interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR005758 | 5,758 | UDP-N-acetylmuramate--L-alanine ligase | UDP-N-AcMur_Ala_ligase_MurC | Family | 25,283 | false | false | This entry represents UDP-N-acetylmuramate-alanine ligase (MurC). MurC is an essential, cytoplasmic peptidoglycan biosynthetic enzyme, catalyzes the ATP-dependent ligation of L-alanine (Ala) and UDP-N-acetylmuramic acid (UNAM) to form UDP-N-acetylmuramyl-L-alanine (UNAM-Ala). The enzyme is a nonribosomal peptide ligase... | [
"GO:0008763"
] | [
"UDP-N-acetylmuramate-L-alanine ligase activity"
] | [
"molecular_function"
] | 1 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_00046",
"TIGR01082"
] | [
"MurC",
"murC"
] | [
24141,
25054
] | 2 | [
"EC",
"GP",
"METACYC",
"METACYC",
"METACYC"
] | [
"6.3.2.8",
"GenProp1448",
"PWY-6386",
"PWY-6387",
"PWY-7953"
] | [
"EC:6.3.2.8",
"GP:GenProp1448",
"METACYC:PWY-6386",
"METACYC:PWY-6387",
"METACYC:PWY-7953"
] | 5 | [
"1gqq",
"1gqy",
"1j6u",
"1p31",
"1p3d",
"2f00",
"4hv4",
"5vvw",
"6cau",
"6x9f",
"6x9n",
"7bva",
"7bvb",
"8dof",
"8egm",
"8egn",
"8ewa",
"9d9k",
"9d9m",
"9ir5",
"9ir6",
"9s8i"
] | 22 | [
"PUB00035788",
"PUB00035789",
"PUB00035790",
"PUB00035791",
"PUB00035792",
"PUB00101154"
] | [
"17139082",
"17427948",
"16595662",
"16322581",
"16934839",
"18974047"
] | [
"Structure of Escherichia coli UDP-N-acetylmuramoyl:L-alanine ligase (MurC).",
"Targeted molecular dynamics simulation studies of binding and conformational changes in E. coli MurD.",
"The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity.",
"Structure of MurF from S... | [
2006,
2007,
2006,
2005,
2006,
2008
] | 6 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Methanophaga sp. ANME-1 ERB7",
"Eukaryota",
"unclassified sequences"
] | [
24605,
1,
240,
437
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | UDP-N-acetylmuramate--L-alanine ligase | UDP-N-acetylmuramate--L-alanine ligase | UDP-N-AcMur_Ala_ligase_MurC | 8 |
IPR005759 | 5,759 | Endonuclease III | Nth | Family | 24,790 | false | false | The spectrum of DNA damage caused by reactive oxygen species includes a wide variety of modifications of purine and pyrimidine bases. Among these modified bases, 7,8-dihydro-8-oxoguanine (8-oxoG) is an important mutagenic lesion. Base excision repair is a critical mechanism for preventing mutations by removing the oxid... | [
"GO:0003906",
"GO:0006284"
] | [
"DNA-(apurinic or apyrimidinic site) endonuclease activity",
"base-excision repair"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_00942",
"TIGR01083"
] | [
"Nth",
"nth"
] | [
24752,
22497
] | 2 | [
"EC"
] | [
"4.2.99.18"
] | [
"EC:4.2.99.18"
] | 1 | [
"1orn",
"1orp",
"1p59",
"2abk"
] | 4 | [
"PUB00007891"
] | [
"11328882"
] | [
"Escherichia coli Nth and human hNTH1 DNA glycosylases are involved in removal of 8-oxoguanine from 8-oxoguanine/guanine mispairs in DNA."
] | [
2001
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Siphoviridae sp. ctBLh2",
"unclassified sequences"
] | [
753,
23540,
68,
1,
428
] | 5 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Endonuclease III | Endonuclease III | Nth | 8 |
IPR005760 | 5,760 | A/G-specific adenine glycosylase MutY | A/G_AdeGlyc_MutY | Family | 16,606 | false | false | The DNA repair enzyme MutY plays an important role in the prevention of DNA mutations resulting from the presence of the oxidatively damaged lesion 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-OxoG). 8-OxoG can mispair with 2'-deoxycytidine 5'-triphosphate or with 2'-deoxyadenosine triphosphate during DNA replication, formin... | [
"GO:0019104",
"GO:0006284"
] | [
"DNA N-glycosylase activity",
"base-excision repair"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01084"
] | [
"mutY"
] | [
16606
] | 1 | [
"EC",
"GP",
"REACTOME",
"REACTOME"
] | [
"3.2.2.31",
"GenProp1099",
"R-RNO-110331",
"R-RNO-110357"
] | [
"EC:3.2.2.31",
"GP:GenProp1099",
"REACTOME:R-RNO-110331",
"REACTOME:R-RNO-110357"
] | 4 | [
"1kg2",
"1kg3",
"1kg4",
"1kg5",
"1kg6",
"1kg7",
"1kqj",
"1mud",
"1mun",
"1muy",
"1rrq",
"1rrs",
"1vrl",
"1wef",
"1weg",
"1wei",
"3g0q",
"4yoq",
"4yph",
"4ypr",
"5kn8",
"5kn9",
"6q0c",
"6u7t",
"7ef8",
"7ef9",
"8dvp",
"8dvy",
"8dw0",
"8dw4",
"8dw7",
"8dwd"... | 35 | [
"PUB00014091",
"PUB00068370",
"PUB00068371"
] | [
"14618256",
"10684930",
"2682664"
] | [
"Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis.",
"Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria.",
"Escherichia coli mutY gene encodes an adenine ... | [
2003,
2000,
1989
] | 3 | [
"IPR044298"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
11,
16099,
344,
152
] | 4 | [
"Escherichia coli (strain K12)",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus"
] | [
1,
1,
1,
3
] | 4 | true | Family | A/G-specific adenine glycosylase MutY | A/G-specific adenine glycosylase MutY | A/G_AdeGlyc_MutY | 7 |
IPR005761 | 5,761 | UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase | UDP-N-AcMur-Glu-dNH2Pim_ligase | Family | 28,430 | false | false | This entry represents DP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligases (MurE; ). An exception is found with Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is ( ). The Mycobacteria, part of the closest neighbouring branch outside of the low-GC Gram-po... | [
"GO:0005524",
"GO:0016881",
"GO:0008360",
"GO:0051301",
"GO:0005737"
] | [
"ATP binding",
"acid-amino acid ligase activity",
"regulation of cell shape",
"cell division",
"cytoplasm"
] | [
"molecular_function",
"molecular_function",
"biological_process",
"biological_process",
"cellular_component"
] | 5 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_00208",
"TIGR01085"
] | [
"MurE",
"murE"
] | [
26309,
28332
] | 2 | [
"EC",
"EC",
"GP",
"METACYC",
"METACYC"
] | [
"6.3.2",
"6.3.2.13",
"GenProp1448",
"PWY-6387",
"PWY-7953"
] | [
"EC:6.3.2",
"EC:6.3.2.13",
"GP:GenProp1448",
"METACYC:PWY-6387",
"METACYC:PWY-7953"
] | 5 | [
"1e8c",
"2wtz",
"2xja",
"4bub",
"4c12",
"4c13",
"7b53",
"7b60",
"7b61",
"7b68",
"7b6g",
"7b6i",
"7b6j",
"7b6k",
"7b6l",
"7b6m",
"7b6n",
"7b6o",
"7b6p",
"7b6q",
"7b9e",
"7b9w",
"7d27",
"8f5d",
"8g6p",
"8qma",
"8r5o",
"8r6s",
"8ras",
"8rdj",
"8w9z",
"8wa0"... | 35 | [
"PUB00035788",
"PUB00035789",
"PUB00035790",
"PUB00035791",
"PUB00035792",
"PUB00101154"
] | [
"17139082",
"17427948",
"16595662",
"16322581",
"16934839",
"18974047"
] | [
"Structure of Escherichia coli UDP-N-acetylmuramoyl:L-alanine ligase (MurC).",
"Targeted molecular dynamics simulation studies of binding and conformational changes in E. coli MurD.",
"The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity.",
"Structure of MurF from S... | [
2006,
2007,
2006,
2005,
2006,
2008
] | 6 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"unclassified sequences"
] | [
27226,
684,
2,
518
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
1,
2,
3
] | 4 | true | Family | UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase | UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase | UDP-N-AcMur-Glu-dNH2Pim_ligase | 6 |
IPR005762 | 5,762 | UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD | MurD | Family | 27,497 | false | false | The bacterial cell wall provides strength and rigidity to counteract internal osmotic pressure, and protection against the environment. The peptidoglycan layer gives the cell wall its strength, and helps maintain the overall shape of the cell. The basic peptidoglycan structure of both Gram-positive and Gram-negative ba... | [
"GO:0005524",
"GO:0008764",
"GO:0008360",
"GO:0051301",
"GO:0005737"
] | [
"ATP binding",
"UDP-N-acetylmuramoylalanine-D-glutamate ligase activity",
"regulation of cell shape",
"cell division",
"cytoplasm"
] | [
"molecular_function",
"molecular_function",
"biological_process",
"biological_process",
"cellular_component"
] | 5 | [
"HAMAP",
"PANTHER",
"NCBIFAM"
] | [
"MF_00639",
"PTHR43692",
"TIGR01087"
] | [
"MurD",
"",
"murD"
] | [
25808,
27483,
26051
] | 3 | [
"EC",
"GP",
"METACYC",
"METACYC"
] | [
"6.3.2.9",
"GenProp1448",
"PWY-6386",
"PWY-6387"
] | [
"EC:6.3.2.9",
"GP:GenProp1448",
"METACYC:PWY-6386",
"METACYC:PWY-6387"
] | 4 | [
"1e0d",
"1eeh",
"1uag",
"2jff",
"2jfg",
"2jfh",
"2uag",
"2uuo",
"2uup",
"2vtd",
"2vte",
"2wjp",
"2x5o",
"2xpc",
"2y1o",
"2y66",
"2y67",
"2y68",
"3lk7",
"3uag",
"4buc",
"4uag",
"5a5e",
"5a5f",
"7sir",
"7sy9",
"7ti7",
"7u35",
"8dp2",
"8v8w",
"8v8x",
"8v8y"... | 38 | [
"PUB00035788",
"PUB00035789",
"PUB00035790",
"PUB00035791",
"PUB00035792",
"PUB00101154"
] | [
"17139082",
"17427948",
"16595662",
"16322581",
"16934839",
"18974047"
] | [
"Structure of Escherichia coli UDP-N-acetylmuramoyl:L-alanine ligase (MurC).",
"Targeted molecular dynamics simulation studies of binding and conformational changes in E. coli MurD.",
"The MurE synthetase from Thermotoga maritima is endowed with an unusual D-lysine adding activity.",
"Structure of MurF from S... | [
2006,
2007,
2006,
2005,
2006,
2008
] | 6 | [] | [
"IPR043687"
] | 0 | 1 | 0 | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"unclassified Caudoviricetes",
"unclassified sequences"
] | [
26270,
392,
105,
3,
727
] | 5 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD | UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD | MurD | 9 |
IPR005763 | 5,763 | L-fucose isomerase | Fucose_isomerase | Family | 4,043 | false | false | L-fucose isomerase ( ) converts the aldose L-fucose into the corresponding ketose L-fuculose during the first step in fucose metabolism using Mn2+ as a cofactor. The enzyme is a hexamer, forming the largest structurally known ketol isomerase, and has no sequence or structural similarity with other ketol isomerases. L-f... | [
"GO:0008736",
"GO:0030145",
"GO:0019317",
"GO:0005737"
] | [
"L-fucose isomerase activity",
"manganese ion binding",
"fucose catabolic process",
"cytoplasm"
] | [
"molecular_function",
"molecular_function",
"biological_process",
"cellular_component"
] | 4 | [
"HAMAP",
"PANTHER",
"NCBIFAM"
] | [
"MF_01254",
"PTHR37840",
"TIGR01089"
] | [
"Fucose_iso",
"",
"fucI"
] | [
2522,
4043,
2525
] | 3 | [
"EC",
"GP",
"GP",
"GP"
] | [
"5.3.1.25",
"GenProp0458",
"GenProp1589",
"GenProp1680"
] | [
"EC:5.3.1.25",
"GP:GenProp0458",
"GP:GenProp1589",
"GP:GenProp1680"
] | 4 | [
"1fui",
"3a9r",
"3a9s",
"3a9t",
"4c20",
"4c21",
"4c22",
"6k1f",
"6k1g"
] | 9 | [
"PUB00007428"
] | [
"9367760"
] | [
"Structure and mechanism of L-fucose isomerase from Escherichia coli."
] | [
1997
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
9,
3888,
39,
107
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | L-fucose isomerase | L-fucose isomerase | Fucose_isomerase | 2 |
IPR005764 | 5,764 | Adenine phosphoribosyl transferase | Ade_phspho_trans | Family | 24,935 | false | false | Adenine phosphoribosyltransferase (APRTase, ) is a widely distributed enzyme, and its deficiency in humans causes the accumulation of 2,8-dihydroxyadenine. It is the sole catalyst for adenine recycling in most eukaryotes. AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate | [
"GO:0003999",
"GO:0006168",
"GO:0005737"
] | [
"adenine phosphoribosyltransferase activity",
"adenine salvage",
"cytoplasm"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_00004",
"TIGR01090"
] | [
"Aden_phosphoribosyltr",
"apt"
] | [
24926,
20991
] | 2 | [
"EC",
"GP",
"GP",
"GP",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.4.2.7",
"GenProp1268",
"GenProp1430",
"GenProp1630",
"PWY-6605",
"PWY-6610",
"PWY-7805",
"PWY-7807",
"R-CEL-6798695",
"R-CEL-74217",
"R-DME-6798695",
"R-DME-74217",
"R-HSA-6798695",
"R-HSA-74217",
"R-HSA-9734195",
"R-MMU-6798695",
"R-MMU-74217",
"R-RNO-6798695",
"R-RNO-74217",... | [
"EC:2.4.2.7",
"GP:GenProp1268",
"GP:GenProp1430",
"GP:GenProp1630",
"METACYC:PWY-6605",
"METACYC:PWY-6610",
"METACYC:PWY-7805",
"METACYC:PWY-7807",
"REACTOME:R-CEL-6798695",
"REACTOME:R-CEL-74217",
"REACTOME:R-DME-6798695",
"REACTOME:R-DME-74217",
"REACTOME:R-HSA-6798695",
"REACTOME:R-HSA-... | 23 | [
"1g2p",
"1g2q",
"1ore",
"1zn7",
"1zn8",
"1zn9",
"2dy0",
"4lza",
"4m0k",
"4mb6",
"4x44",
"4x45",
"5b6h",
"5vjn",
"5vjp",
"5y07",
"5y4a",
"5yw2",
"5yw5",
"5zc7",
"5zmi",
"5znq",
"5zoc",
"6fch",
"6fci",
"6fcl",
"6fd4",
"6fd5",
"6fd6",
"6hgp",
"6hgq",
"6hgr"... | 36 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
119,
19327,
5142,
3,
344
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
22,
1,
1,
2,
1,
1,
1,
1,
14,
4,
1,
1,
23
] | 13 | true | Family | Adenine phosphoribosyl transferase | Adenine phosphoribosyl transferase | Ade_phspho_trans | 8 |
IPR005765 | 5,765 | Uracil phosphoribosyl transferase | UPRT | Family | 19,186 | false | false | The enzyme uracil phosphoribosyltransferase (UPRT, ) catalyzes conversion of uracil to uridine 5'-monophosphate utilizing 5'-phosphoribosyl--1-pyrophosphate (PRPP). UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate | [
"GO:0004845",
"GO:0006223"
] | [
"uracil phosphoribosyltransferase activity",
"uracil salvage"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01091"
] | [
"upp"
] | [
19186
] | 1 | [
"EC",
"GP",
"GP",
"GP",
"METACYC"
] | [
"2.4.2.9",
"GenProp1307",
"GenProp1361",
"GenProp1369",
"PWY-7183"
] | [
"EC:2.4.2.9",
"GP:GenProp1307",
"GP:GenProp1361",
"GP:GenProp1369",
"METACYC:PWY-7183"
] | 5 | [
"1i5e",
"1o5o",
"1v9s",
"1vst",
"1xtt",
"1xtu",
"1xtv",
"2e55",
"2ehj",
"3dmp",
"3g6w",
"5e38",
"6wn8"
] | 13 | [] | [] | [] | [] | 0 | [] | [
"IPR034331",
"IPR034332"
] | 0 | 2 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
536,
17755,
666,
229
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
3,
1,
3,
4
] | 4 | true | Family | Uracil phosphoribosyl transferase | Uracil phosphoribosyl transferase | UPRT | 3 |
IPR005766 | 5,766 | Delta l-pyrroline-5-carboxylate synthetase | P5_carboxy_syn | Family | 3,978 | false | false | Delta l-pyrroline-5-carboxylate synthetase contains a glutamate 5-kinase (ProB, ) region followed by a gamma-glutamyl phosphate reductase (ProA, ) region and catalyses the first and second steps in proline biosynthesis. | [
"GO:0003824",
"GO:0055129"
] | [
"catalytic activity",
"L-proline biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PIRSF",
"NCBIFAM"
] | [
"PIRSF036429",
"TIGR01092"
] | [
"P5C_syn",
"P5CS"
] | [
3797,
3709
] | 2 | [
"EC",
"EC",
"GP",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"1.2.1.41",
"2.7.2.11",
"GenProp1472",
"PWY-6922",
"R-CEL-8964539",
"R-CEL-9837999",
"R-HSA-8964539",
"R-HSA-9837999",
"R-MMU-8964539",
"R-MMU-9837999"
] | [
"EC:1.2.1.41",
"EC:2.7.2.11",
"GP:GenProp1472",
"METACYC:PWY-6922",
"REACTOME:R-CEL-8964539",
"REACTOME:R-CEL-9837999",
"REACTOME:R-HSA-8964539",
"REACTOME:R-HSA-9837999",
"REACTOME:R-MMU-8964539",
"REACTOME:R-MMU-9837999"
] | 10 | [
"2h5g",
"7f5t",
"7f5u",
"7f5v",
"7f5x",
"7wx3",
"7wx4",
"7wxf",
"7wxg",
"7wxh",
"7wxi",
"8j0e",
"8j0f",
"8j0g",
"8j27",
"8j28",
"8y2h"
] | 17 | [] | [] | [] | [] | 0 | [
"IPR005715"
] | [] | 1 | 0 | 1 | [
"Eukaryota"
] | [
3978
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
11,
1,
4,
1,
1,
4,
4,
2,
27
] | 9 | true | Family | Delta l-pyrroline-5-carboxylate synthetase | Delta l-pyrroline-5-carboxylate synthetase | P5_carboxy_syn | 6 |
IPR005768 | 5,768 | Specific amino acids and opine-binding periplasmic protein, ABC transporter | Lys_Arg_Orn-bd | Family | 8,901 | false | false | Bacterial high affinity transport systems are involved in active transport of solutes across the cytoplasmic membrane. Most of the bacterial ABC (ATP-binding cassette) importers are composed of one or two transmembrane permease proteins, one or two nucleotide-binding proteins and a highly specific periplasmic solute-bi... | [
"GO:0071705",
"GO:0030288"
] | [
"nitrogen compound transport",
"outer membrane-bounded periplasmic space"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01096"
] | [
"3A0103s03R"
] | [
8901
] | 1 | [] | [] | [] | 0 | [
"1hpb",
"1hsl",
"1laf",
"1lag",
"1lah",
"1lst",
"2lao",
"2m8c",
"4p0i",
"4pow",
"4pp0",
"4zv1",
"4zv2",
"5ito",
"5itp",
"5ore",
"5org",
"5ot8",
"5ot9",
"5ota",
"5otc",
"5ovz",
"5owf",
"6ft2",
"6mku",
"6mkw",
"6mkx",
"6ml0",
"6ml9",
"6mla",
"6mld",
"6mle"... | 39 | [
"PUB00071925",
"PUB00071938",
"PUB00072609",
"PUB00087511"
] | [
"18310026",
"8003968",
"9520394",
"27801902"
] | [
"Characterization of a Pseudomonas putida ABC transporter (AatJMQP) required for acidic amino acid uptake: biochemical properties and regulation by the Aau two-component system.",
"Sequence relationships between integral inner membrane proteins of binding protein-dependent transport systems: evolution by recurren... | [
2008,
1994,
1998,
2017
] | 4 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"hydrothermal vent metagenome"
] | [
8893,
7,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
4
] | 1 | true | Family | Specific amino acids and opine-binding periplasmic protein, ABC transporter | Specific amino acids and opine-binding periplasmic protein, ABC transporter | Lys_Arg_Orn-bd | 2 |
IPR005769 | 5,769 | ABC transporter, permease PhnE/PtxC | PhnE/PtxC | Family | 14,294 | false | false | This entry includes a group of ABC transport system permeases, such as PtxC from Pseudomonas stutzeri and PhnE from Mycobacterium smegmatis. PhnE is part of the ABC transporter complex PhnCDE involved in phosphate import [ ]. | [
"GO:0015416",
"GO:0015716",
"GO:0005886"
] | [
"ABC-type phosphonate transporter activity",
"organic phosphonate transport",
"plasma membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"NCBIFAM"
] | [
"TIGR01097"
] | [
"PhnE"
] | [
14294
] | 1 | [
"GP",
"GP"
] | [
"GenProp0232",
"GenProp0236"
] | [
"GP:GenProp0232",
"GP:GenProp0236"
] | 2 | [] | 0 | [
"PUB00043017",
"PUB00070841"
] | [
"17074913",
"9791102"
] | [
"The Phn system of Mycobacterium smegmatis: a second high-affinity ABC-transporter for phosphate.",
"Molecular genetic analysis of phosphite and hypophosphite oxidation by Pseudomonas stutzeri WM88."
] | [
2006,
1998
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
445,
13722,
10,
117
] | 4 | [] | [] | 0 | true | Family | ABC transporter, permease PhnE/PtxC | ABC transporter, permease PhnE/PtxC | PhnE/PtxC | 1 |
IPR005770 | 5,770 | Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein | PhnD | Family | 11,744 | false | false | This family includes the periplasmic binding protein component of ABC transporters for phosphonates [ ] as well as other related binding components for closely related substances such as phosphate [ ] and phosphite [ ]. A number of members of this family are found in genomic contexts with components of selenium metabol... | [
"GO:0055085",
"GO:0043190"
] | [
"transmembrane transport",
"ATP-binding cassette (ABC) transporter complex"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01098"
] | [
"3A0109s03R"
] | [
11744
] | 1 | [] | [] | [] | 0 | [
"3n5l",
"3p7i",
"3qk6",
"3quj",
"3s4u",
"5jvb",
"5lq1",
"5lq5",
"5lq8",
"5lv1",
"5me4",
"5o2j",
"5o2k",
"5o37",
"6emn",
"6ghq",
"6ght",
"6x6b",
"6x8w",
"6x9g",
"6xab",
"6xad",
"6xl2",
"7l22",
"7s6g",
"7zck"
] | 26 | [
"PUB00042957",
"PUB00043017",
"PUB00043018",
"PUB00043019"
] | [
"16751609",
"17074913",
"15317793",
"8335257"
] | [
"Identification of cognate ligands for the Escherichia coli phnD protein product and engineering of a reagentless fluorescent biosensor for phosphonates.",
"The Phn system of Mycobacterium smegmatis: a second high-affinity ABC-transporter for phosphate.",
"The htx and ptx operons of Pseudomonas stutzeri WM88 ar... | [
2006,
2006,
2004,
1993
] | 4 | [] | [
"IPR017797",
"IPR030836"
] | 0 | 2 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
255,
11336,
14,
139
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein | Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein | PhnD | 4 |
IPR005771 | 5,771 | UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type | GalU_uridylyltTrfase_bac/arc | Family | 26,909 | false | false | Uridine 5'-triphosphate:glucose-1-phosphate uridylyltransferase (uridine diphosphoglucose pyrophosphorylase, ) is responsible for the synthesis of UDP-glucose, a key compound in the biosynthesis of polysaccharides. Glucose is fermented through the glycolysis step to pyruvate, which in turn is converted to lactate. The ... | [
"GO:0003983",
"GO:0006011"
] | [
"UTP:glucose-1-phosphate uridylyltransferase activity",
"UDP-alpha-D-glucose metabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PANTHER",
"NCBIFAM",
"CDD"
] | [
"PTHR43197",
"TIGR01099",
"cd02541"
] | [
"",
"galU",
"UGPase_prokaryotic"
] | [
26903,
19543,
23915
] | 3 | [
"EC",
"GP",
"GP",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"
] | [
"2.7.7.9",
"GenProp1648",
"GenProp1743",
"PWY-3801",
"PWY-6527",
"PWY-7238",
"PWY-7343",
"PWY-7817"
] | [
"EC:2.7.7.9",
"GP:GenProp1648",
"GP:GenProp1743",
"METACYC:PWY-3801",
"METACYC:PWY-6527",
"METACYC:PWY-7238",
"METACYC:PWY-7343",
"METACYC:PWY-7817"
] | 8 | [
"2e3d",
"2pa4",
"2ux8",
"3juj",
"3juk",
"4d48",
"5i1f",
"5j49",
"5vct",
"5ve7",
"6ikx",
"6ikz",
"6k8d",
"6knj",
"6knl",
"6mnu",
"7b1r",
"7o2n",
"8b31",
"8b68",
"8b6d",
"8f73",
"9o90",
"9yfb",
"9yfi",
"9yfk",
"9ygk"
] | 27 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacillus phage SP-15",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
420,
1,
25991,
107,
390
] | 5 | [
"Escherichia coli (strain K12)"
] | [
2
] | 1 | true | Family | UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type | UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type | GalU_uridylyltTrfase_bac/arc | 2 |
IPR005772 | 5,772 | ATPase, V1 complex, subunit F, eukaryotic | ATPase_V1-cplx_fsu_euk | Family | 4,117 | false | false | Transmembrane ATPases are membrane-bound enzyme complexes/ion transporters that use ATP hydrolysis to drive the transport of protons across a membrane. Some transmembrane ATPases also work in reverse, harnessing the energy from a proton gradient, using the flux of ions across the membrane via the ATPase proton channel ... | [
"GO:0046961",
"GO:1902600",
"GO:0033180"
] | [
"proton-transporting ATPase activity, rotational mechanism",
"proton transmembrane transport",
"proton-transporting V-type ATPase, V1 domain"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PIRSF",
"NCBIFAM"
] | [
"PIRSF015945",
"TIGR01101"
] | [
"ATPase_V1_F_euk",
"V_ATP_synt_F"
] | [
3608,
4051
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-1222556",
"R-BTA-77387",
"R-BTA-917977",
"R-BTA-9639288",
"R-BTA-983712",
"R-CEL-1222556",
"R-CEL-77387",
"R-CEL-917977",
"R-CEL-9639288",
"R-CEL-983712",
"R-DDI-1222556",
"R-DDI-77387",
"R-DDI-917977",
"R-DDI-9639288",
"R-DME-1222556",
"R-DME-77387",
"R-DME-917977",
"R-DME-... | [
"REACTOME:R-BTA-1222556",
"REACTOME:R-BTA-77387",
"REACTOME:R-BTA-917977",
"REACTOME:R-BTA-9639288",
"REACTOME:R-BTA-983712",
"REACTOME:R-CEL-1222556",
"REACTOME:R-CEL-77387",
"REACTOME:R-CEL-917977",
"REACTOME:R-CEL-9639288",
"REACTOME:R-CEL-983712",
"REACTOME:R-DDI-1222556",
"REACTOME:R-DDI-... | 42 | [
"3j9t",
"3j9u",
"3j9v",
"4ix9",
"4rnd",
"5d80",
"5vox",
"5voy",
"5voz",
"6o7v",
"6o7w",
"6o7x",
"6vq6",
"6vq7",
"6vq8",
"6vqc",
"6vqg",
"6vqh",
"6wlz",
"6wm2",
"6wm3",
"6wm4",
"6xbw",
"6xby",
"7fda",
"7fdb",
"7fdc",
"7fde",
"7khr",
"7tmm",
"7tmo",
"7tmp"... | 69 | [
"PUB00020603",
"PUB00020604",
"PUB00020608",
"PUB00020609",
"PUB00020639",
"PUB00068786",
"PUB00068787",
"PUB00068788",
"PUB00068789"
] | [
"15473999",
"15078220",
"15907459",
"15629643",
"14963028",
"20450191",
"18937357",
"1385979",
"9741106"
] | [
"The evolution of A-, F-, and V-type ATP synthases and ATPases: reversals in function and changes in the H+/ATP coupling ratio.",
"Mechanisms of ATPases--a multi-disciplinary approach.",
"A new view of an old pore.",
"A structural model of the vacuolar ATPase from transmission electron microscopy.",
"The F ... | [
2004,
2004,
2005,
2005,
2004,
2010,
2008,
1992,
1998
] | 9 | [
"IPR008218"
] | [] | 1 | 0 | 1 | [
"Eukaryota",
"Salinarimonas soli",
"bird metagenome"
] | [
4115,
1,
1
] | 3 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
2,
1,
1,
4,
2,
3,
1,
3,
5,
1,
1,
7
] | 12 | true | Family | ATPase, V1 complex, subunit F, eukaryotic | ATPase, V1 complex, subunit F, eukaryotic | ATPase_V1-cplx_fsu_euk | 2 |
IPR005773 | 5,773 | Type III secretion system, Yop virulence translocation protein R-like | T3SS_YscR-like | Family | 3,208 | false | false | This entry represents a group of virulence translocation proteins mainly found in the type III secretion system in proteobacteria, including Yop proteins translocation protein R from Yersinia pestis (YscR) and Surface presentation of antigens protein SpaP from Salmonella typhimurium. YscR is a component of the yop secr... | [
"GO:0015031",
"GO:0016020"
] | [
"protein transport",
"membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01102"
] | [
"yscR"
] | [
3208
] | 1 | [
"GP"
] | [
"GenProp0052"
] | [
"GP:GenProp0052"
] | 1 | [
"6pem",
"6pep",
"6q14",
"6q15",
"6q16",
"6r6b",
"6rwy",
"7agx",
"7ah9",
"7ahi",
"8axk"
] | 11 | [
"PUB00106863"
] | [
"7638176"
] | [
"Relationship between evolutionary rate and cellular location among the Inv/Spa invasion proteins of Salmonella enterica."
] | [
1995
] | 1 | [
"IPR005838"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
3198,
3,
7
] | 3 | [
"Zea mays"
] | [
1
] | 1 | true | Family | Type III secretion system, Yop virulence translocation protein R-like | Type III secretion system, Yop virulence translocation protein R-like | T3SS_YscR-like | 9 |
IPR005774 | 5,774 | UTP-glucose pyrophosphorylase, regulatory subunit | GalF | Family | 906 | false | false | This family of proteins, GalF, represents a non-catalytic subunit of the UTP-glucose pyrophosphorylase modulating the enzyme activity to increase the formation of UDP-glucose [ ]. | [
"GO:0030234",
"GO:0006011"
] | [
"enzyme regulator activity",
"UDP-alpha-D-glucose metabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01105"
] | [
"galF"
] | [
906
] | 1 | [
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"
] | [
"2.7.7.9",
"PWY-3801",
"PWY-6527",
"PWY-7238",
"PWY-7343",
"PWY-7817"
] | [
"EC:2.7.7.9",
"METACYC:PWY-3801",
"METACYC:PWY-6527",
"METACYC:PWY-7238",
"METACYC:PWY-7343",
"METACYC:PWY-7817"
] | 6 | [] | 0 | [
"PUB00007892"
] | [
"8971705"
] | [
"The GalF protein of Escherichia coli is not a UDP-glucose pyrophosphorylase but interacts with the GalU protein possibly to regulate cellular levels of UDP-glucose."
] | [
1996
] | 1 | [] | [] | 0 | 0 | null | [
"Gammaproteobacteria",
"human gut metagenome"
] | [
905,
1
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | UTP-glucose pyrophosphorylase, regulatory subunit | UTP-glucose pyrophosphorylase, regulatory subunit | GalF | 9 |
IPR005776 | 5,776 | Oxaloacetate decarboxylase, alpha subunit | OadA | Family | 5,637 | false | false | This family describes the bacterial oxaloacetate decarboxylase alpha subunit and its equivalents in archaea [ ]. The oxaloacetate decarboxylase Na+ pump is the paradigm of the family of Na+ transport decarboxylases that present in bacteria and archaea. It a multi subunit enzyme consisting of a peripheral alpha-subunit ... | [
"GO:0008948",
"GO:0006814"
] | [
"oxaloacetate decarboxylase activity",
"sodium ion transport"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01108"
] | [
"oadA"
] | [
5637
] | 1 | [
"EC"
] | [
"7.2.4.2"
] | [
"EC:7.2.4.2"
] | 1 | [
"2nx9",
"5ks8"
] | 2 | [
"PUB00007893"
] | [
"11248185"
] | [
"Sodium ion-translocating decarboxylases."
] | [
2001
] | 1 | [
"IPR055268"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Symbiodinium",
"ecological metagenomes"
] | [
211,
5371,
2,
53
] | 4 | [] | [] | 0 | true | Family | Oxaloacetate decarboxylase, alpha subunit | Oxaloacetate decarboxylase, alpha subunit | OadA | 9 |
IPR005777 | 5,777 | Acetyl-S-ACP:malonate ACP transferase | MadA | Family | 2,877 | false | false | MadA is an alpha subunit of the biotin-dependent and biotin-independent malonate decarboxylase multienzyme complex (( ) and ( )). It acts as an acyl-carrier protein (ACP) transferase component. This first step in malonate decarboxylation involves the exchange of an acetyl thioester residue bound to the activated ACP su... | [
"GO:0016740"
] | [
"transferase activity"
] | [
"molecular_function"
] | 1 | [
"PFAM",
"NCBIFAM"
] | [
"PF16957",
"TIGR01110"
] | [
"Mal_decarbox_Al",
"mdcA"
] | [
2877,
2722
] | 2 | [
"GP"
] | [
"GenProp0674"
] | [
"GP:GenProp0674"
] | 1 | [
"5vit",
"5vj1",
"6mpr"
] | 3 | [
"PUB00075947"
] | [
"18251085"
] | [
"Purification and characterization of a cytoplasmic enzyme component of the Na+-activated malonate decarboxylase system of Malonomonas rubra: acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase."
] | [
1994
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Methanofastidiosum methylothiophilum",
"Opisthokonta",
"metagenomes"
] | [
2861,
3,
4,
9
] | 4 | [] | [] | 0 | true | Family | Acetyl-S-ACP:malonate ACP transferase | Acetyl-S-ACP:malonate ACP transferase | MadA | 8 |
IPR005778 | 5,778 | Tetrahydromethanopterin S-methyltransferase subunit A, MtrA | MtrA | Family | 335 | false | false | Tetrahydromethanopterin S-methyltransferase is a complex that catalyses the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin in methanogenic archaea [ ]. It is a membrane-associated enzyme complex that uses the methyl-transfer reaction to drive a sodium-ion p... | [
"GO:0030269",
"GO:0050897",
"GO:0006814"
] | [
"tetrahydromethanopterin S-methyltransferase activity",
"cobalt ion binding",
"sodium ion transport"
] | [
"molecular_function",
"molecular_function",
"biological_process"
] | 3 | [
"HAMAP",
"PIRSF",
"NCBIFAM"
] | [
"MF_01093",
"PIRSF500207",
"TIGR01111"
] | [
"MtrA",
"MtrA",
"mtrA"
] | [
314,
331,
323
] | 3 | [
"EC",
"GP",
"GP"
] | [
"7.2.1.4",
"GenProp0288",
"GenProp0722"
] | [
"EC:7.2.1.4",
"GP:GenProp0288",
"GP:GenProp0722"
] | 3 | [
"5l8x",
"5laa",
"8q3v",
"8q54"
] | 4 | [
"PUB00009902",
"PUB00056777",
"PUB00056778"
] | [
"9559648",
"8477726",
"8898900"
] | [
"Cloning, sequencing and expression of the genes encoding the sodium translocating N5-methyltetrahydromethanopterin : coenzyme M methyltransferase of the methylotrophic archaeon Methanosarcina mazei Go1.",
"Purification and properties of N5-methyltetrahydromethanopterin:coenzyme M methyltransferase from Methanoba... | [
1998,
1993,
1996
] | 3 | [
"IPR030688"
] | [] | 1 | 0 | 1 | [
"Archaea",
"ecological metagenomes"
] | [
329,
6
] | 2 | [] | [] | 0 | true | Family | Tetrahydromethanopterin S-methyltransferase subunit A, MtrA | Tetrahydromethanopterin S-methyltransferase subunit A, MtrA | MtrA | 9 |
IPR005779 | 5,779 | Tetrahydromethanopterin S-methyltransferase, subunit D | MeTrfase_D | Family | 231 | false | false | This model describes N5-methyltetrahydromethanopterin: coenzyme M methyltransferase subunit D in methanogenic archaea. This methyltranferase is a membrane-associated enzyme complex that uses methyl-transfer reaction to drive sodium-ion pump. 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulphonate = 5,6,7,... | [
"GO:0030269",
"GO:0006814",
"GO:0005737",
"GO:0012506"
] | [
"tetrahydromethanopterin S-methyltransferase activity",
"sodium ion transport",
"cytoplasm",
"vesicle membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component",
"cellular_component"
] | 4 | [
"HAMAP",
"PFAM",
"PIRSF",
"NCBIFAM"
] | [
"MF_01097",
"PF04207",
"PIRSF016552",
"TIGR01112"
] | [
"MtrD",
"MtrD",
"MtrD",
"mtrD"
] | [
220,
231,
209,
231
] | 4 | [
"EC",
"GP",
"GP"
] | [
"7.2.1.4",
"GenProp0288",
"GenProp0722"
] | [
"EC:7.2.1.4",
"GP:GenProp0288",
"GP:GenProp0722"
] | 3 | [
"8q3v",
"8q54"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"ecological metagenomes"
] | [
226,
5
] | 2 | [] | [] | 0 | true | Family | Tetrahydromethanopterin S-methyltransferase, subunit D | Tetrahydromethanopterin S-methyltransferase, subunit D | MeTrfase_D | 1 |
IPR005780 | 5,780 | Tetrahydromethanopterin S-methyltransferase, subunit E | MeTrfase_E | Family | 231 | false | false | This model describes N5-methyltetrahydromethanopterin: coenzyme M methyltransferase subunit E in methanogenic archaea. This methyltranferase is a membrane-associated enzyme complex that uses methyl-transfer reaction to drive sodium-ion pump. 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulphonate = 5,6,7,... | [
"GO:0030269",
"GO:0006814",
"GO:0005737",
"GO:0012506"
] | [
"tetrahydromethanopterin S-methyltransferase activity",
"sodium ion transport",
"cytoplasm",
"vesicle membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component",
"cellular_component"
] | 4 | [
"HAMAP",
"PFAM",
"PIRSF",
"NCBIFAM"
] | [
"MF_01098",
"PF04206",
"PIRSF016509",
"TIGR01113"
] | [
"MtrE",
"MtrE",
"MtrE",
"mtrE"
] | [
220,
231,
221,
227
] | 4 | [
"EC",
"GP",
"GP"
] | [
"7.2.1.4",
"GenProp0288",
"GenProp0722"
] | [
"EC:7.2.1.4",
"GP:GenProp0288",
"GP:GenProp0722"
] | 3 | [
"8q3v",
"8q54"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"ecological metagenomes"
] | [
226,
5
] | 2 | [] | [] | 0 | true | Family | Tetrahydromethanopterin S-methyltransferase, subunit E | Tetrahydromethanopterin S-methyltransferase, subunit E | MeTrfase_E | 4 |
IPR005781 | 5,781 | Photosynthetic reaction centre, M subunit | Photo_RC_M | Family | 975 | false | false | This entry describes the photosynthetic reaction centre M subunit. The L and M subunits are arranged around an axis of 2-fold rotational symmetry perpendicular to the membrane, forming a scaffold that maintains the cofactors in a precise configuration. The L and M subunits have both sequence and structural similarity, ... | [
"GO:0019684",
"GO:0030077"
] | [
"photosynthesis, light reaction",
"plasma membrane light-harvesting complex"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"NCBIFAM",
"CDD"
] | [
"TIGR01115",
"cd09291"
] | [
"pufM",
"Photo-RC_M"
] | [
975,
350
] | 2 | [
"GP"
] | [
"GenProp0662"
] | [
"GP:GenProp0662"
] | 1 | [
"1aig",
"1aij",
"1ds8",
"1dv3",
"1dv6",
"1dxr",
"1e14",
"1e6d",
"1eys",
"1f6n",
"1fnp",
"1fnq",
"1jgw",
"1jgx",
"1jgy",
"1jgz",
"1jh0",
"1k6l",
"1k6n",
"1kby",
"1l9b",
"1l9j",
"1m3x",
"1mps",
"1ogv",
"1pcr",
"1prc",
"1pss",
"1pst",
"1qov",
"1r2c",
"1rg5"... | 220 | [
"PUB00014111",
"PUB00014116",
"PUB00015279",
"PUB00015395",
"PUB00034760",
"PUB00034761",
"PUB00034762"
] | [
"11095707",
"11005826",
"2676514",
"12872158",
"15329728",
"16931113",
"8027023"
] | [
"Crystal structures of photosynthetic reaction center and high-potential iron-sulfur protein from Thermochromatium tepidum: thermostability and electron transfer.",
"Structural basis of the drastically increased initial electron transfer rate in the reaction center from a Rhodopseudomonas viridis mutant described... | [
2000,
2000,
1989,
2003,
2004,
2006,
1994
] | 7 | [
"IPR000484"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Effrenium voratum",
"freshwater sediment metagenome"
] | [
973,
1,
1
] | 3 | [] | [] | 0 | true | Family | Photosynthetic reaction centre, M subunit | Photosynthetic reaction centre, M subunit | Photo_RC_M | 6 |
IPR005782 | 5,782 | P-type ATPase, subfamily IIA, SERCA-type | P-type_ATPase_IIA | Family | 10,522 | false | false | This entry represents the P-type ATPase responsible for translocating calcium ions across the endoplasmic reticulum membrane of eukaryotes [ ], and is of particular importance in the sarcoplasmic reticulum of skeletal and cardiac muscle in vertebrates [ ]. These pumps transfer Ca2+ from the cytoplasm to the lumen of th... | [
"GO:0005388",
"GO:0006816",
"GO:0016020"
] | [
"P-type calcium transporter activity",
"calcium ion transport",
"membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"NCBIFAM"
] | [
"TIGR01116"
] | [
"ATPase-IIA1_Ca"
] | [
10522
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"7.2.2.10",
"R-BTA-418359",
"R-BTA-5578775",
"R-BTA-936837",
"R-CFA-418359",
"R-CFA-5578775",
"R-CFA-936837",
"R-DME-418359",
"R-DME-5578775",
"R-DME-936837",
"R-HSA-1912420",
"R-HSA-418359",
"R-HSA-5578775",
"R-HSA-936837",
"R-MMU-418359",
"R-MMU-5578775",
"R-MMU-936837",
"R-RNO-4... | [
"EC:7.2.2.10",
"REACTOME:R-BTA-418359",
"REACTOME:R-BTA-5578775",
"REACTOME:R-BTA-936837",
"REACTOME:R-CFA-418359",
"REACTOME:R-CFA-5578775",
"REACTOME:R-CFA-936837",
"REACTOME:R-DME-418359",
"REACTOME:R-DME-5578775",
"REACTOME:R-DME-936837",
"REACTOME:R-HSA-1912420",
"REACTOME:R-HSA-418359",
... | 23 | [
"1iwo",
"1kju",
"1su4",
"1t5s",
"1t5t",
"1vfp",
"1wpg",
"1xp5",
"2agv",
"2by4",
"2c88",
"2c8k",
"2c8l",
"2c9m",
"2dqs",
"2ear",
"2eat",
"2eau",
"2o9j",
"2oa0",
"2yfy",
"2zbd",
"2zbe",
"2zbf",
"2zbg",
"3ar2",
"3ar3",
"3ar4",
"3ar5",
"3ar6",
"3ar7",
"3ar8"... | 96 | [
"PUB00009616",
"PUB00009622",
"PUB00017632",
"PUB00017633",
"PUB00017634",
"PUB00020603",
"PUB00020604",
"PUB00068786",
"PUB00068787",
"PUB00068788",
"PUB00068789",
"PUB00160065",
"PUB00160066"
] | [
"9419228",
"10433975",
"11302372",
"11444913",
"10951187",
"15473999",
"15078220",
"20450191",
"18937357",
"1385979",
"9741106",
"37264943",
"37838176"
] | [
"Evolution of substrate specificities in the P-type ATPase superfamily.",
"Two additional type IIA Ca(2+)-ATPases are expressed in Arabidopsis thaliana: evidence that type IIA sub-groups exist.",
"Sarco(endo)plasmic reticulum calcium pumps: recent advances in our understanding of structure/function and biology ... | [
1998,
1999,
2000,
2001,
2000,
2004,
2004,
2010,
2008,
1992,
1998,
2023,
2023
] | 13 | [
"IPR001757"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"ecological metagenomes"
] | [
36,
1474,
9007,
5
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
5,
3,
13,
3,
9,
10,
1,
3,
19,
1
] | 10 | true | Family | P-type ATPase, subfamily IIA, SERCA-type | P-type ATPase, subfamily IIA, SERCA-type | P-type_ATPase_IIA | 6 |
IPR005783 | 5,783 | Methylmalonyl-CoA decarboxylase, alpha subunit | MemalonylCoA_decase_suA | Family | 17 | false | false | This family describes methymalonyl-CoA decarboxylase alpha subunit ( ) in archaea and bacteria. Metylmalonyl-CoA decarboxylase Na+ pump is a representative of a class of Na transport decarboxylases that couples the energy derived by decarboxylation of carboxylic acid substrates to drive the extrusion of Na+ ion across ... | [] | [] | [] | 0 | [
"NCBIFAM"
] | [
"TIGR01117"
] | [
"mmdA"
] | [
17
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00016214"
] | [
"9428714"
] | [
"Methylmalonyl-CoA decarboxylase from Propionigenium modestum--cloning and sequencing of the structural genes and purification of the enzyme complex."
] | [
1997
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanobacteriota"
] | [
5,
12
] | 2 | [] | [] | 0 | true | Family | Methylmalonyl-CoA decarboxylase, alpha subunit | Methylmalonyl-CoA decarboxylase, alpha subunit | MemalonylCoA_decase_suA | 7 |
IPR005784 | 5,784 | D-amino acid aminotransferase | D_amino_transT | Family | 1,945 | false | false | D-amino acid aminotransferase ( ) catalyzes transamination between various D-amino acids and alpha-keto acids. This enzyme is a homodimer. The pyridoxal phosphate attachment site is a Lys in the motif Cys-Asp-Ile-Lys-Ser-Leu-Asn. Specificity is broad for various D-amino acids, and differs among members of the family [ ... | [
"GO:0008483",
"GO:0030170",
"GO:0046416"
] | [
"transaminase activity",
"pyridoxal phosphate binding",
"D-amino acid metabolic process"
] | [
"molecular_function",
"molecular_function",
"biological_process"
] | 3 | [
"NCBIFAM"
] | [
"TIGR01121"
] | [
"D_amino_aminoT"
] | [
1945
] | 1 | [
"EC",
"METACYC"
] | [
"2.6.1.21",
"PWY-8448"
] | [
"EC:2.6.1.21",
"METACYC:PWY-8448"
] | 2 | [
"1a0g",
"1daa",
"1g2w",
"2daa",
"2dab",
"3daa",
"3lqs",
"4daa",
"5daa"
] | 9 | [
"PUB00007894"
] | [
"2914916"
] | [
"Thermostable D-amino acid aminotransferase from a thermophilic Bacillus species. Purification, characterization, and active site sequence determination."
] | [
1989
] | 1 | [
"IPR001544"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Hydra vulgaris",
"metagenomes"
] | [
1939,
1,
5
] | 3 | [] | [] | 0 | true | Family | D-amino acid aminotransferase | D-amino acid aminotransferase | D_amino_transT | 5 |
IPR005785 | 5,785 | Branched-chain amino acid aminotransferase I | B_amino_transI | Family | 11,529 | false | false | Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped [ ] into subfamilies. One of these, called class-IV, current... | [
"GO:0004084",
"GO:0009081"
] | [
"branched-chain-amino-acid transaminase activity",
"branched-chain amino acid metabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01122"
] | [
"ilvE_I"
] | [
11529
] | 1 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC"
] | [
"2.6.1.42",
"GenProp0162",
"GenProp0163",
"GenProp0164",
"GenProp1533",
"GenProp1667",
"GenProp1673",
"GenProp1708",
"PWY-5057",
"PWY-5076",
"PWY-5078",
"PWY-5101",
"PWY-5103",
"PWY-5104",
"PWY-5108",
"PWY-7767",
"PWY-8173",
"PWY-8174",
"PWY-8175",
"PWY-8183",
"PWY-8184",
"... | [
"EC:2.6.1.42",
"GP:GenProp0162",
"GP:GenProp0163",
"GP:GenProp0164",
"GP:GenProp1533",
"GP:GenProp1667",
"GP:GenProp1673",
"GP:GenProp1708",
"METACYC:PWY-5057",
"METACYC:PWY-5076",
"METACYC:PWY-5078",
"METACYC:PWY-5101",
"METACYC:PWY-5103",
"METACYC:PWY-5104",
"METACYC:PWY-5108",
"META... | 22 | [
"1a3g",
"1i1k",
"1i1l",
"1i1m",
"1iyd",
"1iye",
"1wrv",
"2eiy",
"2ej0",
"2ej2",
"2ej3",
"3u0g",
"4whx",
"5ce8",
"5cm0",
"5e25",
"5mqz",
"5mr0",
"6gkr",
"6h65",
"6nst",
"6q8e",
"6thq",
"7nea",
"7neb"
] | 25 | [
"PUB00002195"
] | [
"1644759"
] | [
"Characterization and sequence of Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme."
] | [
1992
] | 1 | [
"IPR033939"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
791,
10421,
35,
282
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Branched-chain amino acid aminotransferase I | Branched-chain amino acid aminotransferase I | B_amino_transI | 6 |
IPR005786 | 5,786 | Branched-chain amino acid aminotransferase II | B_amino_transII | Family | 28,736 | false | false | Aminotransferases share certain mechanistic features with other pyridoxal-phosphate dependent enzymes, such as the covalent binding of the pyridoxal-phosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped [ ] into subfamilies. One of these, called class-IV, current... | [
"GO:0004084",
"GO:0009081"
] | [
"branched-chain-amino-acid transaminase activity",
"branched-chain amino acid metabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PIRSF",
"PANTHER",
"PANTHER",
"NCBIFAM"
] | [
"PIRSF006468",
"PTHR11825",
"PTHR42825",
"TIGR01123"
] | [
"BCAT1",
"",
"",
"ilvE_II"
] | [
25753,
19203,
9481,
23483
] | 4 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"2.6.1.42",
"GenProp0162",
"GenProp0163",
"GenProp0164",
"GenProp1328",
"GenProp1334",
"GenProp1467",
"PWY-5057",
"PWY-5076",
"PWY-5078",
"PWY-5101",
"PWY-5103",
"PWY-5104",
"PWY-5108",
"PWY-7767",
"PWY-8173",
"PWY-8174",
"PWY-8175",
"PWY-8183",
"PWY-8184",
"PWY-8185",
"R-B... | [
"EC:2.6.1.42",
"GP:GenProp0162",
"GP:GenProp0163",
"GP:GenProp0164",
"GP:GenProp1328",
"GP:GenProp1334",
"GP:GenProp1467",
"METACYC:PWY-5057",
"METACYC:PWY-5076",
"METACYC:PWY-5078",
"METACYC:PWY-5101",
"METACYC:PWY-5103",
"METACYC:PWY-5104",
"METACYC:PWY-5108",
"METACYC:PWY-7767",
"ME... | 29 | [
"1ekf",
"1ekp",
"1ekv",
"1kt8",
"1kta",
"2a1h",
"2abj",
"2cog",
"2coi",
"2coj",
"2hdk",
"2hg8",
"2hgw",
"2hgx",
"2hhf",
"3dtf",
"3dtg",
"3ht5",
"3jz6",
"3uyy",
"3uzb",
"3uzo",
"4dqn",
"5bwr",
"5bwt",
"5bwu",
"5bwv",
"5bww",
"5bwx",
"5cr5",
"5hne",
"5i5s"... | 57 | [
"PUB00002195",
"PUB00089640",
"PUB00089814",
"PUB00094557"
] | [
"1644759",
"27705900",
"17990954",
"30395461"
] | [
"Characterization and sequence of Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme.",
"Structural diversity in echinocandin biosynthesis: the impact of oxidation steps and approaches toward an evolutionary explanation.",
"Expression profiles of genes e... | [
1992,
2017,
2007,
2018
] | 4 | [
"IPR033939"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified Caudoviricetes",
"unclassified sequences"
] | [
28,
15163,
13235,
2,
308
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
45,
2,
15,
1,
10,
17,
3,
20,
19,
2,
1,
34
] | 12 | true | Family | Branched-chain amino acid aminotransferase II | Branched-chain amino acid aminotransferase II | B_amino_transII | 4 |
IPR005787 | 5,787 | Threonine dehydratase, biosynthetic | Thr_deHydtase_biosynth | Family | 10,383 | false | false | Threonine dehydratase ( ) (TDH) catalyzes the dehydratation of threonine into alpha-ketobutarate and ammonia. In Escherichia coli and other microorganisms, two classes of TDH are known to exist. One is involved in the biosynthesis of isoleucine, the other in hydroxamino acid catabolism. This entry describes a form of t... | [
"GO:0004794",
"GO:0009097"
] | [
"threonine deaminase activity",
"isoleucine biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01124"
] | [
"ilvA_2Cterm"
] | [
10383
] | 1 | [
"EC",
"GP",
"METACYC"
] | [
"4.3.1.19",
"GenProp0162",
"PWY-8443"
] | [
"EC:4.3.1.19",
"GP:GenProp0162",
"METACYC:PWY-8443"
] | 3 | [
"1tdj",
"3iau",
"8y1j",
"8zkv",
"9d2q",
"9jfi"
] | 6 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified Klosneuvirinae",
"unclassified sequences"
] | [
7476,
2825,
3,
79
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
3,
1,
2,
5,
1,
1,
10
] | 7 | true | Family | Threonine dehydratase, biosynthetic | Threonine dehydratase, biosynthetic | Thr_deHydtase_biosynth | 7 |
IPR005788 | 5,788 | Protein disulfide-isomerase, thioredoxin-like domain | PDI_thioredoxin-like_dom | Domain | 17,815 | false | false | This entry represents a domain found in eukaryotic protein disulphide isomerases (PDI), multifunctional proteins that catalyse the formation, breakage and rearrangement of disulfide bonds [ , , , ]. PDI generally shows four thioredoxin-like domains. This entry represents the two redox active domains, which are located ... | [
"GO:0003756"
] | [
"protein disulfide isomerase activity"
] | [
"molecular_function"
] | 1 | [
"NCBIFAM"
] | [
"TIGR01126"
] | [
"pdi_dom"
] | [
17815
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
... | [
"5.3.4.1",
"R-CEL-1650814",
"R-CEL-264876",
"R-CEL-381426",
"R-CEL-8957275",
"R-CEL-8964041",
"R-DDI-901042",
"R-DME-1650814",
"R-DME-264876",
"R-DME-381426",
"R-DME-432720",
"R-DME-5358346",
"R-DME-6798695",
"R-DME-8957275",
"R-DME-8964041",
"R-GGA-1236974",
"R-GGA-901042",
"R-GGA... | [
"EC:5.3.4.1",
"REACTOME:R-CEL-1650814",
"REACTOME:R-CEL-264876",
"REACTOME:R-CEL-381426",
"REACTOME:R-CEL-8957275",
"REACTOME:R-CEL-8964041",
"REACTOME:R-DDI-901042",
"REACTOME:R-DME-1650814",
"REACTOME:R-DME-264876",
"REACTOME:R-DME-381426",
"REACTOME:R-DME-432720",
"REACTOME:R-DME-5358346",
... | 68 | [
"1mek",
"1x5c",
"1x5d",
"2alb",
"2diz",
"2dj1",
"2dj2",
"2dj3",
"2djj",
"2dml",
"2dmm",
"2kp1",
"2rue",
"2ruf",
"3f8u",
"3idv",
"3uem",
"3uj1",
"3uvt",
"3vww",
"3w8j",
"3wge",
"3wgx",
"3wt1",
"3wt2",
"4ef0",
"4ekz",
"4el1",
"4gwr",
"5crw",
"6eny",
"6i7s"... | 39 | [
"PUB00002883",
"PUB00051906",
"PUB00103863",
"PUB00103864",
"PUB00103865",
"PUB00103866"
] | [
"7983029",
"19119025",
"27897272",
"25697778",
"32149426",
"21670307"
] | [
"Mutations in the thioredoxin sites of protein disulfide isomerase reveal functional nonequivalence of the N- and C-terminal domains.",
"Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer.",
"Analysis of the interaction of calcitriol with the disul... | [
1994,
2009,
2016,
2015,
2020,
2011
] | 6 | [
"IPR013766"
] | [] | 1 | 0 | 1 | [
"Eukaryota",
"Gammaproteobacteria"
] | [
17811,
4
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Schizosaccharomyces pombe (stra... | [
27,
6,
13,
7,
62,
32,
2,
12,
25,
2,
70
] | 11 | true | Domain | Protein disulfide-isomerase, thioredoxin-like domain | Protein disulfide-isomerase, thioredoxin-like domain | PDI_thioredoxin-like_dom | 8 |
IPR005789 | 5,789 | Threonine dehydratase, catabolic | Thr_deHydtase_catblc | Family | 9,750 | false | false | Threonine dehydratase ( ) (TDH) catalyzes the dehydratation of threonine into alpha-ketobutarate and ammonia. In Escherichia coli and other microorganisms, two classes of TDH are known to exist. One is involved in the biosynthesis of isoleucine, the other in hydroxamino acid catabolism. A form of TDH with two copies of... | [
"GO:0004794",
"GO:0006567"
] | [
"threonine deaminase activity",
"L-threonine catabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01127"
] | [
"ilvA_1Cterm"
] | [
9750
] | 1 | [
"EC",
"GP",
"METACYC"
] | [
"4.3.1.19",
"GenProp0162",
"PWY-8443"
] | [
"EC:4.3.1.19",
"GP:GenProp0162",
"METACYC:PWY-8443"
] | 3 | [
"2gn0",
"2gn1",
"2gn2"
] | 3 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
847,
8497,
306,
100
] | 4 | [
"Caenorhabditis elegans",
"Escherichia coli (strain K12)"
] | [
1,
1
] | 2 | true | Family | Threonine dehydratase, catabolic | Threonine dehydratase, catabolic | Thr_deHydtase_catblc | 6 |
IPR005790 | 5,790 | DNA polymerase III, delta subunit | DNA_polIII_delta | Family | 28,650 | false | false | This family of proteins includes subunits of DNA polymerase III, specifically the delta subunit, which plays a crucial role in bacterial DNA replication. The delta subunit is involved in the assembly of the DNA polymerase III holoenzyme by interacting with other subunits to facilitate the loading of the beta sliding cl... | [
"GO:0003677",
"GO:0006260"
] | [
"DNA binding",
"DNA replication"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PANTHER",
"NCBIFAM"
] | [
"PTHR34388",
"TIGR01128"
] | [
"",
"holA"
] | [
26451,
27847
] | 2 | [
"EC",
"GP"
] | [
"2.7.7.7",
"GenProp0263"
] | [
"EC:2.7.7.7",
"GP:GenProp0263"
] | 2 | [
"1jqj",
"1jql",
"1jr3",
"1xxh",
"1xxi",
"3glf",
"3glg",
"3glh",
"3gli",
"3zh9",
"8giy",
"8giz",
"8gj0",
"8gj1",
"8gj2",
"8gj3",
"8val",
"8vam",
"8van",
"8vap",
"8vaq",
"8var",
"8vas",
"8vat"
] | 24 | [
"PUB00007895",
"PUB00026496"
] | [
"8505304",
"11525728"
] | [
"DNA polymerase III accessory proteins. II. Characterization of delta and delta'.",
"Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III."
] | [
1993,
2001
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified Caudoviricetes",
"unclassified sequences"
] | [
27966,
36,
6,
642
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | DNA polymerase III, delta subunit | DNA polymerase III, delta subunit | DNA_polIII_delta | 3 |
IPR005791 | 5,791 | Protein translocase subunit SecD | SecD | Family | 25,886 | false | false | Secretion across the inner membrane in some Gram-negative bacteria occurs via the preprotein translocase pathway. Proteins are produced in the cytoplasm as precursors, and require a chaperone subunit to direct them to the translocase component [ ]. From there, the mature proteins are either targeted to the outer membra... | [
"GO:0015450",
"GO:0006886"
] | [
"protein-transporting ATPase activity",
"intracellular protein transport"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_01463_B",
"TIGR01129"
] | [
"SecD_B",
"secD"
] | [
25657,
25748
] | 2 | [
"GP",
"GP",
"REACTOME"
] | [
"GenProp0209",
"GenProp1132",
"R-HSA-1222387"
] | [
"GP:GenProp0209",
"GP:GenProp1132",
"REACTOME:R-HSA-1222387"
] | 3 | [
"3aqp",
"5mg3",
"5xam",
"5xan",
"5xap",
"5yhf"
] | 6 | [
"PUB00007064",
"PUB00007065",
"PUB00007066",
"PUB00007187",
"PUB00059727"
] | [
"2202721",
"11336818",
"10418149",
"12167867",
"21562494"
] | [
"The sec and prl genes of Escherichia coli.",
"SecB, a molecular chaperone with two faces.",
"Effects of pre-protein overexpression on SecB synthesis in Escherichia coli.",
"Three-dimensional structure of the bacterial protein-translocation complex SecYEG.",
"Structure and function of a membrane component S... | [
1990,
2001,
1999,
2002,
2011
] | 5 | [
"IPR022645"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"Siphoviridae sp. ctJ0s2",
"unclassified sequences"
] | [
25338,
53,
1,
494
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein translocase subunit SecD | Protein translocase subunit SecD | SecD | 4 |
IPR005792 | 5,792 | Protein disulphide isomerase | Prot_disulphide_isomerase | Family | 10,026 | false | false | This family represents eukaryotic protein disulphide isomerases retained in the endoplasmic reticulum (ER) and other closely related forms [ ]. Some members have been assigned alternative or additional functions such as prolyl 4-hydroxylase [ , ]. Members of this family have at least two protein-disulphide domains, eac... | [
"GO:0003756"
] | [
"protein disulfide isomerase activity"
] | [
"molecular_function"
] | 1 | [
"NCBIFAM"
] | [
"TIGR01130"
] | [
"ER_PDI_fam"
] | [
10026
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
... | [
"5.3.4.1",
"R-CEL-1650814",
"R-CEL-264876",
"R-CEL-381426",
"R-CEL-8957275",
"R-CEL-8964041",
"R-DDI-901042",
"R-DME-1650814",
"R-DME-264876",
"R-DME-381426",
"R-DME-5358346",
"R-DME-8957275",
"R-DME-8964041",
"R-GGA-1236974",
"R-GGA-901042",
"R-GGA-983170",
"R-HSA-1236974",
"R-HSA... | [
"EC:5.3.4.1",
"REACTOME:R-CEL-1650814",
"REACTOME:R-CEL-264876",
"REACTOME:R-CEL-381426",
"REACTOME:R-CEL-8957275",
"REACTOME:R-CEL-8964041",
"REACTOME:R-DDI-901042",
"REACTOME:R-DME-1650814",
"REACTOME:R-DME-264876",
"REACTOME:R-DME-381426",
"REACTOME:R-DME-5358346",
"REACTOME:R-DME-8957275",... | 61 | [
"2b5e",
"3boa",
"3f8u",
"4ekz",
"4el1",
"6eny",
"6i7s",
"7qng",
"7qpd",
"7zsc",
"8eoj",
"8pko",
"8zpw"
] | 13 | [
"PUB00089633",
"PUB00089642",
"PUB00089643"
] | [
"12384992",
"10597631",
"2846539"
] | [
"Proteins of the PDI family: unpredicted non-ER locations and functions.",
"Protein disulfide isomerase: the multifunctional redox chaperone of the endoplasmic reticulum.",
"Characterization of the human gene for a polypeptide that acts both as the beta subunit of prolyl 4-hydroxylase and as protein disulfide i... | [
2002,
1999,
1988
] | 3 | [] | [
"IPR017068"
] | 0 | 1 | 0 | [
"Eukaryota",
"Gammaproteobacteria"
] | [
10022,
4
] | 2 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
14,
4,
9,
5,
33,
17,
1,
8,
10,
2,
1,
32
] | 12 | true | Family | Protein disulphide isomerase | Protein disulphide isomerase | Prot_disulphide_isomerase | 3 |
IPR005793 | 5,793 | Formyl transferase, C-terminal | Formyl_trans_C | Domain | 40,123 | false | false | Methionyl-tRNA formyltransferase ( ) transfers a formyl group onto the amino terminus of the acyl moiety of the methionyl aminoacyl-tRNA. The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and by impairing its binding to EFTU-GTP. This fa... | [
"GO:0009058"
] | [
"biosynthetic process"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF02911"
] | [
"Formyl_trans_C"
] | [
40123
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.1.2.9",
"R-HSA-196757",
"R-HSA-5368286",
"R-MMU-196757",
"R-RNO-196757",
"R-XTR-196757"
] | [
"EC:2.1.2.9",
"REACTOME:R-HSA-196757",
"REACTOME:R-HSA-5368286",
"REACTOME:R-MMU-196757",
"REACTOME:R-RNO-196757",
"REACTOME:R-XTR-196757"
] | 6 | [
"1fmt",
"1s3i",
"1yrw",
"1z7e",
"2bln",
"2bw0",
"2cfi",
"2fmt",
"3q0i",
"3r8x",
"3tqq",
"4iqf",
"4qpc",
"4qpd",
"4r8v",
"4ts4",
"4tt8",
"4tts",
"4wkg",
"5j63",
"5uai",
"6j0p",
"6j1e",
"6j1f",
"6j1g",
"6j1h",
"6j1i",
"6j1j",
"6pih",
"6pik",
"7rlt",
"7rlu"... | 34 | [
"PUB00014118"
] | [
"8887566"
] | [
"Structure of crystalline Escherichia coli methionyl-tRNA(f)Met formyltransferase: comparison with glycinamide ribonucleotide formyltransferase."
] | [
1996
] | 1 | [] | [
"IPR044135"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified Caudoviricetes",
"unclassified sequences"
] | [
57,
33295,
6067,
2,
702
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (s... | [
8,
1,
4,
5,
2,
12,
7,
2,
13,
1,
1,
7
] | 12 | true | Domain | Formyl transferase, C-terminal | Formyl transferase, C-terminal | Formyl_trans_C | 7 |
IPR005795 | 5,795 | Major pollen allergen Lol pI | LolPI | Family | 4,806 | false | false | Grass pollens are a major cause of type I allergy. Lol pI, the major rye grass (Lolium perenne) allergen, is a 240-amino acid protein [ ]. Analysis of the amino acid sequence has revealed a determinant within the Lol pI molecule that is recognised by human leukocyte antigen class II-restricted T cells obtained from pat... | [
"GO:0019953",
"GO:0005576"
] | [
"sexual reproduction",
"extracellular region"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PRINTS"
] | [
"PR00829"
] | [
"LOLP1ALLERGN"
] | [
4806
] | 1 | [] | [] | [] | 0 | [
"1n10",
"2hcz",
"7xc8"
] | 3 | [
"PUB00001833",
"PUB00002579"
] | [
"8406014",
"1697854"
] | [
"Zea mI, the maize homolog of the allergen-encoding Lol pI gene of rye grass.",
"cDNA cloning and immunological characterization of the rye grass allergen Lol p I."
] | [
1993,
1990
] | 2 | [
"IPR007118"
] | [] | 1 | 0 | 1 | [
"Streptomyces lavendulae subsp. lavendulae",
"Streptophytina"
] | [
1,
4805
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
38,
39,
182
] | 3 | true | Family | Major pollen allergen Lol pI | Major pollen allergen Lol pI | LolPI | 1 |
IPR005798 | 5,798 | Cytochrome b/b6, C-terminal | Cyt_b/b6_C | Domain | 245,670 | false | false | In the mitochondrion of eukaryotes and in aerobic prokaryotes, cytochrome b is a component of respiratory chain complex III ( ) - also known as the bc1 complex or ubiquinol-cytochrome c reductase. In plant chloroplasts and cyanobacteria, there is a analogous protein, cytochrome b6, a component of the plastoquinone-plas... | [
"GO:0009055",
"GO:0016491",
"GO:0016020"
] | [
"electron transfer activity",
"oxidoreductase activity",
"membrane"
] | [
"molecular_function",
"molecular_function",
"cellular_component"
] | 3 | [
"PFAM",
"PROFILE"
] | [
"PF00032",
"PS51003"
] | [
"Cytochrom_B_C",
"CYTB_CTER"
] | [
206804,
244488
] | 2 | [
"GP",
"PROSITEDOC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
... | [
"GenProp0613",
"PDOC00171",
"R-BTA-5419276",
"R-BTA-611105",
"R-BTA-9865881",
"R-CEL-5419276",
"R-CEL-611105",
"R-CEL-9865881",
"R-DDI-611105",
"R-DME-5419276",
"R-DME-611105",
"R-DME-9865881",
"R-DRE-611105",
"R-DRE-9865881",
"R-GGA-5419276",
"R-GGA-611105",
"R-GGA-9865881",
"R-HS... | [
"GP:GenProp0613",
"PROSITEDOC:PDOC00171",
"REACTOME:R-BTA-5419276",
"REACTOME:R-BTA-611105",
"REACTOME:R-BTA-9865881",
"REACTOME:R-CEL-5419276",
"REACTOME:R-CEL-611105",
"REACTOME:R-CEL-9865881",
"REACTOME:R-DDI-611105",
"REACTOME:R-DME-5419276",
"REACTOME:R-DME-611105",
"REACTOME:R-DME-986588... | 29 | [
"1bcc",
"1be3",
"1bgy",
"1ezv",
"1kb9",
"1kyo",
"1l0l",
"1l0n",
"1ntk",
"1ntm",
"1ntz",
"1nu1",
"1p84",
"1pp9",
"1ppj",
"1q90",
"1qcr",
"1sqb",
"1sqp",
"1sqq",
"1sqv",
"1sqx",
"1vf5",
"1zrt",
"2a06",
"2bcc",
"2d2c",
"2e74",
"2e75",
"2e76",
"2fyn",
"2fyu"... | 224 | [
"PUB00000640",
"PUB00003404"
] | [
"8329437",
"2509716"
] | [
"Mitochondrial cytochrome b: evolution and structure of the protein.",
"Evolutionary conservation of protein regions in the protonmotive cytochrome b and their possible roles in redox catalysis."
] | [
1993,
1989
] | 2 | [] | [
"IPR048260"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
553,
10695,
234109,
313
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
9,
4,
2,
16,
1926,
107,
1,
6,
86,
1,
1,
9
] | 12 | true | Domain | Cytochrome b/b6, C-terminal | Cytochrome b/b6, C-terminal | Cyt_b/b6_C | 5 |
IPR005801 | 5,801 | ADC synthase | ADC_synthase | Homologous_superfamily | 73,916 | false | false | This domain superfamily is characteristic of ADC synthases, including: Anthranilate synthase aminodeoxyisochorismate synthase/lyase subunit, TrpE, which catalyses the formation of anthranilate (o-aminobenzoate) and pyruvic acid from chorismate and glutamine [ , ]. P-aminobenzoate synthase component I (Aminodeoxychorism... | [
"GO:0009058"
] | [
"biosynthetic process"
] | [
"biological_process"
] | 1 | [
"CATHGENE3D",
"SSF"
] | [
"G3DSA:3.60.120.10",
"SSF56322"
] | [
"",
""
] | [
73791,
73745
] | 2 | [
"EC",
"METACYC",
"METACYC"
] | [
"4.1.3.27",
"PWY-5958",
"PWY-6661"
] | [
"EC:4.1.3.27",
"METACYC:PWY-5958",
"METACYC:PWY-6661"
] | 3 | [
"1i1q",
"1i7q",
"1i7s",
"1k0e",
"1k0g",
"1qdl",
"2eua",
"2fn0",
"2fn1",
"2g5f",
"2i6y",
"3bzm",
"3bzn",
"3gse",
"3h9m",
"3hwo",
"3log",
"3os6",
"3r74",
"3r75",
"3r76",
"3rv6",
"3rv7",
"3rv8",
"3rv9",
"3st6",
"3veh",
"4grh",
"5cwa",
"5jxz",
"5jy4",
"5jy8"... | 54 | [
"PUB00008575",
"PUB00025879",
"PUB00026600",
"PUB00040743",
"PUB00040937",
"PUB00045456"
] | [
"11371633",
"11224570",
"11841211",
"16434053",
"16923875",
"17240978"
] | [
"The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan.",
"Structure of the cooperative allosteric anthranilate synthase from Salmonella typhimurium.",
... | [
2001,
2001,
2002,
2006,
2006,
2007
] | 6 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
1503,
62720,
8266,
15,
1412
] | 5 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
33,
4,
3,
19,
2,
2,
37
] | 7 | true | Homologous_superfamily | ADC synthase | ADC synthase | ADC_synthase | 1 |
IPR005802 | 5,802 | Aminodeoxychorismate synthase, component I | ADC_synth_comp_1 | Family | 12,612 | false | false | Aminodeoxychorismate synthase, component I (pabB) is closely related to anthranilate synthase component I (trpE). The apparent orthologs of pabB in Aquifex aeolicus and Helicobacter pylori 26695 score well below most TrpE proteins because of a different architecture, in which the less strongly conserved N-terminal doma... | [
"GO:0009396"
] | [
"folic acid-containing compound biosynthetic process"
] | [
"biological_process"
] | 1 | [
"NCBIFAM"
] | [
"TIGR00553"
] | [
"pabB"
] | [
12612
] | 1 | [
"EC",
"GP",
"GP",
"GP",
"METACYC",
"METACYC"
] | [
"2.6.1.85",
"GenProp0759",
"GenProp1291",
"GenProp1727",
"PWY-6543",
"PWY-8032"
] | [
"EC:2.6.1.85",
"GP:GenProp0759",
"GP:GenProp1291",
"GP:GenProp1727",
"METACYC:PWY-6543",
"METACYC:PWY-8032"
] | 6 | [
"1k0e",
"1k0g",
"8hx6",
"8hx7",
"8hx8",
"8hx9",
"8rp0",
"8rp1",
"8rp2",
"8rp6"
] | 10 | [] | [] | [] | [] | 0 | [
"IPR019999"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"candidate division MSBL1 archaeon SCGC-AAA382F02",
"unclassified sequences"
] | [
11890,
639,
1,
82
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
4,
1,
2,
1
] | 4 | true | Family | Aminodeoxychorismate synthase, component I | Aminodeoxychorismate synthase, component I | ADC_synth_comp_1 | 6 |
IPR005803 | 5,803 | Fatty acid desaturase type 2, conserved site | FADS-2_CS | Conserved_site | 1,854 | false | false | This conserved region is found at the C-terminal part of family 2 enzymes. Fatty acid desaturases are enzymes that catalyse the insertion of a double bond at the delta position of fatty acids. There seem to be two distinct families of fatty acid desaturases which do not seem to be evolutionary related. Family 1 is comp... | [
"GO:0016491",
"GO:0006633"
] | [
"oxidoreductase activity",
"fatty acid biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PROSITE"
] | [
"PS00574"
] | [
"FATTY_ACID_DESATUR_2"
] | [
1854
] | 1 | [
"EC",
"METACYC",
"METACYC",
"PROSITEDOC"
] | [
"1.14.19.2",
"PWY-5147",
"PWY-5366",
"PDOC00399"
] | [
"EC:1.14.19.2",
"METACYC:PWY-5147",
"METACYC:PWY-5366",
"PROSITEDOC:PDOC00399"
] | 4 | [
"1afr",
"1oq4",
"1oq7",
"1oq9",
"1oqb",
"2j2f",
"2uw1",
"2xz0",
"2xz1",
"4v0j"
] | 10 | [
"PUB00002505",
"PUB00004074",
"PUB00004734",
"PUB00098457",
"PUB00098458"
] | [
"2570068",
"2118597",
"2006187",
"32470559",
"26098317"
] | [
"Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase.",
"Enhancement of chilling tolerance of a cyanobacterium by genetic manipulation of fatty acid desaturation.",
"Stearoyl-acyl-carrier-protein desaturase from higher plants i... | [
1989,
1990,
1991,
2020,
2015
] | 5 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
10,
1844
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
8,
1,
8
] | 3 | true | Conserved_site | Fatty acid desaturase type 2, conserved site | Fatty acid desaturase type 2, conserved site | FADS-2_CS | 2 |
IPR005804 | 5,804 | Fatty acid desaturase domain | FA_desaturase_dom | Domain | 88,712 | false | false | Fatty acid desaturases are enzymes that catalyse the insertion of a double bond at the delta position of fatty acids. There seem to be two distinct families of fatty acid desaturases which do not seem to be evolutionary related. Family 1 is composed of: Stearoyl-CoA desaturase (SCD) ( ) [ ]. Family 2 is composed of: Ba... | [
"GO:0006629"
] | [
"lipid metabolic process"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF00487"
] | [
"FA_desaturase"
] | [
88712
] | 1 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACT... | [
"1.14.19",
"GenProp1339",
"GenProp1452",
"GenProp1587",
"GenProp1597",
"GenProp1665",
"GenProp1671",
"GenProp1690",
"GenProp1761",
"R-BTA-1660661",
"R-BTA-2046105",
"R-BTA-2046106",
"R-BTA-6798695",
"R-BTA-75105",
"R-CEL-1660661",
"R-CEL-2046105",
"R-CEL-2046106",
"R-CEL-6798695",
... | [
"EC:1.14.19",
"GP:GenProp1339",
"GP:GenProp1452",
"GP:GenProp1587",
"GP:GenProp1597",
"GP:GenProp1665",
"GP:GenProp1671",
"GP:GenProp1690",
"GP:GenProp1761",
"REACTOME:R-BTA-1660661",
"REACTOME:R-BTA-2046105",
"REACTOME:R-BTA-2046106",
"REACTOME:R-BTA-6798695",
"REACTOME:R-BTA-75105",
"R... | 48 | [
"4ymk",
"6wf2",
"8f6t",
"8sbb"
] | 4 | [
"PUB00002505",
"PUB00004074",
"PUB00004734",
"PUB00098457",
"PUB00098458"
] | [
"2570068",
"2118597",
"2006187",
"32470559",
"26098317"
] | [
"Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase.",
"Enhancement of chilling tolerance of a cyanobacterium by genetic manipulation of fatty acid desaturation.",
"Stearoyl-acyl-carrier-protein desaturase from higher plants i... | [
1989,
1990,
1991,
2020,
2015
] | 5 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
24,
46363,
41453,
43,
829
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
72,
7,
8,
21,
31,
24,
6,
35,
39,
1,
2,
64
] | 12 | true | Domain | Fatty acid desaturase domain | Fatty acid desaturase domain | FA_desaturase_dom | 5 |
IPR005805 | 5,805 | Rieske iron-sulphur protein, C-terminal | Rieske_Fe-S_prot_C | Domain | 28,043 | false | false | Ubiquinol-cytochrome c reductase (bc1 complex or complex III) is an enzyme complex of bacterial and mitochondrial oxidative phosphorylation systems It catalyses the oxidoreduction of the mobile redox components ubiquinol and cytochrome c, generating an electrochemical potential, which is linked to ATP synthesis [ , ]. ... | [
"GO:0051537",
"GO:0016020"
] | [
"2 iron, 2 sulfur cluster binding",
"membrane"
] | [
"molecular_function",
"cellular_component"
] | 2 | [
"PRINTS"
] | [
"PR00162"
] | [
"RIESKE"
] | [
28043
] | 1 | [
"EC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"7.1.1",
"R-BTA-611105",
"R-BTA-9865881",
"R-CEL-9865881",
"R-DME-611105",
"R-DME-9865881",
"R-DRE-9865881",
"R-GGA-611105",
"R-GGA-9865881",
"R-HSA-611105",
"R-HSA-9865881",
"R-MMU-611105",
"R-MMU-9865881",
"R-RNO-611105",
"R-RNO-9865881",
"R-SCE-611105",
"R-SCE-9865878",
"R-SCE-9... | [
"EC:7.1.1",
"REACTOME:R-BTA-611105",
"REACTOME:R-BTA-9865881",
"REACTOME:R-CEL-9865881",
"REACTOME:R-DME-611105",
"REACTOME:R-DME-9865881",
"REACTOME:R-DRE-9865881",
"REACTOME:R-GGA-611105",
"REACTOME:R-GGA-9865881",
"REACTOME:R-HSA-611105",
"REACTOME:R-HSA-9865881",
"REACTOME:R-MMU-611105",
... | 21 | [
"1bcc",
"1be3",
"1bgy",
"1ezv",
"1g8j",
"1g8k",
"1jm1",
"1kb9",
"1kyo",
"1l0l",
"1l0n",
"1ntk",
"1ntm",
"1ntz",
"1nu1",
"1nyk",
"1p84",
"1pp9",
"1ppj",
"1q90",
"1qcr",
"1rfs",
"1rie",
"1sqb",
"1sqp",
"1sqq",
"1sqv",
"1sqx",
"1vf5",
"1zrt",
"2a06",
"2bcc"... | 252 | [
"PUB00001341",
"PUB00001342",
"PUB00002441",
"PUB00004558"
] | [
"2986972",
"3004982",
"2820981",
"1391772"
] | [
"The primary structure of the iron-sulfur subunit of ubiquinol-cytochrome c reductase from Neurospora, determined by cDNA and gene sequencing.",
"Nucleotide sequence and transcription of the fbc operon from Rhodopseudomonas sphaeroides. Evaluation of the deduced amino acid sequences of the FeS protein, cytochrome... | [
1985,
1986,
1987,
1992
] | 4 | [
"IPR017941"
] | [
"IPR038010"
] | 1 | 1 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
319,
20644,
6544,
536
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
11,
1,
1,
4,
4,
1,
1,
7,
3,
1,
1,
20
] | 12 | true | Domain | Rieske iron-sulphur protein, C-terminal | Rieske iron-sulphur protein, C-terminal | Rieske_Fe-S_prot_C | 3 |
IPR005807 | 5,807 | SecE subunit of protein translocation complex, bacterial-like | SecE_bac | Family | 23,685 | false | false | Secretion across the inner membrane in some Gram-negative bacteria occurs via the preprotein translocase pathway. Proteins are produced in the cytoplasm as precursors, and require a chaperone subunit to direct them to the translocase component [ ]. From there, the mature proteins are either targeted to the outer membra... | [
"GO:0008320",
"GO:0009306",
"GO:0016020"
] | [
"protein transmembrane transporter activity",
"protein secretion",
"membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PRINTS",
"PANTHER",
"NCBIFAM"
] | [
"PR01650",
"PTHR33910",
"TIGR00964"
] | [
"SECETRNLCASE",
"",
"secE_bact"
] | [
7027,
19458,
23673
] | 3 | [
"GP",
"GP",
"GP",
"REACTOME",
"REACTOME"
] | [
"GenProp0209",
"GenProp1132",
"GenProp1176",
"R-HSA-1222387",
"R-HSA-9760173"
] | [
"GP:GenProp0209",
"GP:GenProp1132",
"GP:GenProp1176",
"REACTOME:R-HSA-1222387",
"REACTOME:R-HSA-9760173"
] | 5 | [
"2akh",
"2aki",
"2zjs",
"2zqp",
"3bo0",
"3bo1",
"3din",
"3dl8",
"3j45",
"3j46",
"4v6m",
"4v7i",
"5abb",
"5aww",
"5ch4",
"5eul",
"5gae",
"5mg3",
"5nco",
"6itc",
"6r7l",
"7xha",
"7xhb",
"8y9y",
"8y9z",
"8ya0",
"8ya2",
"8ya3",
"8yas"
] | 29 | [
"PUB00007064",
"PUB00007065",
"PUB00007066",
"PUB00007187"
] | [
"2202721",
"11336818",
"10418149",
"12167867"
] | [
"The sec and prl genes of Escherichia coli.",
"SecB, a molecular chaperone with two faces.",
"Effects of pre-protein overexpression on SecB synthesis in Escherichia coli.",
"Three-dimensional structure of the bacterial protein-translocation complex SecYEG."
] | [
1990,
2001,
1999,
2002
] | 4 | [
"IPR001901"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
2,
23114,
144,
425
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)"
] | [
4,
1
] | 2 | true | Family | SecE subunit of protein translocation complex, bacterial-like | SecE subunit of protein translocation complex, bacterial-like | SecE_bac | 9 |
IPR005809 | 5,809 | Succinate--CoA ligase-like, beta subunit | Succ_CoA_ligase-like_bsu | Family | 28,869 | false | false | This entry represents a group of different enzymes that share a similar catalytic mechanism which involves the phosphorylation by ATP (or GTP) of a specific histidine residue in the active site. These enzymes are: Succinate--CoA ligase (GDP-forming ( ) [ ] is a mitochondrial enzyme that catalyses the substrate level ph... | [
"GO:0006099"
] | [
"tricarboxylic acid cycle"
] | [
"biological_process"
] | 1 | [
"HAMAP",
"PIRSF",
"NCBIFAM"
] | [
"MF_00558",
"PIRSF001554",
"TIGR01016"
] | [
"Succ_CoA_beta",
"SucCS_beta",
"sucCoAbeta"
] | [
26515,
28441,
26627
] | 3 | [
"EC",
"EC",
"GP",
"GP",
"GP",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"6.2.1",
"6.2.1.5",
"GenProp0033",
"GenProp1201",
"GenProp1693",
"PWY-5392",
"PWY-5537",
"PWY-5538",
"PWY-5690",
"PWY-6728",
"PWY-6969",
"PWY-7384",
"PWY-8347",
"PWY-8354",
"R-BTA-71403",
"R-BTA-9837999",
"R-CEL-71403",
"R-CEL-9837999",
"R-DDI-71403",
"R-HSA-71403",
"R-HSA-98... | [
"EC:6.2.1",
"EC:6.2.1.5",
"GP:GenProp0033",
"GP:GenProp1201",
"GP:GenProp1693",
"METACYC:PWY-5392",
"METACYC:PWY-5537",
"METACYC:PWY-5538",
"METACYC:PWY-5690",
"METACYC:PWY-6728",
"METACYC:PWY-6969",
"METACYC:PWY-7384",
"METACYC:PWY-8347",
"METACYC:PWY-8354",
"REACTOME:R-BTA-71403",
"R... | 25 | [
"1cqi",
"1cqj",
"1euc",
"1eud",
"1jkj",
"1jll",
"1scu",
"2fp4",
"2fpg",
"2fpi",
"2fpp",
"2nu6",
"2nu7",
"2nu8",
"2nu9",
"2nua",
"2scu",
"3ufx",
"4xx0",
"5cae",
"6g4q",
"6hxj",
"6hxq",
"6mel",
"6mgg",
"6pfn",
"6wcv",
"6xru",
"7jfp",
"7jj0",
"7jkr",
"7jmk"... | 38 | [
"PUB00000280",
"PUB00001411",
"PUB00002257",
"PUB00005004",
"PUB00015785",
"PUB00153675",
"PUB00153676"
] | [
"3002435",
"1371749",
"7961516",
"8401211",
"12376641",
"37404184",
"37414148"
] | [
"Primary structure of the succinyl-CoA synthetase of Escherichia coli.",
"Cloning and expression of a human ATP-citrate lyase cDNA.",
"Genetics of the serine cycle in Methylobacterium extorquens AM1: identification, sequence, and mutation of three new genes involved in C1 assimilation, orf4, mtkA, and mtkB.",
... | [
1985,
1992,
1994,
1993,
2002,
2023,
2023
] | 7 | [] | [
"IPR034722",
"IPR034723"
] | 0 | 2 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
723,
20297,
7428,
421
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
4,
2,
4,
6,
1,
15,
5,
1,
2,
11,
1,
1,
16
] | 13 | true | Family | Succinate--CoA ligase-like, beta subunit | Succinate--CoA ligase-like, beta subunit | Succ_CoA_ligase-like_bsu | 3 |
IPR005810 | 5,810 | Succinyl-CoA ligase, alpha subunit | CoA_lig_alpha | Family | 26,420 | false | false | This entry describes succinyl-CoA synthetase alpha subunits, but does not discriminate between GTP-specific and ATP-specific reactions. ATP citrate lyases appear to form an outgroup, and are not included in this entry. There are four different enzymes that share a similar catalytic mechanism which involves the phosphor... | [
"GO:0003824"
] | [
"catalytic activity"
] | [
"molecular_function"
] | 1 | [
"HAMAP",
"PIRSF",
"NCBIFAM"
] | [
"MF_01988",
"PIRSF001553",
"TIGR01019"
] | [
"Succ_CoA_alpha",
"SucCS_alpha",
"sucCoAalpha"
] | [
24938,
25820,
25046
] | 3 | [
"EC",
"EC",
"GP",
"GP",
"GP",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"PROSITEDOC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"6.2.1",
"6.2.1.5",
"GenProp0033",
"GenProp1201",
"GenProp1693",
"PWY-5392",
"PWY-5537",
"PWY-5538",
"PWY-5690",
"PWY-6728",
"PWY-6969",
"PWY-7384",
"PWY-8347",
"PWY-8354",
"PDOC00335",
"R-CEL-71403",
"R-DDI-71403",
"R-DME-71403",
"R-HSA-71403",
"R-MMU-71403",
"R-RNO-71403",
... | [
"EC:6.2.1",
"EC:6.2.1.5",
"GP:GenProp0033",
"GP:GenProp1201",
"GP:GenProp1693",
"METACYC:PWY-5392",
"METACYC:PWY-5537",
"METACYC:PWY-5538",
"METACYC:PWY-5690",
"METACYC:PWY-6728",
"METACYC:PWY-6969",
"METACYC:PWY-7384",
"METACYC:PWY-8347",
"METACYC:PWY-8354",
"PROSITEDOC:PDOC00335",
"R... | 24 | [
"1cqi",
"1cqj",
"1euc",
"1eud",
"1jkj",
"1jll",
"1oi7",
"1scu",
"2fp4",
"2fpg",
"2fpi",
"2fpp",
"2nu6",
"2nu7",
"2nu8",
"2nu9",
"2nua",
"2scu",
"2yv1",
"2yv2",
"3ufx",
"4xx0",
"5cae",
"6g4q",
"6mel",
"6mgg",
"6pfn",
"6wcv",
"6xru",
"7jfp",
"7jj0",
"7jkr"... | 39 | [
"PUB00000280",
"PUB00001411",
"PUB00002257",
"PUB00005004"
] | [
"3002435",
"1371749",
"7961516",
"8401211"
] | [
"Primary structure of the succinyl-CoA synthetase of Escherichia coli.",
"Cloning and expression of a human ATP-citrate lyase cDNA.",
"Genetics of the serine cycle in Methylobacterium extorquens AM1: identification, sequence, and mutation of three new genes involved in C1 assimilation, orf4, mtkA, and mtkB.",
... | [
1985,
1992,
1994,
1993
] | 4 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
718,
20076,
5181,
445
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
6,
2,
1,
3,
1,
4,
1,
1,
1,
5,
1,
1,
11
] | 13 | true | Family | Succinyl-CoA ligase, alpha subunit | Succinyl-CoA ligase, alpha subunit | CoA_lig_alpha | 7 |
IPR005811 | 5,811 | ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain | SUCC_ACL_C | Domain | 66,190 | false | false | This entry represents a domain found in both the alpha and beta chains of succinyl-CoA synthase ( (GDP-forming) and (ADP-forming)) [ , ]. This domain can also be found in ATP citrate synthase ( , [ ]) and malate-CoA ligase ( ). Some members of the domain utilise ATP others use GTP. | [
"GO:0003824"
] | [
"catalytic activity"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF00549"
] | [
"Ligase_CoA"
] | [
66190
] | 1 | [
"EC",
"EC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"... | [
"6.2.1",
"6.2.1.5",
"PWY-5392",
"PWY-5537",
"PWY-5538",
"PWY-5690",
"PWY-6728",
"PWY-6969",
"PWY-7384",
"PWY-8347",
"PWY-8354",
"R-BTA-6798695",
"R-BTA-71403",
"R-BTA-75105",
"R-BTA-9837999",
"R-CEL-6798695",
"R-CEL-71403",
"R-CEL-75105",
"R-CEL-9837999",
"R-DDI-6798695",
"R-... | [
"EC:6.2.1",
"EC:6.2.1.5",
"METACYC:PWY-5392",
"METACYC:PWY-5537",
"METACYC:PWY-5538",
"METACYC:PWY-5690",
"METACYC:PWY-6728",
"METACYC:PWY-6969",
"METACYC:PWY-7384",
"METACYC:PWY-8347",
"METACYC:PWY-8354",
"REACTOME:R-BTA-6798695",
"REACTOME:R-BTA-71403",
"REACTOME:R-BTA-75105",
"REACTOM... | 40 | [
"1cqi",
"1cqj",
"1euc",
"1eud",
"1jkj",
"1jll",
"1oi7",
"1scu",
"2fp4",
"2fpg",
"2fpi",
"2fpp",
"2nu6",
"2nu7",
"2nu8",
"2nu9",
"2nua",
"2scu",
"2yv1",
"2yv2",
"3dmy",
"3mwd",
"3mwe",
"3pff",
"3ufx",
"4xx0",
"5cae",
"5tde",
"5tdf",
"5tdm",
"5tdz",
"5te1"... | 75 | [
"PUB00015984",
"PUB00036671",
"PUB00075004"
] | [
"9917402",
"10873456",
"23932781"
] | [
"A detailed structural description of Escherichia coli succinyl-CoA synthetase.",
"Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase.",
"Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth."
] | [
1999,
2000,
2013
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Mimiviridae",
"unclassified sequences"
] | [
1485,
43418,
20139,
5,
1143
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
18,
6,
17,
14,
4,
26,
13,
4,
6,
24,
2,
3,
41
] | 13 | true | Domain | ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain | ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain | SUCC_ACL_C | 4 |
IPR005813 | 5,813 | Large ribosomal subunit protein bL20 | Ribosomal_bL20 | Family | 40,859 | false | false | This entry represents the large ribosomal subunit protein family bL20 that contains members from eubacteria, as well as their mitochondrial and plastid homologs. bL20 is an assembly protein, required for the first in vitro reconstitution step of the 50S ribosomal subunit, but does not seem to be essential for ribosome ... | [
"GO:0003735",
"GO:0019843",
"GO:0006412",
"GO:0005840"
] | [
"structural constituent of ribosome",
"rRNA binding",
"translation",
"ribosome"
] | [
"molecular_function",
"molecular_function",
"biological_process",
"cellular_component"
] | 4 | [
"HAMAP",
"PFAM",
"PRINTS",
"PANTHER",
"NCBIFAM",
"CDD"
] | [
"MF_00382",
"PF00453",
"PR00062",
"PTHR10986",
"TIGR01032",
"cd07026"
] | [
"Ribosomal_bL20",
"Ribosomal_L20",
"RIBOSOMALL20",
"",
"rplT_bact",
"Ribosomal_L20"
] | [
38008,
40782,
39808,
40580,
39641,
39538
] | 6 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-5368286",
"R-HSA-5389840",
"R-HSA-5419276",
"R-HSA-9937383",
"R-MMU-5389840",
"R-MMU-5419276",
"R-MMU-9937383"
] | [
"REACTOME:R-HSA-5368286",
"REACTOME:R-HSA-5389840",
"REACTOME:R-HSA-5419276",
"REACTOME:R-HSA-9937383",
"REACTOME:R-MMU-5389840",
"REACTOME:R-MMU-5419276",
"REACTOME:R-MMU-9937383"
] | 7 | [
"1gyz",
"1nkw",
"1nwx",
"1nwy",
"1sm1",
"1vvj",
"1vy4",
"1vy5",
"1vy6",
"1vy7",
"1xbp",
"2ftc",
"2ghj",
"2j28",
"2rdo",
"2zjp",
"2zjq",
"2zjr",
"3bbx",
"3cf5",
"3dll",
"3iy9",
"3j3v",
"3j3w",
"3j5l",
"3j7y",
"3j7z",
"3j8g",
"3j9m",
"3j9w",
"3j9y",
"3j9z"... | 1,262 | [
"PUB00007068",
"PUB00007069",
"PUB00007070",
"PUB00041053",
"PUB00079709",
"PUB00079710",
"PUB00079711",
"PUB00079712",
"PUB00079713",
"PUB00079714"
] | [
"11297922",
"11290319",
"11114498",
"16977336",
"19399222",
"18037435",
"17439971",
"17289755",
"15916597",
"1453449"
] | [
"Atomic structures at last: the ribosome in 2000.",
"The ribosome in focus.",
"The end of the beginning: structural studies of ribosomal proteins.",
"Coexistence of two protein folding states in the crystal structure of ribosomal protein L20.",
"The role of disordered ribosomal protein extensions in the ear... | [
2001,
2001,
2000,
2006,
2009,
2008,
2007,
2007,
2005,
1992
] | 10 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Nitrosopumilus salarius BD31",
"Eukaryota",
"Siphoviridae sp. ctjdk2",
"unclassified sequences"
] | [
23314,
1,
17032,
1,
511
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
8,
1,
1,
1,
1,
3,
4,
8,
4,
6
] | 10 | true | Family | Large ribosomal subunit protein bL20 | Large ribosomal subunit protein bL20 | Ribosomal_bL20 | 9 |
IPR005814 | 5,814 | Aminotransferase class-III | Aminotrans_3 | Family | 195,233 | false | false | Aminotransferases share certain mechanistic features with other pyridoxalphosphate-dependent enzymes, such as the covalent binding of the pyridoxalphosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped into subfamilies [ ]. One of these, called class-III, includes... | [
"GO:0030170"
] | [
"pyridoxal phosphate binding"
] | [
"molecular_function"
] | 1 | [
"PFAM",
"PIRSF",
"CDD"
] | [
"PF00202",
"PIRSF000521",
"cd00610"
] | [
"Aminotran_3",
"Transaminase_4ab_Lys_Orn",
"OAT_like"
] | [
195232,
117312,
174277
] | 3 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"PROSITEDOC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
... | [
"5.4.3.8",
"GenProp1276",
"GenProp1279",
"GenProp1280",
"GenProp1288",
"GenProp1362",
"GenProp1377",
"GenProp1428",
"GenProp1466",
"GenProp1472",
"GenProp1506",
"GenProp1523",
"GenProp1577",
"GenProp1579",
"GenProp1701",
"PWY-5188",
"PDOC00519",
"R-BTA-1483213",
"R-CEL-1442490",
... | [
"EC:5.4.3.8",
"GP:GenProp1276",
"GP:GenProp1279",
"GP:GenProp1280",
"GP:GenProp1288",
"GP:GenProp1362",
"GP:GenProp1377",
"GP:GenProp1428",
"GP:GenProp1466",
"GP:GenProp1472",
"GP:GenProp1506",
"GP:GenProp1523",
"GP:GenProp1577",
"GP:GenProp1579",
"GP:GenProp1701",
"METACYC:PWY-5188",
... | 53 | [
"1d7r",
"1d7s",
"1d7u",
"1d7v",
"1dgd",
"1dge",
"1dka",
"1dty",
"1gbn",
"1m0n",
"1m0o",
"1m0p",
"1m0q",
"1mgv",
"1mly",
"1mlz",
"1oat",
"1ohv",
"1ohw",
"1ohy",
"1qj3",
"1qj5",
"1s06",
"1s07",
"1s08",
"1s09",
"1s0a",
"1sf2",
"1sff",
"1szk",
"1szs",
"1szu"... | 338 | [
"PUB00002716",
"PUB00008007",
"PUB00017555",
"PUB00023027",
"PUB00056810",
"PUB00057659",
"PUB00085096",
"PUB00085097",
"PUB00085098"
] | [
"1618757",
"2199330",
"9514614",
"8342040",
"1092681",
"2500426",
"3754226",
"10989446",
"2349227"
] | [
"The primary structure of omega-amino acid:pyruvate aminotransferase.",
"Escherichia coli and Saccharomyces cerevisiae acetylornithine aminotransferase: evolutionary relationship with ornithine aminotransferase.",
"Two genes involved in the 1,3-diaminopropane production pathway in Haemophilus influenzae.",
"D... | [
1992,
1990,
1998,
1993,
1975,
1989,
1986,
2000,
1990
] | 9 | [] | [
"IPR004631",
"IPR004632",
"IPR004636",
"IPR004637",
"IPR004639",
"IPR005815",
"IPR010164",
"IPR017657",
"IPR017747",
"IPR049691"
] | 0 | 10 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
3616,
155727,
32293,
58,
3539
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
41,
5,
15,
9,
8,
24,
19,
7,
27,
25,
4,
7,
109
] | 13 | true | Family | Aminotransferase class-III | Aminotransferase class-III | Aminotrans_3 | 6 |
IPR005815 | 5,815 | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA | BioA | Family | 15,576 | false | false | BioA is an adenosylmethionine-8-amino-7-oxononanoate aminotransferase that functions in biotin synthesis. It utilises S-adenosyl-L-methionine (SAM) to transaminate the biotin precursor 7-keto-8-aminopelargonic acid and form the next intermediate in the pathway, 7, 8-diaminopelargonic acid [ ]. It is currently the only ... | [
"GO:0004015",
"GO:0009102"
] | [
"adenosylmethionine-8-amino-7-oxononanoate transaminase activity",
"biotin biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_00834",
"TIGR00508"
] | [
"BioA",
"bioA"
] | [
15445,
15523
] | 2 | [
"EC",
"GP",
"GP",
"GP"
] | [
"2.6.1.62",
"GenProp0036",
"GenProp1377",
"GenProp1577"
] | [
"EC:2.6.1.62",
"GP:GenProp0036",
"GP:GenProp1377",
"GP:GenProp1577"
] | 4 | [
"1dty",
"1mgv",
"1mly",
"1mlz",
"1qj3",
"1qj5",
"1s06",
"1s07",
"1s08",
"1s09",
"1s0a",
"3bv0",
"3dod",
"3drd",
"3du4",
"3lv2",
"3tft",
"3tfu",
"4cxq",
"4cxr",
"4mqp",
"4mqq",
"4mqr",
"4w1v",
"4w1w",
"4w1x",
"4wya",
"4wyc",
"4wyd",
"4wye",
"4wyf",
"4wyg"... | 47 | [
"PUB00056810",
"PUB00056811"
] | [
"1092681",
"15880481"
] | [
"Purification and properties of 7, 8-diaminopelargonic acid aminotransferase.",
"Removing a bottleneck in the Bacillus subtilis biotin pathway: bioA utilizes lysine rather than S-adenosylmethionine as the amino donor in the KAPA-to-DAPA reaction."
] | [
1975,
2005
] | 2 | [
"IPR005814"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
98,
15130,
199,
149
] | 4 | [
"Escherichia coli (strain K12)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
1,
1
] | 2 | true | Family | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA | Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA | BioA | 8 |
IPR005818 | 5,818 | Linker histone H1/H5, domain H15 | Histone_H1/H5_H15 | Domain | 27,812 | false | false | Histone proteins have central roles in both chromatin organisation (as structural units of the nucleosome) and gene regulation (as dynamic components that have a direct impact on DNA transcription and replication). Eukaryotic DNA wraps around a histone octamer to form a nucleosome, the first order of compaction of euka... | [
"GO:0003677",
"GO:0006334",
"GO:0000786"
] | [
"DNA binding",
"nucleosome assembly",
"nucleosome"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PFAM",
"PROFILE",
"SMART",
"CDD"
] | [
"PF00538",
"PS51504",
"SM00526",
"cd00073"
] | [
"Linker_histone",
"H15",
"H15",
"H15"
] | [
25190,
27094,
25851,
17307
] | 4 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-2559584",
"R-HSA-140342",
"R-HSA-2559584",
"R-HSA-3214847",
"R-HSA-6804758",
"R-HSA-8866654",
"R-HSA-9821993",
"R-MMU-140342",
"R-MMU-2559584",
"R-MMU-3214847",
"R-MMU-6804758",
"R-MMU-8866654",
"R-RNO-140342",
"R-RNO-3214847",
"R-RNO-6804758"
] | [
"REACTOME:R-CEL-2559584",
"REACTOME:R-HSA-140342",
"REACTOME:R-HSA-2559584",
"REACTOME:R-HSA-3214847",
"REACTOME:R-HSA-6804758",
"REACTOME:R-HSA-8866654",
"REACTOME:R-HSA-9821993",
"REACTOME:R-MMU-140342",
"REACTOME:R-MMU-2559584",
"REACTOME:R-MMU-3214847",
"REACTOME:R-MMU-6804758",
"REACTOME:... | 15 | [
"1ghc",
"1hst",
"1uhm",
"1uss",
"1ust",
"1yqa",
"2lso",
"2rqp",
"4qlc",
"5nl0",
"5wcu",
"6hq1",
"6l9z",
"6la2",
"6la8",
"6la9",
"6lab",
"6n88",
"6n89",
"7c0j",
"7cow",
"7dbp",
"7k5x",
"7k5y",
"7k60",
"7k63",
"7kbf",
"7pet",
"7peu",
"7pex",
"7pez",
"7pf0"... | 62 | [
"PUB00004142",
"PUB00004625",
"PUB00031779",
"PUB00055532",
"PUB00055533",
"PUB00055534"
] | [
"8384699",
"3463990",
"14654695",
"16345076",
"8218199",
"15313893"
] | [
"Crystal structure of globular domain of histone H5 and its implications for nucleosome binding.",
"Nuclear magnetic resonance study of the globular domain of chicken histone H5: resonance assignment and secondary structure.",
"The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged h... | [
1993,
1986,
2003,
2006,
1993,
2004
] | 6 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Candidatus Heimdallarchaeum endolithica",
"Eukaryota",
"Viruses",
"organismal metagenomes"
] | [
9,
1,
27793,
7,
2
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
78,
9,
52,
16,
48,
46,
2,
33,
37,
1,
153
] | 11 | true | Domain | Linker histone H1/H5, domain H15 | Linker histone H1/H5, domain H15 | Histone_H1/H5_H15 | 2 |
IPR005819 | 5,819 | Linker histone H1/H5 | H1/H5 | Family | 17,963 | false | false | Histone proteins have central roles in both chromatin organisation (as structural units of the nucleosome) and gene regulation (as dynamic components that have a direct impact on DNA transcription and replication). Eukaryotic DNA wraps around a histone octamer to form a nucleosome, the first order of compaction of euka... | [
"GO:0003677",
"GO:0030527",
"GO:0006334",
"GO:0000786"
] | [
"DNA binding",
"structural constituent of chromatin",
"nucleosome assembly",
"nucleosome"
] | [
"molecular_function",
"molecular_function",
"biological_process",
"cellular_component"
] | 4 | [
"PRINTS"
] | [
"PR00624"
] | [
"HISTONEH5"
] | [
17963
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-CEL-2559584",
"R-HSA-140342",
"R-HSA-2559584",
"R-MMU-140342",
"R-MMU-2559584",
"R-RNO-140342"
] | [
"REACTOME:R-CEL-2559584",
"REACTOME:R-HSA-140342",
"REACTOME:R-HSA-2559584",
"REACTOME:R-MMU-140342",
"REACTOME:R-MMU-2559584",
"REACTOME:R-RNO-140342"
] | 6 | [
"1ghc",
"1hst",
"2rqp",
"4qlc",
"5nl0",
"5wcu",
"6hq1",
"6l9z",
"6la2",
"6la8",
"6la9",
"6lab",
"6n88",
"6n89",
"7c0j",
"7cow",
"7dbp",
"7k5x",
"7k5y",
"7k60",
"7k63",
"7pet",
"7peu",
"7pex",
"7pez",
"7pf0",
"7pf2",
"7pf3",
"7pf5",
"7pf6",
"7pfa",
"7pfc"... | 55 | [
"PUB00004142",
"PUB00004625",
"PUB00031779",
"PUB00055532",
"PUB00055533"
] | [
"8384699",
"3463990",
"14654695",
"16345076",
"8218199"
] | [
"Crystal structure of globular domain of histone H5 and its implications for nucleosome binding.",
"Nuclear magnetic resonance study of the globular domain of chicken histone H5: resonance assignment and secondary structure.",
"The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged h... | [
1993,
1986,
2003,
2006,
1993
] | 5 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"metagenomes"
] | [
29,
1848,
15959,
23,
104
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
12,
8,
30,
7,
15,
23,
3,
7,
22,
1,
53
] | 11 | true | Family | Linker histone H1/H5 | Linker histone H1/H5 | H1/H5 | 3 |
IPR005821 | 5,821 | Ion transport domain | Ion_trans_dom | Domain | 241,867 | false | false | This domain is found in sodium, potassium, and calcium ion channels proteins. The proteins have 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some Na channel proteins the domain is repeated four times, whereas in others (e.g. K channels) the protein forms a tetr... | [
"GO:0005216",
"GO:0006811",
"GO:0055085",
"GO:0016020"
] | [
"monoatomic ion channel activity",
"monoatomic ion transport",
"transmembrane transport",
"membrane"
] | [
"molecular_function",
"biological_process",
"biological_process",
"cellular_component"
] | 4 | [
"PFAM"
] | [
"PF00520"
] | [
"Ion_trans"
] | [
241867
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-1296052",
"R-BTA-1296072",
"R-BTA-2485179",
"R-BTA-2514859",
"R-BTA-3295583",
"R-BTA-5576894",
"R-CEL-114508",
"R-CEL-1300642",
"R-CEL-139853",
"R-CEL-2485179",
"R-CEL-2514859",
"R-CEL-3295583",
"R-CEL-381676",
"R-CEL-5576890",
"R-CEL-5578775",
"R-CEL-5620916",
"R-CEL-9717207"... | [
"REACTOME:R-BTA-1296052",
"REACTOME:R-BTA-1296072",
"REACTOME:R-BTA-2485179",
"REACTOME:R-BTA-2514859",
"REACTOME:R-BTA-3295583",
"REACTOME:R-BTA-5576894",
"REACTOME:R-CEL-114508",
"REACTOME:R-CEL-1300642",
"REACTOME:R-CEL-139853",
"REACTOME:R-CEL-2485179",
"REACTOME:R-CEL-2514859",
"REACTOME:... | 151 | [
"1orq",
"1ors",
"2a0l",
"2a79",
"2kyh",
"2r9r",
"2zd9",
"3beh",
"3j8h",
"3j9p",
"3jav",
"3jbr",
"3lnm",
"3lut",
"3rvy",
"3rvz",
"3rw0",
"3wkv",
"3zjz",
"4bgn",
"4cbc",
"4chv",
"4chw",
"4dxw",
"4ekw",
"4f4l",
"4g7v",
"4g7y",
"4g80",
"4jta",
"4jtc",
"4jtd"... | 1,115 | [
"PUB00154567",
"PUB00154568"
] | [
"10620513",
"27108797"
] | [
"Ca2+-calmodulin inhibits Ca2+ release mediated by type-1, -2 and -3 inositol trisphosphate receptors.",
"Recessive and Dominant De Novo ITPR1 Mutations Cause Gillespie Syndrome."
] | [
2000,
2016
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"metagenomes"
] | [
324,
12493,
7,
228829,
214
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
152,
162,
913,
232,
593,
415,
1,
66,
527,
1,
1,
181
] | 12 | true | Domain | Ion transport domain | Ion transport domain | Ion_trans_dom | 6 |
IPR005822 | 5,822 | Large ribosomal subunit protein uL13 | Ribosomal_uL13 | Family | 37,056 | false | false | Ribosomal protein uL13 is one of the proteins from the large ribosomal subunit [ ]. In Escherichia coli, uL13 is known to be one of the early assembly proteins of the 50S ribosomal subunit. uL13 proteins were previously known as L13 from bacteria, L16 from yeast and L13A from human. Ribosomes are the particles that cat... | [
"GO:0003735",
"GO:0006412",
"GO:0005840"
] | [
"structural constituent of ribosome",
"translation",
"ribosome"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"HAMAP",
"PFAM",
"PANTHER",
"CDD"
] | [
"MF_01366",
"PF00572",
"PTHR11545",
"cd00392"
] | [
"Ribosomal_uL13",
"Ribosomal_L13",
"",
"Ribosomal_L13"
] | [
34390,
36691,
36414,
35033
] | 4 | [
"PROSITEDOC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACT... | [
"PDOC00625",
"R-BTA-156827",
"R-BTA-1799339",
"R-BTA-5389840",
"R-BTA-5419276",
"R-BTA-6791226",
"R-BTA-72689",
"R-BTA-72706",
"R-BTA-975956",
"R-BTA-975957",
"R-BTA-9937383",
"R-CEL-156827",
"R-CEL-1799339",
"R-CEL-72689",
"R-CEL-72706",
"R-CEL-975956",
"R-CEL-975957",
"R-DDI-1568... | [
"PROSITEDOC:PDOC00625",
"REACTOME:R-BTA-156827",
"REACTOME:R-BTA-1799339",
"REACTOME:R-BTA-5389840",
"REACTOME:R-BTA-5419276",
"REACTOME:R-BTA-6791226",
"REACTOME:R-BTA-72689",
"REACTOME:R-BTA-72706",
"REACTOME:R-BTA-975956",
"REACTOME:R-BTA-975957",
"REACTOME:R-BTA-9937383",
"REACTOME:R-CEL-1... | 78 | [
"1ffk",
"1j3a",
"1jj2",
"1k73",
"1k8a",
"1k9m",
"1kc8",
"1kd1",
"1kqs",
"1m1k",
"1m90",
"1ml5",
"1n8r",
"1nji",
"1nkw",
"1nwx",
"1nwy",
"1q7y",
"1q81",
"1q82",
"1q86",
"1qvf",
"1qvg",
"1s72",
"1sm1",
"1vq4",
"1vq5",
"1vq6",
"1vq7",
"1vq8",
"1vq9",
"1vqk"... | 1,979 | [
"PUB00002889",
"PUB00007068",
"PUB00007069",
"PUB00007070"
] | [
"8119894",
"11297922",
"11290319",
"11114498"
] | [
"A leucine zipper-like motif and a basic region-leucine zipper-like element in rat ribosomal protein L13a. Identification of the tum- transplantation antigen P198.",
"Atomic structures at last: the ribosome in 2000.",
"The ribosome in focus.",
"The end of the beginning: structural studies of ribosomal protein... | [
1994,
2001,
2001,
2000
] | 4 | [] | [
"IPR005755",
"IPR005823"
] | 0 | 2 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
920,
23718,
11832,
586
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
21,
2,
3,
4,
1,
15,
16,
3,
24,
10,
3,
4,
35
] | 13 | true | Family | Large ribosomal subunit protein uL13 | Large ribosomal subunit protein uL13 | Ribosomal_uL13 | 9 |
IPR005824 | 5,824 | KOW | KOW | Domain | 73,904 | false | false | The KOW (Kyprides, Ouzounis, Woese) motif is found in a variety of ribosomal proteins and the bacterial transcription antitermination proteins NusG [ ]. | [] | [] | [] | 0 | [
"PFAM",
"SMART"
] | [
"PF00467",
"SM00739"
] | [
"KOW",
"KOW"
] | [
61920,
66884
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOM... | [
"R-BTA-156827",
"R-BTA-1799339",
"R-BTA-5389840",
"R-BTA-5419276",
"R-BTA-6791226",
"R-BTA-72649",
"R-BTA-72689",
"R-BTA-72695",
"R-BTA-72702",
"R-BTA-72706",
"R-BTA-975956",
"R-BTA-975957",
"R-BTA-9937383",
"R-CEL-112382",
"R-CEL-113418",
"R-CEL-156827",
"R-CEL-1799339",
"R-CEL-53... | [
"REACTOME:R-BTA-156827",
"REACTOME:R-BTA-1799339",
"REACTOME:R-BTA-5389840",
"REACTOME:R-BTA-5419276",
"REACTOME:R-BTA-6791226",
"REACTOME:R-BTA-72649",
"REACTOME:R-BTA-72689",
"REACTOME:R-BTA-72695",
"REACTOME:R-BTA-72702",
"REACTOME:R-BTA-72706",
"REACTOME:R-BTA-975956",
"REACTOME:R-BTA-9759... | 195 | [
"1ffk",
"1jj2",
"1k73",
"1k8a",
"1k9m",
"1kc8",
"1kd1",
"1kqs",
"1m1g",
"1m1h",
"1m1k",
"1m90",
"1ml5",
"1n8r",
"1nji",
"1nkw",
"1npp",
"1npr",
"1nwx",
"1nwy",
"1nz9",
"1q7y",
"1q81",
"1q82",
"1q86",
"1qvf",
"1qvg",
"1s72",
"1sm1",
"1vq4",
"1vq5",
"1vq6"... | 2,319 | [
"PUB00005458"
] | [
"8987397"
] | [
"KOW: a novel motif linking a bacterial transcription factor with ribosomal proteins."
] | [
1996
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
2043,
43419,
27559,
25,
858
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
46,
6,
11,
6,
2,
35,
15,
4,
39,
36,
8,
8,
201
] | 13 | true | Domain | KOW | KOW | KOW | 1 |
IPR005825 | 5,825 | Large ribosomal subunit protein uL24, conserved site | Ribosomal_uL24_CS | Conserved_site | 29,711 | false | false | This entry represents a conserved site found in the large ribosomal subunit protein uL24 family. Ribosomal protein uL24 is one of the proteins from the large ribosomal subunit. uL24 belongs to a family of ribosomal proteins which, on the basis of sequence similarities, groups: Eubacterial uL24. Plant chloroplast uL24 (... | [
"GO:0003735",
"GO:0006412",
"GO:0005840"
] | [
"structural constituent of ribosome",
"translation",
"ribosome"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PROSITE"
] | [
"PS01108"
] | [
"RIBOSOMAL_L24"
] | [
29711
] | 1 | [
"PROSITEDOC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACT... | [
"PDOC00852",
"R-BTA-156827",
"R-BTA-1799339",
"R-BTA-5389840",
"R-BTA-5419276",
"R-BTA-6791226",
"R-BTA-72689",
"R-BTA-72706",
"R-BTA-975956",
"R-BTA-975957",
"R-BTA-9937383",
"R-CEL-156827",
"R-CEL-1799339",
"R-CEL-5389840",
"R-CEL-5419276",
"R-CEL-72689",
"R-CEL-72706",
"R-CEL-97... | [
"PROSITEDOC:PDOC00852",
"REACTOME:R-BTA-156827",
"REACTOME:R-BTA-1799339",
"REACTOME:R-BTA-5389840",
"REACTOME:R-BTA-5419276",
"REACTOME:R-BTA-6791226",
"REACTOME:R-BTA-72689",
"REACTOME:R-BTA-72706",
"REACTOME:R-BTA-975956",
"REACTOME:R-BTA-975957",
"REACTOME:R-BTA-9937383",
"REACTOME:R-CEL-1... | 80 | [
"1ffk",
"1jj2",
"1k73",
"1k8a",
"1k9m",
"1kc8",
"1kd1",
"1kqs",
"1m1k",
"1m90",
"1ml5",
"1n8r",
"1nji",
"1nkw",
"1nwx",
"1nwy",
"1q7y",
"1q81",
"1q82",
"1q86",
"1qvf",
"1qvg",
"1s72",
"1sm1",
"1vq4",
"1vq5",
"1vq6",
"1vq7",
"1vq8",
"1vq9",
"1vqk",
"1vql"... | 1,872 | [
"PUB00004463",
"PUB00007068",
"PUB00007069",
"PUB00007070"
] | [
"7899076",
"11297922",
"11290319",
"11114498"
] | [
"Novel protein families in archaean genomes.",
"Atomic structures at last: the ribosome in 2000.",
"The ribosome in focus.",
"The end of the beginning: structural studies of ribosomal proteins."
] | [
1995,
2001,
2001,
2000
] | 4 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"unclassified sequences"
] | [
851,
19596,
16,
8932,
316
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (s... | [
20,
3,
2,
2,
1,
11,
5,
17,
13,
3,
1,
57
] | 12 | true | Conserved_site | Large ribosomal subunit protein uL24, conserved site | Large ribosomal subunit protein uL24, conserved site | Ribosomal_uL24_CS | 9 |
IPR005826 | 5,826 | Potassium channel, voltage dependent, Kv2.2 | K_chnl_volt-dep_Kv2.2 | Family | 584 | false | false | Potassium channels are the most diverse group of the ion channel family [ , ]. They are important in shaping the action potential, and in neuronal excitability and plasticity [ ]. The potassium channel family is composed of several functionally distinct isoforms, which can be broadly separated into 2 groups [ ]: the pr... | [
"GO:0005249",
"GO:0006813",
"GO:0008076"
] | [
"voltage-gated potassium channel activity",
"potassium ion transport",
"voltage-gated potassium channel complex"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PRINTS"
] | [
"PR01515"
] | [
"KV22CHANNEL"
] | [
584
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-1296072",
"R-HSA-1296072",
"R-MMU-1296072",
"R-RNO-1296072"
] | [
"REACTOME:R-BTA-1296072",
"REACTOME:R-HSA-1296072",
"REACTOME:R-MMU-1296072",
"REACTOME:R-RNO-1296072"
] | 4 | [] | 0 | [
"PUB00001055",
"PUB00001622",
"PUB00002771",
"PUB00004011",
"PUB00004020",
"PUB00006577",
"PUB00008322",
"PUB00009378",
"PUB00009391",
"PUB00036045"
] | [
"1772658",
"1879548",
"1373731",
"2448635",
"2451788",
"2555158",
"9305895",
"11178249",
"10712896",
"15950285"
] | [
"The molecular biology of K+ channels.",
"Shaw-like rat brain potassium channel cDNA's with divergent 3' ends.",
"Cloning, functional expression, and regulation of two K+ channels in human T lymphocytes.",
"Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Droso... | [
1991,
1991,
1992,
1988,
1988,
1989,
1997,
2000,
2000,
2005
] | 10 | [
"IPR003973"
] | [] | 1 | 0 | 1 | [
"Gnathostomata"
] | [
584
] | 1 | [
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
3
] | 3 | true | Family | Potassium channel, voltage dependent, Kv2.2 | Potassium channel, voltage dependent, Kv2.2 | K_chnl_volt-dep_Kv2.2 | 8 |
IPR005827 | 5,827 | Potassium channel, voltage dependent, KCNQ1 | K_chnl_volt-dep_KCQN1 | Family | 1,170 | false | false | Potassium channels are the most diverse group of the ion channel family [ , ]. They are important in shaping the action potential, and in neuronal excitability and plasticity [ ]. The potassium channel family is composed of several functionally distinct isoforms, which can be broadly separated into 2 groups [ ]: the pr... | [
"GO:0005249",
"GO:0006813",
"GO:0008076"
] | [
"voltage-gated potassium channel activity",
"potassium ion transport",
"voltage-gated potassium channel complex"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PRINTS"
] | [
"PR01460"
] | [
"KCNQ1CHANNEL"
] | [
1170
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-1296072",
"R-HSA-5576890",
"R-HSA-5576893",
"R-MMU-1296072",
"R-MMU-5576890",
"R-MMU-5576893",
"R-RNO-1296072",
"R-RNO-5576890",
"R-RNO-5576893"
] | [
"REACTOME:R-HSA-1296072",
"REACTOME:R-HSA-5576890",
"REACTOME:R-HSA-5576893",
"REACTOME:R-MMU-1296072",
"REACTOME:R-MMU-5576890",
"REACTOME:R-MMU-5576893",
"REACTOME:R-RNO-1296072",
"REACTOME:R-RNO-5576890",
"REACTOME:R-RNO-5576893"
] | 9 | [
"3bj4",
"5vms",
"6uzz",
"6v00",
"6v01",
"7tci",
"7tcp",
"7xni",
"7xnk",
"7xnl",
"7xnn",
"8sik",
"8sim",
"8sin",
"9my3",
"9my4",
"9u7f",
"9uc8",
"9vec",
"9vei",
"9ven",
"9veo",
"9wd8"
] | 23 | [
"PUB00001055",
"PUB00001622",
"PUB00002771",
"PUB00004011",
"PUB00004020",
"PUB00006577",
"PUB00008295",
"PUB00008296",
"PUB00008297",
"PUB00008986",
"PUB00008987",
"PUB00009378",
"PUB00095240"
] | [
"1772658",
"1879548",
"1373731",
"2448635",
"2451788",
"2555158",
"10838601",
"8528244",
"9430594",
"8900283",
"9020846",
"11178249",
"25037568"
] | [
"The molecular biology of K+ channels.",
"Shaw-like rat brain potassium channel cDNA's with divergent 3' ends.",
"Cloning, functional expression, and regulation of two K+ channels in human T lymphocytes.",
"Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Droso... | [
1991,
1991,
1992,
1988,
1988,
1989,
2000,
1996,
1998,
1996,
1997,
2000,
2014
] | 13 | [
"IPR003937"
] | [] | 1 | 0 | 1 | [
"Bilateria"
] | [
1170
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
19,
7,
5,
10
] | 4 | true | Family | Potassium channel, voltage dependent, KCNQ1 | Potassium channel, voltage dependent, KCNQ1 | K_chnl_volt-dep_KCQN1 | 8 |
IPR005828 | 5,828 | Major facilitator, sugar transporter-like | MFS_sugar_transport-like | Family | 342,381 | false | false | This entry represents a subfamily of the major facilitator superfamily. Members in this family include sugar transporters, which are responsible for the binding and transport of various carbohydrates, organic alcohols, and acids in a wide range of prokaryotic and eukaryotic organisms [ ]. Most but not all members of th... | [
"GO:0022857",
"GO:0055085",
"GO:0016020"
] | [
"transmembrane transporter activity",
"transmembrane transport",
"membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PFAM"
] | [
"PF00083"
] | [
"Sugar_tr"
] | [
342381
] | 1 | [
"GP",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
... | [
"GenProp0457",
"R-BTA-112311",
"R-BTA-181430",
"R-BTA-189200",
"R-BTA-196836",
"R-BTA-2161517",
"R-BTA-422356",
"R-BTA-442660",
"R-BTA-549127",
"R-BTA-5653890",
"R-BTA-6798695",
"R-BTA-8981373",
"R-BTA-917937",
"R-BTA-9793528",
"R-CEL-112311",
"R-CEL-181430",
"R-CEL-189200",
"R-CEL... | [
"GP:GenProp0457",
"REACTOME:R-BTA-112311",
"REACTOME:R-BTA-181430",
"REACTOME:R-BTA-189200",
"REACTOME:R-BTA-196836",
"REACTOME:R-BTA-2161517",
"REACTOME:R-BTA-422356",
"REACTOME:R-BTA-442660",
"REACTOME:R-BTA-549127",
"REACTOME:R-BTA-5653890",
"REACTOME:R-BTA-6798695",
"REACTOME:R-BTA-8981373... | 150 | [
"4gby",
"4gbz",
"4gc0",
"4ja3",
"4ja4",
"4lds",
"4pyp",
"4qiq",
"4yb9",
"4ybq",
"4zw9",
"4zwb",
"4zwc",
"5c65",
"5eqg",
"5eqh",
"5eqi",
"6h7d",
"6m20",
"6m2l",
"6n3i",
"6rw3",
"6tha",
"7aaq",
"7aar",
"7crz",
"7sp5",
"7sps",
"7spt",
"7wsm",
"7wsn",
"8bvr"... | 125 | [
"PUB00005096",
"PUB00007278",
"PUB00009720",
"PUB00009721",
"PUB00075603"
] | [
"3839598",
"9529885",
"8987357",
"1970645",
"26098515"
] | [
"Sequence and structure of a human glucose transporter.",
"Major facilitator superfamily.",
"Proton-dependent multidrug efflux systems.",
"Homologous sugar transport proteins in Escherichia coli and their relatives in both prokaryotes and eukaryotes.",
"Structural Biology of the Major Facilitator Superfamil... | [
1985,
1998,
1996,
1990,
2015
] | 5 | [] | [
"IPR003663",
"IPR004736",
"IPR004738",
"IPR004749"
] | 0 | 4 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"Sym plasmid",
"Viruses",
"unclassified sequences"
] | [
1273,
77357,
263342,
1,
2,
406
] | 6 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
339,
63,
133,
121,
8,
166,
95,
41,
272,
155,
36,
15,
485
] | 13 | true | Family | Major facilitator, sugar transporter-like | Major facilitator, sugar transporter-like | MFS_sugar_transport-like | 7 |
IPR005829 | 5,829 | Sugar transporter, conserved site | Sugar_transporter_CS | Conserved_site | 375,703 | false | false | This entry represents two conserved sites. The first is centered on a G-R-[KR] motif. The second is based on a number of conserved residues which are located at the end of the fourth transmembrane segment and in the short loop region between the fourth and fifth segments. The sugar transporters belong to a superfamily ... | [
"GO:0022857",
"GO:0055085",
"GO:0016020"
] | [
"transmembrane transporter activity",
"transmembrane transport",
"membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"PROSITE",
"PROSITE"
] | [
"PS00216",
"PS00217"
] | [
"SUGAR_TRANSPORT_1",
"SUGAR_TRANSPORT_2"
] | [
267235,
218824
] | 2 | [
"PROSITEDOC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACT... | [
"PDOC00190",
"R-BTA-112311",
"R-BTA-181430",
"R-BTA-189200",
"R-BTA-196757",
"R-BTA-196836",
"R-BTA-2161517",
"R-BTA-422356",
"R-BTA-442660",
"R-BTA-549127",
"R-BTA-5653890",
"R-BTA-6798695",
"R-BTA-8981373",
"R-BTA-917937",
"R-BTA-9707616",
"R-BTA-9793528",
"R-CEL-112311",
"R-CEL-... | [
"PROSITEDOC:PDOC00190",
"REACTOME:R-BTA-112311",
"REACTOME:R-BTA-181430",
"REACTOME:R-BTA-189200",
"REACTOME:R-BTA-196757",
"REACTOME:R-BTA-196836",
"REACTOME:R-BTA-2161517",
"REACTOME:R-BTA-422356",
"REACTOME:R-BTA-442660",
"REACTOME:R-BTA-549127",
"REACTOME:R-BTA-5653890",
"REACTOME:R-BTA-67... | 142 | [
"4gby",
"4gbz",
"4gc0",
"4ja3",
"4ja4",
"4lds",
"4pyp",
"4qiq",
"4yb9",
"4ybq",
"4zow",
"4zp0",
"4zp2",
"4zw9",
"4zwb",
"4zwc",
"5c65",
"5eqg",
"5eqh",
"5eqi",
"6euq",
"6gv1",
"6h7d",
"6m20",
"6m2l",
"6n3i",
"6oom",
"6oop",
"6ooq",
"6rw3",
"6tha",
"6vrz"... | 100 | [
"PUB00002464",
"PUB00003999",
"PUB00005096"
] | [
"3170580",
"3543693",
"3839598"
] | [
"Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues.",
"Mammalian and bacterial sugar transport proteins are homologous.",
"Sequence and structure of a human glucose transporter."
] | [
1988,
1987,
1985
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"plasmids",
"unclassified sequences"
] | [
2569,
175194,
196855,
2,
6,
1077
] | 6 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
276,
32,
84,
69,
13,
117,
68,
36,
186,
125,
36,
17,
340
] | 13 | true | Conserved_site | Sugar transporter, conserved site | Sugar transporter, conserved site | Sugar_transporter_CS | 3 |
IPR005830 | 5,830 | Aerolysin | Aerolysn | Family | 415 | false | false | Aerolysin [ ] is a cytolytic toxin exported by Aeromonas hydrophila, a Gram-negative bacterium associated with diarrhoeal diseases and deep wound infections [ ]. The mature toxin binds to eukaryotic cells and aggregates to form holes (approximately 3 nm in diameter) leading to the destruction of the membrane permeabili... | [
"GO:0005576"
] | [
"extracellular region"
] | [
"cellular_component"
] | 1 | [
"PRINTS"
] | [
"PR00754"
] | [
"AEROLYSIN"
] | [
415
] | 1 | [] | [] | [] | 0 | [
"1pre",
"1z52",
"3c0m",
"3c0n",
"3c0o",
"3g4n",
"3g4o",
"5jzh",
"5jzt",
"5jzw",
"9fm6",
"9fml",
"9fmx",
"9fnp",
"9fnq",
"9gxj"
] | 16 | [
"PUB00002061",
"PUB00004166"
] | [
"3584074",
"7510043"
] | [
"Nucleotide sequence of the gene for the hole-forming toxin aerolysin of Aeromonas hydrophila.",
"Structure of the Aeromonas toxin proaerolysin in its water-soluble and membrane-channel states."
] | [
1987,
1994
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eumetazoa",
"uncultured microorganism"
] | [
398,
16,
1
] | 3 | [] | [] | 0 | true | Family | Aerolysin | Aerolysin | Aerolysn | 1 |
IPR005831 | 5,831 | Aerolysin/haemolysin toxin, conserved site | Aerolysin/haemolysin_CS | Conserved_site | 173 | false | false | Aerolysin is a cytolytic toxin exported by the Gram-negative Aeromonas bacteria [ ]. The mature toxin binds to eukaryotic cells and aggregates to form holes (approximately 3 nm in diameter) leading to the destruction of the membrane permeability barrier and osmotic lysis. Staphylococcus aureus also exports a cytotoxin,... | [
"GO:0005576"
] | [
"extracellular region"
] | [
"cellular_component"
] | 1 | [
"PROSITE"
] | [
"PS00274"
] | [
"AEROLYSIN"
] | [
173
] | 1 | [
"PROSITEDOC",
"REACTOME",
"REACTOME"
] | [
"PDOC00247",
"R-HSA-844456",
"R-HSA-9660826"
] | [
"PROSITEDOC:PDOC00247",
"REACTOME:R-HSA-844456",
"REACTOME:R-HSA-9660826"
] | 3 | [
"1pre",
"1z52",
"3anz",
"3c0m",
"3c0n",
"3c0o",
"3g4n",
"3g4o",
"3m2l",
"3m3r",
"3m4d",
"3m4e",
"4idj",
"4p24",
"4u6v",
"4yhd",
"5jzh",
"5jzt",
"5jzw",
"6u3t",
"6u49",
"6u4p",
"7ahl",
"7o1q",
"8jx2",
"8jx3",
"9fm6",
"9fml",
"9fmx",
"9fnp",
"9fnq",
"9gxj"... | 40 | [
"PUB00067871"
] | [
"8845373"
] | [
"Protonation of histidine-132 promotes oligomerization of the channel-forming toxin aerolysin."
] | [
1995
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Penicillium daleae",
"uncultured microorganism"
] | [
171,
1,
1
] | 3 | [] | [] | 0 | true | Conserved_site | Aerolysin/haemolysin toxin, conserved site | Aerolysin/haemolysin toxin, conserved site | Aerolysin/haemolysin_CS | 3 |
IPR005835 | 5,835 | Nucleotidyl transferase domain | NTP_transferase_dom | Domain | 163,001 | false | false | Nucleotidyl transferases transfer nucleotides from one compound to another. This domain is found in a number of enzymes that transfer nucleotides onto phosphosugars [ ]. | [
"GO:0009058"
] | [
"biosynthetic process"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF00483"
] | [
"NTP_transferase"
] | [
163001
] | 1 | [
"EC",
"GP",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.7.7",
"GenProp0724",
"R-CEL-446205",
"R-CEL-72731",
"R-DDI-446205",
"R-DDI-72731",
"R-DME-446205",
"R-DRE-446205",
"R-HSA-446205",
"R-HSA-72731",
"R-MMU-446205",
"R-RNO-446205",
"R-RNO-72731",
"R-SCE-72731",
"R-SPO-446205",
"R-SPO-72731",
"R-XTR-446205"
] | [
"EC:2.7.7",
"GP:GenProp0724",
"REACTOME:R-CEL-446205",
"REACTOME:R-CEL-72731",
"REACTOME:R-DDI-446205",
"REACTOME:R-DDI-72731",
"REACTOME:R-DME-446205",
"REACTOME:R-DRE-446205",
"REACTOME:R-HSA-446205",
"REACTOME:R-HSA-72731",
"REACTOME:R-MMU-446205",
"REACTOME:R-RNO-446205",
"REACTOME:R-RNO... | 17 | [
"1fxo",
"1fzw",
"1g0r",
"1g1l",
"1g23",
"1g2v",
"1g3l",
"1g95",
"1g97",
"1h5r",
"1h5s",
"1h5t",
"1hm0",
"1hm8",
"1hm9",
"1iim",
"1iin",
"1jyk",
"1jyl",
"1lvw",
"1mc3",
"1mp3",
"1mp4",
"1mp5",
"1tzf",
"1wvc",
"1yp2",
"1yp3",
"1yp4",
"2cu2",
"2e3d",
"2ggo"... | 179 | [
"PUB00000676"
] | [
"9507048"
] | [
"Domain organisation in phosphomannose isomerases (types I and II)."
] | [
1998
] | 1 | [] | [
"IPR035543",
"IPR045233",
"IPR049577"
] | 0 | 3 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
4981,
132614,
22344,
169,
2893
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
63,
4,
19,
11,
6,
20,
15,
4,
31,
10,
2,
4,
141
] | 13 | true | Domain | Nucleotidyl transferase domain | Nucleotidyl transferase domain | NTP_transferase_dom | 2 |
IPR005836 | 5,836 | ADP-glucose pyrophosphorylase, conserved site | ADP_Glu_pyroP_CS | Conserved_site | 20,220 | false | false | ADP-glucose pyrophosphorylase (glucose-1-phosphate adenylyltransferase) [ ] ( ) catalyzes a very important step in the biosynthesis of alpha 1,4-glucans (glycogen or starch) in bacteria and plants: synthesis of the activated glucosyl donor, ADP-glucose, from glucose-1-phosphate and ATP. ADP-glucose pyrophosphorylase is... | [
"GO:0008878",
"GO:0005978"
] | [
"glucose-1-phosphate adenylyltransferase activity",
"glycogen biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PROSITE",
"PROSITE",
"PROSITE"
] | [
"PS00808",
"PS00809",
"PS00810"
] | [
"ADP_GLC_PYROPHOSPH_1",
"ADP_GLC_PYROPHOSPH_2",
"ADP_GLC_PYROPHOSPH_3"
] | [
16452,
18849,
16197
] | 3 | [
"EC",
"METACYC",
"METACYC",
"PROSITEDOC"
] | [
"2.7.7.27",
"PWY-622",
"PWY-7902",
"PDOC00638"
] | [
"EC:2.7.7.27",
"METACYC:PWY-622",
"METACYC:PWY-7902",
"PROSITEDOC:PDOC00638"
] | 4 | [
"1yp2",
"1yp3",
"1yp4",
"3brk",
"5l6s",
"5l6v",
"5mni",
"5w5r",
"5w5t",
"5w6j",
"6r8b",
"6r8u",
"6shj",
"6shn",
"6shq",
"6si8",
"6v96",
"6v99",
"6v9a",
"6vr0"
] | 20 | [
"PUB00004547"
] | [
"1657244"
] | [
"Comparison of the primary sequences of two potato tuber ADP-glucose pyrophosphorylase subunits."
] | [
1991
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Bathycoccus sp. RCC716 virus 1",
"Eukaryota",
"Methanomicrobia",
"unclassified sequences"
] | [
15687,
1,
4341,
2,
189
] | 5 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
28,
1,
14,
82
] | 4 | true | Conserved_site | ADP-glucose pyrophosphorylase, conserved site | ADP-glucose pyrophosphorylase, conserved site | ADP_Glu_pyroP_CS | 3 |
IPR005837 | 5,837 | Flagellar transport protein FliP | FliP | Family | 13,247 | false | false | This model describes bacterial flagellar biogenesis protein fliP, which is one of the genes within the motility locus on the bacterial chromosome that is involved in structure and function of bacterial flagellum. It was demonstrated that mutants in fliP locus were non-flagellated and non-motile, while revertants were f... | [
"GO:0009306",
"GO:0016020"
] | [
"protein secretion",
"membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PRINTS",
"NCBIFAM"
] | [
"PR00951",
"TIGR01103"
] | [
"FLGBIOSNFLIP",
"fliP"
] | [
13004,
12903
] | 2 | [
"GP"
] | [
"GenProp0879"
] | [
"GP:GenProp0879"
] | 1 | [
"6f2d",
"6r69",
"6s3l",
"6s3r",
"6s3s",
"7bin",
"7cg4",
"7cgo",
"7e80",
"7nvg",
"8wk3",
"8wkk",
"8wkq",
"8wl2",
"8wlh",
"8wln",
"8wlq",
"8wlt",
"8wo5",
"8woe",
"8z5s",
"8z5u",
"8z5x",
"8z60",
"9k29"
] | 25 | [
"PUB00002241"
] | [
"8282695"
] | [
"Molecular characterization, nucleotide sequence, and expression of the fliO, fliP, fliQ, and fliR genes of Escherichia coli."
] | [
1994
] | 1 | [
"IPR005838"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
13083,
17,
147
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Flagellar transport protein FliP | Flagellar transport protein FliP | FliP | 9 |
IPR005838 | 5,838 | Type III secretion system inner membrane P protein | T3SS_IM_P | Family | 17,016 | false | false | Secretion of virulence factors in Gram-negative bacteria involves transportation of the protein across two membranes to reach the cell exterior [ ]. There have been four secretion systems described in animal enteropathogens such as Salmonella and Yersinia, with further sequence similarities in plant pathogens like Rals... | [
"GO:0009306",
"GO:0016020"
] | [
"protein secretion",
"membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"NCBIFAM",
"PFAM",
"PRINTS",
"PROSITE",
"PROSITE",
"PANTHER"
] | [
"NF009438",
"PF00813",
"PR01302",
"PS01060",
"PS01061",
"PTHR30587"
] | [
"PRK12797.1",
"FliP",
"TYPE3IMPPROT",
"FLIP_1",
"FLIP_2",
""
] | [
15980,
16974,
16872,
12371,
15273,
16947
] | 6 | [
"PROSITEDOC"
] | [
"PDOC00812"
] | [
"PROSITEDOC:PDOC00812"
] | 1 | [
"5h72",
"6f2d",
"6pem",
"6pep",
"6q14",
"6q15",
"6q16",
"6r69",
"6r6b",
"6rwy",
"6s3l",
"6s3r",
"6s3s",
"7agx",
"7ah9",
"7ahi",
"7bin",
"7cg4",
"7cgo",
"7e80",
"7nvg",
"8axk",
"8wk3",
"8wkk",
"8wkq",
"8wl2",
"8wlh",
"8wln",
"8wlq",
"8wlt",
"8wo5",
"8woe"... | 37 | [
"PUB00003585",
"PUB00007583",
"PUB00007897",
"PUB00007898"
] | [
"9618447",
"10564516",
"8969244",
"10334981"
] | [
"Type III protein secretion systems in bacterial pathogens of animals and plants.",
"Flagellar proteins and type III-exported virulence factors are the predominant proteins secreted into the culture media of Salmonella typhimurium.",
"Molecular mechanisms of bacterial virulence: type III secretion and pathogeni... | [
1998,
1999,
1996,
1999
] | 4 | [] | [
"IPR005773",
"IPR005837"
] | 0 | 2 | 0 | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
16815,
28,
173
] | 3 | [
"Escherichia coli (strain K12)",
"Zea mays"
] | [
1,
1
] | 2 | true | Family | Type III secretion system inner membrane P protein | Type III secretion system inner membrane P protein | T3SS_IM_P | 7 |
IPR005839 | 5,839 | Methylthiotransferase | Methylthiotransferase | Family | 57,050 | false | false | The methylthiotransferase (MTTase) or miaB-like family is named after the (dimethylallyl)adenosine tRNA MTTase miaB protein, which catalyses a C-H to C-S bond conversion in the methylthiolation of tRNA. A related bacterial enzyme RimO performs a similar methylthiolation, but on a protein substrate. RimO acts on the rib... | [
"GO:0016740",
"GO:0051539",
"GO:0006400"
] | [
"transferase activity",
"4 iron, 4 sulfur cluster binding",
"tRNA modification"
] | [
"molecular_function",
"molecular_function",
"biological_process"
] | 3 | [
"SFLD",
"NCBIFAM"
] | [
"SFLDG01061",
"TIGR00089"
] | [
"methylthiotransferase",
""
] | [
50624,
56160
] | 2 | [
"EC",
"PROSITEDOC",
"REACTOME"
] | [
"2.8.4",
"PDOC00984",
"R-HSA-6782315"
] | [
"EC:2.8.4",
"PROSITEDOC:PDOC00984",
"REACTOME:R-HSA-6782315"
] | 3 | [
"2qgq",
"4jc0",
"7mjv",
"7mjw",
"7mjx",
"7mjy",
"7mjz",
"9p0p"
] | 8 | [
"PUB00009728",
"PUB00010539",
"PUB00046148",
"PUB00052321",
"PUB00083160"
] | [
"11882645",
"11222759",
"18252828",
"15289575",
"20584901"
] | [
"Enzymatic modification of tRNAs: MiaB is an iron-sulfur protein.",
"Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods.",
"RimO, a MiaB-like enzyme, met... | [
2002,
2001,
2008,
2004,
2010
] | 5 | [] | [
"IPR005840",
"IPR006463",
"IPR006466",
"IPR006467"
] | 0 | 4 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
873,
49815,
5312,
3,
1047
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Zea mays"
] | [
8,
1,
4,
2,
2,
5,
2,
5,
11,
7
] | 10 | true | Family | Methylthiotransferase | Methylthiotransferase | Methylthiotransferase | 9 |
IPR005840 | 5,840 | Ribosomal protein uS12 methylthiotransferase RimO | Ribosomal_uS12_MeSTrfase_RimO | Family | 17,808 | false | false | In many bacterial species ribosmal protein uS12 is posttranslationally modified by the methylthiolation of the aspartate residue at position 88. The enzyme responsible for this modification is RimO, a radical S-adenoslymethionine protein [ ]. | [
"GO:0016740",
"GO:0051539",
"GO:0018339",
"GO:0005737"
] | [
"transferase activity",
"4 iron, 4 sulfur cluster binding",
"peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid",
"cytoplasm"
] | [
"molecular_function",
"molecular_function",
"biological_process",
"cellular_component"
] | 4 | [
"HAMAP",
"PANTHER",
"SFLD",
"NCBIFAM"
] | [
"MF_01865",
"PTHR43837",
"SFLDF00274",
"TIGR01125"
] | [
"MTTase_RimO",
"",
"ribosomal_protein_S12_methylth",
""
] | [
16293,
17807,
15736,
16201
] | 4 | [
"EC"
] | [
"2.8.4.4"
] | [
"EC:2.8.4.4"
] | 1 | [
"2qgq",
"4jc0"
] | 2 | [
"PUB00046148"
] | [
"18252828"
] | [
"RimO, a MiaB-like enzyme, methylthiolates the universally conserved Asp88 residue of ribosomal protein S12 in Escherichia coli."
] | [
2008
] | 1 | [
"IPR005839"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"Siphoviridae sp. ctj8j9",
"unclassified sequences"
] | [
17062,
166,
1,
579
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Ribosomal protein uS12 methylthiotransferase RimO | Ribosomal protein uS12 methylthiotransferase RimO | Ribosomal_uS12_MeSTrfase_RimO | 4 |
IPR005841 | 5,841 | Alpha-D-phosphohexomutase superfamily | Alpha-D-phosphohexomutase_SF | Family | 72,376 | false | false | The alpha-D-phosphohexomutase superfamily is composed of four related enzymes, each of which catalyses a phosphoryl transfer on their sugar substrates: phosphoglucomutase (PGM), phosphoglucomutase/phosphomannomutase (PGM/PMM), phosphoglucosamine mutase (PNGM), and phosphoacetylglucosamine mutase (PAGM) [ ]. PGM ( ) con... | [
"GO:0016868",
"GO:0005975"
] | [
"intramolecular phosphotransferase activity",
"carbohydrate metabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PRINTS"
] | [
"PR00509"
] | [
"PGMPMM"
] | [
72376
] | 1 | [
"EC",
"EC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTO... | [
"5.4.2",
"5.4.2.10",
"PWY-6749",
"R-DDI-3322077",
"R-DDI-6798695",
"R-DDI-70171",
"R-DDI-70221",
"R-DDI-70370",
"R-DDI-71336",
"R-DME-3322077",
"R-DME-6798695",
"R-DME-70221",
"R-DME-70370",
"R-HSA-3322077",
"R-HSA-5609974",
"R-HSA-6798695",
"R-HSA-70221",
"R-HSA-70370",
"R-HSA-7... | [
"EC:5.4.2",
"EC:5.4.2.10",
"METACYC:PWY-6749",
"REACTOME:R-DDI-3322077",
"REACTOME:R-DDI-6798695",
"REACTOME:R-DDI-70171",
"REACTOME:R-DDI-70221",
"REACTOME:R-DDI-70370",
"REACTOME:R-DDI-71336",
"REACTOME:R-DME-3322077",
"REACTOME:R-DME-6798695",
"REACTOME:R-DME-70221",
"REACTOME:R-DME-70370... | 37 | [
"1c47",
"1c4g",
"1jdy",
"1k2y",
"1k35",
"1kfi",
"1kfq",
"1lxt",
"1p5d",
"1p5g",
"1pcj",
"1pcm",
"1tuo",
"1vkl",
"1wqa",
"2f7l",
"2fkf",
"2fkm",
"2h4l",
"2h5a",
"3bkq",
"3c04",
"3i3w",
"3pdk",
"3pmg",
"3rsm",
"3uw2",
"4il8",
"4mrq",
"4qg5",
"5bmn",
"5bmp"... | 86 | [
"PUB00022429",
"PUB00037156",
"PUB00040705",
"PUB00042561",
"PUB00042562",
"PUB00042563",
"PUB00042564"
] | [
"14725765",
"15299905",
"16595672",
"10506283",
"10913078",
"11004509",
"15238632"
] | [
"Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.",
"Structure of rabbit muscle phosphoglucomutase refined at 2.4 A resolution.",
"The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.",
"Functional divers... | [
2004,
1997,
2006,
1999,
2000,
2000,
2004
] | 7 | [] | [
"IPR006352",
"IPR023666",
"IPR024086"
] | 0 | 3 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
2395,
57797,
10845,
5,
1334
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
30,
3,
6,
5,
2,
9,
10,
1,
14,
14,
2,
2,
37
] | 13 | true | Family | Alpha-D-phosphohexomutase superfamily | Alpha-D-phosphohexomutase superfamily | Alpha-D-phosphohexomutase_SF | 5 |
IPR005843 | 5,843 | Alpha-D-phosphohexomutase, C-terminal | A-D-PHexomutase_C | Domain | 70,841 | false | false | This entry represents the C-terminal domain alpha-D-phosphohexomutase enzymes. The alpha-D-phosphohexomutase superfamily is composed of four related enzymes, each of which catalyses a phosphoryl transfer on their sugar substrates: phosphoglucomutase (PGM), phosphoglucomutase/phosphomannomutase (PGM/PMM), phosphoglucosa... | [
"GO:0016868"
] | [
"intramolecular phosphotransferase activity"
] | [
"molecular_function"
] | 1 | [
"PFAM"
] | [
"PF00408"
] | [
"PGM_PMM_IV"
] | [
70841
] | 1 | [
"EC",
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"5.4.2",
"5.4.2.10",
"GenProp1017",
"GenProp1222",
"GenProp1259",
"GenProp1639",
"GenProp1661",
"PWY-6749",
"R-HSA-446210",
"R-MMU-446210",
"R-SCE-446210",
"R-SPO-446210",
"R-SSC-446210"
] | [
"EC:5.4.2",
"EC:5.4.2.10",
"GP:GenProp1017",
"GP:GenProp1222",
"GP:GenProp1259",
"GP:GenProp1639",
"GP:GenProp1661",
"METACYC:PWY-6749",
"REACTOME:R-HSA-446210",
"REACTOME:R-MMU-446210",
"REACTOME:R-SCE-446210",
"REACTOME:R-SPO-446210",
"REACTOME:R-SSC-446210"
] | 13 | [
"1k2y",
"1k35",
"1p5d",
"1p5g",
"1pcj",
"1pcm",
"1tuo",
"1wjw",
"1wqa",
"2dka",
"2dkc",
"2dkd",
"2f7l",
"2fkf",
"2fkm",
"2fuv",
"2h4l",
"2h5a",
"2z0f",
"3bkq",
"3c04",
"3i3w",
"3na5",
"3olp",
"3pdk",
"3rsm",
"3uw2",
"4bju",
"4hjh",
"4il8",
"4mrq",
"5bmn"... | 64 | [
"PUB00022429",
"PUB00037156",
"PUB00040705",
"PUB00042561",
"PUB00042562",
"PUB00042563",
"PUB00042564"
] | [
"14725765",
"15299905",
"16595672",
"10506283",
"10913078",
"11004509",
"15238632"
] | [
"Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.",
"Structure of rabbit muscle phosphoglucomutase refined at 2.4 A resolution.",
"The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.",
"Functional divers... | [
2004,
1997,
2006,
1999,
2000,
2000,
2004
] | 7 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
2437,
61545,
5423,
5,
1431
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
3,
1,
1,
1,
3,
14,
6,
1,
1,
6,
1,
2,
4
] | 13 | true | Domain | Alpha-D-phosphohexomutase, C-terminal | Alpha-D-phosphohexomutase, C-terminal | A-D-PHexomutase_C | 4 |
IPR005844 | 5,844 | Alpha-D-phosphohexomutase, alpha/beta/alpha domain I | A-D-PHexomutase_a/b/a-I | Domain | 95,847 | false | false | This entry represents domain I found in alpha-D-phosphohexomutase enzymes. This domain has a 3-layer α/β/α topology. The alpha-D-phosphohexomutase superfamily is composed of four related enzymes, each of which catalyses a phosphoryl transfer on their sugar substrates: phosphoglucomutase (PGM), phosphoglucomutase/phosph... | [
"GO:0016868",
"GO:0005975"
] | [
"intramolecular phosphotransferase activity",
"carbohydrate metabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PFAM"
] | [
"PF02878"
] | [
"PGM_PMM_I"
] | [
95847
] | 1 | [
"EC",
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME... | [
"5.4.2",
"5.4.2.10",
"GenProp1017",
"GenProp1222",
"GenProp1259",
"GenProp1639",
"GenProp1661",
"PWY-6749",
"R-DDI-3322077",
"R-DDI-6798695",
"R-DDI-70171",
"R-DDI-70221",
"R-DDI-70370",
"R-DDI-71336",
"R-DME-3322077",
"R-DME-6798695",
"R-DME-70221",
"R-DME-70370",
"R-HSA-3322077... | [
"EC:5.4.2",
"EC:5.4.2.10",
"GP:GenProp1017",
"GP:GenProp1222",
"GP:GenProp1259",
"GP:GenProp1639",
"GP:GenProp1661",
"METACYC:PWY-6749",
"REACTOME:R-DDI-3322077",
"REACTOME:R-DDI-6798695",
"REACTOME:R-DDI-70171",
"REACTOME:R-DDI-70221",
"REACTOME:R-DDI-70370",
"REACTOME:R-DDI-71336",
"RE... | 52 | [
"1c47",
"1c4g",
"1jdy",
"1k2y",
"1k35",
"1kfi",
"1kfq",
"1lxt",
"1p5d",
"1p5g",
"1pcj",
"1pcm",
"1tuo",
"1vkl",
"1wqa",
"2dka",
"2dkc",
"2dkd",
"2f7l",
"2fkf",
"2fkm",
"2fuv",
"2h4l",
"2h5a",
"2z0f",
"3bkq",
"3c04",
"3i3w",
"3na5",
"3olp",
"3pdk",
"3pmg"... | 97 | [
"PUB00022429",
"PUB00037156",
"PUB00040705",
"PUB00042561",
"PUB00042562",
"PUB00042563",
"PUB00042564"
] | [
"14725765",
"15299905",
"16595672",
"10506283",
"10913078",
"11004509",
"15238632"
] | [
"Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.",
"Structure of rabbit muscle phosphoglucomutase refined at 2.4 A resolution.",
"The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.",
"Functional divers... | [
2004,
1997,
2006,
1999,
2000,
2000,
2004
] | 7 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
2530,
73120,
18628,
6,
1563
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
33,
4,
7,
9,
3,
31,
21,
2,
14,
21,
4,
4,
41
] | 13 | true | Domain | Alpha-D-phosphohexomutase, alpha/beta/alpha domain I | Alpha-D-phosphohexomutase, alpha/beta/alpha domain I | A-D-PHexomutase_a/b/a-I | 1 |
IPR005845 | 5,845 | Alpha-D-phosphohexomutase, alpha/beta/alpha domain II | A-D-PHexomutase_a/b/a-II | Domain | 89,029 | false | false | This entry represents domain II found in alpha-D-phosphohexomutase enzymes. This domain has a 3-layer α/β/α topology. The alpha-D-phosphohexomutase superfamily is composed of four related enzymes, each of which catalyses a phosphoryl transfer on their sugar substrates: phosphoglucomutase (PGM), phosphoglucomutase/phosp... | [
"GO:0005975"
] | [
"carbohydrate metabolic process"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF02879"
] | [
"PGM_PMM_II"
] | [
89029
] | 1 | [
"EC",
"EC",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"RE... | [
"5.4.2",
"5.4.2.10",
"GenProp1017",
"GenProp1259",
"GenProp1639",
"GenProp1661",
"PWY-6749",
"R-DDI-3322077",
"R-DDI-6798695",
"R-DDI-70171",
"R-DDI-70221",
"R-DDI-70370",
"R-DDI-71336",
"R-DME-3322077",
"R-DME-6798695",
"R-DME-70221",
"R-DME-70370",
"R-HSA-3322077",
"R-HSA-56099... | [
"EC:5.4.2",
"EC:5.4.2.10",
"GP:GenProp1017",
"GP:GenProp1259",
"GP:GenProp1639",
"GP:GenProp1661",
"METACYC:PWY-6749",
"REACTOME:R-DDI-3322077",
"REACTOME:R-DDI-6798695",
"REACTOME:R-DDI-70171",
"REACTOME:R-DDI-70221",
"REACTOME:R-DDI-70370",
"REACTOME:R-DDI-71336",
"REACTOME:R-DME-3322077... | 46 | [
"1c47",
"1c4g",
"1jdy",
"1k2y",
"1k35",
"1kfi",
"1kfq",
"1lxt",
"1p5d",
"1p5g",
"1pcj",
"1pcm",
"1tuo",
"1vkl",
"1wqa",
"2f7l",
"2fkf",
"2fkm",
"2fuv",
"2h4l",
"2h5a",
"2z0f",
"3bkq",
"3c04",
"3i3w",
"3na5",
"3olp",
"3pdk",
"3pmg",
"3rsm",
"3uw2",
"4hjh"... | 91 | [
"PUB00022429",
"PUB00037156",
"PUB00040705",
"PUB00042561",
"PUB00042562",
"PUB00042563",
"PUB00042564"
] | [
"14725765",
"15299905",
"16595672",
"10506283",
"10913078",
"11004509",
"15238632"
] | [
"Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.",
"Structure of rabbit muscle phosphoglucomutase refined at 2.4 A resolution.",
"The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.",
"Functional divers... | [
2004,
1997,
2006,
1999,
2000,
2000,
2004
] | 7 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
2458,
71750,
13325,
5,
1491
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
30,
3,
6,
9,
3,
10,
13,
1,
14,
18,
3,
2,
34
] | 13 | true | Domain | Alpha-D-phosphohexomutase, alpha/beta/alpha domain II | Alpha-D-phosphohexomutase, alpha/beta/alpha domain II | A-D-PHexomutase_a/b/a-II | 1 |
IPR005848 | 5,848 | Urease, alpha subunit | Urease_asu | Family | 15,827 | false | false | Urease (urea amidohydrolase, ) is a nickel-binding enzyme that catalyses the hydrolysis of urea to form ammonia and carbamate [ ]. It is mainly found in plant seeds, microorganisms and invertebrates. In plants, urease is a hexamer of identical chains, but the subunit composition of urease from different sources varies ... | [
"GO:0009039",
"GO:0016151"
] | [
"urease activity",
"nickel cation binding"
] | [
"molecular_function",
"molecular_function"
] | 2 | [
"HAMAP",
"NCBIFAM",
"PRINTS",
"NCBIFAM",
"CDD"
] | [
"MF_01953",
"NF009686",
"PR01752",
"TIGR01792",
"cd00375"
] | [
"Urease_alpha",
"PRK13207.1",
"UREASE",
"urease_alph",
"Urease_alpha"
] | [
14368,
15568,
15619,
13450,
12560
] | 5 | [
"EC",
"GP",
"METACYC",
"PROSITEDOC"
] | [
"3.5.1.5",
"GenProp0051",
"PWY-5704",
"PDOC00133"
] | [
"EC:3.5.1.5",
"GP:GenProp0051",
"METACYC:PWY-5704",
"PROSITEDOC:PDOC00133"
] | 4 | [
"1a5k",
"1a5l",
"1a5m",
"1a5n",
"1a5o",
"1e9y",
"1e9z",
"1ef2",
"1ejr",
"1ejs",
"1ejt",
"1eju",
"1ejv",
"1ejw",
"1ejx",
"1fwa",
"1fwb",
"1fwc",
"1fwd",
"1fwe",
"1fwf",
"1fwg",
"1fwh",
"1fwi",
"1fwj",
"1ie7",
"1kra",
"1krb",
"1krc",
"1s3t",
"1ubp",
"2kau"... | 84 | [
"PUB00001363",
"PUB00003605",
"PUB00005206",
"PUB00010725",
"PUB00018936",
"PUB00104861",
"PUB00104862",
"PUB00104864",
"PUB00104865",
"PUB00104866",
"PUB00104867",
"PUB00104868",
"PUB00104869"
] | [
"3402446",
"2651866",
"7754395",
"7565414",
"11373617",
"10913107",
"11101668",
"17101645",
"17578575",
"10075427",
"10639468",
"10844692",
"11500473"
] | [
"The structure of jack bean urease. The complete amino acid sequence, limited proteolysis and reactive cysteine residues.",
"Microbial ureases: significance, regulation, and molecular characterization.",
"The crystal structure of urease from Klebsiella aerogenes.",
"Molecular biology of microbial ureases.",
... | [
1988,
1989,
1995,
1995,
2001,
2000,
2000,
2007,
2007,
1999,
2000,
2000,
2001
] | 13 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
683,
11635,
2748,
761
] | 4 | [
"Arabidopsis thaliana",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
6,
2,
1,
1,
14
] | 5 | true | Family | Urease, alpha subunit | Urease, alpha subunit | Urease_asu | 3 |
IPR005850 | 5,850 | Galactose-1-phosphate uridyl transferase, C-terminal | GalP_Utransf_C | Domain | 16,403 | false | false | Galactose-1-phosphate uridyl transferase catalyses the conversion of UDP-glucose and alpha-D-galactose 1-phosphate to alpha-D-glucose 1-phosphate and UDP-galactose during galactose metabolism. The enzyme is present in prokaryotes and eukaryotes. Defects in GalT in humans is the cause of galactosemia, an inherited disor... | [
"GO:0008108",
"GO:0006012"
] | [
"UDP-glucose:hexose-1-phosphate uridylyltransferase activity",
"galactose metabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PFAM"
] | [
"PF02744"
] | [
"GalP_UDP_tr_C"
] | [
16403
] | 1 | [
"EC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.7.7.12",
"PWY-6317",
"PWY-6527",
"R-CEL-70370",
"R-DME-70370",
"R-HSA-5609978",
"R-HSA-70370",
"R-MMU-70370",
"R-RNO-70370"
] | [
"EC:2.7.7.12",
"METACYC:PWY-6317",
"METACYC:PWY-6527",
"REACTOME:R-CEL-70370",
"REACTOME:R-DME-70370",
"REACTOME:R-HSA-5609978",
"REACTOME:R-HSA-70370",
"REACTOME:R-MMU-70370",
"REACTOME:R-RNO-70370"
] | 9 | [
"1gup",
"1guq",
"1hxp",
"1hxq",
"1z84",
"1zwj",
"2h39",
"2q4h",
"2q4l",
"5in3",
"6gqd",
"6k5z",
"6k9z"
] | 13 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
86,
12417,
3649,
251
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
4,
1,
3,
2,
1,
7,
6,
1,
2,
4,
1,
1
] | 12 | true | Domain | Galactose-1-phosphate uridyl transferase, C-terminal | Galactose-1-phosphate uridyl transferase, C-terminal | GalP_Utransf_C | 5 |
IPR005852 | 5,852 | Phosphoglucomutase, alpha-D-glucose specific | PGM_a-D-Glc-sp | Family | 7,814 | false | false | Phosphoglucomutase, alpha-D-glucose phosphate-specific ( ) links the anaerobic or aerobic glycolysis of glucose-6-phosphate and glucose-1-phosphate produced by various glycan phosphorylases by catalysing the transfer of a phosphate group between C-1 and C-6 of glucose [ ]. The alpha-D-phosphohexomutases include several... | [
"GO:0004614",
"GO:0005975"
] | [
"phosphoglucomutase activity",
"carbohydrate metabolic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM",
"CDD"
] | [
"TIGR01132",
"cd05801"
] | [
"pgm",
"PGM_like3"
] | [
7774,
7460
] | 2 | [
"GP",
"GP",
"GP",
"GP"
] | [
"GenProp1247",
"GenProp1310",
"GenProp1412",
"GenProp1743"
] | [
"GP:GenProp1247",
"GP:GenProp1310",
"GP:GenProp1412",
"GP:GenProp1743"
] | 4 | [
"2fuv",
"2z0f",
"3na5",
"3olp"
] | 4 | [
"PUB00037156",
"PUB00042561",
"PUB00042564",
"PUB00080216"
] | [
"15299905",
"10506283",
"15238632",
"9549096"
] | [
"Structure of rabbit muscle phosphoglucomutase refined at 2.4 A resolution.",
"Functional diversity of the phosphoglucomutase superfamily: structural implications.",
"Evolutionary trace analysis of the alpha-D-phosphohexomutase superfamily.",
"A phylogenetic approach to the identification of phosphoglucomutas... | [
1997,
1999,
2004,
1998
] | 4 | [
"IPR045244"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Opisthokonta",
"metagenomes"
] | [
7781,
3,
30
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Phosphoglucomutase, alpha-D-glucose specific | Phosphoglucomutase, alpha-D-glucose specific | PGM_a-D-Glc-sp | 4 |
IPR005853 | 5,853 | Omega-agatoxin type II/III, conserved site | Omega-agatoxin_II/III_CS | Conserved_site | 18 | false | false | Spider venoms often contain many active peptides, such as neurotoxins, lectins, and enzyme inhibitors, which are important for both hunting and defence. Starting from a common ancestor these peptides have evolved into a diverse array of toxins with different structures and functions. These toxins contain contain a rela... | [] | [] | [] | 0 | [
"PROSITE"
] | [
"PS60023"
] | [
"OMEGA_AGA_II_III"
] | [
18
] | 1 | [
"PROSITEDOC"
] | [
"PDOC60023"
] | [
"PROSITEDOC:PDOC60023"
] | 1 | [] | 0 | [
"PUB00016620",
"PUB00033814",
"PUB00033815",
"PUB00033836"
] | [
"15225557",
"11086219",
"11711120",
"9683727"
] | [
"Toxins in anti-nociception and anti-inflammation.",
"Structure and pharmacology of spider venom neurotoxins.",
"Pharmacology and biochemistry of spider venoms.",
"omega-phonetoxin-IIA: a calcium channel blocker from the spider phoneutria nigriventer"
] | [
2004,
2000,
2002,
1998
] | 4 | [] | [] | 0 | 0 | null | [
"RTA clade"
] | [
18
] | 1 | [] | [] | 0 | true | Conserved_site | Omega-agatoxin type II/III, conserved site | Omega-agatoxin type II/III, conserved site | Omega-agatoxin_II/III_CS | 8 |
IPR005854 | 5,854 | Amidophosphoribosyltransferase | PurF | Family | 27,631 | false | false | This family contains sequences which are members of the MEROPS peptidase family C44 (glutamine phosphoribosylpyrophosphate amidotransferase precursor, clan PB(C)) and sequences which are classed as non-peptidase homologues. These are sequences either have been found experimentally to be without peptidase activity, or l... | [
"GO:0004044",
"GO:0009113"
] | [
"amidophosphoribosyltransferase activity",
"purine nucleobase biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"HAMAP",
"PIRSF",
"NCBIFAM"
] | [
"MF_01931",
"PIRSF000485",
"TIGR01134"
] | [
"PurF",
"Amd_phspho_trans",
"purF"
] | [
25944,
26478,
25942
] | 3 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.4.2.14",
"GenProp0110",
"GenProp1284",
"GenProp1628",
"GenProp1689",
"PWY-6121",
"PWY-6122",
"PWY-6277",
"R-DME-73817",
"R-GGA-419140",
"R-HSA-73817",
"R-MMU-73817",
"R-RNO-73817"
] | [
"EC:2.4.2.14",
"GP:GenProp0110",
"GP:GenProp1284",
"GP:GenProp1628",
"GP:GenProp1689",
"METACYC:PWY-6121",
"METACYC:PWY-6122",
"METACYC:PWY-6277",
"REACTOME:R-DME-73817",
"REACTOME:R-GGA-419140",
"REACTOME:R-HSA-73817",
"REACTOME:R-MMU-73817",
"REACTOME:R-RNO-73817"
] | 13 | [
"1ao0",
"1ecb",
"1ecc",
"1ecf",
"1ecg",
"1ecj",
"1gph",
"6czf",
"6lbp",
"6ott",
"8w7d"
] | 11 | [
"PUB00033234",
"PUB00085614"
] | [
"11290738",
"9914248"
] | [
"Feedback inhibition of amidophosphoribosyltransferase regulates the rate of cell growth via purine nucleotide, DNA, and protein syntheses.",
"Glutamine PRPP amidotransferase: snapshots of an enzyme in action."
] | [
2001,
1998
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Megaviricetes",
"unclassified sequences"
] | [
914,
22099,
4185,
3,
430
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",... | [
10,
1,
1,
6,
1,
3,
2,
1,
5,
3,
1,
1,
8
] | 13 | true | Family | Amidophosphoribosyltransferase | Amidophosphoribosyltransferase | PurF | 8 |
IPR005855 | 5,855 | Glucosamine-fructose-6-phosphate aminotransferase, isomerising | GFAT | Family | 33,396 | false | false | Glucosamine:fructose-6-phosphate aminotransferase (GFAT or GlmS, ) catalyses the formation of glucosamine 6-phosphate and is the first and rate-limiting enzyme of the hexosamine biosynthetic pathway. The final product of the hexosamine pathway, UDP-N-acetyl glucosamine, is an active precursor of numerous macromolecules... | [
"GO:0004360",
"GO:1901137"
] | [
"glutamine-fructose-6-phosphate transaminase (isomerizing) activity",
"carbohydrate derivative biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_00164",
"TIGR01135"
] | [
"GlmS",
"glmS"
] | [
27133,
33378
] | 2 | [
"EC",
"GP",
"GP",
"GP",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"2.6.1.16",
"GenProp0750",
"GenProp1222",
"GenProp1443",
"PWY-6749",
"PWY-8013",
"R-HSA-381038",
"R-HSA-4085023",
"R-HSA-446210",
"R-MMU-446210",
"R-RNO-446210"
] | [
"EC:2.6.1.16",
"GP:GenProp0750",
"GP:GenProp1222",
"GP:GenProp1443",
"METACYC:PWY-6749",
"METACYC:PWY-8013",
"REACTOME:R-HSA-381038",
"REACTOME:R-HSA-4085023",
"REACTOME:R-HSA-446210",
"REACTOME:R-MMU-446210",
"REACTOME:R-RNO-446210"
] | 11 | [
"1jxa",
"1moq",
"1mor",
"1mos",
"2j6h",
"2vf4",
"2vf5",
"3ooj",
"3tbf",
"4amv",
"4s1w",
"6r4e",
"6r4f",
"6r4g",
"6r4h",
"6r4i",
"6r4j",
"6svm",
"6svo",
"6svp",
"6svq",
"6zmj",
"6zmk",
"7dnr",
"7ndl"
] | 25 | [
"PUB00085441",
"PUB00085614"
] | [
"12044898",
"9914248"
] | [
"Glucosamine-6-phosphate synthase--the multi-facets enzyme.",
"Glutamine PRPP amidotransferase: snapshots of an enzyme in action."
] | [
2002,
1998
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Nucleocytoviricota",
"unclassified sequences"
] | [
1217,
27279,
4374,
47,
479
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus"
... | [
2,
2,
4,
11,
1,
7,
3,
1,
4,
12
] | 10 | true | Family | Glucosamine-fructose-6-phosphate aminotransferase, isomerising | Glucosamine-fructose-6-phosphate aminotransferase, isomerising | GFAT | 4 |
IPR005856 | 5,856 | Cysteine synthase | Cys_synth | Family | 34,153 | false | false | Cysteine synthase (also known as O-acetylserine (thiol)-lyase or O-acetyl-L-serine sulfhydrylase) is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulphide with the concomitant release of acetic acid. In bacteria such two forms of the enzyme are known (genes cysK and cysM) [ , ]... | [
"GO:0004124",
"GO:0006535"
] | [
"cysteine synthase activity",
"L-cysteine biosynthetic process from L-serine"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01136"
] | [
"cysKM"
] | [
34153
] | 1 | [
"EC",
"GP",
"METACYC",
"REACTOME",
"REACTOME"
] | [
"2.5.1.47",
"GenProp1301",
"PWY-6936",
"R-MTU-936654",
"R-MTU-936721"
] | [
"EC:2.5.1.47",
"GP:GenProp1301",
"METACYC:PWY-6936",
"REACTOME:R-MTU-936654",
"REACTOME:R-MTU-936721"
] | 5 | [
"1d6s",
"1fcj",
"1o58",
"1oas",
"1ve1",
"1y7l",
"1z7w",
"1z7y",
"2bhs",
"2bht",
"2eco",
"2ecq",
"2efy",
"2egu",
"2isq",
"2jc3",
"2pqm",
"2q3b",
"2q3c",
"2q3d",
"2v03",
"3bm5",
"3dki",
"3dwg",
"3dwi",
"3fca",
"3fgp",
"3iqg",
"3iqh",
"3iqi",
"3rr2",
"3spx"... | 101 | [
"PUB00051405",
"PUB00074572",
"PUB00074573"
] | [
"18799456",
"10889265",
"22113557"
] | [
"Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria.",
"beta-Cyanoalanine synthase is a mitochondrial cysteine synthase-like protein in spinach and Arabidopsis.",
"CysK from Lactobacillus casei enc... | [
2008,
2000,
2012
] | 3 | [
"IPR050214"
] | [
"IPR005858",
"IPR005859"
] | 1 | 2 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"Teubervirus",
"unclassified sequences"
] | [
222,
29022,
4516,
9,
384
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
29,
4,
2,
25,
29
] | 5 | true | Family | Cysteine synthase | Cysteine synthase | Cys_synth | 6 |
IPR005857 | 5,857 | Cystathionine beta-synthase | Cysta_beta_synth | Family | 7,626 | false | false | Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. Cysteine synthase (O-acetylserine (thiol)-lyase) is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulphide with the concomitant release of acetic acid -the function of many... | [
"GO:0004122",
"GO:0019343",
"GO:0005737"
] | [
"cystathionine beta-synthase activity",
"L-cysteine biosynthetic process via L-cystathionine",
"cytoplasm"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"NCBIFAM"
] | [
"TIGR01137"
] | [
"cysta_beta"
] | [
7626
] | 1 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"METACYC",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"4.2.1.22",
"GenProp1238",
"GenProp1399",
"GenProp1654",
"GenProp1685",
"PWY-801",
"PWY-8359",
"R-DDI-1614603",
"R-HSA-1614603",
"R-HSA-2408508",
"R-MMU-1614603",
"R-RNO-1614603",
"R-SCE-1614603"
] | [
"EC:4.2.1.22",
"GP:GenProp1238",
"GP:GenProp1399",
"GP:GenProp1654",
"GP:GenProp1685",
"METACYC:PWY-801",
"METACYC:PWY-8359",
"REACTOME:R-DDI-1614603",
"REACTOME:R-HSA-1614603",
"REACTOME:R-HSA-2408508",
"REACTOME:R-MMU-1614603",
"REACTOME:R-RNO-1614603",
"REACTOME:R-SCE-1614603"
] | 13 | [
"1jbq",
"1m54",
"3pc2",
"3pc3",
"3pc4",
"4coo",
"4l0d",
"4l27",
"4l28",
"4l3v",
"4pcu",
"5mms",
"5ohx",
"6c2h",
"6c2q",
"6c2z",
"6c4p",
"6xwl",
"6xyl",
"6y21",
"6z3s",
"6zs7",
"7qgt",
"7xnz",
"7xoh",
"7xoy",
"7xrq",
"8s5h",
"8s5i",
"8s5j",
"8s5k",
"8s5l"... | 35 | [
"PUB00077989",
"PUB00077990",
"PUB00077991",
"PUB00077992"
] | [
"23981774",
"20506325",
"23974653",
"1301198"
] | [
"Characterization of two pathogenic mutations in cystathionine beta-synthase: different intracellular locations for wild-type and mutant proteins.",
"Cystathionine beta-synthase mutations: effect of mutation topology on folding and activity.",
"Reduced response of Cystathionine Beta-Synthase (CBS) to S-Adenosyl... | [
2013,
2010,
2014,
1992
] | 4 | [
"IPR050214"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Candidatus Marsarchaeota group 2",
"Eukaryota",
"metagenomes"
] | [
3659,
3,
3936,
28
] | 4 | [
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
4,
1,
4,
1,
1,
6,
1
] | 7 | true | Family | Cystathionine beta-synthase | Cystathionine beta-synthase | Cysta_beta_synth | 4 |
IPR005858 | 5,858 | Cysteine synthase CysM | CysM | Family | 6,086 | false | false | Cysteine synthase (O-acetylserine (thiol)-lyase, ) is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulphide with the concomitant release of acetic acid. In bacteria such two forms of the enzyme are known (genes cysK and cysM). CysM differs from CysK ( ) in that it can also use ... | [
"GO:0004124",
"GO:0006535"
] | [
"cysteine synthase activity",
"L-cysteine biosynthetic process from L-serine"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01138"
] | [
"cysM"
] | [
6086
] | 1 | [
"EC",
"GP",
"GP",
"METACYC"
] | [
"2.5.1.47",
"GenProp0218",
"GenProp1301",
"PWY-6936"
] | [
"EC:2.5.1.47",
"GP:GenProp0218",
"GP:GenProp1301",
"METACYC:PWY-6936"
] | 4 | [
"2bhs",
"2bht",
"2jc3",
"2v03"
] | 4 | [] | [] | [] | [] | 0 | [
"IPR005856"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
6004,
22,
60
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Cysteine synthase CysM | Cysteine synthase CysM | CysM | 8 |
IPR005859 | 5,859 | Cysteine synthase CysK | CysK | Family | 24,933 | false | false | Cysteine synthase (O-acetylserine (thiol)-lyase, ) is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulphide with the concomitant release of acetic acid. In bacteria such two forms of the enzyme are known (genes cysK and cysM). CysK differs from CysM in that it can also use sulp... | [
"GO:0004124",
"GO:0006535"
] | [
"cysteine synthase activity",
"L-cysteine biosynthetic process from L-serine"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01139"
] | [
"cysK"
] | [
24933
] | 1 | [
"EC",
"GP",
"GP",
"METACYC",
"REACTOME"
] | [
"2.5.1.47",
"GenProp0218",
"GenProp1301",
"PWY-6936",
"R-MTU-936721"
] | [
"EC:2.5.1.47",
"GP:GenProp0218",
"GP:GenProp1301",
"METACYC:PWY-6936",
"REACTOME:R-MTU-936721"
] | 5 | [
"1d6s",
"1fcj",
"1o58",
"1oas",
"1ve1",
"1y7l",
"1z7w",
"1z7y",
"2eco",
"2ecq",
"2efy",
"2egu",
"2isq",
"2pqm",
"2q3b",
"2q3c",
"2q3d",
"3bm5",
"3fca",
"3iqg",
"3iqh",
"3iqi",
"3rr2",
"3spx",
"3t4p",
"3tbh",
"3vbe",
"3vc3",
"3x43",
"3x44",
"3zei",
"4aec"... | 86 | [
"PUB00074572"
] | [
"10889265"
] | [
"beta-Cyanoalanine synthase is a mitochondrial cysteine synthase-like protein in spinach and Arabidopsis."
] | [
2000
] | 1 | [
"IPR005856"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"Teubervirus",
"unclassified sequences"
] | [
214,
19977,
4519,
9,
214
] | 5 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
29,
4,
1,
25,
29
] | 5 | true | Family | Cysteine synthase CysK | Cysteine synthase CysK | CysK | 4 |
IPR005860 | 5,860 | L-threonine-O-3-phosphate decarboxylase | CobD | Family | 6,697 | false | false | L-threonine-O-3-phosphate decarboxylase (CobD) was shown to decarboxylate L-threonine O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, which is the precursor for the linkage between the nucleotide loop and the corrin ring in the biosynthesis of cobalamin [ ]. The molecule is a dimer where each subunit consi... | [
"GO:0003824",
"GO:0009236"
] | [
"catalytic activity",
"cobalamin biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"NCBIFAM"
] | [
"TIGR01140"
] | [
"L_thr_O3P_dcar"
] | [
6697
] | 1 | [
"EC",
"GP",
"GP",
"METACYC"
] | [
"4.1.1.81",
"GenProp0269",
"GenProp1312",
"PWY-5443"
] | [
"EC:4.1.1.81",
"GP:GenProp0269",
"GP:GenProp1312",
"METACYC:PWY-5443"
] | 4 | [
"1lc5",
"1lc7",
"1lc8",
"1lkc",
"9jfb",
"9jff"
] | 6 | [
"PUB00007899",
"PUB00007900"
] | [
"9446573",
"11939774"
] | [
"CobD, a novel enzyme with L-threonine-O-3-phosphate decarboxylase activity, is responsible for the synthesis of (R)-1-amino-2-propanol O-2-phosphate, a proposed new intermediate in cobalamin biosynthesis in Salmonella typhimurium LT2.",
"Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase ... | [
1998,
2002
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"metagenomes"
] | [
191,
6452,
54
] | 3 | [] | [] | 0 | true | Family | L-threonine-O-3-phosphate decarboxylase | L-threonine-O-3-phosphate decarboxylase | CobD | 7 |
IPR005861 | 5,861 | Histidinol-phosphate aminotransferase family | HisP_aminotrans | Family | 35,801 | false | false | The histidinol phosphate aminotransferase family consists of class I pyridoxal-5'-phosphate (PLP)-dependent enzymes that catalyze a step of L-histidine biosynthesis [ ]. These proteins are highly specific enzymes in the sense that no other aminotransferases are known to be capable of utilizing imidazoleacetol phosphate... | [
"GO:0004400",
"GO:0000105"
] | [
"histidinol-phosphate transaminase activity",
"L-histidine biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_01023",
"TIGR01141"
] | [
"HisC_aminotrans_2",
"hisC"
] | [
34899,
33731
] | 2 | [
"EC",
"GP"
] | [
"2.6.1.9",
"GenProp0109"
] | [
"EC:2.6.1.9",
"GP:GenProp0109"
] | 2 | [
"1fg3",
"1fg7",
"1gew",
"1gex",
"1gey",
"1h1c",
"1iji",
"1uu0",
"1uu1",
"1uu2",
"2f8j",
"3cq4",
"3cq5",
"3cq6",
"3euc",
"3ffh",
"3get",
"3hdo",
"4r2n",
"4r5z",
"4r8d",
"4rae",
"7szp",
"8bj1",
"8bj2",
"8bj3",
"8bj4"
] | 27 | [
"PUB00056758"
] | [
"8636014"
] | [
"Evolutionary recruitment of biochemically specialized subdivisions of Family I within the protein superfamily of aminotransferases."
] | [
1996
] | 1 | [] | [
"IPR024892"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
791,
32152,
2328,
530
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
6,
1,
1,
4,
1,
1,
3
] | 7 | true | Family | Histidinol-phosphate aminotransferase family | Histidinol-phosphate aminotransferase family | HisP_aminotrans | 6 |
IPR005862 | 5,862 | Formate-dependent phosphoribosylglycinamide formyltransferase | PurT | Family | 8,672 | false | false | The formation of isocyanate, a precursor of adenylate and guanylate, from 5-phosphoribosyl 1-pyrophosphate in the de novo purine biosynthesis pathway is basically composed of 10 steps of reactions [ ]. Formate-dependent phosphoribosylglycinamide formyltransferase (PurT, also known as phosphoribosylglycinamide formyltra... | [
"GO:0000287",
"GO:0004644",
"GO:0005524",
"GO:0016742",
"GO:0009152"
] | [
"magnesium ion binding",
"phosphoribosylglycinamide formyltransferase activity",
"ATP binding",
"hydroxymethyl-, formyl- and related transferase activity",
"purine ribonucleotide biosynthetic process"
] | [
"molecular_function",
"molecular_function",
"molecular_function",
"molecular_function",
"biological_process"
] | 5 | [
"HAMAP",
"NCBIFAM",
"NCBIFAM"
] | [
"MF_01643",
"NF006766",
"TIGR01142"
] | [
"PurT",
"PRK09288.1",
"purT"
] | [
8147,
8671,
7644
] | 3 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"METACYC"
] | [
"6.3.1.21",
"GenProp0110",
"GenProp1543",
"GenProp1628",
"GenProp1689",
"GenProp1749",
"GenProp1762",
"PWY-6122",
"PWY-6277"
] | [
"EC:6.3.1.21",
"GP:GenProp0110",
"GP:GenProp1543",
"GP:GenProp1628",
"GP:GenProp1689",
"GP:GenProp1749",
"GP:GenProp1762",
"METACYC:PWY-6122",
"METACYC:PWY-6277"
] | 9 | [
"1eyz",
"1ez1",
"1kj8",
"1kj9",
"1kji",
"1kjj",
"1kjq",
"2czg",
"2dwc",
"6khr"
] | 10 | [
"PUB00014229",
"PUB00033185"
] | [
"11953435",
"10079286"
] | [
"PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site.",
"Identification of new members of the GS ADP-forming family from the de novo purine biosynthesis pathway."
] | [
2002,
1999
] | 2 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"metagenomes"
] | [
184,
8394,
14,
80
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Formate-dependent phosphoribosylglycinamide formyltransferase | Formate-dependent phosphoribosylglycinamide formyltransferase | PurT | 7 |
IPR005863 | 5,863 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | UDP-N-AcMur_synth | Family | 25,754 | false | false | The bacterial cell wall provides strength and rigidity to counteract internal osmotic pressure, and protection against the environment. The peptidoglycan layer gives the cell wall its strength, and helps maintain the overall shape of the cell. The basic peptidoglycan structure of both Gram-positive and Gram-negative ba... | [
"GO:0005524",
"GO:0047480",
"GO:0071555"
] | [
"ATP binding",
"UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity",
"cell wall organization"
] | [
"molecular_function",
"molecular_function",
"biological_process"
] | 3 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_02019",
"TIGR01143"
] | [
"MurF",
"murF"
] | [
24519,
25518
] | 2 | [
"EC",
"GP",
"GP",
"METACYC",
"METACYC",
"METACYC"
] | [
"6.3.2.10",
"GenProp1448",
"GenProp1480",
"PWY-6386",
"PWY-6387",
"PWY-7953"
] | [
"EC:6.3.2.10",
"GP:GenProp1448",
"GP:GenProp1480",
"METACYC:PWY-6386",
"METACYC:PWY-6387",
"METACYC:PWY-7953"
] | 6 | [
"1gg4",
"2am1",
"2am2",
"3zl8",
"3zm5",
"3zm6",
"4cvk",
"4cvl",
"4cvm",
"4qdi",
"4qf5",
"4ziy"
] | 12 | [
"PUB00007902",
"PUB00035788",
"PUB00035789",
"PUB00035790",
"PUB00035791",
"PUB00035792",
"PUB00101154"
] | [
"11090285",
"17139082",
"17427948",
"16595662",
"16322581",
"16934839",
"18974047"
] | [
"Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 A resolution.",
"Structure of Escherichia coli UDP-N-acetylmuramoyl:L-alanine ligase (MurC).",
"Targeted molecular dynamics simulation studies of binding and conformational changes in E. coli MurD.",
"Th... | [
2000,
2006,
2007,
2006,
2005,
2006,
2008
] | 7 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"unclassified sequences",
"uncultured marine group II/III euryarchaeote KM3_94_C01"
] | [
25122,
179,
452,
1
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | UDP-N-AcMur_synth | 2 |
IPR005864 | 5,864 | ATP synthase, F0 complex, subunit b, bacterial | ATP_synth_F0_bsu_bac | Family | 19,565 | false | false | Transmembrane ATPases are membrane-bound enzyme complexes/ion transporters that use ATP hydrolysis to drive the transport of protons across a membrane. Some transmembrane ATPases also work in reverse, harnessing the energy from a proton gradient, using the flux of ions across the membrane via the ATPase proton channel ... | [
"GO:0015078",
"GO:0015986",
"GO:0045259"
] | [
"proton transmembrane transporter activity",
"proton motive force-driven ATP synthesis",
"proton-transporting ATP synthase complex"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"NCBIFAM"
] | [
"TIGR01144"
] | [
"ATP_synt_b"
] | [
19565
] | 1 | [
"GP"
] | [
"GenProp0128"
] | [
"GP:GenProp0128"
] | 1 | [
"5t4o",
"5t4p",
"5t4q",
"6n2d",
"6n2y",
"6n2z",
"6n30",
"6oqr",
"6oqs",
"6vwk",
"7jg5",
"7jg6",
"7jg7",
"7jg8",
"7jg9",
"7jga",
"7jgb",
"7jgc",
"7njk",
"7njl",
"7njm",
"7njn",
"7njo",
"7njp",
"7njq",
"7njr",
"7njs",
"7njt",
"7nju",
"7njv",
"7njw",
"7njx"... | 83 | [
"PUB00009752",
"PUB00020603",
"PUB00020604",
"PUB00020607",
"PUB00068786",
"PUB00068787",
"PUB00068788",
"PUB00068789"
] | [
"11309608",
"15473999",
"15078220",
"16045926",
"20450191",
"18937357",
"1385979",
"9741106"
] | [
"Resolution of distinct rotational substeps by submillisecond kinetic analysis of F1-ATPase.",
"The evolution of A-, F-, and V-type ATP synthases and ATPases: reversals in function and changes in the H+/ATP coupling ratio.",
"Mechanisms of ATPases--a multi-disciplinary approach.",
"Structure of the F1-binding... | [
2001,
2004,
2004,
2005,
2010,
2008,
1992,
1998
] | 8 | [
"IPR002146"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"Halogranum amylolyticum",
"unclassified sequences"
] | [
19152,
78,
1,
334
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | ATP synthase, F0 complex, subunit b, bacterial | ATP synthase, F0 complex, subunit b, bacterial | ATP_synth_F0_bsu_bac | 4 |
IPR005865 | 5,865 | Tetrahydromethanopterin S-methyltransferase, subunit C | THM_MeTrfase_su_C | Family | 229 | false | false | This entry represents the N5-methyltetrahydromethanopterin: coenzyme M methyltransferase subunit C in methanogenic archaea. This methyltranferase is a membrane-associated enzyme complex that uses methyl-transfer reaction to drive a sodium-ion pump. Archaea have evolved energy-yielding pathways marked by one-carbon bioc... | [
"GO:0030269",
"GO:0015948",
"GO:0016020"
] | [
"tetrahydromethanopterin S-methyltransferase activity",
"methanogenesis",
"membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"HAMAP",
"PFAM",
"PIRSF",
"NCBIFAM"
] | [
"MF_01096",
"PF04211",
"PIRSF006530",
"TIGR01148"
] | [
"MtrC",
"MtrC",
"MtrC",
"mtrC"
] | [
218,
229,
221,
227
] | 4 | [
"EC",
"GP",
"GP"
] | [
"7.2.1.4",
"GenProp0288",
"GenProp0722"
] | [
"EC:7.2.1.4",
"GP:GenProp0288",
"GP:GenProp0722"
] | 3 | [
"8q3v",
"8q54"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Cylicocyclus nassatus",
"ecological metagenomes"
] | [
223,
1,
5
] | 3 | [] | [] | 0 | true | Family | Tetrahydromethanopterin S-methyltransferase, subunit C | Tetrahydromethanopterin S-methyltransferase, subunit C | THM_MeTrfase_su_C | 9 |
IPR005866 | 5,866 | Tetrahydromethanopterin S-methyltransferase, subunit G | THM_MeTrfase_su_G | Family | 219 | false | false | This entry represents the N5-methyltetrahydromethanopterin: coenzyme M methyltransferase subunit G in methanogenic archaea. This methyltranferase is a membrane-associated enzyme complex that uses methyl-transfer reaction to drive a sodium-ion pump. Archaea have evolved energy-yielding pathways marked by one-carbon bioc... | [
"GO:0030269",
"GO:0015948",
"GO:0016020"
] | [
"tetrahydromethanopterin S-methyltransferase activity",
"methanogenesis",
"membrane"
] | [
"molecular_function",
"biological_process",
"cellular_component"
] | 3 | [
"HAMAP",
"PFAM",
"PIRSF",
"NCBIFAM"
] | [
"MF_01500",
"PF04210",
"PIRSF006500",
"TIGR01149"
] | [
"MtrG",
"MtrG",
"MtrG",
"mtrG"
] | [
218,
219,
133,
219
] | 4 | [
"EC",
"GP",
"GP"
] | [
"7.2.1.4",
"GenProp0288",
"GenProp0722"
] | [
"EC:7.2.1.4",
"GP:GenProp0288",
"GP:GenProp0722"
] | 3 | [
"8q3v",
"8q54"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Cylicocyclus nassatus",
"ecological metagenomes"
] | [
214,
1,
4
] | 3 | [] | [] | 0 | true | Family | Tetrahydromethanopterin S-methyltransferase, subunit G | Tetrahydromethanopterin S-methyltransferase, subunit G | THM_MeTrfase_su_G | 4 |
IPR005867 | 5,867 | Photosystem II protein D1 | PSII_D1 | Family | 21,101 | false | false | Oxygenic photosynthesis uses two multi-subunit photosystems (I and II) located in the cell membranes of cyanobacteria and in the thylakoid membranes of chloroplasts in plants and algae. Photosystem II (PSII) has a P680 reaction centre containing chlorophyll 'a' that uses light energy to carry out the oxidation (splitti... | [
"GO:0009055"
] | [
"electron transfer activity"
] | [
"molecular_function"
] | 1 | [
"HAMAP",
"NCBIFAM",
"CDD"
] | [
"MF_01379",
"TIGR01151",
"cd09289"
] | [
"PSII_PsbA_D1",
"psbA",
"Photosystem-II_D1"
] | [
17204,
21021,
15064
] | 3 | [
"EC",
"GP",
"METACYC"
] | [
"1.10.3.9",
"GenProp0661",
"PWY-101"
] | [
"EC:1.10.3.9",
"GP:GenProp0661",
"METACYC:PWY-101"
] | 3 | [
"1izl",
"1s5l",
"1w5c",
"2axt",
"3a0b",
"3a0h",
"3jcu",
"3kzi",
"3wu2",
"4fby",
"4il6",
"4ixq",
"4ixr",
"4pbu",
"4pj0",
"4rvy",
"4tnh",
"4tni",
"4tnj",
"4tnk",
"4ub6",
"4ub8",
"4v62",
"4v82",
"4yuu",
"5b5e",
"5b66",
"5e79",
"5e7c",
"5gth",
"5gti",
"5h2f"... | 168 | [
"PUB00015357",
"PUB00015358",
"PUB00015359",
"PUB00015386",
"PUB00015389",
"PUB00015390",
"PUB00097583",
"PUB00152828"
] | [
"12518057",
"15100025",
"14871485",
"15308630",
"10966643",
"15123635",
"30076221",
"33846594"
] | [
"Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.",
"The evolutionary development of the protein complement of photosystem 2.",
"The low molecular mass subunits of the photosynthetic supracomplex, photosystem II.",
"Evidence that D1 processing is requi... | [
2003,
2004,
2004,
2004,
2000,
2004,
2018,
2021
] | 8 | [
"IPR055266"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"Viruses",
"unclassified sequences"
] | [
816,
19660,
139,
486
] | 4 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
5,
7,
3
] | 3 | true | Family | Photosystem II protein D1 | Photosystem II protein D1 | PSII_D1 | 7 |
IPR005868 | 5,868 | Photosystem II D2 | PSII_PsbD/D2 | Family | 14,337 | false | false | This family represents the D2 protein (PsbD), which forms the reaction core of PSII as a heterodimer with the D1 protein. The accumulation of D2 protein appears to be a key step in the assembly of the PSII reaction centre complex [ ]. In higher plants, the N-terminal residues of both proteins, which are exposed to the ... | [
"GO:0015979",
"GO:0019684",
"GO:0009523",
"GO:0016020"
] | [
"photosynthesis",
"photosynthesis, light reaction",
"photosystem II",
"membrane"
] | [
"biological_process",
"biological_process",
"cellular_component",
"cellular_component"
] | 4 | [
"HAMAP",
"NCBIFAM",
"CDD"
] | [
"MF_01383",
"TIGR01152",
"cd09288"
] | [
"PSII_PsbD_D2",
"psbD",
"Photosystem-II_D2"
] | [
14275,
14327,
13274
] | 3 | [
"EC",
"GP",
"METACYC"
] | [
"1.10.3.9",
"GenProp0661",
"PWY-101"
] | [
"EC:1.10.3.9",
"GP:GenProp0661",
"METACYC:PWY-101"
] | 3 | [
"1izl",
"1s5l",
"1w5c",
"2axt",
"3a0b",
"3a0h",
"3jcu",
"3kzi",
"3wu2",
"4fby",
"4il6",
"4ixq",
"4ixr",
"4pbu",
"4pj0",
"4rvy",
"4tnh",
"4tni",
"4tnj",
"4tnk",
"4ub6",
"4ub8",
"4v62",
"4v82",
"4yuu",
"5b5e",
"5b66",
"5e79",
"5e7c",
"5gth",
"5gti",
"5h2f"... | 168 | [
"PUB00015357",
"PUB00015358",
"PUB00015359",
"PUB00015386",
"PUB00015388",
"PUB00097583",
"PUB00152828"
] | [
"12518057",
"15100025",
"14871485",
"15308630",
"15347679",
"30076221",
"33846594"
] | [
"Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.",
"The evolutionary development of the protein complement of photosystem 2.",
"The low molecular mass subunits of the photosynthetic supracomplex, photosystem II.",
"Evidence that D1 processing is requi... | [
2003,
2004,
2004,
2004,
2004,
2018,
2021
] | 7 | [
"IPR055266"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Caudoviricetes",
"Eukaryota"
] | [
298,
103,
13936
] | 3 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
6,
4,
3
] | 3 | true | Family | Photosystem II D2 | Photosystem II D2 | PSII_PsbD/D2 | 6 |
IPR005869 | 5,869 | Photosystem II CP43 reaction centre protein | PSII_PsbC | Family | 16,454 | false | false | This family represents the intrinsic antenna protein CP43 (PsbC), which is one of two such proteins found in the reaction centre of PSII, both of which can bind to chlorophyll 'a' and beta-carotene, passing the excitation energy on to the reaction centre [ ]. Oxygenic photosynthesis uses two multi-subunit photosystems ... | [
"GO:0016168",
"GO:0009772",
"GO:0015979",
"GO:0009523",
"GO:0016020"
] | [
"chlorophyll binding",
"photosynthetic electron transport in photosystem II",
"photosynthesis",
"photosystem II",
"membrane"
] | [
"molecular_function",
"biological_process",
"biological_process",
"cellular_component",
"cellular_component"
] | 5 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_01496",
"TIGR01153"
] | [
"PSII_PsbC_CP43",
"psbC"
] | [
15210,
16432
] | 2 | [
"GP"
] | [
"GenProp0661"
] | [
"GP:GenProp0661"
] | 1 | [
"1izl",
"1s5l",
"1w5c",
"2axt",
"3a0b",
"3a0h",
"3jcu",
"3kzi",
"3wu2",
"4fby",
"4il6",
"4ixq",
"4ixr",
"4pbu",
"4pj0",
"4rvy",
"4tnh",
"4tni",
"4tnj",
"4tnk",
"4ub6",
"4ub8",
"4v62",
"4v82",
"4yuu",
"5b5e",
"5b66",
"5e79",
"5e7c",
"5gth",
"5gti",
"5h2f"... | 165 | [
"PUB00015357",
"PUB00015358",
"PUB00015359",
"PUB00015360",
"PUB00097583",
"PUB00152828"
] | [
"12518057",
"15100025",
"14871485",
"12163077",
"30076221",
"33846594"
] | [
"Crystal structure of oxygen-evolving photosystem II from Thermosynechococcus vulcanus at 3.7-A resolution.",
"The evolutionary development of the protein complement of photosystem 2.",
"The low molecular mass subunits of the photosynthetic supracomplex, photosystem II.",
"Photosystem II: a multisubunit membr... | [
2003,
2004,
2004,
2002,
2018,
2021
] | 6 | [
"IPR000932"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota"
] | [
384,
16070
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
6,
4,
2
] | 3 | true | Family | Photosystem II CP43 reaction centre protein | Photosystem II CP43 reaction centre protein | PSII_PsbC | 8 |
IPR005870 | 5,870 | Cytochrome b6/f complex, subunit IV | Cyt_b6/f_cplx_suIV | Family | 14,636 | false | false | This entry describes subunit IV of the cytochrome b6/f complex. The cyt b6/f complex is central to the functions of oxygenic photosynthetic electron transport in cyanobacteria and its equivalents in algae and higher plants, mediating electron transfer between photosystem II (PSII) and photosystem I (PSI) reaction centr... | [
"GO:0009767",
"GO:0042651"
] | [
"photosynthetic electron transport chain",
"thylakoid membrane"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"HAMAP",
"PIRSF",
"NCBIFAM"
] | [
"MF_01344",
"PIRSF000033",
"TIGR01156"
] | [
"Cytb6_f_subIV",
"B6f_17K",
"cytb6_f_IV"
] | [
14128,
14434,
14624
] | 3 | [
"GP"
] | [
"GenProp1353"
] | [
"GP:GenProp1353"
] | 1 | [
"1q90",
"1vf5",
"2d2c",
"2e74",
"2e75",
"2e76",
"2zt9",
"4h0l",
"4h13",
"4h44",
"4i7z",
"4ogq",
"4pv1",
"6rqf",
"7qrm",
"7r0w",
"7zxy",
"7zyv",
"9es7",
"9es8",
"9es9"
] | 21 | [
"PUB00034763"
] | [
"16756511"
] | [
"Transmembrane traffic in the cytochrome b6f complex."
] | [
2006
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota"
] | [
385,
14251
] | 2 | [
"Arabidopsis thaliana",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
5,
3,
5
] | 3 | true | Family | Cytochrome b6/f complex, subunit IV | Cytochrome b6/f complex, subunit IV | Cyt_b6/f_cplx_suIV | 8 |
IPR005871 | 5,871 | Photosynthetic reaction centre, L subunit | Photo_RC_L | Family | 1,015 | false | false | This entry describes the photosynthetic reaction centre L subunit. The photosynthetic apparatus in non-oxygenic bacteria consists of light-harvesting (LH) protein-pigment complexes LH1 and LH2, which use carotenoid and bacteriochlorophyll as primary donors [ ]. LH1 acts as the energy collection hub, temporarily storing... | [
"GO:0019684",
"GO:0030077"
] | [
"photosynthesis, light reaction",
"plasma membrane light-harvesting complex"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"NCBIFAM",
"CDD"
] | [
"TIGR01157",
"cd09290"
] | [
"pufL",
"Photo-RC_L"
] | [
1009,
666
] | 2 | [
"GP"
] | [
"GenProp0662"
] | [
"GP:GenProp0662"
] | 1 | [
"1aig",
"1aij",
"1ds8",
"1dv3",
"1dv6",
"1dxr",
"1e14",
"1e6d",
"1eys",
"1f6n",
"1fnp",
"1fnq",
"1jgw",
"1jgx",
"1jgy",
"1jgz",
"1jh0",
"1k6l",
"1k6n",
"1kby",
"1l9b",
"1l9j",
"1m3x",
"1mps",
"1ogv",
"1pcr",
"1prc",
"1pss",
"1pst",
"1qov",
"1r2c",
"1rg5"... | 227 | [
"PUB00014111",
"PUB00014116",
"PUB00015279",
"PUB00015395",
"PUB00034760",
"PUB00034761",
"PUB00034762"
] | [
"11095707",
"11005826",
"2676514",
"12872158",
"15329728",
"16931113",
"8027023"
] | [
"Crystal structures of photosynthetic reaction center and high-potential iron-sulfur protein from Thermochromatium tepidum: thermostability and electron transfer.",
"Structural basis of the drastically increased initial electron transfer rate in the reaction center from a Rhodopseudomonas viridis mutant described... | [
2000,
2000,
1989,
2003,
2004,
2006,
1994
] | 7 | [
"IPR000484"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"freshwater sediment metagenome"
] | [
1012,
2,
1
] | 3 | [] | [] | 0 | true | Family | Photosynthetic reaction centre, L subunit | Photosynthetic reaction centre, L subunit | Photo_RC_L | 6 |
IPR005872 | 5,872 | Archaeal/bacterial translation initiation factor SUI1 | SUI1_arc_bac | Family | 8,423 | false | false | This family of archaeal and bacterial proteins is homologous to the eukaryotic translation intiation factor SUI1 involved in directing the ribosome to the proper start site of translation by functioning in concert with eIF-2 and the initiator tRNA-Met. The function of non-eukaryotic family members is unclear. Escherich... | [
"GO:0003743"
] | [
"translation initiation factor activity"
] | [
"molecular_function"
] | 1 | [
"PIRSF",
"NCBIFAM",
"CDD"
] | [
"PIRSF037511",
"TIGR01158",
"cd11567"
] | [
"Transl_init_SUI1_pro",
"SUI1_rel",
"YciH_like"
] | [
7347,
4090,
8347
] | 3 | [] | [] | [] | 0 | [
"1d1r",
"4mo0",
"5jb3",
"5jbh",
"5zcy"
] | 5 | [
"PUB00017639",
"PUB00080460"
] | [
"10497266",
"16362046"
] | [
"A phylogenetic approach to target selection for structural genomics: solution structure of YciH.",
"The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH."
] | [
1999,
2006
] | 2 | [] | [
"IPR022851"
] | 0 | 1 | 0 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
1116,
7142,
40,
125
] | 4 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Archaeal/bacterial translation initiation factor SUI1 | Archaeal/bacterial translation initiation factor SUI1 | SUI1_arc_bac | 3 |
IPR005873 | 5,873 | DENR, eukaryotes | DENR_eukaryotes | Family | 3,450 | false | false | This entry includes translation machinery-associated protein 22 (Tma22) from yeasts and density-regulated protein (DENR) from animals. DENR may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon [ ]. DENR and MCT-1 form a heterodimer, which binds to the ribosome and is in... | [
"GO:0003743"
] | [
"translation initiation factor activity"
] | [
"molecular_function"
] | 1 | [
"NCBIFAM"
] | [
"TIGR01159"
] | [
"DRP1"
] | [
3450
] | 1 | [] | [] | [] | 0 | [
"5vyc",
"6vpq",
"6vpr"
] | 3 | [
"PUB00090066",
"PUB00092572"
] | [
"20713520",
"30584092"
] | [
"Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling.",
"Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation."
] | [
2010,
2019
] | 2 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3450
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
4,
1,
1,
1,
2,
2,
1,
3,
3,
1,
1,
12
] | 12 | true | Family | DENR, eukaryotes | DENR, eukaryotes | DENR_eukaryotes | 6 |
IPR005874 | 5,874 | Eukaryotic translation initiation factor SUI1 | SUI1_euk | Family | 7,313 | false | false | SUI1/eIF1 (eukaryotic initiation factor 1) plays an important role in accurate initiator codon recognition during translation initiation. eIF1 interacts with 18S rRNA in the 40S ribosomal subunit during eukaryotic translation initiation. Point mutations in the yeast eIF1 implicate the protein in maintaining accurate st... | [
"GO:0003743"
] | [
"translation initiation factor activity"
] | [
"molecular_function"
] | 1 | [
"PIRSF",
"NCBIFAM",
"CDD"
] | [
"PIRSF004499",
"TIGR01160",
"cd11566"
] | [
"SUI1_euk",
"SUI1_MOF2",
"eIF1_SUI1"
] | [
5584,
6152,
7308
] | 3 | [] | [] | [] | 0 | [
"2if1",
"2ogh",
"2rvh",
"3j80",
"3j81",
"3jam",
"3jap",
"4bts",
"4kzx",
"4kzy",
"4uer",
"4v5o",
"6gsm",
"6gsn",
"6ybw",
"6zce",
"6zmw",
"6zp4",
"6zvj",
"7a09",
"7ase",
"7qp6",
"8cah",
"8pj1",
"8ppk",
"8ppl",
"8s8f",
"8s8i",
"8s8k",
"8xxn",
"9bln",
"9npx"... | 32 | [
"PUB00017640",
"PUB00080467"
] | [
"10376878",
"9488467"
] | [
"Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay.",
"The Mof2/Sui1 protein is a general monitor of translational accuracy."
] | [
1999,
1998
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"Megaviricetes",
"metagenomes"
] | [
4,
7285,
13,
11
] | 4 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
11,
1,
2,
2,
6,
6,
1,
12,
10,
1,
1,
17
] | 12 | true | Family | Eukaryotic translation initiation factor SUI1 | Eukaryotic translation initiation factor SUI1 | SUI1_euk | 5 |
IPR005875 | 5,875 | Phosphoribosylaminoimidazole carboxylase, ATPase subunit | PurK | Domain | 23,646 | false | false | Phosphoribosylaminoimidazole carboxylase is a fusion protein in plants and fungi, but consists of two non-interacting proteins in bacteria, PurK and PurE. This entry includes PurK, N5-carboxyaminoimidazole ribonucleotide (N5_CAIR) synthetase, which catalyzes the conversion of 5-aminoimidazole ribonucleotide (AIR), ATP,... | [
"GO:0004638",
"GO:0006189"
] | [
"phosphoribosylaminoimidazole carboxylase activity",
"'de novo' IMP biosynthetic process"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_01928",
"TIGR01161"
] | [
"PurK",
"purK"
] | [
23558,
23020
] | 2 | [
"EC",
"GP",
"GP",
"GP",
"GP",
"GP",
"METACYC",
"METACYC"
] | [
"6.3.4.18",
"GenProp0110",
"GenProp1406",
"GenProp1592",
"GenProp1730",
"GenProp1757",
"PWY-6123",
"PWY-7234"
] | [
"EC:6.3.4.18",
"GP:GenProp0110",
"GP:GenProp1406",
"GP:GenProp1592",
"GP:GenProp1730",
"GP:GenProp1757",
"METACYC:PWY-6123",
"METACYC:PWY-7234"
] | 8 | [
"1b6r",
"1b6s",
"2z04",
"3aw8",
"3ax6",
"3eth",
"3etj",
"3k5h",
"3k5i",
"3orq",
"3orr",
"3q2o",
"3qff",
"3r5h",
"3v4s",
"4dlk",
"4e4t",
"4izo",
"4m9u",
"4ma0",
"4ma5",
"4mam",
"5jqw"
] | 23 | [
"PUB00007904"
] | [
"10569930"
] | [
"Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily."
] | [
1999
] | 1 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
475,
20251,
2673,
247
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
6,
1,
1,
3,
1,
1,
15
] | 7 | true | Domain | Phosphoribosylaminoimidazole carboxylase, ATPase subunit | Phosphoribosylaminoimidazole carboxylase, ATPase subunit | PurK | 6 |
IPR005876 | 5,876 | Cobalt transport protein ATP-binding subunit | Co_trans_ATP-bd | Family | 4,700 | false | false | This entry represents the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. This superfamily includes two groups, one which catalyses the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small mo... | [
"GO:0006824"
] | [
"cobalt ion transport"
] | [
"biological_process"
] | 1 | [
"NCBIFAM"
] | [
"TIGR01166"
] | [
"cbiO"
] | [
4700
] | 1 | [
"GP"
] | [
"GenProp0277"
] | [
"GP:GenProp0277"
] | 1 | [
"3gfo",
"5x3x",
"5x40",
"5x41"
] | 4 | [
"PUB00004290",
"PUB00014769",
"PUB00017894",
"PUB00017895",
"PUB00017896",
"PUB00017897",
"PUB00017898",
"PUB00017899",
"PUB00025109",
"PUB00026406",
"PUB00043654"
] | [
"9872322",
"9873074",
"11421269",
"1282354",
"9640644",
"11988180",
"11470432",
"11402022",
"11080142",
"11532960",
"11421270"
] | [
"Crystal structure of the ATP-binding subunit of an ABC transporter.",
"Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters.",
"ABC transporters: physiology, structure and mechanism--an overview.",
"ABC transporters: from microorgani... | [
1998,
1999,
2001,
1992,
1998,
2002,
2001,
2001,
2000,
2001,
2001
] | 11 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"Myoviridae sp. ctWXg38",
"metagenomes"
] | [
428,
4213,
3,
1,
55
] | 5 | [] | [] | 0 | true | Family | Cobalt transport protein ATP-binding subunit | Cobalt transport protein ATP-binding subunit | Co_trans_ATP-bd | 5 |
IPR005877 | 5,877 | YSIRK Gram-positive signal peptide | YSIRK_signal_dom | Domain | 10,714 | false | false | Many surface proteins found in Streptococcus, Staphylococcus, and related lineages share apparently homologous signal sequences. A motif resembling [YF]SIRKxxxGxxS[VIA] appears at the start of the transmembrane domain. The GxxS motif appears perfectly conserved, suggesting a specific function and not just homology. | [] | [] | [] | 0 | [
"PFAM",
"NCBIFAM"
] | [
"PF04650",
"TIGR01168"
] | [
"YSIRK_signal",
"YSIRK_signal"
] | [
10010,
10525
] | 2 | [] | [] | [] | 0 | [
"5xyr",
"7uvk"
] | 2 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"human gut metagenome"
] | [
10704,
4,
6
] | 3 | [] | [] | 0 | true | Domain | YSIRK Gram-positive signal peptide | YSIRK Gram-positive signal peptide | YSIRK_signal_dom | 4 |
IPR005878 | 5,878 | Large ribosomal subunit protein uL1, bacteria | Ribosom_uL1_bact | Family | 24,908 | false | false | Ribosomal protein uL1 is the largest protein from the large ribosomal subunit. In Escherichia coli, uL1 is known to bind to the 23S rRNA. This model describe s bacterial and chloroplast ribosomal protein uL1. Most mitochondrial uL1 sequences are sufficiently divergent to be the contained in a different entry ( ). Ribos... | [
"GO:0003723",
"GO:0003735",
"GO:0006412",
"GO:0015934"
] | [
"RNA binding",
"structural constituent of ribosome",
"translation",
"large ribosomal subunit"
] | [
"molecular_function",
"molecular_function",
"biological_process",
"cellular_component"
] | 4 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_01318_B",
"TIGR01169"
] | [
"Ribosomal_uL1_B",
"rplA_bact"
] | [
24452,
24888
] | 2 | [] | [] | [] | 0 | [
"1ad2",
"1eg0",
"1ml5",
"1zho",
"2hw8",
"2om7",
"2rdo",
"3j3v",
"3j3w",
"3j46",
"3j5s",
"3j8g",
"3j9z",
"3ja1",
"3jcd",
"3jce",
"3qoy",
"3tg8",
"3u4m",
"3u56",
"3umy",
"487d",
"4csu",
"4f9t",
"4qg3",
"4qgb",
"4qvi",
"4reo",
"4u1u",
"4u1v",
"4u20",
"4u24"... | 274 | [
"PUB00007068",
"PUB00007069",
"PUB00007070"
] | [
"11297922",
"11290319",
"11114498"
] | [
"Atomic structures at last: the ribosome in 2000.",
"The ribosome in focus.",
"The end of the beginning: structural studies of ribosomal proteins."
] | [
2001,
2001,
2000
] | 3 | [
"IPR002143"
] | [] | 1 | 0 | 1 | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
2,
22924,
1575,
407
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Oryza sativa subsp. japonica",
"Zea mays"
] | [
8,
2,
4,
7
] | 4 | true | Family | Large ribosomal subunit protein uL1, bacteria | Large ribosomal subunit protein uL1, bacteria | Ribosom_uL1_bact | 4 |
IPR005880 | 5,880 | Large ribosomal subunit protein uL2, bacteria/organella | Ribosomal_uL2_bact_org | Family | 43,521 | false | false | The protein uL2 is found in all ribosomes and is one of the best conserved proteins of this mega-dalton complex. uL2 is elongated, exposing one end of the protein to the surface of the intersubunit interface of the 50 S subunit and is essential for the association of the ribosomal subunits and might participate in the ... | [
"GO:0003723",
"GO:0003735",
"GO:0016740",
"GO:0006412",
"GO:0015934"
] | [
"RNA binding",
"structural constituent of ribosome",
"transferase activity",
"translation",
"large ribosomal subunit"
] | [
"molecular_function",
"molecular_function",
"molecular_function",
"biological_process",
"cellular_component"
] | 5 | [
"HAMAP",
"NCBIFAM"
] | [
"MF_01320_B",
"TIGR01171"
] | [
"Ribosomal_uL2_B",
"rplB_bact"
] | [
38823,
43517
] | 2 | [] | [] | [] | 0 | [
"1c04",
"1ml5",
"1nkw",
"1nwx",
"1nwy",
"1rl2",
"1sm1",
"1vvj",
"1vy4",
"1vy5",
"1vy6",
"1vy7",
"1xbp",
"2j28",
"2rdo",
"2zjp",
"2zjq",
"2zjr",
"3bbx",
"3cf5",
"3dll",
"3j3v",
"3j3w",
"3j5l",
"3j6b",
"3j7z",
"3j8g",
"3j9w",
"3j9y",
"3j9z",
"3ja1",
"3jbu"... | 1,167 | [
"PUB00007068",
"PUB00007069",
"PUB00007070",
"PUB00007905"
] | [
"11297922",
"11290319",
"11114498",
"11114255"
] | [
"Atomic structures at last: the ribosome in 2000.",
"The ribosome in focus.",
"The end of the beginning: structural studies of ribosomal proteins.",
"Localization of the protein L2 in the 50 S subunit and the 70 S E. coli ribosome."
] | [
2001,
2001,
2000,
2001
] | 4 | [
"IPR002171"
] | [] | 1 | 0 | 1 | [
"Bacteria",
"Eukaryota",
"Methanobacteriota",
"unclassified sequences"
] | [
24303,
18754,
81,
383
] | 4 | [
"Arabidopsis thaliana",
"Escherichia coli (strain K12)",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
5,
1,
1,
5,
1,
1,
7
] | 7 | true | Family | Large ribosomal subunit protein uL2, bacteria/organella | Large ribosomal subunit protein uL2, bacteria/organella | Ribosomal_uL2_bact_org | 7 |
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