interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR025025 | 25,025 | Protein of unknown function DUF3914 | DUF3914 | Family | 179 | false | false | This family of proteins is functionally uncharacterised. There are two conserved sequence motifs: KFDIR and DLW. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13053"
] | [
"DUF3914"
] | [
179
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
179
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3914 | Protein of unknown function DUF3914 | DUF3914 | 4 |
IPR025026 | 25,026 | Protein of unknown function DUF3915 | DUF3915 | Family | 193 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13054"
] | [
"DUF3915"
] | [
193
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
176,
17
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF3915 | Protein of unknown function DUF3915 | DUF3915 | 2 |
IPR025027 | 25,027 | Protein of unknown function DUF3917 | DUF3917 | Family | 133 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13055"
] | [
"DUF3917"
] | [
133
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
133
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3917 | Protein of unknown function DUF3917 | DUF3917 | 1 |
IPR025029 | 25,029 | Protein of unknown function DUF3918 | DUF3918 | Family | 364 | false | false | This family of proteins is functionally uncharacterised. There are two completely conserved residues (G and R) that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13056"
] | [
"DUF3918"
] | [
364
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales",
"Peronospora effusa"
] | [
363,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF3918 | Protein of unknown function DUF3918 | DUF3918 | 6 |
IPR025030 | 25,030 | Domain of unknown function DUF3950 | DUF3950 | Domain | 754 | false | false | This presumed domain is functionally uncharacterised. It is approximately 30 amino acids in length and contains a conserved NFS sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13132"
] | [
"DUF3950"
] | [
754
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota"
] | [
735,
17,
2
] | 3 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Domain | Domain of unknown function DUF3950 | Domain of unknown function DUF3950 | DUF3950 | 9 |
IPR025031 | 25,031 | Protein of unknown function DUF3919 | DUF3919 | Family | 336 | false | false | This family of proteins is functionally uncharacterised. There is a conserved YLNG sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13057"
] | [
"DUF3919"
] | [
336
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Strongyloides venezuelensis"
] | [
335,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF3919 | Protein of unknown function DUF3919 | DUF3919 | 4 |
IPR025032 | 25,032 | Protein of unknown function DUF3949 | DUF3949 | Family | 402 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13133"
] | [
"DUF3949"
] | [
402
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
402
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3949 | Protein of unknown function DUF3949 | DUF3949 | 8 |
IPR025033 | 25,033 | Protein of unknown function DUF3920 | DUF3920 | Family | 210 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13058"
] | [
"DUF3920"
] | [
210
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae"
] | [
210
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3920 | Protein of unknown function DUF3920 | DUF3920 | 5 |
IPR025034 | 25,034 | Protein of unknown function DUF3948 | DUF3948 | Family | 639 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13134"
] | [
"DUF3948"
] | [
639
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
639
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3948 | Protein of unknown function DUF3948 | DUF3948 | 7 |
IPR025035 | 25,035 | Protein of unknown function DUF3922 | DUF3922 | Family | 177 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13059"
] | [
"DUF3922"
] | [
177
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
177
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3922 | Protein of unknown function DUF3922 | DUF3922 | 3 |
IPR025036 | 25,036 | Protein of unknown function DUF3921 | DUF3921 | Family | 145 | false | false | This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. External database links | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13060"
] | [
"DUF3921"
] | [
145
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae"
] | [
145
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3921 | Protein of unknown function DUF3921 | DUF3921 | 9 |
IPR025037 | 25,037 | Protein of unknown function DUF3923 | DUF3923 | Family | 559 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13061"
] | [
"DUF3923"
] | [
559
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
559
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3923 | Protein of unknown function DUF3923 | DUF3923 | 7 |
IPR025038 | 25,038 | Protein of unknown function DUF3924 | DUF3924 | Family | 124 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13062"
] | [
"DUF3924"
] | [
124
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
124
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3924 | Protein of unknown function DUF3924 | DUF3924 | 5 |
IPR025040 | 25,040 | Protein of unknown function DUF3984 | DUF3984 | Family | 1,029 | false | false | This family of proteins is currently functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13136"
] | [
"DUF3984"
] | [
1029
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1029
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF3984 | Protein of unknown function DUF3984 | DUF3984 | 9 |
IPR025041 | 25,041 | Protein of unknown function DUF3983 | DUF3983 | Family | 205 | false | false | This family of proteins is functionally uncharacterised. Proteins in this family contain a conserved AWRN sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13137"
] | [
"DUF3983"
] | [
205
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae",
"Caudoviricetes"
] | [
190,
15
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF3983 | Protein of unknown function DUF3983 | DUF3983 | 3 |
IPR025043 | 25,043 | Domain of unknown function DUF3981 | DUF3981 | Domain | 192 | false | false | This presumed domain, approximately 110 amino acids in length, is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13139"
] | [
"DUF3981"
] | [
192
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
192
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF3981 | Domain of unknown function DUF3981 | DUF3981 | 7 |
IPR025044 | 25,044 | Domain of unknown function DUF3980 | DUF3980 | Domain | 177 | false | false | This presumed domain, approximately 90 amino acids in length, is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13140"
] | [
"DUF3980"
] | [
177
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae"
] | [
177
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF3980 | Domain of unknown function DUF3980 | DUF3980 | 2 |
IPR025045 | 25,045 | Protein of unknown function DUF3979 | DUF3979 | Family | 169 | false | false | This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria. Proteins in this family are approximately 120 amino acids in length. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13141"
] | [
"DUF3979"
] | [
169
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae"
] | [
169
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3979 | Protein of unknown function DUF3979 | DUF3979 | 7 |
IPR025046 | 25,046 | Domain of unknown function DUF3960 | DUF3960 | Domain | 173 | false | false | This presumed domain, typically between 72 and 89 amino acids in length, is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13142"
] | [
"DUF3960"
] | [
173
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae"
] | [
173
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF3960 | Domain of unknown function DUF3960 | DUF3960 | 5 |
IPR025047 | 25,047 | Protein of unknown function DUF3986 | DUF3986 | Family | 464 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13143"
] | [
"DUF3986"
] | [
464
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota",
"Funneliformis caledonium"
] | [
461,
3
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF3986 | Protein of unknown function DUF3986 | DUF3986 | 6 |
IPR025049 | 25,049 | Fimbrillin-like 1 | Mfa-like_1 | Family | 5,971 | false | false | A family of putative fimbrillin proteins found by clustering human gut metagenomic sequences [ ]. Analysis of structural comparisons shows this family to be part of the FimbA (CL0450) superfamily of adhesin components or fimbrillins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13149"
] | [
"Mfa_like_1"
] | [
5971
] | 1 | [] | [] | [] | 0 | [
"3sy6",
"3t2l",
"3ufi",
"4dgu",
"4eps",
"4k4k",
"4qb7"
] | 7 | [
"PUB00055601"
] | [
"20532204"
] | [
"Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families."
] | [
2010
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Streblomastix strix",
"metagenomes"
] | [
5870,
2,
99
] | 3 | [] | [] | 0 | true | Family | Fimbrillin-like 1 | Fimbrillin-like 1 | Mfa-like_1 | 6 |
IPR025051 | 25,051 | Protein of unknown function DUF3990 | DUF3990 | Family | 2,155 | false | false | This entry represents a family of uncharacterised proteins that was originally found by clustering human gut metagenomic sequences [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13151"
] | [
"DUF3990"
] | [
2155
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00055601"
] | [
"20532204"
] | [
"Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families."
] | [
2010
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriati",
"unclassified Caudoviricetes",
"unclassified sequences"
] | [
2006,
99,
6,
5,
39
] | 5 | [] | [] | 0 | true | Family | Protein of unknown function DUF3990 | Protein of unknown function DUF3990 | DUF3990 | 7 |
IPR025052 | 25,052 | Domain of unknown function DUF3967 | DUF3967 | Domain | 796 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13152"
] | [
"DUF3967"
] | [
796
] | 1 | [] | [] | [] | 0 | [
"7c7y"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus phage Deep-Purple",
"Bacteria",
"Rhizophagus irregularis (strain DAOM 197198w)"
] | [
1,
794,
1
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF3967 | Domain of unknown function DUF3967 | DUF3967 | 8 |
IPR025053 | 25,053 | Protein of unknown function DUF3985 | DUF3985 | Family | 110 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13153"
] | [
"DUF3985"
] | [
110
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
110
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3985 | Protein of unknown function DUF3985 | DUF3985 | 3 |
IPR025054 | 25,054 | Domain of unknown function DUF3991 | DUF3991 | Domain | 3,004 | false | false | The function is this domain is not known. It is often associated with a Toprim (topoisomerase-primase) domain ( ). | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13154"
] | [
"DUF3991"
] | [
3004
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Chiloscyllium punctatum",
"unclassified sequences"
] | [
2964,
1,
39
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF3991 | Domain of unknown function DUF3991 | DUF3991 | 2 |
IPR025055 | 25,055 | Endospore appendages core | Ena_core | Domain | 934 | false | false | The surface of Bacillus and Clostridium endospores is decorated with long filamentous endospores appendages that resemble pili from Gram-negative and Gram-positive bacteria. They show two morphologies, the main or Staggered-type (S-Ena) which accounts for 90% of the fibres, and the Ladder-like (L-Ena) which is smaller ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13157"
] | [
"Enas"
] | [
934
] | 1 | [] | [] | [] | 0 | [
"7a02",
"8pdz",
"9i0y"
] | 3 | [
"PUB00098173"
] | [
"34031903"
] | [
"Endospore Appendages: a novel pilus superfamily from the endospores of pathogenic Bacilli."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
933,
1
] | 2 | [] | [] | 0 | true | Domain | Endospore appendages core | Endospore appendages core | Ena_core | 8 |
IPR025056 | 25,056 | Protein of unknown function DUF3993 | DUF3993 | Family | 339 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13158"
] | [
"DUF3993"
] | [
339
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
339
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3993 | Protein of unknown function DUF3993 | DUF3993 | 9 |
IPR025057 | 25,057 | Domain of unknown function DUF3994 | DUF3994 | Domain | 305 | false | false | This domain is found at the C-terminal of a group of proteins from Bacillus that have at the N-terminal. Members are functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13159"
] | [
"DUF3994"
] | [
305
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
305
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF3994 | Domain of unknown function DUF3994 | DUF3994 | 7 |
IPR025058 | 25,058 | Protein of unknown function DUF3995 | DUF3995 | Family | 2,396 | false | false | This family of proteins is functionally uncharacterised. Proteins in this family are typically between 138 and 149 amino acids in length and contain two completely conserved residues (W and P) that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13160"
] | [
"DUF3995"
] | [
2396
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halobacteriales",
"Ricinus communis",
"metagenomes"
] | [
2368,
13,
1,
14
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF3995 | Protein of unknown function DUF3995 | DUF3995 | 9 |
IPR025059 | 25,059 | Protein of unknown function DUF3997 | DUF3997 | Family | 292 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13162"
] | [
"DUF3997"
] | [
292
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"unclassified sequences"
] | [
288,
2,
2
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF3997 | Protein of unknown function DUF3997 | DUF3997 | 3 |
IPR025060 | 25,060 | Protein of unknown function DUF3999 | DUF3999 | Family | 1,920 | false | false | This family of proteins is functionally uncharacterised. Proteins in this family are typically between 440 and 470 amino acids in length and contain a single completely conserved residue D that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13163"
] | [
"DUF3999"
] | [
1920
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1908,
4,
8
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF3999 | Protein of unknown function DUF3999 | DUF3999 | 6 |
IPR025061 | 25,061 | Diedel | Diedel | Family | 193 | false | false | Diedel (die) was identified as an insect immune response protein. It is up-regulated after a septic injury and may act as a negative regulator of the JAK/STAT signalling pathway [ ]. Its homologues can be found in Drosophila and Acyrtosiphon pisum. Interestingly, the orthologues of the die gene are present in the genom... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13164"
] | [
"Diedel"
] | [
193
] | 1 | [] | [] | [] | 0 | [
"3zzo",
"3zzr"
] | 2 | [
"PUB00078735",
"PUB00078736"
] | [
"22442689",
"26739560"
] | [
"Crystal structure of Diedel, a marker of the immune response of Drosophila melanogaster.",
"Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila."
] | [
2012,
2016
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Viruses"
] | [
175,
18
] | 2 | [
"Drosophila melanogaster"
] | [
9
] | 1 | true | Family | Diedel | Diedel | Diedel | 3 |
IPR025062 | 25,062 | Protein of unknown function DUF4003 | DUF4003 | Family | 1,030 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13170"
] | [
"DUF4003"
] | [
1030
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
1025,
5
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4003 | Protein of unknown function DUF4003 | DUF4003 | 6 |
IPR025063 | 25,063 | Protein of unknown function DUF4004 | DUF4004 | Family | 828 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13171"
] | [
"DUF4004"
] | [
828
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanobacterium",
"Phytophthora kernoviae 00238/432",
"unclassified sequences"
] | [
818,
6,
1,
3
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF4004 | Protein of unknown function DUF4004 | DUF4004 | 6 |
IPR025064 | 25,064 | Domain of unknown function DUF4005 | DUF4005 | Domain | 11,487 | false | false | This domain is found towards the C terminus of a number of plant IQ domain-containing proteins. These proteins may be involved in cooperative interactions with calmodulins or calmodulin-like proteins, and may associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13178"
] | [
"DUF4005"
] | [
11487
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta",
"Limnospira"
] | [
11485,
2
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
100,
39,
77
] | 3 | true | Domain | Domain of unknown function DUF4005 | Domain of unknown function DUF4005 | DUF4005 | 6 |
IPR025066 | 25,066 | Coiled-coil domain-containing protein 174-like | CCDC174-like | Family | 3,874 | false | false | This entry represents CCDC174 and related proteins from animals, fungi and plants. CCDC174 is a ubiquitous protein which is restricted to the cell nucleus and co-localises with EIF4A3 [ ]. Mutations in this gene have been linked to a syndrome characterised by hypotonia (low muscle tone) and psychomotor developmental de... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR15885"
] | [
""
] | [
3874
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00098151"
] | [
"26358778"
] | [
"CDC174, a novel component of the exon junction complex whose mutation underlies a syndrome of hypotonia and psychomotor developmental delay."
] | [
2015
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3874
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Schizosaccharomyces pombe (stra... | [
2,
1,
2,
1,
3,
5,
1,
2,
4,
1,
7
] | 11 | true | Family | Coiled-coil domain-containing protein 174-like | Coiled-coil domain-containing protein 174-like | CCDC174-like | 5 |
IPR025067 | 25,067 | Protein of unknown function DUF4079 | DUF4079 | Family | 2,544 | false | false | This is an uncharacterised family of proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13301"
] | [
"DUF4079"
] | [
2544
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"marine sediment metagenome"
] | [
2,
1222,
1319,
1
] | 4 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
7,
7,
7
] | 3 | true | Family | Protein of unknown function DUF4079 | Protein of unknown function DUF4079 | DUF4079 | 4 |
IPR025068 | 25,068 | Protein of unknown function DUF3937 | DUF3937 | Family | 143 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13073"
] | [
"DUF3937"
] | [
143
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
143
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3937 | Protein of unknown function DUF3937 | DUF3937 | 8 |
IPR025069 | 25,069 | Cleavage and polyadenylation specificity factor 2, C-terminal | Cpsf2_C | Domain | 4,329 | false | false | This domain lies at the C terminus of many fungal and plant cleavage and polyadenylation specificity factor subunit 2 proteins. The exact function of the domain is not known, but is likely to function as a binding domain for the protein within the overall CPSF complex [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13299"
] | [
"CPSF100_C"
] | [
4329
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-159231",
"R-BTA-72187",
"R-BTA-72203",
"R-BTA-73856",
"R-BTA-77595",
"R-CEL-72187",
"R-CEL-72203",
"R-CEL-73856",
"R-CEL-77595",
"R-DDI-77595",
"R-DME-159231",
"R-DME-72187",
"R-DME-72203",
"R-DME-73856",
"R-DME-77595",
"R-HSA-159231",
"R-HSA-72187",
"R-HSA-72203",
"R-HSA-... | [
"REACTOME:R-BTA-159231",
"REACTOME:R-BTA-72187",
"REACTOME:R-BTA-72203",
"REACTOME:R-BTA-73856",
"REACTOME:R-BTA-77595",
"REACTOME:R-CEL-72187",
"REACTOME:R-CEL-72203",
"REACTOME:R-CEL-73856",
"REACTOME:R-CEL-77595",
"REACTOME:R-DDI-77595",
"REACTOME:R-DME-159231",
"REACTOME:R-DME-72187",
"R... | 28 | [
"6urg",
"6v4x",
"8ba1"
] | 3 | [
"PUB00057294"
] | [
"19748916"
] | [
"Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies."
] | [
2009
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4329
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
4,
1,
3,
1,
4,
1,
1,
1,
4,
1,
1,
6
] | 12 | true | Domain | Cleavage and polyadenylation specificity factor 2, C-terminal | Cleavage and polyadenylation specificity factor 2, C-terminal | Cpsf2_C | 6 |
IPR025071 | 25,071 | Protein of unknown function DUF3939 | DUF3939 | Family | 401 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13075"
] | [
"DUF3939"
] | [
401
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
401
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3939 | Protein of unknown function DUF3939 | DUF3939 | 3 |
IPR025072 | 25,072 | Fur-regulated basic protein A | Fur_reg_FbpA | Domain | 1,143 | false | false | This entry represents Uncharacterized protein YebD which is regulated by the ferric uptake regulator protein Fur [ ]. This protein does not regulate the lutABC operon encoding iron-sulphur-containing enzymes necessary for growth on lactate [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13076"
] | [
"Fur_reg_FbpA"
] | [
1143
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00075677",
"PUB00075678"
] | [
"18697947",
"22427629"
] | [
"The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.",
"The FsrA sRNA and FbpB protein mediate the iron-dependent induction of the Bacillus subtilis lutABC iron-sulfur-containing oxidases."
] | [
2008,
2012
] | 2 | [] | [] | 0 | 0 | null | [
"Bacillota",
"Caudoviricetes"
] | [
1135,
8
] | 2 | [] | [] | 0 | true | Domain | Fur-regulated basic protein A | Fur-regulated basic protein A | Fur_reg_FbpA | 6 |
IPR025074 | 25,074 | Protein of unknown function DUF3942 | DUF3942 | Family | 167 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13078"
] | [
"DUF3942"
] | [
167
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
167
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3942 | Protein of unknown function DUF3942 | DUF3942 | 2 |
IPR025075 | 25,075 | Protein of unknown function DUF3916 | DUF3916 | Family | 504 | false | false | This family of proteins is functionally uncharacterised. There is a single completely conserved residue S that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13079"
] | [
"DUF3916"
] | [
504
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
503,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF3916 | Protein of unknown function DUF3916 | DUF3916 | 7 |
IPR025079 | 25,079 | Domain of unknown function DUF3943 | DUF3943 | Domain | 1,083 | false | false | This presumed domain is functionally uncharacterised. It is approximately 110 amino acids in length. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13084"
] | [
"DUF3943"
] | [
1083
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Russula earlei",
"metagenomes"
] | [
1063,
1,
19
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF3943 | Domain of unknown function DUF3943 | DUF3943 | 6 |
IPR025080 | 25,080 | Protein of unknown function DUF3959 | DUF3959 | Family | 201 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13105"
] | [
"DUF3959"
] | [
201
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae"
] | [
201
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3959 | Protein of unknown function DUF3959 | DUF3959 | 3 |
IPR025081 | 25,081 | Domain of unknown function DUF3961 | DUF3961 | Domain | 180 | false | false | This presumed domain is functionally uncharacterised. It is approximately 40 amino acids in length. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13106"
] | [
"DUF3961"
] | [
180
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae",
"Wbetavirus"
] | [
173,
7
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF3961 | Domain of unknown function DUF3961 | DUF3961 | 4 |
IPR025082 | 25,082 | Protein of unknown function DUF3964 | DUF3964 | Family | 193 | false | false | This family of proteins is functionally uncharacterised. There are two conserved sequence motifs: FYF and AFW. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13107"
] | [
"DUF3964"
] | [
193
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
193
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF3964 | Protein of unknown function DUF3964 | DUF3964 | 8 |
IPR025083 | 25,083 | Protein of unknown function DUF3969 | DUF3969 | Family | 400 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13108"
] | [
"DUF3969"
] | [
400
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Staphylococcus phage phiSP44-1"
] | [
399,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF3969 | Protein of unknown function DUF3969 | DUF3969 | 1 |
IPR025085 | 25,085 | pPIWI_RE module, N-terminal domain | pPIWI_RE_X | Domain | 829 | false | false | This entry represents a domain N-terminal to the pPIWI_RE domain module. PIWI/Argonaute modules are typically N-terminally fused to the PTND1 and PTND2 domains [ ], pPIWI_RE_X may represent an ancestral version of these domains or represent a N-terminal innovation predating the emergence of PTND1 and PTND2 [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13111"
] | [
"pPIWI_RE_X"
] | [
829
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00091015",
"PUB00091016"
] | [
"24311560",
"23758928"
] | [
"New perspectives on the diversification of the RNA interference system: insights from comparative genomics and small RNA sequencing.",
"Two novel PIWI families: roles in inter-genomic conflicts in bacteria and Mediator-dependent modulation of transcription in eukaryotes."
] | [
2014,
2013
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
828,
1
] | 2 | [] | [] | 0 | true | Domain | pPIWI_RE module, N-terminal domain | pPIWI_RE module, N-terminal domain | pPIWI_RE_X | 7 |
IPR025086 | 25,086 | SDE2/SF3A3, SAP domain | SDE2/SF3A3_SAP | Domain | 4,524 | false | false | This is the SAP domain found at the C-terminal of SDE2 and in the middle region of splicing factor 3A subunit 3 (SF3A, also known as noisette) [ , , , ]. SDE2 is both an RNA-binding protein and also a trans-acting adaptor protein that functions to regulate RNA splicing and ribosome biogenesis. SF3A is involved in pre-m... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13297"
] | [
"SDE2_2C"
] | [
4524
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DRE-72163",
"R-HSA-72163",
"R-MMU-72163",
"R-RNO-72163"
] | [
"REACTOME:R-DRE-72163",
"REACTOME:R-HSA-72163",
"REACTOME:R-MMU-72163",
"REACTOME:R-RNO-72163"
] | 4 | [
"5z56",
"5z57",
"5z58",
"6ah0",
"6ahd",
"6ff7",
"6qx9",
"6y50",
"6y53",
"6y5q",
"7abg",
"7abh",
"7abi",
"7evo",
"7n99",
"7onb",
"7q3l",
"7q4o",
"7q4p",
"7qtt",
"7vpx",
"8c6j",
"8ch6",
"8h6e",
"8h6j",
"8h6k",
"8h6l",
"8hk1",
"8i0p",
"8i0r",
"8i0s",
"8i0t"... | 44 | [
"PUB00057296",
"PUB00094506",
"PUB00101924",
"PUB00101933",
"PUB00101934",
"PUB00154351"
] | [
"9528755",
"29360106",
"30315277",
"34365507",
"27906959",
"35850305"
] | [
"Multiple developmental requirements of noisette, the Drosophila homolog of the U2 snRNP-associated polypeptide SP3a60.",
"Structure of the human activated spliceosome in three conformational states.",
"Structures of the human pre-catalytic spliceosome and its precursor spliceosome.",
"SDE2 is an essential ge... | [
1998,
2018,
2018,
2021,
2016,
2022
] | 6 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4524
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
14,
2,
3,
1,
7,
3,
6,
7,
19
] | 9 | true | Domain | SDE2/SF3A3, SAP domain | SDE2/SF3A3, SAP domain | SDE2/SF3A3_SAP | 3 |
IPR025088 | 25,088 | Protein of unknown function DUF3970 | DUF3970 | Family | 261 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13113"
] | [
"DUF3970"
] | [
261
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"human gut metagenome"
] | [
260,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF3970 | Protein of unknown function DUF3970 | DUF3970 | 4 |
IPR025089 | 25,089 | Protein of unknown function DUF4018 | DUF4018 | Family | 217 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13210"
] | [
"DUF4018"
] | [
217
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillaceae"
] | [
217
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4018 | Protein of unknown function DUF4018 | DUF4018 | 9 |
IPR025090 | 25,090 | Protein of unknown function DUF4017 | DUF4017 | Family | 192 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13209"
] | [
"DUF4017"
] | [
192
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
192
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4017 | Protein of unknown function DUF4017 | DUF4017 | 2 |
IPR025091 | 25,091 | Protein of unknown function DUF4019 | DUF4019 | Family | 1,274 | false | false | This family of proteins is functionally uncharacterised. There is a single completely conserved residue E that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13211"
] | [
"DUF4019"
] | [
1274
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"ecological metagenomes"
] | [
1266,
2,
6
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4019 | Protein of unknown function DUF4019 | DUF4019 | 6 |
IPR025092 | 25,092 | Glycosyl hydrolase family 66 | Glyco_hydro_66 | Family | 827 | false | false | This family is a set of glycosyl hydrolase enzymes including cycloisomaltooligosaccharide glucanotransferase ([ec:2.4.1.-]) and dextranase ( ) activities. | [] | [] | [] | 0 | [
"PFAM",
"CDD"
] | [
"PF13199",
"cd14745"
] | [
"Glyco_hydro_66",
"GH66"
] | [
827,
657
] | 2 | [
"EC"
] | [
"3.2.1.11"
] | [
"EC:3.2.1.11"
] | 1 | [
"3vmn",
"3vmo",
"3vmp",
"3wnk",
"3wnl",
"3wnm",
"3wnn",
"3wno",
"3wnp",
"5axg",
"5axh",
"5x7g",
"5x7h",
"8iu8",
"8iu9",
"8iua",
"8iub"
] | 17 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Dinophyceae",
"metagenomes"
] | [
806,
7,
14
] | 3 | [] | [] | 0 | true | Family | Glycosyl hydrolase family 66 | Glycosyl hydrolase family 66 | Glyco_hydro_66 | 8 |
IPR025094 | 25,094 | Protein of unknown function DUF4021 | DUF4021 | Family | 212 | false | false | This family of proteins is functionally uncharacterised. There is a conserved YGM sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13213"
] | [
"DUF4021"
] | [
212
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
212
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4021 | Protein of unknown function DUF4021 | DUF4021 | 8 |
IPR025095 | 25,095 | Protein of unknown function DUF4022 | DUF4022 | Family | 175 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13214"
] | [
"DUF4022"
] | [
175
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
175
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4022 | Protein of unknown function DUF4022 | DUF4022 | 2 |
IPR025096 | 25,096 | Protein of unknown function DUF4014 | DUF4014 | Family | 227 | false | false | This is a bacterial and viral family of uncharacterised proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13198"
] | [
"DUF4014"
] | [
227
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Caudoviricetes",
"Enterobacteriaceae"
] | [
40,
187
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4014 | Protein of unknown function DUF4014 | DUF4014 | 6 |
IPR025097 | 25,097 | Protein of unknown function DUF4023 | DUF4023 | Family | 562 | false | false | This family of proteins is functionally uncharacterised. There is a conserved KLP sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13215"
] | [
"DUF4023"
] | [
562
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota",
"bioreactor metagenome"
] | [
561,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4023 | Protein of unknown function DUF4023 | DUF4023 | 1 |
IPR025099 | 25,099 | Protein of unknown function DUF4024 | DUF4024 | Family | 73 | false | false | This family of proteins is functionally uncharacterised. There is a conserved RDE sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13216"
] | [
"DUF4024"
] | [
73
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
73
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4024 | Protein of unknown function DUF4024 | DUF4024 | 9 |
IPR025100 | 25,100 | Protein of unknown function DUF4025 | DUF4025 | Family | 652 | false | false | This family of proteins is functionally uncharacterised. There is a conserved EGT sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13217"
] | [
"DUF4025"
] | [
652
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
652
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4025 | Protein of unknown function DUF4025 | DUF4025 | 8 |
IPR025101 | 25,101 | Protein of unknown function DUF4012 | DUF4012 | Family | 3,450 | false | false | This is a family of uncharacterised proteins found in archaea and bacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13196"
] | [
"DUF4012"
] | [
3450
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Acrobeloides nanus",
"Bacteria",
"Methanobacteriaceae",
"unclassified sequences"
] | [
1,
3307,
74,
68
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF4012 | Protein of unknown function DUF4012 | DUF4012 | 9 |
IPR025102 | 25,102 | DUF4026, N-terminal | DUF4026_N | Domain | 377 | false | false | This entry represents a domain is found N-terminal in functionally uncharacterised bacterial proteins. This domain is found in association with and , that are located C-terminal. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13218"
] | [
"DUF4026_N"
] | [
377
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
377
] | 1 | [] | [] | 0 | true | Domain | DUF4026, N-terminal | DUF4026, N-terminal | DUF4026_N | 5 |
IPR025103 | 25,103 | Uncharacterized ATP-dependent helicase MG140, N-terminal domain | DUF4011 | Domain | 4,217 | false | false | This domain is found at the N-terminal of Uncharacterized ATP-dependent helicase MG140 and its homologues from archaea and bacteria. Many members are annotated as being putative DNA helicase-related proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13195"
] | [
"DUF4011"
] | [
4217
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
142,
4032,
7,
36
] | 4 | [] | [] | 0 | true | Domain | Uncharacterized ATP-dependent helicase MG140, N-terminal domain | Uncharacterized ATP-dependent helicase MG140, N-terminal domain | DUF4011 | 2 |
IPR025105 | 25,105 | Domain of unknown function DUF4010 | DUF4010 | Domain | 3,899 | false | false | This domain is found in putative membrane proteins from archaea and bacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13194"
] | [
"DUF4010"
] | [
3899
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Ricinus communis",
"unclassified sequences"
] | [
520,
3307,
1,
71
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4010 | Domain of unknown function DUF4010 | DUF4010 | 2 |
IPR025106 | 25,106 | Protein of unknown function DUF4028 | DUF4028 | Family | 150 | false | false | This family of proteins is functionally uncharacterised. There are two conserved sequence motifs: IVKI and YVKKWF. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13220"
] | [
"DUF4028"
] | [
150
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
150
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4028 | Protein of unknown function DUF4028 | DUF4028 | 4 |
IPR025107 | 25,107 | Protein of unknown function DUF4029 | DUF4029 | Family | 160 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13221"
] | [
"DUF4029"
] | [
160
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
160
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4029 | Protein of unknown function DUF4029 | DUF4029 | 4 |
IPR025108 | 25,108 | Protein of unknown function DUF4030 | DUF4030 | Family | 180 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13222"
] | [
"DUF4030"
] | [
180
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
180
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4030 | Protein of unknown function DUF4030 | DUF4030 | 7 |
IPR025109 | 25,109 | Domain of unknown function DUF4031 | DUF4031 | Domain | 3,477 | false | false | This presumed domain is functionally uncharacterised. It contains a conserved HYD sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13223"
] | [
"DUF4031"
] | [
3477
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
3330,
6,
60,
81
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4031 | Domain of unknown function DUF4031 | DUF4031 | 7 |
IPR025110 | 25,110 | AMP-binding enzyme, C-terminal domain | AMP-bd_C | Domain | 382,527 | false | false | This is a small domain that is found C-terminal to in ATP-dependent AMP-binding enzymes from eukaryotes, bacteria and archaea, including Acetyl-coenzyme A synthetase (Acs). In Acs, this domain undergoes a large rotation to allow for both half-reaction to occur. It shows a central β-sheet core that is flanked by α-helic... | [] | [] | [] | 0 | [
"PFAM",
"PFAM"
] | [
"PF13193",
"PF23024"
] | [
"AMP-binding_C",
"AMP-dom_DIP2-like"
] | [
367813,
15353
] | 2 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"6.2.1",
"GenProp1308",
"GenProp1452",
"GenProp1462",
"GenProp1562",
"GenProp1572",
"GenProp1717",
"R-BTA-75876",
"R-BTA-77111",
"R-BTA-77289",
"R-CEL-77111",
"R-DDI-2151201",
"R-DDI-71384",
"R-DDI-77111",
"R-DME-71384",
"R-DRE-77289",
"R-HSA-159418",
"R-HSA-177128",
"R-HSA-17713... | [
"EC:6.2.1",
"GP:GenProp1308",
"GP:GenProp1452",
"GP:GenProp1462",
"GP:GenProp1562",
"GP:GenProp1572",
"GP:GenProp1717",
"REACTOME:R-BTA-75876",
"REACTOME:R-BTA-77111",
"REACTOME:R-BTA-77289",
"REACTOME:R-CEL-77111",
"REACTOME:R-DDI-2151201",
"REACTOME:R-DDI-71384",
"REACTOME:R-DDI-77111",
... | 77 | [
"1amu",
"1ba3",
"1lci",
"1md9",
"1mdb",
"1mdf",
"1pg3",
"1pg4",
"1ry2",
"1t5d",
"1t5h",
"1ult",
"1v25",
"1v26",
"2d1q",
"2d1r",
"2d1s",
"2d1t",
"2p20",
"2p2b",
"2p2f",
"2p2j",
"2p2m",
"2p2q",
"2qvx",
"2qvy",
"2qvz",
"2qw0",
"2v7b",
"2vsq",
"2vze",
"2wd9"... | 301 | [
"PUB00028100",
"PUB00097529"
] | [
"12627952",
"27908785"
] | [
"The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A.",
"DISCO Interacting Protein 2 regulates axonal bifurcation and guidance of Drosophila mushroom body neurons."
] | [
2003,
2017
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Sym plasmid",
"Viruses",
"unclassified sequences"
] | [
5704,
283000,
90081,
1,
3,
3738
] | 6 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
160,
32,
77,
38,
7,
67,
64,
16,
82,
82,
4,
5,
120
] | 13 | true | Domain | AMP-binding enzyme, C-terminal domain | AMP-binding enzyme, C-terminal domain | AMP-bd_C | 1 |
IPR025111 | 25,111 | Domain of unknown function DUF4032 | DUF4032 | Domain | 3,096 | false | false | This presumed domain is functionally uncharacterised. It is found in bacteria, and is approximately 170 amino acids in length. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13224"
] | [
"DUF4032"
] | [
3096
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
2983,
113
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4032 | Domain of unknown function DUF4032 | DUF4032 | 2 |
IPR025112 | 25,112 | Putative carbohydrate metabolism domain | PCMD | Domain | 1,833 | false | false | This domain has been suggested to participate in carbohydrate metabolism [ ]. Structural evidence indicates that it might be a carbohydrate binding domain, with or without enzymatic activity. In particular, it has been hypothesised that it might act as a glycoside hydrolase [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13201"
] | [
"PCMD"
] | [
1833
] | 1 | [] | [] | [] | 0 | [
"3hbz",
"3s30",
"4het",
"4jrl"
] | 4 | [
"PUB00061399"
] | [
"20944224"
] | [
"Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 A resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism."
] | [
2010
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
1814,
19
] | 2 | [] | [] | 0 | true | Domain | Putative carbohydrate metabolism domain | Putative carbohydrate metabolism domain | PCMD | 3 |
IPR025113 | 25,113 | TRL-like protein family | TRL-like | Family | 1,302 | false | false | This family includes the TRL protein that is found in a locus that includes several tRNAs. The function of this protein is not known [ ]. The proteins in this family usually have a lipoprotein attachment site at their N terminus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13146"
] | [
"TRL"
] | [
1302
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00057297"
] | [
"10411255"
] | [
"A novel tRNA-associated locus (trl) from Helicobacter pylori is co-transcribed with tRNA(Gly) and reveals genetic diversity."
] | [
1999
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
1299,
3
] | 2 | [] | [] | 0 | true | Family | TRL-like protein family | TRL-like protein family | TRL-like | 5 |
IPR025114 | 25,114 | Beta-carotene isomerase D27-like, C-terminal | D27-like_C | Domain | 2,194 | false | false | Beta-carotene isomerase D27 (also known as Protein DWARF-27) from plants is involved in strigolactones biosynthesis. It is a beta-carotene isomerase that converts all-trans-beta-carotene into 9-cis-beta-carotene, which is cleaved by CCD7 into a 9-cis-configured aldehyde [ , ]. This is an iron-containing protein that lo... | [
"GO:0005506"
] | [
"iron ion binding"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF13225"
] | [
"D27-like_C"
] | [
2194
] | 1 | [
"EC",
"METACYC"
] | [
"5.2.1.14",
"PWY-7101"
] | [
"EC:5.2.1.14",
"METACYC:PWY-7101"
] | 2 | [] | 0 | [
"PUB00088582",
"PUB00095645",
"PUB00095646"
] | [
"22422982",
"22623516",
"19470589"
] | [
"The path from β-carotene to carlactone, a strigolactone-like plant hormone.",
"The Arabidopsis ortholog of rice DWARF27 acts upstream of MAX1 in the control of plant development by strigolactones.",
"DWARF27, an iron-containing protein required for the biosynthesis of strigolactones, regulates rice tiller bud ... | [
2012,
2012,
2009
] | 3 | [] | [] | 0 | 0 | null | [
"Bacillati",
"Eukaryota"
] | [
49,
2145
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
14,
9,
34
] | 3 | true | Domain | Beta-carotene isomerase D27-like, C-terminal | Beta-carotene isomerase D27-like, C-terminal | D27-like_C | 5 |
IPR025115 | 25,115 | Domain of unknown function DUF4034 | DUF4034 | Domain | 1,224 | false | false | This presumed domain is functionally uncharacterised. It contains a conserved PRW sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13226"
] | [
"DUF4034"
] | [
1224
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Knufia peltigerae",
"hydrothermal vent metagenome"
] | [
1222,
1,
1
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4034 | Domain of unknown function DUF4034 | DUF4034 | 9 |
IPR025117 | 25,117 | Domain of unknown function DUF4037 | DUF4037 | Domain | 2,600 | false | false | This presumed domain is functionally uncharacterised. There is a single completely conserved residue P that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13228"
] | [
"DUF4037"
] | [
2600
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
5,
2542,
31,
22
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4037 | Domain of unknown function DUF4037 | DUF4037 | 8 |
IPR025120 | 25,120 | Domain of unknown function DUF4047 | DUF4047 | Domain | 208 | false | false | This presumed domain is functionally uncharacterised. There are two conserved sequence motifs: TEA and FPKT. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13256"
] | [
"DUF4047"
] | [
208
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Tritrichomonas musculus"
] | [
207,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4047 | Domain of unknown function DUF4047 | DUF4047 | 9 |
IPR025121 | 25,121 | GTPase HflX, N-terminal | GTPase_HflX_N | Domain | 28,593 | false | false | This domain represents the N-terminal region of GTP-binding HflX-like proteins [ , ]. These proteins interact with the 50S ribosome and are GTPases, hydrolysing GTP/GDP/ATP/ADP [ ]. The N-terminal region is necessary for stability of the whole protein. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13167"
] | [
"GTP-bdg_N"
] | [
28593
] | 1 | [] | [] | [] | 0 | [
"2qtf",
"2qth",
"3kxi",
"3kxk",
"3kxl",
"5ady",
"5zzm",
"7of2",
"7of4",
"7of6",
"7yla",
"8a57",
"8g31",
"8g34",
"8g38",
"8kab",
"8uu7",
"8uu8",
"8uu9",
"8uua",
"8vio",
"8vk0",
"8vk7",
"8vki",
"8vkw",
"8vpk",
"8vr4",
"8vr8",
"8vrl"
] | 29 | [
"PUB00056761",
"PUB00056762",
"PUB00057298"
] | [
"19109926",
"19824612",
"19181811"
] | [
"E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides.",
"Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach.",
"Properties of HflX, an enigmatic protein from Escherichia coli."
] | [
2009,
2009,
2009
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
804,
24556,
2706,
527
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
9,
1,
2,
2,
1,
3,
4,
5,
1,
12
] | 10 | true | Domain | GTPase HflX, N-terminal | GTPase HflX, N-terminal | GTPase_HflX_N | 6 |
IPR025122 | 25,122 | Domain of unknown function DUF4048 | DUF4048 | Domain | 1,021 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13257"
] | [
"DUF4048"
] | [
1021
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"saccharomyceta"
] | [
1021
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
2
] | 1 | true | Domain | Domain of unknown function DUF4048 | Domain of unknown function DUF4048 | DUF4048 | 5 |
IPR025123 | 25,123 | Domain of unknown function DUF4049 | DUF4049 | Domain | 377 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13258"
] | [
"DUF4049"
] | [
377
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Enterobacteriaceae",
"human gut metagenome"
] | [
369,
8
] | 2 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Domain | Domain of unknown function DUF4049 | Domain of unknown function DUF4049 | DUF4049 | 7 |
IPR025124 | 25,124 | Gag1-like, clamp domain | Gag1-like_clamp | Domain | 4,427 | false | false | This entry represents a domain found in a group of sequences from fungi and plants, including Gag1 from Saccharomyces cerevisiae (YLR407W), which interacts with Cka2, the fourth subunit of the eukaryotic kinase CK2. Gag1 is organised into three domains: lock, Gag and Clap (this entry). This domain, previously known as ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13259"
] | [
"clamp_Gag1-like"
] | [
4427
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00153176"
] | [
"37968396"
] | [
"The social and structural architecture of the yeast protein interactome."
] | [
2023
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pedobacter yonginense"
] | [
4426,
1
] | 2 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
29,
1,
6,
1,
1,
26
] | 6 | true | Domain | Gag1-like, clamp domain | Gag1-like, clamp domain | Gag1-like_clamp | 2 |
IPR025126 | 25,126 | Protein of unknown function DUF4052 | DUF4052 | Family | 159 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13261"
] | [
"DUF4052"
] | [
159
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati"
] | [
159
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4052 | Protein of unknown function DUF4052 | DUF4052 | 9 |
IPR025127 | 25,127 | Protein of unknown function DUF4054 | DUF4054 | Family | 2,086 | false | false | This family of proteins is functionally uncharacterised. Proteins in this family are found in bacteria and viruses. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13262"
] | [
"DUF4054"
] | [
2086
] | 1 | [] | [] | [] | 0 | [
"7kln",
"8fvh",
"8hdr",
"8hds",
"9b41",
"9jlf",
"9kmh",
"9l01"
] | 8 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Fungi",
"Stenosarchaea group",
"Viruses",
"metagenomes"
] | [
1511,
3,
2,
552,
18
] | 5 | [] | [] | 0 | true | Family | Protein of unknown function DUF4054 | Protein of unknown function DUF4054 | DUF4054 | 6 |
IPR025128 | 25,128 | Poxvirus B22R protein C-terminal domain | Poxvirus_B22R_C_dom | Domain | 273 | false | false | This domain represents a highly conserved region towards the C terminus of poxvirus proteins from Fowlpox virus, Myxoma virus, Lumpy skin disease, Variola virus and other members of the Poxviridae family of double-stranded, no-RNA stage poxviruses. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13168"
] | [
"Poxvirus_B22R_C"
] | [
273
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Viruses"
] | [
273
] | 1 | [] | [] | 0 | true | Domain | Poxvirus B22R protein C-terminal domain | Poxvirus B22R protein C-terminal domain | Poxvirus_B22R_C_dom | 4 |
IPR025129 | 25,129 | Domain of unknown function DUF4055 | DUF4055 | Domain | 1,439 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13264"
] | [
"DUF4055"
] | [
1439
] | 1 | [] | [] | [] | 0 | [
"8xb5",
"8xb6"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
1045,
4,
369,
21
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4055 | Domain of unknown function DUF4055 | DUF4055 | 9 |
IPR025130 | 25,130 | Protein of unknown function DUF4056 | DUF4056 | Family | 840 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13265"
] | [
"DUF4056"
] | [
840
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
838,
2
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4056 | Protein of unknown function DUF4056 | DUF4056 | 4 |
IPR025131 | 25,131 | Domain of unknown function DUF4057 | DUF4057 | Domain | 1,905 | false | false | This entry represents a domain found in a group of plant proteins, including DNA oxidative demethylase ALKBH2 from Arabidopsis thaliana , a dioxygenase that repairs alkylated DNA containing 1-methyladenine and 1-ethenoadenine by oxidative demethylation [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13266"
] | [
"DUF4057"
] | [
1905
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00101956"
] | [
"22532610"
] | [
"The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Heyndrickxia ginsengihumi",
"Viridiplantae"
] | [
1,
1904
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
27,
12,
49
] | 3 | true | Domain | Domain of unknown function DUF4057 | Domain of unknown function DUF4057 | DUF4057 | 8 |
IPR025132 | 25,132 | Protein of unknown function DUF4058 | DUF4058 | Family | 693 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13267"
] | [
"DUF4058"
] | [
693
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"unclassified sequences"
] | [
683,
5,
5
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4058 | Protein of unknown function DUF4058 | DUF4058 | 3 |
IPR025133 | 25,133 | Poxvirus B22R protein N-terminal domain | Poxvirus_B22R_N_dom | Domain | 256 | false | false | This domain represents the highly conserved N-terminal region of poxvirus proteins from Fowlpox virus, Myxoma virus, Lumpy skin disease, Variola virus and other members of the Poxviridae family of double-stranded, no-RNA stage poxviruses. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13169"
] | [
"Poxvirus_B22R_N"
] | [
256
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Poxviridae"
] | [
256
] | 1 | [] | [] | 0 | true | Domain | Poxvirus B22R protein N-terminal domain | Poxvirus B22R protein N-terminal domain | Poxvirus_B22R_N_dom | 5 |
IPR025134 | 25,134 | Protein of unknown function DUF4059 | DUF4059 | Family | 391 | false | false | This family of proteins is functionally uncharacterised. There is a conserved DKT sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13268"
] | [
"DUF4059"
] | [
391
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
391
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4059 | Protein of unknown function DUF4059 | DUF4059 | 9 |
IPR025137 | 25,137 | Bacteriophage N4 adsorption protein A, C-terminal | NfrA_C | Domain | 1,090 | false | false | The function of this domain is unknown, but it is found at the C terminus of bacteriophage N4 adsorption protein A (NfrA) in association with an N-terminal region of Tetratricopeptide (TPR) repeats. NfrA serves as the phage receptor [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13283"
] | [
"NfrA_C"
] | [
1090
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00057299"
] | [
"8226649"
] | [
"Two overlapping genes encoding membrane proteins required for bacteriophage N4 adsorption."
] | [
1993
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Rhizopus delemar",
"metagenomes"
] | [
1080,
1,
9
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Domain | Bacteriophage N4 adsorption protein A, C-terminal | Bacteriophage N4 adsorption protein A, C-terminal | NfrA_C | 1 |
IPR025138 | 25,138 | Domain of unknown function DUF4072 | DUF4072 | Domain | 649 | false | false | This short domain of unknown function is normally found at the N terminus of putative phosphoserine phosphatases. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13284"
] | [
"DUF4072"
] | [
649
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Linnemannia gamsii",
"Pseudomonadota",
"metagenomes"
] | [
1,
637,
11
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4072 | Domain of unknown function DUF4072 | DUF4072 | 3 |
IPR025140 | 25,140 | Putative 2/3 transmembrane domain holin | Holin_2-3 | Family | 633 | false | false | Holin_2-3 is a putative holins with 2 or 3 transmembrane segments. It consists of many proteobacterial proteins ranging in size from about 70 aas to 120 aas. They have 2 or 3 predicted TMSs. Although some are annotated as phage proteins or holins, none appears to be functionally characterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13272"
] | [
"Holin_2-3"
] | [
633
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Puccinia striiformis f. sp. tritici PST-78",
"metagenomes"
] | [
608,
21,
2,
2
] | 4 | [] | [] | 0 | true | Family | Putative 2/3 transmembrane domain holin | Putative 2/3 transmembrane domain holin | Holin_2-3 | 6 |
IPR025141 | 25,141 | Domain of unknown function DUF4082 | DUF4082 | Domain | 1,743 | false | false | This domain appears to be a parallel β-helix repeated region that is located between successive cadherin domains in some proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13313"
] | [
"DUF4082"
] | [
1743
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Arthrobacter phage Wildwest",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
1,
1726,
4,
12
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4082 | Domain of unknown function DUF4082 | DUF4082 | 4 |
IPR025142 | 25,142 | Domain of unknown function DUF4073 | DUF4073 | Domain | 435 | false | false | This domain is frequently found at the C terminus of bacterial proteins carrying the metallophosphoesterase domain . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13285"
] | [
"DUF4073"
] | [
435
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati",
"bioreactor metagenome"
] | [
434,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4073 | Domain of unknown function DUF4073 | DUF4073 | 1 |
IPR025143 | 25,143 | Protein of unknown function DUF4083 | DUF4083 | Family | 468 | false | false | This protein family is functionally uncharacterised. Some members are putatively annotated as being MutT/Nudix. However, the characteristic Nudix motif of GX(5)EX(7)REUXEE is absent. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13314"
] | [
"DUF4083"
] | [
468
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
468
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4083 | Protein of unknown function DUF4083 | DUF4083 | 7 |
IPR025145 | 25,145 | Protein of unknown function DUF4087 | DUF4087 | Family | 437 | false | false | This family of proteins is functionally uncharacterised. There is a conserved RCGW sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13316"
] | [
"DUF4087"
] | [
437
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"mine drainage metagenome"
] | [
436,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4087 | Protein of unknown function DUF4087 | DUF4087 | 7 |
IPR025146 | 25,146 | Protein of unknown function DUF4088 | DUF4088 | Family | 358 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13317"
] | [
"DUF4088"
] | [
358
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Burkholderiales"
] | [
358
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4088 | Protein of unknown function DUF4088 | DUF4088 | 7 |
IPR025147 | 25,147 | DNA packaging protein FI | Packaging_FI | Family | 767 | false | false | This family includes the lambda phage DNA-packaging protein FI [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14000"
] | [
"Packaging_FI"
] | [
767
] | 1 | [] | [] | [] | 0 | [
"2lsm"
] | 1 | [
"PUB00057300"
] | [
"8468297"
] | [
"Sites and gene products involved in lambdoid phage DNA packaging."
] | [
1993
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Methanobrevibacter smithii DSM 2375",
"human gut metagenome"
] | [
745,
19,
1,
2
] | 4 | [] | [] | 0 | true | Family | DNA packaging protein FI | DNA packaging protein FI | Packaging_FI | 1 |
IPR025149 | 25,149 | Protein of unknown function DUF4090 | DUF4090 | Family | 305 | false | false | This family of proteins is found in cyanobacteria and is functionally uncharacterised. Proteins in this family are approximately 90 amino acids in length. A member of this family, the ssr1528 gene was found to be regulated by an sRNA NsiR4 [ ]. In addition, the expression of that gene was repressed under conditions of ... | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF050008",
"PF13319"
] | [
"ssr1528_fam",
"DUF4090"
] | [
298,
305
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00088099"
] | [
"26494284"
] | [
"The sRNA NsiR4 is involved in nitrogen assimilation control in cyanobacteria by targeting glutamine synthetase inactivating factor IF7."
] | [
2015
] | 1 | [] | [] | 0 | 0 | null | [
"Cyanophyceae",
"marine metagenome"
] | [
304,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4090 | Protein of unknown function DUF4090 | DUF4090 | 8 |
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