LiteFold/InterPro · Datasets at Hugging Face

IPR053222

53,222

Zygotic Embryogenesis-Associated Protein

Zygotic_Embryogenesis-Asso

Family

1,645

true

false

This family of proteins may be involved in the developmental processes that occur during embryogenesis. The exact role in embryonic development is not clearly defined, but members of this family are thought to contribute to the proper progression of embryonic stages.

[]

0

[ "PANTHER" ]

[ "PTHR22899" ]

[ "Zygotic_Embryogenesis-Asso" ]

[ 1645 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Caenorhabditis" ]

[ 1645 ]

1

[ "Caenorhabditis elegans" ]

[ 153 ]

1

true

Family

Zygotic Embryogenesis-Associated Protein

Zygotic_Embryogenesis-Asso

6

IPR053223

53,223

Probable Methyltransferase

Prob_Methyltransferase

Family

3,306

true

false

This family of proteins includes enzymes that are characterized by their ability to transfer methyl groups to various substrates. Methyltransferases are involved in a wide range of biological processes, including the modification of DNA, RNA, proteins, and small molecules, which can affect gene expression, protein func...

[]

0

[ "PANTHER" ]

[ "PTHR44067" ]

[ "Prob_Methyltransferase" ]

[ 3306 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 3306 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 25, 17, 40 ]

3

true

Family

Probable Methyltransferase

Prob_Methyltransferase

3

IPR053224

53,224

Sensory map formation adhesion molecule

Sensory_adhesion_molecule

Family

2,617

true

false

This family of proteins includes adhesion molecules that play a crucial role in the development of sensory processes within the nervous system. They are specifically involved in the formation of sensory maps, which are essential for processing sensory information and establishing the necessary neural connections.

[]

0

[ "PANTHER" ]

[ "PTHR31460" ]

[ "Sensory_adhesion_molecule" ]

[ 2617 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Haloferacaceae", "ecological metagenomes" ]

[ 880, 1732, 2, 3 ]

4

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 21, 2, 14, 14 ]

4

true

Family

Sensory map formation adhesion molecule

Sensory_adhesion_molecule

6

IPR053225

53,225

Acyl-CoA N-acyltransferase VerG-like

Acyl-CoA_N-acyltransferase

Family

2,428

true

false

This family of proteins includes acyl-CoA N-acyltransferases involved in the biosynthesis of specific neurotoxins, such as verrucosidin, which is a methylated alpha-pyrone polyketide. These enzymes are responsible for the modification of the carbon backbone produced by polyketide synthases, contributing to the producti...

[]

0

[ "PANTHER" ]

[ "PTHR20958" ]

[ "Acyl-CoA_N-acyltransferase" ]

[ 2428 ]

1

[]

0

[ "1sqh" ]

1

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "bioreactor metagenome" ]

[ 143, 2280, 5 ]

3

[ "Caenorhabditis elegans", "Drosophila melanogaster", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1, 14, 1 ]

3

true

Family

Acyl-CoA N-acyltransferase VerG-like

Acyl-CoA_N-acyltransferase

3

IPR053226

53,226

Pyrrolopyrazine biosynthesis cluster protein F

Pyrrolopyrazine_biosynth_F

Family

2,169

true

Pyrrolopyrazine biosynthesis cluster protein F, also known as Sulfotransferase ppzF, is involved in the biosynthesis of pyrrolopyrazines, which are secondary metabolites with insecticidal properties [ ]. The protein includes a multifunctional non-ribosomal peptide synthetase (NRPS) that synthesises peramine, a simple p...

[]

0

[ "PANTHER" ]

[ "PTHR48419" ]

[ "" ]

[ 2169 ]

1

[]

0

[]

0

[ "PUB00155230" ]

[ "30452111" ]

[ "Orthologous peramine and pyrrolopyrazine-producing biosynthetic gene clusters in Metarhizium rileyi, Metarhizium majus and Cladonia grayi." ]

[ 2019 ]

1

[]

0

null

[ "Bacteria", "Eukaryota", "marine metagenome" ]

[ 274, 1894, 1 ]

3

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Family

Pyrrolopyrazine biosynthesis cluster protein F

Pyrrolopyrazine_biosynth_F

8

IPR053227

53,227

TRPL channel trafficking regulator

TRPL-trafficking_regulator

Family

1,820

true

false

This family of proteins includes GTP-binding proteins involved in the trafficking of ion channels in photoreceptor cells. They play a crucial role in the light-dependent internalization and recycling of specific ion channels, such as the TRPL channel, between the rhabdomere and the cell body. Members of this family are...

[]

0

[ "PANTHER" ]

[ "PTHR34932" ]

[ "TRPL-trafficking_regulator" ]

[ 1820 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes", "uncultured Caudovirales phage" ]

[ 341, 1475, 3, 1 ]

4

[ "Caenorhabditis elegans", "Drosophila melanogaster" ]

[ 5, 2 ]

2

true

Family

TRPL channel trafficking regulator

TRPL-trafficking_regulator

4

IPR053228

53,228

Stereospecific Lipase

Stereospecific_Lipase

Family

2,037

true

false

This family of proteins is involved in the enzymatic breakdown of triglycerides into their component fatty acids and glycerol, a process known as hydrolysis. Members of this family exhibit a high degree of stereospecificity, meaning they can distinguish between molecularly similar compounds based on their three-dimensi...

[]

0

[ "PANTHER" ]

[ "PTHR37574" ]

[ "Stereospecific_Lipase" ]

[ 2037 ]

1

[]

0

[ "1lbs", "1lbt", "1tca", "1tcb", "1tcc", "3icv", "3icw", "3w9b", "4k5q", "4k6g", "4k6h", "4k6k", "4zv7", "5a6v", "5a71", "5gv5", "6idy", "6isp", "6isq", "6isr", "6j1p", "6j1q", "6j1r", "6j1s", "6j1t", "6tp8", "7v6d", "9evi", "9fde" ]

29

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "freshwater metagenome" ]

[ 858, 1172, 7 ]

3

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Family

Stereospecific Lipase

Stereospecific_Lipase

4

IPR053229

53,229

NADH-ubiquinone oxidoreductase subunit

NADH-Q_oxidrdct_subunit

Family

2,357

true

false

This family of proteins is involved in the mitochondrial electron transport chain, specifically in the initial stage of transferring electrons from NADH to ubiquinone. Members of this family serve as subunits in the NADH-ubiquinone oxidoreductase complex, also known as Complex I, which is the first enzyme in the respir...

[]

0

[ "PANTHER" ]

[ "PTHR34062" ]

[ "NADH-Q_oxidrdct_subunit" ]

[ 2357 ]

1

[]

0

[ "6gcs", "6rfq", "6rfr", "6rfs", "6x89", "6y79", "6yj4", "7a23", "7a24", "7aqq", "7ar7", "7ar8", "7ar9", "7arb", "7ard", "7b0n", "7o6y", "7o71", "7zkp", "7zm7", "7zm8", "7zmb", "7zme", "7zmg", "7zmh", "8bef", "8bpx", "8bq5", "8bq6", "8e73", "9f5x", "9f5y"...

37

[]

0

[]

0

null

[ "Eukaryota" ]

[ 2357 ]

1

[ "Arabidopsis thaliana", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 6, 1, 6, 4 ]

4

true

Family

NADH-ubiquinone oxidoreductase subunit

NADH-Q_oxidrdct_subunit

3

IPR053230

53,230

Transcription regulator galc

Trans_reg_galc

Family

2,027

true

false

The Transcription regulator galc family includes transcription factors that play a crucial role in the negative regulation of ochratoxin A biosynthesis, a harmful mycotoxin with various toxic properties. Members of this family are also involved in maintaining cellular redox balance and modulating the cell's response to...

[]

0

[ "PANTHER" ]

[ "PTHR47654" ]

[ "Trans_reg_galc" ]

[ 2027 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 2027 ]

1

[]

0

true

Family

Transcription regulator galc

Trans_reg_galc

5

IPR053231

53,231

G-protein coupled receptor LN-TM7

GPCR_LN-TM7

Family

3,167

true

false

This family of proteins includes G-protein coupled receptors (GPCRs) that are part of the LN-TM7 subfamily. GPCRs are a large family of cell surface receptors that respond to a variety of external signals and activate intracellular signal transduction pathways and cellular responses. Being part of the LN-TM7 subfamily,...

[]

0

[ "PANTHER" ]

[ "PTHR45902" ]

[ "GPCR_LN-TM7" ]

[ 3167 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 3167 ]

1

[]

0

true

Family

G-protein coupled receptor LN-TM7

GPCR_LN-TM7

8

IPR053232

53,232

Chloroplastic DnaJ C/III subfamily chaperone

DnaJ_C/III_chloroplastic

Family

2,074

true

false

This family of proteins is involved in plant development and is likely important for the structural organization of cellular compartments. Members of this family are characterized by their role as chaperones, which suggests they may assist in protein folding, assembly, translocation, or degradation. As part of the DnaJ...

[]

0

[ "PANTHER" ]

[ "PTHR45090" ]

[ "DnaJ_C/III_chloroplastic" ]

[ 2074 ]

1

[]

0

[ "7am2" ]

1

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Podoviridae sp. ctIi96", "ecological metagenomes" ]

[ 5, 94, 1972, 1, 2 ]

5

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 7, 8, 12 ]

3

true

Family

Chloroplastic DnaJ C/III subfamily chaperone

DnaJ_C/III_chloroplastic

5

IPR053233

53,233

Plasmodium ABRA-related

ABRA-related

Family

1,928

true

false

This family of proteins is implicated in the asexual blood stage of a parasitic lifecycle, where they play a role in the invasion of host erythrocytes. They achieve this by interacting with a specific host cell surface protein, which facilitates the entry of the parasite into the red blood cells without the need for si...

[]

0

[ "PANTHER" ]

[ "PTHR21715" ]

[ "ABRA-related" ]

[ 1928 ]

1

[]

0

[ "7nwj", "7o06", "7o0s", "7o3b" ]

4

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1928 ]

1

[ "Danio rerio", "Drosophila melanogaster", "Homo sapiens" ]

[ 1, 1, 4 ]

3

true

Family

Plasmodium ABRA-related

ABRA-related

1

IPR053234

53,234

RPM1 Interacting Protein

RPM1_Interactor

Family

2,306

true

false

This family of proteins interacts with resistance proteins to enhance plant defense mechanisms against certain bacterial pathogens. Members of this family are involved in promoting resistance to necrotrophic bacteria by positively regulating specific resistance proteins. They play a role in preventing the hypersensitiv...

[]

0

[ "PANTHER" ]

[ "PTHR33443" ]

[ "RPM1_Interactor" ]

[ 2306 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 2306 ]

1

[ "Arabidopsis thaliana", "Danio rerio", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 23, 1, 11, 19 ]

4

true

Family

RPM1 Interacting Protein

RPM1_Interactor

1

IPR053235

53,235

Ser/Thr Protein Kinase

Ser_Thr_kinase

Family

8,896

true

false

This family of proteins includes serine/threonine kinases, which are a type of enzyme that modifies other proteins by chemically adding phosphate groups to them. Members of this family are involved in a wide range of cellular processes, including the regulation of cell division, signal transduction pathways, and the re...

[]

0

[ "PANTHER" ]

[ "PTHR24361" ]

[ "Ser_Thr_kinase" ]

[ 8896 ]

1

[ "EC", "REACTOME" ]

[ "2.7.11.1", "R-DDI-383280" ]

[ "EC:2.7.11.1", "REACTOME:R-DDI-383280" ]

2

[ "7xbr" ]

1

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "Viruses", "unclassified sequences" ]

[ 16, 2204, 6591, 38, 47 ]

5

[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Zea mays" ]

[ 11, 3, 1, 1, 24, 1, 56 ]

7

true

Family

Ser/Thr Protein Kinase

Ser_Thr_kinase

9

IPR053237

53,237

Natterin, C-terminal

Natterin_C

Domain

2,357

false

This entry represents a domain found in Natterin-1 from Thalassophryne nattereri and similar sequences. This protein shows nociceptive, edema-inducing and kininogenase activity with release of kallidin from low molecular weight kininogen. Its proteolytic activity of these proteins specifically targets Met-Lys bonds [ ]...

[]

0

[ "PANTHER" ]

[ "PTHR39244" ]

[ "" ]

[ 2357 ]

1

[]

0

[ "1jlx", "1jly", "1w3a", "1w3f", "1w3g" ]

5

[ "PUB00056184" ]

[ "16054523" ]

[ "Natterins, a new class of proteins with kininogenase activity characterized from Thalassophryne nattereri fish venom." ]

[ 2005 ]

1

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 115, 2242 ]

2

[ "Zea mays" ]

[ 12 ]

1

true

Domain

Natterin, C-terminal

Natterin_C

6

IPR053238

53,238

RING-H2 finger domain-containing protein

RING-H2_zinc_finger

Family

8,551

true

false

This family of proteins includes members that contain a RING-type zinc finger domain, which is characteristic of a group of E3 ubiquitin ligases. These proteins are involved in the ubiquitination pathway, where they play a role in the transfer of ubiquitin from an E2 ubiquitin-conjugating enzyme to specific substrate p...

[]

0

[ "PANTHER" ]

[ "PTHR14155" ]

[ "RING-H2_zinc_finger" ]

[ 8551 ]

1

[ "EC", "METACYC" ]

[ "2.3.2.27", "PWY-7511" ]

[ "EC:2.3.2.27", "METACYC:PWY-7511" ]

2

[]

0

[]

0

[]

0

null

[ "Eukaryota", "Viruses", "metagenomes" ]

[ 8499, 7, 45 ]

3

[ "Arabidopsis thaliana", "Danio rerio", "Oryza sativa subsp. japonica", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Zea mays" ]

[ 81, 2, 121, 1, 130 ]

5

true

Family

RING-H2 finger domain-containing protein

RING-H2_zinc_finger

5

IPR053239

53,239

Dual specificity protein-tyrosine phosphatase

Dual_spec_PTase

Family

1,738

true

false

This family of proteins includes dual specificity phosphatases that are involved in the regulation of the cell cycle, particularly during the DNA synthesis phase. Members of this family are characterized by their ability to dephosphorylate serine, threonine, and tyrosine residues, which is a key process in cell signali...

[]

0

[ "PANTHER" ]

[ "PTHR47550" ]

[ "Dual_spec_PTase" ]

[ 1738 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1738 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1, 1 ]

2

true

Family

Dual specificity protein-tyrosine phosphatase

Dual_spec_PTase

8

IPR053240

53,240

VTT domain-containing protein

VTT_domain

Family

1,579

true

false

This family of proteins includes members that are integral to cellular membranes and are thought to be involved in various cellular processes. The characteristic feature of this family is the presence of the VTT domain, which was initially thought to be associated with SNARE proteins but was later redefined due to lack...

[]

0

[ "PANTHER" ]

[ "PTHR46826" ]

[ "VTT_domain" ]

[ 1579 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 522, 1050, 7 ]

3

[ "Arabidopsis thaliana", "Escherichia coli (strain K12)", "Homo sapiens", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 6, 1, 1, 6, 10 ]

5

true

Family

VTT domain-containing protein

VTT_domain

2

IPR053241

53,241

NADPH-dependent pterin aldehyde reductase

NADPH_pterin_aldehyde_rdct

Family

1,121

true

false

The NADPH-dependent pterin aldehyde reductase family is involved in the salvage of pterin aldehydes during folate turnover. Members of this family are capable of reducing a variety of aromatic and aliphatic aldehydes, including acetaldehyde and benzaldehyde, among others. The family is characterized by its ability to c...

[]

0

[ "PANTHER" ]

[ "PTHR45267" ]

[ "NADPH_pterin_aldehyde_rdct" ]

[ 1121 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 389, 725, 7 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 4, 3, 11 ]

3

true

Family

NADPH-dependent pterin aldehyde reductase

NADPH_pterin_aldehyde_rdct

2

IPR053242

53,242

PAM2-like motif domain-containing protein

PAM2-like_domain

Family

1,966

true

false

This family of proteins includes members that are known to interact with polyadenylate-binding proteins (PABPs) through a specific motif resembling the PAM2 motif. This motif is typically involved in recognizing and binding to the PABC/CTC domain of PABPs, suggesting a role in mRNA metabolism. PABPs are key regulators ...

[]

0

[ "PANTHER" ]

[ "PTHR46651" ]

[ "PAM2-like_domain" ]

[ 1966 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1966 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 8, 13, 46 ]

3

true

Family

PAM2-like motif domain-containing protein

PAM2-like_domain

2

IPR053243

53,243

Septate junction maturation regulator

SJ_maturation_regulator

Family

2,208

true

false

This family of proteins is essential for the development and maturation of septate junctions, which are key structures in the epithelial tissue that contribute to cell adhesion and barrier formation. Members of this family are involved in the localization of core components of septate junctions during late embryogenesi...

[]

0

[ "PANTHER" ]

[ "PTHR47653" ]

[ "SJ_maturation_regulator" ]

[ 2208 ]

1

[ "REACTOME" ]

[ "R-MMU-5683826" ]

[ "REACTOME:R-MMU-5683826" ]

1

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Stenosarchaea group", "ecological metagenomes" ]

[ 23, 2176, 7, 2 ]

4

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 1, 2, 1, 1, 5, 13 ]

6

true

Family

Septate junction maturation regulator

SJ_maturation_regulator

5

IPR053244

53,244

Histone deacetylase HD type 1

HDAC_HD_type_1

Family

1,575

true

false

This family of proteins is involved in the removal of acetyl groups from lysine residues at the N-terminal part of core histones, including H2A, H2B, H3, and H4. This action is crucial for epigenetic repression, as it marks the histones for a state that is generally associated with condensed, transcriptionally inactive...

[]

0

[ "PANTHER" ]

[ "PTHR47558" ]

[ "HDAC_HD_type_1" ]

[ 1575 ]

1

[]

0

[ "7wjl" ]

1

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1575 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1, 1 ]

2

true

Family

Histone deacetylase HD type 1

HDAC_HD_type_1

4

IPR053245

53,245

Mitochondrial Process-Associated

MitoProcess-Associated

Family

1,575

true

false

This family of proteins is involved in various cellular processes within the mitochondria. The specific functions of these proteins may include roles in mitochondrial maintenance, energy metabolism, and the regulation of mitochondrial gene expression. They may also participate in the assembly of mitochondrial complexes...

[]

0

[ "PANTHER" ]

[ "PTHR47563" ]

[ "MitoProcess-Associated" ]

[ 1575 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1575 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1, 1 ]

2

true

Family

Mitochondrial Process-Associated

MitoProcess-Associated

7

IPR053246

53,246

Nuclear speckle splicing regulatory protein

NS_splicing_regulatory_protein

Family

1,583

true

false

This family of proteins is involved in the regulation of pre-mRNA splicing within the cell nucleus. Members of this family are typically localized to nuclear speckles, which are dynamic structures implicated in the storage and modification of splicing factors. Proteins in this family may play a role in the assembly and...

[]

0

[ "PANTHER" ]

[ "PTHR47845" ]

[ "NS_splicing_regulatory_protein" ]

[ 1583 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1583 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)" ]

[ 1, 1 ]

2

true

Family

Nuclear speckle splicing regulatory protein

NS_splicing_regulatory_protein

7

IPR053247

53,247

G protein-coupled receptor GPR1/git3-like

GPCR_GPR1/git3-like

Family

1,526

true

false

This family of proteins includes G protein-coupled receptors that are involved in the process of conidiation and the regulation of secondary metabolite biosynthesis, such as dihydroxynaphthalene (DHN)-melanin. These receptors function through interactions with G-protein complexes, particularly the alpha subunit, to exe...

[]

0

[ "PANTHER" ]

[ "PTHR42058" ]

[ "GPCR_GPR1/git3-like" ]

[ 1526 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1526 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Family

G protein-coupled receptor GPR1/git3-like

GPCR_GPR1/git3-like

5

IPR053248

53,248

Zinc finger MYND domain-containing protein

Zinc_finger_MYND_domain

Family

1,505

true

false

This family of proteins includes members that contain a zinc finger MYND-type domain, which is known to mediate protein-protein interactions. These interactions often involve chromatin remodeling complexes, suggesting a role in transcriptional regulation. The MYND domain typically recognizes specific peptide sequences ...

[]

0

[ "PANTHER" ]

[ "PTHR46533" ]

[ "Zinc_finger_MYND_domain" ]

[ 1505 ]

1

[]

0

[ "8glv", "8j07", "9d2f", "9e5c", "9fqr" ]

5

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1505 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 3, 3, 2, 5 ]

4

true

Family

Zinc finger MYND domain-containing protein

Zinc_finger_MYND_domain

4

IPR053249

53,249

Lachrymatory-factor Synthase

LFS

Family

2,000

true

false

This family of proteins is involved in the production of a compound known as the lacrymatory factor, which is responsible for causing tears. The enzyme catalyzes the transformation of 1-propenylsulphenic acid into the lacrymatory factor. The 1-propenylsulphenic acid is an unstable intermediate that is generated from th...

[]

0

[ "PANTHER" ]

[ "PTHR33789" ]

[ "LFS" ]

[ 2000 ]

1

[]

0

[ "5e46", "5e4b", "5e4d", "5e4m", "5gte", "5gtf", "5gtg", "5vgl", "5vgs", "6ies" ]

10

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "freshwater metagenome" ]

[ 40, 1959, 1 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 6, 15, 13 ]

3

true

Family

Lachrymatory-factor Synthase

LFS

9

IPR053250

53,250

Glycosyltransferase 77 domain-containing protein

Glycosyltransferase_77

Family

1,708

true

false

This family of proteins includes enzymes that are involved in the modification of cell wall components through the process of arabinosylation. Members of this family are responsible for adding arabinose, a sugar molecule, to extensin proteins, which are structural glycoproteins present in plant cell walls. The arabinos...

[]

0

[ "PANTHER" ]

[ "PTHR46936" ]

[ "Glycosyltransferase_77" ]

[ 1708 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 2, 1706 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 5, 4, 5 ]

3

true

Family

Glycosyltransferase 77 domain-containing protein

Glycosyltransferase_77

6

IPR053251

53,251

Peptide-N(4)-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F

PNGF

Family

671

true

This family of proteins inckudes Peptide-N(4)-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F (PNGF), which is involved in the enzymatic process of detaching glycans from glycoproteins. The enzymatic activity is specific to glycosylated asparagine residues that are flanked by polypeptide chains. The cleavage mechani...

[]

0

[ "PANTHER" ]

[ "PTHR39319" ]

[ "N-glycanase" ]

[ 671 ]

1

[]

0

[ "1pgs", "1pnf", "1png", "3pms" ]

4

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Methanobacteriati", "ecological metagenomes" ]

[ 200, 440, 6, 25 ]

4

[ "Danio rerio" ]

[ 1 ]

1

true

Family

Peptide-N(4)-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F

PNGF

2

IPR053252

53,252

Epithelial-mesenchymal transition regulator

EMT_regulator

Family

1,379

true

false

This family of proteins is involved in the regulation of cellular processes that prevent epithelial cells from undergoing a transformation into a mesenchymal cell state. They play a role in maintaining cell polarity and adhesion, thereby inhibiting the increased migratory and invasive capabilities that characterize the...

[]

0

[ "PANTHER" ]

[ "PTHR46970" ]

[ "EMT_regulator" ]

[ 1379 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eumetazoa" ]

[ 1379 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 1, 2, 3, 3 ]

4

true

Family

Epithelial-mesenchymal transition regulator

EMT_regulator

3

IPR053253

53,253

Sexual differentiation modulator

Sex_diff_modulator

Family

1,425

true

false

This family of proteins is implicated in the modulation of reproductive processes, specifically in the transition from asexual to sexual reproductive modes. Members of this family may play a role in determining the reproductive pathway in their respective organisms.

[]

0

[ "PANTHER" ]

[ "PTHR33087" ]

[ "Sex_diff_modulator" ]

[ 1425 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "commelinids" ]

[ 1425 ]

1

[ "Oryza sativa subsp. japonica", "Zea mays" ]

[ 109, 17 ]

2

true

Family

Sexual differentiation modulator

Sex_diff_modulator

2

IPR053254

53,254

Small GTPase Arf-like protein

Arf-like_GTPase

Family

1,396

true

false

This family of proteins includes members that are part of the small GTPase superfamily, specifically the Arf subfamily. These proteins are involved in various cellular processes including the regulation of vesicular trafficking, actin cytoskeleton organization, and lipid metabolism. They function as molecular switches ...

[]

0

[ "PANTHER" ]

[ "PTHR46724" ]

[ "Arf-like_GTPase" ]

[ 1396 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1396 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 3, 2, 2, 4 ]

4

true

Family

Small GTPase Arf-like protein

Arf-like_GTPase

7

IPR053255

53,255

Epidermal growth factor-like domain-containing protein

EGF-like_domain

Family

1,466

true

false

This family of proteins is involved in the innate immune response by recognizing and binding to lipopolysaccharides on the cell walls of Gram-negative bacteria. They act as pattern recognition receptors, promoting bacterial aggregation and enhancing bacterial clearance. These proteins specifically interact with the inn...

[]

0

[ "PANTHER" ]

[ "PTHR24047" ]

[ "EGF-like_domain" ]

[ 1466 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1466 ]

1

[ "Drosophila melanogaster" ]

[ 43 ]

1

true

Family

Epidermal growth factor-like domain-containing protein

EGF-like_domain

5

IPR053256

53,256

Kelch repeat-containing protein

Kelch_repeat-containing

Family

1,459

true

false

This family of proteins features the kelch motif, which typically forms a beta-propeller structure. These structures are known to mediate a variety of protein-protein interactions. Members of this family are involved in diverse cellular processes, including but not limited to, cytoskeleton organization, cellular morpho...

[]

0

[ "PANTHER" ]

[ "PTHR46773" ]

[ "Kelch_repeat-containing" ]

[ 1459 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Marseillevirus LCMAC103", "marine metagenome" ]

[ 138, 1317, 1, 3 ]

4

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 8, 7, 15 ]

3

true

Family

Kelch repeat-containing protein

Kelch_repeat-containing

2

IPR053259

53,259

Golvesin-related Golgi apparatus protein

Golvesin-related_Golgi

Family

1,187

true

false

This family of proteins includes Golvesin, which is known to be involved in the biogenesis and function of Golgi apparatus. Golvesin is a membrane protein that may play a role in the transport of proteins between different compartments of the Golgi or in the maintenance of Golgi structure. It may also be implicated in ...

[]

0

[ "PANTHER" ]

[ "PTHR32301" ]

[ "Golvesin-related_Golgi" ]

[ 1187 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "metagenomes" ]

[ 3, 334, 841, 9 ]

4

[]

0

true

Family

Golvesin-related Golgi apparatus protein

Golvesin-related_Golgi

6

IPR053262

53,262

ArsA ATPase-like

ArsA_ATPase-like

Family

997

true

false

This family of proteins is associated with ATPase activity and is involved in the transport of various substances across cellular membranes. Members of this family are typically characterized by their ability to hydrolyze ATP to drive the active transport of ions, such as arsenite, antimonite, and other substrates, whi...

[]

0

[ "PANTHER" ]

[ "PTHR43868" ]

[ "ArsA_ATPase-like" ]

[ 997 ]

1

[]

0

[ "3igf", "8egk", "8elf" ]

3

[]

0

[]

0

null

[ "Candidatus Korarchaeum cryptofilum", "Cyanobacteriota", "Viridiplantae" ]

[ 2, 342, 653 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 3, 6 ]

3

true

Family

ArsA ATPase-like

ArsA_ATPase-like

7

IPR053263

53,263

Eukaryotic RPA34 RNA polymerase subunit

Euk_RPA34_RNAP_subunit

Family

1,276

true

false

This family of proteins includes subunits of eukaryotic DNA-directed RNA polymerase I, which are involved in the transcription of DNA into RNA. They play a role in the synthesis of ribosomal RNA precursors and possess intrinsic RNA cleavage activity. Members of this family, such as the heterodimer formed by RPA34 and R...

[]

0

[ "PANTHER" ]

[ "PTHR28155" ]

[ "Euk_RPA34_RNAP_subunit" ]

[ 1276 ]

1

[]

0

[ "4c2m", "4c3h", "4c3i", "4c3j", "4ym7", "5g5l", "5lmx", "5m3f", "5m3m", "5m5w", "5m5x", "5m5y", "5m64", "5n5y", "5n5z", "5n60", "5n61", "5oa1", "5w5y", "5w64", "5w65", "5w66", "6h67", "6h68", "6hko", "6rqh", "6rql", "6rqt", "6rrd", "6rui", "6ruo", "6rwe"...

39

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1276 ]

1

[ "Danio rerio", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1, 1, 1 ]

3

true

Family

Eukaryotic RPA34 RNA polymerase subunit

Euk_RPA34_RNAP_subunit

8

IPR053264

53,264

Inactive lipoate--protein ligase 2

Lipoate-ligase_2_inactive

Family

1,216

true

false

The Inactive lipoate--protein ligase 2 family is involved in the mitochondrial lipoylation process, which is essential for the proper functioning of key dehydrogenase complexes involved in metabolic pathways. Specifically, members of this family work in conjunction with LipL1 to facilitate the lipoylation of the E2 com...

[]

0

[ "PANTHER" ]

[ "PTHR43506" ]

[ "Lipoate-ligase_2_inactive" ]

[ 1216 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 179, 1030, 7 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 8, 3, 5 ]

3

true

Family

Inactive lipoate--protein ligase 2

Lipoate-ligase_2_inactive

8

IPR053265

53,265

Serine protease inhibitor

Serpin

Family

1,273

true

false

This family of proteins includes inhibitors of serine proteases such as human tryptase, trypsin, and chymotrypsin. These inhibitors are likely involved in modulating host defense mechanisms by blocking the activity of these proteases, which play a role in immune responses and other physiological processes.

[]

0

[ "PANTHER" ]

[ "PTHR21131" ]

[ "Serpin" ]

[ 1273 ]

1

[]

0

[ "1an1", "1ldt", "1y1c", "2erw", "2kmo", "2kmp", "2kmq", "2kmr", "5dae", "7e50" ]

10

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "marine metagenome" ]

[ 393, 878, 2 ]

3

[ "Drosophila melanogaster" ]

[ 1 ]

1

true

Family

Serine protease inhibitor

Serpin

4

IPR053266

53,266

Zinc finger protein 7

Zinc_finger_protein_7

Family

1,387

true

false

The Zinc finger protein 7 family is characterized by its role as a negative regulator of abscisic acid signaling during germination and early seedling development. Abscisic acid (ABA) is a plant hormone that plays a crucial role in stress responses and developmental processes. Members of the Zinc finger protein 7 famil...

[]

0

[ "PANTHER" ]

[ "PTHR47593" ]

[ "Zinc_finger_protein_7" ]

[ 1387 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Tracheophyta" ]

[ 1387 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 7, 23 ]

3

true

Family

Zinc finger protein 7

Zinc_finger_protein_7

5

IPR053267

53,267

Verrucosidin biosynthesis-associated protein

Verrucosidin_biosynth-assoc

Family

1,207

true

false

This family of proteins is involved in the biosynthesis of verrucosidin, a neurotoxic compound that disrupts oxidative phosphorylation in mitochondria, leading to neurological diseases. The proteins in this family are part of a gene cluster responsible for the production of verrucosidin's carbon backbone, which is init...

[]

0

[ "PANTHER" ]

[ "PTHR42087" ]

[ "Verrucosidin_biosynth-assoc" ]

[ 1207 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1207 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Family

Verrucosidin biosynthesis-associated protein

Verrucosidin_biosynth-assoc

5

IPR053268

53,268

Woronin body anchoring protein

Woronin_anchor

Family

1,207

true

false

This family of proteins includes tethering components that are crucial for the localization and function of Woronin bodies, which are organelles in certain fungi. Members of this family are involved in the cellular response to hyphal damage by facilitating the occlusion of septal pores, thereby compartmentalizing and p...

[]

0

[ "PANTHER" ]

[ "PTHR40641" ]

[ "Woronin_anchor" ]

[ 1207 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1207 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 4 ]

1

true

Family

Woronin body anchoring protein

Woronin_anchor

2

IPR053269

53,269

L-aspartate--L-methionine ligase

Asp-Met_ligase

Family

1,076

true

This entry includes L-amino acid ligases that catalyse the ATP-dependent formation of dipeptides, specifically L-aspartyl-L-methionine. They exhibit substrate specificity, showing higher activity with L-aspartate and L-methionine, and reduced activity with other amino acid combinations. These enzymes do not function wi...

[]

0

[ "PANTHER" ]

[ "PTHR37018" ]

[ "Asp-Met_ligase" ]

[ 1076 ]

1

[]

0

[ "7r8p", "7r8q" ]

2

[ "PUB00162122" ]

[ "35988643" ]

[ "Discovery of an ʟ-amino acid ligase implicated in Staphylococcal sulfur amino acid metabolism." ]

[ 2022 ]

1

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 468, 605, 3 ]

3

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)" ]

[ 1 ]

1

true

Family

L-aspartate--L-methionine ligase

Asp-Met_ligase

5

IPR053270

53,270

Friend virus susceptibility protein 1

Fv1_restriction_factor

Family

1,970

true

false

The Friend virus susceptibility protein 1 family comprises retroviral restriction factors that protect against infection by gammaretroviruses. Members of the family function by binding to the viral capsid protein post-entry into the host cell. This binding is believed to disrupt the viral capsid, leading to inactivatio...

[]

0

[ "PANTHER" ]

[ "PTHR48195" ]

[ "Fv1_restriction_factor" ]

[ 1970 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1970 ]

1

[ "Mus musculus", "Rattus norvegicus" ]

[ 19, 5 ]

2

true

Family

Friend virus susceptibility protein 1

Fv1_restriction_factor

1

IPR053271

53,271

DDT domain-containing protein

DDT_domain

Family

1,278

true

false

This family of proteins includes members that contain a DDT domain, which is typically associated with DNA-binding properties. The DDT domain is characterized by a conserved pattern of cysteine and histidine residues that coordinate a zinc ion, facilitating the domain's role in binding to DNA. Proteins with this domain...

[]

0

[ "PANTHER" ]

[ "PTHR15546" ]

[ "DDT_domain" ]

[ 1278 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1278 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 7, 10, 13 ]

3

true

Family

DDT domain-containing protein

DDT_domain

1

IPR053272

53,272

Serine/threonine/tyrosine-interacting-like protein

STY_interacting-like

Family

1,214

true

false

This family of proteins includes catalytically inactive phosphatases that interact with specific binding partners to modulate cellular processes. Members of this family are known to bind to G3BP1, a process that results in the inhibition of stress granule formation. These proteins do not prevent the dephosphorylation o...

[]

0

[ "PANTHER" ]

[ "PTHR46659" ]

[ "STY_interacting-like" ]

[ 1214 ]

1

[]

0

[ "9d2f", "9fqr" ]

2

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1214 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 4, 6, 5, 7 ]

4

true

Family

Serine/threonine/tyrosine-interacting-like protein

STY_interacting-like

4

IPR053273

53,273

Cell_Separation_Timing_Regulator

CST_Regulator

Family

1,498

true

false

This family of proteins appears to play a role in the process of cytokinesis, specifically in the timing of cell separation. Members of this family may function either as enzymes involved in the degradation of glucans within the cell wall at the neck region between mother and daughter cells, or as regulatory proteins t...

[]

0

[ "PANTHER" ]

[ "PTHR34659" ]

[ "CST_Regulator" ]

[ 1498 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1498 ]

1

[ "Arabidopsis thaliana", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 21, 1 ]

2

true

Family

Cell_Separation_Timing_Regulator

CST_Regulator

2

IPR053274

53,274

Fluconazole resistance-associated protein

Fluconazole_resistance

Family

1,163

true

false

This family of proteins is associated with a phenotype resistant to the antifungal drug fluconazole when deleted. The exact molecular function of these proteins remains to be characterized, but the observed resistance suggests a potential role in the cellular mechanisms that contribute to antifungal drug susceptibility...

[]

0

[ "PANTHER" ]

[ "PTHR28065" ]

[ "Fluconazole_resistance" ]

[ 1163 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1163 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1, 1 ]

2

true

Family

Fluconazole resistance-associated protein

Fluconazole_resistance

4

IPR053276

53,276

Mitochondrial DNA mismatch repair MutS

MtDNA_mismatch_repair_MutS

Family

1,369

true

DNA mismatch repair MutS is involved in the maintenance of mitochondrial genome integrity. Members of this family, such as MSH1 from Arabidopsis thaliana, play a crucial role in controlling mitochondrial genome configuration. They achieve this by suppressing asymmetric recombination at certain repeat pairs, thereby pre...

[]

0

[ "PANTHER" ]

[ "PTHR48448" ]

[ "" ]

[ 1369 ]

1

[]

0

[]

0

[ "PUB00155247", "PUB00155248", "PUB00155249", "PUB00155250" ]

[ "19822729", "20139171", "16830098", "12730382" ]

[ "Diversity of the Arabidopsis mitochondrial genome occurs via nuclear-controlled recombination activity.", "Extensive rearrangement of the Arabidopsis mitochondrial genome elicits cellular conditions for thermotolerance.", "Mitochondrial genome dynamics in plants and animals: convergent gene fusions of a MutS h...

[ 2009, 2010, 2006, 2003 ]

4

[]

0

null

[ "Candidatus Endobugula sertula", "Eukaryota" ]

[ 2, 1367 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 5, 6, 22 ]

3

true

Family

Mitochondrial DNA mismatch repair MutS

MtDNA_mismatch_repair_MutS

3

IPR053277

53,277

Endomembrane trafficking modulator

Endomembrane_traffic_mod

Family

1,176

true

false

This family of proteins is involved in endomembrane trafficking, specifically in the recycling of proteins to the plasma membrane. Members of this family form a complex with other proteins and actin, which is crucial for the modulation of the trans-Golgi network and early endosome functions. These proteins are also imp...

[]

0

[ "PANTHER" ]

[ "PTHR45005" ]

[ "Endomembrane_traffic_mod" ]

[ 1176 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Methanomicrobia", "metagenomes" ]

[ 100, 1057, 2, 17 ]

4

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 6, 5, 13 ]

3

true

Family

Endomembrane trafficking modulator

Endomembrane_traffic_mod

6

IPR053278

53,278

Shuttling pre-60S factor ECM1

Pre-60S_factor_ECM1

Family

1,129

true

false

This family of proteins is involved in the nucleocytoplasmic transport process, specifically in the export of the 60S ribosomal subunit from the nucleus. Members of this family function as pre-ribosomal factors that are essential for the proper assembly and maturation of the 60S subunit, which is a critical component o...

[]

0

[ "PANTHER" ]

[ "PTHR28280" ]

[ "Pre-60S_factor_ECM1" ]

[ 1129 ]

1

[]

0

[ "8hfr" ]

1

[]

0

[]

0

null

[ "Dikarya" ]

[ 1129 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1, 1 ]

2

true

Family

Shuttling pre-60S factor ECM1

Pre-60S_factor_ECM1

1

IPR053279

53,279

ER membrane protein complex subunit

EMC_subunit

Family

1,056

true

false

This family of proteins is involved in the biogenesis and insertion of membrane proteins into the endoplasmic reticulum (ER). Members facilitate the energy-independent integration of newly synthesized proteins into the ER membrane, particularly accommodating those with less hydrophobic or destabilizing transmembrane do...

[]

0

[ "PANTHER" ]

[ "PTHR28144" ]

[ "EMC_subunit" ]

[ 1056 ]

1

[]

0

[ "6wb9", "7kra", "7ktx" ]

3

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1056 ]

1

[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]

[ 1, 1 ]

2

true

Family

ER membrane protein complex subunit

EMC_subunit

5

IPR053280

53,280

Aerolysin-like pore-forming protein

Aerolysin-like_pore-former

Family

1,086

true

false

This family of proteins includes pore-forming proteins that may have a role in host defense mechanisms. They are capable of forming dimers and can also oligomerize into octameric structures that span the cell membrane. The oligomerization process is likely initiated by the binding of a jacalin-type lectin domain to spe...

[]

0

[ "PANTHER" ]

[ "PTHR34007" ]

[ "Aerolysin-like_pore-former" ]

[ 1086 ]

1

[]

0

[ "4zno", "4znq", "4znr", "5di0", "5zu4", "6iul" ]

6

[]

0

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 36, 1050 ]

2

[ "Caenorhabditis elegans", "Danio rerio" ]

[ 5, 32 ]

2

true

Family

Aerolysin-like pore-forming protein

Aerolysin-like_pore-former

7

IPR053281

53,281

Double zinc ribbon domain-containing protein

Double_zinc_ribbon

Family

799

true

false

This family of proteins includes members that are characterized by the presence of a double zinc ribbon motif. The double zinc ribbon is a type of zinc finger domain that typically binds two zinc ions and is involved in protein-protein and protein-DNA interactions. Proteins with this motif are often involved in transcr...

[]

0

[ "PANTHER" ]

[ "PTHR36718" ]

[ "Double_zinc_ribbon" ]

[ 799 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Methanobacteriota", "bioreactor metagenome" ]

[ 327, 433, 33, 6 ]

4

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 2, 3, 1 ]

3

true

Family

Double zinc ribbon domain-containing protein

Double_zinc_ribbon

1

IPR053282

53,282

Regulator of G-protein signaling domain-containing protein

RGS_domain-containing

Family

1,095

true

false

This family of proteins includes regulators that modulate the activity of G-proteins, which are molecular switches involved in transmitting signals from various stimuli outside a cell to its interior. Their primary function is to inactivate G-proteins by accelerating the hydrolysis of GTP to GDP, thereby terminating th...

[]

0

[ "PANTHER" ]

[ "PTHR47079" ]

[ "RGS_domain-containing" ]

[ 1095 ]

1

[ "REACTOME", "REACTOME", "REACTOME" ]

[ "R-HSA-416476", "R-HSA-418594", "R-HSA-418597" ]

[ "REACTOME:R-HSA-416476", "REACTOME:R-HSA-418594", "REACTOME:R-HSA-418597" ]

3

[]

0

[]

0

[]

0

null

[ "Metazoa" ]

[ 1095 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 29, 9, 5, 6 ]

4

true

Family

Regulator of G-protein signaling domain-containing protein

RGS_domain-containing

8

IPR053284

53,284

RGS1-HXK1-interacting protein

RGS1-HXK1_interactor

Family

1,355

true

This entry represents RGS1-HXK1-interacting protein 1 found in Arabidopsis thaliana and similar proteins found in plant. RHIP1 provides a physical connection between the glucose signaling sensors RGS1 and HXK1, and is required for some glucose-regulated gene expression in plants [ ].

[]

0

[ "PFAM", "PANTHER" ]

[ "PF27724", "PTHR34554" ]

[ "RHIP1", "RGS1-HXK1_interactor" ]

[ 1353, 1321 ]

2

[]

0

[]

0

[ "PUB00089257" ]

[ "26528314" ]

[ "Cooperative control between AtRGS1 and AtHXK1 in a WD40-repeat protein pathway in Arabidopsis thaliana." ]

[ 2015 ]

1

[]

[ "IPR016803" ]

0

1

0

[ "Eukaryota" ]

[ 1355 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 5, 5, 7 ]

3

true

Family

RGS1-HXK1-interacting protein

RGS1-HXK1_interactor

4

IPR053285

53,285

Thylakoid lumenal pentapeptide repeat protein

Thylakoid_lumenal_pentapeptide

Family

1,087

true

false

This family of proteins includes thylakoid lumenal components that are characterized by the presence of pentapeptide repeats. The precise biological functions of these proteins remain unclear, but they are known to be susceptible to degradation in their reduced form. The proteins may play a role in the thylakoid lumen ...

[]

0

[ "PANTHER" ]

[ "PTHR47121" ]

[ "Thylakoid_lumenal_pentapeptide" ]

[ 1087 ]

1

[]

0

[ "7muc", "7mue", "7muq", "7mus", "7muv", "7muw", "7muy", "9ngv", "9ngw", "9ngy", "9nh0" ]

11

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "marine sediment metagenome" ]

[ 230, 856, 1 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 8, 2, 3 ]

3

true

Family

Thylakoid lumenal pentapeptide repeat protein

Thylakoid_lumenal_pentapeptide

2

IPR053286

53,286

Nematode receptor-like srab

Nematode_rcpt-like_srab

Family

1,168

true

false

This family of proteins includes receptors that are likely to be involved in chemosensory processes. They are characterized by a serpentine topology, typically with multiple transmembrane domains, which suggests a role in signal transduction. These receptors may be responsible for detecting environmental cues and initi...

[]

0

[ "PANTHER" ]

[ "PTHR46561" ]

[ "Nematode_rcpt-like_srab" ]

[ 1168 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bilateria" ]

[ 1168 ]

1

[ "Caenorhabditis elegans" ]

[ 28 ]

1

true

Family

Nematode receptor-like srab

Nematode_rcpt-like_srab

8

IPR053287

53,287

PP2C-like domain-containing protein

PP2C-like_domain

Family

1,022

true

false

This family of proteins includes phosphatase 2C-like enzymes, which are characterized by their ability to dephosphorylate serine and threonine residues in target substrates. These enzymes play a crucial role in various cellular processes, including cell cycle regulation, stress response, and signal transduction pathway...

[]

0

[ "PANTHER" ]

[ "PTHR21586" ]

[ "PP2C-like_domain" ]

[ 1022 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 19, 1003 ]

2

[ "Caenorhabditis elegans", "Drosophila melanogaster" ]

[ 2, 2 ]

2

true

Family

PP2C-like domain-containing protein

PP2C-like_domain

8

IPR053288

53,288

TRIGALACTOSYLDIACYLGLYCEROL Bridge Protein

TGD_Bridge_Protein

Family

1,312

true

false

This family of proteins is involved in lipid trafficking within plant cells, specifically facilitating the movement of lipids from the outer to the inner envelope of plastids. Members of this family play a critical role in the assembly of thylakoid lipids by acting as a bridge between the TGD4 protein and the TGD1,2,3 ...

[]

0

[ "PANTHER" ]

[ "PTHR34201" ]

[ "TGD_Bridge_Protein" ]

[ 1312 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1312 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 6, 7, 13 ]

3

true

Family

TRIGALACTOSYLDIACYLGLYCEROL Bridge Protein

TGD_Bridge_Protein

8

IPR053290

53,290

TSET complex member

TSET_complex_member

Family

1,142

true

false

This family of proteins is involved in the TSET complex, which is implicated in the transport of transmembrane proteins. Members of this family, such as TstF, are likely to play a role in the assembly or function of this complex, contributing to the intracellular trafficking processes that are essential for cellular fu...

[]

0

[ "PANTHER" ]

[ "PTHR45521" ]

[ "TSET_complex_member" ]

[ 1142 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1142 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 10, 10, 54 ]

3

true

Family

TSET complex member

TSET_complex_member

2

IPR053292

53,292

UBAP1-MVB12-associated (UMA)-domain containing protein 1

UMAD1

Family

1,041

false

This family of proteins includes the human UBAP1-MVB12-associated (UMA)-domain containing protein 1 (UMAD1) and related proteins that contain an UMA domain. This domain is associated with the UBAP1-MVB12 complex. A key aspect of eukaryotic intracellular trafficking is the sorting of cell-surface proteins into multi-ves...

[]

0

[ "PFAM", "PANTHER" ]

[ "PF28191", "PTHR36291" ]

[ "UBAP1-MVB12_assoc", "" ]

[ 1040, 926 ]

2

[]

0

[]

0

[ "PUB00054220" ]

[ "20448139" ]

[ "UMA and MABP domains throw light on receptor endocytosis and selection of endosomal cargoes." ]

[ 2010 ]

1

[]

0

null

[ "Eumetazoa" ]

[ 1041 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 2, 5, 6, 4 ]

4

true

Family

UBAP1-MVB12-associated (UMA)-domain containing protein 1

UMAD1

9

IPR053294

53,294

RNA-binding PWI domain-containing protein

RBM_PWI_domain

Family

1,167

true

false

This family of proteins includes RNA-binding regulators involved in the modulation of alternative pre-mRNA splicing. Members of this family are characterized by the presence of a PWI domain, which is known to bind nucleic acids and is instrumental in the protein's role in splicing regulation. The PWI domain's affinity ...

[]

0

[ "PANTHER" ]

[ "PTHR47334" ]

[ "RBM_PWI_domain" ]

[ 1167 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1167 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 8, 5, 27 ]

3

true

Family

RNA-binding PWI domain-containing protein

RBM_PWI_domain

6

IPR053295

53,295

Innate immunity regulator

Innate_immunity_reg

Family

887

true

false

This family of proteins is involved in the innate immune response, likely through interaction with the atf-7 signaling pathway. Members of this family are implicated in providing resistance against pathogenic bacterial infections. Additionally, they may have a regulatory role in determining the lifespan of an organism.

[]

0

[ "PANTHER" ]

[ "PTHR47324" ]

[ "Innate_immunity_reg" ]

[ 887 ]

1

[]

0

[ "1wk1" ]

1

[]

0

[]

0

null

[ "Nematoda" ]

[ 887 ]

1

[ "Caenorhabditis elegans" ]

[ 9 ]

1

true

Family

Innate immunity regulator

Innate_immunity_reg

2

IPR053296

53,296

TSET complex member tstB

TSET_member_tstB

Family

1,073

true

false

This family of proteins is involved in the formation of the TSET complex, which plays a role in cellular processes. The specific functions of the TSET complex and its member tstB are not fully characterized, but they are believed to be important for the proper functioning of the cell. Proteins in this family may have r...

[]

0

[ "PANTHER" ]

[ "PTHR48151" ]

[ "TSET_member_tstB" ]

[ 1073 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 1073 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 8, 6, 26 ]

3

true

Family

TSET complex member tstB

TSET_member_tstB

4

IPR053297

53,297

Dynactin-associated protein

Dynactin-associated

Family

495

true

false

This family of proteins is involved in the regulation of cellular proliferation. Members of this family are known to enhance the activation of the AKT1 signaling pathway, which is crucial for various cellular processes including metabolism, growth, and survival. They are also implicated in facilitating the phosphorylat...

[]

0

[ "PANTHER" ]

[ "PTHR35349" ]

[ "Dynactin-associated" ]

[ 495 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Candidatus Protochlamydia naegleriophila", "Eukaryota" ]

[ 1, 494 ]

2

[ "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 2, 2, 3 ]

3

true

Family

Dynactin-associated protein

Dynactin-associated

9

IPR053298

53,298

Sushi domain-containing protein

Sushi_domain_protein

Family

822

true

false

This family of proteins is characterized by the presence of sushi domains, which are also known as complement control protein (CCP) modules. Sushi domains are found in a variety of extracellular and membrane-bound proteins and are typically involved in protein-protein interactions. They play a role in a wide range of b...

[]

0

[ "PANTHER" ]

[ "PTHR32493" ]

[ "Sushi_domain_protein" ]

[ 822 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Vertebrata" ]

[ 822 ]

1

[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]

[ 1, 3, 1, 2 ]

4

true

Family

Sushi domain-containing protein

Sushi_domain_protein

5

IPR053299

53,299

ASTRA complex-associated WD repeat

ASTRA_WD_repeat

Family

1,674

true

false

This family of proteins is involved in the structural organization of chromatin. Members of this family are components of the ASTRA complex, which plays a role in chromatin remodeling. Chromatin remodeling is a dynamic process that allows the regulation of gene expression by altering the chromatin structure, thereby ma...

[]

0

[ "PANTHER" ]

[ "PTHR44156" ]

[ "ASTRA_WD_repeat" ]

[ 1674 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "metagenomes" ]

[ 175, 1497, 2 ]

3

[ "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Mus musculus", "Zea mays" ]

[ 1, 1, 1, 1, 3 ]

5

true

Family

ASTRA complex-associated WD repeat

ASTRA_WD_repeat

2

IPR053300

53,300

Homeobox-like transcriptional regulator

Homeobox-like_regulator

Family

983

true

false

This family of proteins includes transcriptional regulators that interact with specific DNA motifs to control gene expression. They play a crucial role in the early stages of gametocyte development by binding to distinct DNA sequences, thereby regulating genes vital for the growth of the inner membrane complex, which i...

[]

0

[ "PANTHER" ]

[ "PTHR45795" ]

[ "Homeobox-like_regulator" ]

[ 983 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "viral metagenome" ]

[ 24, 958, 1 ]

3

[]

0

true

Family

Homeobox-like transcriptional regulator

Homeobox-like_regulator

7

IPR053301

53,301

F-box motif-containing protein

F-box_motif

Family

1,039

true

false

This family of proteins is characterized by the presence of an F-box motif, which is typically involved in protein-protein interactions. Members of this family are known to play crucial roles in the ubiquitin-proteasome pathway. They function as part of the SCF (SKP1-CUL1-F-box protein) complex, acting as substrate-rec...

[]

0

[ "PANTHER" ]

[ "PTHR45088" ]

[ "F-box_motif" ]

[ 1039 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "ecological metagenomes" ]

[ 289, 745, 5 ]

3

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 5, 3, 8 ]

3

true

Family

F-box motif-containing protein

F-box_motif

5

IPR053303

53,303

Chloroplast PPR-containing protein

Chloroplast_PPR

Family

956

true

false

This family of proteins includes regulators involved in the post-transcriptional modification of chloroplast transcripts, particularly those related to the large subunit of RuBisCO, a key enzyme in the photosynthetic carbon fixation process. Members of this family are thought to play a role in either the processing or ...

[]

0

[ "PANTHER" ]

[ "PTHR47935" ]

[ "Chloroplast_PPR" ]

[ 956 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 956 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 5, 9, 12 ]

3

true

Family

Chloroplast PPR-containing protein

Chloroplast_PPR

8

IPR053304

53,304

RNA M5U Methyltransferase

RNA_M5U_MTase

Family

874

true

false

This family of proteins includes RNA methyltransferases that are characterized by their similarity to the class I-like SAM-binding methyltransferase superfamily. Members of this family are involved in the methylation of the 5th carbon of uridine residues in RNA molecules, a modification that can affect the stability, s...

[]

0

[ "PANTHER" ]

[ "PTHR47548" ]

[ "RNA_M5U_MTase" ]

[ 874 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 7, 867 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 4, 5 ]

3

true

Family

RNA M5U Methyltransferase

RNA_M5U_MTase

3

IPR053305

53,305

Folate-binding receptor-like

Folate-binding_rcpt-like

Family

912

true

false

This family of proteins is involved in the binding and transport of folic acid, a vital nutrient. Members are implicated in the uptake and accumulation of folic acid within cells, particularly in response to salicylic acid-induced signals. They may play a role in the distribution of folates, facilitating their movement...

[]

0

[ "PANTHER" ]

[ "PTHR37390" ]

[ "Folate-binding_rcpt-like" ]

[ 912 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 912 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 9, 3, 7 ]

3

true

Family

Folate-binding receptor-like

Folate-binding_rcpt-like

9

IPR053307

53,307

Mitochondrial ATP-independent inner membrane protease

Mitochondrial_IM_protease

Family

936

true

false

This family of proteins is involved in the processing of mitochondrial precursor proteins. Members of this family function as ATP-independent proteases located within the inner membrane of mitochondria. They are responsible for the cleavage of transit peptides from precursor proteins during their translocation into the...

[]

0

[ "PANTHER" ]

[ "PTHR47040" ]

[ "Mitochondrial_IM_protease" ]

[ 936 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 936 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 11, 2, 17 ]

3

true

Family

Mitochondrial ATP-independent inner membrane protease

Mitochondrial_IM_protease

6

IPR053308

53,308

Vago-like

Family

817

false

This family includes a group of proteins from arthropods that contain the single domain Von Willebrand factor type C ( ), including Protein Vago from Drosophila melanogaster, which is likely to play a significant role in the immune response against viral infections [ ], and the toxin U-scoloptoxin(16)-Ssd1a from Scolop...

[]

0

[ "PANTHER" ]

[ "PTHR39957" ]

[ "" ]

[ 817 ]

1

[]

0

[]

0

[ "PUB00155203", "PUB00155204" ]

[ "18953338", "24847043" ]

[ "The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila.", "Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (centipedes)." ]

[ 2008, 2014 ]

2

[]

0

null

[ "Arthropoda" ]

[ 817 ]

1

[ "Drosophila melanogaster" ]

[ 11 ]

1

true

Family

Vago-like

5

IPR053309

53,309

Balbiani Body Formation Protein

Balbiani_Body_Formation

Family

771

true

false

This family of proteins is involved in the early stages of oocyte development, specifically in the formation of the Balbiani body and germ plasm assembly. Members of this family exhibit prion-like characteristics that are essential for establishing oocyte polarity during oogenesis. They interact with tudor domain-conta...

[]

0

[ "PANTHER" ]

[ "PTHR38654" ]

[ "Balbiani_Body_Formation" ]

[ 771 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Gnathostomata" ]

[ 771 ]

1

[ "Danio rerio" ]

[ 2 ]

1

true

Family

Balbiani Body Formation Protein

Balbiani_Body_Formation

8

IPR053310

53,310

Flavoredoxin-like

Family

270

true

false

This family of proteins is involved in redox reactions, where they participate in the transfer of electrons. Members of this family typically contain a flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD) as a cofactor, which is essential for their catalytic activity. These proteins play a role in various b...

[]

0

[ "PANTHER" ]

[ "PTHR43241" ]

[ "Flavoredoxin-like" ]

[ 270 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Archaea", "Bacteria", "Eukaryota", "metagenomes" ]

[ 31, 103, 126, 10 ]

4

[]

0

true

Family

Flavoredoxin-like

5

IPR053313

53,313

Root Meristem Growth Factor

RGF

Family

921

true

false

This family of proteins is involved in the maintenance of the postembryonic root stem cell niche in plants. They play a crucial role in regulating the expression levels and spatial patterns of key transcription factors that are essential for root development. Members of this family are particularly important for the mo...

[]

0

[ "PANTHER" ]

[ "PTHR34961" ]

[ "RGF" ]

[ 921 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Magnoliopsida" ]

[ 921 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 4, 4 ]

3

true

Family

Root Meristem Growth Factor

RGF

6

IPR053315

53,315

Peptidase C14A

Peptidase_C14A

Family

598

true

false

This family of proteins includes cysteine proteases that play a role in apoptosis and cellular homeostasis. Members are characterized by their ability to cleave themselves and other caspase proteins into active forms. They are involved in the programmed cell death of certain cells during embryogenesis and can be regula...

[]

0

[ "PANTHER" ]

[ "PTHR23362" ]

[ "Peptidase_C14A" ]

[ 598 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Caenorhabditis" ]

[ 598 ]

1

[ "Caenorhabditis elegans" ]

[ 41 ]

1

true

Family

Peptidase C14A

Peptidase_C14A

2

IPR053318

53,318

Glycosyltransferase 64

GT64

Family

1,386

false

Glycosyltransferase 64 (GT64) is involved in the biosynthesis of glycosylinositol phosphorylceramides (GIPCs) and is thought to be essential for cell-cell adhesion, organ integrity, and metabolite movement in plants [ ]. Members of the family, such as Glycosylinositol phosphorylceramide mannosyl transferase 1, function...

[]

0

[ "PANTHER", "PANTHER" ]

[ "PTHR48409", "PTHR48410" ]

[ "", "" ]

[ 502, 884 ]

2

[]

0

[]

0

[ "PUB00072935", "PUB00155268", "PUB00155269", "PUB00155270" ]

[ "16045474", "20687615", "27895225", "17426055" ]

[ "Cell adhesion in Arabidopsis thaliana is mediated by ECTOPICALLY PARTING CELLS 1--a glycosyltransferase (GT64) related to the animal exostosins.", "Identification of novel proteins involved in plant cell-wall synthesis based on protein-protein interaction data.", "Loss of Inositol Phosphorylceramide Sphingolip...

[ 2005, 2010, 2016, 2007 ]

4

[]

0

null

[ "Eukaryota" ]

[ 1386 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 9, 5, 6 ]

3

true

Family

Glycosyltransferase 64

GT64

8

IPR053319

53,319

Outer envelope protein 61

OEP61

Family

905

false

Outer envelope protein 61 is involved in protein import into the endoplasmic reticulum and chloroplasts. It is thought to act as chaperone docking proteins during post-translational protein translocation into the ER. It also implicated in chaperone-mediated targeting of proteins to chloroplasts, interacting specificall...

[]

0

[ "PANTHER" ]

[ "PTHR48433" ]

[ "" ]

[ 905 ]

1

[]

0

[]

0

[ "PUB00125593", "PUB00155241" ]

[ "21612577", "22899711" ]

[ "OEP61 is a chaperone receptor at the plastid outer envelope.", "AtTPR7 is a chaperone-docking protein of the Sec translocon in Arabidopsis." ]

[ 2011, 2012 ]

2

[]

0

null

[ "Eukaryota" ]

[ 905 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 6, 3 ]

3

true

Family

Outer envelope protein 61

OEP61

4

IPR053320

53,320

Protein DD3-3 O-glycosylation

Protein_DD3-3_O-glyco

Family

688

true

false

The Protein DD3-3 family is implicated in the biological process of O-glycosylation. Members of this family are believed to play a role in the enzymatic addition of sugar moieties to oxygen atoms on serine or threonine residues of proteins, a post-translational modification critical for protein stability, localization,...

[]

0

[ "PANTHER" ]

[ "PTHR35170" ]

[ "Protein_DD3-3_O-glyco" ]

[ 688 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 688 ]

1

[]

0

true

Family

Protein DD3-3 O-glycosylation

Protein_DD3-3_O-glyco

9

IPR053321

53,321

Inositol Polyphosphate 5-Phosphatase Type IV

IPP-5-Phosphatase_Type_IV

Family

698

true

false

This family of proteins is involved in the regulation of phosphoinositide composition within cellular membranes. Members of this family act as enzymes that modify phosphatidylinositol phosphates by removing a phosphate group. Specifically, they convert phosphatidylinositol 3,4,5-trisphosphate to a bisphosphate form and...

[]

0

[ "PANTHER" ]

[ "PTHR47039" ]

[ "IPP-5-Phosphatase_Type_IV" ]

[ 698 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Opisthokonta" ]

[ 698 ]

1

[ "Drosophila melanogaster" ]

[ 1 ]

1

true

Family

Inositol Polyphosphate 5-Phosphatase Type IV

IPP-5-Phosphatase_Type_IV

8

IPR053322

53,322

Phospholipase A2-like

PLA2-like

Family

740

true

false

This family of proteins includes enzymes that hydrolyze glycerophospholipids to produce fatty acids and lysophospholipids. Members of this family typically act at the sn-2 position of phospholipids and release arachidonic acid, a precursor of eicosanoids which are potent mediators of cellular signaling involved in infl...

[]

0

[ "PANTHER" ]

[ "PTHR34228" ]

[ "PLA2-like" ]

[ 740 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 740 ]

1

[ "Caenorhabditis elegans" ]

[ 15 ]

1

true

Family

Phospholipase A2-like

PLA2-like

7

IPR053324

53,324

Hydrophobic Surface Structural Protein

Hydrophobic_Surface_Structural

Family

570

true

false

This family of proteins includes structural components that confer water-repellency to certain surfaces. They play a crucial role in the development of aerial hyphae, which are necessary for filamentous growth in some organisms. The proteins are involved in maintaining surface hydrophobicity, which is essential for the...

[]

0

[ "PANTHER" ]

[ "PTHR48128" ]

[ "Hydrophobic_Surface_Structural" ]

[ 570 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota" ]

[ 14, 556 ]

2

[]

0

true

Family

Hydrophobic Surface Structural Protein

Hydrophobic_Surface_Structural

4

IPR053325

53,325

Histone H3 Acetylation Activator

H3-Acetyl_Activator

Family

776

true

false

This family of proteins is involved in the regulation of gene expression. Members of this family are known to activate transcription by interacting with the histone acetyltransferase HAG1/GCN5. This interaction leads to the acetylation of histone H3 at the promoters of target genes, which is a key epigenetic modificati...

[]

0

[ "PANTHER" ]

[ "PTHR35706" ]

[ "H3-Acetyl_Activator" ]

[ 776 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 776 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 2, 2, 4 ]

3

true

Family

Histone H3 Acetylation Activator

H3-Acetyl_Activator

6

IPR053326

53,326

G-protein coupled receptor 1-like

GPCR1-like

Family

616

true

false

This family of proteins includes receptors that are typically part of the G-protein coupled receptor (GPCR) superfamily. GPCRs are characterized by their seven transmembrane domains and are involved in transmitting signals from the extracellular environment to the interior of the cell. They play a pivotal role in vario...

[]

0

[ "PANTHER" ]

[ "PTHR47632" ]

[ "GPCR1-like" ]

[ 616 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Protostomia" ]

[ 616 ]

1

[ "Caenorhabditis elegans" ]

[ 7 ]

1

true

Family

G-protein coupled receptor 1-like

GPCR1-like

4

IPR053327

53,327

Kinase-Interacting Protein

KIP

Family

781

true

false

This family of proteins is potentially involved in signal transduction processes mediated by receptor-like kinases. Members of this family may play a role in cellular communication and response mechanisms by interacting with kinase enzymes, which are known to be pivotal in regulating a variety of cellular pathways.

[]

0

[ "PANTHER" ]

[ "PTHR36001" ]

[ "KIP" ]

[ 781 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Tracheophyta" ]

[ 781 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 30, 6, 5 ]

3

true

Family

Kinase-Interacting Protein

KIP

3

IPR053329

53,329

Merozoite Surface-Associated Protein

Merozoite_Surface_Assoc

Family

1,222

true

false

This family of proteins is implicated in the process of merozoite invasion of erythrocytes. Members are believed to be involved in the initial attachment of the merozoite to the erythrocyte surface, which is a critical step in the life cycle of the parasite. Additionally, these proteins possess a region at the N-termin...

[]

0

[ "PANTHER" ]

[ "PTHR39110" ]

[ "Merozoite_Surface_Assoc" ]

[ 1222 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Stenosarchaea group", "Viruses", "metagenomes" ]

[ 46, 1154, 3, 16, 3 ]

5

[ "Arabidopsis thaliana", "Danio rerio", "Oryza sativa subsp. japonica" ]

[ 10, 1, 7 ]

3

true

Family

Merozoite Surface-Associated Protein

Merozoite_Surface_Assoc

6

IPR053330

53,330

Mucin-22-like

Family

499

true

false

This family of proteins includes mucin-22, which is a type of glycoprotein typically found in the mucus secreted by epithelial tissues. Mucins are characterized by their high carbohydrate content and are responsible for the gel-like properties of mucus, which serves as a protective barrier against pathogens and helps t...

[]

0

[ "PANTHER" ]

[ "PTHR37000" ]

[ "Mucin-22-like" ]

[ 499 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Mimivirus LCMiAC02" ]

[ 20, 478, 1 ]

3

[ "Homo sapiens" ]

[ 41 ]

1

true

Family

Mucin-22-like

1

IPR053333

53,333

Cytochrome b6-f complex subunit 7

Cytochrome_b6-f_sub7

Family

776

true

false

The PetM family comprises proteins that are components of the cytochrome b6-f complex, which is crucial for photosynthesis in plants and cyanobacteria. Members of the PetM family play a role in mediating electron transfer between photosystem II and photosystem I, facilitating cyclic electron flow around photosystem I, ...

[]

0

[ "PANTHER" ]

[ "PTHR34951" ]

[ "Cytochrome_b6-f_sub7" ]

[ 776 ]

1

[]

0

[ "6rqf", "7qrm", "7zyv", "9es7", "9es8", "9es9" ]

6

[]

0

[]

0

null

[ "Eukaryota", "Marinobacter salinexigens" ]

[ 775, 1 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 4, 2, 6 ]

3

true

Family

Cytochrome b6-f complex subunit 7

Cytochrome_b6-f_sub7

2

IPR053334

53,334

Chloroplast Sensor Kinase

Chloroplast_Sensor_Kinase

Family

680

true

false

This family of proteins is involved in the regulation of photosynthesis in chloroplasts. Members act as sensor kinases that detect changes in the redox state of plastoquinone, which is a key component in the photosynthetic electron transport chain. These proteins play a crucial role in the long-term adaptation of photo...

[]

0

[ "PANTHER" ]

[ "PTHR48206" ]

[ "Chloroplast_Sensor_Kinase" ]

[ 680 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Desertifilum tharense IPPAS B-1220", "Eukaryota" ]

[ 1, 679 ]

2

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 2, 6, 10 ]

3

true

Family

Chloroplast Sensor Kinase

Chloroplast_Sensor_Kinase

1

IPR053335

53,335

Fatty Acid Desaturase CarF-like

Fatty_acid_desaturase_CarF

Family

295

true

false

This family of proteins includes enzymes that are involved in the biosynthesis of unsaturated fatty acids. Members of this family are characterized by their ability to introduce double bonds into fatty acyl chains, a process that is essential for the production of unsaturated fatty acids. These unsaturated fatty acids ...

[]

0

[ "PANTHER" ]

[ "PTHR48230" ]

[ "Fatty_acid_desaturase_CarF" ]

[ 295 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Mimiviridae", "metagenomes" ]

[ 48, 213, 25, 9 ]

4

[ "Caenorhabditis elegans" ]

[ 1 ]

1

true

Family

Fatty Acid Desaturase CarF-like

Fatty_acid_desaturase_CarF

7

IPR053336

53,336

Rhoptry Surface-Associated Protein

Rhoptry_Surface_Assoc

Family

587

true

false

This family of proteins is involved in the critical process of merozoite invasion into host erythrocytes. Members of this family are associated with the rhoptry, an organelle found in the apicomplexan parasites, and contribute to the proper functioning of rhoptry structures and mechanisms. The activity of these protein...

[]

0

[ "PANTHER" ]

[ "PTHR37320" ]

[ "Rhoptry_Surface_Assoc" ]

[ 587 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Caudoviricetes", "Eukaryota", "viral metagenome" ]

[ 154, 4, 428, 1 ]

4

[]

0

true

Family

Rhoptry Surface-Associated Protein

Rhoptry_Surface_Assoc

4

IPR053337

53,337

Autotransporter-2 adhesin

AT-2_adhesin

Family

429

true

false

This family of proteins is involved in bacterial virulence and adherence to human respiratory epithelial cells. Members possess a signal peptide that directs the protein to the periplasmic space and a C-terminal translocator domain that forms a pore in the outer membrane, allowing the passenger domain to reach the bact...

[]

0

[ "PANTHER" ]

[ "PTHR37001" ]

[ "AT-2_adhesin" ]

[ 429 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Bacteria", "Eukaryota", "Viruses", "viral metagenome" ]

[ 16, 410, 2, 1 ]

4

[ "Drosophila melanogaster" ]

[ 1 ]

1

true

Family

Autotransporter-2 adhesin

AT-2_adhesin

6

IPR053339

53,339

FAS1 domain-containing protein

FAS1_domain_protein

Family

635

true

false

This family of proteins includes members that contain a FAS1 domain, which is typically involved in cell adhesion processes. The FAS1 domain is found in a variety of proteins across different species and is known for its role in the formation of adhesive structures. Proteins with this domain may participate in interact...

[]

0

[ "PANTHER" ]

[ "PTHR36069" ]

[ "FAS1_domain_protein" ]

[ 635 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Embryophyta" ]

[ 635 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 11, 2, 3 ]

3

true

Family

FAS1 domain-containing protein

FAS1_domain_protein

6

IPR053340

53,340

Plant-specific TFIIB-related protein PTF2

PTF2

Family

690

false

Plant-specific TFIIB-related protein PTF2 is characterised by its unique role in plant development, particularly in pollen germination and embryogenesis. Members of this family, such as PTF2 from Arabidopsis thaliana, are known to interact with TBP2 and RNA polymerase subunits, suggesting a regulatory function in gene ...

[]

0

[ "PANTHER" ]

[ "PTHR48428" ]

[ "" ]

[ 690 ]

1

[]

0

[]

0

[ "PUB00154397" ]

[ "23713077" ]

[ "Pollen-expressed transcription factor 2 encodes a novel plant-specific TFIIB-related protein that is required for pollen germination and embryogenesis in Arabidopsis." ]

[ 2013 ]

1

[]

0

null

[ "Eukaryota" ]

[ 690 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 3, 6, 3 ]

3

true

Family

Plant-specific TFIIB-related protein PTF2

PTF2

4

IPR053341

53,341

Oxidative Stress Response Globin-like

Oxidative_stress_globin-like

Family

587

true

false

This family of proteins is characterized by its role in the response to oxidative stress. Members of this family are involved in processes that protect the cell from the damaging effects of reactive oxygen species. They are related to globins, which are typically heme-containing proteins, suggesting that they may bind ...

[]

0

[ "PANTHER" ]

[ "PTHR47768" ]

[ "Oxidative_stress_globin-like" ]

[ 587 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Protostomia" ]

[ 587 ]

1

[ "Caenorhabditis elegans" ]

[ 6 ]

1

true

Family

Oxidative Stress Response Globin-like

Oxidative_stress_globin-like

2

IPR053342

53,342

Exosome cofactor and PTGS suppressor

Exosome_cofactor/PTGS_suppr

Family

611

true

false

This family of proteins includes cofactors of the cytoplasmic exosome, linking it to the SKI complex. Members of this family are involved in post-transcriptional gene silencing suppression, particularly by inhibiting the production of small interfering RNAs from specific loci related to cuticle membrane and wax product...

[]

0

[ "PANTHER" ]

[ "PTHR37260" ]

[ "Exosome_cofactor/PTGS_suppr" ]

[ 611 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Streptophyta" ]

[ 611 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 5, 3, 4 ]

3

true

Family

Exosome cofactor and PTGS suppressor

Exosome_cofactor/PTGS_suppr

8

IPR053343

53,343

Photosystem II mRNA-binding protein

PSII_mRNA-binding_protein

Family

589

true

false

This family of proteins is involved in the regulation of photosystem II (PSII) biogenesis and the formation of grana thylakoids in chloroplasts. Members of this family bind to the 5' UTR of PSII subunit mRNAs in a light-dependent manner, which is mediated by a redox-based mechanism. This interaction facilitates the ass...

[]

0

[ "PANTHER" ]

[ "PTHR47940" ]

[ "PSII_mRNA-binding_protein" ]

[ 589 ]

1

[]

0

[]

0

[]

0

[]

0

null

[ "Eukaryota" ]

[ 589 ]

1

[ "Arabidopsis thaliana", "Oryza sativa subsp. japonica", "Zea mays" ]

[ 9, 4, 4 ]

3

true

Family

Photosystem II mRNA-binding protein

PSII_mRNA-binding_protein

6