interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR057111 | 57,111 | Phage cement protein | Phage_cement | Family | 58 | false | false | This entry represents a small family of phage proteins. These proteins form a trimeric arrangement which stabilises the phage capsid. The proteins have what is known as a β-tulip fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23968"
] | [
"Phage_cement_3"
] | [
58
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati",
"Caudoviricetes"
] | [
4,
54
] | 2 | [] | [] | 0 | true | Family | Phage cement protein | Phage cement protein | Phage_cement | 9 |
IPR057112 | 57,112 | Phage g100-like protein | Phage_g100 | Family | 108 | false | false | This entry includes Yersinia phage phiR1-RT g100 protein which shows a partial β-barrel topology according to AlphaFold prediction. The function of members of this family is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23772"
] | [
"Phage_g100"
] | [
108
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses",
"marine sediment metagenome"
] | [
3,
103,
2
] | 3 | [] | [] | 0 | true | Family | Phage g100-like protein | Phage g100-like protein | Phage_g100 | 5 |
IPR057113 | 57,113 | Putative phage head-tail joining protein, N-terminal domain | Phage_H_T_join_N | Domain | 82 | false | false | This entry represents a domain found at the N-terminal end of a group of putative phage head to tail joining proteins. It is found associated with . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24214"
] | [
"Phage_H_T_join_2"
] | [
82
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Salmonella enterica I",
"Viruses"
] | [
6,
76
] | 2 | [] | [] | 0 | true | Domain | Putative phage head-tail joining protein, N-terminal domain | Putative phage head-tail joining protein, N-terminal domain | Phage_H_T_join_N | 4 |
IPR057114 | 57,114 | Putative phage head-tail joining protein, C-terminal domain | Phage_H_T_join_C | Domain | 78 | false | false | This entry represents the C-terminal domain found associated with phage head to tail connector domains , which suggests this domain is part of the phage structure. This region forms a large mainly α-helical domain. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24215"
] | [
"H_T_assoc"
] | [
78
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Salmonella enterica I",
"Viruses"
] | [
6,
72
] | 2 | [] | [] | 0 | true | Domain | Putative phage head-tail joining protein, C-terminal domain | Putative phage head-tail joining protein, C-terminal domain | Phage_H_T_join_C | 1 |
IPR057116 | 57,116 | Phage Pam3 gp32-like | Pam3_gp32 | Family | 77 | false | false | This entry represents a family of uncharacterised proteins from phages and bacterial prophages that includes the Pam3 phage gp32 protein ( ). Structure prediction shows that the protein is composed of a small globular domain. This protein forms a confident dimer according to structure prediction. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23992"
] | [
"Pam3_gp32"
] | [
77
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Marine Group I thaumarchaeote",
"Viruses",
"metagenomes"
] | [
4,
1,
36,
36
] | 4 | [] | [] | 0 | true | Family | Phage Pam3 gp32-like | Phage Pam3 gp32-like | Pam3_gp32 | 8 |
IPR057117 | 57,117 | Phage Pam3 gp59-like | Pam3_gp59 | Family | 7 | false | false | This entry represents a small family of phage proteins, including phage Pam3 gp59 ( ). The function of this protein is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23986"
] | [
"Pam3_gp59"
] | [
7
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Achromobacter phage Motura",
"Pseudomonadota"
] | [
1,
6
] | 2 | [] | [] | 0 | true | Family | Phage Pam3 gp59-like | Phage Pam3 gp59-like | Pam3_gp59 | 8 |
IPR057118 | 57,118 | Ring protein 1-like | R1-like | Family | 112 | false | false | This entry includes the Ring protein 1 (R1) from Bacteroides phage crAss001, also known as gp43, which is part of the tail assembly in CrAss-like phages (crassviruses). R1 forms one of five stacked dodecameric rings that make up the tail barrel. These proteins share a conserved fold consisting of two domains: an α-heli... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24228"
] | [
"CrAss_Ring_1"
] | [
112
] | 1 | [] | [] | [] | 0 | [
"7qog",
"7qoi",
"7qoj",
"7qol",
"8ckb"
] | 5 | [
"PUB00155591"
] | [
"37138077"
] | [
"Structural atlas of a human gut crassvirus."
] | [
2023
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses",
"marine sediment metagenome"
] | [
3,
101,
8
] | 3 | [] | [] | 0 | true | Family | Ring protein 1-like | Ring protein 1-like | R1-like | 5 |
IPR057120 | 57,120 | Phage tail tube protein 2 | Phage_TTP_2 | Family | 1,085 | false | false | This entry represents a family of phage proteins that by structural similarity are highly likely to be phage tail tube proteins that oligomerise to make the phage tail. These proteins are composed of a distinctive β-barrel structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23849"
] | [
"Phage_TTP_2"
] | [
1085
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Pseudomonadati",
"Viruses",
"metagenomes"
] | [
15,
6,
980,
84
] | 4 | [] | [] | 0 | true | Family | Phage tail tube protein 2 | Phage tail tube protein 2 | Phage_TTP_2 | 1 |
IPR057122 | 57,122 | Non-contractile tail sheath, TIM barrel | TIM-barrel_NCTSP | Domain | 588 | false | false | This entry represents the TIM-barrel domain found in the non-contractile tail sheath protein of Bacteriophage N4 (BPN4). This protein is essential for BPN4 infectivity and it is hypothesized that it mediates binding with target cell receptors [ ]. The function of this domain is unknown. This entry also includes sequenc... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23845"
] | [
"TIM-barrel_NCTSP"
] | [
588
] | 1 | [] | [] | [] | 0 | [
"9lc0"
] | 1 | [
"PUB00106835"
] | [
"18374942"
] | [
"Insight into DNA and protein transport in double-stranded DNA viruses: the structure of bacteriophage N4."
] | [
2008
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Diploscapter pachys",
"Methanobrevibacter thaueri",
"Viruses",
"ecological metagenomes"
] | [
453,
1,
1,
127,
6
] | 5 | [] | [] | 0 | true | Domain | Non-contractile tail sheath, TIM barrel | Non-contractile tail sheath, TIM barrel | TIM-barrel_NCTSP | 5 |
IPR057123 | 57,123 | STAND NTPase 4, small alpha/beta domain | STAND_NTPase4_dom | Domain | 304 | false | false | This entry represents a novel domain of the STAND-superfamily of AAA+ ATPases found in bacterial conflict systems [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24406"
] | [
"nSTAND_NTPase4"
] | [
304
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155486"
] | [
"37889040"
] | [
"Functionally comparable but evolutionarily distinct nucleotide-targeting effectors help identify conserved paradigms across diverse immune systems."
] | [
2023
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanoplanus limicola DSM 2279",
"metagenomes"
] | [
298,
1,
5
] | 3 | [] | [] | 0 | true | Domain | STAND NTPase 4, small alpha/beta domain | STAND NTPase 4, small alpha/beta domain | STAND_NTPase4_dom | 2 |
IPR057124 | 57,124 | Nuclear elongation and deformation protein 1-like, middle domain | Ned1-like_M | Domain | 1,233 | false | false | This domain is centrally located in Nuclear elongation and deformation protein 1 from Schizosaccharomyces pombe (Ned1) and similar fungal proteins. Ned1 may have a role in the maintenance of the nuclear envelope structure and in minichromosome stability [ ]. This domain is also found in Phosphatidic acid phosphohydrola... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24565"
] | [
"Ned1_M"
] | [
1233
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-SCE-1483191",
"R-SCE-1483213",
"R-SCE-4419969",
"R-SCE-75109",
"R-SPO-1483191",
"R-SPO-1483213",
"R-SPO-4419969",
"R-SPO-75109"
] | [
"REACTOME:R-SCE-1483191",
"REACTOME:R-SCE-1483213",
"REACTOME:R-SCE-4419969",
"REACTOME:R-SCE-75109",
"REACTOME:R-SPO-1483191",
"REACTOME:R-SPO-1483213",
"REACTOME:R-SPO-4419969",
"REACTOME:R-SPO-75109"
] | 8 | [] | 0 | [
"PUB00017102",
"PUB00017108",
"PUB00045014",
"PUB00059933"
] | [
"8437575",
"12376568",
"16467296",
"16968695"
] | [
"A gene, SMP2, involved in plasmid maintenance and respiration in Saccharomyces cerevisiae encodes a highly charged protein.",
"An evolutionarily conserved fission yeast protein, Ned1, implicated in normal nuclear morphology and chromosome stability, interacts with Dis3, Pim1/RCC1 and an essential nucleoporin.",
... | [
1993,
2002,
2006,
2006
] | 4 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1233
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1,
1
] | 3 | true | Domain | Nuclear elongation and deformation protein 1-like, middle domain | Nuclear elongation and deformation protein 1-like, middle domain | Ned1-like_M | 5 |
IPR057126 | 57,126 | Neuron navigator 1-like, ubiquitin-like domain | NAV1-like_ubiquitin-like | Domain | 7,459 | false | false | This domain is found in human Neuron navigator 1 (NAV1) and similar sequences from animals. NAV1 may be involved in neuronal migration. It is predicted to adopt a ubiquitin-like fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23092"
] | [
"Ubiquitin_6"
] | [
7459
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eumetazoa"
] | [
7459
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
143,
7,
11,
9,
23
] | 6 | true | Domain | Neuron navigator 1-like, ubiquitin-like domain | Neuron navigator 1-like, ubiquitin-like domain | NAV1-like_ubiquitin-like | 9 |
IPR057127 | 57,127 | MEX67-like, NTF2-like domain | NTF2_MEX67 | Domain | 75 | false | false | This entry represents a NTF2-like domain [ ] of approximately 220 residues long found in a set of uncharacterised kinetoplasts proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23056"
] | [
"NTF2_MEX67"
] | [
75
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155762"
] | [
"22123199"
] | [
"The structure of the NXF2/NXT1 heterodimeric complex reveals the combined specificity and versatility of the NTF2-like fold."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Metakinetoplastina"
] | [
75
] | 1 | [] | [] | 0 | true | Domain | MEX67-like, NTF2-like domain | MEX67-like, NTF2-like domain | NTF2_MEX67 | 2 |
IPR057128 | 57,128 | MgtT | MgtT | Family | 10 | false | false | This protein family includes the uncharacterised protein MgtT from Escherichia coli, a 34-residues micropeptide encoded by a small open reading frame (smORF) that lies just downstream of mgtS and is encoded antisense of the mgrR small regulatory RNA gene. Proteins 50 or fewer residues-long have been shown to regulate t... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23498"
] | [
"MgtT"
] | [
10
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00105763"
] | [
"30837344"
] | [
"Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes."
] | [
2019
] | 1 | [] | [] | 0 | 0 | null | [
"Enterobacteriaceae"
] | [
10
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | MgtT | MgtT | MgtT | 5 |
IPR057129 | 57,129 | Micropeptide inhibiting actin cytoskeleton | MIAC | Family | 29 | false | false | This protein family includes human Micropeptide inhibiting actin cytoskeleton (MIAC) and similar sequences from vertebrates. MIAC is a 51-residues long protein that reduces filamentous actin fibres by interacting with aquaporin AQP2. It also inhibits the activation of the EREG/EGFR signalling pathway. Low expression of... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23701"
] | [
"MIAC"
] | [
29
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155741",
"PUB00155742"
] | [
"36117171",
"32176498"
] | [
"Micropeptide MIAC inhibits the tumor progression by interacting with AQP2 and inhibiting EREG/EGFR signaling in renal cell carcinoma.",
"Micropeptide MIAC Inhibits HNSCC Progression by Interacting with Aquaporin 2."
] | [
2022,
2020
] | 2 | [] | [] | 0 | 0 | null | [
"Euteleostomi"
] | [
29
] | 1 | [
"Homo sapiens",
"Rattus norvegicus"
] | [
1,
3
] | 2 | true | Family | Micropeptide inhibiting actin cytoskeleton | Micropeptide inhibiting actin cytoskeleton | MIAC | 7 |
IPR057130 | 57,130 | Myosin VII, N-terminal domain | Myosin_VII_N | Domain | 3,224 | false | false | This entry represents a small 5-stranded β-barrel domain found at the N-terminal end of some animal myosin VII proteins. Myosin-VII proteins are actin-based motor molecules with ATPase activity, playing crucial roles in intracellular movements and cellular projections. They function as single-molecule cargo transporter... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24123"
] | [
"Myosin_VII_N"
] | [
3224
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-2453902",
"R-DME-2453902",
"R-HSA-2453902",
"R-HSA-9662360",
"R-HSA-9662361",
"R-MMU-2453902"
] | [
"REACTOME:R-CEL-2453902",
"REACTOME:R-DME-2453902",
"REACTOME:R-HSA-2453902",
"REACTOME:R-HSA-9662360",
"REACTOME:R-HSA-9662361",
"REACTOME:R-MMU-2453902"
] | 6 | [
"9dfs",
"9dfv"
] | 2 | [
"PUB00072034",
"PUB00087364",
"PUB00127807",
"PUB00127810",
"PUB00127812",
"PUB00160407"
] | [
"24725409",
"26812018",
"21493626",
"16585515",
"15579689",
"32209652"
] | [
"Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion.",
"ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation.",
"The Usher 1B protein, MYO7A, is required for normal localization and function of the visual retinoid cycle enzyme, RPE65.",
"Dimerized Drosophil... | [
2014,
2016,
2011,
2006,
2004,
2020
] | 6 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
3224
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
18,
9,
4,
7,
9
] | 6 | true | Domain | Myosin VII, N-terminal domain | Myosin VII, N-terminal domain | Myosin_VII_N | 8 |
IPR057131 | 57,131 | Fibronectin type-III domain, nematodes | Fn3_nem | Domain | 144 | false | false | This entry represents a fibronectin type-III domain found primarily in nematode proteins. The proteins contain several conserved cysteine residues that may either form disulphide bridges or possibly a zinc binding site. Many members of this family also contain a predicted transmembrane region following the FN3 domains,... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24221"
] | [
"Fn3_nematode"
] | [
144
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Nematoda"
] | [
144
] | 1 | [
"Caenorhabditis elegans"
] | [
2
] | 1 | true | Domain | Fibronectin type-III domain, nematodes | Fibronectin type-III domain, nematodes | Fn3_nem | 9 |
IPR057132 | 57,132 | Nuclear anchorage protein 1, spectrin repeat domain | ANC1_spectrin_dom | Domain | 121 | false | false | This entry represents a region of spectrin repeats found in Nuclear anchorage protein 1 from Caenorhabditis elegans and similar proteins from worms. Nuclear anchorage protein 1 (ANC-1) is a key protein in Caenorhabditis elegans that plays a central role in nuclear and mitochondrial anchoring [ , , , ]. ANC-1 has a role... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24531"
] | [
"ANC1_spectrin"
] | [
121
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00016670",
"PUB00090287",
"PUB00146850",
"PUB00155494",
"PUB00160082"
] | [
"12169658",
"22298703",
"10375507",
"15773756",
"6889924"
] | [
"Role of ANC-1 in tethering nuclei to the actin cytoskeleton.",
"Neural maintenance roles for the matrix receptor dystroglycan and the nuclear anchorage complex in Caenorhabditis elegans.",
"UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans developmen... | [
2002,
2012,
1999,
2005,
1982
] | 5 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
121
] | 1 | [
"Caenorhabditis elegans"
] | [
3
] | 1 | true | Domain | Nuclear anchorage protein 1, spectrin repeat domain | Nuclear anchorage protein 1, spectrin repeat domain | ANC1_spectrin_dom | 8 |
IPR057133 | 57,133 | Nuclear anchorage protein 1, spectrin repeat domain 2 | Spectrin_Anc-1_2 | Domain | 166 | false | false | This entry represents spectrin-like repeats found in Nuclear anchorage protein 1 from Caenorhabditis elegans and similar proteins from worms. Nuclear anchorage protein 1 (ANC-1) is a key protein in Caenorhabditis elegans that plays a central role in nuclear and mitochondrial anchoring [ , , , ]. ANC-1 has a role in pos... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24615"
] | [
"Spectrin_Anc-1_2"
] | [
166
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00016670",
"PUB00090287",
"PUB00146850",
"PUB00155494",
"PUB00160082"
] | [
"12169658",
"22298703",
"10375507",
"15773756",
"6889924"
] | [
"Role of ANC-1 in tethering nuclei to the actin cytoskeleton.",
"Neural maintenance roles for the matrix receptor dystroglycan and the nuclear anchorage complex in Caenorhabditis elegans.",
"UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans developmen... | [
2002,
2012,
1999,
2005,
1982
] | 5 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
166
] | 1 | [
"Caenorhabditis elegans"
] | [
3
] | 1 | true | Domain | Nuclear anchorage protein 1, spectrin repeat domain 2 | Nuclear anchorage protein 1, spectrin repeat domain 2 | Spectrin_Anc-1_2 | 4 |
IPR057134 | 57,134 | Nuclear anchorage protein 1, spectrin-like repeat domain 3 | Spectrin_Anc-1_3 | Domain | 239 | false | false | This entry represents spectrin-like repeats found in Nuclear anchorage protein 1 from Caenorhabditis elegans and similar proteins from worms. Nuclear anchorage protein 1 (ANC-1) is a key protein in Caenorhabditis elegans that plays a central role in nuclear and mitochondrial anchoring [ , , , ]. ANC-1 has a role in pos... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24611"
] | [
"Spectrin_Anc-1"
] | [
239
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00016670",
"PUB00090287",
"PUB00146850",
"PUB00155494",
"PUB00160082"
] | [
"12169658",
"22298703",
"10375507",
"15773756",
"6889924"
] | [
"Role of ANC-1 in tethering nuclei to the actin cytoskeleton.",
"Neural maintenance roles for the matrix receptor dystroglycan and the nuclear anchorage complex in Caenorhabditis elegans.",
"UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans developmen... | [
2002,
2012,
1999,
2005,
1982
] | 5 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
239
] | 1 | [
"Caenorhabditis elegans"
] | [
3
] | 1 | true | Domain | Nuclear anchorage protein 1, spectrin-like repeat domain 3 | Nuclear anchorage protein 1, spectrin-like repeat domain 3 | Spectrin_Anc-1_3 | 6 |
IPR057135 | 57,135 | Disease resistance protein At4g27190-like, leucine-rich repeats | At4g27190-like_LRR | Domain | 22,319 | false | false | This entry represents a region of leucine-rich repeats found in Disease resistance protein At4g27190 from Arabidopsis thaliana and similar proteins predominantly from plants. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23247"
] | [
"LRR_RPS2"
] | [
22319
] | 1 | [] | [] | [] | 0 | [
"9h2l",
"9h4i",
"9h73"
] | 3 | [
"PUB00155720",
"PUB00155721"
] | [
"12581527",
"8091210"
] | [
"Arabidopsis RIN4 is a target of the type III virulence effector AvrRpt2 and modulates RPS2-mediated resistance.",
"RPS2 of Arabidopsis thaliana: a leucine-rich repeat class of plant disease resistance genes."
] | [
2003,
1994
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Mimivirus LCMiAC01"
] | [
5,
22313,
1
] | 3 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
43,
62,
24
] | 3 | true | Domain | Disease resistance protein At4g27190-like, leucine-rich repeats | Disease resistance protein At4g27190-like, leucine-rich repeats | At4g27190-like_LRR | 5 |
IPR057136 | 57,136 | At2g35280-like, TPR domain | At2g35280_TPR_dom | Domain | 4,206 | false | false | This entry represents the predicted tetratrico peptide repeat (TPR) domain found in F-box proteins At2g35280, At5g50450 and At1g67340 from Arabidopsis thaliana and similar plant proteins. This entry is found associated with in some members of this family. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23310"
] | [
"TPR_27"
] | [
4206
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"hydrothermal vent metagenome"
] | [
21,
4184,
1
] | 3 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
29,
19,
20
] | 3 | true | Domain | At2g35280-like, TPR domain | At2g35280-like, TPR domain | At2g35280_TPR_dom | 4 |
IPR057138 | 57,138 | Platelet endothelial aggregation receptor 1-like, EGF domain | EGF_PEAR1L-like | Domain | 12,044 | false | false | This domain is found in human Platelet endothelial aggregation receptor 1 (PEAR1L) and related proteins such as Multiple epidermal growth factor-like domains protein 10 and 11 (MEGF10 and MEGF11). Platelet Endothelial Aggregation Receptor 1 (PEAR1) is a type I transmembrane protein that plays a significant role in both... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23301"
] | [
"EGF_PEAR1L"
] | [
12044
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-3000484",
"R-HSA-9830364",
"R-HSA-9830674"
] | [
"REACTOME:R-HSA-3000484",
"REACTOME:R-HSA-9830364",
"REACTOME:R-HSA-9830674"
] | 3 | [
"2m74",
"2ygq",
"5ms9",
"8hn0",
"8hna"
] | 5 | [
"PUB00059810",
"PUB00160087",
"PUB00160088",
"PUB00160089"
] | [
"21743455",
"36792666",
"26156496",
"18511696"
] | [
"Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1.",
"SVEP1 is an endogenous ligand for the orphan receptor PEAR1.",
"Platelet endothelial aggregation receptor-1: a novel modifier of neoangiogenesis.",
"A novel variant in the platelet endothelial aggregation receptor-1 gene is associat... | [
2011,
2023,
2015,
2008
] | 4 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
12044
] | 1 | [
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
32,
44,
31,
22,
40
] | 6 | true | Domain | Platelet endothelial aggregation receptor 1-like, EGF domain | Platelet endothelial aggregation receptor 1-like, EGF domain | EGF_PEAR1L-like | 4 |
IPR057143 | 57,143 | P-granule-associated protein DEPS-1, second OB-fold | OB_DEPS-1_2nd | Domain | 161 | false | false | This domain is found in the P-granule-associated protein DEPS-1 from C. elegans and related proteins. DEPS-1 is predicted to contain six OB-fold-like β-barrel domains. This entry represents the second of these domains. DEPS-1 is a component of the P-granules and is required for their formation and integrity in adult ge... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24342"
] | [
"OB_DEPS-1_2nd"
] | [
161
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155770",
"PUB00155771"
] | [
"18234720",
"32843637"
] | [
"DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells.",
"DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans."
] | [
2008,
2020
] | 2 | [] | [] | 0 | 0 | null | [
"Rhabditida"
] | [
161
] | 1 | [
"Caenorhabditis elegans"
] | [
4
] | 1 | true | Domain | P-granule-associated protein DEPS-1, second OB-fold | P-granule-associated protein DEPS-1, second OB-fold | OB_DEPS-1_2nd | 3 |
IPR057144 | 57,144 | P-granule-associated protein DEPS-1, sixth OB-fold | OB_DEPS-1_6th | Domain | 90 | false | false | This domain is found in the P-granule-associated protein DEPS-1 from C.elegans and related proteins. DEPS-1 is predicted to contain six OB-fold-like β-barrel domains. This entry represents the sixth of these domains. DEPS-1 is a component of the P-granules and is required for their formation and integrity in adult germ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24341"
] | [
"OB_DEPS-1_6th"
] | [
90
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155770",
"PUB00155771"
] | [
"18234720",
"32843637"
] | [
"DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells.",
"DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans."
] | [
2008,
2020
] | 2 | [] | [] | 0 | 0 | null | [
"Rhabditida"
] | [
90
] | 1 | [
"Caenorhabditis elegans"
] | [
1
] | 1 | true | Domain | P-granule-associated protein DEPS-1, sixth OB-fold | P-granule-associated protein DEPS-1, sixth OB-fold | OB_DEPS-1_6th | 9 |
IPR057145 | 57,145 | P116 | P116 | Family | 28 | false | false | The structure of P116 (MPN213 or MG075), solved by cryo-electron microscopy, reveals a novel protein fold consisting of a homodimeric core region with a large hydrophobic cavity that binds and extracts lipids. Each monomer also contains an N-terminal domain. Conformational changes between the lipid-bound and lipid-free... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF23707"
] | [
"P116"
] | [
28
] | 1 | [] | [] | [] | 0 | [
"8a9a",
"8a9b",
"9fch"
] | 3 | [
"PUB00154800"
] | [
"36782049"
] | [
"Essential protein P116 extracts cholesterol and other indispensable lipids for Mycoplasmas."
] | [
2023
] | 1 | [
"IPR054689"
] | [] | 1 | 0 | 1 | [
"Mycoplasmatota"
] | [
28
] | 1 | [] | [] | 0 | true | Family | P116 | P116 | P116 | 5 |
IPR057147 | 57,147 | P-granule-associated protein DEPS-1, third OB-fold domain | OB_DEPS-1_3rd | Domain | 101 | false | false | This domain is found in the P-granule-associated protein DEPS-1 from Caenorhabditis elegans and related proteins from worms. DEPS-1 is predicted to contain six OB-fold-like β-barrel domains. This entry represents the third of these domains. DEPS-1 is a component of the P-granules and is required for their formation and... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF24339"
] | [
"OB_DEPS-1_3rd"
] | [
101
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00155770",
"PUB00155771"
] | [
"18234720",
"32843637"
] | [
"DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells.",
"DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans."
] | [
2008,
2020
] | 2 | [] | [] | 0 | 0 | null | [
"Rhabditida"
] | [
101
] | 1 | [
"Caenorhabditis elegans"
] | [
1
] | 1 | true | Domain | P-granule-associated protein DEPS-1, third OB-fold domain | P-granule-associated protein DEPS-1, third OB-fold domain | OB_DEPS-1_3rd | 2 |
IPR057148 | 57,148 | Repeat of unknown function DUF7826 | DUF7826 | Repeat | 42 | false | false | This entry represents a family of small uncharacterised bacterial α solenoid proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25159"
] | [
"DUF7826"
] | [
42
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Thermodesulfobacteriota",
"hydrothermal vent metagenome"
] | [
40,
2
] | 2 | [] | [] | 0 | true | Repeat | Repeat of unknown function DUF7826 | Repeat of unknown function DUF7826 | DUF7826 | 8 |
IPR057149 | 57,149 | Domain of unknown function DUF7827 | DUF7827 | Domain | 596 | false | false | This domain of unknown function is found in a group of uncharacterised archaeal proteins. It is predicted to adopt an all-beta structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25162"
] | [
"DUF7827"
] | [
596
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
596
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7827 | Domain of unknown function DUF7827 | DUF7827 | 8 |
IPR057150 | 57,150 | Domain of unknown function DUF7828 | DUF7828 | Domain | 860 | false | false | This domain is found in uncharacterised bacterial proteins. It contains highly conserved cysteine and histidine residues that are likely involved in zinc coordination. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25165"
] | [
"DUF7828"
] | [
860
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"human gut metagenome"
] | [
859,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7828 | Domain of unknown function DUF7828 | DUF7828 | 1 |
IPR057151 | 57,151 | Domain of unknown function DUF7829 | DUF7829 | Domain | 124 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an alpha- helical structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25167"
] | [
"DUF7829"
] | [
124
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati"
] | [
124
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7829 | Domain of unknown function DUF7829 | DUF7829 | 2 |
IPR057152 | 57,152 | Domain of unknown function DUF7830 | DUF7830 | Domain | 236 | false | false | This domain is found in uncharacterised bacterial proteins. It has three highly conserved cysteine residues and a histidine that may be involved in zinc coordination. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25169"
] | [
"DUF7830"
] | [
236
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Palaeococcus pacificus DY20341",
"Rhabditida",
"unclassified sequences"
] | [
231,
1,
2,
2
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7830 | Domain of unknown function DUF7830 | DUF7830 | 9 |
IPR057153 | 57,153 | Domain of unknown function DUF7831 | DUF7831 | Domain | 148 | false | false | This entry represents a family of uncharacterised proteins which form a compact domain. Structure prediction of suggests a highly confident homodimer (iPTM=0.93). This protein is found in a mixture of bacteria and phage. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25176"
] | [
"DUF7831"
] | [
148
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadati",
"Viruses",
"metagenomes"
] | [
5,
60,
66,
17
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7831 | Domain of unknown function DUF7831 | DUF7831 | 4 |
IPR057154 | 57,154 | Domain of unknown function DUF7832 | DUF7832 | Domain | 1,029 | false | false | This entry represents an uncharacterised bacterial protein domain. This domain is found in single domain proteins as well as in large multidomain proteins that contain immunity related domains. This suggests that this family may play a role in a toxin/antitoxin system. The domain contains two structural sites that cont... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25191"
] | [
"DUF7832"
] | [
1029
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
1019,
7,
3
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7832 | Domain of unknown function DUF7832 | DUF7832 | 2 |
IPR057155 | 57,155 | Domain of unknown function DUF7833 | DUF7833 | Domain | 444 | false | false | This entry represents a small family of protein domains related to . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25200"
] | [
"DUF7833"
] | [
444
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteroidota",
"Popillia japonica",
"Viruses",
"metagenomes"
] | [
428,
1,
11,
4
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7833 | Domain of unknown function DUF7833 | DUF7833 | 6 |
IPR057156 | 57,156 | Domain of unknown function DUF7834 | DUF7834 | Domain | 890 | false | false | This entry represents an uncharacterised domain found at the C terminus of proteins that contain a domain at the N terminus. This domain is composed of multiple α-helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25202"
] | [
"DUF7834"
] | [
890
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
882,
8
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7834 | Domain of unknown function DUF7834 | DUF7834 | 8 |
IPR057157 | 57,157 | Domain of unknown function DUF7835 | DUF7835 | Domain | 361 | false | false | This entry represents a small family of uncharacterised proteins found in Halobacteria. They contain two pairs of conserved cysteines that are likely involved in metal coordination. These proteins are predicted to structurally resemble Zinc beta-ribbon domains. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25205"
] | [
"DUF7835"
] | [
361
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
361
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7835 | Domain of unknown function DUF7835 | DUF7835 | 7 |
IPR057158 | 57,158 | Domain of unknown function DUF7836 | DUF7836 | Domain | 361 | false | false | This entry represents a small family of uncharacterised proteins found in Halobacteria. They contain two pairs of conserved cysteines that are likely involved in metal coordination. These proteins are predicted to structurally resemble Zinc beta-ribbon domains. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25206"
] | [
"DUF7836"
] | [
361
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota",
"Halobacteriales",
"Opisthokonta",
"viral metagenome"
] | [
5,
353,
2,
1
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7836 | Domain of unknown function DUF7836 | DUF7836 | 3 |
IPR057159 | 57,159 | Domain of unknown function DUF7837 | DUF7837 | Domain | 186 | false | false | This entry represents a small family of uncharacterised proteins found in Halobacteria. They contain two pairs of conserved cysteines that are likely involved in metal coordination. These proteins are predicted to structurally resemble Zinc beta-ribbon domains. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25207"
] | [
"DUF7837"
] | [
186
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales",
"Passeriformes"
] | [
184,
2
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7837 | Domain of unknown function DUF7837 | DUF7837 | 5 |
IPR057160 | 57,160 | Domain of unknown function DUF7838 | DUF7838 | Domain | 272 | false | false | This entry represents a small family of uncharacterised proteins found in Halobacteria. They contain two pairs of conserved cysteines that are likely involved in metal coordination. These proteins are predicted to structurally resemble Zinc beta-ribbon domains. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25208"
] | [
"DUF7838"
] | [
272
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales",
"Opisthokonta",
"marine sediment metagenome"
] | [
267,
4,
1
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7838 | Domain of unknown function DUF7838 | DUF7838 | 6 |
IPR057161 | 57,161 | Domain of unknown function DUF7839 | DUF7839 | Domain | 631 | false | false | This domain is found at the C-terminal end of a group of uncharacterised archaeal proteins. This domain is predicted to adopt an α-helical structure. Members of this family have an HTH domain at the N terminus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25211"
] | [
"DUF7839"
] | [
631
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanobacteriati",
"unclassified sequences"
] | [
14,
603,
14
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7839 | Domain of unknown function DUF7839 | DUF7839 | 6 |
IPR057162 | 57,162 | Domain of unknown function DUF7840 | DUF7840 | Domain | 2,009 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold onto a meander β-barrel and it is likely associated with the membrane. It is frequently found in combination with . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25222"
] | [
"DUF7840"
] | [
2009
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Potamilus streckersoni",
"metagenomes"
] | [
1969,
1,
39
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7840 | Domain of unknown function DUF7840 | DUF7840 | 9 |
IPR057163 | 57,163 | Domain of unknown function DUF7841 | DUF7841 | Domain | 230 | false | false | This entry represents an uncharacterised bacteriophage family of proteins. Structure prediction with suggests that members of this family will form homodimeric complexes (iPTM=0.87 and pTM=0.89). | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25223"
] | [
"DUF7841"
] | [
230
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Cylicocyclus nassatus",
"Viruses",
"human gut metagenome"
] | [
86,
1,
139,
4
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7841 | Domain of unknown function DUF7841 | DUF7841 | 8 |
IPR057164 | 57,164 | Domain of unknown function DUF7842 | DUF7842 | Domain | 356 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold onto an α-helical bundle consisting of five α-helices. It is frequently found in combination with and . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25224"
] | [
"DUF7842"
] | [
356
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"ecological metagenomes"
] | [
352,
4
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7842 | Domain of unknown function DUF7842 | DUF7842 | 5 |
IPR057165 | 57,165 | Domain of unknown function DUF7843 | DUF7843 | Domain | 1,964 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to fold into an α-helical array. It is frequently found in combination with and . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25225"
] | [
"DUF7843"
] | [
1964
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Potamilus streckersoni",
"ecological metagenomes"
] | [
1926,
1,
37
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7843 | Domain of unknown function DUF7843 | DUF7843 | 4 |
IPR057167 | 57,167 | Domain of unknown function DUF7845 | DUF7845 | Domain | 378 | false | false | This entry represents a domain of unknown function. In some proteins the is a C-terminal HTH domain that presumably binds to DNA. This domain may bind to an as unyet identified ligand to enable regulation of bacterial genes. This domain contains a large β sheet composed of 11 β strands with helices packed on the convex... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25227"
] | [
"DUF7845"
] | [
378
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Betapleolipovirus",
"viral metagenome"
] | [
368,
9,
1
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7845 | Domain of unknown function DUF7845 | DUF7845 | 3 |
IPR057168 | 57,168 | Domain of unknown function DUF7846 | DUF7846 | Domain | 298 | false | false | This is a domain of unknown function, mainly found in a group of archaeal sequences such as HVO_1708 ( ). This domain may have a fold related to glycosyltransferases. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25230"
] | [
"DUF7846"
] | [
298
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Halobacteria",
"freshwater metagenome"
] | [
21,
273,
4
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7846 | Domain of unknown function DUF7846 | DUF7846 | 4 |
IPR057169 | 57,169 | Domain of unknown function DUF7847 | DUF7847 | Domain | 3,644 | false | false | This is a domain of unknown function found in a group of archaeal and bacterial sequences, including HVO_0229 ( ). This domain may consist of several transmembrane helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25231"
] | [
"DUF7847"
] | [
3644
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
851,
2758,
11,
24
] | 4 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7847 | Domain of unknown function DUF7847 | DUF7847 | 8 |
IPR057170 | 57,170 | Domain of unknown function DUF7848 | DUF7848 | Domain | 961 | false | false | This entry represents a likely zinc binding domain that according to structural modelling may form homodimers. The domain is primarily found in actinobacteria as well as a small range of bacteriophage. The function of this domain is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25232"
] | [
"DUF7848"
] | [
961
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Actinomycetes",
"Caudoviricetes"
] | [
941,
20
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7848 | Domain of unknown function DUF7848 | DUF7848 | 9 |
IPR057171 | 57,171 | Domain of unknown function DUF7849 | DUF7849 | Domain | 306 | false | false | This domain is found in uncharacterised proteins from Gram-negative bacteria. It has a detectable similarity to OmpA-like transmembrane domains and it is predicted to adopt a similar β-barrel structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25233"
] | [
"DUF7849"
] | [
306
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteroidota",
"hydrothermal vent metagenome"
] | [
305,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7849 | Domain of unknown function DUF7849 | DUF7849 | 8 |
IPR057172 | 57,172 | Domain of unknown function DUF7850 | DUF7850 | Domain | 76 | false | false | This domain is found in uncharacterised proteins mainly from Actinomycetes. It is predicted to adopt a β-sandwich structure with significant similarity to carbohydrate-binding modules in particular to CBM_4_9 ( ). | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25235"
] | [
"DUF7850"
] | [
76
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
76
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7850 | Domain of unknown function DUF7850 | DUF7850 | 9 |
IPR057173 | 57,173 | Domain of unknown function DUF7851 | DUF7851 | Domain | 700 | false | false | This domain is found in uncharacterised proteins from plants. It is predicted to adopt a structure consisting of a mixed β-sheet and α-helices packed on both sides with unique topology. It contains a highly conserved sequence motif RxKxRKG that contributes to the formation of a highly basic surface patch. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF25236",
"PTHR36375"
] | [
"DUF7851",
""
] | [
699,
684
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
700
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
5,
5
] | 3 | true | Domain | Domain of unknown function DUF7851 | Domain of unknown function DUF7851 | DUF7851 | 1 |
IPR057174 | 57,174 | Domain of unknown function DUF7852 | DUF7852 | Domain | 1,018 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to adopt a β-sandwich structure with long twisted strands. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25250"
] | [
"DUF7852"
] | [
1018
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota",
"bioreactor metagenome"
] | [
1016,
2
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7852 | Domain of unknown function DUF7852 | DUF7852 | 9 |
IPR057175 | 57,175 | Protein of unknown function DUF7853 | DUF7853 | Family | 215 | false | false | This family represents a group of uncharacterised proteins from halobacteria. Members are around 100 residues and are predicted to adopt a mainly alpha-configuration. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25251"
] | [
"DUF7853"
] | [
215
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
215
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7853 | Protein of unknown function DUF7853 | DUF7853 | 6 |
IPR057176 | 57,176 | Protein of unknown function DUF7854 | DUF7854 | Family | 199 | false | false | This family represents a group of uncharacterised proteins from halobacteria. Members are around 100 residues and are predicted to adopt an α-β configuration. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25252"
] | [
"DUF7854"
] | [
199
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
199
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7854 | Protein of unknown function DUF7854 | DUF7854 | 9 |
IPR057177 | 57,177 | DUF7855, N-terminal dimerisation domain | DUF7855_N | Domain | 213 | false | false | This entry represents the N-terminal domain found in DUF7855 family proteins from halobacteria. This domain is predicted to mediate dimerisation as well as DNA-binding. This domain belongs to the dimeric α/β barrel superfamily. There is a notable pocket in each subunit beneath the DNA-binding interface that might might... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25253"
] | [
"DUF7855"
] | [
213
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
213
] | 1 | [] | [] | 0 | true | Domain | DUF7855, N-terminal dimerisation domain | DUF7855, N-terminal dimerisation domain | DUF7855_N | 4 |
IPR057178 | 57,178 | Protein of unknown function DUF7856 | DUF7856 | Family | 214 | false | false | This family represents a group of uncharacterised proteins from halobacteria. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25254"
] | [
"DUF7856"
] | [
214
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
214
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7856 | Protein of unknown function DUF7856 | DUF7856 | 6 |
IPR057179 | 57,179 | Protein of unknown function DUF7857 | DUF7857 | Family | 261 | false | false | This family represents a group of uncharacterised proteins from halobacteria. Members are around 284 residues and are predicted to adopt a mainly β configuration an the N-terminal and show short α-helices in the C-terminal. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25256"
] | [
"DUF7857"
] | [
261
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
261
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7857 | Protein of unknown function DUF7857 | DUF7857 | 1 |
IPR057180 | 57,180 | Protein of unknown function DUF7858 | DUF7858 | Family | 201 | false | false | This family represents a group of uncharacterised proteins from halobacteria. Members are predicted to adopt a mainly alpha configuration. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25257"
] | [
"DUF7858"
] | [
201
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
201
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7858 | Protein of unknown function DUF7858 | DUF7858 | 7 |
IPR057181 | 57,181 | Protein of unknown function DUF7859 | DUF7859 | Family | 225 | false | false | This family represents a group of very short uncharacterised sequences from halobacteria. Members are predicted to adopt an α-helical configuration. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25258"
] | [
"DUF7859"
] | [
225
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
225
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7859 | Protein of unknown function DUF7859 | DUF7859 | 6 |
IPR057182 | 57,182 | Protein of unknown function DUF7860 | DUF7860 | Family | 242 | false | false | This family represents a group of short uncharacterised proteins from halobacteria. Members are predicted to adopt an alpha configuration. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25259"
] | [
"DUF7860"
] | [
242
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteria"
] | [
242
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7860 | Protein of unknown function DUF7860 | DUF7860 | 5 |
IPR057183 | 57,183 | Protein of unknown function DUF7861 | DUF7861 | Family | 152 | false | false | This family represents a group of uncharacterised proteins from halobacteria. Members are around 100 residues and are predicted to adopt a mainly beta configuration. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25260"
] | [
"DUF7861"
] | [
152
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Halobacteriales"
] | [
152
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7861 | Protein of unknown function DUF7861 | DUF7861 | 6 |
IPR057184 | 57,184 | Domain of unknown function DUF7862 | DUF7862 | Domain | 49 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to adopt a β-sandwich with Ig-like topology. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25262"
] | [
"DUF7862"
] | [
49
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanomicrobia",
"bioreactor metagenome"
] | [
43,
2,
4
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7862 | Domain of unknown function DUF7862 | DUF7862 | 7 |
IPR057188 | 57,188 | Domain of unknown function DUF7866 | DUF7866 | Domain | 1,105 | false | false | This domain is found in uncharacterised proteins from plants. It is predicted to fold into a three-stranded antiparallel twisted β-sheet. It contains several highly conserved cysteine residues that are predicted to form disulfide bonds. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25268"
] | [
"DUF7866"
] | [
1105
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
1105
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
5,
9,
17
] | 3 | true | Domain | Domain of unknown function DUF7866 | Domain of unknown function DUF7866 | DUF7866 | 8 |
IPR057189 | 57,189 | Domain of unknown function DUF7867 | DUF7867 | Domain | 126 | false | false | This domain is found in a group of uncharacterised proteins from alphaproteobacteria. This domain is usually found associated with and is predicted to form a three -sided beta-helix. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25269"
] | [
"DUF7867"
] | [
126
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Rhodobacterales",
"marine sediment metagenome"
] | [
125,
1
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7867 | Domain of unknown function DUF7867 | DUF7867 | 4 |
IPR057190 | 57,190 | Domain of unknown function DUF7868 | DUF7868 | Domain | 398 | false | false | This domain is found in uncharacterised bacterial proteins. It has similarity to the C-terminal domain of Haemocyanin and it is predicted to adopt similar β-sandwich fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25271"
] | [
"DUF7868"
] | [
398
] | 1 | [] | [] | [] | 0 | [
"8b74"
] | 1 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
398
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7868 | Domain of unknown function DUF7868 | DUF7868 | 7 |
IPR057191 | 57,191 | Domain of unknown function DUF7869 | DUF7869 | Domain | 5,470 | false | false | This domain is found in uncharacterised eukaryotic proteins. It is predicted to adopt a globular structure composed of a curved β-sheet and helices packed on it. It contains conserved histidine and aspartate residues some of which cluster in space. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25273"
] | [
"DUF7869"
] | [
5470
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Pseudomonadati",
"metagenomes"
] | [
5458,
9,
3
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7869 | Domain of unknown function DUF7869 | DUF7869 | 7 |
IPR057192 | 57,192 | Domain of unknown function DUF7870 | DUF7870 | Domain | 2,526 | false | false | This domain is found in uncharacterised plant proteins. It has detectable similarity to methyltransferases and it is predicted to adopt similar structure. It contains two highly conserved cysteines and a histidine. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25276"
] | [
"DUF7870"
] | [
2526
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
2526
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
18,
6,
4
] | 3 | true | Domain | Domain of unknown function DUF7870 | Domain of unknown function DUF7870 | DUF7870 | 4 |
IPR057193 | 57,193 | Domain of unknown function DUF7871 | DUF7871 | Domain | 892 | false | false | This domain is found in uncharacterised fungal proteins. It contains a number of highly conserved cysteine residues some of which may be involved in metal coordination. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25277"
] | [
"DUF7871"
] | [
892
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
892
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF7871 | Domain of unknown function DUF7871 | DUF7871 | 3 |
IPR057194 | 57,194 | Domain of unknown function DUF7872 | DUF7872 | Domain | 923 | false | false | This domain is found in uncharacterised fungal proteins. It contains highly conserved cysteine residues that are predicted to form disulfide bonds. This domain is predicted to fold into an α/β structure with an unique topology. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25278"
] | [
"DUF7872"
] | [
923
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Dikarya"
] | [
923
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7872 | Domain of unknown function DUF7872 | DUF7872 | 1 |
IPR057195 | 57,195 | Protein of unknown function DUF7873 | DUF7873 | Family | 817 | false | false | This entry represents a family of uncharacterised actinobacterial proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25283"
] | [
"DUF7873"
] | [
817
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"metagenomes"
] | [
790,
13,
14
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF7873 | Protein of unknown function DUF7873 | DUF7873 | 5 |
IPR057196 | 57,196 | Protein of unknown function DUF7874 | DUF7874 | Family | 865 | false | false | This entry represents a group of uncharacterised plant proteins. They are predicted to adopt a non-compact structure composed of α-helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25284"
] | [
"DUF7874"
] | [
865
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Viridiplantae"
] | [
865
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
8,
7,
9
] | 3 | true | Family | Protein of unknown function DUF7874 | Protein of unknown function DUF7874 | DUF7874 | 6 |
IPR057197 | 57,197 | Domain of unknown function DUF7875 | DUF7875 | Domain | 547 | false | false | This entry represents a group of uncharacterised plant proteins. They are predicted to adopt a helical hairpin structure. | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF25285",
"PTHR36331"
] | [
"DUF7875",
""
] | [
547,
517
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
547
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
2,
2,
5
] | 3 | true | Domain | Domain of unknown function DUF7875 | Domain of unknown function DUF7875 | DUF7875 | 7 |
IPR057198 | 57,198 | Domain of unknown function DUF7876 | DUF7876 | Domain | 641 | false | false | This entry represents a domain found in a group of uncharacterised plant proteins. It is predicted to fold into an array of α-helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25286"
] | [
"DUF7876"
] | [
641
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Viridiplantae"
] | [
641
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
3,
8
] | 3 | true | Domain | Domain of unknown function DUF7876 | Domain of unknown function DUF7876 | DUF7876 | 5 |
IPR057199 | 57,199 | Domain of unknown function DUF7877 | DUF7877 | Domain | 1,035 | false | false | This is a presumed domain found in a group of uncharacterised fungal sequences. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25289"
] | [
"DUF7877"
] | [
1035
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1035
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF7877 | Domain of unknown function DUF7877 | DUF7877 | 8 |
IPR057200 | 57,200 | Domain of unknown function DUF7878 | DUF7878 | Domain | 472 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to contain two structural β(3)-α repeats that swap their α-helix in a similar way as observed in the known ssDNA-binding transcriptional regulator domains. It is likely that this domain is distantly related to them and probably represents the m... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25297"
] | [
"DUF7878"
] | [
472
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
472
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7878 | Domain of unknown function DUF7878 | DUF7878 | 6 |
IPR057201 | 57,201 | Protein of unknown function DUF7879 | DUF7879 | Family | 69 | false | false | This entry represents a family of virus proteins that is likely zinc binding. It shows structural similarity to . The function of these proteins is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25303"
] | [
"DUF7879"
] | [
69
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Viruses"
] | [
69
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF7879 | Protein of unknown function DUF7879 | DUF7879 | 4 |
IPR057202 | 57,202 | Domain of unknown function DUF7880 | DUF7880 | Domain | 757 | false | false | This entry represents a four helical bundle domain found in a range of uncharacterised proteins. This domain is sometimes found in proteins that also contain . Shows similarity to the PsbQ superfamily. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25306"
] | [
"DUF7880"
] | [
757
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
757
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
6,
3
] | 3 | true | Domain | Domain of unknown function DUF7880 | Domain of unknown function DUF7880 | DUF7880 | 8 |
IPR057203 | 57,203 | Domain of unknown function DUF7881 | DUF7881 | Domain | 610 | false | false | This entry represents a ubiquitin-like fold domain found in a range of bacterial proteins. These proteins usually have an adjacent HNH domain to the C terminus ( ). The function of this domain is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25324"
] | [
"DUF7881"
] | [
610
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Dikarya"
] | [
610
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7881 | Domain of unknown function DUF7881 | DUF7881 | 1 |
IPR057204 | 57,204 | Domain of unknown function DUF7882 | DUF7882 | Domain | 2,159 | false | false | This entry represents a family of uncharacterised proteins that are about 100 amino acids in length. These proteins are predicted to form homopentameric complexes. These proteins are found in actinomycete as well as a few phage genomes. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25355"
] | [
"DUF7882"
] | [
2159
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes"
] | [
2157,
2
] | 2 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7882 | Domain of unknown function DUF7882 | DUF7882 | 6 |
IPR057205 | 57,205 | Domain of unknown function DUF7883 | DUF7883 | Domain | 40 | false | false | This entry represents a domain of unknown function identified in Trypanosoma. Based on structural predictions, this domain is hypothesised to adopt a winged helix-turn-helix (HTH) fold. Winged helix DNA-binding proteins share a characteristic winged helix-turn-helix DNA-binding motif, in which the "wings", or loops, ar... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25367"
] | [
"DUF7883"
] | [
40
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00013195"
] | [
"10679470"
] | [
"Winged helix proteins."
] | [
2000
] | 1 | [] | [] | 0 | 0 | null | [
"Trypanosomatidae"
] | [
40
] | 1 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7883 | Domain of unknown function DUF7883 | DUF7883 | 7 |
IPR057206 | 57,206 | Domain of unknown function DUF7884 | DUF7884 | Domain | 4,542 | false | false | This domain is found in a group of uncharacterised bacterial proteins. It is usually found associated with methyltransferase domains such as and and is predicted to adopt an α-β configuration. It has a conserved motif F/YWDG. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25371"
] | [
"DUF7884"
] | [
4542
] | 1 | [] | [] | [] | 0 | [
"5z9o",
"7qos"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
4480,
10,
52
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7884 | Domain of unknown function DUF7884 | DUF7884 | 4 |
IPR057207 | 57,207 | F-box/LRR-repeat protein 15-like, leucin rich repeat domain | FBXL15_LRR | Domain | 35,501 | false | false | This domain represents a region of tandem leucine rich repeats found in human F-box/LRR-repeat protein 15 (FBXL15) and similar eukaryotic proteins. FBXL15 is the substrate recognition component of a SCF (SKP1-CUL1-F-box protein), an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent pr... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25372"
] | [
"LRR_FBXL15"
] | [
35501
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-8951664",
"R-BTA-983168",
"R-CEL-8951664",
"R-CEL-983168",
"R-CFA-8951664",
"R-CFA-983168",
"R-DRE-8854050",
"R-DRE-8951664",
"R-DRE-983168",
"R-HSA-3214842",
"R-HSA-8854050",
"R-HSA-8951664",
"R-HSA-9708530",
"R-HSA-983168",
"R-MMU-8854050",
"R-MMU-8951664",
"R-MMU-9708530",
... | [
"REACTOME:R-BTA-8951664",
"REACTOME:R-BTA-983168",
"REACTOME:R-CEL-8951664",
"REACTOME:R-CEL-983168",
"REACTOME:R-CFA-8951664",
"REACTOME:R-CFA-983168",
"REACTOME:R-DRE-8854050",
"REACTOME:R-DRE-8951664",
"REACTOME:R-DRE-983168",
"REACTOME:R-HSA-3214842",
"REACTOME:R-HSA-8854050",
"REACTOME:R-... | 20 | [
"5jh5",
"6o60",
"6w66",
"6wcq",
"8hcu",
"8uah",
"8ubt",
"8ubu",
"8ubv"
] | 9 | [
"PUB00033727",
"PUB00134229",
"PUB00147666",
"PUB00161596"
] | [
"16362057",
"17994099",
"21572392",
"26237645"
] | [
"Histone demethylation by a family of JmjC domain-containing proteins.",
"JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes.",
"SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.",
"Local generation of fumarate promotes ... | [
2006,
2007,
2011,
2015
] | 4 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Viruses",
"ecological metagenomes"
] | [
293,
35172,
27,
9
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
99,
1,
36,
20,
38,
26,
2,
65,
59,
1,
122
] | 11 | true | Domain | F-box/LRR-repeat protein 15-like, leucin rich repeat domain | F-box/LRR-repeat protein 15-like, leucin rich repeat domain | FBXL15_LRR | 1 |
IPR057208 | 57,208 | Domain of unknown function DUF7886 | DUF7886 | Domain | 465 | false | false | This domain is found in uncharacterised proteins from animals and plants. It is predicted to adopt an unique complex α/β structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25377"
] | [
"DUF7886"
] | [
465
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
465
] | 1 | [
"Danio rerio"
] | [
6
] | 1 | true | Domain | Domain of unknown function DUF7886 | Domain of unknown function DUF7886 | DUF7886 | 9 |
IPR057209 | 57,209 | Domain of unknown function DUF7887 | DUF7887 | Domain | 493 | false | false | This domain is found in uncharacterised plant proteins. It is predicted to contain two transmembrane helices. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25397"
] | [
"DUF7887"
] | [
493
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
493
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
2,
3,
2
] | 3 | true | Domain | Domain of unknown function DUF7887 | Domain of unknown function DUF7887 | DUF7887 | 2 |
IPR057213 | 57,213 | Domain of unknown function DUF7891 | DUF7891 | Domain | 1,075 | false | false | This domain is found in a group of uncharacterised fungal sequences that also contain . It has a conserved I/LWG motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25421"
] | [
"DUF7891"
] | [
1075
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Fungi"
] | [
1075
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF7891 | Domain of unknown function DUF7891 | DUF7891 | 6 |
IPR057214 | 57,214 | Domain of unknown function DUF7892 | DUF7892 | Domain | 723 | false | false | This predicted domain is found in a group of uncharacterised fungal proteins that also contain an F-box domain. This domain is predicted to adopt a winged helix fold. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25422"
] | [
"DUF7892"
] | [
723
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
723
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF7892 | Domain of unknown function DUF7892 | DUF7892 | 7 |
IPR057215 | 57,215 | Domain of unknown function DUF7893 | DUF7893 | Domain | 782 | false | false | This predicted winged helix domain is found in a group of uncharacterised fungal proteins. It is often found associated with . | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25423"
] | [
"DUF7893"
] | [
782
] | 1 | [] | [] | [] | 0 | [
"9bap",
"9baq",
"9baz"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Fungi"
] | [
782
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF7893 | Domain of unknown function DUF7893 | DUF7893 | 3 |
IPR057216 | 57,216 | Domain of unknown function DUF7894 | DUF7894 | Domain | 493 | false | false | This domain is found in uncharacterised plant proteins. It is predicted to fold into a α/β structure with a central mixed β-sheet and α-helices packed on both sides. The predicted structure has a topological similarity to PACT family domains members of . | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF25428",
"PTHR37221"
] | [
"DUF7894",
""
] | [
493,
477
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Embryophyta"
] | [
493
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
3,
5,
6
] | 3 | true | Domain | Domain of unknown function DUF7894 | Domain of unknown function DUF7894 | DUF7894 | 9 |
IPR057217 | 57,217 | Domain of unknown function DUF7895 | DUF7895 | Domain | 499 | false | false | This domain is found in uncharacterised plant proteins. It contains four pairs of highly conserved cysteine residues that may be involved in metal coordination. It also contains a highly conserved CxxCxGxG sequence motif. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25433"
] | [
"DUF7895"
] | [
499
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Methanobacterium bryantii",
"Streptophyta"
] | [
1,
498
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
3,
9
] | 3 | true | Domain | Domain of unknown function DUF7895 | Domain of unknown function DUF7895 | DUF7895 | 1 |
IPR057218 | 57,218 | Domain of unknown function DUF7896 | DUF7896 | Domain | 1,661 | false | false | This domain is found in uncharacterised proteins from fungi. It contains two pairs of conserved cysteine and histidine residues that may be involved in metal coordination. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25438"
] | [
"DUF7896"
] | [
1661
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
1661
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
2
] | 1 | true | Domain | Domain of unknown function DUF7896 | Domain of unknown function DUF7896 | DUF7896 | 8 |
IPR057219 | 57,219 | Domain of unknown function DUF7897 | DUF7897 | Domain | 468 | false | false | This domain is found in uncharacterised proteins predominantly from bacteria. It is predicted to adopt a complex α/β structure. | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF033805",
"PF25448"
] | [
"invasion_CiaB",
"DUF7897"
] | [
410,
468
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00105340",
"PUB00105341",
"PUB00105342"
] | [
"10361274",
"16629018",
"24426164"
] | [
"Bacterial secreted proteins are required for the internaliztion of Campylobacter jejuni into cultured mammalian cells.",
"Adherence to and invasion of human intestinal epithelial cells by Campylobacter jejuni and Campylobacter coli isolates from retail meat products.",
"Identification and Characterization of a... | [
1999,
2006,
2014
] | 3 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
437,
18,
13
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7897 | Domain of unknown function DUF7897 | DUF7897 | 1 |
IPR057220 | 57,220 | Domain of unknown function DUF7898 | DUF7898 | Domain | 1,622 | false | false | This entry describes the N-terminal domain of unknown function of DNA polymerase theta subunit (PolQ) majoritarily from fungal and and yeast proteins. Structural predictions suggest that this family adopts Helix-Helix-Helix (HHH) motifs. Proteins containing HHH motifs are typically associated with DNA-binding functions... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25453"
] | [
"DUF7898"
] | [
1622
] | 1 | [
"REACTOME"
] | [
"R-HSA-5685939"
] | [
"REACTOME:R-HSA-5685939"
] | 1 | [
"5a9f",
"5a9j",
"5aga",
"8w0a",
"9asj",
"9ask",
"9asl",
"9bh6",
"9bh7",
"9bh8",
"9bh9",
"9bha",
"9bp9",
"9bpa",
"9c5q",
"9osw",
"9osy"
] | 17 | [
"PUB00021052",
"PUB00101275"
] | [
"10908318",
"26636256"
] | [
"Common fold in helix-hairpin-helix proteins.",
"Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway."
] | [
2000,
2015
] | 2 | [] | [] | 0 | 0 | null | [
"Candidatus Acidifodinimicrobium mancum",
"Eukaryota",
"Sphaerochaeta associata"
] | [
1,
1620,
1
] | 3 | [
"Arabidopsis thaliana",
"Homo sapiens",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
4,
4,
1
] | 3 | true | Domain | Domain of unknown function DUF7898 | Domain of unknown function DUF7898 | DUF7898 | 5 |
IPR057221 | 57,221 | Repeat of unknown function DUF7899 | DUF7899 | Repeat | 1,883 | false | false | This domain is found in uncharacterised plant proteins. It is predicted to adopt an eight-bladed β-propeller. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25463"
] | [
"DUF7899"
] | [
1883
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1883
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
10,
17,
36
] | 3 | true | Repeat | Repeat of unknown function DUF7899 | Repeat of unknown function DUF7899 | DUF7899 | 8 |
IPR057222 | 57,222 | Domain of unknown function DUF7900 | DUF7900 | Domain | 283 | false | false | This domain is found at the C-terminal end of a group of uncharacterised plant proteins. It is often found associated to . It has a conserved motif GWQK. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25464"
] | [
"DUF7900"
] | [
283
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Amycolatopsis bullii",
"Pentapetalae"
] | [
1,
282
] | 2 | [
"Arabidopsis thaliana"
] | [
8
] | 1 | true | Domain | Domain of unknown function DUF7900 | Domain of unknown function DUF7900 | DUF7900 | 2 |
IPR057223 | 57,223 | Domain of unknown function DUF7901 | DUF7901 | Domain | 76 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to adopt a β-sandwich structure with significant topological similarity to known galactose-binding domains, in particular to lectin-like domain of the Cwp84, a surface layer associated protein of Clostridium difficile. It is likely that this do... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25470"
] | [
"DUF7901"
] | [
76
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanomicrobia",
"ecological metagenomes"
] | [
48,
3,
25
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7901 | Domain of unknown function DUF7901 | DUF7901 | 8 |
IPR057224 | 57,224 | Domain of unknown function DUF7902 | DUF7902 | Domain | 1,979 | false | false | This domain is found in uncharacterised bacterial proteins. It is predicted to adopt a three-helical bundle with some topological similarity to spectrin. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25472"
] | [
"DUF7902"
] | [
1979
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"ecological metagenomes"
] | [
1969,
3,
7
] | 3 | [] | [] | 0 | true | Domain | Domain of unknown function DUF7902 | Domain of unknown function DUF7902 | DUF7902 | 7 |
IPR057225 | 57,225 | Domain of unknown function DUF7903 | DUF7903 | Domain | 1,206 | false | false | This domain is found in uncharacterised plant proteins. It has detectable similarity to members of the CYTH-like phosphatase superfamily and it is predicted to adopt similar structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25475"
] | [
"DUF7903"
] | [
1206
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Streptophytina"
] | [
1206
] | 1 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
11,
3,
9
] | 3 | true | Domain | Domain of unknown function DUF7903 | Domain of unknown function DUF7903 | DUF7903 | 3 |
IPR057226 | 57,226 | Domain of unknown function DUF7904 | DUF7904 | Domain | 1,241 | false | false | This gelsolin-like domain is found in a group of uncharacterised fungal proteins. Its function is unknown. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25480"
] | [
"DUF7904"
] | [
1241
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00000950",
"PUB00025486",
"PUB00029181",
"PUB00030660",
"PUB00040658"
] | [
"9288746",
"12460571",
"12742020",
"15215896",
"16469333"
] | [
"The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation.",
"The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complex.",
"Gelsolin domains 4-6 in active, actin-free conformation identifies sites of regulatory calcium ions.",
"Stru... | [
1997,
2002,
2003,
2004,
2006
] | 5 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1241
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)"
] | [
1
] | 1 | true | Domain | Domain of unknown function DUF7904 | Domain of unknown function DUF7904 | DUF7904 | 3 |
IPR057227 | 57,227 | Domain of unknown function DUF7905 | DUF7905 | Domain | 1,099 | false | false | This domain is found in the Uncharacterized protein C582.04c from Schizosaccharomyces pombe and related proteins. It has detectable similarity to domains members of the CYTH-like phosphatase superfamily and it is predicted to adopt a similar structure. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF25482"
] | [
"DUF7905"
] | [
1099
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Opisthokonta"
] | [
1099
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)"
] | [
1,
1
] | 2 | true | Domain | Domain of unknown function DUF7905 | Domain of unknown function DUF7905 | DUF7905 | 8 |
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