interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR051139 | 51,139 | Mediator complex subunit 13 | Mediator_complx_sub13 | Family | 7,695 | true | false | The Mediator complex subunit 13 family consists of proteins that are integral components of the Mediator complex, a key coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Members of the family function as a bridge to convey information from gene-specific regulatory prot... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR48249"
] | [
"Mediator_complx_sub13"
] | [
7695
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DME-9841922",
"R-HSA-1989781",
"R-HSA-212436",
"R-HSA-381340",
"R-HSA-9833110",
"R-HSA-9841922"
] | [
"REACTOME:R-DME-9841922",
"REACTOME:R-HSA-1989781",
"REACTOME:R-HSA-212436",
"REACTOME:R-HSA-381340",
"REACTOME:R-HSA-9833110",
"REACTOME:R-HSA-9841922"
] | 6 | [
"7kpv",
"7kpx",
"8t1l",
"8t9d",
"8tq2",
"8tqc",
"8tqw",
"8trh"
] | 8 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
7695
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
6,
1,
3,
4,
11,
7,
1,
5,
8,
1,
1,
34
] | 12 | true | Family | Mediator complex subunit 13 | Mediator complex subunit 13 | Mediator_complx_sub13 | 4 |
IPR051141 | 51,141 | UPF0339 domain-containing protein | UPF0339_domain | Family | 4,268 | true | false | This family of proteins is characterized by the UPF0339 domain. The precise biological functions of these proteins are not well-defined. However, proteins with the UPF0339 domain are often found in various bacterial species and may play a role in cellular processes. The domain's presence across different organisms sugg... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR40606"
] | [
"UPF0339_domain"
] | [
4268
] | 1 | [] | [] | [] | 0 | [
"2k49",
"2k7i",
"2k8e"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriati",
"unclassified sequences"
] | [
3925,
4,
289,
50
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | UPF0339 domain-containing protein | UPF0339 domain-containing protein | UPF0339_domain | 3 |
IPR051142 | 51,142 | Glycosyltransferase 29 | Glycosyltransferase_29 | Family | 6,502 | true | false | The glycosyltransferase 29 family is responsible for the sialylation of glycoproteins and glycolipids, a process critical for various biological functions. Members of this family transfer sialic acid to terminal carbohydrate groups, forming specific sequences that are essential in cell-cell recognition, signaling, and ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR13713"
] | [
"Glycosyltransferase_29"
] | [
6502
] | 1 | [
"EC",
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",... | [
"2.4.3",
"2.4.3.6",
"PWY-7426",
"PWY-7434",
"PWY-7831",
"PWY-7833",
"PWY-7841",
"R-BTA-2022854",
"R-BTA-4085001",
"R-BTA-9037629",
"R-HSA-1912420",
"R-HSA-2022854",
"R-HSA-3656243",
"R-HSA-4085001",
"R-HSA-9037629",
"R-HSA-9683673",
"R-HSA-9694548",
"R-HSA-9694719",
"R-HSA-975577... | [
"EC:2.4.3",
"EC:2.4.3.6",
"METACYC:PWY-7426",
"METACYC:PWY-7434",
"METACYC:PWY-7831",
"METACYC:PWY-7833",
"METACYC:PWY-7841",
"REACTOME:R-BTA-2022854",
"REACTOME:R-BTA-4085001",
"REACTOME:R-BTA-9037629",
"REACTOME:R-HSA-1912420",
"REACTOME:R-HSA-2022854",
"REACTOME:R-HSA-3656243",
"REACTOM... | 33 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Marine Group I thaumarchaeote",
"Viruses"
] | [
11,
6475,
1,
15
] | 4 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
41,
70,
20,
21
] | 4 | true | Family | Glycosyltransferase 29 | Glycosyltransferase 29 | Glycosyltransferase_29 | 7 |
IPR051143 | 51,143 | TrkH Potassium Transport | TrkH_K-transport | Family | 6,840 | true | false | The TrkH potassium transport family is involved in the regulation of potassium-sodium homeostasis and the maintenance of the proper sodium/potassium ratio in cells. Members of this family function primarily as potassium transporters, with some also mediating sodium transport. They are characterized by having pore-formi... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR31064"
] | [
"TrkH_K-transport"
] | [
6840
] | 1 | [] | [] | [] | 0 | [
"8k66",
"8k69",
"8w9n",
"8w9o",
"8w9t",
"8w9v",
"8y6j",
"8y6l",
"8y6m",
"8y6n"
] | 10 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Borrelia duttonii CR2A",
"Eukaryota"
] | [
1,
6839
] | 2 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
12,
2,
19,
2,
2,
9
] | 6 | true | Family | TrkH Potassium Transport | TrkH Potassium Transport | TrkH_K-transport | 3 |
IPR051144 | 51,144 | Formin homology domain-containing protein | Formin_homology_domain | Family | 6,294 | true | false | This family of proteins is involved in the regulation of actin cytoskeleton dynamics. Members of this family are known to nucleate the formation of linear actin filaments, which are essential for various cellular processes including cell shape determination, cell division, and cell signaling. The proteins typically con... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR45733"
] | [
"Formin_homology_domain"
] | [
6294
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanoculleus methanifontis",
"Viruses",
"viral metagenome"
] | [
143,
6136,
1,
11,
3
] | 5 | [
"Arabidopsis thaliana",
"Drosophila melanogaster",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
68,
2,
29,
65
] | 4 | true | Family | Formin homology domain-containing protein | Formin homology domain-containing protein | Formin_homology_domain | 3 |
IPR051145 | 51,145 | Growth Arrest-Specific/Sex Hormone-Binding/Vitamin K-Dependent | GAS-SHBG-PROS | Family | 4,588 | true | false | The protein family includes proteins involved in various biological processes such as cell growth and survival, cell adhesion, cell migration, anticoagulation, steroid hormone regulation, and TGF-beta activation control. Members act as ligands for receptor tyrosine kinases, transport androgens, serve as cofactors in co... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR24040"
] | [
"GAS-SHBG-PROS"
] | [
4588
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-114608",
"R-BTA-140837",
"R-BTA-140875",
"R-BTA-159740",
"R-BTA-159763",
"R-BTA-159782",
"R-BTA-202733",
"R-HSA-114608",
"R-HSA-140837",
"R-HSA-140875",
"R-HSA-159740",
"R-HSA-159763",
"R-HSA-159782",
"R-HSA-202733",
"R-HSA-381426",
"R-HSA-8957275",
"R-HSA-977606",
"R-MMU-11... | [
"REACTOME:R-BTA-114608",
"REACTOME:R-BTA-140837",
"REACTOME:R-BTA-140875",
"REACTOME:R-BTA-159740",
"REACTOME:R-BTA-159763",
"REACTOME:R-BTA-159782",
"REACTOME:R-BTA-202733",
"REACTOME:R-HSA-114608",
"REACTOME:R-HSA-140837",
"REACTOME:R-HSA-140875",
"REACTOME:R-HSA-159740",
"REACTOME:R-HSA-159... | 35 | [
"1d2s",
"1f5f",
"1h30",
"1hj7",
"1hz8",
"1i0u",
"1kdk",
"1kdm",
"1lhn",
"1lho",
"1lhu",
"1lhv",
"1lhw",
"1lmj",
"1z6c",
"2c5d",
"2m74",
"2w2m",
"2w2n",
"2w2o",
"2w2p",
"2w2q",
"3bps",
"3gcw",
"3gcx",
"4ra0",
"5ms9",
"5vxz",
"6pya",
"6pyb",
"6pyf",
"6ulb"... | 32 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
3,
4585
] | 2 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
7,
48,
7,
25
] | 4 | true | Family | Growth Arrest-Specific/Sex Hormone-Binding/Vitamin K-Dependent | Growth Arrest-Specific/Sex Hormone-Binding/Vitamin K-Dependent | GAS-SHBG-PROS | 9 |
IPR051147 | 51,147 | Cilia- and flagella-associated domain-containing protein | CFAP_domain-containing | Family | 5,479 | true | false | This family of proteins is involved in the structure and function of cilia and flagella, which are cellular appendages that play a critical role in cell motility, fluid movement, and sensory functions. Members of this family are associated with the axoneme, the core skeletal structure of cilia and flagella, and are imp... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR21683"
] | [
"CFAP_domain-containing"
] | [
5479
] | 1 | [] | [] | [] | 0 | [
"8glv",
"8j07",
"9e5c",
"9fqr"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
5479
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
13,
3,
8,
7,
19
] | 5 | true | Family | Cilia- and flagella-associated domain-containing protein | Cilia- and flagella-associated domain-containing protein | CFAP_domain-containing | 9 |
IPR051148 | 51,148 | Zona Pellucida Domain Glycoprotein | Zona_Pellucida_Domain_gp | Family | 4,492 | true | false | The Zona Pellucida Domain (ZPD) family includes glycoproteins that are essential components of the zona pellucida, an extracellular matrix that surrounds oocytes. The ZPD family mediates critical reproductive processes such as sperm binding, induction of the acrosome reaction, and prevention of post-fertilization polys... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR23343"
] | [
"Zona_Pellucida_Domain_gp"
] | [
4492
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-2534343",
"R-HSA-2534343",
"R-MMU-2534343",
"R-SSC-2534343"
] | [
"REACTOME:R-BTA-2534343",
"REACTOME:R-HSA-2534343",
"REACTOME:R-MMU-2534343",
"REACTOME:R-SSC-2534343"
] | 4 | [
"5bup",
"6gf6",
"6gf7",
"6gf8",
"8bqu",
"8rke",
"8rkf",
"8rkh",
"8rki"
] | 9 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eumetazoa"
] | [
4492
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
11,
6,
8,
16
] | 4 | true | Family | Zona Pellucida Domain Glycoprotein | Zona Pellucida Domain Glycoprotein | Zona_Pellucida_Domain_gp | 8 |
IPR051149 | 51,149 | Spindly/BICDR Dynein Motor Adapter | Spindly/BICDR_Dynein_Adapter | Family | 4,404 | true | true | The Spindly/BICDR protein family is involved in the regulation of dynein motor activity and cargo transport [ , , ]. Spindly proteins are essential for the localisation of dynein and dynactin to the mitotic kinetochore, controlling the interaction between the kinetochore and spindle microtubules and facilitating the fo... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR32123"
] | [
"Spindly/BICDR_Dynein_Adapter"
] | [
4404
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-HSA-141444",
"R-HSA-2467813",
"R-HSA-2500257",
"R-HSA-5663220",
"R-HSA-68877",
"R-HSA-9648025",
"R-MMU-141444",
"R-MMU-2467813",
"R-MMU-2500257",
"R-MMU-5663220",
"R-MMU-68877",
"R-MMU-9648025",
"R-RNO-141444",
"R-RNO-2467813",
"R-RNO-2500257",
"R-RNO-5663220",
"R-RNO-68877",
"R... | [
"REACTOME:R-HSA-141444",
"REACTOME:R-HSA-2467813",
"REACTOME:R-HSA-2500257",
"REACTOME:R-HSA-5663220",
"REACTOME:R-HSA-68877",
"REACTOME:R-HSA-9648025",
"REACTOME:R-MMU-141444",
"REACTOME:R-MMU-2467813",
"REACTOME:R-MMU-2500257",
"REACTOME:R-MMU-5663220",
"REACTOME:R-MMU-68877",
"REACTOME:R-MM... | 24 | [
"6f1t",
"6f1u",
"6znm",
"7z8f",
"7z8i",
"7z8j",
"7z8k",
"7z8m",
"8arf",
"9dgt",
"9dgu"
] | 11 | [
"PUB00044111",
"PUB00068812",
"PUB00147713",
"PUB00156756",
"PUB00161831",
"PUB00161832"
] | [
"17576797",
"19468067",
"25035494",
"29420470",
"33734450",
"36071160"
] | [
"Spindly, a novel protein essential for silencing the spindle assembly checkpoint, recruits dynein to the kinetochore.",
"Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly.",
"Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes.",
"Cryo-EM show... | [
2007,
2009,
2014,
2018,
2021,
2022
] | 6 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halobacteriales"
] | [
3,
4399,
2
] | 3 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
16,
2,
16,
10,
16
] | 5 | true | Family | Spindly/BICDR Dynein Motor Adapter | Spindly/BICDR Dynein Motor Adapter | Spindly/BICDR_Dynein_Adapter | 1 |
IPR051151 | 51,151 | Group II amino acid decarboxylase | Group_II_decarboxylase | Family | 3,205 | true | true | This family of proteins includes enzymes that catalyze the decarboxylation of amino acids. Specifically, members of this family are involved in the biosynthesis of biogenic amines by removing a carboxyl group from their respective amino acid substrates. Some members are known to catalyze the formation of ethanolamine f... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR46101"
] | [
"Group_II_Decarboxylase"
] | [
3205
] | 1 | [
"EC",
"METACYC"
] | [
"4.1.1.22",
"PWY-6173"
] | [
"EC:4.1.1.22",
"METACYC:PWY-6173"
] | 2 | [
"7cif",
"7cig",
"7cii",
"7cij",
"7cim",
"7eru",
"7erv",
"8jg7",
"8jij",
"8jik"
] | 10 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Fervidicoccus fontis",
"Megaviricetes",
"unclassified sequences"
] | [
1344,
1838,
2,
9,
12
] | 5 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
2,
9,
9
] | 3 | true | Family | Group II amino acid decarboxylase | Group II amino acid decarboxylase | Group_II_decarboxylase | 8 |
IPR051152 | 51,152 | Caenorhabditis elegans Orphan Nuclear Receptors | C.elegans_Orphan_NR | Family | 1,720 | true | false | The nuclear hormone receptor family in Caenorhabditis elegans consists of proteins that are classified as orphan nuclear receptors. These proteins share a common structural similarity indicative of their membership in the nuclear hormone receptor superfamily. However, their specific biological functions remain largely ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR45680"
] | [
"C.elegans_Orphan_NR"
] | [
1720
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Protostomia"
] | [
1720
] | 1 | [
"Caenorhabditis elegans"
] | [
111
] | 1 | true | Family | Caenorhabditis elegans Orphan Nuclear Receptors | Caenorhabditis elegans Orphan Nuclear Receptors | C.elegans_Orphan_NR | 1 |
IPR051154 | 51,154 | Prespore-cell-inducing factor | Prespore-cell_inducing_factor | Family | 700 | true | false | The prespore-cell-inducing factor family comprises proteins that play a role in the development and differentiation of the social amoeba Dictyostelium discoideum. Members of the family are involved in quorum sensing and the regulation of gene expression in response to cell density. Specifically, they can induce the exp... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR31137"
] | [
"Prespore-cell_inducing_factor"
] | [
700
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Nitrososphaerota",
"metagenomes"
] | [
491,
203,
4,
2
] | 4 | [] | [] | 0 | true | Family | Prespore-cell-inducing factor | Prespore-cell-inducing factor | Prespore-cell_inducing_factor | 4 |
IPR051155 | 51,155 | Nematode Major Sperm | Nematode_MSP | Family | 1,271 | true | false | The Major Sperm Protein (MSP) family is essential for the motility of sperm cells in nematodes. Members of the MSP family are key components in the molecular mechanisms that facilitate sperm crawling. They achieve this by forming an extensive filament system, which is crucial for the dynamic structure of the sperm cell... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR22920"
] | [
"Nematode_MSP"
] | [
1271
] | 1 | [] | [] | [] | 0 | [
"1grw",
"1msp",
"2bvu",
"2msp",
"3msp"
] | 5 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Nematoda"
] | [
1271
] | 1 | [
"Caenorhabditis elegans"
] | [
24
] | 1 | true | Family | Nematode Major Sperm | Nematode Major Sperm | Nematode_MSP | 5 |
IPR051156 | 51,156 | Mitochondrial and Outer Membrane Metalloprotease | Mito/Outer_Membr_Metalloprot | Family | 36,147 | true | false | The protein family includes mitochondrial and outer membrane metalloproteases involved in quality control and stress response. Mitochondrial members act as part of the inner membrane quality control system, cleaving mistranslated or misfolded proteins and regulating mitochondrial dynamics and apoptosis in response to s... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR22726"
] | [
"Mito/Outer_Membr_Metalloprot"
] | [
36147
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-169911",
"R-BTA-9840373",
"R-DRE-169911",
"R-DRE-9840373",
"R-HSA-169911",
"R-HSA-9837999",
"R-HSA-9840373",
"R-MMU-169911",
"R-MMU-9840373",
"R-RNO-169911",
"R-RNO-9840373",
"R-SCE-169911",
"R-SCE-9840373",
"R-SPO-169911",
"R-SPO-9840373"
] | [
"REACTOME:R-BTA-169911",
"REACTOME:R-BTA-9840373",
"REACTOME:R-DRE-169911",
"REACTOME:R-DRE-9840373",
"REACTOME:R-HSA-169911",
"REACTOME:R-HSA-9837999",
"REACTOME:R-HSA-9840373",
"REACTOME:R-MMU-169911",
"REACTOME:R-MMU-9840373",
"REACTOME:R-RNO-169911",
"REACTOME:R-RNO-9840373",
"REACTOME:R-S... | 15 | [
"3c37",
"6ait",
"6sar"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"unclassified sequences"
] | [
51,
30417,
3,
5247,
429
] | 5 | [
"Arabidopsis thaliana",
"Danio rerio",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)... | [
6,
2,
3,
5,
1,
1,
4,
4,
1,
1,
8
] | 11 | true | Family | Mitochondrial and Outer Membrane Metalloprotease | Mitochondrial and Outer Membrane Metalloprotease | Mito/Outer_Membr_Metalloprot | 1 |
IPR051157 | 51,157 | Pyruvate Dehydrogenase/Transketolase | PDH/Transketolase | Family | 33,292 | true | false | The protein family includes components of the pyruvate dehydrogenase (PDH) complex, which are responsible for the conversion of pyruvate to acetyl-CoA and CO2, a critical step in cellular respiration. Some family members also exhibit reductase activity with pyruvate. Additionally, the family encompasses transketolase-r... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43825"
] | [
"PDH/Transketolase"
] | [
33292
] | 1 | [
"EC"
] | [
"1.2.4.1"
] | [
"EC:1.2.4.1"
] | 1 | [
"1l8a",
"1rp7",
"2g25",
"2g28",
"2g67",
"2iea",
"2qta",
"2qtc",
"3lpl",
"3lq2",
"3lq4",
"4qoy",
"6yaj",
"6yak"
] | 14 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
335,
31463,
571,
4,
919
] | 5 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Pyruvate Dehydrogenase/Transketolase | Pyruvate Dehydrogenase/Transketolase | PDH/Transketolase | 6 |
IPR051158 | 51,158 | Metallophosphoesterase-like | Metallophosphoesterase | Family | 31,781 | true | true | The metallophosphoesterase family encompasses enzymes that hydrolyze phosphoester bonds. Members of this family are involved in various biological processes, including the biosynthesis of lipid A, a component of the lipooligosaccharide that is essential for the structural integrity of the outer membrane in certain bact... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR31302"
] | [
"Metallophosphoesterase_sf"
] | [
31781
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
328,
29886,
1244,
2,
321
] | 5 | [
"Caenorhabditis elegans",
"Danio rerio",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
1,
1,
1,
1,
1
] | 6 | true | Family | Metallophosphoesterase-like | Metallophosphoesterase-like | Metallophosphoesterase | 4 |
IPR051159 | 51,159 | Hexapeptide-repeat containing acetyltransferases | Hexapeptide_acetyltransf | Family | 36,015 | true | false | The protein family is characterized by a group of acetyltransferases that share a common feature of belonging to the transferase hexapeptide repeat family. Members of this family are involved in various biochemical processes, including the O-acetylation of Nod factors, capsular polymeric sialic acid, and sophorolipids,... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR23416"
] | [
"Hexapeptide_acetyltransf"
] | [
36015
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"... | [
"2.3.1.-",
"PWY-3602",
"PWY-361",
"PWY-4801",
"PWY-4922",
"PWY-5048",
"PWY-5139",
"PWY-5268",
"PWY-5284",
"PWY-5292",
"PWY-5307",
"PWY-5313",
"PWY-5317",
"PWY-5318",
"PWY-5353",
"PWY-5400",
"PWY-5473",
"PWY-5475",
"PWY-5477",
"PWY-5660",
"PWY-5679",
"PWY-5710",
"PWY-5794"... | [
"EC:2.3.1.-",
"METACYC:PWY-3602",
"METACYC:PWY-361",
"METACYC:PWY-4801",
"METACYC:PWY-4922",
"METACYC:PWY-5048",
"METACYC:PWY-5139",
"METACYC:PWY-5268",
"METACYC:PWY-5284",
"METACYC:PWY-5292",
"METACYC:PWY-5307",
"METACYC:PWY-5313",
"METACYC:PWY-5317",
"METACYC:PWY-5318",
"METACYC:PWY-53... | 219 | [
"2ic7",
"2p2o",
"2wlc",
"2wld",
"2wle",
"2wlf",
"2wlg",
"3ect",
"3hjj",
"3igj",
"3jqy",
"3nz2",
"6ag8"
] | 13 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
824,
30523,
4316,
14,
338
] | 5 | [
"Escherichia coli (strain K12)",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
3,
3,
1
] | 3 | true | Family | Hexapeptide-repeat containing acetyltransferases | Hexapeptide-repeat containing acetyltransferases | Hexapeptide_acetyltransf | 3 |
IPR051163 | 51,163 | Sodium:Solute Symporter (SSF) | Sodium:Solute_Symporter_SSF | Family | 24,781 | true | false | The Sodium:Solute Symporter (SSF) family is involved in the electrogenic transport of various substrates across cell membranes, utilizing a sodium gradient as the driving force. Members of this family transport a diverse range of molecules, including multivitamins (biotin, pantothenate), monocarboxylates (lactate, pyru... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR42985"
] | [
"Sodium:Solute_Symporter_SSF"
] | [
24781
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-427601",
"R-DME-209968",
"R-DME-427601",
"R-DME-428643",
"R-DRE-196807",
"R-DRE-427601",
"R-DRE-428643",
"R-HSA-196780",
"R-HSA-196807",
"R-HSA-199220",
"R-HSA-209968",
"R-HSA-425397",
"R-HSA-427601",
"R-HSA-428643",
"R-HSA-5619096",
"R-MMU-196780",
"R-MMU-196807",
"R-MMU-19... | [
"REACTOME:R-BTA-427601",
"REACTOME:R-DME-209968",
"REACTOME:R-DME-427601",
"REACTOME:R-DME-428643",
"REACTOME:R-DRE-196807",
"REACTOME:R-DRE-427601",
"REACTOME:R-DRE-428643",
"REACTOME:R-HSA-196780",
"REACTOME:R-HSA-196807",
"REACTOME:R-HSA-199220",
"REACTOME:R-HSA-209968",
"REACTOME:R-HSA-425... | 27 | [
"5nv9",
"5nva",
"7sl9",
"7uuy",
"7uuz",
"7uv0"
] | 6 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
5,
10614,
13932,
230
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
18,
39,
19,
10,
15
] | 6 | true | Family | Sodium:Solute Symporter (SSF) | Sodium:Solute Symporter (SSF) | Sodium:Solute_Symporter_SSF | 7 |
IPR051164 | 51,164 | NmrA-like oxidoreductase | NmrA-like_oxidored | Family | 25,658 | true | false | The NmrA-like family is composed of redox sensor proteins that undergo structural and subcellular changes in response to intracellular NADPH/NADP(+) levels. These proteins can exist as monomers or dimers, with their oligomeric state influenced by NADPH concentrations. As monomers, they interact with argininosuccinate s... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR42748"
] | [
"NmrA-like_oxidored"
] | [
25658
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-70635",
"R-HSA-70635",
"R-MMU-70635"
] | [
"REACTOME:R-BTA-70635",
"REACTOME:R-HSA-70635",
"REACTOME:R-MMU-70635"
] | 3 | [
"1k6i",
"1k6j",
"1k6x",
"1ti7",
"1xgk",
"2exx",
"2vus",
"2vut",
"2vuu",
"2wm3",
"2wmd",
"3dxf",
"3e5m",
"5f5l",
"5f5n",
"7uf8"
] | 16 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halobacteriales",
"Klosneuvirinae",
"metagenomes"
] | [
7920,
17624,
86,
2,
26
] | 5 | [
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus"
] | [
7,
3,
7,
6
] | 4 | true | Family | NmrA-like oxidoreductase | NmrA-like oxidoreductase | NmrA-like_oxidored | 6 |
IPR051165 | 51,165 | Multifunctional Ankyrin Repeat Domain-Containing Protein | Multifunctional_ANK_Repeat | Family | 31,162 | true | false | This family of proteins includes members involved in various cellular processes such as translational fidelity, neurotransmitter release, symbiosis, ubiquitination, mycotoxin biosynthesis, membrane stabilization, ion transport, endocytosis, protein transport, and phosphoprotein substrate recognition. Some proteins in t... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR24123"
] | [
"Multifunctional_ANK_Repeat"
] | [
31162
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DRE-8951664",
"R-DRE-983168",
"R-HSA-445095",
"R-HSA-447038",
"R-HSA-447041",
"R-HSA-447043",
"R-HSA-6807878",
"R-HSA-9013405",
"R-HSA-9768727",
"R-MMU-445095",
"R-MMU-447043",
"R-MMU-6807878",
"R-RNO-8951664",
"R-RNO-983168"
] | [
"REACTOME:R-DRE-8951664",
"REACTOME:R-DRE-983168",
"REACTOME:R-HSA-445095",
"REACTOME:R-HSA-447038",
"REACTOME:R-HSA-447041",
"REACTOME:R-HSA-447043",
"REACTOME:R-HSA-6807878",
"REACTOME:R-HSA-9013405",
"REACTOME:R-HSA-9768727",
"REACTOME:R-MMU-445095",
"REACTOME:R-MMU-447043",
"REACTOME:R-MMU... | 14 | [
"1n11",
"2yqf",
"2yvi",
"3f59",
"3kbt",
"3kbu",
"3ud1",
"3ud2",
"4d8o",
"4o6x",
"5y4f",
"6m3p",
"6m3q",
"6m3r",
"7tw3",
"7tw5",
"7tw6",
"7uzu",
"7v0k",
"7v0m",
"7v0s",
"7v0x",
"8cs9",
"8csl",
"8csv",
"8cte",
"9e5c"
] | 27 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
11,
1083,
29736,
295,
37
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
5,
17,
294,
30,
111,
49,
3,
4,
52,
8
] | 10 | true | Family | Multifunctional Ankyrin Repeat Domain-Containing Protein | Multifunctional Ankyrin Repeat Domain-Containing Protein | Multifunctional_ANK_Repeat | 8 |
IPR051166 | 51,166 | Threonine Synthase | Threonine_Synthase | Family | 16,228 | true | false | The Threonine Synthase family is characterized by enzymes that catalyze the final step in the biosynthesis of L-threonine from L-phosphohomoserine through a gamma-elimination of phosphate and beta-addition of water. Additionally, some family members possess catabolic phospho-lyase activity, degrading O-phospho-threonin... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR42690"
] | [
"Threonine_Synthase"
] | [
16228
] | 1 | [
"EC"
] | [
"4.2.3.1"
] | [
"EC:4.2.3.1"
] | 1 | [
"1kl7",
"1vb3",
"3v7n",
"4f4f"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
30,
12412,
3531,
255
] | 4 | [
"Danio rerio",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
2,
1,
4,
2,
1,
5,
1,
1
] | 8 | true | Family | Threonine Synthase | Threonine Synthase | Threonine_Synthase | 4 |
IPR051167 | 51,167 | Prolyl oligopeptidase and macrocyclase | Prolyl_oligopep/macrocyclase | Family | 16,729 | true | false | The Prolyl oligopeptidase family, part of the peptidase S9A and S9B subfamilies, encompasses enzymes with diverse functions including conventional prolyl endopeptidases that cleave peptide bonds on the C-terminal side of prolyl residues within short peptides, and specialized macrocyclase-peptidases involved in the bios... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR42881"
] | [
"Prolyl_oligopep/macrocyclase"
] | [
16729
] | 1 | [
"EC"
] | [
"3.4.21.26"
] | [
"EC:3.4.21.26"
] | 1 | [
"1e5t",
"1e8m",
"1e8n",
"1h2w",
"1h2x",
"1h2y",
"1h2z",
"1o6f",
"1o6g",
"1qfm",
"1qfs",
"1uoo",
"1uop",
"1uoq",
"1vz2",
"1vz3",
"1yr2",
"2bkl",
"2xdw",
"3ddu",
"3eq7",
"3eq8",
"3eq9",
"3iuj",
"3iul",
"3ium",
"3iun",
"3iuq",
"3iur",
"3ivm",
"3mun",
"3muo"... | 68 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified Klosneuvirinae",
"unclassified sequences"
] | [
147,
10806,
5609,
2,
165
] | 5 | [
"Arabidopsis thaliana",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
14,
4,
7,
4,
5,
5,
6,
19
] | 8 | true | Family | Prolyl oligopeptidase and macrocyclase | Prolyl oligopeptidase and macrocyclase | Prolyl_oligopep/macrocyclase | 1 |
IPR051168 | 51,168 | Alpha-aminoadipic semialdehyde synthase | AASS | Family | 14,950 | true | false | The Alpha-aminoadipic semialdehyde synthase family comprises bifunctional enzymes involved in lysine degradation. Members of the family catalyze the first two steps of this process, which involve the conversion of lysine to alpha-aminoadipic semialdehyde via the lysine ketoglutarate reductase activity and subsequently ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR11133"
] | [
"AASS"
] | [
14950
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"1.5.1",
"R-BTA-71064",
"R-HSA-71064",
"R-MMU-71064",
"R-RNO-71064",
"R-SCE-71064",
"R-SPO-71064"
] | [
"EC:1.5.1",
"REACTOME:R-BTA-71064",
"REACTOME:R-HSA-71064",
"REACTOME:R-MMU-71064",
"REACTOME:R-RNO-71064",
"REACTOME:R-SCE-71064",
"REACTOME:R-SPO-71064"
] | 7 | [
"1e5l",
"1e5q",
"1ff9",
"2axq",
"2q99",
"2qrj",
"2qrk",
"2qrl",
"3abi",
"3ugk",
"3uh1",
"3uha",
"5l76",
"5l78",
"5o1n",
"5o1o",
"5o1p",
"8dda",
"8e8t",
"8e8u",
"8e8v"
] | 21 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Tupanvirus",
"unclassified sequences"
] | [
110,
6252,
8433,
4,
151
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
6,
2,
14,
2,
16,
4,
2,
8,
9,
2,
2,
47
] | 12 | true | Family | Alpha-aminoadipic semialdehyde synthase | Alpha-aminoadipic semialdehyde synthase | AASS | 9 |
IPR051169 | 51,169 | NADH:quinone oxidoreductase/NAD(P)H-quinone oxidoreductase | NADH-Q_oxidoreductase | Family | 21,032 | true | false | This family of proteins includes enzymes that participate in the electron transport chain by catalyzing the oxidation of NADH and the reduction of quinones. These activities are crucial for the regeneration of NAD+, which is essential for various metabolic processes. Some members of this family are involved in alternat... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR42913"
] | [
"NADH-Q_oxidoreductase"
] | [
21032
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC"
] | [
"1.6.5.9",
"PWY-7269",
"PWY-7279",
"PWY-7998"
] | [
"EC:1.6.5.9",
"METACYC:PWY-7269",
"METACYC:PWY-7279",
"METACYC:PWY-7998"
] | 4 | [
"3hyv",
"3hyw",
"3hyx",
"3kpk",
"3sx6",
"3sxi",
"3sy4",
"3syi",
"3sz0",
"3szc",
"3szf",
"3szw",
"3t0k",
"3t14",
"3t2k",
"3t2y",
"3t2z",
"3t31",
"4nwz",
"5kmp",
"5kmq",
"5kmr",
"5kms",
"5na1",
"5na4",
"5wed",
"6bdo"
] | 27 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
701,
18952,
1236,
143
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
2,
1,
3,
8
] | 4 | true | Family | NADH:quinone oxidoreductase/NAD(P)H-quinone oxidoreductase | NADH:quinone oxidoreductase/NAD(P)H-quinone oxidoreductase | NADH-Q_oxidoreductase | 1 |
IPR051170 | 51,170 | Neural and epithelial cell adhesion domain-containing protein | Neural/epithelial_adhesion | Family | 29,054 | true | false | This family of proteins includes cell adhesion molecules that are primarily involved in neural development and function. They play crucial roles in neuron-neuron adhesion, neurite outgrowth, fasciculation, and the development of nerve fascicles. Some members are implicated in maintaining the integrity of the trans-epit... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12231"
] | [
"Neural/epithelial_adhesion"
] | [
29054
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-DME-1474228",
"R-DME-1971475",
"R-DME-2022928",
"R-DME-2024096",
"R-DME-216083",
"R-DME-3000171",
"R-DME-3000178",
"R-HSA-1474228",
"R-HSA-1971475",
"R-HSA-2022928",
"R-HSA-2024096",
"R-HSA-210991",
"R-HSA-216083",
"R-HSA-3000157",
"R-HSA-3000171",
"R-HSA-3000178",
"R-HSA-3560783"... | [
"REACTOME:R-DME-1474228",
"REACTOME:R-DME-1971475",
"REACTOME:R-DME-2022928",
"REACTOME:R-DME-2024096",
"REACTOME:R-DME-216083",
"REACTOME:R-DME-3000171",
"REACTOME:R-DME-3000178",
"REACTOME:R-HSA-1474228",
"REACTOME:R-HSA-1971475",
"REACTOME:R-HSA-2022928",
"REACTOME:R-HSA-2024096",
"REACTOME... | 60 | [
"1gl4",
"1uen",
"1ujt",
"2e9w",
"2ec8",
"2jll",
"2v5r",
"2v9q",
"2v9r",
"2vkw",
"2vkx",
"2xyc",
"3mtr",
"3qqn",
"3qr2",
"4hlj",
"5eo9",
"5ftt",
"5oyj",
"6efy",
"6efz",
"6eg0",
"6eg1",
"6fey",
"6ff3",
"6i9s",
"6iaa",
"6nrq",
"6nrr",
"6ns1",
"7za1",
"7za2"... | 36 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
23,
29018,
8,
5
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
16,
144,
40,
66,
39,
74
] | 6 | true | Family | Neural and epithelial cell adhesion domain-containing protein | Neural and epithelial cell adhesion domain-containing protein | Neural/epithelial_adhesion | 4 |
IPR051171 | 51,171 | Calcium/Cation Antiporter | CaCA | Family | 15,344 | true | false | The Ca(2+):cation antiporter (CaCA) family is involved in the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Members of this family mediate the exchange of Ca(2+) ions against various cations, such as Na(+) or protons, across the cell membrane. This exchange contributes to processes su... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR11878"
] | [
"CaCA"
] | [
15344
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CFA-418359",
"R-CFA-425561",
"R-CFA-5578775",
"R-HSA-418359",
"R-HSA-425561",
"R-HSA-5578775",
"R-HSA-8949215",
"R-MMU-418359",
"R-MMU-425561",
"R-MMU-5578775",
"R-RNO-418359",
"R-RNO-425561",
"R-RNO-5578775"
] | [
"REACTOME:R-CFA-418359",
"REACTOME:R-CFA-425561",
"REACTOME:R-CFA-5578775",
"REACTOME:R-HSA-418359",
"REACTOME:R-HSA-425561",
"REACTOME:R-HSA-5578775",
"REACTOME:R-HSA-8949215",
"REACTOME:R-MMU-418359",
"REACTOME:R-MMU-425561",
"REACTOME:R-MMU-5578775",
"REACTOME:R-RNO-418359",
"REACTOME:R-RNO... | 13 | [
"2dpk",
"2fws",
"2fwu",
"2kls",
"2klt",
"2lt9",
"2qvk",
"2qvm",
"3e9t",
"3e9u",
"3ead",
"3gin",
"3rb5",
"3rb7",
"3us9",
"8jp0",
"8sgi",
"8sgj",
"8sgt",
"9iv8"
] | 20 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"Methanocellaceae",
"metagenomes"
] | [
1934,
8,
13319,
9,
74
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
3,
9,
81,
7,
25,
22,
4,
30,
15
] | 9 | true | Family | Calcium/Cation Antiporter | Calcium/Cation Antiporter | CaCA | 3 |
IPR051172 | 51,172 | Chlamydia Large Cysteine-rich Periplasmic OmcB | Chlamydia_OmcB | Family | 9,148 | true | false | The OmcB protein family consists of large cysteine-rich periplasmic proteins found in Chlamydia species. These proteins play a crucial role in the structural integrity of the outer envelope of elementary bodies (EBs), which are the infectious form of the bacteria. OmcB proteins achieve this by forming disulfide cross-l... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR34819"
] | [
"Chlamydia_OmcB"
] | [
9148
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Tupanvirus",
"unclassified sequences"
] | [
334,
8648,
32,
4,
130
] | 5 | [] | [] | 0 | true | Family | Chlamydia Large Cysteine-rich Periplasmic OmcB | Chlamydia Large Cysteine-rich Periplasmic OmcB | Chlamydia_OmcB | 9 |
IPR051173 | 51,173 | Voltage-dependent calcium channel subunit alpha-2/delta | Ca_channel_alpha-2/delta | Family | 15,981 | true | false | The calcium channel subunit alpha-2/delta family comprises proteins that act as regulatory subunits for voltage-dependent calcium channels, influencing calcium current density and activation/inactivation kinetics. These subunits are involved in various calcium-dependent processes, including excitation-contraction coupl... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR10166"
] | [
"Ca_channel_alpha-2/delta"
] | [
15981
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-112308",
"R-CEL-422356",
"R-CEL-5576892",
"R-CEL-5576893",
"R-HSA-112308",
"R-HSA-400042",
"R-HSA-422356",
"R-HSA-5576892",
"R-HSA-5576893",
"R-HSA-9662360",
"R-HSA-9856532",
"R-MMU-112308",
"R-MMU-422356",
"R-MMU-5576892",
"R-MMU-5576893",
"R-RNO-112308",
"R-RNO-422356",
"R... | [
"REACTOME:R-CEL-112308",
"REACTOME:R-CEL-422356",
"REACTOME:R-CEL-5576892",
"REACTOME:R-CEL-5576893",
"REACTOME:R-HSA-112308",
"REACTOME:R-HSA-400042",
"REACTOME:R-HSA-422356",
"REACTOME:R-HSA-5576892",
"REACTOME:R-HSA-5576893",
"REACTOME:R-HSA-9662360",
"REACTOME:R-HSA-9856532",
"REACTOME:R-M... | 19 | [
"3jbr",
"5gjv",
"5gjw",
"5lt9",
"5lto",
"5ltx",
"5t65",
"5t7m",
"6jp5",
"6jp8",
"6jpa",
"6jpb",
"6pxy",
"6py3",
"6py4",
"6py5",
"6pyi",
"6q0f",
"6q0g",
"7jpk",
"7jpl",
"7jpv",
"7jpw",
"7jpx",
"7mix",
"7miy",
"7uhf",
"7uhg",
"7vfs",
"7vfu",
"7vfv",
"7vfw"... | 61 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Klosneuvirinae",
"unclassified sequences"
] | [
8,
1512,
14453,
2,
6
] | 5 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
50,
10,
1,
28,
18,
29
] | 7 | true | Family | Voltage-dependent calcium channel subunit alpha-2/delta | Voltage-dependent calcium channel subunit alpha-2/delta | Ca_channel_alpha-2/delta | 1 |
IPR051174 | 51,174 | Cytochrome c-type Electron Transfer | Cytochrome_c-type_ET | Family | 7,704 | true | false | This family of proteins is involved in electron transfer processes within the cell, particularly in anaerobic respiration. Members of this family are typically cytochrome c-type proteins that mediate electron flow from quinones to various complexes, such as the NapAB complex in nitrate reduction and the TorA or TorZ en... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR30333"
] | [
"Cytochrome_c-type_ET"
] | [
7704
] | 1 | [] | [] | [] | 0 | [
"2j7a",
"2vr0",
"6ef8",
"6nef"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Methanoperedens nitratireducens",
"Opisthokonta",
"metagenomes"
] | [
7592,
4,
7,
101
] | 4 | [
"Escherichia coli (strain K12)"
] | [
3
] | 1 | true | Family | Cytochrome c-type Electron Transfer | Cytochrome c-type Electron Transfer | Cytochrome_c-type_ET | 2 |
IPR051177 | 51,177 | Catalytically Inactive Kinase-Related Protein | CIK-Related_Protein | Family | 13,395 | true | false | This family of proteins includes members that are structurally related to the protein kinase superfamily but are predicted to be catalytically inactive. Despite the lack of detectable kinase activity, these proteins are implicated in various cellular processes. Some family members are involved in the regulation of COPI... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12984"
] | [
"CIK-Related_Protein"
] | [
13395
] | 1 | [] | [] | [] | 0 | [
"3vwa"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Mesorhizobium kowhaii"
] | [
13394,
1
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
16,
5,
3,
10,
16,
11,
2,
8,
13,
2,
2,
71
] | 12 | true | Family | Catalytically Inactive Kinase-Related Protein | Catalytically Inactive Kinase-Related Protein | CIK-Related_Protein | 4 |
IPR051178 | 51,178 | TfdA dioxygenase | TfdA_dioxygenase | Family | 6,766 | true | false | The TfdA dioxygenase family is involved in various oxidative decarboxylation and hydroxylation reactions that are crucial for the metabolism of diverse substrates, including herbicides, fatty acids, and purines. Members of this family play roles in the biosynthesis of isonitrile lipopeptides, which are implicated in vi... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43779"
] | [
"TfdA_dioxygenase"
] | [
6766
] | 1 | [
"EC"
] | [
"1.14.11"
] | [
"EC:1.14.11"
] | 1 | [
"5bke",
"5j92",
"6dch",
"6l6w",
"6l6x",
"6l86",
"6xn6",
"6xo3",
"6xoj",
"6xpa",
"7scp",
"8kht",
"8kif"
] | 13 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes",
"uncultured Caudovirales phage",
"uncultured marine group III euryarchaeote KM3-28-E8"
] | [
2968,
3697,
93,
7,
1
] | 5 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
2,
1
] | 2 | true | Family | TfdA dioxygenase | TfdA dioxygenase | TfdA_dioxygenase | 5 |
IPR051179 | 51,179 | Multifunctional WD repeat-containing protein | WD_repeat_multifunction | Family | 8,782 | true | false | This family of proteins is involved in various cellular processes, including angiogenesis, cell migration, mitochondrial fission, and the regulation of proteasome assembly and activity. Some members act as adapter proteins that facilitate the formation of mitochondrial fission complexes, which are essential for the div... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR19857"
] | [
"WD_repeat_multifunction"
] | [
8782
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-168638",
"R-BTA-177929",
"R-BTA-428930",
"R-CFA-168638",
"R-CFA-177929",
"R-CFA-428930",
"R-HSA-168638",
"R-HSA-177929",
"R-HSA-194138",
"R-HSA-428930",
"R-HSA-9907900"
] | [
"REACTOME:R-BTA-168638",
"REACTOME:R-BTA-177929",
"REACTOME:R-BTA-428930",
"REACTOME:R-CFA-168638",
"REACTOME:R-CFA-177929",
"REACTOME:R-CFA-428930",
"REACTOME:R-HSA-168638",
"REACTOME:R-HSA-177929",
"REACTOME:R-HSA-194138",
"REACTOME:R-HSA-428930",
"REACTOME:R-HSA-9907900"
] | 11 | [
"3acp",
"3vl1",
"4zn4",
"4zov",
"4zox",
"4zoy",
"4zoz",
"5ams"
] | 8 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriati",
"Mimivirus",
"ecological metagenomes"
] | [
448,
8310,
10,
6,
8
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
17,
4,
1,
2,
14,
7,
1,
9,
4,
4,
1,
27
] | 12 | true | Family | Multifunctional WD repeat-containing protein | Multifunctional WD repeat-containing protein | WD_repeat_multifunction | 3 |
IPR051180 | 51,180 | Inhibitor of nuclear factor kappa-B kinase | IKK | Family | 7,566 | true | false | The I-kappa-B kinase (IKK) family comprises serine/threonine kinases essential for the NF-kappa-B signaling pathway, which is activated by various stimuli including inflammatory cytokines, bacterial or viral products, DNA damage, and other cellular stresses. Family members phosphorylate inhibitors of NF-kappa-B, leadin... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR22969"
] | [
"IKK"
] | [
7566
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
... | [
"2.7.11.10",
"R-BTA-1169091",
"R-BTA-1810476",
"R-BTA-202424",
"R-BTA-209543",
"R-BTA-209560",
"R-BTA-2871837",
"R-BTA-445989",
"R-BTA-5357905",
"R-BTA-5357956",
"R-BTA-5607761",
"R-BTA-5607764",
"R-BTA-5676590",
"R-BTA-5684264",
"R-BTA-9020702",
"R-BTA-933542",
"R-BTA-937039",
"R-... | [
"EC:2.7.11.10",
"REACTOME:R-BTA-1169091",
"REACTOME:R-BTA-1810476",
"REACTOME:R-BTA-202424",
"REACTOME:R-BTA-209543",
"REACTOME:R-BTA-209560",
"REACTOME:R-BTA-2871837",
"REACTOME:R-BTA-445989",
"REACTOME:R-BTA-5357905",
"REACTOME:R-BTA-5357956",
"REACTOME:R-BTA-5607761",
"REACTOME:R-BTA-560776... | 157 | [
"3qa8",
"3rzf",
"4e3c",
"4efo",
"4eut",
"4euu",
"4im0",
"4im2",
"4im3",
"4iw0",
"4iwo",
"4iwp",
"4iwq",
"4jl9",
"4jlc",
"4kik",
"5ebz",
"5tqw",
"5tqx",
"5tqy",
"5w5v",
"6bny",
"6bod",
"6boe",
"6cq0",
"6cq4",
"6cq5",
"6nt9",
"6o8b",
"6o8c",
"6rsr",
"6rst"... | 34 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"marine sediment metagenome"
] | [
7565,
1
] | 2 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
9,
4,
53,
27,
18
] | 5 | true | Family | Inhibitor of nuclear factor kappa-B kinase | Inhibitor of nuclear factor kappa-B kinase | IKK | 2 |
IPR051181 | 51,181 | CAF1 family poly(A)-specific ribonucleases | CAF1_poly(A)_ribonucleases | Family | 7,873 | true | false | The CAF1 family proteins are specialized 3'-exoribonucleases with a preference for degrading poly(A) tails of mRNAs, a key step in eukaryotic mRNA decay. They play roles in various biological processes including translational silencing of maternal mRNAs during oocyte maturation and early embryonic development, nonsense... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR15092"
] | [
"CAF1_poly(A)_ribonucleases"
] | [
7873
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"3.1.13.4",
"R-HSA-380994",
"R-HSA-429947",
"R-HSA-450604",
"R-MMU-429947",
"R-MMU-450604"
] | [
"EC:3.1.13.4",
"REACTOME:R-HSA-380994",
"REACTOME:R-HSA-429947",
"REACTOME:R-HSA-450604",
"REACTOME:R-MMU-429947",
"REACTOME:R-MMU-450604"
] | 6 | [
"1ug8",
"1whv",
"2a1r",
"2a1s",
"2rok",
"3ctr",
"3d45"
] | 7 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
7873
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea... | [
10,
2,
5,
25,
12,
1,
7,
25,
1,
15
] | 10 | true | Family | CAF1 family poly(A)-specific ribonucleases | CAF1 family poly(A)-specific ribonucleases | CAF1_poly(A)_ribonucleases | 8 |
IPR051182 | 51,182 | Eukaryotic NMN adenylyltransferase | Euk_NMN_adenylyltrnsfrase | Family | 7,556 | true | false | The eukaryotic NMN adenylyltransferase family is responsible for the biosynthesis of NAD(+) from nicotinamide mononucleotide (NMN) and ATP, a key step in both de novo and salvage pathways for NAD(+) production. Members of the family can also utilize the deamidated form, nicotinic acid mononucleotide (NaMN), with varyin... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12039"
] | [
"Euk_NMN_adenylyltrnsfrase"
] | [
7556
] | 1 | [
"EC",
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.7.7.1",
"2.7.7.18",
"PWY-5381",
"PWY-5653",
"PWY-7761",
"PWY-8277",
"PWY-8352",
"R-BTA-196807",
"R-CEL-196807",
"R-DME-196807",
"R-DRE-196807",
"R-HSA-196807",
"R-MMU-196807",
"R-RNO-196807",
"R-SCE-196807",
"R-SPO-196807"
] | [
"EC:2.7.7.1",
"EC:2.7.7.18",
"METACYC:PWY-5381",
"METACYC:PWY-5653",
"METACYC:PWY-7761",
"METACYC:PWY-8277",
"METACYC:PWY-8352",
"REACTOME:R-BTA-196807",
"REACTOME:R-CEL-196807",
"REACTOME:R-DME-196807",
"REACTOME:R-DRE-196807",
"REACTOME:R-HSA-196807",
"REACTOME:R-MMU-196807",
"REACTOME:R... | 16 | [
"1gzu",
"1kku",
"1kqn",
"1kqo",
"1kr2",
"1nup",
"1nuq",
"1nur",
"1nus",
"1nut",
"1nuu",
"5z9r",
"8qe8",
"9iw1",
"9rpk",
"9rpm"
] | 16 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses"
] | [
13,
7537,
6
] | 3 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
8,
2,
7,
1,
17,
13,
1,
7,
18,
2,
1,
6
] | 12 | true | Family | Eukaryotic NMN adenylyltransferase | Eukaryotic NMN adenylyltransferase | Euk_NMN_adenylyltrnsfrase | 2 |
IPR051183 | 51,183 | U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa | U1_U11-U12_snRNP_70-35kDa | Family | 7,940 | true | false | The protein family is involved in the splicing of pre-mRNA, a critical step in gene expression where introns are removed and exons are joined to form a mature mRNA molecule. Members of the family are components of the spliceosomal U1 small nuclear ribonucleoprotein (snRNP) complex, which recognizes the pre-mRNA 5' spli... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR13952"
] | [
"U1_U11-U12_snRNP_70-35kDa"
] | [
7940
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-72165",
"R-HSA-72163",
"R-HSA-72165",
"R-MMU-72163",
"R-MMU-72165",
"R-RNO-72165"
] | [
"REACTOME:R-BTA-72165",
"REACTOME:R-HSA-72163",
"REACTOME:R-HSA-72165",
"REACTOME:R-MMU-72163",
"REACTOME:R-MMU-72165",
"REACTOME:R-RNO-72165"
] | 6 | [
"3cw1",
"3pgw",
"4pkd",
"5zwn",
"6g90",
"6n7p",
"6n7r",
"6n7x",
"6qx9",
"7b0y",
"7oqc",
"7oqe",
"7vpx",
"8r08",
"8r7n",
"8w2o",
"8y6o",
"9gbw",
"9gbz",
"9gcm",
"9qeq"
] | 21 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
3,
7937
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
44,
1,
4,
2,
5,
11,
1,
13,
9,
1,
1,
14
] | 12 | true | Family | U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa | U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa | U1_U11-U12_snRNP_70-35kDa | 9 |
IPR051184 | 51,184 | Tyrosine-phosphorylated adapter molecule | Tyrosine-phos_adapter | Family | 6,549 | true | false | This family of proteins includes adapter molecules that play a crucial role in signal transduction pathways. They are involved in various cellular processes such as cell adhesion, migration, branching, and apoptosis. These proteins typically associate with tyrosine-phosphorylated receptors or substrates, mediating down... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR19969"
] | [
"Tyrosine-phos_adapter"
] | [
6549
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-CEL-186763",
"R-CEL-8849471",
"R-CEL-8875555",
"R-CEL-8875656",
"R-CEL-912631",
"R-DME-186763",
"R-DME-202433",
"R-DME-2029482",
"R-DME-373753",
"R-DME-3928664",
"R-DME-418885",
"R-DME-4420097",
"R-DME-5663213",
"R-DME-8849471",
"R-DME-9013420",
"R-DME-9013424",
"R-DME-9027284",
... | [
"REACTOME:R-CEL-186763",
"REACTOME:R-CEL-8849471",
"REACTOME:R-CEL-8875555",
"REACTOME:R-CEL-8875656",
"REACTOME:R-CEL-912631",
"REACTOME:R-DME-186763",
"REACTOME:R-DME-202433",
"REACTOME:R-DME-2029482",
"REACTOME:R-DME-373753",
"REACTOME:R-DME-3928664",
"REACTOME:R-DME-418885",
"REACTOME:R-DM... | 83 | [
"1a07",
"1a08",
"1a09",
"1a1a",
"1a1b",
"1a1c",
"1a1e",
"1a81",
"1ab2",
"1aot",
"1aou",
"1b07",
"1bkl",
"1bkm",
"1cka",
"1ckb",
"1csy",
"1csz",
"1f1w",
"1f2f",
"1hcs",
"1hct",
"1is0",
"1ju5",
"1jwo",
"1kc2",
"1m30",
"1m3a",
"1m3b",
"1m3c",
"1m61",
"1nzl"... | 155 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Viruses"
] | [
6543,
6
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
5,
24,
9,
26,
25,
14
] | 6 | true | Family | Tyrosine-phosphorylated adapter molecule | Tyrosine-phosphorylated adapter molecule | Tyrosine-phos_adapter | 7 |
IPR051185 | 51,185 | Abnormal Spindle-like Microcephaly-associated | ASPM | Family | 6,147 | true | false | The Abnormal Spindle-like Microcephaly-associated (ASPM) protein family is involved in the regulation and coordination of mitotic spindle dynamics during cell division. Members of this family play a crucial role in maintaining the structure of the centrosomal microtubule organizing center (MTOC) and are essential for p... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR22706"
] | [
"ASPM"
] | [
6147
] | 1 | [] | [] | [] | 0 | [
"7n6g",
"7sqc",
"9ijj"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Candidatus Comchoanobacter bicostacola",
"Eukaryota"
] | [
1,
6146
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
7,
1,
5,
9,
9,
2,
4,
5,
16
] | 9 | true | Family | Abnormal Spindle-like Microcephaly-associated | Abnormal Spindle-like Microcephaly-associated | ASPM | 8 |
IPR051186 | 51,186 | RRM HNRPC family, RALY subfamily | RRM_HNRPC/RALY_subfam | Family | 6,174 | true | false | The RRM HNRPC family, RALY subfamily, comprises RNA-binding proteins involved in various aspects of RNA metabolism. Members of this family bind to pre-mRNA and are implicated in the assembly of hnRNP particles, playing a role in mRNA stability, translation, and splicing. They interact with poly-U tracts in mRNA UTRs an... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR13968"
] | [
"RRM_HNRPC/RALY_subfam"
] | [
6174
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-4570464",
"R-HSA-72163",
"R-HSA-72203",
"R-HSA-9013418",
"R-HSA-9013422",
"R-MMU-4570464",
"R-MMU-72163",
"R-MMU-72203",
"R-MMU-9013418",
"R-MMU-9013422",
"R-RNO-4570464",
"R-RNO-72163",
"R-RNO-72203",
"R-RNO-9013418",
"R-RNO-9013422",
"R-SCE-4570464",
"R-SCE-72203",
"R-SPO-... | [
"REACTOME:R-HSA-4570464",
"REACTOME:R-HSA-72163",
"REACTOME:R-HSA-72203",
"REACTOME:R-HSA-9013418",
"REACTOME:R-HSA-9013422",
"REACTOME:R-MMU-4570464",
"REACTOME:R-MMU-72163",
"REACTOME:R-MMU-72203",
"REACTOME:R-MMU-9013418",
"REACTOME:R-MMU-9013422",
"REACTOME:R-RNO-4570464",
"REACTOME:R-RNO-... | 20 | [
"1wf1",
"1wf2",
"2kvi",
"2l41",
"2mxy",
"2mz1",
"2xnq",
"2xnr"
] | 8 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"bird metagenome"
] | [
6173,
1
] | 2 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
46,
2,
44,
18,
1,
21,
1,
1
] | 8 | true | Family | RRM HNRPC family, RALY subfamily | RRM HNRPC family, RALY subfamily | RRM_HNRPC/RALY_subfam | 3 |
IPR051187 | 51,187 | Pre-mRNA 3'-end-processing regulator | Pre-mRNA_3'-end_processing_reg | Family | 5,740 | true | false | This family of proteins is involved in the regulation of pre-mRNA 3'-end processing, a crucial step in mRNA maturation. Members of this family are key components of the cleavage and polyadenylation specificity factor (CPSF) complex, which recognizes specific signal sequences in pre-mRNA and interacts with poly(A) polym... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR13484"
] | [
"Pre-mRNA_3'-end_processing_reg"
] | [
5740
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-159231",
"R-HSA-72187",
"R-HSA-72203",
"R-HSA-73856",
"R-HSA-77595",
"R-HSA-9673766",
"R-MMU-159231",
"R-MMU-72187",
"R-MMU-72203",
"R-MMU-73856",
"R-MMU-77595",
"R-RNO-159231",
"R-RNO-72187",
"R-RNO-72203",
"R-RNO-73856",
"R-RNO-77595",
"R-SPO-159231",
"R-SPO-77595"
] | [
"REACTOME:R-HSA-159231",
"REACTOME:R-HSA-72187",
"REACTOME:R-HSA-72203",
"REACTOME:R-HSA-73856",
"REACTOME:R-HSA-77595",
"REACTOME:R-HSA-9673766",
"REACTOME:R-MMU-159231",
"REACTOME:R-MMU-72187",
"REACTOME:R-MMU-72203",
"REACTOME:R-MMU-73856",
"REACTOME:R-MMU-77595",
"REACTOME:R-RNO-159231",
... | 18 | [
"7k95",
"7zyh"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Halolamina litorea",
"Viruses",
"viral metagenome"
] | [
17,
5718,
1,
3,
1
] | 5 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strai... | [
2,
13,
1,
45,
2,
2,
9,
1,
1
] | 9 | true | Family | Pre-mRNA 3'-end-processing regulator | Pre-mRNA 3'-end-processing regulator | Pre-mRNA_3'-end_processing_reg | 5 |
IPR051188 | 51,188 | PHD-type Zinc Finger Domain-Containing Protein | PHD-type_Zinc_Finger | Family | 5,474 | true | false | This family of proteins includes regulators of transcription and ubiquitination processes. Members are involved in the regulation of Th1-type cytokine gene expression, which suggests a role in immune response modulation. Some proteins within this family function as E3 ubiquitin-protein ligases, accepting ubiquitin from... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12420"
] | [
"PHD-type_Zinc_Finger"
] | [
5474
] | 1 | [] | [] | [] | 0 | [
"1weq",
"4nn2",
"8jwj",
"8jws",
"8jwu"
] | 5 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
5474
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
37,
2,
35,
14,
25
] | 5 | true | Family | PHD-type Zinc Finger Domain-Containing Protein | PHD-type Zinc Finger Domain-Containing Protein | PHD-type_Zinc_Finger | 5 |
IPR051189 | 51,189 | Splicing-associated domain-containing protein | Splicing_assoc_domain | Family | 4,775 | true | false | This family of proteins appears to be primarily involved in the process of splicing, with several members having annotations suggesting a role in this fundamental aspect of gene expression. Splicing is a critical step in the post-transcriptional modification of RNA, where introns are removed and exons are joined to for... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR14195"
] | [
"Splicing_assoc_domain"
] | [
4775
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
4775
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
2,
2,
8,
10,
1,
16,
1,
2
] | 8 | true | Family | Splicing-associated domain-containing protein | Splicing-associated domain-containing protein | Splicing_assoc_domain | 7 |
IPR051190 | 51,190 | Baculoviral IAP repeat-containing | Baculoviral_IAP | Family | 4,241 | true | false | The Baculoviral IAP repeat-containing protein family is involved in various cellular processes, primarily acting as a key component of the chromosomal passenger complex (CPC), which is crucial for chromosome alignment, segregation during mitosis, and cytokinesis. Family members are multitasking proteins that promote ce... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR46771"
] | [
"Baculoviral_IAP"
] | [
4241
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-141444",
"R-BTA-2467813",
"R-BTA-2500257",
"R-BTA-4615885",
"R-BTA-5663220",
"R-BTA-68877",
"R-BTA-8951664",
"R-BTA-9648025",
"R-HSA-141444",
"R-HSA-2467813",
"R-HSA-2500257",
"R-HSA-4615885",
"R-HSA-5663220",
"R-HSA-6785807",
"R-HSA-6803205",
"R-HSA-68877",
"R-HSA-8951664",
... | [
"REACTOME:R-BTA-141444",
"REACTOME:R-BTA-2467813",
"REACTOME:R-BTA-2500257",
"REACTOME:R-BTA-4615885",
"REACTOME:R-BTA-5663220",
"REACTOME:R-BTA-68877",
"REACTOME:R-BTA-8951664",
"REACTOME:R-BTA-9648025",
"REACTOME:R-HSA-141444",
"REACTOME:R-HSA-2467813",
"REACTOME:R-HSA-2500257",
"REACTOME:R-... | 47 | [
"1e31",
"1f3h",
"1m4m",
"1xox",
"2qfa",
"2raw",
"2rax",
"3uec",
"3ued",
"3uee",
"3uef",
"3ueg",
"3ueh",
"3uei",
"3uig",
"3uih",
"3uii",
"3uij",
"3uik",
"4a0i",
"4a0j",
"4a0n",
"6sho",
"6yie",
"6yif",
"6yih",
"7lbk",
"7lbo",
"7lbp",
"7lbq",
"8rup",
"9si3"... | 35 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Abalone asfa-like virus",
"Eukaryota"
] | [
1,
4240
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strai... | [
2,
4,
2,
14,
2,
1,
6,
1,
1
] | 9 | true | Family | Baculoviral IAP repeat-containing | Baculoviral IAP repeat-containing | Baculoviral_IAP | 2 |
IPR051191 | 51,191 | DDB1-CUL4-associated factor 12 | DCAF12 | Family | 3,175 | true | false | This family of proteins functions as substrate-recognition components of DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes, which are involved in the DesCEND (destruction via C-end degrons) pathway. They recognize and bind to specific C-degron motifs, typically less than ten residues in length, located at the... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR19860"
] | [
"DCAF12"
] | [
3175
] | 1 | [] | [] | [] | 0 | [
"8ajm",
"8ajn",
"8ajo",
"8t9a"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"marine sediment metagenome"
] | [
229,
2938,
6,
2
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
10,
1,
7,
7,
17
] | 6 | true | Family | DDB1-CUL4-associated factor 12 | DDB1-CUL4-associated factor 12 | DCAF12 | 8 |
IPR051192 | 51,192 | Sprouty domain-containing protein | Sprouty_domain | Family | 3,474 | true | false | This family of proteins functions as modulators of cellular signaling pathways, particularly those mediated by fibroblast growth factors (FGFs) and epidermal growth factor receptor (EGFR). Members of this family are known to inhibit FGF-induced differentiation processes, such as retinal lens fiber differentiation, and ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12365"
] | [
"Sprouty_domain"
] | [
3474
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-1295596",
"R-BTA-182971",
"R-DME-1295596",
"R-DME-182971",
"R-HSA-1295596",
"R-HSA-182971",
"R-MMU-1295596",
"R-MMU-182971"
] | [
"REACTOME:R-BTA-1295596",
"REACTOME:R-BTA-182971",
"REACTOME:R-DME-1295596",
"REACTOME:R-DME-182971",
"REACTOME:R-HSA-1295596",
"REACTOME:R-HSA-182971",
"REACTOME:R-MMU-1295596",
"REACTOME:R-MMU-182971"
] | 8 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eumetazoa"
] | [
3474
] | 1 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
6,
2,
7,
8,
10
] | 5 | true | Family | Sprouty domain-containing protein | Sprouty domain-containing protein | Sprouty_domain | 9 |
IPR051195 | 51,195 | Fungal stress response NST1 | Fungal_stress_NST1 | Family | 2,123 | true | false | The NST1 family comprises stress response proteins that are implicated in the regulation of salt tolerance. Members of the NST1 family are suggested to function as negative regulators of salt tolerance, potentially playing a role in the cellular response to high salinity conditions. In some species, proteins from the N... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR31780"
] | [
"Fungal_stress_NST1"
] | [
2123
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2123
] | 1 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
9,
4,
6,
1,
1,
28
] | 6 | true | Family | Fungal stress response NST1 | Fungal stress response NST1 | Fungal_stress_NST1 | 1 |
IPR051196 | 51,196 | RSAD2 and Viperin antiviral | RSAD2/Viperin_antiviral | Family | 2,166 | true | false | The RSAD2 and Viperin protein family includes enzymes that are involved in the antiviral response of cells. Members of this family catalyze the conversion of nucleotides such as CTP, GTP, and UTP to their dehydrated forms via a SAM-dependent radical mechanism. These modified nucleotides act as chain terminators for vir... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR21339"
] | [
"RSAD2/Viperin_antiviral"
] | [
2166
] | 1 | [
"REACTOME"
] | [
"R-HSA-909733"
] | [
"REACTOME:R-HSA-909733"
] | 1 | [
"5vsl",
"5vsm",
"6b4c",
"6q2p",
"6q2q",
"7n7h",
"7n7i",
"9dfn",
"9dfu",
"9dfw",
"9dgw"
] | 11 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
37,
268,
1848,
13
] | 4 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
5,
3,
4
] | 4 | true | Family | RSAD2 and Viperin antiviral | RSAD2 and Viperin antiviral | RSAD2/Viperin_antiviral | 1 |
IPR051197 | 51,197 | Extracellular matrix-binding protein | ECM-binding_protein | Family | 251 | true | false | This family of proteins is involved in bacterial adhesion processes. Members of this family have been shown to promote bacterial attachment to fibronectin, a glycoprotein that exists in soluble and fibrous forms and plays a critical role in cell adhesion, growth, migration, and differentiation. The interaction with fib... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR33150"
] | [
"ECM-binding_protein"
] | [
251
] | 1 | [] | [] | [] | 0 | [
"2dgj"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
201,
50
] | 2 | [] | [] | 0 | true | Family | Extracellular matrix-binding protein | Extracellular matrix-binding protein | ECM-binding_protein | 3 |
IPR051198 | 51,198 | Tetrapyrrole and bacteriochlorophyll biosynthesis methyltransferases | BchE-like | Family | 27,069 | true | true | This family includes Anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase from Rhodobacter capsulatus (BchE) [ ] and similar radical SAM superfamily proteins that are involved in diverse biosynthetic pathways, including the formation of tetrapyrroles and bacteriochlorophylls, essential components for photosyn... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43409"
] | [
"Tetrapyrrole_Bchl_Biosynth_MTs"
] | [
27069
] | 1 | [] | [] | [] | 0 | [
"4q37",
"5ul2",
"5ul3",
"5ul4",
"6fd2",
"6wte",
"6wtf",
"7kdx",
"7kdy",
"9ccb"
] | 10 | [
"PUB00015453",
"PUB00083634",
"PUB00083675"
] | [
"10841582",
"17586634",
"20421508"
] | [
"Anaerobic chlorophyll isocyclic ring formation in Rhodobacter capsulatus requires a cobalamin cofactor.",
"Bacteriochlorophyllide c C-8(2) and C-12(1) methyltransferases are essential for adaptation to low light in Chlorobaculum tepidum.",
"Identification of a methylase required for 2-methylhopanoid production... | [
2000,
2007,
2010
] | 3 | [] | [
"IPR034466"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"unclassified sequences"
] | [
1154,
23918,
10,
109,
1878
] | 5 | [] | [] | 0 | true | Family | Tetrapyrrole and bacteriochlorophyll biosynthesis methyltransferases | Tetrapyrrole and bacteriochlorophyll biosynthesis methyltransferases | BchE-like | 7 |
IPR051199 | 51,199 | Lipopolysaccharide/Lipooligosaccharide Heptosyltransferase | LPS_LOS_Heptosyltrfase | Family | 37,627 | true | false | The glycosyltransferase 9 family is involved in the biosynthesis of the core oligosaccharide region of lipopolysaccharides (LPS) and lipooligosaccharides (LOS). Members of this family catalyze the addition of heptose units to the Kdo2-lipid A module, which is a critical step in the formation of the LPS and LOS structur... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR30160"
] | [
"LPS_LOS_Heptosyltrfase"
] | [
37627
] | 1 | [
"EC"
] | [
"2.4.99"
] | [
"EC:2.4.99"
] | 1 | [
"1psw",
"2gt1",
"2h1f",
"2h1h",
"3tov",
"6dfe"
] | 6 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
44,
36644,
31,
18,
890
] | 5 | [
"Escherichia coli (strain K12)"
] | [
4
] | 1 | true | Family | Lipopolysaccharide/Lipooligosaccharide Heptosyltransferase | Lipopolysaccharide/Lipooligosaccharide Heptosyltransferase | LPS_LOS_Heptosyltrfase | 3 |
IPR051200 | 51,200 | Multi-functional host-pathogen interaction and enzymatic activity protein | Host-pathogen_enzymatic-act | Family | 33,525 | true | false | This family of proteins includes a variety of functions related to host-pathogen interactions, enzymatic activity, and cellular processes. Members are involved in the secretion of factors that may influence host immune responses, such as the maturation and activation of dendritic cells, and the modulation of cytokine p... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR47197"
] | [
"Host-pathogen_enzymatic-act"
] | [
33525
] | 1 | [] | [] | [] | 0 | [
"1aof",
"1aom",
"1aoq",
"1bl9",
"1e2r",
"1gjq",
"1hzu",
"1hzv",
"1jju",
"1jmx",
"1jmz",
"1l0q",
"1n15",
"1n50",
"1n90",
"1nir",
"1nno",
"1pby",
"1qks",
"2h3x",
"2h47",
"2iaa",
"3bws",
"3dsm",
"3u4y",
"3vgz",
"3vh0",
"5c2v",
"5c2w",
"5guw",
"6rtd",
"6rte"... | 59 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
928,
31494,
383,
19,
701
] | 5 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Multi-functional host-pathogen interaction and enzymatic activity protein | Multi-functional host-pathogen interaction and enzymatic activity protein | Host-pathogen_enzymatic-act | 2 |
IPR051201 | 51,201 | Chloroplastic and Bacterial Serine Proteases | Chloro_Bact_Ser_Proteases | Family | 37,880 | true | false | The peptidase S1C family consists of serine proteases that play a role in the degradation of abnormal exported proteins, propeptide processing, and maturation of native proteins. They are involved in stress resistance, including responses to heat shock, ethanol, puromycin, and NaCl, during active exponential growth. So... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43343"
] | [
"Chloro_Bact_Ser_Proteases"
] | [
37880
] | 1 | [
"EC",
"METACYC"
] | [
"3.4.21.-",
"PWY-7884"
] | [
"EC:3.4.21.-",
"METACYC:PWY-7884"
] | 2 | [
"1l1j",
"1y8t",
"2l97",
"2z9i",
"3qo6",
"4ic5",
"4ic6",
"5hm9",
"5hma",
"5y28",
"5y2d",
"5zvj",
"6ieo",
"6z05",
"7co2",
"7co3",
"7co5",
"7co7",
"7vyz",
"7vz0",
"7w21",
"7w22",
"7w23",
"7w24",
"7w25",
"7w4r",
"7w4s",
"7w4t",
"7w4u",
"7w4v",
"7w4w",
"7xs0"... | 33 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
711,
33598,
2751,
14,
806
] | 5 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
12,
10,
30
] | 3 | true | Family | Chloroplastic and Bacterial Serine Proteases | Chloroplastic and Bacterial Serine Proteases | Chloro_Bact_Ser_Proteases | 3 |
IPR051202 | 51,202 | Peptidase C40 | Peptidase_C40 | Family | 37,396 | true | false | The peptidase C40 family comprises enzymes with diverse cell wall remodeling activities. Members of this family are involved in processes such as peptidoglycan binding, cell wall expansion, and cell separation during vegetative growth. Some proteins within this family exhibit endopeptidase activity, cleaving specific p... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR47053"
] | [
"Peptidase_C40"
] | [
37396
] | 1 | [] | [] | [] | 0 | [
"2evr",
"2fg0",
"2hbw",
"3h41",
"3npf",
"3pvq",
"4fdy",
"4hpe",
"4r0k",
"6sqx",
"7cfl",
"8i2d",
"8i2f",
"8v3w",
"8wt3",
"8wt4",
"9ubf"
] | 17 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
22,
36526,
71,
186,
591
] | 5 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Family | Peptidase C40 | Peptidase C40 | Peptidase_C40 | 6 |
IPR051203 | 51,203 | Polysaccharide Synthase-Related Protein | Polysaccharide_Synthase-Rel | Family | 25,069 | true | false | This family of proteins is involved in the biosynthesis and modification of polysaccharides and related molecules. Members of this family exhibit a range of enzymatic activities, including the epimerization of UDP-galactose to UDP-glucose, which is a key step in the production of various polysaccharides. Some proteins ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43318"
] | [
"Polysaccharide_Synthase-Rel"
] | [
25069
] | 1 | [] | [] | [] | 0 | [
"2gn4",
"2gn6",
"2gn8",
"2gn9",
"2gna",
"3nkl",
"3pvz",
"3vvb",
"3vvc",
"3w1v",
"4g5h",
"4j2o",
"4tqg",
"5bju",
"5bjv",
"5bjw",
"5bjx",
"5bjy",
"6bwc"
] | 19 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
192,
24105,
45,
42,
685
] | 5 | [] | [] | 0 | true | Family | Polysaccharide Synthase-Related Protein | Polysaccharide Synthase-Related Protein | Polysaccharide_Synthase-Rel | 2 |
IPR051204 | 51,204 | ABC transporter permease/solute-binding domain-containing protein | ABC_transp_perm/SBD | Family | 31,505 | true | false | This family of proteins is involved in the transport of various osmoprotectants and nutrients across cellular membranes. They are part of ABC transporter complexes and are responsible for the translocation of substrates such as ergothioneine, a thiol antioxidant, as well as glycine betaine, carnitine, and choline, whic... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR30177"
] | [
"ABC_transp_perm/SBD"
] | [
31505
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"unclassified sequences"
] | [
31144,
12,
213,
136
] | 4 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Family | ABC transporter permease/solute-binding domain-containing protein | ABC transporter permease/solute-binding domain-containing protein | ABC_transp_perm/SBD | 7 |
IPR051205 | 51,205 | Ubiquinone biosynthesis monooxygenase UbiH/COQ6 | UbiH/COQ6_monooxygenase | Family | 28,513 | true | false | The UbiH/COQ6 family consists of FAD-dependent monooxygenases involved in ubiquinone biosynthesis, a vital component of the mitochondrial electron transport chain. Members of this family are responsible for various hydroxylation reactions on the aromatic ring of ubiquinone precursors, such as the hydroxylation of polyp... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43876"
] | [
"UbiH/COQ6_monooxygenase"
] | [
28513
] | 1 | [
"EC",
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"1.14.15.45",
"1.14.15.46",
"R-BTA-2142789",
"R-CEL-2142789",
"R-DDI-2142789",
"R-DME-2142789",
"R-DRE-2142789",
"R-HSA-2142789",
"R-MMU-2142789",
"R-RNO-2142789",
"R-SCE-2142789",
"R-SPO-2142789",
"R-XTR-2142789"
] | [
"EC:1.14.15.45",
"EC:1.14.15.46",
"REACTOME:R-BTA-2142789",
"REACTOME:R-CEL-2142789",
"REACTOME:R-DDI-2142789",
"REACTOME:R-DME-2142789",
"REACTOME:R-DRE-2142789",
"REACTOME:R-HSA-2142789",
"REACTOME:R-MMU-2142789",
"REACTOME:R-RNO-2142789",
"REACTOME:R-SCE-2142789",
"REACTOME:R-SPO-2142789",
... | 13 | [
"4k22",
"4n9x",
"7mwa"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
22732,
5519,
262
] | 3 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
9,
1,
4,
1,
3,
10,
4,
2,
4,
6,
1,
1,
11
] | 13 | true | Family | Ubiquinone biosynthesis monooxygenase UbiH/COQ6 | Ubiquinone biosynthesis monooxygenase UbiH/COQ6 | UbiH/COQ6_monooxygenase | 2 |
IPR051206 | 51,206 | N-acetylmuramoyl-L-alanine amidase 2 | NAMLAA_amidase_2 | Family | 26,001 | true | false | This family of proteins includes autolysins and amidases that play a crucial role in bacterial cell wall metabolism. They are involved in processes such as cell separation, cell-wall turnover, and peptidoglycan recycling. These enzymes specifically cleave the amide bond between the lactyl group of N-acetylmuramic acid ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR30417"
] | [
"NAMLAA_amidase_2"
] | [
26001
] | 1 | [
"EC",
"METACYC"
] | [
"3.5.1.28",
"PWY-7883"
] | [
"EC:3.5.1.28",
"METACYC:PWY-7883"
] | 2 | [
"1j3g",
"1yb0",
"2ar3",
"2bh7",
"2l47",
"2wkx",
"2y28",
"2y2b",
"2y2c",
"2y2d",
"2y2e",
"3d2y",
"3d2z",
"3hmb",
"3rdr",
"4bj4",
"4bol",
"4bpa",
"4bxd",
"4bxe",
"4bxj"
] | 21 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
45,
24896,
207,
641,
212
] | 5 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)"
] | [
1,
2
] | 2 | true | Family | N-acetylmuramoyl-L-alanine amidase 2 | N-acetylmuramoyl-L-alanine amidase 2 | NAMLAA_amidase_2 | 2 |
IPR051207 | 51,207 | Mitochondrial Complex I NDUFA9 Subunit | ComplexI_NDUFA9_subunit | Family | 26,878 | true | false | The NDUFA9 complex I subunit family comprises accessory subunits of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which are not directly involved in catalysis but are essential for proper assembly and function of Complex I. Complex I plays a crucial role in cellular energy production, tra... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12126"
] | [
"ComplexI_NDUFA9_subunit"
] | [
26878
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-611105",
"R-BTA-6799198",
"R-DDI-6799198",
"R-HSA-611105",
"R-HSA-6799198",
"R-MMU-611105",
"R-MMU-6799198",
"R-RNO-611105",
"R-RNO-6799198"
] | [
"REACTOME:R-BTA-611105",
"REACTOME:R-BTA-6799198",
"REACTOME:R-DDI-6799198",
"REACTOME:R-HSA-611105",
"REACTOME:R-HSA-6799198",
"REACTOME:R-MMU-611105",
"REACTOME:R-MMU-6799198",
"REACTOME:R-RNO-611105",
"REACTOME:R-RNO-6799198"
] | 9 | [
"5gpn",
"5gup",
"5lnk",
"5xtb",
"5xtd",
"5xth",
"5xti",
"6g2j",
"6g72",
"6gcs",
"6q9d",
"6qa9",
"6qbx",
"6qc2",
"6qc3",
"6qc4",
"6qc5",
"6qc6",
"6qc7",
"6qc8",
"6qc9",
"6qca",
"6qcf",
"6rfq",
"6rfr",
"6rfs",
"6x89",
"6y79",
"6yj4",
"6zk9",
"6zkc",
"6zkd"... | 263 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
896,
16703,
8967,
312
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
15,
1,
2,
4,
1,
6,
2,
2,
12,
3,
1,
1,
20
] | 13 | true | Family | Mitochondrial Complex I NDUFA9 Subunit | Mitochondrial Complex I NDUFA9 Subunit | ComplexI_NDUFA9_subunit | 9 |
IPR051208 | 51,208 | Class-I Fumarase/Tartrate Dehydratase | Class-I_Fumarase/Tartrate_DH | Family | 12,941 | true | false | The Class-I Fumarase Family comprises enzymes that catalyze the reversible hydration of fumarate to (S)-malate, a key step in the tricarboxylic acid (TCA) cycle for energy production in the form of NADH. Members function predominantly as aerobic enzymes, with some displaying D-tartrate dehydratase activity, although th... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR30389"
] | [
"Class-I_Fumarase/Tartrate_DH"
] | [
12941
] | 1 | [
"EC"
] | [
"4.2.1"
] | [
"EC:4.2.1"
] | 1 | [
"5l2r",
"6msn",
"6mso",
"6unz",
"6uo0",
"6uoi",
"6uoj",
"6up9",
"6upm",
"6upo",
"6uq8",
"6uq9",
"6uqb",
"6uql",
"6uqm",
"6uqn",
"7xky"
] | 17 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Siphoviridae sp. ctBLh2",
"unclassified sequences"
] | [
388,
11534,
620,
1,
398
] | 5 | [
"Escherichia coli (strain K12)"
] | [
3
] | 1 | true | Family | Class-I Fumarase/Tartrate Dehydratase | Class-I Fumarase/Tartrate Dehydratase | Class-I_Fumarase/Tartrate_DH | 4 |
IPR051210 | 51,210 | Ubiquitin ligases and GEF domain-containing protein | Ub_ligase/GEF_domain | Family | 22,018 | true | false | This family of proteins includes E3 ubiquitin-protein ligases and guanine nucleotide exchange factors (GEFs), which are involved in a variety of cellular processes. The E3 ubiquitin-protein ligases in this family are responsible for the ubiquitination of substrates, a post-translational modification that can lead to pr... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR22870"
] | [
"Ub_ligase/GEF_domain"
] | [
22018
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DDI-1169408",
"R-DDI-936440",
"R-DDI-983168",
"R-DDI-9909505"
] | [
"REACTOME:R-DDI-1169408",
"REACTOME:R-DDI-936440",
"REACTOME:R-DDI-983168",
"REACTOME:R-DDI-9909505"
] | 4 | [
"4d9s",
"4dnu",
"4dnv",
"4dnw",
"4naa",
"4nbm",
"4nc4",
"6dd7",
"7vgg",
"8gqe"
] | 10 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
12,
1558,
20312,
93,
43
] | 5 | [
"Arabidopsis thaliana",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
123,
2,
3,
4,
2,
61,
4,
167
] | 8 | true | Family | Ubiquitin ligases and GEF domain-containing protein | Ubiquitin ligases and GEF domain-containing protein | Ub_ligase/GEF_domain | 4 |
IPR051211 | 51,211 | Phosphatidylglycerol lysyltransferase | PG_lysyltransferase | Family | 10,738 | true | false | The LPG synthase family catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), resulting in the formation of lysylphosphatidylglycerol (LPG), which is a major component of the bacterial membrane with a positive net charge. The synthesis of LPG is crucial for bacteria... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR34697"
] | [
"PG_lysyltransferase"
] | [
10738
] | 1 | [
"EC"
] | [
"2.3.2.3"
] | [
"EC:2.3.2.3"
] | 1 | [
"4v34",
"4v35",
"4v36",
"5vrv",
"6lv0",
"6lvf",
"7duw",
"7f47",
"9goe",
"9j8q",
"9j8r",
"9j8s"
] | 12 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Stenosarchaea group",
"unclassified sequences"
] | [
10120,
507,
46,
65
] | 4 | [
"Arabidopsis thaliana"
] | [
1
] | 1 | true | Family | Phosphatidylglycerol lysyltransferase | Phosphatidylglycerol lysyltransferase | PG_lysyltransferase | 7 |
IPR051212 | 51,212 | Type I restriction enzyme S subunit | Type-I_RE_S_subunit | Family | 10,838 | true | false | Type I restriction enzyme specificity subunits (S subunits) are part of a multi-subunit enzyme complex involved in the recognition and modification of DNA. These subunits determine the DNA sequence specificity for the enzyme complex. Together with the modification (M) and restriction (R) subunits, they form a system th... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43140"
] | [
"Type-I_RE_S_subunit"
] | [
10838
] | 1 | [] | [] | [] | 0 | [
"2y7c",
"2y7h",
"3okg",
"5ybb",
"7bst",
"7bto",
"7btp",
"7btq",
"7btr",
"8w0p",
"8w2p",
"8w2q"
] | 12 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
188,
10497,
17,
8,
128
] | 5 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Type I restriction enzyme S subunit | Type I restriction enzyme S subunit | Type-I_RE_S_subunit | 9 |
IPR051213 | 51,213 | START domain-containing lipid transfer | START_lipid_transfer | Family | 17,650 | true | false | The START domain-containing protein family is involved in the non-vesicular intracellular trafficking and intermembrane transfer of specific lipids. Members of this family can recognize and shuttle various lipid species, including ceramides, diacylglycerol lipids, phosphatidylcholine, and phosphatidyethanolamine. The S... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR19308"
] | [
"START_lipid_transfer"
] | [
17650
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-1483191",
"R-BTA-1660661",
"R-BTA-77289",
"R-DRE-1660661",
"R-HSA-1483191",
"R-HSA-1660661",
"R-HSA-2142789",
"R-HSA-77289",
"R-HSA-9837999",
"R-MMU-1483191",
"R-MMU-2142789",
"R-MMU-77289",
"R-RNO-1483191",
"R-RNO-77289"
] | [
"REACTOME:R-BTA-1483191",
"REACTOME:R-BTA-1660661",
"REACTOME:R-BTA-77289",
"REACTOME:R-DRE-1660661",
"REACTOME:R-HSA-1483191",
"REACTOME:R-HSA-1660661",
"REACTOME:R-HSA-2142789",
"REACTOME:R-HSA-77289",
"REACTOME:R-HSA-9837999",
"REACTOME:R-MMU-1483191",
"REACTOME:R-MMU-2142789",
"REACTOME:R-... | 14 | [
"1ln1",
"1ln2",
"1ln3",
"2e3m",
"2e3n",
"2e3o",
"2e3p",
"2e3q",
"2e3r",
"2e3s",
"2z9y",
"2z9z",
"3fo5",
"3h3q",
"3h3r",
"3h3s",
"3h3t",
"3qsz",
"5jjd",
"5zyg",
"5zyh",
"5zyi",
"5zyj",
"5zyk",
"5zyl",
"5zym",
"6iez",
"6if0",
"6j0o",
"6j81",
"6ser",
"6vvq"... | 33 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
2056,
15562,
9,
23
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
43,
4,
12,
3,
34,
20,
1,
16,
19,
56
] | 10 | true | Family | START domain-containing lipid transfer | START domain-containing lipid transfer | START_lipid_transfer | 3 |
IPR051215 | 51,215 | Glycyl Radical Enzyme | GRE | Family | 7,684 | true | false | This family of proteins includes enzymes that perform radical-mediated chemical reactions, typically involving the cleavage or formation of carbon-based bonds in various substrates. Members of this family are characterized by the presence of a glycyl radical that is essential for their catalytic activity. The enzymes a... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43641"
] | [
"GRE"
] | [
7684
] | 1 | [] | [] | [] | 0 | [
"1r8w",
"1r9d",
"2f3o",
"2y8n",
"2yaj",
"4mtj",
"4pkc",
"4pkf",
"5a0u",
"5a0z",
"5bwd",
"5bwe",
"5fau",
"5fav",
"5faw",
"5fay",
"5i2a",
"5i2g",
"5kdp",
"5ymr",
"6lon",
"6nd3",
"6vue",
"6vxc",
"6vxe",
"6xs4",
"7e7l",
"7kq3",
"7kq4",
"7vua",
"8id0",
"8id1"... | 45 | [] | [] | [] | [] | 0 | [] | [
"IPR050012",
"IPR053798"
] | 0 | 2 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
39,
6861,
119,
665
] | 4 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Family | Glycyl Radical Enzyme | Glycyl Radical Enzyme | GRE | 2 |
IPR051216 | 51,216 | Teneurin | Teneurin | Family | 13,780 | true | true | Teneurins are a family of phylogenetically conserved transmembrane glycoproteins expressed during pattern formation and morphogenesis [ ]. Originally discovered as ten-m and ten-a in Drosophila melanogaster, the teneurin family is conserved from Caenorhabditis elegans (ten-1) to vertebrates, in which four paralogs exis... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR11219"
] | [
"Teneurin_domain"
] | [
13780
] | 1 | [] | [] | [] | 0 | [
"2vj2",
"4xlw",
"6cmx",
"6fay",
"6fb3",
"6ska",
"6ske",
"6vhh",
"7alt",
"7bam",
"7ban",
"7bao",
"7plp",
"8fia",
"8r50",
"8r51",
"8r54"
] | 17 | [
"PUB00009650",
"PUB00012632",
"PUB00014529",
"PUB00014530",
"PUB00014531",
"PUB00043665",
"PUB00043666",
"PUB00043667",
"PUB00066375",
"PUB00066378",
"PUB00155423",
"PUB00155629",
"PUB00155630"
] | [
"10341219",
"12783990",
"11146505",
"12361962",
"10588872",
"16406038",
"17095284",
"17502993",
"23028443",
"21724987",
"29540701",
"29414938",
"25406022"
] | [
"Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain.",
"The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription.",
"Teneurin-2 is expressed in tissues that regulate limb and... | [
1999,
2003,
2001,
2002,
1999,
2006,
2007,
2007,
2012,
2011,
2018,
2018,
2015
] | 13 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
297,
13474,
9
] | 3 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
6,
146,
8,
30,
18,
36
] | 6 | true | Family | Teneurin | Teneurin | Teneurin | 7 |
IPR051217 | 51,217 | Insect Cuticle Structural | Insect_Cuticle_Struc_Prot | Family | 15,993 | true | false | The Cuticle Protein family comprises structural proteins that are integral components of the protective cuticle layer in various insect species. These proteins play a crucial role in determining the physical properties of the cuticle, such as stiffness, elasticity, and resilience, which are essential for insect surviva... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12236"
] | [
"Insect_Cuticle_Struc_Prot"
] | [
15993
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
4,
15989
] | 2 | [
"Drosophila melanogaster"
] | [
72
] | 1 | true | Family | Insect Cuticle Structural | Insect Cuticle Structural | Insect_Cuticle_Struc_Prot | 6 |
IPR051218 | 51,218 | Secreted Mono/Diacylglycerol Lipase | Sec_MonoDiacylglyc_Lipase | Family | 12,795 | true | false | The lipase family, part of the AB hydrolase superfamily, encompasses secreted enzymes predominantly involved in the hydrolysis of mono- and diacylglycerols. Members of this family exhibit a strong preference for cleaving ester bonds at the 1,3-positions of glycerides, releasing free fatty acids, particularly oleic acid... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR45856"
] | [
"Sec_MonoDiacylglyc_Lipase"
] | [
12795
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"... | [
"3.1.1.-",
"PWY-1921",
"PWY-5835",
"PWY-6190",
"PWY-6308",
"PWY-6322",
"PWY-6339",
"PWY-6415",
"PWY-6558",
"PWY-6848",
"PWY-7002",
"PWY-7352",
"PWY-7367",
"PWY-7521",
"PWY-7599",
"PWY-7660",
"PWY-7712",
"PWY-7713",
"PWY-7730",
"PWY-7769",
"PWY-7982",
"PWY-8058",
"PWY-8143... | [
"EC:3.1.1.-",
"METACYC:PWY-1921",
"METACYC:PWY-5835",
"METACYC:PWY-6190",
"METACYC:PWY-6308",
"METACYC:PWY-6322",
"METACYC:PWY-6339",
"METACYC:PWY-6415",
"METACYC:PWY-6558",
"METACYC:PWY-6848",
"METACYC:PWY-7002",
"METACYC:PWY-7352",
"METACYC:PWY-7367",
"METACYC:PWY-7521",
"METACYC:PWY-7... | 28 | [
"1lgy",
"1tgl",
"1tic",
"2ory",
"3ngm",
"3tgl",
"3uue",
"3uuf",
"4tgl",
"4zrd",
"4zre",
"5gw8",
"5tgl",
"6a0w",
"6qpp",
"6qpr",
"7spr"
] | 17 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
2,
3848,
8776,
37,
132
] | 5 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
12,
2,
13,
41
] | 4 | true | Family | Secreted Mono/Diacylglycerol Lipase | Secreted Mono/Diacylglycerol Lipase | Sec_MonoDiacylglyc_Lipase | 4 |
IPR051219 | 51,219 | Heterochromatin-associated chromo domain-containing protein | Heterochromatin_chromo-domain | Family | 14,304 | true | true | This family of proteins is involved in the formation and maintenance of heterochromatin, a tightly packed form of DNA associated with gene repression. Members of this family recognise and bind to specific methylated lysine residues on histone H3 tails, particularly 'Lys-9', which is a hallmark of heterochromatin [ , ].... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR22812"
] | [
"Heterochromatin_chromo-domain"
] | [
14304
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-73772",
"R-CEL-983231",
"R-HSA-427389",
"R-HSA-4551638",
"R-HSA-73772",
"R-HSA-8953750",
"R-HSA-9609690",
"R-HSA-983231",
"R-HSA-9843940",
"R-MMU-8953750",
"R-MMU-983231",
"R-SPO-73772",
"R-SPO-983231"
] | [
"REACTOME:R-CEL-73772",
"REACTOME:R-CEL-983231",
"REACTOME:R-HSA-427389",
"REACTOME:R-HSA-4551638",
"REACTOME:R-HSA-73772",
"REACTOME:R-HSA-8953750",
"REACTOME:R-HSA-9609690",
"REACTOME:R-HSA-983231",
"REACTOME:R-HSA-9843940",
"REACTOME:R-MMU-8953750",
"REACTOME:R-MMU-983231",
"REACTOME:R-SPO-... | 13 | [
"1ap0",
"1dz1",
"1g6z",
"1guw",
"1kna",
"1kne",
"1q3l",
"1s4z",
"2dnt",
"2fmm",
"2l11",
"2m2l",
"2mj8",
"2rsn",
"2rso",
"2rvl",
"2rvm",
"2rvn",
"3dm1",
"3f2u",
"3fdt",
"3g7l",
"3i3c",
"3kup",
"3lwe",
"3q6s",
"3qo2",
"3r93",
"3svm",
"3tzd",
"4hae",
"4quc"... | 62 | [
"PUB00045061",
"PUB00088108",
"PUB00145416",
"PUB00155079",
"PUB00155080",
"PUB00155081",
"PUB00155082"
] | [
"15607976",
"28167679",
"10835380",
"19783980",
"19732946",
"36193674",
"22083954"
] | [
"Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.",
"Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage.",
"Four chromo-domain proteins of Schizosaccharomyces pombe differentially repress transcription at various chromosomal l... | [
2004,
2017,
2000,
2009,
2009,
2022,
2012
] | 7 | [] | [] | 0 | 0 | null | [
"Cladosporium fulvum T-1 virus",
"Eukaryota",
"Thalassoglobus polymorphus",
"metagenomes"
] | [
1,
14300,
1,
2
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
5,
16,
32,
17,
14,
4,
13,
3
] | 8 | true | Family | Heterochromatin-associated chromo domain-containing protein | Heterochromatin-associated chromo domain-containing protein | Heterochromatin_chromo-domain | 1 |
IPR051220 | 51,220 | Tail Fiber Assembly Chaperone | TFA_Chaperone | Family | 10,536 | true | false | This family of proteins includes chaperones that are involved in the assembly of tail fibers in bacteriophages. These proteins act catalytically to form tail protein dimers and remain associated with the tail fiber, participating in host receptor binding. The assembly of tail fibers is crucial for the bacteriophages to... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR34413"
] | [
"TFA_Chaperone"
] | [
10536
] | 1 | [] | [] | [] | 0 | [
"5yvq"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
10245,
24,
252,
15
] | 4 | [
"Escherichia coli (strain K12)",
"Mus musculus"
] | [
7,
1
] | 2 | true | Family | Tail Fiber Assembly Chaperone | Tail Fiber Assembly Chaperone | TFA_Chaperone | 5 |
IPR051221 | 51,221 | Low-density lipoprotein receptor-related | LDLR-related | Family | 23,528 | true | false | This family of proteins is involved in receptor-mediated endocytosis and internalization of various ligands, including lipoproteins, vitamins, hormones, and proteins. Members of this family play crucial roles in cellular lipid homeostasis, embryonic development, and the clearance of apoptotic cells. They are also impli... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR22722"
] | [
"LDLR-related"
] | [
23528
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-8856825",
"R-BTA-8856828",
"R-BTA-8964026",
"R-BTA-8964038",
"R-DME-9758890",
"R-GGA-8866376",
"R-GGA-8866427",
"R-HSA-196791",
"R-HSA-2168880",
"R-HSA-3000178",
"R-HSA-432142",
"R-HSA-8856825",
"R-HSA-8856828",
"R-HSA-8866376",
"R-HSA-8866427",
"R-HSA-8964026",
"R-HSA-8964038... | [
"REACTOME:R-BTA-8856825",
"REACTOME:R-BTA-8856828",
"REACTOME:R-BTA-8964026",
"REACTOME:R-BTA-8964038",
"REACTOME:R-DME-9758890",
"REACTOME:R-GGA-8866376",
"REACTOME:R-GGA-8866427",
"REACTOME:R-HSA-196791",
"REACTOME:R-HSA-2168880",
"REACTOME:R-HSA-3000178",
"REACTOME:R-HSA-432142",
"REACTOME:... | 42 | [
"1cr8",
"1j8e",
"1n7d",
"1xfe",
"2fcw",
"2fyj",
"2fyl",
"2i1p",
"2lgp",
"2m0p",
"3m0c",
"3p5c",
"3v65",
"4zrp",
"4zrq",
"5b4x",
"5b4y",
"6byv",
"7ffn",
"7qbd",
"7qbe",
"7qbf",
"7qbg",
"8em4",
"8em7",
"8jut",
"8juu",
"8jx8",
"8jx9",
"8jxa",
"8jxb",
"8jxc"... | 55 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadati",
"uncultured organism MedDCM-OCT-S01-C5"
] | [
23518,
9,
1
] | 3 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
13,
65,
28,
73,
42,
38
] | 6 | true | Family | Low-density lipoprotein receptor-related | Low-density lipoprotein receptor-related | LDLR-related | 3 |
IPR051222 | 51,222 | Pentatricopeptide/CCM1 RNA-binding | PPR/CCM1_RNA-binding | Family | 8,727 | true | false | The PPR family proteins are characterized by their pentatricopeptide repeat motifs, which are involved in various aspects of RNA metabolism within organelles. Members of the PPR family, specifically the P subfamily, are typically localized to mitochondria or chloroplasts and play crucial roles in processes such as RNA ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR47942"
] | [
"PPR/CCM1_RNA-binding"
] | [
8727
] | 1 | [] | [] | [] | 0 | [
"6een"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"marine sediment metagenome"
] | [
8,
8718,
1
] | 3 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
47,
38,
31
] | 3 | true | Family | Pentatricopeptide/CCM1 RNA-binding | Pentatricopeptide/CCM1 RNA-binding | PPR/CCM1_RNA-binding | 6 |
IPR051223 | 51,223 | Polycystin | Polycystin | Family | 13,048 | true | false | The Polycystin family is involved in various functions related to calcium signaling and mechanosensation. Members of this family form heteromeric and homomeric ion channels that are permeable to cations, particularly calcium. These channels play roles in processes such as fluid-flow mechanosensation in renal epithelium... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR10877"
] | [
"Polycystin"
] | [
13048
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-5620916",
"R-CEL-5620916",
"R-DRE-5620916",
"R-HSA-5620916",
"R-MMU-5620916"
] | [
"REACTOME:R-BTA-5620916",
"REACTOME:R-CEL-5620916",
"REACTOME:R-DRE-5620916",
"REACTOME:R-HSA-5620916",
"REACTOME:R-MMU-5620916"
] | 5 | [
"5k47",
"5mke",
"5mkf",
"5t4d",
"5z1w",
"6a70",
"6d1w",
"6du8",
"6t9n",
"6t9o",
"6wb8",
"7d7e",
"7d7f",
"8hk7",
"8k3s",
"8z6b",
"8z6f",
"8z6h",
"8zkh",
"8zkr",
"8zks",
"8zkt",
"8zku",
"9dli",
"9dwq"
] | 25 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
6,
13038,
4
] | 3 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
24,
18,
15,
14,
13
] | 6 | true | Family | Polycystin | Polycystin | Polycystin | 3 |
IPR051225 | 51,225 | NAD(P)-dependent epimerase/dehydratase | NAD(P)_epim/dehydratase | Family | 6,898 | true | false | The NAD(P)-dependent epimerase/dehydratase family is characterized by enzymes that utilize NAD(+) or NADP(+) as cofactors to catalyze the epimerization or dehydration of various substrates. Members of this family are involved in diverse metabolic pathways, including the catabolism of amino acids such as L-threonine. Th... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR42687"
] | [
"NAD(P)_epim/dehydratase"
] | [
6898
] | 1 | [] | [] | [] | 0 | [
"2yy7",
"3a1n",
"3a4v",
"3a9w",
"3ajr",
"3wmw",
"3wmx",
"4yr9",
"4yra",
"4yrb",
"5k4q",
"5k4t",
"5k4u",
"5k4v",
"5k4w",
"5k4y",
"5k50",
"5l9a",
"5lc1",
"5y1d",
"5y1e",
"5y1f",
"5y1g",
"5z75",
"5z76",
"6jyg",
"7cgv",
"7epr",
"7eps",
"7ol1",
"8gil",
"8gjb"... | 32 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
66,
4469,
2247,
116
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
3,
1,
2,
4,
2
] | 6 | true | Family | NAD(P)-dependent epimerase/dehydratase | NAD(P)-dependent epimerase/dehydratase | NAD(P)_epim/dehydratase | 6 |
IPR051226 | 51,226 | Protein Phosphatase 1 Regulatory Subunit | PP1_Regulatory_Subunit | Family | 11,566 | true | false | The protein family is involved in the regulation of protein phosphatase 1 (PP1) activity, which is central to various cellular processes. Members of this family mediate the binding to myosin and regulate myosin phosphatase activity, influencing muscle contraction and cell motility. Some members are involved in the deph... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR24179"
] | [
"PP1_Regulatory_Subunit"
] | [
11566
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DRE-2565942",
"R-DRE-5625740",
"R-GGA-2565942",
"R-GGA-5627123",
"R-HSA-2565942",
"R-HSA-5625740",
"R-HSA-5625900",
"R-HSA-5627117",
"R-HSA-5627123",
"R-MMU-2565942",
"R-MMU-5625740",
"R-MMU-5627123",
"R-RNO-2565942",
"R-RNO-5625740",
"R-RNO-5627123"
] | [
"REACTOME:R-DRE-2565942",
"REACTOME:R-DRE-5625740",
"REACTOME:R-GGA-2565942",
"REACTOME:R-GGA-5627123",
"REACTOME:R-HSA-2565942",
"REACTOME:R-HSA-5625740",
"REACTOME:R-HSA-5625900",
"REACTOME:R-HSA-5627117",
"REACTOME:R-HSA-5627123",
"REACTOME:R-MMU-2565942",
"REACTOME:R-MMU-5625740",
"REACTOM... | 15 | [
"1s70",
"2kjy",
"6py8"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
14,
11552
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
6,
40,
24,
25,
19,
27
] | 6 | true | Family | Protein Phosphatase 1 Regulatory Subunit | Protein Phosphatase 1 Regulatory Subunit | PP1_Regulatory_Subunit | 1 |
IPR051227 | 51,227 | Chondroitin sulfate glycosyltransferase | CS_glycosyltransferase | Family | 10,899 | true | false | This family of proteins is involved in the biosynthesis of chondroitin sulfate, a key component of the extracellular matrix in cartilage. Members of this family exhibit glycosyltransferase activity, transferring glucuronic acid and N-acetylgalactosamine from their respective UDP-sugar donors to the growing chondroitin ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12369"
] | [
"CS_glycosyltransferase"
] | [
10899
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.4.1",
"R-HSA-2022870",
"R-HSA-3595177",
"R-MMU-2022870"
] | [
"EC:2.4.1",
"REACTOME:R-HSA-2022870",
"REACTOME:R-HSA-3595177",
"REACTOME:R-MMU-2022870"
] | 4 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"viral metagenome"
] | [
10897,
2
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
21,
5,
29,
23,
20
] | 6 | true | Family | Chondroitin sulfate glycosyltransferase | Chondroitin sulfate glycosyltransferase | CS_glycosyltransferase | 6 |
IPR051229 | 51,229 | ALYREF mRNA export adapter | ALYREF_mRNA_export | Family | 10,657 | true | false | The ALYREF family proteins function as export adapters involved in the nuclear export of both spliced and unspliced mRNA, playing a crucial role in mRNA processing and cytoplasmic trafficking. They are components of the TREX complex, which links transcription, splicing, and mRNA export. ALYREF family members bind to mR... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR19965"
] | [
"ALYREF_mRNA_export"
] | [
10657
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-159227",
"R-BTA-159230",
"R-BTA-159231",
"R-BTA-159236",
"R-BTA-72163",
"R-BTA-72187",
"R-BTA-73856",
"R-HSA-159227",
"R-HSA-159230",
"R-HSA-159231",
"R-HSA-159236",
"R-HSA-72163",
"R-HSA-72187",
"R-HSA-73856",
"R-MMU-159227",
"R-MMU-159230",
"R-MMU-159231",
"R-MMU-159236",
... | [
"REACTOME:R-BTA-159227",
"REACTOME:R-BTA-159230",
"REACTOME:R-BTA-159231",
"REACTOME:R-BTA-159236",
"REACTOME:R-BTA-72163",
"REACTOME:R-BTA-72187",
"REACTOME:R-BTA-73856",
"REACTOME:R-HSA-159227",
"REACTOME:R-HSA-159230",
"REACTOME:R-HSA-159231",
"REACTOME:R-HSA-159236",
"REACTOME:R-HSA-72163"... | 27 | [
"1no8",
"2f3j",
"2kt5",
"2yka",
"3ulh",
"7znk",
"8r7l",
"8srr"
] | 8 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
10657
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
23,
4,
5,
8,
7,
20,
2,
23,
9,
1,
2,
32
] | 12 | true | Family | ALYREF mRNA export adapter | ALYREF mRNA export adapter | ALYREF_mRNA_export | 9 |
IPR051230 | 51,230 | Amyloid-beta A4 Precursor Protein-Binding | APP-Binding | Family | 9,060 | true | false | The Amyloid-beta A4 precursor protein-binding family is involved in synaptic vesicle exocytosis and modulation of amyloid-beta precursor protein (APP) processing, potentially affecting APP-beta formation. Members of the family interact with essential components of the synaptic vesicle exocytotic machinery, such as STXB... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR12345"
] | [
"APP-Binding"
] | [
9060
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-212676",
"R-HSA-212676",
"R-HSA-3928664",
"R-HSA-447043",
"R-HSA-5213460",
"R-HSA-5675482",
"R-HSA-6794361",
"R-HSA-6798695",
"R-HSA-9609736",
"R-MMU-212676",
"R-MMU-3928664",
"R-MMU-447043",
"R-MMU-5213460",
"R-MMU-5675482",
"R-MMU-6798695",
"R-RNO-212676",
"R-RNO-3928664",
... | [
"REACTOME:R-CEL-212676",
"REACTOME:R-HSA-212676",
"REACTOME:R-HSA-3928664",
"REACTOME:R-HSA-447043",
"REACTOME:R-HSA-5213460",
"REACTOME:R-HSA-5675482",
"REACTOME:R-HSA-6794361",
"REACTOME:R-HSA-6798695",
"REACTOME:R-HSA-9609736",
"REACTOME:R-MMU-212676",
"REACTOME:R-MMU-3928664",
"REACTOME:R-... | 21 | [
"1aqc",
"1n99",
"1nte",
"1obx",
"1oby",
"1obz",
"1r6j",
"1u37",
"1u38",
"1u39",
"1u3b",
"1v1t",
"1w9e",
"1w9o",
"1w9q",
"1x11",
"1x45",
"1y7n",
"1ybo",
"2yt7",
"2yt8",
"3suz",
"3sv1",
"4dbb",
"4z33",
"5a2p",
"5g1d",
"5g1e",
"6ak2",
"6kmh",
"6r9h",
"6rlc"... | 76 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"viral metagenome"
] | [
9059,
1
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
36,
14,
16,
28,
23
] | 6 | true | Family | Amyloid-beta A4 Precursor Protein-Binding | Amyloid-beta A4 Precursor Protein-Binding | APP-Binding | 6 |
IPR051231 | 51,231 | SOSS complex subunit B | SOSS-B | Family | 4,828 | true | false | The SOSS-B family is involved in the cellular DNA damage response, particularly in promoting DNA repair and the G2/M checkpoint. Members of the family function as components of the SOSS complex, which operates downstream of the MRN complex. They act as sensors of single-stranded DNA, with a preference for polypyrimidin... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR13356"
] | [
"SOSS-B"
] | [
4828
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-6807505",
"R-DDI-6807505",
"R-DME-6807505",
"R-DRE-6807505",
"R-HSA-6807505",
"R-MMU-6807505",
"R-RNO-6807505",
"R-XTR-6807505"
] | [
"REACTOME:R-BTA-6807505",
"REACTOME:R-DDI-6807505",
"REACTOME:R-DME-6807505",
"REACTOME:R-DRE-6807505",
"REACTOME:R-HSA-6807505",
"REACTOME:R-MMU-6807505",
"REACTOME:R-RNO-6807505",
"REACTOME:R-XTR-6807505"
] | 8 | [
"1o7i",
"2mna",
"4owt",
"4oww",
"4owx",
"5d8e",
"5d8f",
"7wcg",
"8aa9",
"8aaj",
"8aas",
"8c5z",
"8oej",
"8oel",
"8rbz"
] | 15 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
1876,
3,
2882,
67
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
2,
2,
9,
1,
5,
9,
5,
9,
5
] | 9 | true | Family | SOSS complex subunit B | SOSS complex subunit B | SOSS-B | 7 |
IPR051232 | 51,232 | AT-rich Interactive Domain/SWI1 Chromatin Remodeling | ARID/SWI1_ChromRemod | Family | 8,477 | true | false | The ARID/SWI1 protein family includes transcriptional regulators with diverse roles in gene expression, chromatin remodeling, and developmental processes. Members of the family bind to AT-rich DNA regions and can act as transcription coactivators or repressors. They are involved in adipogenesis, liver development, sper... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR13964"
] | [
"ARID/SWI1_ChromRemod"
] | [
8477
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-3214815",
"R-HSA-3214842",
"R-HSA-427413",
"R-HSA-9679191",
"R-MMU-3214815",
"R-MMU-3214842",
"R-RNO-3214815",
"R-SCE-3214815",
"R-SPO-3214815",
"R-SPO-3214842"
] | [
"REACTOME:R-HSA-3214815",
"REACTOME:R-HSA-3214842",
"REACTOME:R-HSA-427413",
"REACTOME:R-HSA-9679191",
"REACTOME:R-MMU-3214815",
"REACTOME:R-MMU-3214842",
"REACTOME:R-RNO-3214815",
"REACTOME:R-SCE-3214815",
"REACTOME:R-SPO-3214815",
"REACTOME:R-SPO-3214842"
] | 10 | [
"1ig6",
"1kkx",
"1kn5",
"2eqy",
"2lcc",
"2li6",
"2lm1",
"2mam",
"2oeh",
"2yrv",
"6bph",
"6l87",
"6uxv",
"6uxw",
"7c4j",
"7dm4",
"7egm",
"7egp",
"7v8n"
] | 19 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Lactobacillales"
] | [
8475,
2
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strai... | [
1,
20,
3,
18,
22,
1,
18,
1,
1
] | 9 | true | Family | AT-rich Interactive Domain/SWI1 Chromatin Remodeling | AT-rich Interactive Domain/SWI1 Chromatin Remodeling | ARID/SWI1_ChromRemod | 7 |
IPR051233 | 51,233 | Desulfoferrodoxin superoxide reductase | Desulfoferrodoxin_SOR | Family | 2,914 | true | false | The desulfoferrodoxin family comprises proteins that play a crucial role in the detoxification of reactive oxygen species, particularly the superoxide anion radical. Members of this family are characterized by their ability to catalyze the one-electron reduction of superoxide to hydrogen peroxide. This activity is esse... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR36541"
] | [
"Desulfoferrodoxin_SOR"
] | [
2914
] | 1 | [
"EC"
] | [
"1.15.1.2"
] | [
"EC:1.15.1.2"
] | 1 | [
"1dfx",
"1do6",
"1dqi",
"1dqk",
"1vzg",
"1vzh",
"1vzi",
"1y07",
"2amu",
"2hvb",
"2ji1",
"2ji2",
"2ji3",
"3qzb",
"4bff",
"4bfj",
"4bfk",
"4bgl",
"4bk8",
"4brj",
"4brv",
"4c4b",
"4c4u",
"4d7p",
"6gq8"
] | 25 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
349,
2355,
70,
140
] | 4 | [] | [] | 0 | true | Family | Desulfoferrodoxin superoxide reductase | Desulfoferrodoxin superoxide reductase | Desulfoferrodoxin_SOR | 8 |
IPR051234 | 51,234 | TAO Serine/Threonine-Protein Kinase | TAO_STE20_kinase | Family | 7,410 | true | false | The TAO kinase family is involved in various cellular processes, including the regulation of the p38/MAPK14 and MAPK8/JNK stress-activated MAPK cascades, DNA damage response, and cytoskeleton stability. Members of the family function as serine/threonine-protein kinases that activate MAPK cascades by phosphorylating ups... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR47167"
] | [
"TAO_STE20_kinase"
] | [
7410
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
... | [
"2.7.11.1",
"R-CEL-9013149",
"R-CEL-9013404",
"R-CEL-9013423",
"R-HSA-141444",
"R-HSA-2467813",
"R-HSA-2500257",
"R-HSA-5663220",
"R-HSA-68877",
"R-HSA-9013149",
"R-HSA-9013404",
"R-HSA-9013423",
"R-HSA-9648025",
"R-MMU-141444",
"R-MMU-2467813",
"R-MMU-2500257",
"R-MMU-5663220",
"R... | [
"EC:2.7.11.1",
"REACTOME:R-CEL-9013149",
"REACTOME:R-CEL-9013404",
"REACTOME:R-CEL-9013423",
"REACTOME:R-HSA-141444",
"REACTOME:R-HSA-2467813",
"REACTOME:R-HSA-2500257",
"REACTOME:R-HSA-5663220",
"REACTOME:R-HSA-68877",
"REACTOME:R-HSA-9013149",
"REACTOME:R-HSA-9013404",
"REACTOME:R-HSA-901342... | 30 | [
"1u5q",
"1u5r",
"2gcd",
"6bdn"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
7410
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
21,
6,
21,
12,
15
] | 6 | true | Family | TAO Serine/Threonine-Protein Kinase | TAO Serine/Threonine-Protein Kinase | TAO_STE20_kinase | 3 |
IPR051235 | 51,235 | Centrosomal Protein 152/SHC-Transforming Protein | CEP152/SHC-Transforming | Family | 6,643 | true | false | The CEP152 family is involved in centrosome duplication and centriole formation. Members act as molecular scaffolds, facilitating interactions between key molecules such as PLK4 and CENPJ. They are essential for recruiting CDK2, which is required for centriole duplication. The family also plays a significant role in de... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR10337"
] | [
"CEP152/SHC-Transforming"
] | [
6643
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-1250196",
"R-BTA-1250347",
"R-BTA-167044",
"R-BTA-180336",
"R-BTA-201556",
"R-BTA-210993",
"R-BTA-2424491",
"R-BTA-2428933",
"R-BTA-2730905",
"R-BTA-2871796",
"R-BTA-2871809",
"R-BTA-354192",
"R-BTA-512988",
"R-BTA-5654688",
"R-BTA-5654699",
"R-BTA-5654704",
"R-BTA-5654719",
... | [
"REACTOME:R-BTA-1250196",
"REACTOME:R-BTA-1250347",
"REACTOME:R-BTA-167044",
"REACTOME:R-BTA-180336",
"REACTOME:R-BTA-201556",
"REACTOME:R-BTA-210993",
"REACTOME:R-BTA-2424491",
"REACTOME:R-BTA-2428933",
"REACTOME:R-BTA-2730905",
"REACTOME:R-BTA-2871796",
"REACTOME:R-BTA-2871809",
"REACTOME:R-... | 147 | [
"1mil",
"1n3h",
"1oy2",
"1shc",
"1tce",
"2l1c",
"4n7v",
"4xwx",
"6csu",
"6csv"
] | 10 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Phocaeicola dorei",
"bird metagenome"
] | [
6641,
1,
1
] | 3 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
29,
3,
27,
14,
23
] | 5 | true | Family | Centrosomal Protein 152/SHC-Transforming Protein | Centrosomal Protein 152/SHC-Transforming Protein | CEP152/SHC-Transforming | 8 |
IPR051236 | 51,236 | Histone acetyltransferase RTT109-like | HAT_RTT109-like | Family | 5,795 | true | false | This family of proteins includes histone acetyltransferases, such as RTT109, which are known to acetylate lysine residues on histone H3. This modification plays a crucial role in nucleosome assembly, genomic stability, DNA repair, and transcriptional regulation during the S-phase of the cell cycle. The acetylation of s... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR31571"
] | [
"HAT_RTT109-like"
] | [
5795
] | 1 | [] | [] | [] | 0 | [
"2rim",
"2zfn",
"3cz7",
"3q33",
"3q35",
"3q66",
"3q68",
"3qm0",
"5zb9",
"5zba",
"5zbb",
"6o22",
"7bwz",
"7bx0",
"7bx1",
"7bxw",
"7c3o",
"8gq3",
"8gq4"
] | 19 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1170,
4616,
9
] | 3 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
2,
1
] | 3 | true | Family | Histone acetyltransferase RTT109-like | Histone acetyltransferase RTT109-like | HAT_RTT109-like | 3 |
IPR051238 | 51,238 | GDSL esterase/lipase | GDSL_esterase/lipase | Family | 9,578 | true | false | This family of proteins includes enzymes with esterase and lipase activities, characterized by the presence of a GDSL motif. These enzymes are involved in a variety of biological processes, including lipid metabolism and plant defense mechanisms. One member is specifically implicated in systemic acquired resistance and... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR45650"
] | [
"GDSL_esterase/lipase"
] | [
9578
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"... | [
"3.1.1.-",
"PWY-1921",
"PWY-5835",
"PWY-6190",
"PWY-6308",
"PWY-6322",
"PWY-6339",
"PWY-6415",
"PWY-6558",
"PWY-6848",
"PWY-7002",
"PWY-7352",
"PWY-7367",
"PWY-7521",
"PWY-7599",
"PWY-7660",
"PWY-7712",
"PWY-7713",
"PWY-7730",
"PWY-7769",
"PWY-7982",
"PWY-8058",
"PWY-8143... | [
"EC:3.1.1.-",
"METACYC:PWY-1921",
"METACYC:PWY-5835",
"METACYC:PWY-6190",
"METACYC:PWY-6308",
"METACYC:PWY-6322",
"METACYC:PWY-6339",
"METACYC:PWY-6415",
"METACYC:PWY-6558",
"METACYC:PWY-6848",
"METACYC:PWY-7002",
"METACYC:PWY-7352",
"METACYC:PWY-7367",
"METACYC:PWY-7521",
"METACYC:PWY-7... | 28 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Francisella salina"
] | [
9577,
1
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
82,
36,
46
] | 3 | true | Family | GDSL esterase/lipase | GDSL esterase/lipase | GDSL_esterase/lipase | 3 |
IPR051239 | 51,239 | 2'-Deoxynucleoside 5'-phosphate N-hydrolase | 2'-dNMP_N-hydrolase | Family | 3,771 | true | false | This family of proteins is involved in a nucleotide salvage pathway that processes epigenetically modified nucleotides to prevent their incorporation into DNA. Specifically, these enzymes catalyze the hydrolysis of the N-glycosidic bond in 5-hydroxymethyl-dUMP (hmdUMP), a cytotoxic nucleotide, converting it into non-to... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR15364"
] | [
"2'-dNMP_N-hydrolase"
] | [
3771
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"3.2.2.-",
"PWY-2681",
"PWY-5316",
"PWY-5381",
"PWY-7342",
"PWY-7564",
"PWY-8106",
"R-DRE-74259",
"R-HSA-74259",
"R-MMU-74259",
"R-RNO-74259"
] | [
"EC:3.2.2.-",
"METACYC:PWY-2681",
"METACYC:PWY-5316",
"METACYC:PWY-5381",
"METACYC:PWY-7342",
"METACYC:PWY-7564",
"METACYC:PWY-8106",
"REACTOME:R-DRE-74259",
"REACTOME:R-HSA-74259",
"REACTOME:R-MMU-74259",
"REACTOME:R-RNO-74259"
] | 11 | [
"2a0k",
"2f2t",
"2f62",
"2f64",
"2f67",
"2khz",
"2klh",
"4fyh",
"4fyi",
"4fyk",
"4kxl",
"4kxm",
"4kxn",
"4p5d",
"4p5e",
"6qai",
"7m5h",
"7o62",
"8os9",
"8osc",
"8pqp",
"8pqq",
"8pqr",
"8pqs",
"8pqt",
"8qc0",
"8qhq",
"8qhr",
"8rh3",
"8rps",
"8rpt",
"8rqd"... | 47 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"metagenomes"
] | [
241,
2780,
21,
684,
45
] | 5 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
3,
2,
1,
2,
1
] | 5 | true | Family | 2'-Deoxynucleoside 5'-phosphate N-hydrolase | 2'-Deoxynucleoside 5'-phosphate N-hydrolase | 2'-dNMP_N-hydrolase | 2 |
IPR051240 | 51,240 | Mitochondrial RNA Processing and Respiration | Mito_RNA-Proc/Resp | Family | 8,914 | true | false | The protein family is involved in various mitochondrial functions, including the maintenance of mitochondrial genome expression, RNA processing, and respiration. Members of the family are RNA-binding proteins that participate in the specific removal of group I introns from mitochondrial encoded transcripts, which is cr... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR47933"
] | [
"Mito_RNA-Proc/Resp"
] | [
8914
] | 1 | [] | [] | [] | 0 | [
"6xyw",
"9evs",
"9gyt"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"bioreactor metagenome"
] | [
16,
8897,
1
] | 3 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
63,
1,
30,
52
] | 4 | true | Family | Mitochondrial RNA Processing and Respiration | Mitochondrial RNA Processing and Respiration | Mito_RNA-Proc/Resp | 8 |
IPR051241 | 51,241 | DZIP and RILPL | DZIP_RILPL | Family | 7,137 | true | false | The DZIP/RILPL protein family is involved in the assembly and function of cilia, as well as in cellular transport and cell shape and polarity regulation. Members of the family, such as DZIP1 and DZIP1L, act as molecular adapters recruiting protein complexes to the cilium basal body, facilitating vesicle-mediated transp... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR21502"
] | [
"DZIP_RILPL"
] | [
7137
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DME-5632684",
"R-DRE-5632684",
"R-HSA-2132295",
"R-HSA-5632684",
"R-MMU-2132295",
"R-MMU-5632684"
] | [
"REACTOME:R-DME-5632684",
"REACTOME:R-DRE-5632684",
"REACTOME:R-HSA-2132295",
"REACTOME:R-HSA-5632684",
"REACTOME:R-MMU-2132295",
"REACTOME:R-MMU-5632684"
] | 6 | [
"6rir",
"6sq2",
"7lwb"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Rothia terrae"
] | [
7136,
1
] | 2 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
24,
4,
14,
14,
23
] | 6 | true | Family | DZIP and RILPL | DZIP and RILPL | DZIP_RILPL | 6 |
IPR051243 | 51,243 | Polycomb group WD repeat-containing protein | PcG_WD-repeat | Family | 5,265 | true | false | This family of proteins is involved in epigenetic regulation of gene expression through the modification of histones. Members of this family are part of the Polycomb group (PcG) proteins, which form multiprotein complexes that methylate specific lysine residues on histone H3, leading to transcriptional repression of ta... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR10253"
] | [
"PcG_WD-repeat"
] | [
5265
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-212300",
"R-BTA-2559580",
"R-BTA-3214841",
"R-BTA-8953750",
"R-BTA-9764725",
"R-CEL-2559580",
"R-CEL-8943724",
"R-CEL-9764725",
"R-DRE-212300",
"R-DRE-2559580",
"R-DRE-9764725",
"R-GGA-212300",
"R-GGA-2559580",
"R-GGA-8943724",
"R-GGA-8953750",
"R-GGA-9764725",
"R-HSA-212300",... | [
"REACTOME:R-BTA-212300",
"REACTOME:R-BTA-2559580",
"REACTOME:R-BTA-3214841",
"REACTOME:R-BTA-8953750",
"REACTOME:R-BTA-9764725",
"REACTOME:R-CEL-2559580",
"REACTOME:R-CEL-8943724",
"REACTOME:R-CEL-9764725",
"REACTOME:R-DRE-212300",
"REACTOME:R-DRE-2559580",
"REACTOME:R-DRE-9764725",
"REACTOME:... | 34 | [
"2qxv",
"3iiw",
"3iiy",
"3ij0",
"3ij1",
"3ijc",
"3jpx",
"3jzg",
"3jzh",
"3jzn",
"3k26",
"3k27",
"4w2r",
"4x3e",
"5bjs",
"5gsa",
"5h13",
"5h14",
"5h15",
"5h17",
"5h19",
"5h24",
"5h25",
"5hyn",
"5ij7",
"5ij8",
"5k0m",
"5kjh",
"5kji",
"5kkl",
"5ls6",
"5m5g"... | 89 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
5265
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
3,
1,
2,
7,
8,
4,
1,
2,
3,
14
] | 10 | true | Family | Polycomb group WD repeat-containing protein | Polycomb group WD repeat-containing protein | PcG_WD-repeat | 8 |
IPR051244 | 51,244 | TRPM8 Channel-Associated Factors | TCAF | Family | 4,437 | true | false | The TCAF family is involved in the regulation of the TRPM8 cation channel, with members either positively or negatively affecting the channel's activity. Positive regulators enhance TRPM8 activity, facilitate its recruitment to the cell surface, and inhibit prostate cancer cell migration in a TRPM8-dependent manner. Ne... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR15730"
] | [
"TCAF"
] | [
4437
] | 1 | [] | [] | [] | 0 | [
"4fca",
"5ev7",
"5kd2",
"5kd5",
"5kd8"
] | 5 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriati",
"metagenomes"
] | [
1836,
2580,
7,
14
] | 4 | [
"Danio rerio",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
13,
1,
16,
4,
15
] | 5 | true | Family | TRPM8 Channel-Associated Factors | TRPM8 Channel-Associated Factors | TCAF | 8 |
IPR051245 | 51,245 | eIF5-mimic translation initiation regulator | eIF5-mimic_regulator | Family | 5,381 | true | true | The elf5-mimic protein family functions as translation initiation regulators. They are known to repress non-AUG-initiated translation and repeat-associated non-AUG (RAN)-initiated translation, acting as competitive inhibitors of eukaryotic translation initiation factor 5 (EIF5). These proteins increase the accuracy of ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR14208"
] | [
"eIF5-mimic_regulator"
] | [
5381
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00095038",
"PUB00160431",
"PUB00160432"
] | [
"10075937",
"11524015",
"28981728"
] | [
"Conserved bipartite motifs in yeast eIF5 and eIF2Bepsilon, GTPase-activating and GDP-GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2.",
"Purification and functional analysis of a novel leucine-zipper/nucleotide-fold protein, BZAP45, stimulating cell cycle regulated ... | [
1999,
2001,
2017
] | 3 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
5381
] | 1 | [
"Arabidopsis thaliana",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
13,
10,
1,
23,
14,
7,
7,
14
] | 8 | true | Family | eIF5-mimic translation initiation regulator | eIF5-mimic translation initiation regulator | eIF5-mimic_regulator | 7 |
IPR051247 | 51,247 | RISC Loading Complex Component | RLC_Component | Family | 4,374 | true | false | This family of proteins is involved in the RNA interference (RNAi) pathway and plays a critical role in the formation of the RNA-induced silencing complex (RISC). Members of this family are part of the RISC loading complex (RLC), which processes precursor microRNAs (pre-miRNAs) into mature miRNAs and loads them onto Ar... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR46205"
] | [
"RLC_Component"
] | [
4374
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-203927",
"R-BTA-426486",
"R-BTA-9833482",
"R-DME-203927",
"R-DME-426486",
"R-DME-9833482",
"R-DRE-9833482",
"R-HSA-203927",
"R-HSA-426486",
"R-HSA-9833482",
"R-MMU-203927",
"R-MMU-426486",
"R-MMU-9833482",
"R-RNO-203927",
"R-RNO-426486",
"R-RNO-9833482",
"R-XTR-203927",
"R-X... | [
"REACTOME:R-BTA-203927",
"REACTOME:R-BTA-426486",
"REACTOME:R-BTA-9833482",
"REACTOME:R-DME-203927",
"REACTOME:R-DME-426486",
"REACTOME:R-DME-9833482",
"REACTOME:R-DRE-9833482",
"REACTOME:R-HSA-203927",
"REACTOME:R-HSA-426486",
"REACTOME:R-HSA-9833482",
"REACTOME:R-MMU-203927",
"REACTOME:R-MMU... | 19 | [
"1di2",
"1qu6",
"2cpn",
"2dix",
"2ltr",
"2lts",
"3adl",
"3llh",
"4wyq",
"4x8w",
"5n8l",
"5n8m",
"5npa",
"5npg",
"5zak",
"5zal",
"5zam",
"6zbk",
"7v6b",
"7v6c",
"7w0a",
"7w0b",
"7w0c",
"7w0d",
"7w0e",
"7w0f",
"7zpj",
"7zpk",
"8dfv",
"8dg5",
"8dg7",
"8dga"... | 42 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
38,
4240,
89,
7
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
3,
1,
3,
31,
27,
11,
1,
8,
5
] | 9 | true | Family | RISC Loading Complex Component | RISC Loading Complex Component | RLC_Component | 3 |
IPR051248 | 51,248 | UPF0507/Ankyrin repeat domain-containing protein 27 | UPF0507/Ank_repeat_27 | Family | 3,860 | true | false | The UPF0507/Ankyrin repeat domain-containing protein 27 family is involved in various cellular processes including endosome dynamics, vesicle trafficking, and membrane fusion events. Members of the family may act as guanine exchange factors (GEFs) for Rab GTPases such as Rab21, Rab32, and Rab38, regulating their activi... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR24170"
] | [
"UPF0507/Ank_repeat_27"
] | [
3860
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DDI-8876198",
"R-HSA-8876198",
"R-MMU-8876198"
] | [
"REACTOME:R-DDI-8876198",
"REACTOME:R-HSA-8876198",
"REACTOME:R-MMU-8876198"
] | 3 | [
"4b93",
"4cym",
"4cz2",
"6tl0"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3860
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
7,
6,
7,
1,
5,
2
] | 6 | true | Family | UPF0507/Ankyrin repeat domain-containing protein 27 | UPF0507/Ankyrin repeat domain-containing protein 27 | UPF0507/Ank_repeat_27 | 6 |
IPR051249 | 51,249 | NLRP Inflammasome | NLRP_Inflammasome | Family | 3,792 | true | false | The NLRP inflammasome family plays a crucial role in innate immunity and inflammation. Members of this family act as cytosolic pattern recognition receptors (PRRs) that detect pathogen-associated signals, leading to the assembly of inflammasome complexes. These complexes recruit and activate caspase-1, which processes ... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR46985"
] | [
"NLRP_Inflammasome"
] | [
3792
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-DRE-111458",
"R-DRE-6798695",
"R-DRE-844455",
"R-DRE-844456",
"R-DRE-9627069",
"R-HSA-111458",
"R-HSA-5660668",
"R-HSA-6798695",
"R-HSA-844455",
"R-HSA-844456",
"R-HSA-844615",
"R-HSA-9627069",
"R-HSA-9660826",
"R-HSA-9692916",
"R-MMU-5660668",
"R-MMU-6798695",
"R-MMU-844455",
"... | [
"REACTOME:R-DRE-111458",
"REACTOME:R-DRE-6798695",
"REACTOME:R-DRE-844455",
"REACTOME:R-DRE-844456",
"REACTOME:R-DRE-9627069",
"REACTOME:R-HSA-111458",
"REACTOME:R-HSA-5660668",
"REACTOME:R-HSA-6798695",
"REACTOME:R-HSA-844455",
"REACTOME:R-HSA-844456",
"REACTOME:R-HSA-844615",
"REACTOME:R-HSA... | 19 | [
"2kn6",
"3kat",
"5h8o",
"6k7v",
"6k99",
"6k9f",
"6n1h",
"6x6a",
"6x6c",
"6xkj",
"6xkk",
"7crv",
"7crw",
"7jkq",
"7jn7",
"7keu"
] | 16 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Gnathostomata"
] | [
3792
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
14,
22,
14,
18
] | 4 | true | Family | NLRP Inflammasome | NLRP Inflammasome | NLRP_Inflammasome | 7 |
IPR051251 | 51,251 | Ser/Thr-Protein Kinase & FNIP Repeat-Containing Protein | STK_FNIP-Repeat | Family | 3,367 | true | false | This family of proteins includes serine/threonine-protein kinases and proteins containing FNIP repeats. The kinases are part of the protein kinase superfamily and the STE Ser/Thr protein kinase family, suggesting a role in phosphorylation of serine and threonine residues in substrate proteins, which is a common mechani... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR32134"
] | [
"STK_FNIP-Repeat"
] | [
3367
] | 1 | [] | [] | [] | 0 | [
"6nyr",
"6nys",
"7zal"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
155,
2189,
862,
161
] | 4 | [] | [] | 0 | true | Family | Ser/Thr-Protein Kinase & FNIP Repeat-Containing Protein | Ser/Thr-Protein Kinase & FNIP Repeat-Containing Protein | STK_FNIP-Repeat | 6 |
IPR051252 | 51,252 | IS1 element transposase InsA | IS1_transposase_InsA | Family | 2,239 | true | false | This family of proteins is essential for the transposition of IS1 elements. Members of this family are involved in the mobility of these small genetic elements, which can move within a genome. Transposition is a key process by which these elements can cause mutations, rearrangements, or gene disruptions, contributing t... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR47923"
] | [
"IS1_transposase_InsA"
] | [
2239
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Escherichia phage P1",
"metagenomes"
] | [
2214,
2,
23
] | 3 | [
"Escherichia coli (strain K12)"
] | [
9
] | 1 | true | Family | IS1 element transposase InsA | IS1 element transposase InsA | IS1_transposase_InsA | 3 |
IPR051253 | 51,253 | 11-beta-hydroxysteroid dehydrogenase | 11-beta-HSD | Family | 2,523 | true | false | This family of proteins is involved in the regulation of glucocorticoid and mineralocorticoid levels by catalyzing the reversible conversion of inactive glucocorticoids to their active forms. They function predominantly as reductases in vivo, increasing the concentration of active glucocorticoids. These proteins play a... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR44279"
] | [
"11-beta-HSD"
] | [
2523
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"1.1.1",
"R-DRE-194002",
"R-DRE-9757110",
"R-HSA-194002",
"R-HSA-9757110",
"R-MMU-194002",
"R-MMU-9757110",
"R-RNO-194002",
"R-RNO-9757110"
] | [
"EC:1.1.1",
"REACTOME:R-DRE-194002",
"REACTOME:R-DRE-9757110",
"REACTOME:R-HSA-194002",
"REACTOME:R-HSA-9757110",
"REACTOME:R-MMU-194002",
"REACTOME:R-MMU-9757110",
"REACTOME:R-RNO-194002",
"REACTOME:R-RNO-9757110"
] | 9 | [
"1xse",
"1xu7",
"1xu9",
"1y5m",
"1y5r",
"2bel",
"2ilt",
"2irw",
"2rbe",
"3byz",
"3bzu",
"3ch6",
"3czr",
"3d3e",
"3d4n",
"3d5q",
"3dwf",
"3ey4",
"3fco",
"3frj",
"3g49",
"3gmd",
"3h6k",
"3hfg",
"3lz6",
"3oq1",
"3pdj",
"3qqp",
"3tfq",
"4bb5",
"4bb6",
"4c7j"... | 53 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Candidatus Thermofonsia Clade 1 bacterium",
"Eukaryota"
] | [
1,
2522
] | 2 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
9,
5,
5
] | 4 | true | Family | 11-beta-hydroxysteroid dehydrogenase | 11-beta-hydroxysteroid dehydrogenase | 11-beta-HSD | 6 |
IPR051254 | 51,254 | Protein Phosphatase 1 Regulatory Subunit 15 | PPP1R15 | Family | 2,098 | true | false | The PPP1R15 family proteins are involved in the regulation of protein synthesis and stress responses in cells. They recruit the serine/threonine-protein phosphatase PPP1CA to dephosphorylate EIF2S1/eIF-2A, reversing protein synthesis shutdown by stress kinases and aiding cell recovery from stress. They modulate the TGF... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR16489"
] | [
"PPP1R15"
] | [
2098
] | 1 | [
"REACTOME",
"REACTOME"
] | [
"R-HSA-2173788",
"R-HSA-9648895"
] | [
"REACTOME:R-HSA-2173788",
"REACTOME:R-HSA-9648895"
] | 2 | [
"4v0u",
"4v0w",
"4v0x",
"4xpn",
"7nxv",
"9nb9"
] | 6 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Metazoa",
"Viruses"
] | [
1829,
269
] | 2 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
1,
12,
4,
8
] | 5 | true | Family | Protein Phosphatase 1 Regulatory Subunit 15 | Protein Phosphatase 1 Regulatory Subunit 15 | PPP1R15 | 6 |
IPR051255 | 51,255 | Retroviral envelope glycoprotein | Retroviral_env_glycoprotein | Family | 967 | true | false | This family of proteins includes envelope glycoproteins from various retroviruses, including endogenous retroviruses (ERVs) and exogenous viruses like mouse mammary tumor virus (MMTV) and Jaagsiekte sheep retrovirus (JSRV). The primary functions involve receptor recognition and membrane fusion during viral entry into h... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR34313"
] | [
"Retroviral_env_glycoprotein"
] | [
967
] | 1 | [] | [] | [] | 0 | [
"9mla",
"9mlk",
"9nnd",
"9o4f"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bilateria",
"Ortervirales"
] | [
578,
389
] | 2 | [
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
61,
3,
1
] | 3 | true | Family | Retroviral envelope glycoprotein | Retroviral envelope glycoprotein | Retroviral_env_glycoprotein | 6 |
IPR051256 | 51,256 | Dictomallein | Dictomallein | Family | 637 | true | false | The Dictomallein family comprises proteins with a shared similarity, indicating a potential common functional or structural characteristic. However, the specific function of the Dictomallein family members, aside from the Metalloprotease StcE, is not detailed in the provided information. The Metalloprotease StcE is a v... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR39540"
] | [
"Dictomallein"
] | [
637
] | 1 | [
"EC",
"METACYC"
] | [
"3.4.24.-",
"PWY-8119"
] | [
"EC:3.4.24.-",
"METACYC:PWY-8119"
] | 2 | [
"3ujz"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"marine metagenome"
] | [
590,
46,
1
] | 3 | [] | [] | 0 | true | Family | Dictomallein | Dictomallein | Dictomallein | 3 |
IPR051257 | 51,257 | Diverse Function CBS-Domain-Containing Protein | Diverse_CBS-Domain | Family | 61,934 | true | false | This family of proteins includes members with diverse functions, some of which are uncharacterized. A subset of proteins within this family are involved in the cellular response to hypoxia, but do not bind AMP, which is a common function of other CBS-domain containing proteins. Another subset is implicated in the metab... | [] | [] | [] | 0 | [
"PANTHER"
] | [
"PTHR43080"
] | [
"Diverse_CBS-Domain"
] | [
61934
] | 1 | [] | [] | [] | 0 | [
"1o50",
"1pbj",
"1pvm",
"1xkf",
"1y5h",
"1yav",
"2ef7",
"2emq",
"2o16",
"2qh1",
"2rc3",
"2rif",
"2rih",
"2yzi",
"3ddj",
"3fhm",
"3ghd",
"3kh5",
"3kpb",
"3kpc",
"3kpd",
"3l2b",
"3l31",
"3lfz",
"3lqn",
"4esy",
"4fry",
"4noc",
"5g5r",
"5g5x",
"5nmu",
"5npl"... | 45 | [
"PUB00161770"
] | [
"40676158"
] | [
"Structure of an archaeal ribosome reveals a divergent active site and hibernation factor."
] | [
2025
] | 1 | [] | [
"IPR017158"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"Siphoviridae sp. ctYaH2",
"unclassified sequences"
] | [
7210,
51682,
2275,
1,
766
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
6,
1,
12,
21
] | 4 | true | Family | Diverse Function CBS-Domain-Containing Protein | Diverse Function CBS-Domain-Containing Protein | Diverse_CBS-Domain | 5 |
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