interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR025262 | 25,262 | Quorum-sensing regulator protein G | QseG | Family | 1,504 | false | false | Quorum-sensing regulator protein G (QseG, also known as YfhG) is involved in the regulation of virulence and metabolism in enterohemorrhagic Escherichia coli (EHEC) [ ]. It is required for pedestal formation in host epithelial cells during infection and for translocation of effector molecules into host epithelial cells... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13942"
] | [
"Lipoprotein_20"
] | [
1504
] | 1 | [] | [] | [] | 0 | [
"7x6f",
"7x6g",
"7x6h"
] | 3 | [
"PUB00057322",
"PUB00057323"
] | [
"19289831",
"20056703"
] | [
"The two-component system QseEF and the membrane protein QseG link adrenergic and stress sensing to bacterial pathogenesis.",
"A transcriptome study of the QseEF two-component system and the QseG membrane protein in enterohaemorrhagic Escherichia coli O157 : H7."
] | [
2009,
2010
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Beauveria bassiana D1-5",
"human gut metagenome"
] | [
1502,
1,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Quorum-sensing regulator protein G | Quorum-sensing regulator protein G | QseG | 3 |
IPR025264 | 25,264 | Cag pathogenicity island protein Cag12 | Cag12 | Family | 569 | false | false | This is a Proteobacterial family of Cag pathogenicity island proteins [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13117"
] | [
"Cag12"
] | [
569
] | 1 | [] | [] | [] | 0 | [
"6oee",
"6x6k",
"6x6s",
"8ynx",
"8yo6"
] | 5 | [
"PUB00057386"
] | [
"16586107"
] | [
"Expression of Helicobacter pylori cag12 gene in Lactococcus lactis MG1363 and its oral administration to induce systemic anti-Cag12 immune response in mice."
] | [
2006
] | 1 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"bioreactor metagenome"
] | [
568,
1
] | 2 | [] | [] | 0 | true | Family | Cag pathogenicity island protein Cag12 | Cag pathogenicity island protein Cag12 | Cag12 | 9 |
IPR025265 | 25,265 | WPP domain | WPP_dom | Domain | 2,234 | false | false | The WPP domain is thought to be exclusively found in plants. The WPP stands for a tryptophan-proline-proline motif that is highly conserved in the domain [ ]. The WPP domain is known to direct RanGAP (Ran GTPase-activating protein) to the nuclear envelope [ ]. RanGAP is an accessory protein for the small signaling GTPa... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13943"
] | [
"WPP"
] | [
2234
] | 1 | [] | [] | [] | 0 | [
"4m70"
] | 1 | [
"PUB00057324",
"PUB00057325",
"PUB00057326"
] | [
"11115866",
"11752475",
"15548735"
] | [
"A novel link between ran signal transduction and nuclear envelope proteins in plants.",
"A domain unique to plant RanGAP is responsible for its targeting to the plant nuclear rim.",
"Arabidopsis WPP-domain proteins are developmentally associated with the nuclear envelope and promote cell division."
] | [
2000,
2001,
2004
] | 3 | [] | [] | 0 | 0 | null | [
"Viridiplantae"
] | [
2234
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
17,
14,
35
] | 3 | true | Domain | WPP domain | WPP domain | WPP_dom | 6 |
IPR025266 | 25,266 | TerB, N-terminal | TerB_N | Domain | 1,433 | false | false | This entry represents the N-terminal domain of TerB, and TerB-C containing proteins [ ]. It has a predominantly α-helical structure and contains an absolutely conserved glutamate [ ]. The presence of a conserved acidic residue suggests that it might chelate metal like TerB [ ]. These proteins occur in an two-gene opero... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13208"
] | [
"TerB_N"
] | [
1433
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00066658"
] | [
"23044854"
] | [
"Ter-dependent stress response systems: novel pathways related to metal sensing, production of a nucleoside-like metabolite, and DNA-processing."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanobacteriota",
"ecological metagenomes",
"rosids"
] | [
1407,
15,
9,
2
] | 4 | [] | [] | 0 | true | Domain | TerB, N-terminal | TerB, N-terminal | TerB_N | 6 |
IPR025267 | 25,267 | Major capsid protein ORF017-like | ORF017-like | Family | 895 | false | false | This entry, previously known as DUF4043, represents a group of proteins from tailed bacteriophages and prophages mainly found in proteobacteria and firmicutes, including Major capsid protein from Pseudomonas phage KPP25 (ORF017, ), Major capsid protein from Ralstonia phage GP4 [ ] and Major structural protein ORF14 fro... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13252"
] | [
"Phage_capsid_3"
] | [
895
] | 1 | [] | [] | [] | 0 | [
"7dn2",
"7eel",
"7f2p",
"8h89"
] | 4 | [
"PUB00089799",
"PUB00090172",
"PUB00151029"
] | [
"23475617",
"24801109",
"36366529"
] | [
"Characterization of Helicobacter pylori bacteriophage KHP30.",
"Characterization of a novel Pseudomonas aeruginosa bacteriophage, KPP25, of the family Podoviridae.",
"A Capsid Structure of <i>Ralstonia solanacearum</i> <i>podoviridae</i> GP4 with a Triangulation Number T = 9."
] | [
2013,
2014,
2022
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Gibberella intermedia",
"Viruses",
"metagenomes"
] | [
675,
1,
154,
65
] | 4 | [] | [] | 0 | true | Family | Major capsid protein ORF017-like | Major capsid protein ORF017-like | ORF017-like | 6 |
IPR025269 | 25,269 | Phage integrase SAM-like domain | SAM-like_dom | Domain | 24,845 | false | false | This domain was originally identified by clustering human gut metagenomic sequences [ ]. It appears related to the N-terminal domain of phage integrases. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13102"
] | [
"Phage_int_SAM_5"
] | [
24845
] | 1 | [] | [] | [] | 0 | [
"2key"
] | 1 | [
"PUB00055601"
] | [
"20532204"
] | [
"Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families."
] | [
2010
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
247,
23767,
18,
167,
646
] | 5 | [] | [] | 0 | true | Domain | Phage integrase SAM-like domain | Phage integrase SAM-like domain | SAM-like_dom | 8 |
IPR025270 | 25,270 | Protein of unknown function DUF4044 | DUF4044 | Family | 841 | false | false | This family of proteins is functionally uncharacterised. There is a single completely conserved residue M that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13253"
] | [
"DUF4044"
] | [
841
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"bioreactor metagenome"
] | [
840,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4044 | Protein of unknown function DUF4044 | DUF4044 | 1 |
IPR025271 | 25,271 | Coiled-coil domain-containing protein 28 | CCDC28 | Family | 2,580 | false | false | This entry includes CCDC28A and CCDC28B. CCDC28B modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation [ ]. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF13270",
"PTHR13400"
] | [
"CCDC28",
""
] | [
2572,
2397
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00092906"
] | [
"23727834"
] | [
"The Bardet-Biedl syndrome-related protein CCDC28B modulates mTORC2 function and interacts with SIN1 to control cilia length independently of the mTOR complex."
] | [
2013
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2580
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
4,
8,
10,
9
] | 5 | true | Family | Coiled-coil domain-containing protein 28 | Coiled-coil domain-containing protein 28 | CCDC28 | 6 |
IPR025272 | 25,272 | Antitoxin SocA-like, Panacea domain | SocA_Panacea | Domain | 5,918 | false | false | This entry represents a domain found centrally in Antitoxin SocA from Caulobacter vibrioides. SocA is the antitoxin component of an atypical type II toxin-antitoxin (TA) system which neutralises the toxic activity of toxin SocB by acting as an adapter to promote its degradation by the protease ClpXP [ ]. The Panacea do... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13274"
] | [
"SocA_Panacea"
] | [
5918
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00100160",
"PUB00100422"
] | [
"24239291",
"35121656"
] | [
"A bacterial toxin inhibits DNA replication elongation through a direct interaction with the β sliding clamp.",
"A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains."
] | [
2013,
2022
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
135,
5591,
18,
49,
125
] | 5 | [] | [] | 0 | true | Domain | Antitoxin SocA-like, Panacea domain | Antitoxin SocA-like, Panacea domain | SocA_Panacea | 5 |
IPR025273 | 25,273 | Domain of unknown function DUF4064 | DUF4064 | Domain | 1,727 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13273"
] | [
"DUF4064"
] | [
1727
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Panagrolaimus davidi",
"Waukeshavirus waukesha92",
"human gut metagenome"
] | [
21,
1701,
1,
2,
2
] | 5 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4064 | Domain of unknown function DUF4064 | DUF4064 | 7 |
IPR025274 | 25,274 | Domain of unknown function DUF4070 | DUF4070 | Domain | 2,262 | false | false | This is a bacterial domain often found at the C terminus of radical SAM methylases. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13282"
] | [
"DUF4070"
] | [
2262
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"metagenomes"
] | [
2174,
2,
86
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4070 | Domain of unknown function DUF4070 | DUF4070 | 1 |
IPR025275 | 25,275 | Putative glycosyl hydrolase domain DUF4015 | DUF4015 | Domain | 3,106 | false | false | This domain is related to known glycosyl hydrolase domains, suggesting it is involved in carbohydrate breakdown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13200"
] | [
"DUF4015"
] | [
3106
] | 1 | [] | [] | [] | 0 | [
"4s1a"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
80,
2961,
4,
61
] | 4 | [] | [] | 0 | true | Domain | Putative glycosyl hydrolase domain DUF4015 | Putative glycosyl hydrolase domain DUF4015 | DUF4015 | 7 |
IPR025276 | 25,276 | Protein of unknown function DUF4075 | DUF4075 | Family | 159 | false | false | This family of proteins is functionally uncharacterised. Some members are annotated as putative mature parasite-infected erythrocyte surface antigen protein from Bacillus spp. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13294"
] | [
"DUF4075"
] | [
159
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus"
] | [
159
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4075 | Protein of unknown function DUF4075 | DUF4075 | 9 |
IPR025277 | 25,277 | Apiosidase-like, catalytic domain | Apiosidase-like_cat_dom | Domain | 3,697 | false | false | This entry represents the catalytic domain of endo-apiosidase (GH140, ) and related proteins some of which form part of the rhamnogalacturonan-II (RG-II) degradome. This domain adopts an (α/β)8-barrel that harbours the aspartate and glutamate residues essential for the catalytic activity [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13204"
] | [
"Apiosidase"
] | [
3697
] | 1 | [] | [] | [] | 0 | [
"3kzs",
"4n0r",
"4qfu",
"5msy",
"8t9w"
] | 5 | [
"PUB00103952"
] | [
"28329766"
] | [
"Complex pectin metabolism by gut bacteria reveals novel catalytic functions."
] | [
2017
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
21,
3232,
394,
50
] | 4 | [] | [] | 0 | true | Domain | Apiosidase-like, catalytic domain | Apiosidase-like, catalytic domain | Apiosidase-like_cat_dom | 5 |
IPR025278 | 25,278 | Domain of unknown function DUF4077 | DUF4077 | Domain | 185 | false | false | This functionally uncharacterised domain is found in the N-terminal region of sequences annotated as methyl-accepting chemotaxis proteins from Bacillus spp. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13295"
] | [
"DUF4077"
] | [
185
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales",
"Trichobilharzia regenti"
] | [
184,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4077 | Domain of unknown function DUF4077 | DUF4077 | 1 |
IPR025279 | 25,279 | Stress response protein NST1 | NST1 | Family | 1,799 | false | false | NST1 is a family of proteins that seem to be involved, directly or indirectly, in the salt sensitivity of some cellular functions in yeast. It does this without affecting sodium accumulation. It negatively affects salt-tolerance through an interaction with the splicing factor Msl1p. This interaction stresses the import... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13945"
] | [
"NST1"
] | [
1799
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00057327"
] | [
"11816027"
] | [
"Involvement of Nst1p/YNL091w and Msl1p, a U2B'' splicing factor, in Saccharomyces cerevisiae salt tolerance."
] | [
2002
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Floridaenema evergladense BLCC-F167"
] | [
1798,
1
] | 2 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1,
1
] | 3 | true | Family | Stress response protein NST1 | Stress response protein NST1 | NST1 | 3 |
IPR025280 | 25,280 | SNIPE associated domain | SNIPE | Domain | 1,612 | false | false | This entry represents the SNIPE associated domain, a small largely α-helical domain found in the SNIPE protein family. SNIPE proteins cleave phage DNA during genome injection. This domain may help SNIPE bind to phage DNA. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13250"
] | [
"SNIPE"
] | [
1612
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Methanobacteriota",
"ecological metagenomes"
] | [
1574,
19,
11,
8
] | 4 | [] | [] | 0 | true | Domain | SNIPE associated domain | SNIPE associated domain | SNIPE | 3 |
IPR025281 | 25,281 | Domain of unknown function DUF4074 | DUF4074 | Domain | 2,498 | false | false | This functionally uncharacterised domain is found at the C-terminal of a number of metazoan homeobox proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13293"
] | [
"DUF4074"
] | [
2498
] | 1 | [
"REACTOME"
] | [
"R-HSA-5617472"
] | [
"REACTOME:R-HSA-5617472"
] | 1 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Vertebrata"
] | [
2498
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
10,
7,
4,
6
] | 4 | true | Domain | Domain of unknown function DUF4074 | Domain of unknown function DUF4074 | DUF4074 | 2 |
IPR025282 | 25,282 | Domain of unknown function DUF4214 | DUF4214 | Domain | 4,138 | false | false | This domain of unknown function is found on a variety of different proteins, including transferases and allergen V5/Tpx-1 related proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13946"
] | [
"DUF4214"
] | [
4138
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"ecological metagenomes"
] | [
18,
4008,
36,
14,
62
] | 5 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4214 | Domain of unknown function DUF4214 | DUF4214 | 2 |
IPR025284 | 25,284 | Protein of unknown function DUF4144 | DUF4144 | Family | 398 | false | false | The function of these proteins is not known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13642"
] | [
"DUF4144"
] | [
398
] | 1 | [] | [] | [] | 0 | [
"2l6o"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"marine sediment metagenome"
] | [
397,
1
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4144 | Protein of unknown function DUF4144 | DUF4144 | 4 |
IPR025286 | 25,286 | MOFRL-associated domain | MOFRL_assoc_dom | Domain | 8,868 | false | false | This domain is frequently found at the N terminus of proteins that carrying the MOFRL domain ( ), some of which are glycerate kinases [ , ]. However, proteins matched by this entry do not have flavodoxin-like domain ( ) or restriction-enzyme-like fold ( ), which can be found in other type of glycerate kinases ( ). | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13660"
] | [
"DUF4147"
] | [
8868
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.7.1",
"R-BTA-70350",
"R-CEL-70350",
"R-DME-70350",
"R-DRE-70350",
"R-HSA-70350",
"R-MMU-70350",
"R-RNO-70350"
] | [
"EC:2.7.1",
"REACTOME:R-BTA-70350",
"REACTOME:R-CEL-70350",
"REACTOME:R-DME-70350",
"REACTOME:R-DRE-70350",
"REACTOME:R-HSA-70350",
"REACTOME:R-MMU-70350",
"REACTOME:R-RNO-70350"
] | 8 | [
"1x3l",
"2b8n"
] | 2 | [
"PUB00066956",
"PUB00066957"
] | [
"18156253",
"20949620"
] | [
"Glycerate 2-kinase of Thermotoga maritima and genomic reconstruction of related metabolic pathways.",
"D-glyceric aciduria is caused by genetic deficiency of D-glycerate kinase (GLYCTK)."
] | [
2008,
2010
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
638,
6173,
1922,
135
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
47,
2,
4,
6,
2
] | 6 | true | Domain | MOFRL-associated domain | MOFRL-associated domain | MOFRL_assoc_dom | 4 |
IPR025287 | 25,287 | Wall-associated receptor kinase, galacturonan-binding domain | WAK_GUB | Domain | 35,272 | false | false | Wall-associated kinases (WAKs) are transmembrane proteins containing a cytoplasmic serine/threonine kinase domain and an extracellular domain in contact with the pectin fraction of the plant cell wall [ ]. The cysteine-rich galacturonan-binding domain is located near the N-terminal end of the extracellular domain and b... | [
"GO:0030247"
] | [
"polysaccharide binding"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF13947"
] | [
"GUB_WAK_bind"
] | [
35272
] | 1 | [
"EC"
] | [
"2.7.11"
] | [
"EC:2.7.11"
] | 1 | [] | 0 | [
"PUB00057328",
"PUB00057329",
"PUB00057330"
] | [
"16631829",
"10380805",
"15769808"
] | [
"In vitro characterization of the homogalacturonan-binding domain of the wall-associated kinase WAK1 using site-directed mutagenesis.",
"A cluster of five cell wall-associated receptor kinase genes, Wak1-5, are expressed in specific organs of Arabidopsis.",
"Wall-associated kinase WAK1 interacts with cell wall ... | [
2006,
1999,
2005
] | 3 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
35272
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
220,
445,
311
] | 3 | true | Domain | Wall-associated receptor kinase, galacturonan-binding domain | Wall-associated receptor kinase, galacturonan-binding domain | WAK_GUB | 8 |
IPR025288 | 25,288 | Domain of unknown function DUF4080 | DUF4080 | Domain | 3,061 | false | false | This presumed domain is found at the C terminus of a number of sequences annotated as radical SAM methylthiotransferases. The domain is functionally uncharacterised. It was found by clustering human gut metagenomic sequences [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13311"
] | [
"DUF4080"
] | [
3061
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00055601"
] | [
"20532204"
] | [
"Expansion of the protein repertoire in newly explored environments: human gut microbiome specific protein families."
] | [
2010
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Myoviridae sp. ctcaJ26",
"metagenomes"
] | [
3007,
4,
1,
49
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4080 | Domain of unknown function DUF4080 | DUF4080 | 6 |
IPR025291 | 25,291 | Protein of unknown function DUF4153 | DUF4153 | Family | 6,576 | false | false | This family consists of putative membrane proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13687"
] | [
"DUF4153"
] | [
6576
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"metagenomes"
] | [
6516,
5,
55
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF4153 | Protein of unknown function DUF4153 | DUF4153 | 4 |
IPR025293 | 25,293 | YfiR/HmsC-like | YfiR/HmsC-like | Family | 4,285 | false | false | YfiR has been shown to regulate YfiN, a diguanylate cyclase and a bifunctional protein that produces c-di-GMP in response to reductive stress and then dynamically relocates to the division site to arrest cell division in response to envelope stress in Escherichia coli. YfiR may serve as a periplasmic redox sensor that ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13689"
] | [
"DUF4154"
] | [
4285
] | 1 | [] | [] | [] | 0 | [
"4xjy",
"4yn7",
"4yn9",
"4yna",
"4zhu",
"4zhy",
"5eb1",
"5eb2",
"5eb3",
"5y61",
"5y62",
"6ikk"
] | 12 | [
"PUB00088309",
"PUB00088310",
"PUB00091013",
"PUB00091014"
] | [
"27507823",
"25849887",
"25586342",
"24192006"
] | [
"A Diguanylate Cyclase Acts as a Cell Division Inhibitor in a Two-Step Response to Reductive and Envelope Stresses.",
"Crystal structures of YfiR from Pseudomonas aeruginosa in two redox states.",
"The Yersinia pestis HmsCDE regulatory system is essential for blockage of the oriental rat flea (Xenopsylla cheopi... | [
2016,
2015,
2015,
2014
] | 4 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
4242,
3,
40
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | YfiR/HmsC-like | YfiR/HmsC-like | YfiR/HmsC-like | 2 |
IPR025294 | 25,294 | Protein of unknown function DUF4156 | DUF4156 | Family | 2,569 | false | false | The function of this family is unknown but some members are annotated as putative lipoprotein outer membrane proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13698"
] | [
"DUF4156"
] | [
2569
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
2549,
3,
17
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF4156 | Protein of unknown function DUF4156 | DUF4156 | 1 |
IPR025295 | 25,295 | eCIS core domain | eCIS_core_dom | Domain | 6,291 | false | false | This entry represents a domain found in a group of prokaryotic proteins that was previously known as DUF4157. This domain has been recently identified as a highly conserved eCIS (extracellular Contractile Injection System) core domain [ ]. eCIS is a cell-free toxin-delivery system that evolved from a bacteriophage tail... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13699"
] | [
"eCIS_core"
] | [
6291
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00100134",
"PUB00154361",
"PUB00160456"
] | [
"31577948",
"34145238",
"39546591"
] | [
"The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology.",
"The extracellular contractile injection system is enriched in environmental microbes and associates with numerous toxins.",
"Archaeal type six secretion system mediates contact-dependent antagonism."
] | [
2019,
2021,
2024
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified Caudoviricetes",
"unclassified sequences"
] | [
311,
5932,
7,
3,
38
] | 5 | [] | [] | 0 | true | Domain | eCIS core domain | eCIS core domain | eCIS_core_dom | 7 |
IPR025297 | 25,297 | Domain of unknown function DUF4159 | DUF4159 | Domain | 5,462 | false | false | This is a domain of unknown function found in bacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13709"
] | [
"DUF4159"
] | [
5462
] | 1 | [] | [] | [] | 0 | [
"4i66"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
5290,
11,
161
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4159 | Domain of unknown function DUF4159 | DUF4159 | 2 |
IPR025298 | 25,298 | Domain of unknown function DUF4094 | DUF4094 | Domain | 5,522 | false | false | This domain is found in a number of proteins, including eleven beta-1,3-galactosyltransferases paralogues from Arabidopsis thaliana. Beta-1,3-galactosyltransferase transfers galactose from UDP-galactose to substrates with a terminal glycosyl residue [ ]. This domain is found in N-terminal domain of the beta-1,3-galacto... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13334"
] | [
"DUF4094"
] | [
5522
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"... | [
"2.4.1.-",
"PWY-1901",
"PWY-1961",
"PWY-1981",
"PWY-2021",
"PWY-2881",
"PWY-2901",
"PWY-2902",
"PWY-4421",
"PWY-4801",
"PWY-5094",
"PWY-5105",
"PWY-5129",
"PWY-5139",
"PWY-5160",
"PWY-5161",
"PWY-5268",
"PWY-5284",
"PWY-5286",
"PWY-5310",
"PWY-5312",
"PWY-5313",
"PWY-5317... | [
"EC:2.4.1.-",
"METACYC:PWY-1901",
"METACYC:PWY-1961",
"METACYC:PWY-1981",
"METACYC:PWY-2021",
"METACYC:PWY-2881",
"METACYC:PWY-2901",
"METACYC:PWY-2902",
"METACYC:PWY-4421",
"METACYC:PWY-4801",
"METACYC:PWY-5094",
"METACYC:PWY-5105",
"METACYC:PWY-5129",
"METACYC:PWY-5139",
"METACYC:PWY-5... | 200 | [] | 0 | [
"PUB00066872"
] | [
"18548197"
] | [
"Identification of a novel group of putative Arabidopsis thaliana beta-(1,3)-galactosyltransferases."
] | [
2008
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pasteurella testudinis DSM 23072"
] | [
5521,
1
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
55,
26,
59
] | 3 | true | Domain | Domain of unknown function DUF4094 | Domain of unknown function DUF4094 | DUF4094 | 4 |
IPR025300 | 25,300 | Beta-galactosidase jelly roll domain | BetaGal_jelly_roll_dom | Domain | 5,066 | false | false | This domain is found in beta-galactosidase enzymes, mainly from the glycosyl hydrolase 35 family. It has a jelly roll fold [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13364"
] | [
"BetaGal_ABD2"
] | [
5066
] | 1 | [
"EC",
"METACYC"
] | [
"3.2.1.23",
"PWY-6807"
] | [
"EC:3.2.1.23",
"METACYC:PWY-6807"
] | 2 | [
"1tg7",
"1xc6",
"3og2",
"3ogr",
"3ogs",
"3ogv",
"4iug",
"5ifp",
"5ift",
"5ihr",
"5juv",
"5mgc",
"5mgd",
"7kmm"
] | 14 | [
"PUB00031444"
] | [
"15491613"
] | [
"Crystal structures of beta-galactosidase from Penicillium sp. and its complex with galactose."
] | [
2004
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
16,
1277,
3763,
10
] | 4 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Zea mays"
] | [
2,
2,
10
] | 3 | true | Domain | Beta-galactosidase jelly roll domain | Beta-galactosidase jelly roll domain | BetaGal_jelly_roll_dom | 6 |
IPR025302 | 25,302 | Daunorubicin resistance ATP-binding protein DrrA1/2-like, C-terminal domain | DrrA1/2-like_C | Domain | 26,004 | false | false | This domain is found at the C-terminal end of Daunorubicin resistance ATP-binding protein DrrA1/2 from Streptomyces coeruleorubidus, Multidrug efflux system ATP-binding protein Rv1218c from Mycobacterium tuberculosis, some putative ABC transporter proteins and related prokaryotic sequences. DrrA1/2 are part of the ABC ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13732"
] | [
"DrrA1-3_C"
] | [
26004
] | 1 | [] | [] | [] | 0 | [
"4yer",
"8k1m",
"8k1n",
"8k1o",
"8k1p"
] | 5 | [
"PUB00158909",
"PUB00158930",
"PUB00158931"
] | [
"39375957",
"20921309",
"23143285"
] | [
"The involvement of multiple ABC transporters in daunorubicin efflux in Streptomyces coeruleorubidus.",
"Rv1218c, an ABC transporter of Mycobacterium tuberculosis with implications in drug discovery.",
"The expression of ABC efflux pump, Rv1217c-Rv1218c, and its association with multidrug resistance of Mycobact... | [
2024,
2010,
2013
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Siphoviridae sp. ctBLh2",
"unclassified sequences"
] | [
1964,
23685,
24,
1,
330
] | 5 | [] | [] | 0 | true | Domain | Daunorubicin resistance ATP-binding protein DrrA1/2-like, C-terminal domain | Daunorubicin resistance ATP-binding protein DrrA1/2-like, C-terminal domain | DrrA1/2-like_C | 3 |
IPR025303 | 25,303 | Deacetylase PdaC | PdaC | Domain | 4,290 | false | false | This domain forms an α/β-two layer sandwich. It is found in the Bacillus subtilis proteins anti-sigma-V factor RsiV, which downregulates SigV activity [ ], and peptidoglycan-N-acetylmuramic acid deacetylase PdaC, which catalyσes the deacetylation of N-acetylmuramic acid which makes the peptidoglycan resistant to lysozy... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13739"
] | [
"PdaC"
] | [
4290
] | 1 | [] | [] | [] | 0 | [
"3cyg",
"3s5t",
"5jen"
] | 3 | [
"PUB00084362",
"PUB00084363"
] | [
"16274938",
"22277649"
] | [
"Identification of sigma(V)-dependent genes of Bacillus subtilis.",
"Identification and characterization of a novel polysaccharide deacetylase C (PdaC) from Bacillus subtilis."
] | [
2005,
2012
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Methanolliviera hydrocarbonicum",
"Eukaryota",
"metagenomes"
] | [
4246,
1,
2,
41
] | 4 | [] | [] | 0 | true | Domain | Deacetylase PdaC | Deacetylase PdaC | PdaC | 2 |
IPR025304 | 25,304 | ALIX V-shaped domain | ALIX_V_dom | Domain | 9,126 | false | false | The binding of the LYPxL motif of late HIV p6Gag and EIAV p9Gag to this domain is necessary for viral budding. In ALIX, a component of the ESCRT pathway, this domain is central between an N-terminal Bro1 domain ( ) and a C-terminal proline-rich domain. The ALIX central domain is formed by two three-helix bundles dispos... | [
"GO:0005515"
] | [
"protein binding"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF13949"
] | [
"ALIX_LYPXL_bnd"
] | [
9126
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-162588",
"R-HSA-5210891",
"R-HSA-5213460",
"R-HSA-5675482",
"R-HSA-9008059",
"R-MMU-5213460",
"R-MMU-5675482",
"R-RNO-5213460",
"R-RNO-5675482"
] | [
"REACTOME:R-HSA-162588",
"REACTOME:R-HSA-5210891",
"REACTOME:R-HSA-5213460",
"REACTOME:R-HSA-5675482",
"REACTOME:R-HSA-9008059",
"REACTOME:R-MMU-5213460",
"REACTOME:R-MMU-5675482",
"REACTOME:R-RNO-5213460",
"REACTOME:R-RNO-5675482"
] | 9 | [
"2oev",
"2oex",
"2ojq",
"2r02",
"2r03",
"2r05",
"2xs1",
"2xs8",
"4jio",
"4jjy",
"5lm1",
"5lm2"
] | 12 | [
"PUB00042168",
"PUB00042214",
"PUB00049203"
] | [
"17350572",
"17277784",
"18066081"
] | [
"Structural and biochemical studies of ALIX/AIP1 and its role in retrovirus budding.",
"Structural basis for viral late-domain binding to Alix.",
"Structural and functional studies of ALIX interactions with YPX(n)L late domains of HIV-1 and EIAV."
] | [
2007,
2007,
2008
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"bird metagenome"
] | [
9125,
1
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
2,
3,
6,
3,
8,
4,
2,
6,
7,
2,
1,
17
] | 12 | true | Domain | ALIX V-shaped domain | ALIX V-shaped domain | ALIX_V_dom | 1 |
IPR025306 | 25,306 | Probable zinc-binding domain | Zn-bnd_dom_prob | Domain | 2,301 | false | false | This entry represents a probable zinc-binding domain with two CxxC sequence motifs. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13451"
] | [
"zf_Tbcl"
] | [
2301
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanosarcinales",
"metagenomes",
"unclassified Caudoviricetes"
] | [
2075,
122,
5,
96,
3
] | 5 | [] | [] | 0 | true | Domain | Probable zinc-binding domain | Probable zinc-binding domain | Zn-bnd_dom_prob | 2 |
IPR025307 | 25,307 | FIIND domain | FIIND_dom | Domain | 4,186 | false | false | This entry contains the whole FIIND domain composed by the ZU5 sub-domain and the UPA sub-domain . The so-called function-to-find (FIIND) domain was initially identified in two proteins: NLRP1 (also known as NALP1, CARD7, NAC, DEFCAP) and CARD8 (also known as TUCAN, Cardinal) [ ]. NLRP1 is a member of the Nod-like rece... | [] | [] | [] | 0 | [
"PFAM",
"PFAM",
"PROFILE"
] | [
"PF13553",
"PF23679",
"PS51830"
] | [
"FIIND",
"UPA-FIIND",
"FIIND"
] | [
4017,
3409,
4107
] | 3 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DRE-844456",
"R-HSA-111458",
"R-HSA-844455",
"R-HSA-9627069",
"R-MMU-844455",
"R-RNO-844455"
] | [
"REACTOME:R-DRE-844456",
"REACTOME:R-HSA-111458",
"REACTOME:R-HSA-844455",
"REACTOME:R-HSA-9627069",
"REACTOME:R-MMU-844455",
"REACTOME:R-RNO-844455"
] | 6 | [
"6x6a",
"6x6c",
"7crv",
"7crw",
"7jkq",
"7jn7"
] | 6 | [
"PUB00043499",
"PUB00057331",
"PUB00057332",
"PUB00057333",
"PUB00100103"
] | [
"11076957",
"11408476",
"12563287",
"12191486",
"34061031"
] | [
"Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteins.",
"TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.",
"NALPs: a novel protein family involved in inflammation.",
... | [
2001,
2001,
2003,
2002,
2021
] | 5 | [] | [] | 0 | 0 | null | [
"Chordata",
"Infectious spleen and kidney necrosis virus"
] | [
4172,
14
] | 2 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
52,
32,
12,
14
] | 4 | true | Domain | FIIND domain | FIIND domain | FIIND_dom | 4 |
IPR025309 | 25,309 | KTSC domain | KTSC_dom | Domain | 4,775 | false | false | This short domain is named after lysine tRNA synthetase C-terminal domain. It is found at the C terminus of some lysyl tRNA synthetases and also as a single domain protein in bacterial proteins. The domain is about 60 amino acids in length and contains a reasonably conserved YXY motif in the centre of the sequence. The... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13619"
] | [
"KTSC"
] | [
4775
] | 1 | [
"EC"
] | [
"6.1.1.6"
] | [
"EC:6.1.1.6"
] | 1 | [
"4rgi",
"7x8c",
"8wiv",
"8wj3",
"8wk0",
"8wld",
"8woc",
"8wod",
"8wof"
] | 9 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
121,
4427,
5,
130,
92
] | 5 | [] | [] | 0 | true | Domain | KTSC domain | KTSC domain | KTSC_dom | 4 |
IPR025310 | 25,310 | Protein of unknown function DUF4164 | DUF4164 | Family | 1,187 | false | false | This protein family of unknown function contains several conserved LE/LD sequence pairs. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13747"
] | [
"DUF4164"
] | [
1187
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Hevea brasiliensis",
"ecological metagenomes"
] | [
1176,
1,
10
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4164 | Protein of unknown function DUF4164 | DUF4164 | 1 |
IPR025311 | 25,311 | Domain of unknown function DUF4166 | DUF4166 | Domain | 2,972 | false | false | This domain of unknown function is found in bacterial proteins, such as the uncharacterised protein YndH from Bacillus subtilis. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13761"
] | [
"DUF4166"
] | [
2972
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halobacteriales",
"metagenomes"
] | [
2830,
48,
67,
27
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4166 | Domain of unknown function DUF4166 | DUF4166 | 4 |
IPR025312 | 25,312 | Domain of unknown function DUF4216 | DUF4216 | Domain | 8,480 | false | false | The function of this domain is not known. It is found in a number of putative transposases. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13952"
] | [
"DUF4216"
] | [
8480
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
3,
8477
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
27,
523,
10
] | 3 | true | Domain | Domain of unknown function DUF4216 | Domain of unknown function DUF4216 | DUF4216 | 7 |
IPR025313 | 25,313 | ATP-dependent rRNA helicase SPB4-like, C-terminal extension | SPB4-like_CTE | Domain | 18,838 | false | false | This short domain is found towards the C-terminal of many eukaryotic helicases, including some DEAD box helicases such as ATP-dependent rRNA helicase SPB4 from Saccharomyces cerevisiae. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome... | [] | [] | [] | 0 | [
"PFAM",
"SMART"
] | [
"PF13959",
"SM01178"
] | [
"CTE_SPB4",
"DUF4217"
] | [
18611,
18785
] | 2 | [
"EC"
] | [
"3.6.4.13"
] | [
"EC:3.6.4.13"
] | 1 | [
"5z3g",
"6c0f",
"6cb1",
"6elz",
"6em1",
"6em3",
"6em4",
"6em5",
"7nac",
"7nad",
"7ohp",
"7ohr",
"7ohs",
"7ohv",
"7ohw",
"7ohx",
"7r6q",
"7r72",
"7r7a",
"8e5t",
"8esq",
"8esr",
"8etg",
"8eth",
"8eti",
"8eup",
"8euy",
"8ev3",
"8fkp",
"8fkq",
"8fkr",
"8fks"... | 50 | [
"PUB00153742"
] | [
"36482249"
] | [
"Sequence-specific remodeling of a topologically complex RNP substrate by Spb4."
] | [
2022
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
18838
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
33,
6,
6,
6,
16,
14,
4,
8,
13,
4,
4,
31
] | 12 | true | Domain | ATP-dependent rRNA helicase SPB4-like, C-terminal extension | ATP-dependent rRNA helicase SPB4-like, C-terminal extension | SPB4-like_CTE | 2 |
IPR025314 | 25,314 | Domain of unknown function DUF4219 | DUF4219 | Domain | 2,291 | false | false | This domain is very short and is found at the N-terminal of many Gag-pol polyproteins from retrotransposons and related sequences. There is a highly conserved YxxWxxxM sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13961"
] | [
"DUF4219"
] | [
2291
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2291
] | 1 | [
"Arabidopsis thaliana",
"Drosophila melanogaster",
"Oryza sativa subsp. japonica"
] | [
3,
2,
27
] | 3 | true | Domain | Domain of unknown function DUF4219 | Domain of unknown function DUF4219 | DUF4219 | 1 |
IPR025315 | 25,315 | Domain of unknown function DUF4220 | DUF4220 | Domain | 11,472 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13968"
] | [
"DUF4220"
] | [
11472
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
11472
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
42,
344,
146
] | 3 | true | Domain | Domain of unknown function DUF4220 | Domain of unknown function DUF4220 | DUF4220 | 4 |
IPR025316 | 25,316 | Protein of unknown function DUF4221 | DUF4221 | Family | 1,431 | false | false | This protein family contains highly conserved asparagine and cysteine residues. The function is not known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13970"
] | [
"DUF4221"
] | [
1431
] | 1 | [] | [] | [] | 0 | [
"3s9j"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
1422,
9
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4221 | Protein of unknown function DUF4221 | DUF4221 | 1 |
IPR025317 | 25,317 | Protein of unknown function DUF4222 | DUF4222 | Family | 1,625 | false | false | These short proteins are largely found in enteric bacteria and are likely to be of phage origin. Their molecular function is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13973"
] | [
"DUF4222"
] | [
1625
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"bioreactor metagenome"
] | [
1608,
16,
1
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4222 | Protein of unknown function DUF4222 | DUF4222 | 9 |
IPR025318 | 25,318 | Protein of unknown function DUF4223 | DUF4223 | Family | 674 | false | false | This family of proteins is functionally uncharacterised. Proteins in this family are approximately 60 amino acids in length and are predicted to be to be lipoproteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13978"
] | [
"DUF4223"
] | [
674
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
672,
2
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF4223 | Protein of unknown function DUF4223 | DUF4223 | 2 |
IPR025320 | 25,320 | Protein of unknown function DUF4225 | DUF4225 | Family | 1,035 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13988"
] | [
"DUF4225"
] | [
1035
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Lucilia cuprina",
"Viruses"
] | [
1032,
1,
2
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4225 | Protein of unknown function DUF4225 | DUF4225 | 1 |
IPR025321 | 25,321 | Protein of unknown function DUF4227 | DUF4227 | Family | 1,152 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14004"
] | [
"DUF4227"
] | [
1152
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
1152
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4227 | Protein of unknown function DUF4227 | DUF4227 | 5 |
IPR025322 | 25,322 | PADRE domain | PADRE_dom | Family | 16,931 | false | false | This entry represents the Pathogen and abiotic stress response, cadmium tolerance, disordered region-containing (PADRE) domain, which is specifically found in plants. PADRE typically occurs in small single-domain proteins with a bipartite architecture. PADRE contains conserved sequence motifs at the N-terminal, and its... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14009"
] | [
"PADRE"
] | [
16931
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00098607"
] | [
"32547597"
] | [
"Patterns of Sequence and Expression Diversification Associate Members of the <i>PADRE</i> Gene Family With Response to Fungal Pathogens."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
16931
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
113,
112,
145
] | 3 | true | Family | PADRE domain | PADRE domain | PADRE_dom | 5 |
IPR025323 | 25,323 | Protein of unknown function DUF4229 | DUF4229 | Family | 3,884 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14012"
] | [
"DUF4229"
] | [
3884
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
3843,
2,
39
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4229 | Protein of unknown function DUF4229 | DUF4229 | 9 |
IPR025324 | 25,324 | Protein of unknown function DUF4230 | DUF4230 | Family | 5,818 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14014"
] | [
"DUF4230"
] | [
5818
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
5776,
4,
38
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4230 | Protein of unknown function DUF4230 | DUF4230 | 1 |
IPR025325 | 25,325 | Protein of unknown function DUF4231 | DUF4231 | Family | 1,550 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14015"
] | [
"DUF4231"
] | [
1550
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
12,
1413,
79,
14,
32
] | 5 | [] | [] | 0 | true | Family | Protein of unknown function DUF4231 | Protein of unknown function DUF4231 | DUF4231 | 2 |
IPR025326 | 25,326 | Domain of unknown function DUF4232 | DUF4232 | Domain | 7,725 | false | false | This entry represents a domain of unknown function found in uncharacterised bacterial proteins, many of which are thought to be lipoproteins. This domain may adopt a Ig-like fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14016"
] | [
"DUF4232"
] | [
7725
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Lasius niger",
"ecological metagenomes"
] | [
7713,
1,
11
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4232 | Domain of unknown function DUF4232 | DUF4232 | 5 |
IPR025328 | 25,328 | Domain of unknown function DUF4234 | DUF4234 | Domain | 1,375 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14018"
] | [
"DUF4234"
] | [
1375
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Geodia barretti",
"ecological metagenomes"
] | [
36,
1314,
1,
24
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4234 | Domain of unknown function DUF4234 | DUF4234 | 6 |
IPR025329 | 25,329 | Protein of unknown function DUF4235 | DUF4235 | Family | 3,560 | false | false | This family of integral membrane proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14019"
] | [
"DUF4235"
] | [
3560
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
3526,
34
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4235 | Protein of unknown function DUF4235 | DUF4235 | 5 |
IPR025330 | 25,330 | Domain of unknown function DUF4236 | DUF4236 | Domain | 2,828 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14020"
] | [
"DUF4236"
] | [
2828
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Iainarchaeum sp.",
"Caudoviricetes",
"metagenomes"
] | [
2769,
1,
28,
30
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4236 | Domain of unknown function DUF4236 | DUF4236 | 3 |
IPR025332 | 25,332 | Protein of unknown function DUF4238 | DUF4238 | Family | 3,613 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14022"
] | [
"DUF4238"
] | [
3613
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"Methanobacteriati",
"metagenomes"
] | [
2628,
2,
878,
52,
53
] | 5 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
2
] | 1 | true | Family | Protein of unknown function DUF4238 | Protein of unknown function DUF4238 | DUF4238 | 7 |
IPR025333 | 25,333 | Protein of unknown function DUF4239 | DUF4239 | Family | 5,846 | false | false | This family of proteins is functionally uncharacterised. It is distantly related to bestrophin proteins. Structure prediction suggests that these proteins can form homopentamers as Bestrophin proteins do. These proteins may function as chloride channels. This domain is sometimes found at the C terminus in large RHS pro... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14023"
] | [
"Bestrophin-like"
] | [
5846
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
5461,
311,
74
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4239 | Protein of unknown function DUF4239 | DUF4239 | 1 |
IPR025334 | 25,334 | Domain of unknown function DUF4240 | DUF4240 | Domain | 3,533 | false | false | The function of this domain is not known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14024"
] | [
"DUF4240"
] | [
3533
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"metagenomes"
] | [
3491,
15,
14,
13
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4240 | Domain of unknown function DUF4240 | DUF4240 | 5 |
IPR025335 | 25,335 | Protein of unknown function DUF4241 | DUF4241 | Family | 1,967 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14025"
] | [
"DUF4241"
] | [
1967
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriati",
"Viruses",
"metagenomes"
] | [
1933,
12,
3,
8,
11
] | 5 | [] | [] | 0 | true | Family | Protein of unknown function DUF4241 | Protein of unknown function DUF4241 | DUF4241 | 1 |
IPR025336 | 25,336 | SCO4226-like | SCO4226-like | Family | 3,670 | false | false | This entry represents a family of proteins found in prokaryotes, including SCO4226 from Streptomyces coelicolor ( ). This protein adopts a dimeric configuration able to bind four nickel ions, with each monomer showing a typical ferredoxin-like fold with five β-strands packing against two α-helices. It may play a role i... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14026"
] | [
"SCO4226-like"
] | [
3670
] | 1 | [] | [] | [] | 0 | [
"4oi3",
"4oi6"
] | 2 | [
"PUB00093075"
] | [
"25285530"
] | [
"Streptomyces coelicolor SCO4226 is a nickel binding protein."
] | [
2014
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
109,
3524,
13,
24
] | 4 | [] | [] | 0 | true | Family | SCO4226-like | SCO4226-like | SCO4226-like | 3 |
IPR025337 | 25,337 | Questin oxidase-like | Questin_oxidase-like | Family | 5,652 | false | false | This family consists of oxidoreductases involved in the synthesis of different polyketides and derivatives. Questin oxidase GedK from Aspergillus terreus catalyses the ring cleavage of the anthraquinone questin to form benzophenone desmethylsulochrin [ ]. It is part of the gene cluster that mediates the biosynthesis of... | [
"GO:0016491"
] | [
"oxidoreductase activity"
] | [
"molecular_function"
] | 1 | [
"PFAM",
"PANTHER"
] | [
"PF14027",
"PTHR35870"
] | [
"Questin_oxidase",
""
] | [
5647,
4942
] | 2 | [] | [] | [] | 0 | [
"7y3w",
"7y3x",
"7y3y",
"8yxs",
"8z4q",
"8z4r",
"8z4s"
] | 7 | [
"PUB00081405",
"PUB00083132",
"PUB00086982",
"PUB00086983",
"PUB00088179",
"PUB00088181",
"PUB00088717",
"PUB00093703",
"PUB00093718",
"PUB00093719",
"PUB00093720"
] | [
"24009710",
"15006741",
"3182756",
"20139316",
"24302702",
"15094053",
"28955461",
"20722388",
"26278536",
"26242966",
"30746079"
] | [
"Heterologous reconstitution of the intact geodin gene cluster in Aspergillus nidulans through a simple and versatile PCR based approach.",
"Clustered pathway genes in aflatoxin biosynthesis.",
"A novel anthraquinone ring cleavage enzyme from Aspergillus terreus.",
"Characterization of the Aspergillus nidulan... | [
2013,
2004,
1988,
2010,
2014,
2004,
2016,
2010,
2015,
2016,
2019
] | 11 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
1026,
4626
] | 2 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
2
] | 1 | true | Family | Questin oxidase-like | Questin oxidase-like | Questin_oxidase-like | 4 |
IPR025338 | 25,338 | Protein of unknown function DUF4244 | DUF4244 | Family | 4,436 | false | false | This family of proteins is functionally uncharacterised. There is a conserved EYA sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14029"
] | [
"DUF4244"
] | [
4436
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Pleodorina starrii",
"metagenomes"
] | [
4372,
1,
63
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4244 | Protein of unknown function DUF4244 | DUF4244 | 9 |
IPR025342 | 25,342 | Protein of unknown function DUF4248 | DUF4248 | Family | 1,371 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14053"
] | [
"DUF4248"
] | [
1371
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Siphoviridae sp. ctPAi1",
"unclassified sequences"
] | [
1342,
1,
28
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4248 | Protein of unknown function DUF4248 | DUF4248 | 4 |
IPR025344 | 25,344 | Plastid division protein CDP1-like, IMS domain | CDP1-like_IMS | Domain | 1,892 | false | false | This domain corresponds to the C-terminal intermembrane space (IMS) region from Plastid division protein CDP1, Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6 (ARC6) and its paralogue PARC6 [ ]. This group of proteins function as key components of the plastid division machinery, which is responsible for the cons... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13355"
] | [
"ARC6-like_IMS"
] | [
1892
] | 1 | [] | [] | [] | 0 | [
"5d9r",
"5gtb",
"5had",
"5u9l",
"5u9o",
"6jzf",
"6jzn"
] | 7 | [
"PUB00096837",
"PUB00096838",
"PUB00096839",
"PUB00096840",
"PUB00160083",
"PUB00160085"
] | [
"18812496",
"26452626",
"26527658",
"32010156",
"23936263",
"28984364"
] | [
"Arabidopsis ARC6 coordinates the division machineries of the inner and outer chloroplast membranes through interaction with PDV2 in the intermembrane space.",
"Crystal structure of a conserved domain in the intermembrane space region of the plastid division protein ARC6.",
"Roles of Arabidopsis PARC6 in Coordi... | [
2008,
2016,
2016,
2019,
2013,
2018
] | 6 | [] | [] | 0 | 0 | null | [
"Bacillati",
"Eukaryota"
] | [
542,
1350
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
10,
6,
8
] | 3 | true | Domain | Plastid division protein CDP1-like, IMS domain | Plastid division protein CDP1-like, IMS domain | CDP1-like_IMS | 9 |
IPR025345 | 25,345 | Protein of unknown function DUF4249 | DUF4249 | Family | 6,221 | false | false | This family of proteins is functionally uncharacterised. There are two completely conserved residues (C and G) that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14054"
] | [
"DUF4249"
] | [
6221
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Potamilus streckersoni",
"metagenomes"
] | [
6127,
1,
93
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4249 | Protein of unknown function DUF4249 | DUF4249 | 8 |
IPR025347 | 25,347 | Protein of unknown function DUF4251 | DUF4251 | Family | 1,876 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14059"
] | [
"DUF4251"
] | [
1876
] | 1 | [] | [] | [] | 0 | [
"3fyf",
"4gdz"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteroidota",
"metagenomes"
] | [
1857,
19
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4251 | Protein of unknown function DUF4251 | DUF4251 | 5 |
IPR025348 | 25,348 | Protein of unknown function DUF4252 | DUF4252 | Family | 3,578 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14060"
] | [
"DUF4252"
] | [
3578
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
3533,
3,
42
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4252 | Protein of unknown function DUF4252 | DUF4252 | 4 |
IPR025349 | 25,349 | Domain of unknown function DUF4253 | DUF4253 | Domain | 2,126 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14062"
] | [
"DUF4253"
] | [
2126
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
2123,
3
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4253 | Domain of unknown function DUF4253 | DUF4253 | 8 |
IPR025350 | 25,350 | Protein of unknown function DUF4254 | DUF4254 | Family | 2,863 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14063"
] | [
"DUF4254"
] | [
2863
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Ricinus communis",
"metagenomes"
] | [
2816,
1,
46
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4254 | Protein of unknown function DUF4254 | DUF4254 | 7 |
IPR025352 | 25,352 | Protein of unknown function DUF4256 | DUF4256 | Family | 2,595 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14066"
] | [
"DUF4256"
] | [
2595
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Rhabditomorpha",
"bioreactor metagenome"
] | [
13,
2558,
2,
22
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF4256 | Protein of unknown function DUF4256 | DUF4256 | 5 |
IPR025353 | 25,353 | Protein of unknown function DUF4257) | DUF4257 | Family | 359 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14074"
] | [
"DUF4257"
] | [
359
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
359
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF4257) | Protein of unknown function DUF4257) | DUF4257 | 1 |
IPR025354 | 25,354 | Protein of unknown function DUF4258 | DUF4258 | Family | 2,479 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14076"
] | [
"DUF4258"
] | [
2479
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
133,
2233,
31,
7,
75
] | 5 | [] | [] | 0 | true | Family | Protein of unknown function DUF4258 | Protein of unknown function DUF4258 | DUF4258 | 4 |
IPR025355 | 25,355 | Protein of unknown function DUF4259 | DUF4259 | Family | 2,006 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14078"
] | [
"DUF4259"
] | [
2006
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1969,
32,
5
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4259 | Protein of unknown function DUF4259 | DUF4259 | 1 |
IPR025356 | 25,356 | Protein of unknown function DUF4260 | DUF4260 | Family | 2,383 | false | false | This family of integral membrane proteins is functionally uncharacterised. There is a conserved GLK sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14079"
] | [
"DUF4260"
] | [
2383
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halobacteriales",
"ecological metagenomes"
] | [
2289,
47,
42,
5
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF4260 | Protein of unknown function DUF4260 | DUF4260 | 4 |
IPR025358 | 25,358 | Protein of unknown function DUF4262 | DUF4262 | Family | 2,106 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14081"
] | [
"DUF4262"
] | [
2106
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"ecological metagenomes"
] | [
2069,
8,
6,
23
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF4262 | Protein of unknown function DUF4262 | DUF4262 | 4 |
IPR025359 | 25,359 | Shedu protein SduA, C-terminal | SduA_C | Domain | 1,803 | false | false | This entry represents the C-terminal domain of SduA, the only component of antiviral defense system Shedu. Expression of Shedu in B.subtilis (strain BEST7003) confers resistance to phages phi105, phi29, rho14 and to a lesser extent to SPP1 [ ]. This domain may have endonuclease activity. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14082"
] | [
"SduA_C"
] | [
1803
] | 1 | [] | [] | [] | 0 | [
"8ps4",
"8ps5",
"8ti8",
"8ti9",
"8tia"
] | 5 | [
"PUB00097806"
] | [
"29371424"
] | [
"Systematic discovery of antiphage defense systems in the microbial pangenome."
] | [
2018
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Enterobacteria phage P2-EC31",
"Eukaryota",
"metagenomes"
] | [
20,
1759,
1,
3,
20
] | 5 | [] | [] | 0 | true | Domain | Shedu protein SduA, C-terminal | Shedu protein SduA, C-terminal | SduA_C | 9 |
IPR025361 | 25,361 | Protein of unknown function DUF4265 | DUF4265 | Family | 1,577 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14085"
] | [
"DUF4265"
] | [
1577
] | 1 | [] | [] | [] | 0 | [
"5ueb"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halorubrum tibetense",
"ecological metagenomes",
"uncultured Caudovirales phage"
] | [
1566,
3,
1,
6,
1
] | 5 | [] | [] | 0 | true | Family | Protein of unknown function DUF4265 | Protein of unknown function DUF4265 | DUF4265 | 3 |
IPR025362 | 25,362 | Domain of unknown function DUF4266 | DUF4266 | Domain | 1,725 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14086"
] | [
"DUF4266"
] | [
1725
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Tanacetum cinerariifolium",
"ecological metagenomes"
] | [
1677,
1,
47
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4266 | Domain of unknown function DUF4266 | DUF4266 | 6 |
IPR025363 | 25,363 | Protein of unknown function DUF4267 | DUF4267 | Family | 4,316 | false | false | This family of putative integral membrane proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14087"
] | [
"DUF4267"
] | [
4316
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1870,
2444,
2
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4267 | Protein of unknown function DUF4267 | DUF4267 | 6 |
IPR025364 | 25,364 | Domain of unknown function DUF4268 | DUF4268 | Domain | 2,722 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14088"
] | [
"DUF4268"
] | [
2722
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"Viruses",
"unclassified sequences"
] | [
2582,
5,
88,
5,
42
] | 5 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4268 | Domain of unknown function DUF4268 | DUF4268 | 3 |
IPR025365 | 25,365 | Protein of unknown function DUF4269 | DUF4269 | Family | 1,322 | false | false | This family of proteins is functionally uncharacterised. There is a conserved KTE sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14091"
] | [
"DUF4269"
] | [
1322
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1314,
5,
3
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4269 | Protein of unknown function DUF4269 | DUF4269 | 5 |
IPR025366 | 25,366 | Protein of unknown function DUF4270 | DUF4270 | Family | 3,111 | false | false | This family of putative lipoproteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14092"
] | [
"DUF4270"
] | [
3111
] | 1 | [] | [] | [] | 0 | [
"9his",
"9hj3",
"9n2d"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadati",
"metagenomes"
] | [
4,
3057,
50
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4270 | Protein of unknown function DUF4270 | DUF4270 | 4 |
IPR025367 | 25,367 | Protein of unknown function DUF4271 | DUF4271 | Family | 2,467 | false | false | This family of putative integral membrane proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14093"
] | [
"DUF4271"
] | [
2467
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Siphoviridae sp. ctBLh2",
"metagenomes"
] | [
2423,
1,
43
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4271 | Protein of unknown function DUF4271 | DUF4271 | 5 |
IPR025369 | 25,369 | Domain of unknown function DUF4274 | DUF4274 | Domain | 667 | false | false | This presumed domain is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14096"
] | [
"DUF4274"
] | [
667
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
667
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4274 | Domain of unknown function DUF4274 | DUF4274 | 6 |
IPR025370 | 25,370 | Transcriptional regulator SgrR, N-terminal HTH domain | SgrR_HTH_N | Domain | 6,427 | false | false | Small, non-coding RNA molecules play important regulatory roles in a variety of physiological processes in bacteria. This entry represents the N-terminal domain of the SgrR family of proteins which regulate the transcription of these sRNAs, in particular SgrS. This domain contains a helix-turn-helix motif characteristi... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF12793"
] | [
"SgrR_N"
] | [
6427
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00057334",
"PUB00057335"
] | [
"15522088",
"17209026"
] | [
"Involvement of a novel transcriptional activator and small RNA in post-transcriptional regulation of the glucose phosphoenolpyruvate phosphotransferase system.",
"The novel transcription factor SgrR coordinates the response to glucose-phosphate stress."
] | [
2004,
2007
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"human gut metagenome"
] | [
6423,
3,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Domain | Transcriptional regulator SgrR, N-terminal HTH domain | Transcriptional regulator SgrR, N-terminal HTH domain | SgrR_HTH_N | 9 |
IPR025371 | 25,371 | BT_3044-like, C-terminal | BT_3044-like_C | Domain | 770 | false | false | This entry represents a domain found at the C-terminal end of a group of proteins from bacteroidetes. Some members of this group also contain , including BT_3044 from Bacteroides thetaiotaomicron ( ), a glycan binding enzyme that could degrade oligosaccharides or even large molecular size glycans [ ]. Many other member... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14274"
] | [
"BT_3044-like_C"
] | [
770
] | 1 | [] | [] | [] | 0 | [
"3nqk",
"3p02",
"3sot",
"4qni"
] | 4 | [
"PUB00152802"
] | [
"34420703"
] | [
"Discrete genetic loci in human gut Bacteroides thetaiotaomicron confer pectin metabolism."
] | [
2021
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteroidota",
"Wickerhamomyces ciferrii (strain ATCC 14091 / BCRC 22168 / CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031 F-60-10)",
"metagenomes"
] | [
751,
1,
18
] | 3 | [] | [] | 0 | true | Domain | BT_3044-like, C-terminal | BT_3044-like, C-terminal | BT_3044-like_C | 2 |
IPR025372 | 25,372 | Protein of unknown function DUF4362 | DUF4362 | Family | 736 | false | false | This family of proteins mainly found in firmicutes is functionally uncharacterised. There is a conserved IRIV sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14275"
] | [
"DUF4362"
] | [
736
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanimicrococcus hacksteinii",
"bioreactor metagenome"
] | [
732,
1,
3
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF4362 | Protein of unknown function DUF4362 | DUF4362 | 6 |
IPR025373 | 25,373 | Protein of unknown function DUF4363 | DUF4363 | Family | 915 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14276"
] | [
"DUF4363"
] | [
915
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati",
"ecological metagenomes"
] | [
896,
19
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4363 | Protein of unknown function DUF4363 | DUF4363 | 4 |
IPR025374 | 25,374 | Protein of unknown function DUF4364 | DUF4364 | Family | 1,164 | false | false | This family of proteins is functionally uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14277"
] | [
"DUF4364"
] | [
1164
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
1137,
27
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4364 | Protein of unknown function DUF4364 | DUF4364 | 6 |
IPR025375 | 25,375 | Domain of unknown function DUF4365 | DUF4365 | Domain | 3,137 | false | false | The function of this domain is not known. There is a single completely conserved residue D that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14280"
] | [
"DUF4365"
] | [
3137
] | 1 | [] | [] | [] | 0 | [
"9jsb",
"9jsp",
"9jsz",
"9jt2"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Leptospira phage LE1",
"ecological metagenomes"
] | [
28,
3090,
6,
1,
12
] | 5 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4365 | Domain of unknown function DUF4365 | DUF4365 | 9 |
IPR025376 | 25,376 | Mobile element protein CD1107-like domain | CD1107-like_dom | Domain | 1,894 | false | false | This domain is found in the mobile element protein CD1107 from Clostridioides difficile ( , ) and similar proteins mainly found in firmicutes. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14283"
] | [
"CD1107-like"
] | [
1894
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00154582"
] | [
"21876735"
] | [
"Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile."
] | [
2011
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanolapillus africanus",
"Sciurus vulgaris",
"Siphoviridae sp. ctoWO12",
"unclassified sequences"
] | [
1858,
1,
1,
1,
33
] | 5 | [] | [] | 0 | true | Domain | Mobile element protein CD1107-like domain | Mobile element protein CD1107-like domain | CD1107-like_dom | 1 |
IPR025377 | 25,377 | Domain of unknown function DUF4367 | DUF4367 | Domain | 2,343 | false | false | The function of this domain is not known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14285"
] | [
"DUF4367"
] | [
2343
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Siphoviridae sp. ctb1k4",
"unclassified sequences"
] | [
188,
2118,
1,
36
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4367 | Domain of unknown function DUF4367 | DUF4367 | 5 |
IPR025378 | 25,378 | Domain of unknown function DUF4368 | DUF4368 | Domain | 4,127 | false | false | The function of this domain is not known. There is a single completely conserved residue G that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14287"
] | [
"DUF4368"
] | [
4127
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"unclassified Caudoviricetes",
"unclassified sequences"
] | [
4058,
2,
67
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4368 | Domain of unknown function DUF4368 | DUF4368 | 8 |
IPR025379 | 25,379 | Protein of unknown function DUF4295 | DUF4295 | Family | 2,203 | false | false | This family of functionally uncharacterised proteins is found in bacteria. Proteins in this family are approximately 50 amino acids in length. There are two completely conserved residues (K and Y) that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14128"
] | [
"DUF4295"
] | [
2203
] | 1 | [] | [] | [] | 0 | [
"7jil",
"9i5t",
"9i5v"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"metagenomes"
] | [
2153,
50
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4295 | Protein of unknown function DUF4295 | DUF4295 | 3 |
IPR025380 | 25,380 | Domain of unknown function DUF4369 | DUF4369 | Domain | 9,030 | false | false | The function of this domain is not known. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14289"
] | [
"DUF4369"
] | [
9030
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
8890,
5,
135
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF4369 | Domain of unknown function DUF4369 | DUF4369 | 5 |
IPR025382 | 25,382 | CD-NTase associated protein 4-like, DNA endonuclease domain | Cap4-like_endonuclease_dom | Domain | 962 | false | false | This entry corresponds to the N-terminal domain found in CD-NTase associated protein 4 (Cap4) from Enterobacter cloacae. This is the effector domain which has dsDNA nuclease activity, sharing structural homology with type II restriction endonucleases and it has the putative active-site conserved residues required for d... | [
"GO:0004518"
] | [
"nuclease activity"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF14130"
] | [
"Cap4_nuclease"
] | [
962
] | 1 | [] | [] | [] | 0 | [
"6vm5",
"6vm6",
"6wam",
"6wan",
"8zue"
] | 5 | [
"PUB00094500"
] | [
"32544385"
] | [
"CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection."
] | [
2020
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Capitella teleta",
"Methanobacteriota",
"metagenomes"
] | [
947,
1,
8,
6
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Domain | CD-NTase associated protein 4-like, DNA endonuclease domain | CD-NTase associated protein 4-like, DNA endonuclease domain | Cap4-like_endonuclease_dom | 5 |
IPR025383 | 25,383 | MrpA C-terminal/MbhD | MrpA_C/MbhD | Domain | 14,293 | false | false | Hydrogen gas-evolving membrane-bound hydrogenase (MBH) is a respiratory complex homologous to the quinone-reducing Complex I which share a common ancestor, the Mrp antiporter [ , ]. Like Complex I, MBH has peripheral and membrane arms. MBH is made of 14 subunits (MbhA-N). MbhJ, K, L, N and M form the Membrane-anchored ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13244"
] | [
"MbhD"
] | [
14293
] | 1 | [] | [] | [] | 0 | [
"6cfw",
"6u8y",
"6z16",
"7d3u",
"7qru"
] | 5 | [
"PUB00098952",
"PUB00098954",
"PUB00098955"
] | [
"29754813",
"32735215",
"33229520"
] | [
"Structure of an Ancient Respiratory System.",
"Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter.",
"Structure of the <i>Dietzia</i> Mrp complex reveals molecular mechanism of this giant bacterial sodium proton pump."
] | [
2018,
2020,
2020
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
846,
13271,
16,
160
] | 4 | [] | [] | 0 | true | Domain | MrpA C-terminal/MbhD | MrpA C-terminal/MbhD | MrpA_C/MbhD | 1 |
IPR025384 | 25,384 | Protein of unknown function DUF4298 | DUF4298 | Family | 838 | false | false | This family of bacterial proteins includes sHIP ( ) from Streptococcus pyogenes. This protein is though to play an important role in the virulence of the bacteria. This protein shows a unique tetrameric organisation composed of four helix-loop-helix motifs [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14131"
] | [
"DUF4298"
] | [
838
] | 1 | [] | [] | [] | 0 | [
"4mer",
"4pz1"
] | 2 | [
"PUB00101005"
] | [
"24825900"
] | [
"Functional and structural properties of a novel protein and virulence factor (Protein sHIP) in Streptococcus pyogenes."
] | [
2014
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Fungi",
"Myoviridae sp. ctLjW1",
"gut metagenome"
] | [
829,
7,
1,
1
] | 4 | [] | [] | 0 | true | Family | Protein of unknown function DUF4298 | Protein of unknown function DUF4298 | DUF4298 | 7 |
IPR025385 | 25,385 | Domain of unknown function DUF4092 | DUF4092 | Domain | 355 | false | false | This presumed domain is functionally uncharacterised. It is found in accessory colonisation factor AcfD [ ] and uncharacterised proteins from Proteobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13322"
] | [
"DUF4092"
] | [
355
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00057397"
] | [
"1644747"
] | [
"Structural analysis of the acfA and acfD genes of Vibrio cholerae: effects of DNA topology and transcriptional activators on expression."
] | [
1992
] | 1 | [] | [] | 0 | 0 | null | [
"Oryza sativa subsp. indica",
"Pseudomonadati",
"ecological metagenomes"
] | [
1,
352,
2
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF4092 | Domain of unknown function DUF4092 | DUF4092 | 4 |
IPR025387 | 25,387 | Protein of unknown function DUF4299 | DUF4299 | Family | 596 | false | false | This family is functionally uncharacterised. It contains two conserved sequence motifs (RGF and DAY), and two completely conserved residues (P and D) that may be functionally important. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14132"
] | [
"DUF4299"
] | [
596
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
594,
2
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF4299 | Protein of unknown function DUF4299 | DUF4299 | 3 |
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