052
9
IPR025127
25,127
Protein of unknown function DUF4054
DUF4054
Family
2,086
false
false
This family of proteins is functionally uncharacterised. Proteins in this family are found in bacteria and viruses.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13262" ]
[ "DUF4054" ]
[ 2086 ]
1
[]
[]
[]
0
[ "7kln", "8fvh", "8hdr", "8hds", "9b41", "9jlf", "9kmh", "9l01" ]
8
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Fungi", "Stenosarchaea group", "Viruses", "metagenomes" ]
[ 1511, 3, 2, 552, 18 ]
5
[]
[]
0
true
Family
Protein of unknown function DUF4054
Protein of unknown function DUF4054
DUF4054
6
IPR025128
25,128
Poxvirus B22R protein C-terminal domain
Poxvirus_B22R_C_dom
Domain
273
false
false
This domain represents a highly conserved region towards the C terminus of poxvirus proteins from Fowlpox virus, Myxoma virus, Lumpy skin disease, Variola virus and other members of the Poxviridae family of double-stranded, no-RNA stage poxviruses.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13168" ]
[ "Poxvirus_B22R_C" ]
[ 273 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viruses" ]
[ 273 ]
1
[]
[]
0
true
Domain
Poxvirus B22R protein C-terminal domain
Poxvirus B22R protein C-terminal domain
Poxvirus_B22R_C_dom
4
IPR025129
25,129
Domain of unknown function DUF4055
DUF4055
Domain
1,439
false
false
This presumed domain is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13264" ]
[ "DUF4055" ]
[ 1439 ]
1
[]
[]
[]
0
[ "8xb5", "8xb6" ]
2
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]
[ 1045, 4, 369, 21 ]
4
[]
[]
0
true
Domain
Domain of unknown function DUF4055
Domain of unknown function DUF4055
DUF4055
9
IPR025130
25,130
Protein of unknown function DUF4056
DUF4056
Family
840
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13265" ]
[ "DUF4056" ]
[ 840 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "ecological metagenomes" ]
[ 838, 2 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF4056
Protein of unknown function DUF4056
DUF4056
4
IPR025131
25,131
Domain of unknown function DUF4057
DUF4057
Domain
1,905
false
false
This entry represents a domain found in a group of plant proteins, including DNA oxidative demethylase ALKBH2 from Arabidopsis thaliana , a dioxygenase that repairs alkylated DNA containing 1-methyladenine and 1-ethenoadenine by oxidative demethylation [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF13266" ]
[ "DUF4057" ]
[ 1905 ]
1
[]
[]
[]
0
[]
0
[ "PUB00101956" ]
[ "22532610" ]
[ "The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage." ]
[ 2012 ]
1
[]
[]
0
0
null
[ "Heyndrickxia ginsengihumi", "Viridiplantae" ]
[ 1, 1904 ]
2
[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]
[ 27, 12, 49 ]
3
true
Domain
Domain of unknown function DUF4057
Domain of unknown function DUF4057
DUF4057
8
IPR025132
25,132
Protein of unknown function DUF4058
DUF4058
Family
693
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13267" ]
[ "DUF4058" ]
[ 693 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Opisthokonta", "unclassified sequences" ]
[ 683, 5, 5 ]
3
[]
[]
0
true
Family
Protein of unknown function DUF4058
Protein of unknown function DUF4058
DUF4058
3
IPR025133
25,133
Poxvirus B22R protein N-terminal domain
Poxvirus_B22R_N_dom
Domain
256
false
false
This domain represents the highly conserved N-terminal region of poxvirus proteins from Fowlpox virus, Myxoma virus, Lumpy skin disease, Variola virus and other members of the Poxviridae family of double-stranded, no-RNA stage poxviruses.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13169" ]
[ "Poxvirus_B22R_N" ]
[ 256 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Poxviridae" ]
[ 256 ]
1
[]
[]
0
true
Domain
Poxvirus B22R protein N-terminal domain
Poxvirus B22R protein N-terminal domain
Poxvirus_B22R_N_dom
5
IPR025134
25,134
Protein of unknown function DUF4059
DUF4059
Family
391
false
false
This family of proteins is functionally uncharacterised. There is a conserved DKT sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13268" ]
[ "DUF4059" ]
[ 391 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 391 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4059
Protein of unknown function DUF4059
DUF4059
9
IPR025137
25,137
Bacteriophage N4 adsorption protein A, C-terminal
NfrA_C
Domain
1,090
false
false
The function of this domain is unknown, but it is found at the C terminus of bacteriophage N4 adsorption protein A (NfrA) in association with an N-terminal region of Tetratricopeptide (TPR) repeats. NfrA serves as the phage receptor [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF13283" ]
[ "NfrA_C" ]
[ 1090 ]
1
[]
[]
[]
0
[]
0
[ "PUB00057299" ]
[ "8226649" ]
[ "Two overlapping genes encoding membrane proteins required for bacteriophage N4 adsorption." ]
[ 1993 ]
1
[]
[]
0
0
null
[ "Bacteria", "Rhizopus delemar", "metagenomes" ]
[ 1080, 1, 9 ]
3
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Domain
Bacteriophage N4 adsorption protein A, C-terminal
Bacteriophage N4 adsorption protein A, C-terminal
NfrA_C
1
IPR025138
25,138
Domain of unknown function DUF4072
DUF4072
Domain
649
false
false
This short domain of unknown function is normally found at the N terminus of putative phosphoserine phosphatases.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13284" ]
[ "DUF4072" ]
[ 649 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Linnemannia gamsii", "Pseudomonadota", "metagenomes" ]
[ 1, 637, 11 ]
3
[]
[]
0
true
Domain
Domain of unknown function DUF4072
Domain of unknown function DUF4072
DUF4072
3
IPR025140
25,140
Putative 2/3 transmembrane domain holin
Holin_2-3
Family
633
false
false
Holin_2-3 is a putative holins with 2 or 3 transmembrane segments. It consists of many proteobacterial proteins ranging in size from about 70 aas to 120 aas. They have 2 or 3 predicted TMSs. Although some are annotated as phage proteins or holins, none appears to be functionally characterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13272" ]
[ "Holin_2-3" ]
[ 633 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Caudoviricetes", "Puccinia striiformis f. sp. tritici PST-78", "metagenomes" ]
[ 608, 21, 2, 2 ]
4
[]
[]
0
true
Family
Putative 2/3 transmembrane domain holin
Putative 2/3 transmembrane domain holin
Holin_2-3
6
IPR025141
25,141
Domain of unknown function DUF4082
DUF4082
Domain
1,743
false
false
This domain appears to be a parallel β-helix repeated region that is located between successive cadherin domains in some proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13313" ]
[ "DUF4082" ]
[ 1743 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Arthrobacter phage Wildwest", "Bacteria", "Eukaryota", "metagenomes" ]
[ 1, 1726, 4, 12 ]
4
[]
[]
0
true
Domain
Domain of unknown function DUF4082
Domain of unknown function DUF4082
DUF4082
4
IPR025142
25,142
Domain of unknown function DUF4073
DUF4073
Domain
435
false
false
This domain is frequently found at the C terminus of bacterial proteins carrying the metallophosphoesterase domain .
[]
[]
[]
0
[ "PFAM" ]
[ "PF13285" ]
[ "DUF4073" ]
[ 435 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillati", "bioreactor metagenome" ]
[ 434, 1 ]
2
[]
[]
0
true
Domain
Domain of unknown function DUF4073
Domain of unknown function DUF4073
DUF4073
1
IPR025143
25,143
Protein of unknown function DUF4083
DUF4083
Family
468
false
false
This protein family is functionally uncharacterised. Some members are putatively annotated as being MutT/Nudix. However, the characteristic Nudix motif of GX(5)EX(7)REUXEE is absent.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13314" ]
[ "DUF4083" ]
[ 468 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 468 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4083
Protein of unknown function DUF4083
DUF4083
7
IPR025145
25,145
Protein of unknown function DUF4087
DUF4087
Family
437
false
false
This family of proteins is functionally uncharacterised. There is a conserved RCGW sequence motif.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13316" ]
[ "DUF4087" ]
[ 437 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "mine drainage metagenome" ]
[ 436, 1 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF4087
Protein of unknown function DUF4087
DUF4087
7
IPR025146
25,146
Protein of unknown function DUF4088
DUF4088
Family
358
false
false
This family of proteins is functionally uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF13317" ]
[ "DUF4088" ]
[ 358 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Burkholderiales" ]
[ 358 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF4088
Protein of unknown function DUF4088
DUF4088
7
IPR025147
25,147
DNA packaging protein FI
Packaging_FI
Family
767
false
false
This family includes the lambda phage DNA-packaging protein FI [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF14000" ]
[ "Packaging_FI" ]
[ 767 ]
1
[]
[]
[]
0
[ "2lsm" ]
1
[ "PUB00057300" ]
[ "8468297" ]
[ "Sites and gene products involved in lambdoid phage DNA packaging." ]
[ 1993 ]
1
[]
[]
0
0
null
[ "Bacteria", "Caudoviricetes", "Methanobrevibacter smithii DSM 2375", "human gut metagenome" ]
[ 745, 19, 1, 2 ]
4
[]
[]
0
true
Family
DNA packaging protein FI
DNA packaging protein FI
Packaging_FI
1
IPR025149
25,149
Protein of unknown function DUF4090
DUF4090
Family
305
false
false
This family of proteins is found in cyanobacteria and is functionally uncharacterised. Proteins in this family are approximately 90 amino acids in length. A member of this family, the ssr1528 gene was found to be regulated by an sRNA NsiR4 [ ]. In addition, the expression of that gene was repressed under conditions of ...
[]
[]
[]
0
[ "NCBIFAM", "PFAM" ]
[ "NF050008", "PF13319" ]
[ "ssr1528_fam", "DUF4090" ]
[ 298, 305 ]
2
[]
[]
[]
0
[]
0
[ "PUB00088099" ]
[ "26494284" ]
[ "The sRNA NsiR4 is involved in nitrogen assimilation control in cyanobacteria by targeting glutamine synthetase inactivating factor IF7." ]
[ 2015 ]
1
[]
[]
0
0
null
[ "Cyanophyceae", "marine metagenome" ]
[ 304, 1 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF4090
Protein of unknown function DUF4090
DUF4090
8