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Does Knockout of Alb in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Alb
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Alb (albumin) Type: protein-coding Summary: This gene encodes albumin, an abundant plasma protein essential for maintaining oncotic pressure that functions as a carrier protein for various molecules such as steriods and fatty acids in blood. This gene is primarily expressed in liver where the enco...
Does Knockout of GM21893 in macrophage causally result in phagocytosis?
0
1,888
Knockout
GM21893
phagocytosis
macrophage
Gene: Gm21893 (predicted gene, 21893) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Gja6 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Gja6
protein/peptide accumulation
Embryonic Cell Line
Gene: Gja6 (gap junction protein, alpha 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell communication, cell communication by electrical coupling, cell-cell signaling, heart development, transmembrane transport; CC: anchoring junction, connexin complex, gap junctio...
Does Knockout of Foxj2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Foxj2
protein/peptide accumulation
Embryonic Cell Line
Gene: Foxj2 (forkhead box J2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, male meiosis I, meiotic cell cycle, negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell differentiation, positive regulation of DNA-te...
Does Knockout of Plcb4 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Plcb4
autophagy
Embryonic Fibroblast Cell Line
Gene: Plcb4 (phospholipase C, beta 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular signal transduction, lipid catabolic process, lipid metabolic process, modulation of chemical synaptic transmission, negative regulation of potassium ion transport, phospha...
Does Knockout of Kank4 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Kank4
cell cycle progression
breast epithelium
Gene: Kank4 (KN motif and ankyrin repeat domains 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of actin filament polymerization, negative regulation of stress fiber assembly; CC: cytoplasm, cytoskeleton, cytosol, microtubule cytoskeleton ...
Does Knockout of Rhbdd2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Rhbdd2
cell proliferation
Mouse kidney carcinoma cell
Gene: Rhbdd2 (rhomboid domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: serine-type endopeptidase activity; CC: Golgi apparatus, Golgi membrane, membrane, nucleoplasm, perinuclear region of cytoplasm Pathways: UniProt: Q8VEK2 ...
Does Knockout of Cd99l2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Cd99l2
protein/peptide accumulation
Embryonic Cell Line
Gene: Cd99l2 (CD99 antigen-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, diapedesis, homotypic cell-cell adhesion, positive regulation of T cell extravasation, positive regulation of neutrophil extravasation; CC: adherens junction, anchoring junct...
Does Knockout of Lipo4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Lipo4
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Lipo4 (lipase, member O4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, lipid catabolic process, lipid metabolic process, sterol metabolic process; MF: hydrolase activity, hydrolase activity, acting on ester bonds, molecular_function, sterol es...
Does Knockout of Oca2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Oca2
protein/peptide distribution
myoblast cell line
Gene: Oca2 (oculocutaneous albinism II) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell population proliferation, chloride transmembrane transport, developmental pigmentation, lysosomal lumen pH elevation, melanin biosynthetic process, melanin biosynthetic process fr...
Does Knockout of Lipa in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Lipa
cell proliferation
Colonic Cancer Cell Line
Gene: Lipa (lysosomal acid lipase A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP biosynthetic process, T cell apoptotic process, T cell differentiation, T cell proliferation, TOR signaling, acute inflammatory response, adaptive thermogenesis, adipose tissue develo...
Does Knockout of Ccl26 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Ccl26
phagocytosis
macrophage
Gene: Ccl26 (C-C motif chemokine ligand 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell chemotaxis, antimicrobial humoral immune response mediated by antimicrobial peptide, chemokine-mediated signaling pathway, chemotaxis, eosinophil chemotaxis, immune response...
Does Knockout of Tbp in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Tbp
protein/peptide distribution
myoblast cell line
Gene: Tbp (TATA box binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription initiation, RNA polymerase I preinitiation complex assembly, RNA polymerase II preinitiation complex assembly, mRNA transcription by RNA polymerase II, positiv...
Does Knockout of Snapc5 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Snapc5
response to virus
Microglial Cell Line
Gene: Snapc5 (small nuclear RNA activating complex, polypeptide 5) Type: protein-coding Summary: Predicted to enable RNA polymerase II general transcription initiation factor activity and RNA polymerase III general transcription initiation factor activity. Predicted to be involved in snRNA transcription...
Does Knockout of Pigg in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Pigg
cell proliferation
Embryonic Stem Cell Line
Gene: Pigg (phosphatidylinositol glycan anchor biosynthesis, class G) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GPI anchor biosynthetic process; MF: CP2 mannose-ethanolamine phosphotransferase activity, mannose-ethanolamine phosphotransferase activity, transferase a...
Does Knockout of Polr1e in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Polr1e
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Polr1e (polymerase (RNA) I polypeptide E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, RNA polymerase I preinitiation complex assembly, nucleolar large rRNA transcription by RNA polymerase I, transcription elongation by RNA polymerase...
Does Knockout of Tmem196 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Tmem196
cell proliferation
Embryonic Stem Cell Line
Gene: Tmem196 (transmembrane protein 196) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: D3YWQ9 Entrez ID: 217951
Does Knockout of Elp6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Elp6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Elp6 (elongator acetyltransferase complex subunit 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, autophagosome maturation, autophagy, cellular response to stress, homeostasis of number of retina cells, inflammasome-mediated signaling pathway, ...
Does Knockout of Ptprt in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Ptprt
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ptprt (protein tyrosine phosphatase receptor type T) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor protein tyrosine kinase signaling pathway, cellular response to interleukin-6, homophilic cell adhesion via plasma membrane adhesion molecules,...
Does Knockout of Tmem154 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Tmem154
protein/peptide distribution
myoblast cell line
Gene: Tmem154 (transmembrane protein 154) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q8C4Q9 Entrez ID: 320782
Does Knockout of Bcap31 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Bcap31
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Bcap31 (B cell receptor associated protein 31) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, endoplasmic reticulum to Golgi vesicle-mediated transport, intracellular protein transport, positive regulation of ERAD pathway, positive regulation of ...
Does Knockout of Morn5 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Morn5
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Morn5 (MORN repeat containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cell projection, cellular_component, cilium, motile cilium, sperm flagellum Pathways: UniProt: Q9DAI9 Entrez ID: 75495
Does Knockout of 9230112D13Rik in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
9230112D13Rik
cell proliferation
Melanoma Cell Line
Gene: 9230112D13Rik (RIKEN cDNA 9230112D13 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9D260 Entrez ID: 78243
Does Knockout of Gm10220 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Gm10220
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Gm10220 (predicted gene 10220) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: K7N660 Entrez ID: 434689
Does Knockout of Micu2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Micu2
cell proliferation
Mouse kidney carcinoma cell
Gene: Micu2 (mitochondrial calcium uptake 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium import into the mitochondrion, cellular response to calcium ion, mitochondrial calcium ion homeostasis, mitochondrial calcium ion transmembrane transport, negative regulat...
Does Knockout of Gpd2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Gpd2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gpd2 (glycerol phosphate dehydrogenase 2, mitochondrial) Type: protein-coding Summary: Enables glycerol-3-phosphate dehydrogenase (quinone) activity. Involved in glycerol-3-phosphate shuttle. Acts upstream of or within camera-type eye development; gluconeogenesis; and glycerol-3-phosphate metaboli...
Does Knockout of Fkbp4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Fkbp4
cell proliferation
Mouse kidney carcinoma cell
Gene: Fkbp4 (FK506 binding protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: androgen receptor signaling pathway, copper ion transport, embryo implantation, male sex differentiation, negative regulation of microtubule polymerization, negative regulation of microt...
Does Knockout of Taf5l in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Taf5l
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Taf5l (TATA-box binding protein associated factor 5 like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of DNA-templated transcription, regulation of DNA repair, regulation of DNA-templated transcription, regulation of RNA splicing, regulation ...
Does Knockout of Wfdc8 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Wfdc8
protein/peptide distribution
myoblast cell line
Gene: Wfdc8 (WAP four-disulfide core domain 8) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: cellular_component, extracellular region, membrane Pathways: ...
Does Knockout of Pabpc2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Pabpc2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Pabpc2 (poly(A) binding protein, cytoplasmic 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of mRNA 3'-end processing; MF: RNA binding, mRNA 3'-UTR binding, nucleic aci...
Does Knockout of Gzmb in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Gzmb
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gzmb (granzyme B) Type: protein-coding Summary: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed...
Does Knockout of Sox9 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Sox9
cell proliferation
Embryonic Stem Cell Line
Gene: Sox9 (SRY (sex determining region Y)-box 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERK1 and ERK2 cascade, Harderian gland development, Notch signaling pathway, Sertoli cell development, Sertoli cell differentiation, anterior head development, aortic valve m...
Does Knockout of Mad2l2 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Mad2l2
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Mad2l2 (MAD2 mitotic arrest deficient-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA damage response, signal transduction resulting in transcription, DNA repair, actin filament organization, cell division, double-strand break repair...
Does Knockout of Rnd2 in Melanoma Cell Line causally result in cell proliferation?
1
1,158
Knockout
Rnd2
cell proliferation
Melanoma Cell Line
Gene: Rnd2 (Rho family GTPase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, positive regulation of collateral sprouting, regulation of actin cytoskeleton organization, signal transduction, small GTPase-mediated signal transduction; MF: GT...
Does Knockout of Rarb in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Rarb
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rarb (retinoic acid receptor, beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone development, camera-type eye development, cell differentiation, embryonic digestive tract development, embryonic eye morphogenesis, embryonic hindlimb morphogenesis, embryonic m...
Does Knockout of Nup214 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Nup214
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nup214 (nucleoporin 214) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, intracellular protein transport, mRNA export from nucleus, mRNA transport, nucleocytoplasmic transport, protein export from nucleus, protein import into nucleus, protei...
Does Knockout of Usp37 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Usp37
cell proliferation
Mouse kidney carcinoma cell
Gene: Usp37 (ubiquitin specific peptidase 37) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell division, protein K11-linked deubiquitination, protein K48-linked deubiquitination, protein deubiquitination, proteolysis, regulation ...
Does Knockout of Gsta3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Gsta3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Gsta3 (glutathione S-transferase, alpha 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aflatoxin catabolic process, glutathione metabolic process, lipid metabolic process, ureteric bud development, xenobiotic metabolic process; MF: dinitrosyl-iron complex bindin...
Does Knockout of Mbd4 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Mbd4
protein/peptide distribution
myoblast cell line
Gene: Mbd4 (methyl-CpG binding domain protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, intrinsic apoptotic signaling pathway in response to DNA damage, mitotic G2 DNA damage checkpoint signaling, response to radiation; MF: DNA bi...
Does Knockout of Adgrb2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Adgrb2
response to virus
Microglial Cell Line
Gene: Adgrb2 (adhesion G protein-coupled receptor B2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, calcineurin-NFAT signaling cascade, cell surface receptor signaling pathway, negative regulation of angiogenesis, peripheral...
Does Knockout of Zfp663 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Zfp663
protein/peptide distribution
myoblast cell line
Gene: Zfp663 (zinc finger protein 663) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of macromolecule metabolic process, regulation of primary metabolic process, regulation of transcription by RNA polymerase II; MF: ...
Does Knockout of Sco1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Sco1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sco1 (SCO1 cytochrome c oxidase assembly protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: copper ion homeostasis, cyclooxygenase pathway, gene expression, homeostasis of number of cells, immune response, intracellular copper ion homeostasis, intracellular ir...
Does Knockout of Vmn2r90 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Vmn2r90
cell proliferation
Mouse kidney carcinoma cell
Gene: Vmn2r90 (vomeronasal 2, receptor 90) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A33...
Does Knockout of Gprin1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Gprin1
cell proliferation
Mouse kidney carcinoma cell
Gene: Gprin1 (G protein-regulated inducer of neurite outgrowth 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: neuron projection development; CC: cell projection, growth cone, membrane, plasma membrane Pathways: UniProt: Q3UNH4 Entrez ID: 269...
Does Knockout of Fdps in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Fdps
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Fdps (farnesyl diphosphate synthetase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol biosynthetic process, cholesterol biosynthetic process via desmosterol, cholesterol biosynthetic process via lathosterol, cholesterol metabolic process, farnesyl dipho...
Does Knockout of Kcnn4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Kcnn4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kcnn4 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion transport, cardiac muscle hypertrophy, cell volume homeostasis, establishment of localization in cell, hepat...
Does Knockout of Cep72 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Cep72
protein/peptide distribution
myoblast cell line
Gene: Cep72 (centrosomal protein 72) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centriole replication, gamma-tubulin complex localization, regulation of protein localization to centrosome, spindle organization; CC: centriolar satellite, centrosome, ciliary basal body...
Does Knockout of Crhbp in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Crhbp
cell proliferation
Regulatory T cell
Gene: Crhbp (corticotropin releasing hormone binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: behavioral response to ethanol, cellular response to cAMP, cellular response to calcium ion, cellular response to cocaine, cellular response to estradiol stimulus...
Does Knockout of Timm23 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Timm23
cell proliferation
Embryonic Stem Cell Line
Gene: Timm23 (translocase of inner mitochondrial membrane 23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein import into mitochondrial matrix, protein transport, type 2 mitophagy; MF: enzyme binding, protein transmembrane transporter activity, transmembrane trans...
Does Knockout of Fkbp9 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Fkbp9
cell proliferation
Mouse kidney carcinoma cell
Gene: Fkbp9 (FK506 binding protein 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein folding; MF: calcium ion binding, isomerase activity, metal ion binding, peptidyl-prolyl cis-trans isomerase activity; CC: endoplasmic reticulum, endoplasmic reticulum lumen ...
Does Knockout of Smad7 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Smad7
protein/peptide distribution
myoblast cell line
Gene: Smad7 (SMAD family member 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: SMAD protein signal transduction, adherens junction assembly, anatomical structure morphogenesis, artery morphogenesis, beta-catenin destruction complex disassembly, cell differentiation, c...
Does Knockout of Wfdc15a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Wfdc15a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Wfdc15a (WAP four-disulfide core domain 15A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, defense response to bacterium, innate immune response; MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: ex...
Does Knockout of Lmbr1l in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Lmbr1l
cell proliferation
Mouse kidney carcinoma cell
Gene: Lmbr1l (limb region 1 like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell apoptotic process, T cell differentiation, T cell proliferation, Wnt signaling pathway, endocytosis, hematopoietic stem cell differentiation, negative regulation of canonical Wnt sign...
Does Knockout of Tiprl in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Tiprl
protein/peptide distribution
myoblast cell line
Gene: Tiprl (TIP41, TOR signalling pathway regulator-like (S. cerevisiae)) Type: protein-coding Summary: Predicted to enable protein phosphatase activator activity. Predicted to be involved in DNA damage checkpoint signaling and TOR signaling. Predicted to be located in cytoplasm. Predicted to be active...
Does Knockout of Atg9a in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,288
Knockout
Atg9a
cell proliferation
Mouse kidney carcinoma cell
Gene: Atg9a (autophagy related 9A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, bone morphogenesis, innate immune response, lipid transport, mitophagy, negative regulation of interferon-beta production, negative regulation of macropha...
Does Knockout of Havcr1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Havcr1
cell proliferation
Embryonic Stem Cell Line
Gene: Havcr1 (hepatitis A virus cellular receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: phagocytosis, engulfment, positive regulation of mast cell activation, response to lipopolysaccharide, response to wounding, symbiont entry into host cell; MF: phosphatidy...
Does Knockout of Skint7 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Skint7
protein/peptide accumulation
Regulatory T cell
Gene: Skint7 (selection and upkeep of intraepithelial T cells 7) Type: protein-coding Summary: Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be located in membrane. Predicted to b...
Does Knockout of Slc29a1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Slc29a1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Slc29a1 (solute carrier family 29 (nucleoside transporters), member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ADP catabolic process, AMP catabolic process, adenine transport, adenosine transport, cellular response to glucose stimulus, cellular response to h...
Does Knockout of Kcng3 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Kcng3
protein/peptide accumulation
Embryonic Cell Line
Gene: Kcng3 (potassium voltage-gated channel, subfamily G, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: action potential, monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport, protein...
Does Knockout of Etnk1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Etnk1
cell proliferation
Mouse kidney carcinoma cell
Gene: Etnk1 (ethanolamine kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glycerophospholipid biosynthetic process, lipid metabolic process, phosphatidylethanolamine biosynthetic process, phospholipid biosynthetic process; MF: ATP binding, ethanolamine kinase ac...
Does Knockout of Vti1b in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Vti1b
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Vti1b (vesicle transport through interaction with t-SNAREs 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to vacuole transport, intra-Golgi vesicle-mediated transport, intracellular protein transport, macroautophagy, protein transport, regulation of prote...
Does Knockout of Hsd17b2 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Hsd17b2
autophagy
Embryonic Fibroblast Cell Line
Gene: Hsd17b2 (hydroxysteroid (17-beta) dehydrogenase 2) Type: protein-coding Summary: Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)+] activity and testosterone dehydrogenase (NAD+) activity. Acts upstream of or within in utero embryonic development and placenta development. Predicted to b...
Does Knockout of Gfm1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Gfm1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Gfm1 (G elongation factor, mitochondrial 1) Type: protein-coding Summary: Predicted to enable GTPase activity and translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Located in mitochondrion. Is expressed in embryo and extraembryonic componen...
Does Knockout of Calm1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Calm1
cell proliferation
Colonic Cancer Cell Line
Gene: Calm1 (calmodulin 1) Type: protein-coding Summary: This gene encodes a member of the EF-hand calcium-binding protein family. The encoded protein acts as a calcium sensor and is involved in relaying signals to calcium-sensitive proteins, enzymes and ion channels. The protein-calcium complex binds t...
Does Knockout of Vps72 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Vps72
protein/peptide distribution
myoblast cell line
Gene: Vps72 (vacuolar protein sorting 72) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, positive regulation of DNA-templated transcription, positive regulation of double-strand break repair via homologous recombination, regulation of DNA-template...
Does Knockout of Ppp2r2d in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Ppp2r2d
protein/peptide accumulation
Mouse cell
Gene: Ppp2r2d (protein phosphatase 2, regulatory subunit B, delta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, exit from mitosis, mitotic cell cycle, regulation of chromosome segregation; MF: enzyme-substrate adaptor activity, protein phosphatase regula...
Does Knockout of Sema6c in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Sema6c
cell proliferation
Regulatory T cell
Gene: Sema6c (sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, cell differentiation, negative chemotaxis, negative regulation of axon extension, nervous system development, neur...
Does Knockout of Ctse in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Ctse
response to virus
Embryonic Fibroblast Cell Line
Gene: Ctse (cathepsin E) Type: protein-coding Summary: This gene encodes a member of the peptidase A1 family of aspartate proteases and preproprotein that is proteolytically processed to generate a mature protein product. The encoded protein may be involved in antigen processing and the maturation of se...
Does Knockout of Hace1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Hace1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Hace1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, membrane fusion, protein K48-linked ubiquitination, protein ubiquitination, regulation of cell migration, ubiquitin-d...
Does Knockout of Csnk2a1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Csnk2a1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Csnk2a1 (casein kinase 2, alpha 1 polypeptide) Type: protein-coding Summary: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. The k...
Does Knockout of Cdkn1b in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Cdkn1b
cell proliferation
Embryonic Stem Cell Line
Gene: Cdkn1b (cyclin dependent kinase inhibitor 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, Notch signaling pathway, autophagic cell death, cellular response to antibiotic, cellular response to lithium ion, heart development,...
Does Knockout of Ntn4 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Ntn4
cell proliferation
Regulatory T cell
Gene: Ntn4 (netrin 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ morphogenesis, axon guidance, basement membrane assembly, cell migration, neuron remodeling, regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithel...
Does Knockout of Efna3 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Efna3
protein/peptide distribution
myoblast cell line
Gene: Efna3 (ephrin A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, ephrin receptor signaling pathway, negative regulation of angiogenesis, positive regulation of amyloid precursor protein catabolic process, regulation of neuron differentiation; MF: eph...
Does Knockout of B230219D22Rik in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
B230219D22Rik
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: B230219D22Rik (RIKEN cDNA B230219D22 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q80X32 Entrez ID: 78521
Does Knockout of Prl8a2 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Prl8a2
protein/peptide accumulation
Regulatory T cell
Gene: Prl8a2 (prolactin family 8, subfamily a, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, female pregnancy, mammary gland development, maternal process involved in female pregnancy, positive regulation of lactation, ...
Does Knockout of Plcd4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Plcd4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Plcd4 (phospholipase C, delta 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acrosome reaction, intracellular signal transduction, lipid catabolic process, lipid metabolic process, phosphatidylinositol metabolic process, signal transduction, small GTPase-mediate...
Does Knockout of Mrps11 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Mrps11
cell proliferation
Embryonic Stem Cell Line
Gene: Mrps11 (mitochondrial ribosomal protein S11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribon...
Does Knockout of Mfsd5 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Mfsd5
cell viability
Immortal mouse chromaffin cells
Gene: Mfsd5 (major facilitator superfamily domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, molybdate ion transport, monoatomic ion transport, response to food, response to starvation; MF: molecular_function, molybdate ion transmemb...
Does Knockout of Fadd in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Fadd
cell proliferation
Melanoma Cell Line
Gene: Fadd (Fas associated via death domain) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, T cell differentiation in thymus, T cell homeostasis, TRAIL-activated apoptotic signaling pathway, apoptotic process, apoptotic signaling pathway, behavior...
Does Knockout of Hsd3b3 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Hsd3b3
protein/peptide distribution
myoblast cell line
Gene: Hsd3b3 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: C21-steroid hormone biosynthetic process, C21-steroid hormone metabolic process, androgen biosynthetic process, negative regulation ...
Does Knockout of Cox5b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Cox5b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cox5b (cytochrome c oxidase subunit 5B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, cytochrome c to oxygen, oxidative phosphorylation; CC: membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrial membrane, m...
Does Knockout of Elmo2 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Elmo2
protein/peptide distribution
myoblast cell line
Gene: Elmo2 (engulfment and cell motility 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, apoptotic process, cell chemotaxis, cell motility, phagocytosis; MF: SH3 domain binding, receptor tyrosine kinase binding; CC: cytoplasm, cytosol, mem...
Does Knockout of Cdk11b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Cdk11b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cdk11b (cyclin dependent kinase 11B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst development, mitotic sister chromatid cohesion, centromeric, negative regulation of apoptotic signaling pathway, regulation of RNA splicing, regulation of apoptotic proce...
Does Knockout of Tbx21 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Tbx21
protein/peptide distribution
myoblast cell line
Gene: Tbx21 (T-box 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, T-helper 1 cell lineage commitment, cell fate specification, lymphocyte migration, negative regulation of DNA-templated transcription, negative regulation of T-helper 17 cell di...
Does Knockout of Nup214 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Nup214
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Nup214 (nucleoporin 214) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, intracellular protein transport, mRNA export from nucleus, mRNA transport, nucleocytoplasmic transport, protein export from nucleus, protein import into nucleus, protei...
Does Knockout of Serpinb3b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Serpinb3b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Serpinb3b (serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B) Type: protein-coding Summary: No summary available. Gene Ontology: MF: cysteine-type endopeptidase inhibitor activity, enzyme binding, peptidase inhibitor activity, protease binding, serine-type endopepti...
Does Knockout of Dnttip2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Dnttip2
cell proliferation
Colonic Cancer Cell Line
Gene: Dnttip2 (deoxynucleotidyltransferase, terminal, interacting protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, ribosomal small subunit biogenesis; CC: chromosome, nucleolus, nucleoplasm, nucleus, small-subunit processome Pathways: ...
Does Knockout of Ccdc71 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Ccdc71
cell proliferation
Embryonic Stem Cell Line
Gene: Ccdc71 (coiled-coil domain containing 71) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8VEG0 Entrez ID: 72454
Does Knockout of Chmp4b in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Chmp4b
cell proliferation
Colonic Cancer Cell Line
Gene: Chmp4b (charged multivesicular body protein 4B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome maturation, autophagy, exit from mitosis, late endosome to lysosome transport, late endosome to vacuole transport via multivesicular body sorting pathway, m...
Does Knockout of Nol4l in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Nol4l
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Nol4l (nucleolar protein 4-like) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytosol, nucleoplasm Pathways: UniProt: Q3UH85, Q3TZG8, Q52KQ8 Entrez ID: 329540
Does Knockout of Fundc2 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Fundc2
protein/peptide distribution
myoblast cell line
Gene: Fundc2 (FUN14 domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy of mitochondrion, intracellular triglyceride homeostasis, regulation of platelet activation; MF: phosphatidylinositol-3,4,5-trisphosphate binding; CC: membrane, mitochondria...
Does Knockout of Cdr2l in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Cdr2l
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cdr2l (cerebellar degeneration-related protein 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: identical protein binding, molecular_function Pathways: UniProt: A2A6T1 Entrez ID: 237988
Does Knockout of Ddx55 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Ddx55
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ddx55 (DEAD box helicase 55) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of LSU-rRNA, rRNA processing, ribosome biogenesis; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, large ribo...
Does Knockout of Mtrf1l in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Mtrf1l
cell proliferation
Embryonic Stem Cell Line
Gene: Mtrf1l (mitochondrial translational release factor 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translational termination, translation, translational termination; MF: translation release factor activity, translation release factor activity, ...
Does Knockout of Neil3 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Neil3
cell proliferation
Embryonic Stem Cell Line
Gene: Neil3 (nei like 3 (E. coli)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, base-excision repair, interstrand cross-link repair, single strand break repair; MF: DNA N-glycosylase activity, DNA binding, DNA-(apurinic or apyrimidinic ...
Does Knockout of Schip1 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Schip1
cell cycle progression
breast epithelium
Gene: Schip1 (schwannomin interacting protein 1) Type: protein-coding Summary: Predicted to enable protein homodimerization activity. Acts upstream of or within several processes, including face morphogenesis; fibroblast migration; and luteinization. Predicted to be located in cytoplasm. Predicted to be...
Does Knockout of Tatdn2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Tatdn2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tatdn2 (TatD DNase domain containing 2) Type: protein-coding Summary: Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system. Orthologous to human TATDN2 (TatD DNase domain containing 2). [provided by Alliance of Genome Resour...
Does Knockout of Clec2e in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Clec2e
protein/peptide distribution
Microglial Cell Line
Gene: Clec2e (C-type lectin domain family 2, member e) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbohydrate binding, molecular_function, natural killer cell lectin-like receptor binding; CC: cell surface, endoplasmic reticulum, external side of plasma membrane, me...
Does Knockout of Nhej1 in Lymphoma Cell Line causally result in response to chemicals?
1
1,553
Knockout
Nhej1
response to chemicals
Lymphoma Cell Line
Gene: Nhej1 (non-homologous end joining factor 1) Type: protein-coding Summary: Predicted to enable DNA end binding activity and DNA polymerase binding activity. Involved in double-strand break repair via nonhomologous end joining. Predicted to be located in fibrillar center and nucleoplasm. Predicted t...
Does Knockout of Txndc12 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Txndc12
autophagy
Embryonic Fibroblast Cell Line
Gene: Txndc12 (thioredoxin domain containing 12 (endoplasmic reticulum)) Type: protein-coding Summary: Predicted to enable protein-disulfide reductase (glutathione) activity. Predicted to act upstream of or within negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling ...